id	sid	tid	token	lemma	pos
cord-018142-xt71w4nr	1	1	key	key	JJ
cord-018142-xt71w4nr	2	1	:	:	:
cord-018142-xt71w4nr	2	2	cord-018142-xt71w4nr	cord-018142-xt71w4nr	NN
cord-018142-xt71w4nr	2	3	authors	author	NNS
cord-018142-xt71w4nr	2	4	:	:	:
cord-018142-xt71w4nr	2	5	Samy	Samy	NNP
cord-018142-xt71w4nr	2	6	Modeliar	Modeliar	NNP
cord-018142-xt71w4nr	2	7	,	,	,
cord-018142-xt71w4nr	2	8	S.	S.	NNP
cord-018142-xt71w4nr	2	9	;	;	:
cord-018142-xt71w4nr	2	10	Monge	Monge	NNP
cord-018142-xt71w4nr	2	11	,	,	,
cord-018142-xt71w4nr	2	12	M.	M.	NNP
cord-018142-xt71w4nr	2	13	;	;	:
cord-018142-xt71w4nr	2	14	Slama	Slama	NNP
cord-018142-xt71w4nr	2	15	,	,	,
cord-018142-xt71w4nr	3	1	M.	M.	NNP
cord-018142-xt71w4nr	3	2	title	title	NN
cord-018142-xt71w4nr	3	3	:	:	:
cord-018142-xt71w4nr	3	4	Thrombotic	Thrombotic	NNP
cord-018142-xt71w4nr	3	5	Microangiopathy	Microangiopathy	NNP
cord-018142-xt71w4nr	3	6	Syndrome	Syndrome	NNP
cord-018142-xt71w4nr	3	7	in	in	IN
cord-018142-xt71w4nr	3	8	the	the	DT
cord-018142-xt71w4nr	3	9	ICU	ICU	NNP
cord-018142-xt71w4nr	3	10	date	date	NN
cord-018142-xt71w4nr	3	11	:	:	:
cord-018142-xt71w4nr	3	12	2006	2006	CD
cord-018142-xt71w4nr	3	13	journal	journal	NN
cord-018142-xt71w4nr	3	14	:	:	:
cord-018142-xt71w4nr	3	15	Yearbook	Yearbook	NNP
cord-018142-xt71w4nr	3	16	of	of	IN
cord-018142-xt71w4nr	3	17	Intensive	Intensive	NNP
cord-018142-xt71w4nr	3	18	Care	Care	NNP
cord-018142-xt71w4nr	3	19	and	and	CC
cord-018142-xt71w4nr	3	20	Emergency	Emergency	NNP
cord-018142-xt71w4nr	3	21	Medicine	Medicine	NNP
cord-018142-xt71w4nr	3	22	DOI	DOI	NNP
cord-018142-xt71w4nr	3	23	:	:	:
cord-018142-xt71w4nr	3	24	10.1007/3	10.1007/3	CD
cord-018142-xt71w4nr	3	25	-	-	HYPH
cord-018142-xt71w4nr	3	26	540	540	CD
cord-018142-xt71w4nr	3	27	-	-	HYPH
cord-018142-xt71w4nr	3	28	33396	33396	CD
cord-018142-xt71w4nr	4	1	-7_20	-7_20	NNP
cord-018142-xt71w4nr	4	2	sha	sha	NNP
cord-018142-xt71w4nr	4	3	:	:	:
cord-018142-xt71w4nr	4	4	b53d66837274c59928b2f0f3d7e0b73588359046	b53d66837274c59928b2f0f3d7e0b73588359046	NNP
cord-018142-xt71w4nr	4	5	doc_id	doc_id	CD
cord-018142-xt71w4nr	4	6	:	:	:
cord-018142-xt71w4nr	4	7	18142	18142	CD
cord-018142-xt71w4nr	4	8	cord_uid	cord_uid	NNS
cord-018142-xt71w4nr	4	9	:	:	:
cord-018142-xt71w4nr	5	1	xt71w4nr	xt71w4nr	XX
cord-018142-xt71w4nr	6	1	Major	major	JJ
cord-018142-xt71w4nr	6	2	studies	study	NNS
cord-018142-xt71w4nr	6	3	designed	design	VBN
cord-018142-xt71w4nr	6	4	to	to	TO
cord-018142-xt71w4nr	6	5	improve	improve	VB
cord-018142-xt71w4nr	6	6	our	-PRON-	PRP$
cord-018142-xt71w4nr	6	7	understanding	understanding	NN
cord-018142-xt71w4nr	6	8	of	of	IN
cord-018142-xt71w4nr	6	9	the	the	DT
cord-018142-xt71w4nr	6	10	pathophysiology	pathophysiology	NN
cord-018142-xt71w4nr	6	11	of	of	IN
cord-018142-xt71w4nr	6	12	TMA	TMA	NNP
cord-018142-xt71w4nr	6	13	have	have	VBP
cord-018142-xt71w4nr	6	14	been	be	VBN
cord-018142-xt71w4nr	6	15	conducted	conduct	VBN
cord-018142-xt71w4nr	6	16	over	over	IN
cord-018142-xt71w4nr	6	17	recent	recent	JJ
cord-018142-xt71w4nr	6	18	years	year	NNS
cord-018142-xt71w4nr	6	19	.	.	.
cord-018142-xt71w4nr	7	1	This	this	DT
cord-018142-xt71w4nr	7	2	improved	improve	VBN
cord-018142-xt71w4nr	7	3	knowledge	knowledge	NN
cord-018142-xt71w4nr	7	4	opens	open	VBZ
cord-018142-xt71w4nr	7	5	up	up	RP
cord-018142-xt71w4nr	7	6	new	new	JJ
cord-018142-xt71w4nr	7	7	perspectives	perspective	NNS
cord-018142-xt71w4nr	7	8	for	for	IN
cord-018142-xt71w4nr	7	9	more	more	RBR
cord-018142-xt71w4nr	7	10	targeted	target	VBN
cord-018142-xt71w4nr	7	11	treatment	treatment	NN
cord-018142-xt71w4nr	7	12	.	.	.
cord-018142-xt71w4nr	8	1	However	however	RB
cord-018142-xt71w4nr	8	2	,	,	,
cord-018142-xt71w4nr	8	3	until	until	IN
cord-018142-xt71w4nr	8	4	these	these	DT
cord-018142-xt71w4nr	8	5	innovative	innovative	JJ
cord-018142-xt71w4nr	8	6	treatments	treatment	NNS
cord-018142-xt71w4nr	8	7	become	become	VBP
cord-018142-xt71w4nr	8	8	available	available	JJ
cord-018142-xt71w4nr	8	9	,	,	,
cord-018142-xt71w4nr	8	10	early	early	JJ
cord-018142-xt71w4nr	8	11	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	8	12	of	of	IN
cord-018142-xt71w4nr	8	13	these	these	DT
cord-018142-xt71w4nr	8	14	diseases	disease	NNS
cord-018142-xt71w4nr	8	15	is	be	VBZ
cord-018142-xt71w4nr	8	16	essential	essential	JJ
cord-018142-xt71w4nr	8	17	in	in	IN
cord-018142-xt71w4nr	8	18	order	order	NN
cord-018142-xt71w4nr	8	19	to	to	TO
cord-018142-xt71w4nr	8	20	rapidly	rapidly	RB
cord-018142-xt71w4nr	8	21	initiate	initiate	VB
cord-018142-xt71w4nr	8	22	specific	specific	JJ
cord-018142-xt71w4nr	8	23	treatment	treatment	NN
cord-018142-xt71w4nr	8	24	,	,	,
cord-018142-xt71w4nr	8	25	as	as	IN
cord-018142-xt71w4nr	8	26	the	the	DT
cord-018142-xt71w4nr	8	27	interval	interval	NN
cord-018142-xt71w4nr	8	28	between	between	IN
cord-018142-xt71w4nr	8	29	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	8	30	and	and	CC
cord-018142-xt71w4nr	8	31	initiation	initiation	NN
cord-018142-xt71w4nr	8	32	of	of	IN
cord-018142-xt71w4nr	8	33	plasma	plasma	NN
cord-018142-xt71w4nr	8	34	exchange	exchange	NN
cord-018142-xt71w4nr	8	35	is	be	VBZ
cord-018142-xt71w4nr	8	36	a	a	DT
cord-018142-xt71w4nr	8	37	decisive	decisive	JJ
cord-018142-xt71w4nr	8	38	element	element	NN
cord-018142-xt71w4nr	8	39	in	in	IN
cord-018142-xt71w4nr	8	40	the	the	DT
cord-018142-xt71w4nr	8	41	prognosis	prognosis	NN
cord-018142-xt71w4nr	8	42	of	of	IN
cord-018142-xt71w4nr	8	43	TTP	TTP	NNP
cord-018142-xt71w4nr	8	44	.	.	.
cord-018142-xt71w4nr	9	1	Treatment	treatment	NN
cord-018142-xt71w4nr	9	2	must	must	MD
cord-018142-xt71w4nr	9	3	not	not	RB
cord-018142-xt71w4nr	9	4	be	be	VB
cord-018142-xt71w4nr	9	5	stopped	stop	VBN
cord-018142-xt71w4nr	9	6	too	too	RB
cord-018142-xt71w4nr	9	7	early	early	RB
cord-018142-xt71w4nr	9	8	or	or	CC
cord-018142-xt71w4nr	9	9	too	too	RB
cord-018142-xt71w4nr	9	10	rapidly	rapidly	RB
cord-018142-xt71w4nr	9	11	and	and	CC
cord-018142-xt71w4nr	9	12	must	must	MD
cord-018142-xt71w4nr	9	13	take	take	VB
cord-018142-xt71w4nr	9	14	into	into	IN
cord-018142-xt71w4nr	9	15	account	account	NN
cord-018142-xt71w4nr	9	16	the	the	DT
cord-018142-xt71w4nr	9	17	various	various	JJ
cord-018142-xt71w4nr	9	18	associated	associate	VBN
cord-018142-xt71w4nr	9	19	factors	factor	NNS
cord-018142-xt71w4nr	9	20	,	,	,
cord-018142-xt71w4nr	9	21	especially	especially	RB
cord-018142-xt71w4nr	9	22	the	the	DT
cord-018142-xt71w4nr	9	23	presence	presence	NN
cord-018142-xt71w4nr	9	24	of	of	IN
cord-018142-xt71w4nr	9	25	infection	infection	NN
cord-018142-xt71w4nr	9	26	.	.	.
cord-018142-xt71w4nr	10	1	z	z	LS
cord-018142-xt71w4nr	10	2	Pathophysiology	Pathophysiology	NNP
cord-018142-xt71w4nr	11	1	The	the	DT
cord-018142-xt71w4nr	11	2	early	early	JJ
cord-018142-xt71w4nr	11	3	phenomenon	phenomenon	NN
cord-018142-xt71w4nr	11	4	common	common	JJ
cord-018142-xt71w4nr	11	5	to	to	IN
cord-018142-xt71w4nr	11	6	all	all	DT
cord-018142-xt71w4nr	11	7	forms	form	NNS
cord-018142-xt71w4nr	11	8	of	of	IN
cord-018142-xt71w4nr	11	9	TMA	TMA	NNP
cord-018142-xt71w4nr	11	10	is	be	VBZ
cord-018142-xt71w4nr	11	11	damage	damage	NN
cord-018142-xt71w4nr	11	12	to	to	IN
cord-018142-xt71w4nr	11	13	,	,	,
cord-018142-xt71w4nr	11	14	or	or	CC
cord-018142-xt71w4nr	11	15	activation	activation	NN
cord-018142-xt71w4nr	11	16	of	of	IN
cord-018142-xt71w4nr	11	17	,	,	,
cord-018142-xt71w4nr	11	18	the	the	DT
cord-018142-xt71w4nr	11	19	vascular	vascular	JJ
cord-018142-xt71w4nr	11	20	endothelium	endothelium	NN
cord-018142-xt71w4nr	11	21	,	,	,
cord-018142-xt71w4nr	11	22	responsible	responsible	JJ
cord-018142-xt71w4nr	11	23	for	for	IN
cord-018142-xt71w4nr	11	24	local	local	JJ
cord-018142-xt71w4nr	11	25	platelet	platelet	NN
cord-018142-xt71w4nr	11	26	aggregation	aggregation	NN
cord-018142-xt71w4nr	11	27	,	,	,
cord-018142-xt71w4nr	11	28	promoting	promote	VBG
cord-018142-xt71w4nr	11	29	the	the	DT
cord-018142-xt71w4nr	11	30	formation	formation	NN
cord-018142-xt71w4nr	11	31	of	of	IN
cord-018142-xt71w4nr	11	32	platelet	platelet	NN
cord-018142-xt71w4nr	11	33	thrombi	thrombi	NN
cord-018142-xt71w4nr	11	34	in	in	IN
cord-018142-xt71w4nr	11	35	the	the	DT
cord-018142-xt71w4nr	11	36	microcirculation	microcirculation	NN
cord-018142-xt71w4nr	11	37	.	.	.
cord-018142-xt71w4nr	12	1	Various	various	JJ
cord-018142-xt71w4nr	12	2	factors	factor	NNS
cord-018142-xt71w4nr	12	3	are	be	VBP
cord-018142-xt71w4nr	12	4	responsible	responsible	JJ
cord-018142-xt71w4nr	12	5	for	for	IN
cord-018142-xt71w4nr	12	6	this	this	DT
cord-018142-xt71w4nr	12	7	endothelial	endothelial	JJ
cord-018142-xt71w4nr	12	8	cell	cell	NN
cord-018142-xt71w4nr	12	9	activation	activation	NN
cord-018142-xt71w4nr	12	10	:	:	:
cord-018142-xt71w4nr	12	11	infections	infection	NNS
cord-018142-xt71w4nr	12	12	,	,	,
cord-018142-xt71w4nr	12	13	drugs	drug	NNS
cord-018142-xt71w4nr	12	14	,	,	,
cord-018142-xt71w4nr	12	15	cancers	cancer	NNS
cord-018142-xt71w4nr	12	16	,	,	,
cord-018142-xt71w4nr	12	17	stem	stem	VBP
cord-018142-xt71w4nr	12	18	cell	cell	NN
cord-018142-xt71w4nr	12	19	transplantation	transplantation	NN
cord-018142-xt71w4nr	12	20	,	,	,
cord-018142-xt71w4nr	12	21	etc	etc	FW
cord-018142-xt71w4nr	12	22	.	.	.
cord-018142-xt71w4nr	13	1	[	[	-LRB-
cord-018142-xt71w4nr	13	2	2	2	CD
cord-018142-xt71w4nr	13	3	]	]	-RRB-
cord-018142-xt71w4nr	13	4	.	.	.
cord-018142-xt71w4nr	14	1	Role	role	NN
cord-018142-xt71w4nr	14	2	of	of	IN
cord-018142-xt71w4nr	14	3	von	von	NNP
cord-018142-xt71w4nr	14	4	Willebrand	Willebrand	NNP
cord-018142-xt71w4nr	14	5	factor	factor	NN
cord-018142-xt71w4nr	14	6	(	(	-LRB-
cord-018142-xt71w4nr	14	7	vWF	vWF	NNP
cord-018142-xt71w4nr	14	8	)	)	-RRB-
cord-018142-xt71w4nr	14	9	and	and	CC
cord-018142-xt71w4nr	14	10	ADAMTS-13	adamts-13	ADD
cord-018142-xt71w4nr	14	11	protein	protein	NN
cord-018142-xt71w4nr	14	12	(	(	-LRB-
cord-018142-xt71w4nr	14	13	A	a	DT
cord-018142-xt71w4nr	14	14	Disintegrin	Disintegrin	NNP
cord-018142-xt71w4nr	14	15	And	and	CC
cord-018142-xt71w4nr	14	16	Metalloprotease	Metalloprotease	NNP
cord-018142-xt71w4nr	14	17	with	with	IN
cord-018142-xt71w4nr	14	18	ThromboSpondin	ThromboSpondin	NNP
cord-018142-xt71w4nr	14	19	type	type	NN
cord-018142-xt71w4nr	14	20	1	1	CD
cord-018142-xt71w4nr	14	21	motif	motif	NN
cord-018142-xt71w4nr	14	22	)	)	-RRB-
cord-018142-xt71w4nr	14	23	.	.	.
cord-018142-xt71w4nr	15	1	Physiologically	physiologically	RB
cord-018142-xt71w4nr	15	2	,	,	,
cord-018142-xt71w4nr	15	3	vWF	vWF	NNP
cord-018142-xt71w4nr	15	4	is	be	VBZ
cord-018142-xt71w4nr	15	5	a	a	DT
cord-018142-xt71w4nr	15	6	multimeric	multimeric	JJ
cord-018142-xt71w4nr	15	7	glycoprotein	glycoprotein	NN
cord-018142-xt71w4nr	15	8	that	that	WDT
cord-018142-xt71w4nr	15	9	triggers	trigger	VBZ
cord-018142-xt71w4nr	15	10	the	the	DT
cord-018142-xt71w4nr	15	11	formation	formation	NN
cord-018142-xt71w4nr	15	12	of	of	IN
cord-018142-xt71w4nr	15	13	platelet	platelet	NN
cord-018142-xt71w4nr	15	14	clot	clot	NN
cord-018142-xt71w4nr	15	15	,	,	,
cord-018142-xt71w4nr	15	16	and	and	CC
cord-018142-xt71w4nr	15	17	transport	transport	NN
cord-018142-xt71w4nr	15	18	of	of	IN
cord-018142-xt71w4nr	15	19	clotting	clotting	NN
cord-018142-xt71w4nr	15	20	factor	factor	NN
cord-018142-xt71w4nr	15	21	VIII	VIII	NNP
cord-018142-xt71w4nr	15	22	.	.	.
