id author title date pages extension mime words sentences flesch summary cache txt cord-016425-8yd2bkf1 Strobel, Gary Novel Natural Products From Rainforest Endophytes 2005 .txt text/plain 8998 471 44 It may also be true that a reduction in interest in natural products for use in drug development has happened as a result of people growing weary of dealing with the traditional sources of bioactive compounds, including plants of the temperate zones and microbes from a plethora of soil samples gathered in different parts of the world by armies of collectors. Frequently, many endophytes of the same species are isolated from the same plant, and only one or a few biotypes of a given fungus will produce a highly biologically active compound in culture (19) . Pestalotiopsis jesteri is a newly described endophytic fungal species from the Sepik River area of Papua New Guinea, and it produces jesterone and hydroxyjesterone, which exhibit antifungal activity against a variety of plant pathogenic fungi (30) . ./cache/cord-016425-8yd2bkf1.txt ./txt/cord-016425-8yd2bkf1.txt