cord-018142-xt71w4nr	16	1	It	-PRON-	PRP
cord-018142-xt71w4nr	16	2	is	be	VBZ
cord-018142-xt71w4nr	16	3	synthesized	synthesize	VBN
cord-018142-xt71w4nr	16	4	by	by	IN
cord-018142-xt71w4nr	16	5	megakaryocytes	megakaryocyte	NNS
cord-018142-xt71w4nr	16	6	and	and	CC
cord-018142-xt71w4nr	16	7	endothelial	endothelial	JJ
cord-018142-xt71w4nr	16	8	cells	cell	NNS
cord-018142-xt71w4nr	16	9	,	,	,
cord-018142-xt71w4nr	16	10	and	and	CC
cord-018142-xt71w4nr	16	11	then	then	RB
cord-018142-xt71w4nr	16	12	stored	store	VBN
cord-018142-xt71w4nr	16	13	in	in	IN
cord-018142-xt71w4nr	16	14	endothelial	endothelial	JJ
cord-018142-xt71w4nr	16	15	and	and	CC
cord-018142-xt71w4nr	16	16	platelet	platelet	NN
cord-018142-xt71w4nr	16	17	Weibel	Weibel	NNP
cord-018142-xt71w4nr	16	18	-	-	HYPH
cord-018142-xt71w4nr	16	19	Palade	Palade	NNP
cord-018142-xt71w4nr	16	20	bodies	body	NNS
cord-018142-xt71w4nr	16	21	.	.	.
cord-018142-xt71w4nr	17	1	Ultra	ultra	JJ
cord-018142-xt71w4nr	17	2	-	-	JJ
cord-018142-xt71w4nr	17	3	large	large	JJ
cord-018142-xt71w4nr	17	4	vWF	vwf	IN
cord-018142-xt71w4nr	17	5	multimers	multimer	NNS
cord-018142-xt71w4nr	17	6	(	(	-LRB-
cord-018142-xt71w4nr	17	7	ULvWF	ULvWF	NNP
cord-018142-xt71w4nr	17	8	)	)	-RRB-
cord-018142-xt71w4nr	17	9	are	be	VBP
cord-018142-xt71w4nr	17	10	composed	compose	VBN
cord-018142-xt71w4nr	17	11	of	of	IN
cord-018142-xt71w4nr	17	12	several	several	JJ
cord-018142-xt71w4nr	17	13	vWF	vwf	NN
cord-018142-xt71w4nr	17	14	monomers	monomer	NNS
cord-018142-xt71w4nr	17	15	linked	link	VBN
cord-018142-xt71w4nr	17	16	by	by	IN
cord-018142-xt71w4nr	17	17	disulfide	disulfide	JJ
cord-018142-xt71w4nr	17	18	bonds	bond	NNS
cord-018142-xt71w4nr	17	19	.	.	.
cord-018142-xt71w4nr	18	1	vWF	vWF	NNP
cord-018142-xt71w4nr	18	2	multimers	multimers	NNP
cord-018142-xt71w4nr	18	3	have	have	VBP
cord-018142-xt71w4nr	18	4	more	more	RBR
cord-018142-xt71w4nr	18	5	intense	intense	JJ
cord-018142-xt71w4nr	18	6	hemostatic	hemostatic	JJ
cord-018142-xt71w4nr	18	7	properties	property	NNS
cord-018142-xt71w4nr	18	8	than	than	IN
cord-018142-xt71w4nr	18	9	monomers	monomer	NNS
cord-018142-xt71w4nr	18	10	[	[	-LRB-
cord-018142-xt71w4nr	18	11	2	2	CD
cord-018142-xt71w4nr	18	12	]	]	-RRB-
cord-018142-xt71w4nr	18	13	.	.	.
cord-018142-xt71w4nr	19	1	The	the	DT
cord-018142-xt71w4nr	19	2	ADAMTS-13	adamts-13	DT
cord-018142-xt71w4nr	19	3	protein	protein	NN
cord-018142-xt71w4nr	19	4	is	be	VBZ
cord-018142-xt71w4nr	19	5	a	a	DT
cord-018142-xt71w4nr	19	6	metalloprotease	metalloprotease	NN
cord-018142-xt71w4nr	19	7	that	that	WDT
cord-018142-xt71w4nr	19	8	cleaves	cleave	VBZ
cord-018142-xt71w4nr	19	9	vWF	vwf	IN
cord-018142-xt71w4nr	19	10	multimers	multimers	NNP
cord-018142-xt71w4nr	19	11	into	into	IN
cord-018142-xt71w4nr	19	12	monomers	monomer	NNS
cord-018142-xt71w4nr	19	13	[	[	-LRB-
cord-018142-xt71w4nr	19	14	3	3	CD
cord-018142-xt71w4nr	19	15	,	,	,
cord-018142-xt71w4nr	19	16	4	4	CD
cord-018142-xt71w4nr	19	17	]	]	-RRB-
cord-018142-xt71w4nr	19	18	.	.	.
cord-018142-xt71w4nr	20	1	TTP	TTP	NNP
cord-018142-xt71w4nr	20	2	is	be	VBZ
cord-018142-xt71w4nr	20	3	associated	associate	VBN
cord-018142-xt71w4nr	20	4	with	with	IN
cord-018142-xt71w4nr	20	5	very	very	RB
cord-018142-xt71w4nr	20	6	low	low	JJ
cord-018142-xt71w4nr	20	7	levels	level	NNS
cord-018142-xt71w4nr	20	8	of	of	IN
cord-018142-xt71w4nr	20	9	ADAMTS-13	adamts-13	ADD
cord-018142-xt71w4nr	20	10	protein	protein	NN
cord-018142-xt71w4nr	20	11	activity	activity	NN
cord-018142-xt71w4nr	20	12	1	1	CD
cord-018142-xt71w4nr	20	13	,	,	,
cord-018142-xt71w4nr	20	14	resulting	result	VBG
cord-018142-xt71w4nr	20	15	in	in	IN
cord-018142-xt71w4nr	20	16	elevated	elevated	JJ
cord-018142-xt71w4nr	20	17	plasma	plasma	NN
cord-018142-xt71w4nr	20	18	levels	level	NNS
cord-018142-xt71w4nr	20	19	of	of	IN
cord-018142-xt71w4nr	20	20	ULvWF	ULvWF	NNP
cord-018142-xt71w4nr	20	21	[	[	-LRB-
cord-018142-xt71w4nr	20	22	5	5	CD
cord-018142-xt71w4nr	20	23	]	]	-RRB-
cord-018142-xt71w4nr	20	24	.	.	.
cord-018142-xt71w4nr	21	1	In	in	IN
cord-018142-xt71w4nr	21	2	this	this	DT
cord-018142-xt71w4nr	21	3	context	context	NN
cord-018142-xt71w4nr	21	4	of	of	IN
cord-018142-xt71w4nr	21	5	metalloprotease	metalloprotease	NNP
cord-018142-xt71w4nr	21	6	deficiency	deficiency	NN
cord-018142-xt71w4nr	21	7	,	,	,
cord-018142-xt71w4nr	21	8	ULvWF	ULvWF	NNP
cord-018142-xt71w4nr	21	9	are	be	VBP
cord-018142-xt71w4nr	21	10	released	release	VBN
cord-018142-xt71w4nr	21	11	in	in	IN
cord-018142-xt71w4nr	21	12	response	response	NN
cord-018142-xt71w4nr	21	13	to	to	IN
cord-018142-xt71w4nr	21	14	endothelial	endothelial	JJ
cord-018142-xt71w4nr	21	15	cell	cell	NN
cord-018142-xt71w4nr	21	16	damage	damage	NN
cord-018142-xt71w4nr	21	17	,	,	,
cord-018142-xt71w4nr	21	18	and	and	CC
cord-018142-xt71w4nr	21	19	then	then	RB
cord-018142-xt71w4nr	21	20	accumulate	accumulate	VB
cord-018142-xt71w4nr	21	21	and	and	CC
cord-018142-xt71w4nr	21	22	adopt	adopt	VB
cord-018142-xt71w4nr	21	23	an	an	DT
cord-018142-xt71w4nr	21	24	optimal	optimal	JJ
cord-018142-xt71w4nr	21	25	procoagulant	procoagulant	NN
cord-018142-xt71w4nr	21	26	configuration	configuration	NN
cord-018142-xt71w4nr	21	27	,	,	,
cord-018142-xt71w4nr	21	28	resistant	resistant	JJ
cord-018142-xt71w4nr	21	29	to	to	IN
cord-018142-xt71w4nr	21	30	the	the	DT
cord-018142-xt71w4nr	21	31	shearing	shearing	NN
cord-018142-xt71w4nr	21	32	forces	force	NNS
cord-018142-xt71w4nr	21	33	of	of	IN
cord-018142-xt71w4nr	21	34	the	the	DT
cord-018142-xt71w4nr	21	35	microcirculation	microcirculation	NN
cord-018142-xt71w4nr	21	36	.	.	.
cord-018142-xt71w4nr	22	1	ULvWF	ULvWF	NNP
cord-018142-xt71w4nr	22	2	bind	bind	VB
cord-018142-xt71w4nr	22	3	to	to	IN
cord-018142-xt71w4nr	22	4	platelet	platelet	NN
cord-018142-xt71w4nr	22	5	GPIIb	GPIIb	NNS
cord-018142-xt71w4nr	22	6	and	and	CC
cord-018142-xt71w4nr	22	7	GPIIb	GPIIb	NNP
cord-018142-xt71w4nr	22	8	/	/	SYM
cord-018142-xt71w4nr	22	9	IIIa	iiia	NN
cord-018142-xt71w4nr	22	10	receptors	receptor	NNS
cord-018142-xt71w4nr	22	11	,	,	,
cord-018142-xt71w4nr	22	12	inducing	induce	VBG
cord-018142-xt71w4nr	22	13	excessive	excessive	JJ
cord-018142-xt71w4nr	22	14	platelet	platelet	NN
cord-018142-xt71w4nr	22	15	aggregation	aggregation	NN
cord-018142-xt71w4nr	22	16	.	.	.
cord-018142-xt71w4nr	23	1	This	this	DT
cord-018142-xt71w4nr	23	2	mechanism	mechanism	NN
cord-018142-xt71w4nr	23	3	is	be	VBZ
cord-018142-xt71w4nr	23	4	responsible	responsible	JJ
cord-018142-xt71w4nr	23	5	for	for	IN
cord-018142-xt71w4nr	23	6	consumption	consumption	NN
cord-018142-xt71w4nr	23	7	thrombocytopenia	thrombocytopenia	NNS
cord-018142-xt71w4nr	23	8	and	and	CC
cord-018142-xt71w4nr	23	9	the	the	DT
cord-018142-xt71w4nr	23	10	formation	formation	NN
cord-018142-xt71w4nr	23	11	of	of	IN
cord-018142-xt71w4nr	23	12	microthrombi	microthrombi	NNP
cord-018142-xt71w4nr	23	13	decreasing	decrease	VBG
cord-018142-xt71w4nr	23	14	the	the	DT
cord-018142-xt71w4nr	23	15	caliber	caliber	NN
cord-018142-xt71w4nr	23	16	of	of	IN
cord-018142-xt71w4nr	23	17	capillaries	capillary	NNS
cord-018142-xt71w4nr	23	18	of	of	IN
cord-018142-xt71w4nr	23	19	the	the	DT
cord-018142-xt71w4nr	23	20	microcirculation	microcirculation	NN
cord-018142-xt71w4nr	23	21	,	,	,
cord-018142-xt71w4nr	23	22	leading	lead	VBG
cord-018142-xt71w4nr	23	23	to	to	IN
cord-018142-xt71w4nr	23	24	tissue	tissue	NN
cord-018142-xt71w4nr	23	25	ischemia	ischemia	NN
cord-018142-xt71w4nr	23	26	and	and	CC
cord-018142-xt71w4nr	23	27	erythrocyte	erythrocyte	NN
cord-018142-xt71w4nr	23	28	fragmentation	fragmentation	NN
cord-018142-xt71w4nr	23	29	on	on	IN
cord-018142-xt71w4nr	23	30	thrombi	thrombi	NNP
cord-018142-xt71w4nr	23	31	(	(	-LRB-
cord-018142-xt71w4nr	23	32	schistocytes	schistocytes	NNP
cord-018142-xt71w4nr	23	33	)	)	-RRB-
cord-018142-xt71w4nr	23	34	[	[	-LRB-
cord-018142-xt71w4nr	23	35	2	2	CD
cord-018142-xt71w4nr	23	36	]	]	-RRB-
cord-018142-xt71w4nr	23	37	.	.	.
cord-018142-xt71w4nr	24	1	Deficiency	deficiency	NN
cord-018142-xt71w4nr	24	2	of	of	IN
cord-018142-xt71w4nr	24	3	the	the	DT
cord-018142-xt71w4nr	24	4	protease	protease	NN
cord-018142-xt71w4nr	24	5	cleaving	cleave	VBG
cord-018142-xt71w4nr	24	6	ULvWF	ULvWF	NNP
cord-018142-xt71w4nr	24	7	in	in	IN
cord-018142-xt71w4nr	24	8	TTP	TTP	NNP
cord-018142-xt71w4nr	24	9	is	be	VBZ
cord-018142-xt71w4nr	24	10	attributed	attribute	VBN
cord-018142-xt71w4nr	24	11	either	either	CC
cord-018142-xt71w4nr	24	12	to	to	IN
cord-018142-xt71w4nr	24	13	acquisition	acquisition	NN
cord-018142-xt71w4nr	24	14	of	of	IN
cord-018142-xt71w4nr	24	15	an	an	DT
cord-018142-xt71w4nr	24	16	IgG	IgG	NNP
cord-018142-xt71w4nr	24	17	inhibitory	inhibitory	JJ
cord-018142-xt71w4nr	24	18	auto	auto	NN
cord-018142-xt71w4nr	24	19	-	-	HYPH
cord-018142-xt71w4nr	24	20	antibody	antibody	NN
cord-018142-xt71w4nr	24	21	or	or	CC
cord-018142-xt71w4nr	24	22	to	to	IN
cord-018142-xt71w4nr	24	23	a	a	DT
cord-018142-xt71w4nr	24	24	mutation	mutation	NN
cord-018142-xt71w4nr	24	25	of	of	IN
cord-018142-xt71w4nr	24	26	the	the	DT
cord-018142-xt71w4nr	24	27	gene	gene	NN
cord-018142-xt71w4nr	24	28	coding	code	VBG
cord-018142-xt71w4nr	24	29	for	for	IN
cord-018142-xt71w4nr	24	30	the	the	DT
cord-018142-xt71w4nr	24	31	protease	protease	NN
cord-018142-xt71w4nr	24	32	(	(	-LRB-
cord-018142-xt71w4nr	24	33	familial	familial	JJ
cord-018142-xt71w4nr	24	34	cases	case	NNS
cord-018142-xt71w4nr	24	35	)	)	-RRB-
cord-018142-xt71w4nr	25	1	[	[	-LRB-
cord-018142-xt71w4nr	25	2	6±10	6±10	NN
cord-018142-xt71w4nr	25	3	]	]	-RRB-
cord-018142-xt71w4nr	25	4	.	.	.
cord-018142-xt71w4nr	26	1	Role	role	NN
cord-018142-xt71w4nr	26	2	of	of	IN
cord-018142-xt71w4nr	26	3	infections	infection	NNS
cord-018142-xt71w4nr	26	4	in	in	IN
cord-018142-xt71w4nr	26	5	the	the	DT
cord-018142-xt71w4nr	26	6	pathogenesis	pathogenesis	NN
cord-018142-xt71w4nr	26	7	of	of	IN
cord-018142-xt71w4nr	26	8	TTP	TTP	NNP
cord-018142-xt71w4nr	26	9	.	.	.
cord-018142-xt71w4nr	27	1	TMA	TMA	NNP
cord-018142-xt71w4nr	27	2	is	be	VBZ
cord-018142-xt71w4nr	27	3	frequently	frequently	RB
cord-018142-xt71w4nr	27	4	associated	associate	VBN
cord-018142-xt71w4nr	27	5	with	with	IN
cord-018142-xt71w4nr	27	6	infection	infection	NN
cord-018142-xt71w4nr	27	7	,	,	,
cord-018142-xt71w4nr	27	8	whether	whether	IN
cord-018142-xt71w4nr	27	9	or	or	CC
cord-018142-xt71w4nr	27	10	not	not	RB
cord-018142-xt71w4nr	27	11	there	there	EX
cord-018142-xt71w4nr	27	12	is	be	VBZ
cord-018142-xt71w4nr	27	13	another	another	DT
cord-018142-xt71w4nr	27	14	underlying	underlie	VBG
cord-018142-xt71w4nr	27	15	disease	disease	NN
cord-018142-xt71w4nr	27	16	[	[	-LRB-
cord-018142-xt71w4nr	27	17	11	11	CD
cord-018142-xt71w4nr	27	18	]	]	-RRB-
cord-018142-xt71w4nr	27	19	.	.	.
cord-018142-xt71w4nr	28	1	In	in	IN
cord-018142-xt71w4nr	28	2	a	a	DT
cord-018142-xt71w4nr	28	3	retrospective	retrospective	JJ
cord-018142-xt71w4nr	28	4	intensive	intensive	JJ
cord-018142-xt71w4nr	28	5	care	care	NN
cord-018142-xt71w4nr	28	6	study	study	NN
cord-018142-xt71w4nr	28	7	,	,	,
cord-018142-xt71w4nr	28	8	53	53	CD
cord-018142-xt71w4nr	28	9	%	%	NN
cord-018142-xt71w4nr	28	10	of	of	IN
cord-018142-xt71w4nr	28	11	cases	case	NNS
cord-018142-xt71w4nr	28	12	of	of	IN
cord-018142-xt71w4nr	28	13	TMA	TMA	NNP
cord-018142-xt71w4nr	28	14	were	be	VBD
cord-018142-xt71w4nr	28	15	associated	associate	VBN
cord-018142-xt71w4nr	28	16	with	with	IN
cord-018142-xt71w4nr	28	17	infection	infection	NN
cord-018142-xt71w4nr	28	18	[	[	-LRB-
cord-018142-xt71w4nr	28	19	1	1	CD
cord-018142-xt71w4nr	28	20	]	]	-RRB-
cord-018142-xt71w4nr	28	21	.	.	.
cord-018142-xt71w4nr	29	1	These	these	DT
cord-018142-xt71w4nr	29	2	infections	infection	NNS
cord-018142-xt71w4nr	29	3	have	have	VBP
cord-018142-xt71w4nr	29	4	a	a	DT
cord-018142-xt71w4nr	29	5	major	major	JJ
cord-018142-xt71w4nr	29	6	impact	impact	NN
cord-018142-xt71w4nr	29	7	on	on	IN
cord-018142-xt71w4nr	29	8	the	the	DT
cord-018142-xt71w4nr	29	9	patient	patient	NN
cord-018142-xt71w4nr	29	10	's	's	POS
cord-018142-xt71w4nr	29	11	outcome	outcome	NN
cord-018142-xt71w4nr	29	12	[	[	-LRB-
cord-018142-xt71w4nr	29	13	11	11	CD
cord-018142-xt71w4nr	29	14	]	]	-RRB-
cord-018142-xt71w4nr	29	15	.	.	.
cord-018142-xt71w4nr	30	1	Various	various	JJ
cord-018142-xt71w4nr	30	2	microorganisms	microorganism	NNS
cord-018142-xt71w4nr	30	3	have	have	VBP
cord-018142-xt71w4nr	30	4	been	be	VBN
cord-018142-xt71w4nr	30	5	isolated	isolate	VBN
cord-018142-xt71w4nr	30	6	during	during	IN
cord-018142-xt71w4nr	30	7	the	the	DT
cord-018142-xt71w4nr	30	8	acute	acute	JJ
cord-018142-xt71w4nr	30	9	phase	phase	NN
cord-018142-xt71w4nr	30	10	of	of	IN
cord-018142-xt71w4nr	30	11	TTP	TTP	NNP
cord-018142-xt71w4nr	30	12	,	,	,
cord-018142-xt71w4nr	30	13	or	or	CC
cord-018142-xt71w4nr	30	14	during	during	IN
cord-018142-xt71w4nr	30	15	the	the	DT
cord-018142-xt71w4nr	30	16	days	day	NNS
cord-018142-xt71w4nr	30	17	preceding	precede	VBG
cord-018142-xt71w4nr	30	18	TTP	TTP	NNP
cord-018142-xt71w4nr	30	19	(	(	-LRB-
cord-018142-xt71w4nr	30	20	Table	table	NN
cord-018142-xt71w4nr	30	21	1	1	CD
cord-018142-xt71w4nr	30	22	[	[	-LRB-
cord-018142-xt71w4nr	30	23	12±20	12±20	NNP
cord-018142-xt71w4nr	30	24	]	]	-RRB-
cord-018142-xt71w4nr	30	25	)	)	-RRB-
cord-018142-xt71w4nr	30	26	.	.	.
cord-018142-xt71w4nr	31	1	An	an	DT
cord-018142-xt71w4nr	31	2	underlying	underlie	VBG
cord-018142-xt71w4nr	31	3	infection	infection	NN
cord-018142-xt71w4nr	31	4	must	must	MD
cord-018142-xt71w4nr	31	5	be	be	VB
cord-018142-xt71w4nr	31	6	systematically	systematically	RB
cord-018142-xt71w4nr	31	7	sought	seek	VBN
cord-018142-xt71w4nr	31	8	in	in	IN
cord-018142-xt71w4nr	31	9	all	all	DT
cord-018142-xt71w4nr	31	10	cases	case	NNS
cord-018142-xt71w4nr	31	11	of	of	IN
cord-018142-xt71w4nr	31	12	TMA	TMA	NNP
cord-018142-xt71w4nr	31	13	.	.	.
cord-018142-xt71w4nr	32	1	The	the	DT
cord-018142-xt71w4nr	32	2	infectious	infectious	JJ
cord-018142-xt71w4nr	32	3	agent	agent	NN
cord-018142-xt71w4nr	32	4	involved	involve	VBN
cord-018142-xt71w4nr	32	5	in	in	IN
cord-018142-xt71w4nr	32	6	the	the	DT
cord-018142-xt71w4nr	32	7	pathogenesis	pathogenesis	NN
cord-018142-xt71w4nr	32	8	of	of	IN
cord-018142-xt71w4nr	32	9	TTP	TTP	NNP
cord-018142-xt71w4nr	32	10	induces	induce	VBZ
cord-018142-xt71w4nr	32	11	a	a	DT
cord-018142-xt71w4nr	32	12	direct	direct	JJ
cord-018142-xt71w4nr	32	13	or	or	CC
cord-018142-xt71w4nr	32	14	indirect	indirect	JJ
cord-018142-xt71w4nr	32	15	endothelial	endothelial	JJ
cord-018142-xt71w4nr	32	16	lesion	lesion	NN
cord-018142-xt71w4nr	32	17	(	(	-LRB-
cord-018142-xt71w4nr	32	18	mediated	mediate	VBN
cord-018142-xt71w4nr	32	19	by	by	IN
cord-018142-xt71w4nr	32	20	sepsis	sepsis	NN
cord-018142-xt71w4nr	32	21	)	)	-RRB-
cord-018142-xt71w4nr	32	22	,	,	,
cord-018142-xt71w4nr	32	23	as	as	IN
cord-018142-xt71w4nr	32	24	various	various	JJ
cord-018142-xt71w4nr	32	25	mediators	mediator	NNS
cord-018142-xt71w4nr	32	26	(	(	-LRB-
cord-018142-xt71w4nr	32	27	interleukin	interleukin	XX
cord-018142-xt71w4nr	32	28	[	[	-LRB-
cord-018142-xt71w4nr	32	29	IL]-1	IL]-1	NNP
cord-018142-xt71w4nr	32	30	and	and	CC
cord-018142-xt71w4nr	32	31	IL-6	IL-6	NNP
cord-018142-xt71w4nr	32	32	,	,	,
cord-018142-xt71w4nr	32	33	interferon	interferon	NN
cord-018142-xt71w4nr	32	34	gamma	gamma	NN
cord-018142-xt71w4nr	32	35	[	[	-LRB-
cord-018142-xt71w4nr	32	36	IFN	IFN	NNP
cord-018142-xt71w4nr	32	37	-	-	HYPH
cord-018142-xt71w4nr	32	38	c	c	NNP
cord-018142-xt71w4nr	32	39	,	,	,
cord-018142-xt71w4nr	32	40	tumor	tumor	NN
cord-018142-xt71w4nr	32	41	necrosis	necrosis	NN
cord-018142-xt71w4nr	32	42	factor	factor	NN
cord-018142-xt71w4nr	32	43	[	[	-LRB-
cord-018142-xt71w4nr	32	44	TNF]-a	tnf]-a	CD
cord-018142-xt71w4nr	32	45	)	)	-RRB-
cord-018142-xt71w4nr	32	46	are	be	VBP
cord-018142-xt71w4nr	32	47	released	release	VBN
cord-018142-xt71w4nr	32	48	during	during	IN
cord-018142-xt71w4nr	32	49	the	the	DT
cord-018142-xt71w4nr	32	50	inflammatory	inflammatory	JJ
cord-018142-xt71w4nr	32	51	reaction	reaction	NN
cord-018142-xt71w4nr	32	52	of	of	IN
cord-018142-xt71w4nr	32	53	sepsis	sepsis	NN
cord-018142-xt71w4nr	32	54	and	and	CC
cord-018142-xt71w4nr	32	55	generate	generate	VBP
cord-018142-xt71w4nr	32	56	endothelial	endothelial	JJ
cord-018142-xt71w4nr	32	57	lesions	lesion	NNS
cord-018142-xt71w4nr	32	58	.	.	.
cord-018142-xt71w4nr	33	1	S.	S.	NNP
cord-018142-xt71w4nr	33	2	Samy	Samy	NNP
cord-018142-xt71w4nr	33	3	Modeliar	Modeliar	NNP
cord-018142-xt71w4nr	33	4	et	et	NNP
cord-018142-xt71w4nr	33	5	al	al	NNP
cord-018142-xt71w4nr	33	6	.	.	.
cord-018142-xt71w4nr	34	1	Damaged	damage	VBN
cord-018142-xt71w4nr	34	2	endothelial	endothelial	JJ
cord-018142-xt71w4nr	34	3	cells	cell	NNS
cord-018142-xt71w4nr	34	4	degranulate	degranulate	NNP
cord-018142-xt71w4nr	34	5	,	,	,
cord-018142-xt71w4nr	34	6	releasing	release	VBG
cord-018142-xt71w4nr	34	7	procoagulant	procoagulant	JJ
cord-018142-xt71w4nr	34	8	substances	substance	NNS
cord-018142-xt71w4nr	34	9	(	(	-LRB-
cord-018142-xt71w4nr	34	10	ULvWF	ULvWF	NNP
cord-018142-xt71w4nr	34	11	,	,	,
cord-018142-xt71w4nr	34	12	platelet	platelet	NN
cord-018142-xt71w4nr	34	13	-	-	HYPH
cord-018142-xt71w4nr	34	14	activating	activate	VBG
cord-018142-xt71w4nr	34	15	factor	factor	NN
cord-018142-xt71w4nr	34	16	[	[	-LRB-
cord-018142-xt71w4nr	34	17	PAF	PAF	NNP
cord-018142-xt71w4nr	34	18	]	]	-RRB-
cord-018142-xt71w4nr	34	19	)	)	-RRB-
cord-018142-xt71w4nr	34	20	into	into	IN
cord-018142-xt71w4nr	34	21	the	the	DT
cord-018142-xt71w4nr	34	22	plasma	plasma	NN
cord-018142-xt71w4nr	34	23	,	,	,
cord-018142-xt71w4nr	34	24	express	express	JJ
cord-018142-xt71w4nr	34	25	adhesion	adhesion	NN
cord-018142-xt71w4nr	34	26	molecules	molecule	NNS
cord-018142-xt71w4nr	34	27	and	and	CC
cord-018142-xt71w4nr	34	28	produce	produce	VBP
cord-018142-xt71w4nr	34	29	chemokines	chemokine	NNS
cord-018142-xt71w4nr	34	30	such	such	JJ
cord-018142-xt71w4nr	34	31	as	as	IN
cord-018142-xt71w4nr	34	32	IL-8	IL-8	NNP
cord-018142-xt71w4nr	34	33	.	.	.
cord-018142-xt71w4nr	35	1	These	these	DT
cord-018142-xt71w4nr	35	2	phenomena	phenomenon	NNS
cord-018142-xt71w4nr	35	3	promote	promote	VBP
cord-018142-xt71w4nr	35	4	adhesion	adhesion	NN
cord-018142-xt71w4nr	35	5	and	and	CC
cord-018142-xt71w4nr	35	6	activation	activation	NN
cord-018142-xt71w4nr	35	7	of	of	IN
cord-018142-xt71w4nr	35	8	neutrophils	neutrophil	NNS
cord-018142-xt71w4nr	35	9	,	,	,
cord-018142-xt71w4nr	35	10	which	which	WDT
cord-018142-xt71w4nr	35	11	participate	participate	VBP
cord-018142-xt71w4nr	35	12	in	in	IN
cord-018142-xt71w4nr	35	13	endothelial	endothelial	JJ
cord-018142-xt71w4nr	35	14	lesions	lesion	NNS
cord-018142-xt71w4nr	35	15	.	.	.
cord-018142-xt71w4nr	36	1	Activated	activate	VBN
cord-018142-xt71w4nr	36	2	endothelial	endothelial	JJ
cord-018142-xt71w4nr	36	3	cells	cell	NNS
cord-018142-xt71w4nr	36	4	also	also	RB
cord-018142-xt71w4nr	36	5	show	show	VBP
cord-018142-xt71w4nr	36	6	decreased	decreased	JJ
cord-018142-xt71w4nr	36	7	synthesis	synthesis	NN
cord-018142-xt71w4nr	36	8	of	of	IN
cord-018142-xt71w4nr	36	9	prostaglandin	prostaglandin	NN
cord-018142-xt71w4nr	36	10	I2	i2	NN
cord-018142-xt71w4nr	36	11	(	(	-LRB-
cord-018142-xt71w4nr	36	12	PGI2	PGI2	NNP
cord-018142-xt71w4nr	36	13	)	)	-RRB-
cord-018142-xt71w4nr	36	14	,	,	,
cord-018142-xt71w4nr	36	15	the	the	DT
cord-018142-xt71w4nr	36	16	most	most	RBS
cord-018142-xt71w4nr	36	17	potent	potent	JJ
cord-018142-xt71w4nr	36	18	platelet	platelet	NN
cord-018142-xt71w4nr	36	19	aggregation	aggregation	NN
cord-018142-xt71w4nr	36	20	inhibitor	inhibitor	NN
cord-018142-xt71w4nr	36	21	in	in	IN
cord-018142-xt71w4nr	36	22	the	the	DT
cord-018142-xt71w4nr	36	23	body	body	NN
cord-018142-xt71w4nr	36	24	.	.	.
cord-018142-xt71w4nr	37	1	These	these	DT
cord-018142-xt71w4nr	37	2	mechanisms	mechanism	NNS
cord-018142-xt71w4nr	37	3	lead	lead	VBP
cord-018142-xt71w4nr	37	4	to	to	IN
cord-018142-xt71w4nr	37	5	a	a	DT
cord-018142-xt71w4nr	37	6	hypercoagulability	hypercoagulability	NN
cord-018142-xt71w4nr	37	7	state	state	NN
cord-018142-xt71w4nr	37	8	,	,	,
cord-018142-xt71w4nr	37	9	which	which	WDT
cord-018142-xt71w4nr	37	10	persists	persist	VBZ
cord-018142-xt71w4nr	37	11	in	in	IN
cord-018142-xt71w4nr	37	12	individuals	individual	NNS
cord-018142-xt71w4nr	37	13	presenting	present	VBG
cord-018142-xt71w4nr	37	14	predisposing	predisposing	JJ
cord-018142-xt71w4nr	37	15	factors	factor	NNS
cord-018142-xt71w4nr	37	16	.	.	.
cord-018142-xt71w4nr	38	1	The	the	DT
cord-018142-xt71w4nr	38	2	pathophysiology	pathophysiology	NN
cord-018142-xt71w4nr	38	3	of	of	IN
cord-018142-xt71w4nr	38	4	HUS	HUS	NNP
cord-018142-xt71w4nr	38	5	is	be	VBZ
cord-018142-xt71w4nr	38	6	characterized	characterize	VBN
cord-018142-xt71w4nr	38	7	by	by	IN
cord-018142-xt71w4nr	38	8	intravascular	intravascular	JJ
cord-018142-xt71w4nr	38	9	coagulation	coagulation	NN
cord-018142-xt71w4nr	38	10	specifically	specifically	RB
cord-018142-xt71w4nr	38	11	involving	involve	VBG
cord-018142-xt71w4nr	38	12	the	the	DT
cord-018142-xt71w4nr	38	13	renal	renal	JJ
cord-018142-xt71w4nr	38	14	microcirculation	microcirculation	NN
cord-018142-xt71w4nr	38	15	.	.	.
cord-018142-xt71w4nr	39	1	Two	two	CD
cord-018142-xt71w4nr	39	2	very	very	RB
cord-018142-xt71w4nr	39	3	different	different	JJ
cord-018142-xt71w4nr	39	4	forms	form	NNS
cord-018142-xt71w4nr	39	5	are	be	VBP
cord-018142-xt71w4nr	39	6	distinguished	distinguish	VBN
cord-018142-xt71w4nr	39	7	:	:	:
cord-018142-xt71w4nr	39	8	z	z	LS
cord-018142-xt71w4nr	39	9	post	post	JJ
cord-018142-xt71w4nr	39	10	-	-	JJ
cord-018142-xt71w4nr	39	11	diarrheal	diarrheal	JJ
cord-018142-xt71w4nr	39	12	HUS	hus	NN
cord-018142-xt71w4nr	39	13	,	,	,
cord-018142-xt71w4nr	39	14	usually	usually	RB
cord-018142-xt71w4nr	39	15	endemic	endemic	JJ
cord-018142-xt71w4nr	39	16	and	and	CC
cord-018142-xt71w4nr	39	17	mainly	mainly	RB
cord-018142-xt71w4nr	39	18	affecting	affect	VBG
cord-018142-xt71w4nr	39	19	young	young	JJ
cord-018142-xt71w4nr	39	20	children	child	NNS
cord-018142-xt71w4nr	39	21	(	(	-LRB-
cord-018142-xt71w4nr	39	22	1±5	1±5	CD
cord-018142-xt71w4nr	39	23	years	year	NNS
cord-018142-xt71w4nr	39	24	)	)	-RRB-
cord-018142-xt71w4nr	39	25	,	,	,
cord-018142-xt71w4nr	39	26	z	z	LS
cord-018142-xt71w4nr	39	27	HUS	HUS	NNP
cord-018142-xt71w4nr	39	28	occurring	occur	VBG
cord-018142-xt71w4nr	39	29	in	in	IN
cord-018142-xt71w4nr	39	30	the	the	DT
cord-018142-xt71w4nr	39	31	absence	absence	NN
cord-018142-xt71w4nr	39	32	of	of	IN
cord-018142-xt71w4nr	39	33	diarrhea	diarrhea	NN
cord-018142-xt71w4nr	39	34	or	or	CC
cord-018142-xt71w4nr	39	35	atypical	atypical	JJ
cord-018142-xt71w4nr	39	36	HUS	HUS	NNP
cord-018142-xt71w4nr	39	37	,	,	,
cord-018142-xt71w4nr	39	38	observed	observe	VBD
cord-018142-xt71w4nr	39	39	in	in	IN
cord-018142-xt71w4nr	39	40	older	old	JJR
cord-018142-xt71w4nr	39	41	children	child	NNS
cord-018142-xt71w4nr	39	42	and	and	CC
cord-018142-xt71w4nr	39	43	adults	adult	NNS
cord-018142-xt71w4nr	39	44	.	.	.
cord-018142-xt71w4nr	40	1	Post	post	JJ
cord-018142-xt71w4nr	40	2	-	-	JJ
cord-018142-xt71w4nr	40	3	diarrheal	diarrheal	JJ
cord-018142-xt71w4nr	40	4	HUS	HUS	NNP
cord-018142-xt71w4nr	40	5	[	[	-LRB-
cord-018142-xt71w4nr	40	6	21	21	CD
cord-018142-xt71w4nr	40	7	]	]	-RRB-
cord-018142-xt71w4nr	40	8	.	.	.
cord-018142-xt71w4nr	41	1	This	this	DT
cord-018142-xt71w4nr	41	2	is	be	VBZ
cord-018142-xt71w4nr	41	3	the	the	DT
cord-018142-xt71w4nr	41	4	most	most	RBS
cord-018142-xt71w4nr	41	5	frequent	frequent	JJ
cord-018142-xt71w4nr	41	6	form	form	NN
cord-018142-xt71w4nr	41	7	of	of	IN
cord-018142-xt71w4nr	41	8	HUS	HUS	NNP
cord-018142-xt71w4nr	41	9	(	(	-LRB-
cord-018142-xt71w4nr	41	10	90	90	CD
cord-018142-xt71w4nr	41	11	%	%	NN
cord-018142-xt71w4nr	41	12	of	of	IN
cord-018142-xt71w4nr	41	13	cases	case	NNS
cord-018142-xt71w4nr	41	14	)	)	-RRB-
cord-018142-xt71w4nr	41	15	.	.	.
cord-018142-xt71w4nr	42	1	The	the	DT
cord-018142-xt71w4nr	42	2	majority	majority	NN
cord-018142-xt71w4nr	42	3	of	of	IN
cord-018142-xt71w4nr	42	4	cases	case	NNS
cord-018142-xt71w4nr	42	5	are	be	VBP
cord-018142-xt71w4nr	42	6	due	due	JJ
cord-018142-xt71w4nr	42	7	to	to	IN
cord-018142-xt71w4nr	42	8	toxin	toxin	NN
cord-018142-xt71w4nr	42	9	-	-	HYPH
cord-018142-xt71w4nr	42	10	producing	produce	VBG
cord-018142-xt71w4nr	42	11	Escherichia	escherichia	NN
cord-018142-xt71w4nr	42	12	coli	coli	NNS
cord-018142-xt71w4nr	42	13	gastrointestinal	gastrointestinal	JJ
cord-018142-xt71w4nr	42	14	infection	infection	NN
cord-018142-xt71w4nr	42	15	.	.	.
cord-018142-xt71w4nr	43	1	The	the	DT
cord-018142-xt71w4nr	43	2	serotype	serotype	NN
cord-018142-xt71w4nr	43	3	most	most	RBS
cord-018142-xt71w4nr	43	4	frequently	frequently	RB
cord-018142-xt71w4nr	43	5	isolated	isolate	VBN
cord-018142-xt71w4nr	43	6	is	be	VBZ
cord-018142-xt71w4nr	43	7	E.	E.	NNP
cord-018142-xt71w4nr	43	8	coli	coli	VBZ
cord-018142-xt71w4nr	43	9	0157	0157	CD
cord-018142-xt71w4nr	43	10	:	:	:
cord-018142-xt71w4nr	44	1	H7	H7	NNP
cord-018142-xt71w4nr	44	2	,	,	,
cord-018142-xt71w4nr	44	3	but	but	CC
cord-018142-xt71w4nr	44	4	many	many	JJ
cord-018142-xt71w4nr	44	5	other	other	JJ
cord-018142-xt71w4nr	44	6	serotypes	serotype	NNS
cord-018142-xt71w4nr	44	7	as	as	RB
cord-018142-xt71w4nr	44	8	well	well	RB
cord-018142-xt71w4nr	44	9	as	as	IN
cord-018142-xt71w4nr	44	10	many	many	JJ
cord-018142-xt71w4nr	44	11	other	other	JJ
cord-018142-xt71w4nr	44	12	bacteria	bacteria	NNS
cord-018142-xt71w4nr	44	13	have	have	VBP
cord-018142-xt71w4nr	44	14	been	be	VBN
cord-018142-xt71w4nr	44	15	incriminated	incriminate	VBN
cord-018142-xt71w4nr	44	16	(	(	-LRB-
cord-018142-xt71w4nr	44	17	Table	table	NN
cord-018142-xt71w4nr	44	18	2	2	CD
cord-018142-xt71w4nr	44	19	)	)	-RRB-
cord-018142-xt71w4nr	44	20	.	.	.
cord-018142-xt71w4nr	45	1	The	the	DT
cord-018142-xt71w4nr	45	2	E.	E.	NNP
cord-018142-xt71w4nr	45	3	coli	coli	NNS
cord-018142-xt71w4nr	45	4	toxin	toxin	NN
cord-018142-xt71w4nr	45	5	is	be	VBZ
cord-018142-xt71w4nr	45	6	called	call	VBN
cord-018142-xt71w4nr	45	7	Shiga	Shiga	NNP
cord-018142-xt71w4nr	45	8	-	-	HYPH
cord-018142-xt71w4nr	45	9	like	like	JJ
cord-018142-xt71w4nr	45	10	-	-	HYPH
cord-018142-xt71w4nr	45	11	toxin	toxin	NN
cord-018142-xt71w4nr	45	12	(	(	-LRB-
cord-018142-xt71w4nr	45	13	SLT	SLT	NNP
cord-018142-xt71w4nr	45	14	)	)	-RRB-
cord-018142-xt71w4nr	45	15	due	due	IN
cord-018142-xt71w4nr	45	16	to	to	IN
cord-018142-xt71w4nr	45	17	its	-PRON-	PRP$
cord-018142-xt71w4nr	45	18	structural	structural	JJ
cord-018142-xt71w4nr	45	19	analogy	analogy	NN
cord-018142-xt71w4nr	45	20	with	with	IN
cord-018142-xt71w4nr	45	21	Shigella	Shigella	NNP
cord-018142-xt71w4nr	45	22	dysenteriae	dysenteriae	NN
cord-018142-xt71w4nr	45	23	toxin	toxin	NN
cord-018142-xt71w4nr	45	24	type	type	NN
cord-018142-xt71w4nr	45	25	1	1	CD
cord-018142-xt71w4nr	45	26	.	.	.
cord-018142-xt71w4nr	46	1	The	the	DT
cord-018142-xt71w4nr	46	2	pathophysiology	pathophysiology	NN
cord-018142-xt71w4nr	46	3	of	of	IN
cord-018142-xt71w4nr	46	4	post	post	JJ
cord-018142-xt71w4nr	46	5	-	-	JJ
cord-018142-xt71w4nr	46	6	diarrheal	diarrheal	JJ
cord-018142-xt71w4nr	46	7	HUS	hus	NN
cord-018142-xt71w4nr	46	8	starts	start	VBZ
cord-018142-xt71w4nr	46	9	with	with	IN
cord-018142-xt71w4nr	46	10	ingestion	ingestion	NN
cord-018142-xt71w4nr	46	11	of	of	IN
cord-018142-xt71w4nr	46	12	food	food	NN
cord-018142-xt71w4nr	46	13	usually	usually	RB
cord-018142-xt71w4nr	46	14	contaminated	contaminate	VBN
cord-018142-xt71w4nr	46	15	by	by	IN
cord-018142-xt71w4nr	46	16	a	a	DT
cord-018142-xt71w4nr	46	17	strain	strain	NN
cord-018142-xt71w4nr	46	18	of	of	IN
cord-018142-xt71w4nr	46	19	toxin	toxin	NN
cord-018142-xt71w4nr	46	20	-	-	HYPH
cord-018142-xt71w4nr	46	21	producing	produce	VBG
cord-018142-xt71w4nr	46	22	E.	E.	NNP
cord-018142-xt71w4nr	46	23	coli	coli	NNS
cord-018142-xt71w4nr	46	24	.	.	.
cord-018142-xt71w4nr	47	1	Intestinal	intestinal	JJ
cord-018142-xt71w4nr	47	2	colonization	colonization	NN
cord-018142-xt71w4nr	47	3	by	by	IN
cord-018142-xt71w4nr	47	4	E.	E.	NNP
cord-018142-xt71w4nr	47	5	coli	coli	NNS
cord-018142-xt71w4nr	47	6	is	be	VBZ
cord-018142-xt71w4nr	47	7	responsible	responsible	JJ
cord-018142-xt71w4nr	47	8	for	for	IN
cord-018142-xt71w4nr	47	9	liquid	liquid	JJ
cord-018142-xt71w4nr	47	10	diarrhea	diarrhea	NN
cord-018142-xt71w4nr	47	11	.	.	.
cord-018142-xt71w4nr	48	1	This	this	DT
cord-018142-xt71w4nr	48	2	colonization	colonization	NN
cord-018142-xt71w4nr	48	3	phase	phase	NN
cord-018142-xt71w4nr	48	4	is	be	VBZ
cord-018142-xt71w4nr	48	5	accompanied	accompany	VBN
cord-018142-xt71w4nr	48	6	by	by	IN
cord-018142-xt71w4nr	48	7	massive	massive	JJ
cord-018142-xt71w4nr	48	8	toxin	toxin	NN
cord-018142-xt71w4nr	48	9	production	production	NN
cord-018142-xt71w4nr	48	10	.	.	.
cord-018142-xt71w4nr	49	1	This	this	DT
cord-018142-xt71w4nr	49	2	toxin	toxin	NN
cord-018142-xt71w4nr	49	3	is	be	VBZ
cord-018142-xt71w4nr	49	4	released	release	VBN
cord-018142-xt71w4nr	49	5	into	into	IN
cord-018142-xt71w4nr	49	6	the	the	DT
cord-018142-xt71w4nr	49	7	intestine	intestine	NN
cord-018142-xt71w4nr	49	8	and	and	CC
cord-018142-xt71w4nr	49	9	is	be	VBZ
cord-018142-xt71w4nr	49	10	responsi	responsi	NN
cord-018142-xt71w4nr	49	11	-	-	HYPH
cord-018142-xt71w4nr	49	12	ble	ble	JJ
cord-018142-xt71w4nr	49	13	for	for	IN
cord-018142-xt71w4nr	49	14	direct	direct	JJ
cord-018142-xt71w4nr	49	15	microvascular	microvascular	JJ
cord-018142-xt71w4nr	49	16	and	and	CC
cord-018142-xt71w4nr	49	17	mucosal	mucosal	JJ
cord-018142-xt71w4nr	49	18	lesions	lesion	NNS
cord-018142-xt71w4nr	49	19	,	,	,
cord-018142-xt71w4nr	49	20	causing	cause	VBG
cord-018142-xt71w4nr	49	21	another	another	DT
cord-018142-xt71w4nr	49	22	episode	episode	NN
cord-018142-xt71w4nr	49	23	of	of	IN
cord-018142-xt71w4nr	49	24	potentially	potentially	RB
cord-018142-xt71w4nr	49	25	hemorrhagic	hemorrhagic	JJ
cord-018142-xt71w4nr	49	26	diarrhea	diarrhea	NN
cord-018142-xt71w4nr	49	27	.	.	.
cord-018142-xt71w4nr	50	1	The	the	DT
cord-018142-xt71w4nr	50	2	toxin	toxin	NN
cord-018142-xt71w4nr	50	3	binds	bind	VBZ
cord-018142-xt71w4nr	50	4	to	to	IN
cord-018142-xt71w4nr	50	5	specific	specific	JJ
cord-018142-xt71w4nr	50	6	receptors	receptor	NNS
cord-018142-xt71w4nr	50	7	,	,	,
cord-018142-xt71w4nr	50	8	is	be	VBZ
cord-018142-xt71w4nr	50	9	internalized	internalize	VBN
cord-018142-xt71w4nr	50	10	and	and	CC
cord-018142-xt71w4nr	50	11	then	then	RB
cord-018142-xt71w4nr	50	12	enters	enter	VBZ
cord-018142-xt71w4nr	50	13	the	the	DT
cord-018142-xt71w4nr	50	14	systemic	systemic	JJ
cord-018142-xt71w4nr	50	15	circulation	circulation	NN
cord-018142-xt71w4nr	50	16	.	.	.
cord-018142-xt71w4nr	51	1	E.	E.	NNP
cord-018142-xt71w4nr	51	2	coli	coli	VBZ
cord-018142-xt71w4nr	51	3	bacteremia	bacteremia	NN
cord-018142-xt71w4nr	51	4	is	be	VBZ
cord-018142-xt71w4nr	51	5	not	not	RB
cord-018142-xt71w4nr	51	6	usually	usually	RB
cord-018142-xt71w4nr	51	7	observed	observe	VBN
cord-018142-xt71w4nr	51	8	in	in	IN
cord-018142-xt71w4nr	51	9	post	post	JJ
cord-018142-xt71w4nr	51	10	-	-	JJ
cord-018142-xt71w4nr	51	11	diarrheal	diarrheal	JJ
cord-018142-xt71w4nr	51	12	HUS	hus	NN
cord-018142-xt71w4nr	51	13	.	.	.
cord-018142-xt71w4nr	52	1	The	the	DT
cord-018142-xt71w4nr	52	2	toxin	toxin	NN
cord-018142-xt71w4nr	52	3	is	be	VBZ
cord-018142-xt71w4nr	52	4	transported	transport	VBN
cord-018142-xt71w4nr	52	5	by	by	IN
cord-018142-xt71w4nr	52	6	neutrophils	neutrophil	NNS
cord-018142-xt71w4nr	52	7	to	to	TO
cord-018142-xt71w4nr	52	8	target	target	VB
cord-018142-xt71w4nr	52	9	tissues	tissue	NNS
cord-018142-xt71w4nr	52	10	,	,	,
cord-018142-xt71w4nr	52	11	i.e.	i.e.	FW
cord-018142-xt71w4nr	52	12	,	,	,
cord-018142-xt71w4nr	52	13	the	the	DT
cord-018142-xt71w4nr	52	14	kidney	kidney	NN
cord-018142-xt71w4nr	52	15	,	,	,
cord-018142-xt71w4nr	52	16	where	where	WRB
cord-018142-xt71w4nr	52	17	it	-PRON-	PRP
cord-018142-xt71w4nr	52	18	binds	bind	VBZ
cord-018142-xt71w4nr	52	19	to	to	IN
cord-018142-xt71w4nr	52	20	specific	specific	JJ
cord-018142-xt71w4nr	52	21	receptors	receptor	NNS
cord-018142-xt71w4nr	52	22	situated	situate	VBN
cord-018142-xt71w4nr	52	23	on	on	IN
cord-018142-xt71w4nr	52	24	endothelial	endothelial	JJ
cord-018142-xt71w4nr	52	25	cells	cell	NNS
cord-018142-xt71w4nr	52	26	of	of	IN
cord-018142-xt71w4nr	52	27	the	the	DT
cord-018142-xt71w4nr	52	28	renal	renal	JJ
cord-018142-xt71w4nr	52	29	cortex	cortex	NN
cord-018142-xt71w4nr	52	30	and	and	CC
cord-018142-xt71w4nr	52	31	medulla	medulla	NN
cord-018142-xt71w4nr	52	32	and	and	CC
cord-018142-xt71w4nr	52	33	tubular	tubular	JJ
cord-018142-xt71w4nr	52	34	epithelial	epithelial	JJ
cord-018142-xt71w4nr	52	35	cells	cell	NNS
cord-018142-xt71w4nr	52	36	.	.	.
cord-018142-xt71w4nr	53	1	It	-PRON-	PRP
cord-018142-xt71w4nr	53	2	is	be	VBZ
cord-018142-xt71w4nr	53	3	internalized	internalize	VBN
cord-018142-xt71w4nr	53	4	in	in	IN
cord-018142-xt71w4nr	53	5	renal	renal	JJ
cord-018142-xt71w4nr	53	6	cells	cell	NNS
cord-018142-xt71w4nr	53	7	and	and	CC
cord-018142-xt71w4nr	53	8	induces	induce	VBZ
cord-018142-xt71w4nr	53	9	inhibition	inhibition	NN
cord-018142-xt71w4nr	53	10	of	of	IN
cord-018142-xt71w4nr	53	11	protein	protein	NN
cord-018142-xt71w4nr	53	12	synthesis	synthesis	NN
cord-018142-xt71w4nr	53	13	via	via	IN
cord-018142-xt71w4nr	53	14	ribosomal	ribosomal	JJ
cord-018142-xt71w4nr	53	15	inactivation	inactivation	NN
cord-018142-xt71w4nr	53	16	(	(	-LRB-
cord-018142-xt71w4nr	53	17	depurinization	depurinization	NN
cord-018142-xt71w4nr	53	18	)	)	-RRB-
cord-018142-xt71w4nr	53	19	,	,	,
cord-018142-xt71w4nr	53	20	leading	lead	VBG
cord-018142-xt71w4nr	53	21	to	to	IN
cord-018142-xt71w4nr	53	22	apoptotic	apoptotic	JJ
cord-018142-xt71w4nr	53	23	cell	cell	NN
cord-018142-xt71w4nr	53	24	death	death	NN
cord-018142-xt71w4nr	53	25	.	.	.
cord-018142-xt71w4nr	54	1	In	in	IN
cord-018142-xt71w4nr	54	2	addition	addition	NN
cord-018142-xt71w4nr	54	3	to	to	IN
cord-018142-xt71w4nr	54	4	these	these	DT
cord-018142-xt71w4nr	54	5	lesions	lesion	NNS
cord-018142-xt71w4nr	54	6	,	,	,
cord-018142-xt71w4nr	54	7	the	the	DT
cord-018142-xt71w4nr	54	8	toxin	toxin	NN
cord-018142-xt71w4nr	54	9	also	also	RB
cord-018142-xt71w4nr	54	10	stimulates	stimulate	VBZ
cord-018142-xt71w4nr	54	11	cytokine	cytokine	NN
cord-018142-xt71w4nr	54	12	production	production	NN
cord-018142-xt71w4nr	54	13	.	.	.
cord-018142-xt71w4nr	55	1	Endothelial	endothelial	JJ
cord-018142-xt71w4nr	55	2	cell	cell	NN
cord-018142-xt71w4nr	55	3	damage	damage	NN
cord-018142-xt71w4nr	55	4	has	have	VBZ
cord-018142-xt71w4nr	55	5	several	several	JJ
cord-018142-xt71w4nr	55	6	consequences	consequence	NNS
cord-018142-xt71w4nr	55	7	:	:	:
cord-018142-xt71w4nr	55	8	expression	expression	NN
cord-018142-xt71w4nr	55	9	of	of	IN
cord-018142-xt71w4nr	55	10	tissue	tissue	NN
cord-018142-xt71w4nr	55	11	factor	factor	NN
cord-018142-xt71w4nr	55	12	on	on	IN
cord-018142-xt71w4nr	55	13	the	the	DT
cord-018142-xt71w4nr	55	14	cell	cell	NN
cord-018142-xt71w4nr	55	15	surface	surface	NN
cord-018142-xt71w4nr	55	16	,	,	,
cord-018142-xt71w4nr	55	17	activation	activation	NN
cord-018142-xt71w4nr	55	18	of	of	IN
cord-018142-xt71w4nr	55	19	coagulation	coagulation	NN
cord-018142-xt71w4nr	55	20	,	,	,
cord-018142-xt71w4nr	55	21	release	release	NN
cord-018142-xt71w4nr	55	22	of	of	IN
cord-018142-xt71w4nr	55	23	PAF	PAF	NNP
cord-018142-xt71w4nr	55	24	into	into	IN
cord-018142-xt71w4nr	55	25	the	the	DT
cord-018142-xt71w4nr	55	26	circulation	circulation	NN
cord-018142-xt71w4nr	55	27	,	,	,
cord-018142-xt71w4nr	55	28	and	and	CC
cord-018142-xt71w4nr	55	29	induction	induction	NN
cord-018142-xt71w4nr	55	30	of	of	IN
cord-018142-xt71w4nr	55	31	overexpression	overexpression	NN
cord-018142-xt71w4nr	55	32	of	of	IN
cord-018142-xt71w4nr	55	33	plasminogen	plasminogen	NN
cord-018142-xt71w4nr	55	34	activator	activator	NN
cord-018142-xt71w4nr	55	35	inhibitor	inhibitor	NN
cord-018142-xt71w4nr	55	36	(	(	-LRB-
cord-018142-xt71w4nr	55	37	PAI)-1	pai)-1	NN
cord-018142-xt71w4nr	55	38	on	on	IN
cord-018142-xt71w4nr	55	39	the	the	DT
cord-018142-xt71w4nr	55	40	endothelial	endothelial	JJ
cord-018142-xt71w4nr	55	41	cell	cell	NN
cord-018142-xt71w4nr	55	42	surface	surface	NN
cord-018142-xt71w4nr	55	43	.	.	.
cord-018142-xt71w4nr	56	1	Damaged	damage	VBN
cord-018142-xt71w4nr	56	2	endothelial	endothelial	JJ
cord-018142-xt71w4nr	56	3	cells	cell	NNS
cord-018142-xt71w4nr	56	4	also	also	RB
cord-018142-xt71w4nr	56	5	show	show	VBP
cord-018142-xt71w4nr	56	6	decreased	decrease	VBD
cord-018142-xt71w4nr	56	7	PGI2	PGI2	NNP
cord-018142-xt71w4nr	56	8	production	production	NN
cord-018142-xt71w4nr	56	9	,	,	,
cord-018142-xt71w4nr	56	10	and	and	CC
cord-018142-xt71w4nr	56	11	activate	activate	VBP
cord-018142-xt71w4nr	56	12	platelets	platelet	NNS
cord-018142-xt71w4nr	56	13	and	and	CC
cord-018142-xt71w4nr	56	14	neutrophils	neutrophil	NNS
cord-018142-xt71w4nr	56	15	predisposing	predispose	VBG
cord-018142-xt71w4nr	56	16	to	to	IN
cord-018142-xt71w4nr	56	17	platelet	platelet	NN
cord-018142-xt71w4nr	56	18	aggregation	aggregation	NN
cord-018142-xt71w4nr	56	19	on	on	IN
cord-018142-xt71w4nr	56	20	the	the	DT
cord-018142-xt71w4nr	56	21	endothelial	endothelial	JJ
cord-018142-xt71w4nr	56	22	cell	cell	NN
cord-018142-xt71w4nr	56	23	surface	surface	NN
cord-018142-xt71w4nr	56	24	.	.	.
cord-018142-xt71w4nr	57	1	These	these	DT
cord-018142-xt71w4nr	57	2	phenomena	phenomenon	NNS
cord-018142-xt71w4nr	57	3	lead	lead	VBP
cord-018142-xt71w4nr	57	4	to	to	IN
cord-018142-xt71w4nr	57	5	the	the	DT
cord-018142-xt71w4nr	57	6	formation	formation	NN
cord-018142-xt71w4nr	57	7	of	of	IN
cord-018142-xt71w4nr	57	8	fibrin	fibrin	NN
cord-018142-xt71w4nr	57	9	-	-	HYPH
cord-018142-xt71w4nr	57	10	rich	rich	JJ
cord-018142-xt71w4nr	57	11	microthrombi	microthrombi	NN
cord-018142-xt71w4nr	57	12	in	in	IN
cord-018142-xt71w4nr	57	13	renal	renal	JJ
cord-018142-xt71w4nr	57	14	capillaries	capillary	NNS
cord-018142-xt71w4nr	57	15	,	,	,
cord-018142-xt71w4nr	57	16	resulting	result	VBG
cord-018142-xt71w4nr	57	17	in	in	IN
cord-018142-xt71w4nr	57	18	renal	renal	JJ
cord-018142-xt71w4nr	57	19	failure	failure	NN
cord-018142-xt71w4nr	57	20	,	,	,
cord-018142-xt71w4nr	57	21	formation	formation	NN
cord-018142-xt71w4nr	57	22	of	of	IN
cord-018142-xt71w4nr	57	23	schistocytes	schistocyte	NNS
cord-018142-xt71w4nr	57	24	and	and	CC
cord-018142-xt71w4nr	57	25	consumption	consumption	NN
cord-018142-xt71w4nr	57	26	thrombocytopenia	thrombocytopenia	NN
cord-018142-xt71w4nr	57	27	.	.	.
cord-018142-xt71w4nr	58	1	Atypical	atypical	JJ
cord-018142-xt71w4nr	58	2	HUS	HUS	NNP
cord-018142-xt71w4nr	58	3	[	[	-LRB-
cord-018142-xt71w4nr	58	4	2	2	CD
cord-018142-xt71w4nr	58	5	,	,	,
cord-018142-xt71w4nr	58	6	22	22	CD
cord-018142-xt71w4nr	58	7	]	]	-RRB-
cord-018142-xt71w4nr	58	8	.	.	.
cord-018142-xt71w4nr	59	1	Atypical	atypical	JJ
cord-018142-xt71w4nr	59	2	HUS	hus	NN
cord-018142-xt71w4nr	59	3	is	be	VBZ
cord-018142-xt71w4nr	59	4	much	much	RB
cord-018142-xt71w4nr	59	5	rarer	rare	JJR
cord-018142-xt71w4nr	59	6	(	(	-LRB-
cord-018142-xt71w4nr	59	7	7	7	CD
cord-018142-xt71w4nr	59	8	to	to	TO
cord-018142-xt71w4nr	59	9	10	10	CD
cord-018142-xt71w4nr	59	10	%	%	NN
cord-018142-xt71w4nr	59	11	of	of	IN
cord-018142-xt71w4nr	59	12	cases	case	NNS
cord-018142-xt71w4nr	59	13	)	)	-RRB-
cord-018142-xt71w4nr	59	14	,	,	,
cord-018142-xt71w4nr	59	15	occurring	occur	VBG
cord-018142-xt71w4nr	59	16	sporadically	sporadically	RB
cord-018142-xt71w4nr	59	17	in	in	IN
cord-018142-xt71w4nr	59	18	adults	adult	NNS
cord-018142-xt71w4nr	59	19	and	and	CC
cord-018142-xt71w4nr	59	20	older	old	JJR
cord-018142-xt71w4nr	59	21	children	child	NNS
cord-018142-xt71w4nr	59	22	.	.	.
cord-018142-xt71w4nr	60	1	It	-PRON-	PRP
cord-018142-xt71w4nr	60	2	is	be	VBZ
cord-018142-xt71w4nr	60	3	characterized	characterize	VBN
cord-018142-xt71w4nr	60	4	by	by	IN
cord-018142-xt71w4nr	60	5	the	the	DT
cord-018142-xt71w4nr	60	6	absence	absence	NN
cord-018142-xt71w4nr	60	7	of	of	IN
cord-018142-xt71w4nr	60	8	gastrointestinal	gastrointestinal	JJ
cord-018142-xt71w4nr	60	9	infection	infection	NN
cord-018142-xt71w4nr	60	10	.	.	.
cord-018142-xt71w4nr	61	1	Its	-PRON-	PRP$
cord-018142-xt71w4nr	61	2	pathophysiology	pathophysiology	NN
cord-018142-xt71w4nr	61	3	is	be	VBZ
cord-018142-xt71w4nr	61	4	poorly	poorly	RB
cord-018142-xt71w4nr	61	5	elucidated	elucidate	VBN
cord-018142-xt71w4nr	61	6	.	.	.
cord-018142-xt71w4nr	62	1	Various	various	JJ
cord-018142-xt71w4nr	62	2	hypotheses	hypothesis	NNS
cord-018142-xt71w4nr	62	3	have	have	VBP
cord-018142-xt71w4nr	62	4	been	be	VBN
cord-018142-xt71w4nr	62	5	proposed	propose	VBN
cord-018142-xt71w4nr	62	6	in	in	IN
cord-018142-xt71w4nr	62	7	adults	adult	NNS
cord-018142-xt71w4nr	62	8	(	(	-LRB-
cord-018142-xt71w4nr	62	9	viral	viral	JJ
cord-018142-xt71w4nr	62	10	infections	infection	NNS
cord-018142-xt71w4nr	62	11	,	,	,
cord-018142-xt71w4nr	62	12	bacterial	bacterial	JJ
cord-018142-xt71w4nr	62	13	infections	infection	NNS
cord-018142-xt71w4nr	62	14	,	,	,
cord-018142-xt71w4nr	62	15	certain	certain	JJ
cord-018142-xt71w4nr	62	16	drugs	drug	NNS
cord-018142-xt71w4nr	62	17	,	,	,
cord-018142-xt71w4nr	62	18	etc	etc	FW
cord-018142-xt71w4nr	62	19	.	.	.
cord-018142-xt71w4nr	62	20	)	)	-RRB-
cord-018142-xt71w4nr	63	1	to	to	TO
cord-018142-xt71w4nr	63	2	be	be	VB
cord-018142-xt71w4nr	63	3	responsible	responsible	JJ
cord-018142-xt71w4nr	63	4	for	for	IN
cord-018142-xt71w4nr	63	5	endothelial	endothelial	JJ
cord-018142-xt71w4nr	63	6	lesions	lesion	NNS
cord-018142-xt71w4nr	63	7	and	and	CC
cord-018142-xt71w4nr	63	8	features	feature	NNS
cord-018142-xt71w4nr	63	9	of	of	IN
cord-018142-xt71w4nr	63	10	HUS	HUS	NNP
cord-018142-xt71w4nr	63	11	.	.	.
cord-018142-xt71w4nr	64	1	A	a	DT
cord-018142-xt71w4nr	64	2	circulating	circulate	VBG
cord-018142-xt71w4nr	64	3	factor	factor	NN
cord-018142-xt71w4nr	64	4	present	present	JJ
cord-018142-xt71w4nr	64	5	in	in	IN
cord-018142-xt71w4nr	64	6	the	the	DT
cord-018142-xt71w4nr	64	7	kidney	kidney	NN
cord-018142-xt71w4nr	64	8	has	have	VBZ
cord-018142-xt71w4nr	64	9	also	also	RB
cord-018142-xt71w4nr	64	10	been	be	VBN
cord-018142-xt71w4nr	64	11	proposed	propose	VBN
cord-018142-xt71w4nr	64	12	.	.	.
cord-018142-xt71w4nr	65	1	Atypical	atypical	JJ
cord-018142-xt71w4nr	65	2	HUS	hus	NN
cord-018142-xt71w4nr	65	3	in	in	IN
cord-018142-xt71w4nr	65	4	children	child	NNS
cord-018142-xt71w4nr	65	5	has	have	VBZ
cord-018142-xt71w4nr	65	6	been	be	VBN
cord-018142-xt71w4nr	65	7	reported	report	VBN
cord-018142-xt71w4nr	65	8	to	to	TO
cord-018142-xt71w4nr	65	9	be	be	VB
cord-018142-xt71w4nr	65	10	associated	associate	VBN
cord-018142-xt71w4nr	65	11	with	with	IN
cord-018142-xt71w4nr	65	12	persistent	persistent	JJ
cord-018142-xt71w4nr	65	13	consumption	consumption	NN
cord-018142-xt71w4nr	65	14	of	of	IN
cord-018142-xt71w4nr	65	15	the	the	DT
cord-018142-xt71w4nr	65	16	C3	c3	JJ
cord-018142-xt71w4nr	65	17	fraction	fraction	NN
cord-018142-xt71w4nr	65	18	of	of	IN
cord-018142-xt71w4nr	65	19	complement	complement	NN
cord-018142-xt71w4nr	65	20	via	via	IN
cord-018142-xt71w4nr	65	21	the	the	DT
cord-018142-xt71w4nr	65	22	alternative	alternative	JJ
cord-018142-xt71w4nr	65	23	pathway	pathway	NN
cord-018142-xt71w4nr	65	24	[	[	-LRB-
cord-018142-xt71w4nr	65	25	23	23	CD
cord-018142-xt71w4nr	65	26	]	]	-RRB-
cord-018142-xt71w4nr	65	27	.	.	.
cord-018142-xt71w4nr	66	1	Decreased	decrease	VBN
cord-018142-xt71w4nr	66	2	complement	complement	NN
cord-018142-xt71w4nr	66	3	levels	level	NNS
cord-018142-xt71w4nr	66	4	can	can	MD
cord-018142-xt71w4nr	66	5	be	be	VB
cord-018142-xt71w4nr	66	6	associated	associate	VBN
cord-018142-xt71w4nr	66	7	with	with	IN
cord-018142-xt71w4nr	66	8	factor	factor	NN
cord-018142-xt71w4nr	66	9	H	h	NN
cord-018142-xt71w4nr	66	10	deficiency	deficiency	NN
cord-018142-xt71w4nr	66	11	(	(	-LRB-
cord-018142-xt71w4nr	66	12	factor	factor	NN
cord-018142-xt71w4nr	66	13	H	H	NNP
cord-018142-xt71w4nr	66	14	inhibits	inhibit	VBZ
cord-018142-xt71w4nr	66	15	the	the	DT
cord-018142-xt71w4nr	66	16	alternative	alternative	JJ
cord-018142-xt71w4nr	66	17	complement	complement	NN
cord-018142-xt71w4nr	66	18	pathway	pathway	NN
cord-018142-xt71w4nr	66	19	)	)	-RRB-
cord-018142-xt71w4nr	66	20	.	.	.
cord-018142-xt71w4nr	67	1	Atypical	atypical	JJ
cord-018142-xt71w4nr	67	2	HUS	hus	NN
cord-018142-xt71w4nr	67	3	with	with	IN
cord-018142-xt71w4nr	67	4	factor	factor	NN
cord-018142-xt71w4nr	67	5	H	h	NN
cord-018142-xt71w4nr	67	6	deficiency	deficiency	NN
cord-018142-xt71w4nr	67	7	usually	usually	RB
cord-018142-xt71w4nr	67	8	corresponds	correspond	VBZ
cord-018142-xt71w4nr	67	9	to	to	IN
cord-018142-xt71w4nr	67	10	sporadic	sporadic	JJ
cord-018142-xt71w4nr	67	11	cases	case	NNS
cord-018142-xt71w4nr	67	12	rather	rather	RB
cord-018142-xt71w4nr	67	13	than	than	IN
cord-018142-xt71w4nr	67	14	familial	familial	JJ
cord-018142-xt71w4nr	67	15	cases	case	NNS
cord-018142-xt71w4nr	67	16	and	and	CC
cord-018142-xt71w4nr	67	17	is	be	VBZ
cord-018142-xt71w4nr	67	18	rare	rare	JJ
cord-018142-xt71w4nr	67	19	in	in	IN
cord-018142-xt71w4nr	67	20	adults	adult	NNS
cord-018142-xt71w4nr	67	21	[	[	-LRB-
cord-018142-xt71w4nr	67	22	24	24	CD
cord-018142-xt71w4nr	67	23	,	,	,
cord-018142-xt71w4nr	67	24	25	25	CD
cord-018142-xt71w4nr	67	25	]	]	-RRB-
cord-018142-xt71w4nr	67	26	.	.	.
cord-018142-xt71w4nr	68	1	There	there	EX
cord-018142-xt71w4nr	68	2	is	be	VBZ
cord-018142-xt71w4nr	68	3	no	no	DT
cord-018142-xt71w4nr	68	4	clearly	clearly	RB
cord-018142-xt71w4nr	68	5	established	establish	VBN
cord-018142-xt71w4nr	68	6	correlation	correlation	NN
cord-018142-xt71w4nr	68	7	between	between	IN
cord-018142-xt71w4nr	68	8	factor	factor	NN
cord-018142-xt71w4nr	68	9	H	H	NNP
cord-018142-xt71w4nr	68	10	deficiency	deficiency	NN
cord-018142-xt71w4nr	68	11	and	and	CC
cord-018142-xt71w4nr	68	12	the	the	DT
cord-018142-xt71w4nr	68	13	development	development	NN
cord-018142-xt71w4nr	68	14	of	of	IN
cord-018142-xt71w4nr	68	15	atypical	atypical	JJ
cord-018142-xt71w4nr	68	16	HUS	HUS	NNP
cord-018142-xt71w4nr	68	17	(	(	-LRB-
cord-018142-xt71w4nr	68	18	factor	factor	NN
cord-018142-xt71w4nr	68	19	H	h	NN
cord-018142-xt71w4nr	68	20	deficiency	deficiency	NN
cord-018142-xt71w4nr	68	21	induces	induce	VBZ
cord-018142-xt71w4nr	68	22	excessive	excessive	JJ
cord-018142-xt71w4nr	68	23	C3	c3	JJ
cord-018142-xt71w4nr	68	24	consumption	consumption	NN
cord-018142-xt71w4nr	68	25	,	,	,
cord-018142-xt71w4nr	68	26	causing	cause	VBG
cord-018142-xt71w4nr	68	27	increased	increase	VBN
cord-018142-xt71w4nr	68	28	activation	activation	NN
cord-018142-xt71w4nr	68	29	of	of	IN
cord-018142-xt71w4nr	68	30	neutrophils	neutrophil	NNS
cord-018142-xt71w4nr	68	31	and	and	CC
cord-018142-xt71w4nr	68	32	excessive	excessive	JJ
cord-018142-xt71w4nr	68	33	platelet	platelet	NN
cord-018142-xt71w4nr	68	34	aggregation	aggregation	NN
cord-018142-xt71w4nr	68	35	)	)	-RRB-
cord-018142-xt71w4nr	68	36	.	.	.
cord-018142-xt71w4nr	68	37	.	.	.
cord-018142-xt71w4nr	69	1	This	this	DT
cord-018142-xt71w4nr	69	2	is	be	VBZ
cord-018142-xt71w4nr	69	3	a	a	DT
cord-018142-xt71w4nr	69	4	particular	particular	JJ
cord-018142-xt71w4nr	69	5	pathophysiological	pathophysiological	JJ
cord-018142-xt71w4nr	69	6	entity	entity	NN
cord-018142-xt71w4nr	69	7	related	relate	VBN
cord-018142-xt71w4nr	69	8	to	to	IN
cord-018142-xt71w4nr	69	9	expression	expression	NN
cord-018142-xt71w4nr	69	10	of	of	IN
cord-018142-xt71w4nr	69	11	the	the	DT
cord-018142-xt71w4nr	69	12	Thomson	Thomson	NNP
cord-018142-xt71w4nr	69	13	Friedenrich	Friedenrich	NNP
cord-018142-xt71w4nr	69	14	antigen	antigen	NN
cord-018142-xt71w4nr	69	15	on	on	IN
cord-018142-xt71w4nr	69	16	the	the	DT
cord-018142-xt71w4nr	69	17	surface	surface	NN
cord-018142-xt71w4nr	69	18	of	of	IN
cord-018142-xt71w4nr	69	19	erythrocytes	erythrocyte	NNS
cord-018142-xt71w4nr	69	20	,	,	,
cord-018142-xt71w4nr	69	21	endothelial	endothelial	JJ
cord-018142-xt71w4nr	69	22	cells	cell	NNS
cord-018142-xt71w4nr	69	23	,	,	,
cord-018142-xt71w4nr	69	24	and	and	CC
cord-018142-xt71w4nr	69	25	glomeruli	glomerulus	NNS
cord-018142-xt71w4nr	69	26	.	.	.
cord-018142-xt71w4nr	70	1	This	this	DT
cord-018142-xt71w4nr	70	2	antigen	antigen	NN
cord-018142-xt71w4nr	70	3	,	,	,
cord-018142-xt71w4nr	70	4	normally	normally	RB
cord-018142-xt71w4nr	70	5	masked	mask	VBN
cord-018142-xt71w4nr	70	6	by	by	IN
cord-018142-xt71w4nr	70	7	sialic	sialic	JJ
cord-018142-xt71w4nr	70	8	acid	acid	NN
cord-018142-xt71w4nr	70	9	,	,	,
cord-018142-xt71w4nr	70	10	is	be	VBZ
cord-018142-xt71w4nr	70	11	revealed	reveal	VBN
cord-018142-xt71w4nr	70	12	by	by	IN
cord-018142-xt71w4nr	70	13	neuraminidase	neuraminidase	RB
cord-018142-xt71w4nr	70	14	secreted	secrete	VBN
cord-018142-xt71w4nr	70	15	by	by	IN
cord-018142-xt71w4nr	70	16	Pneumococcus	Pneumococcus	NNP
cord-018142-xt71w4nr	70	17	.	.	.
cord-018142-xt71w4nr	71	1	This	this	DT
cord-018142-xt71w4nr	71	2	antigen	antigen	NN
cord-018142-xt71w4nr	71	3	is	be	VBZ
cord-018142-xt71w4nr	71	4	then	then	RB
cord-018142-xt71w4nr	71	5	recognized	recognize	VBN
cord-018142-xt71w4nr	71	6	by	by	IN
cord-018142-xt71w4nr	71	7	circulating	circulate	VBG
cord-018142-xt71w4nr	71	8	IgM	IgM	NNP
cord-018142-xt71w4nr	71	9	,	,	,
cord-018142-xt71w4nr	71	10	leading	lead	VBG
cord-018142-xt71w4nr	71	11	to	to	IN
cord-018142-xt71w4nr	71	12	platelet	platelet	NN
cord-018142-xt71w4nr	71	13	aggregation	aggregation	NN
cord-018142-xt71w4nr	71	14	and	and	CC
cord-018142-xt71w4nr	71	15	endothelial	endothelial	JJ
cord-018142-xt71w4nr	71	16	and	and	CC
cord-018142-xt71w4nr	71	17	glomerular	glomerular	JJ
cord-018142-xt71w4nr	71	18	lesions	lesion	NNS
cord-018142-xt71w4nr	71	19	.	.	.
cord-018142-xt71w4nr	72	1	z	z	LS
cord-018142-xt71w4nr	72	2	Diagnosis	Diagnosis	NNP
cord-018142-xt71w4nr	72	3	TMA	TMA	NNP
cord-018142-xt71w4nr	72	4	disorders	disorder	NNS
cord-018142-xt71w4nr	72	5	are	be	VBP
cord-018142-xt71w4nr	72	6	rare	rare	JJ
cord-018142-xt71w4nr	72	7	in	in	IN
cord-018142-xt71w4nr	72	8	intensive	intensive	JJ
cord-018142-xt71w4nr	72	9	care	care	NN
cord-018142-xt71w4nr	72	10	,	,	,
cord-018142-xt71w4nr	72	11	with	with	IN
cord-018142-xt71w4nr	72	12	a	a	DT
cord-018142-xt71w4nr	72	13	prevalence	prevalence	NN
cord-018142-xt71w4nr	72	14	of	of	IN
cord-018142-xt71w4nr	72	15	0.35	0.35	CD
cord-018142-xt71w4nr	72	16	%	%	NN
cord-018142-xt71w4nr	72	17	of	of	IN
cord-018142-xt71w4nr	72	18	admissions	admission	NNS
cord-018142-xt71w4nr	72	19	according	accord	VBG
cord-018142-xt71w4nr	72	20	to	to	IN
cord-018142-xt71w4nr	72	21	a	a	DT
cord-018142-xt71w4nr	72	22	retrospective	retrospective	JJ
cord-018142-xt71w4nr	72	23	study	study	NN
cord-018142-xt71w4nr	72	24	conducted	conduct	VBN
cord-018142-xt71w4nr	72	25	in	in	IN
cord-018142-xt71w4nr	72	26	adult	adult	NN
cord-018142-xt71w4nr	72	27	intensive	intensive	JJ
cord-018142-xt71w4nr	72	28	care	care	NN
cord-018142-xt71w4nr	72	29	units	unit	NNS
cord-018142-xt71w4nr	72	30	between	between	IN
cord-018142-xt71w4nr	72	31	1998	1998	CD
cord-018142-xt71w4nr	72	32	and	and	CC
cord-018142-xt71w4nr	72	33	2001	2001	CD
cord-018142-xt71w4nr	72	34	(	(	-LRB-
cord-018142-xt71w4nr	72	35	64	64	CD
cord-018142-xt71w4nr	72	36	patients	patient	NNS
cord-018142-xt71w4nr	72	37	)	)	-RRB-
cord-018142-xt71w4nr	72	38	[	[	-LRB-
cord-018142-xt71w4nr	72	39	11	11	CD
cord-018142-xt71w4nr	72	40	]	]	-RRB-
cord-018142-xt71w4nr	72	41	.	.	.
cord-018142-xt71w4nr	73	1	They	-PRON-	PRP
cord-018142-xt71w4nr	73	2	represent	represent	VBP
cord-018142-xt71w4nr	73	3	1	1	CD
cord-018142-xt71w4nr	73	4	in	in	IN
cord-018142-xt71w4nr	73	5	300	300	CD
cord-018142-xt71w4nr	73	6	admissions	admission	NNS
cord-018142-xt71w4nr	73	7	,	,	,
cord-018142-xt71w4nr	73	8	including	include	VBG
cord-018142-xt71w4nr	73	9	cases	case	NNS
cord-018142-xt71w4nr	73	10	of	of	IN
cord-018142-xt71w4nr	73	11	pre	pre	JJ
cord-018142-xt71w4nr	73	12	-	-	JJ
cord-018142-xt71w4nr	73	13	eclampsia	eclampsia	JJ
cord-018142-xt71w4nr	73	14	,	,	,
cord-018142-xt71w4nr	73	15	stem	stem	NN
cord-018142-xt71w4nr	73	16	cell	cell	NN
cord-018142-xt71w4nr	73	17	transplantation	transplantation	NN
cord-018142-xt71w4nr	73	18	,	,	,
cord-018142-xt71w4nr	73	19	HELLP	HELLP	NNP
cord-018142-xt71w4nr	73	20	syndrome	syndrome	NN
cord-018142-xt71w4nr	73	21	and	and	CC
cord-018142-xt71w4nr	73	22	terminal	terminal	JJ
cord-018142-xt71w4nr	73	23	cancer	cancer	NN
cord-018142-xt71w4nr	73	24	.	.	.
cord-018142-xt71w4nr	74	1	Early	early	JJ
cord-018142-xt71w4nr	74	2	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	74	3	is	be	VBZ
cord-018142-xt71w4nr	74	4	important	important	JJ
cord-018142-xt71w4nr	74	5	(	(	-LRB-
cord-018142-xt71w4nr	74	6	the	the	DT
cord-018142-xt71w4nr	74	7	prognosis	prognosis	NN
cord-018142-xt71w4nr	74	8	is	be	VBZ
cord-018142-xt71w4nr	74	9	better	well	JJR
cord-018142-xt71w4nr	74	10	when	when	WRB
cord-018142-xt71w4nr	74	11	appropriate	appropriate	JJ
cord-018142-xt71w4nr	74	12	treatment	treatment	NN
cord-018142-xt71w4nr	74	13	is	be	VBZ
cord-018142-xt71w4nr	74	14	rapidly	rapidly	RB
cord-018142-xt71w4nr	74	15	initiated	initiate	VBN
cord-018142-xt71w4nr	74	16	)	)	-RRB-
cord-018142-xt71w4nr	74	17	.	.	.
cord-018142-xt71w4nr	75	1	A	a	DT
cord-018142-xt71w4nr	75	2	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	75	3	of	of	IN
cord-018142-xt71w4nr	75	4	TMA	TMA	NNP
cord-018142-xt71w4nr	75	5	must	must	MD
cord-018142-xt71w4nr	75	6	be	be	VB
cord-018142-xt71w4nr	75	7	considered	consider	VBN
cord-018142-xt71w4nr	75	8	in	in	IN
cord-018142-xt71w4nr	75	9	any	any	DT
cord-018142-xt71w4nr	75	10	case	case	NN
cord-018142-xt71w4nr	75	11	of	of	IN
cord-018142-xt71w4nr	75	12	sudden	sudden	JJ
cord-018142-xt71w4nr	75	13	onset	onset	NN
cord-018142-xt71w4nr	75	14	of	of	IN
cord-018142-xt71w4nr	75	15	poorly	poorly	RB
cord-018142-xt71w4nr	75	16	defined	define	VBN
cord-018142-xt71w4nr	75	17	neurological	neurological	JJ
cord-018142-xt71w4nr	75	18	symptoms	symptom	NNS
cord-018142-xt71w4nr	75	19	and	and	CC
cord-018142-xt71w4nr	75	20	hematological	hematological	JJ
cord-018142-xt71w4nr	75	21	abnormalities	abnormality	NNS
cord-018142-xt71w4nr	75	22	(	(	-LRB-
cord-018142-xt71w4nr	75	23	especially	especially	RB
cord-018142-xt71w4nr	75	24	thrombocytopenia	thrombocytopenia	NN
cord-018142-xt71w4nr	75	25	and	and	CC
cord-018142-xt71w4nr	75	26	anemia	anemia	NN
cord-018142-xt71w4nr	75	27	)	)	-RRB-
cord-018142-xt71w4nr	75	28	.	.	.
cord-018142-xt71w4nr	76	1	TMA	TMA	NNP
cord-018142-xt71w4nr	76	2	is	be	VBZ
cord-018142-xt71w4nr	76	3	observed	observe	VBN
cord-018142-xt71w4nr	76	4	in	in	IN
cord-018142-xt71w4nr	76	5	severely	severely	RB
cord-018142-xt71w4nr	76	6	ill	ill	JJ
cord-018142-xt71w4nr	76	7	patients	patient	NNS
cord-018142-xt71w4nr	76	8	,	,	,
cord-018142-xt71w4nr	76	9	often	often	RB
cord-018142-xt71w4nr	76	10	requiring	require	VBG
cord-018142-xt71w4nr	76	11	admission	admission	NN
cord-018142-xt71w4nr	76	12	to	to	IN
cord-018142-xt71w4nr	76	13	the	the	DT
cord-018142-xt71w4nr	76	14	ICU	ICU	NNP
cord-018142-xt71w4nr	76	15	.	.	.
cord-018142-xt71w4nr	77	1	In	in	IN
cord-018142-xt71w4nr	77	2	a	a	DT
cord-018142-xt71w4nr	77	3	retrospective	retrospective	JJ
cord-018142-xt71w4nr	77	4	study	study	NN
cord-018142-xt71w4nr	77	5	of	of	IN
cord-018142-xt71w4nr	77	6	TMA	TMA	NNP
cord-018142-xt71w4nr	77	7	in	in	IN
cord-018142-xt71w4nr	77	8	63	63	CD
cord-018142-xt71w4nr	77	9	adult	adult	NN
cord-018142-xt71w4nr	77	10	ICU	ICU	NNP
cord-018142-xt71w4nr	77	11	patients	patient	NNS
cord-018142-xt71w4nr	77	12	conducted	conduct	VBN
cord-018142-xt71w4nr	77	13	in	in	IN
cord-018142-xt71w4nr	77	14	14	14	CD
cord-018142-xt71w4nr	77	15	French	french	JJ
cord-018142-xt71w4nr	77	16	teaching	teaching	NN
cord-018142-xt71w4nr	77	17	hospitals	hospital	NNS
cord-018142-xt71w4nr	77	18	,	,	,
cord-018142-xt71w4nr	77	19	the	the	DT
cord-018142-xt71w4nr	77	20	mean	mean	JJ
cord-018142-xt71w4nr	77	21	simplified	simplified	JJ
cord-018142-xt71w4nr	77	22	acute	acute	JJ
cord-018142-xt71w4nr	77	23	physiology	physiology	NN
cord-018142-xt71w4nr	77	24	score	score	NN
cord-018142-xt71w4nr	77	25	(	(	-LRB-
cord-018142-xt71w4nr	77	26	SAPS	SAPS	NNP
cord-018142-xt71w4nr	77	27	)	)	-RRB-
cord-018142-xt71w4nr	77	28	II	II	NNP
cord-018142-xt71w4nr	77	29	on	on	IN
cord-018142-xt71w4nr	77	30	admission	admission	NN
cord-018142-xt71w4nr	77	31	was	be	VBD
cord-018142-xt71w4nr	77	32	45	45	CD
cord-018142-xt71w4nr	77	33	Ô	ô	NN
cord-018142-xt71w4nr	77	34	26	26	CD
cord-018142-xt71w4nr	77	35	[	[	-LRB-
cord-018142-xt71w4nr	77	36	11	11	CD
cord-018142-xt71w4nr	77	37	]	]	-RRB-
cord-018142-xt71w4nr	77	38	.	.	.
cord-018142-xt71w4nr	78	1	In	in	IN
cord-018142-xt71w4nr	78	2	another	another	DT
cord-018142-xt71w4nr	78	3	retrospective	retrospective	JJ
cord-018142-xt71w4nr	78	4	study	study	NN
cord-018142-xt71w4nr	78	5	,	,	,
cord-018142-xt71w4nr	78	6	the	the	DT
cord-018142-xt71w4nr	78	7	mean	mean	JJ
cord-018142-xt71w4nr	78	8	SAPS	SAPS	NNP
cord-018142-xt71w4nr	78	9	II	II	NNP
cord-018142-xt71w4nr	78	10	score	score	NN
cord-018142-xt71w4nr	78	11	on	on	IN
cord-018142-xt71w4nr	78	12	admission	admission	NN
cord-018142-xt71w4nr	78	13	was	be	VBD
cord-018142-xt71w4nr	78	14	37	37	CD
cord-018142-xt71w4nr	78	15	Ô	ô	NN
cord-018142-xt71w4nr	78	16	18	18	CD
cord-018142-xt71w4nr	78	17	(	(	-LRB-
cord-018142-xt71w4nr	78	18	30	30	CD
cord-018142-xt71w4nr	78	19	patients	patient	NNS
cord-018142-xt71w4nr	78	20	)	)	-RRB-
cord-018142-xt71w4nr	78	21	[	[	-LRB-
cord-018142-xt71w4nr	78	22	1	1	CD
cord-018142-xt71w4nr	78	23	]	]	-RRB-
cord-018142-xt71w4nr	78	24	.	.	.
cord-018142-xt71w4nr	79	1	The	the	DT
cord-018142-xt71w4nr	79	2	criteria	criterion	NNS
cord-018142-xt71w4nr	79	3	for	for	IN
cord-018142-xt71w4nr	79	4	admission	admission	NN
cord-018142-xt71w4nr	79	5	to	to	IN
cord-018142-xt71w4nr	79	6	the	the	DT
cord-018142-xt71w4nr	79	7	ICU	ICU	NNP
cord-018142-xt71w4nr	79	8	are	be	VBP
cord-018142-xt71w4nr	79	9	mainly	mainly	RB
cord-018142-xt71w4nr	79	10	life	life	NN
cord-018142-xt71w4nr	79	11	-	-	HYPH
cord-018142-xt71w4nr	79	12	threatening	threaten	VBG
cord-018142-xt71w4nr	79	13	disease	disease	NN
cord-018142-xt71w4nr	79	14	due	due	IN
cord-018142-xt71w4nr	79	15	to	to	IN
cord-018142-xt71w4nr	79	16	renal	renal	JJ
cord-018142-xt71w4nr	79	17	failure	failure	NN
cord-018142-xt71w4nr	79	18	and/or	and/or	CC
cord-018142-xt71w4nr	79	19	neurological	neurological	JJ
cord-018142-xt71w4nr	79	20	signs	sign	NNS
cord-018142-xt71w4nr	79	21	(	(	-LRB-
cord-018142-xt71w4nr	79	22	convulsions	convulsion	NNS
cord-018142-xt71w4nr	79	23	,	,	,
cord-018142-xt71w4nr	79	24	ischemia	ischemia	NN
cord-018142-xt71w4nr	79	25	,	,	,
cord-018142-xt71w4nr	79	26	coma	coma	NN
cord-018142-xt71w4nr	79	27	)	)	-RRB-
cord-018142-xt71w4nr	79	28	.	.	.
cord-018142-xt71w4nr	80	1	The	the	DT
cord-018142-xt71w4nr	80	2	other	other	JJ
cord-018142-xt71w4nr	80	3	reasons	reason	NNS
cord-018142-xt71w4nr	80	4	for	for	IN
cord-018142-xt71w4nr	80	5	admission	admission	NN
cord-018142-xt71w4nr	80	6	are	be	VBP
cord-018142-xt71w4nr	80	7	hemorrhage	hemorrhage	NN
cord-018142-xt71w4nr	80	8	,	,	,
cord-018142-xt71w4nr	80	9	metabolic	metabolic	JJ
cord-018142-xt71w4nr	80	10	disorders	disorder	NNS
cord-018142-xt71w4nr	80	11	(	(	-LRB-
cord-018142-xt71w4nr	80	12	hepatocellular	hepatocellular	JJ
cord-018142-xt71w4nr	80	13	insufficiency	insufficiency	NN
cord-018142-xt71w4nr	80	14	)	)	-RRB-
cord-018142-xt71w4nr	80	15	,	,	,
cord-018142-xt71w4nr	80	16	arrhythmias	arrhythmia	NNS
cord-018142-xt71w4nr	80	17	,	,	,
cord-018142-xt71w4nr	80	18	myocardial	myocardial	JJ
cord-018142-xt71w4nr	80	19	infarction	infarction	NN
cord-018142-xt71w4nr	80	20	,	,	,
cord-018142-xt71w4nr	80	21	etc	etc	FW
cord-018142-xt71w4nr	80	22	[	[	-LRB-
cord-018142-xt71w4nr	80	23	26	26	CD
cord-018142-xt71w4nr	80	24	]	]	-RRB-
cord-018142-xt71w4nr	80	25	.	.	.
cord-018142-xt71w4nr	81	1	Clinical	clinical	JJ
cord-018142-xt71w4nr	81	2	features	feature	NNS
cord-018142-xt71w4nr	81	3	of	of	IN
cord-018142-xt71w4nr	81	4	TTP	TTP	NNP
cord-018142-xt71w4nr	81	5	[	[	-LRB-
cord-018142-xt71w4nr	81	6	2	2	CD
cord-018142-xt71w4nr	81	7	,	,	,
cord-018142-xt71w4nr	81	8	27	27	CD
cord-018142-xt71w4nr	81	9	]	]	-RRB-
cord-018142-xt71w4nr	82	1	The	the	DT
cord-018142-xt71w4nr	82	2	clinical	clinical	JJ
cord-018142-xt71w4nr	82	3	presentation	presentation	NN
cord-018142-xt71w4nr	82	4	of	of	IN
cord-018142-xt71w4nr	82	5	TTP	TTP	NNP
cord-018142-xt71w4nr	82	6	is	be	VBZ
cord-018142-xt71w4nr	82	7	marked	mark	VBN
cord-018142-xt71w4nr	82	8	by	by	IN
cord-018142-xt71w4nr	82	9	a	a	DT
cord-018142-xt71w4nr	82	10	sudden	sudden	JJ
cord-018142-xt71w4nr	82	11	onset	onset	NN
cord-018142-xt71w4nr	82	12	in	in	IN
cord-018142-xt71w4nr	82	13	an	an	DT
cord-018142-xt71w4nr	82	14	adult	adult	NN
cord-018142-xt71w4nr	82	15	in	in	IN
cord-018142-xt71w4nr	82	16	previously	previously	RB
cord-018142-xt71w4nr	82	17	good	good	JJ
cord-018142-xt71w4nr	82	18	health	health	NN
cord-018142-xt71w4nr	82	19	.	.	.
cord-018142-xt71w4nr	83	1	It	-PRON-	PRP
cord-018142-xt71w4nr	83	2	has	have	VBZ
cord-018142-xt71w4nr	83	3	a	a	DT
cord-018142-xt71w4nr	83	4	female	female	JJ
cord-018142-xt71w4nr	83	5	predominance	predominance	NN
cord-018142-xt71w4nr	83	6	(	(	-LRB-
cord-018142-xt71w4nr	83	7	M	M	NNP
cord-018142-xt71w4nr	83	8	/	/	SYM
cord-018142-xt71w4nr	83	9	F	F	NNP
cord-018142-xt71w4nr	83	10	ratio	ratio	NN
cord-018142-xt71w4nr	83	11	:	:	:
cord-018142-xt71w4nr	83	12	3/2	3/2	LS
cord-018142-xt71w4nr	83	13	)	)	-RRB-
cord-018142-xt71w4nr	83	14	and	and	CC
cord-018142-xt71w4nr	83	15	generally	generally	RB
cord-018142-xt71w4nr	83	16	occurs	occur	VBZ
cord-018142-xt71w4nr	83	17	in	in	IN
cord-018142-xt71w4nr	83	18	the	the	DT
cord-018142-xt71w4nr	83	19	4th	4th	JJ
cord-018142-xt71w4nr	83	20	decade	decade	NN
cord-018142-xt71w4nr	83	21	.	.	.
cord-018142-xt71w4nr	84	1	However	however	RB
cord-018142-xt71w4nr	84	2	,	,	,
cord-018142-xt71w4nr	84	3	it	-PRON-	PRP
cord-018142-xt71w4nr	84	4	can	can	MD
cord-018142-xt71w4nr	84	5	also	also	RB
cord-018142-xt71w4nr	84	6	occur	occur	VB
cord-018142-xt71w4nr	84	7	in	in	IN
cord-018142-xt71w4nr	84	8	older	old	JJR
cord-018142-xt71w4nr	84	9	or	or	CC
cord-018142-xt71w4nr	84	10	younger	young	JJR
cord-018142-xt71w4nr	84	11	people	people	NNS
cord-018142-xt71w4nr	84	12	.	.	.
cord-018142-xt71w4nr	85	1	The	the	DT
cord-018142-xt71w4nr	85	2	estimated	estimate	VBN
cord-018142-xt71w4nr	85	3	incidence	incidence	NN
cord-018142-xt71w4nr	85	4	is	be	VBZ
cord-018142-xt71w4nr	85	5	4	4	CD
cord-018142-xt71w4nr	85	6	per	per	IN
cord-018142-xt71w4nr	85	7	million	million	CD
cord-018142-xt71w4nr	85	8	inhabitants	inhabitant	NNS
cord-018142-xt71w4nr	85	9	per	per	IN
cord-018142-xt71w4nr	85	10	year	year	NN
cord-018142-xt71w4nr	85	11	and	and	CC
cord-018142-xt71w4nr	85	12	has	have	VBZ
cord-018142-xt71w4nr	85	13	been	be	VBN
cord-018142-xt71w4nr	85	14	constantly	constantly	RB
cord-018142-xt71w4nr	85	15	increasing	increase	VBG
cord-018142-xt71w4nr	85	16	over	over	IN
cord-018142-xt71w4nr	85	17	recent	recent	JJ
cord-018142-xt71w4nr	85	18	years	year	NNS
cord-018142-xt71w4nr	85	19	.	.	.
cord-018142-xt71w4nr	86	1	In	in	IN
cord-018142-xt71w4nr	86	2	40	40	CD
cord-018142-xt71w4nr	86	3	%	%	NN
cord-018142-xt71w4nr	86	4	of	of	IN
cord-018142-xt71w4nr	86	5	cases	case	NNS
cord-018142-xt71w4nr	86	6	,	,	,
cord-018142-xt71w4nr	86	7	there	there	EX
cord-018142-xt71w4nr	86	8	is	be	VBZ
cord-018142-xt71w4nr	86	9	a	a	DT
cord-018142-xt71w4nr	86	10	prodromal	prodromal	JJ
cord-018142-xt71w4nr	86	11	phase	phase	NN
cord-018142-xt71w4nr	86	12	resembling	resemble	VBG
cord-018142-xt71w4nr	86	13	viral	viral	JJ
cord-018142-xt71w4nr	86	14	infection	infection	NN
cord-018142-xt71w4nr	86	15	for	for	IN
cord-018142-xt71w4nr	86	16	several	several	JJ
cord-018142-xt71w4nr	86	17	days	day	NNS
cord-018142-xt71w4nr	86	18	before	before	IN
cord-018142-xt71w4nr	86	19	the	the	DT
cord-018142-xt71w4nr	86	20	acute	acute	JJ
cord-018142-xt71w4nr	86	21	episode	episode	NN
cord-018142-xt71w4nr	86	22	(	(	-LRB-
cord-018142-xt71w4nr	86	23	asthenia	asthenia	NNP
cord-018142-xt71w4nr	86	24	,	,	,
cord-018142-xt71w4nr	86	25	arthralgia	arthralgia	NNP
cord-018142-xt71w4nr	86	26	,	,	,
cord-018142-xt71w4nr	86	27	myalgia	myalgia	NNP
cord-018142-xt71w4nr	86	28	,	,	,
cord-018142-xt71w4nr	86	29	low	low	JJ
cord-018142-xt71w4nr	86	30	back	back	RB
cord-018142-xt71w4nr	86	31	and	and	CC
cord-018142-xt71w4nr	86	32	abdominal	abdominal	JJ
cord-018142-xt71w4nr	86	33	pain	pain	NN
cord-018142-xt71w4nr	86	34	)	)	-RRB-
cord-018142-xt71w4nr	86	35	.	.	.
cord-018142-xt71w4nr	87	1	In	in	IN
cord-018142-xt71w4nr	87	2	80	80	CD
cord-018142-xt71w4nr	87	3	%	%	NN
cord-018142-xt71w4nr	87	4	of	of	IN
cord-018142-xt71w4nr	87	5	cases	case	NNS
cord-018142-xt71w4nr	87	6	,	,	,
cord-018142-xt71w4nr	87	7	the	the	DT
cord-018142-xt71w4nr	87	8	triad	triad	NN
cord-018142-xt71w4nr	87	9	suggestive	suggestive	JJ
cord-018142-xt71w4nr	87	10	of	of	IN
cord-018142-xt71w4nr	87	11	the	the	DT
cord-018142-xt71w4nr	87	12	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	87	13	is	be	VBZ
cord-018142-xt71w4nr	87	14	observed	observe	VBN
cord-018142-xt71w4nr	87	15	immediately	immediately	RB
cord-018142-xt71w4nr	87	16	(	(	-LRB-
cord-018142-xt71w4nr	87	17	mechanical	mechanical	JJ
cord-018142-xt71w4nr	87	18	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	87	19	anemia	anemia	NN
cord-018142-xt71w4nr	87	20	,	,	,
cord-018142-xt71w4nr	87	21	peripheral	peripheral	JJ
cord-018142-xt71w4nr	87	22	thrombocytopenia	thrombocytopenia	NNS
cord-018142-xt71w4nr	87	23	and	and	CC
cord-018142-xt71w4nr	87	24	neurological	neurological	JJ
cord-018142-xt71w4nr	87	25	signs	sign	NNS
cord-018142-xt71w4nr	87	26	)	)	-RRB-
cord-018142-xt71w4nr	87	27	.	.	.
cord-018142-xt71w4nr	88	1	In	in	IN
cord-018142-xt71w4nr	88	2	40	40	CD
cord-018142-xt71w4nr	88	3	%	%	NN
cord-018142-xt71w4nr	88	4	of	of	IN
cord-018142-xt71w4nr	88	5	cases	case	NNS
cord-018142-xt71w4nr	88	6	,	,	,
cord-018142-xt71w4nr	88	7	two	two	CD
cord-018142-xt71w4nr	88	8	other	other	JJ
cord-018142-xt71w4nr	88	9	cardinal	cardinal	JJ
cord-018142-xt71w4nr	88	10	signs	sign	NNS
cord-018142-xt71w4nr	88	11	are	be	VBP
cord-018142-xt71w4nr	88	12	present	present	JJ
cord-018142-xt71w4nr	88	13	(	(	-LRB-
cord-018142-xt71w4nr	88	14	hyperthermia	hyperthermia	NN
cord-018142-xt71w4nr	88	15	and	and	CC
cord-018142-xt71w4nr	88	16	renal	renal	JJ
cord-018142-xt71w4nr	88	17	failure	failure	NN
cord-018142-xt71w4nr	88	18	)	)	-RRB-
cord-018142-xt71w4nr	88	19	.	.	.
cord-018142-xt71w4nr	89	1	The	the	DT
cord-018142-xt71w4nr	89	2	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	89	3	of	of	IN
cord-018142-xt71w4nr	89	4	TTP	TTP	NNP
cord-018142-xt71w4nr	89	5	must	must	MD
cord-018142-xt71w4nr	89	6	always	always	RB
cord-018142-xt71w4nr	89	7	be	be	VB
cord-018142-xt71w4nr	89	8	considered	consider	VBN
cord-018142-xt71w4nr	89	9	in	in	IN
cord-018142-xt71w4nr	89	10	a	a	DT
cord-018142-xt71w4nr	89	11	patient	patient	NN
cord-018142-xt71w4nr	89	12	with	with	IN
cord-018142-xt71w4nr	89	13	anemia	anemia	NN
cord-018142-xt71w4nr	89	14	and	and	CC
cord-018142-xt71w4nr	89	15	thrombocytopenia	thrombocytopenia	NN
cord-018142-xt71w4nr	89	16	associated	associate	VBN
cord-018142-xt71w4nr	89	17	with	with	IN
cord-018142-xt71w4nr	89	18	organ	organ	NN
cord-018142-xt71w4nr	89	19	failure	failure	NN
cord-018142-xt71w4nr	89	20	.	.	.
cord-018142-xt71w4nr	90	1	Anemia	anemia	NN
cord-018142-xt71w4nr	90	2	is	be	VBZ
cord-018142-xt71w4nr	90	3	the	the	DT
cord-018142-xt71w4nr	90	4	most	most	RBS
cord-018142-xt71w4nr	90	5	constant	constant	JJ
cord-018142-xt71w4nr	90	6	and	and	CC
cord-018142-xt71w4nr	90	7	earliest	early	JJS
cord-018142-xt71w4nr	90	8	feature	feature	NN
cord-018142-xt71w4nr	90	9	and	and	CC
cord-018142-xt71w4nr	90	10	consists	consist	VBZ
cord-018142-xt71w4nr	90	11	of	of	IN
cord-018142-xt71w4nr	90	12	severe	severe	JJ
cord-018142-xt71w4nr	90	13	,	,	,
cord-018142-xt71w4nr	90	14	regenerating	regenerate	VBG
cord-018142-xt71w4nr	90	15	(	(	-LRB-
cord-018142-xt71w4nr	90	16	reticulocytes	reticulocyte	NNS
cord-018142-xt71w4nr	90	17	>	>	NFP
cord-018142-xt71w4nr	90	18	120,000	120,000	CD
cord-018142-xt71w4nr	90	19	mm	mm	CD
cord-018142-xt71w4nr	90	20	3	3	CD
cord-018142-xt71w4nr	90	21	)	)	-RRB-
cord-018142-xt71w4nr	90	22	,	,	,
cord-018142-xt71w4nr	90	23	normochromic	normochromic	NNP
cord-018142-xt71w4nr	90	24	,	,	,
cord-018142-xt71w4nr	90	25	normocytic	normocytic	JJ
cord-018142-xt71w4nr	90	26	,	,	,
cord-018142-xt71w4nr	90	27	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	90	28	(	(	-LRB-
cord-018142-xt71w4nr	90	29	elevated	elevated	JJ
cord-018142-xt71w4nr	90	30	lactate	lactate	NN
cord-018142-xt71w4nr	90	31	dehydrogenase	dehydrogenase	NN
cord-018142-xt71w4nr	90	32	[	[	-LRB-
cord-018142-xt71w4nr	90	33	LDH	LDH	NNP
cord-018142-xt71w4nr	90	34	]	]	-RRB-
cord-018142-xt71w4nr	90	35	and	and	CC
cord-018142-xt71w4nr	90	36	bilirubin	bilirubin	NN
cord-018142-xt71w4nr	90	37	,	,	,
cord-018142-xt71w4nr	90	38	and	and	CC
cord-018142-xt71w4nr	90	39	very	very	RB
cord-018142-xt71w4nr	90	40	low	low	JJ
cord-018142-xt71w4nr	90	41	haptoglobin	haptoglobin	NN
cord-018142-xt71w4nr	90	42	)	)	-RRB-
cord-018142-xt71w4nr	90	43	,	,	,
cord-018142-xt71w4nr	90	44	microangiopathic	microangiopathic	JJ
cord-018142-xt71w4nr	90	45	anemia	anemia	NN
cord-018142-xt71w4nr	90	46	.	.	.
cord-018142-xt71w4nr	91	1	The	the	DT
cord-018142-xt71w4nr	91	2	blood	blood	NN
cord-018142-xt71w4nr	91	3	smear	smear	NN
cord-018142-xt71w4nr	91	4	reveals	reveal	VBZ
cord-018142-xt71w4nr	91	5	schistocytes	schistocyte	NNS
cord-018142-xt71w4nr	91	6	,	,	,
cord-018142-xt71w4nr	91	7	confirming	confirm	VBG
cord-018142-xt71w4nr	91	8	the	the	DT
cord-018142-xt71w4nr	91	9	mechanical	mechanical	JJ
cord-018142-xt71w4nr	91	10	hemolysis	hemolysis	NN
cord-018142-xt71w4nr	91	11	(	(	-LRB-
cord-018142-xt71w4nr	91	12	negative	negative	JJ
cord-018142-xt71w4nr	91	13	direct	direct	JJ
cord-018142-xt71w4nr	91	14	Coombs	Coombs	NNP
cord-018142-xt71w4nr	91	15	test	test	NN
cord-018142-xt71w4nr	91	16	)	)	-RRB-
cord-018142-xt71w4nr	91	17	.	.	.
cord-018142-xt71w4nr	92	1	The	the	DT
cord-018142-xt71w4nr	92	2	presence	presence	NN
cord-018142-xt71w4nr	92	3	of	of	IN
cord-018142-xt71w4nr	92	4	schistocytes	schistocyte	NNS
cord-018142-xt71w4nr	92	5	may	may	MD
cord-018142-xt71w4nr	92	6	be	be	VB
cord-018142-xt71w4nr	92	7	delayed	delay	VBN
cord-018142-xt71w4nr	92	8	and	and	CC
cord-018142-xt71w4nr	92	9	should	should	MD
cord-018142-xt71w4nr	92	10	be	be	VB
cord-018142-xt71w4nr	92	11	looked	look	VBN
cord-018142-xt71w4nr	92	12	for	for	IN
cord-018142-xt71w4nr	92	13	on	on	IN
cord-018142-xt71w4nr	92	14	subsequent	subsequent	JJ
cord-018142-xt71w4nr	92	15	smears	smear	NNS
cord-018142-xt71w4nr	92	16	[	[	-LRB-
cord-018142-xt71w4nr	92	17	28	28	CD
cord-018142-xt71w4nr	92	18	]	]	-RRB-
cord-018142-xt71w4nr	92	19	.	.	.
cord-018142-xt71w4nr	93	1	Peripheral	peripheral	JJ
cord-018142-xt71w4nr	93	2	thrombocytopenia	thrombocytopenia	NN
cord-018142-xt71w4nr	93	3	is	be	VBZ
cord-018142-xt71w4nr	93	4	marked	mark	VBN
cord-018142-xt71w4nr	93	5	(	(	-LRB-
cord-018142-xt71w4nr	93	6	often	often	RB
cord-018142-xt71w4nr	93	7	less	less	JJR
cord-018142-xt71w4nr	93	8	than	than	IN
cord-018142-xt71w4nr	93	9	20,000	20,000	CD
cord-018142-xt71w4nr	93	10	/	/	SYM
cord-018142-xt71w4nr	93	11	mm	mm	NN
cord-018142-xt71w4nr	93	12	3	3	CD
cord-018142-xt71w4nr	93	13	)	)	-RRB-
cord-018142-xt71w4nr	93	14	and	and	CC
cord-018142-xt71w4nr	93	15	constant	constant	JJ
cord-018142-xt71w4nr	93	16	and	and	CC
cord-018142-xt71w4nr	93	17	reflects	reflect	VBZ
cord-018142-xt71w4nr	93	18	disseminated	disseminate	VBN
cord-018142-xt71w4nr	93	19	intravascular	intravascular	JJ
cord-018142-xt71w4nr	93	20	platelet	platelet	NN
cord-018142-xt71w4nr	93	21	hyperaggregability	hyperaggregability	NN
cord-018142-xt71w4nr	93	22	.	.	.
cord-018142-xt71w4nr	94	1	The	the	DT
cord-018142-xt71w4nr	94	2	hemorrhagic	hemorrhagic	JJ
cord-018142-xt71w4nr	94	3	manifestations	manifestation	NNS
cord-018142-xt71w4nr	94	4	related	relate	VBN
cord-018142-xt71w4nr	94	5	to	to	IN
cord-018142-xt71w4nr	94	6	this	this	DT
cord-018142-xt71w4nr	94	7	thrombocytopenia	thrombocytopenia	NN
cord-018142-xt71w4nr	94	8	are	be	VBP
cord-018142-xt71w4nr	94	9	varied	varied	JJ
cord-018142-xt71w4nr	94	10	in	in	IN
cord-018142-xt71w4nr	94	11	terms	term	NNS
cord-018142-xt71w4nr	94	12	of	of	IN
cord-018142-xt71w4nr	94	13	site	site	NN
cord-018142-xt71w4nr	94	14	and	and	CC
cord-018142-xt71w4nr	94	15	severity	severity	NN
cord-018142-xt71w4nr	94	16	.	.	.
cord-018142-xt71w4nr	95	1	Clotting	clotting	NN
cord-018142-xt71w4nr	95	2	tests	test	NNS
cord-018142-xt71w4nr	95	3	are	be	VBP
cord-018142-xt71w4nr	95	4	normal	normal	JJ
cord-018142-xt71w4nr	95	5	.	.	.
cord-018142-xt71w4nr	96	1	Fibrin	fibrin	NN
cord-018142-xt71w4nr	96	2	and	and	CC
cord-018142-xt71w4nr	96	3	fibrinogen	fibrinogen	NN
cord-018142-xt71w4nr	96	4	degradation	degradation	NN
cord-018142-xt71w4nr	96	5	products	product	NNS
cord-018142-xt71w4nr	96	6	(	(	-LRB-
cord-018142-xt71w4nr	96	7	FDP	FDP	NNP
cord-018142-xt71w4nr	96	8	)	)	-RRB-
cord-018142-xt71w4nr	96	9	may	may	MD
cord-018142-xt71w4nr	96	10	be	be	VB
cord-018142-xt71w4nr	96	11	observed	observe	VBN
cord-018142-xt71w4nr	96	12	in	in	IN
cord-018142-xt71w4nr	96	13	rare	rare	JJ
cord-018142-xt71w4nr	96	14	cases	case	NNS
cord-018142-xt71w4nr	96	15	.	.	.
cord-018142-xt71w4nr	97	1	Neurological	neurological	JJ
cord-018142-xt71w4nr	97	2	signs	sign	NNS
cord-018142-xt71w4nr	97	3	are	be	VBP
cord-018142-xt71w4nr	97	4	present	present	JJ
cord-018142-xt71w4nr	97	5	in	in	IN
cord-018142-xt71w4nr	97	6	only	only	RB
cord-018142-xt71w4nr	97	7	60	60	CD
cord-018142-xt71w4nr	97	8	%	%	NN
cord-018142-xt71w4nr	97	9	of	of	IN
cord-018142-xt71w4nr	97	10	cases	case	NNS
cord-018142-xt71w4nr	97	11	at	at	IN
cord-018142-xt71w4nr	97	12	the	the	DT
cord-018142-xt71w4nr	97	13	initial	initial	JJ
cord-018142-xt71w4nr	97	14	phase	phase	NN
cord-018142-xt71w4nr	97	15	of	of	IN
cord-018142-xt71w4nr	97	16	the	the	DT
cord-018142-xt71w4nr	97	17	disease	disease	NN
cord-018142-xt71w4nr	97	18	(	(	-LRB-
cord-018142-xt71w4nr	97	19	and	and	CC
cord-018142-xt71w4nr	97	20	globally	globally	RB
cord-018142-xt71w4nr	97	21	in	in	IN
cord-018142-xt71w4nr	97	22	84	84	CD
cord-018142-xt71w4nr	97	23	to	to	TO
cord-018142-xt71w4nr	97	24	92	92	CD
cord-018142-xt71w4nr	97	25	%	%	NN
cord-018142-xt71w4nr	97	26	of	of	IN
cord-018142-xt71w4nr	97	27	cases	case	NNS
cord-018142-xt71w4nr	97	28	during	during	IN
cord-018142-xt71w4nr	97	29	the	the	DT
cord-018142-xt71w4nr	97	30	course	course	NN
cord-018142-xt71w4nr	97	31	of	of	IN
cord-018142-xt71w4nr	97	32	the	the	DT
cord-018142-xt71w4nr	97	33	disease	disease	NN
cord-018142-xt71w4nr	97	34	)	)	-RRB-
cord-018142-xt71w4nr	97	35	.	.	.
cord-018142-xt71w4nr	98	1	They	-PRON-	PRP
cord-018142-xt71w4nr	98	2	are	be	VBP
cord-018142-xt71w4nr	98	3	characterized	characterize	VBN
cord-018142-xt71w4nr	98	4	by	by	IN
cord-018142-xt71w4nr	98	5	their	-PRON-	PRP$
cord-018142-xt71w4nr	98	6	sudden	sudden	JJ
cord-018142-xt71w4nr	98	7	onset	onset	NN
cord-018142-xt71w4nr	98	8	and	and	CC
cord-018142-xt71w4nr	98	9	transient	transient	JJ
cord-018142-xt71w4nr	98	10	nature	nature	NN
cord-018142-xt71w4nr	98	11	,	,	,
cord-018142-xt71w4nr	98	12	and	and	CC
cord-018142-xt71w4nr	98	13	intermittent	intermittent	JJ
cord-018142-xt71w4nr	98	14	involvement	involvement	NN
cord-018142-xt71w4nr	98	15	of	of	IN
cord-018142-xt71w4nr	98	16	various	various	JJ
cord-018142-xt71w4nr	98	17	territories	territory	NNS
cord-018142-xt71w4nr	98	18	over	over	IN
cord-018142-xt71w4nr	98	19	an	an	DT
cord-018142-xt71w4nr	98	20	interval	interval	NN
cord-018142-xt71w4nr	98	21	of	of	IN
cord-018142-xt71w4nr	98	22	several	several	JJ
cord-018142-xt71w4nr	98	23	hours	hour	NNS
cord-018142-xt71w4nr	98	24	.	.	.
cord-018142-xt71w4nr	99	1	Neurological	neurological	JJ
cord-018142-xt71w4nr	99	2	signs	sign	NNS
cord-018142-xt71w4nr	99	3	comprise	comprise	VBP
cord-018142-xt71w4nr	99	4	:	:	:
cord-018142-xt71w4nr	99	5	obtundation	obtundation	NN
cord-018142-xt71w4nr	99	6	,	,	,
cord-018142-xt71w4nr	99	7	confusion	confusion	NN
cord-018142-xt71w4nr	99	8	,	,	,
cord-018142-xt71w4nr	99	9	hemiparesis	hemiparesis	NN
cord-018142-xt71w4nr	99	10	,	,	,
cord-018142-xt71w4nr	99	11	dysarthria	dysarthria	NN
cord-018142-xt71w4nr	99	12	,	,	,
cord-018142-xt71w4nr	99	13	aphasia	aphasia	NNP
cord-018142-xt71w4nr	99	14	,	,	,
cord-018142-xt71w4nr	99	15	coma	coma	NN
cord-018142-xt71w4nr	99	16	,	,	,
cord-018142-xt71w4nr	99	17	disorders	disorder	NNS
cord-018142-xt71w4nr	99	18	of	of	IN
cord-018142-xt71w4nr	99	19	consciousness	consciousness	NN
cord-018142-xt71w4nr	99	20	,	,	,
cord-018142-xt71w4nr	99	21	sensory	sensory	JJ
cord-018142-xt71w4nr	99	22	deficit	deficit	NN
cord-018142-xt71w4nr	99	23	.	.	.
cord-018142-xt71w4nr	100	1	Deep	deep	JJ
cord-018142-xt71w4nr	100	2	tendon	tendon	NN
cord-018142-xt71w4nr	100	3	reflexes	reflex	NNS
cord-018142-xt71w4nr	100	4	are	be	VBP
cord-018142-xt71w4nr	100	5	often	often	RB
cord-018142-xt71w4nr	100	6	brisk	brisk	JJ
cord-018142-xt71w4nr	100	7	.	.	.
cord-018142-xt71w4nr	101	1	Generalized	generalized	JJ
cord-018142-xt71w4nr	101	2	convulsions	convulsion	NNS
cord-018142-xt71w4nr	101	3	are	be	VBP
cord-018142-xt71w4nr	101	4	observed	observe	VBN
cord-018142-xt71w4nr	101	5	in	in	IN
cord-018142-xt71w4nr	101	6	20	20	CD
cord-018142-xt71w4nr	101	7	%	%	NN
cord-018142-xt71w4nr	101	8	of	of	IN
cord-018142-xt71w4nr	101	9	cases	case	NNS
cord-018142-xt71w4nr	101	10	and	and	CC
cord-018142-xt71w4nr	101	11	can	can	MD
cord-018142-xt71w4nr	101	12	evolve	evolve	VB
cord-018142-xt71w4nr	101	13	to	to	TO
cord-018142-xt71w4nr	101	14	status	status	NN
cord-018142-xt71w4nr	101	15	epilepticus	epilepticus	NN
cord-018142-xt71w4nr	101	16	.	.	.
cord-018142-xt71w4nr	102	1	Hyperthermia	hyperthermia	NN
cord-018142-xt71w4nr	102	2	is	be	VBZ
cord-018142-xt71w4nr	102	3	present	present	JJ
cord-018142-xt71w4nr	102	4	in	in	IN
cord-018142-xt71w4nr	102	5	20	20	CD
cord-018142-xt71w4nr	102	6	%	%	NN
cord-018142-xt71w4nr	102	7	of	of	IN
cord-018142-xt71w4nr	102	8	cases	case	NNS
cord-018142-xt71w4nr	102	9	at	at	IN
cord-018142-xt71w4nr	102	10	the	the	DT
cord-018142-xt71w4nr	102	11	initial	initial	JJ
cord-018142-xt71w4nr	102	12	phase	phase	NN
cord-018142-xt71w4nr	102	13	,	,	,
cord-018142-xt71w4nr	102	14	and	and	CC
cord-018142-xt71w4nr	102	15	then	then	RB
cord-018142-xt71w4nr	102	16	in	in	IN
cord-018142-xt71w4nr	102	17	59	59	CD
cord-018142-xt71w4nr	102	18	to	to	TO
cord-018142-xt71w4nr	102	19	89	89	CD
cord-018142-xt71w4nr	102	20	%	%	NN
cord-018142-xt71w4nr	102	21	of	of	IN
cord-018142-xt71w4nr	102	22	cases	case	NNS
cord-018142-xt71w4nr	102	23	during	during	IN
cord-018142-xt71w4nr	102	24	the	the	DT
cord-018142-xt71w4nr	102	25	course	course	NN
cord-018142-xt71w4nr	102	26	of	of	IN
cord-018142-xt71w4nr	102	27	the	the	DT
cord-018142-xt71w4nr	102	28	disease	disease	NN
cord-018142-xt71w4nr	102	29	.	.	.
cord-018142-xt71w4nr	103	1	It	-PRON-	PRP
cord-018142-xt71w4nr	103	2	is	be	VBZ
cord-018142-xt71w4nr	103	3	usually	usually	RB
cord-018142-xt71w4nr	103	4	only	only	RB
cord-018142-xt71w4nr	103	5	low	low	JJ
cord-018142-xt71w4nr	103	6	-	-	HYPH
cord-018142-xt71w4nr	103	7	grade	grade	NN
cord-018142-xt71w4nr	103	8	and	and	CC
cord-018142-xt71w4nr	103	9	reflects	reflect	VBZ
cord-018142-xt71w4nr	103	10	underlying	underlie	VBG
cord-018142-xt71w4nr	103	11	hemolysis	hemolysis	NN
cord-018142-xt71w4nr	103	12	and	and	CC
cord-018142-xt71w4nr	103	13	cellular	cellular	JJ
cord-018142-xt71w4nr	103	14	ischemia	ischemia	NN
cord-018142-xt71w4nr	103	15	.	.	.
cord-018142-xt71w4nr	104	1	Renal	renal	JJ
cord-018142-xt71w4nr	104	2	failure	failure	NN
cord-018142-xt71w4nr	104	3	occurs	occur	VBZ
cord-018142-xt71w4nr	104	4	in	in	IN
cord-018142-xt71w4nr	104	5	one	one	CD
cord-018142-xt71w4nr	104	6	half	half	NN
cord-018142-xt71w4nr	104	7	of	of	IN
cord-018142-xt71w4nr	104	8	cases	case	NNS
cord-018142-xt71w4nr	104	9	.	.	.
cord-018142-xt71w4nr	105	1	It	-PRON-	PRP
cord-018142-xt71w4nr	105	2	is	be	VBZ
cord-018142-xt71w4nr	105	3	usually	usually	RB
cord-018142-xt71w4nr	105	4	moderate	moderate	JJ
cord-018142-xt71w4nr	105	5	and	and	CC
cord-018142-xt71w4nr	105	6	,	,	,
cord-018142-xt71w4nr	105	7	in	in	IN
cord-018142-xt71w4nr	105	8	the	the	DT
cord-018142-xt71w4nr	105	9	majority	majority	NN
cord-018142-xt71w4nr	105	10	of	of	IN
cord-018142-xt71w4nr	105	11	cases	case	NNS
cord-018142-xt71w4nr	105	12	,	,	,
cord-018142-xt71w4nr	105	13	consists	consist	VBZ
cord-018142-xt71w4nr	105	14	of	of	IN
cord-018142-xt71w4nr	105	15	macroscopic	macroscopic	JJ
cord-018142-xt71w4nr	105	16	hematuria	hematuria	NN
cord-018142-xt71w4nr	105	17	or	or	CC
cord-018142-xt71w4nr	105	18	slight	slight	JJ
cord-018142-xt71w4nr	105	19	proteinuria	proteinuria	NN
cord-018142-xt71w4nr	105	20	(	(	-LRB-
cord-018142-xt71w4nr	105	21	less	less	JJR
cord-018142-xt71w4nr	105	22	than	than	IN
cord-018142-xt71w4nr	105	23	3	3	CD
cord-018142-xt71w4nr	105	24	g/24	g/24	NN
cord-018142-xt71w4nr	105	25	h	h	NN
cord-018142-xt71w4nr	105	26	)	)	-RRB-
cord-018142-xt71w4nr	105	27	.	.	.
cord-018142-xt71w4nr	106	1	Oligo	Oligo	NNP
cord-018142-xt71w4nr	106	2	-	-	HYPH
cord-018142-xt71w4nr	106	3	anuric	anuric	JJ
cord-018142-xt71w4nr	106	4	renal	renal	JJ
cord-018142-xt71w4nr	106	5	failure	failure	NN
cord-018142-xt71w4nr	106	6	is	be	VBZ
cord-018142-xt71w4nr	106	7	rare	rare	JJ
cord-018142-xt71w4nr	106	8	.	.	.
cord-018142-xt71w4nr	107	1	Other	other	JJ
cord-018142-xt71w4nr	107	2	organ	organ	NN
cord-018142-xt71w4nr	107	3	lesions	lesion	NNS
cord-018142-xt71w4nr	107	4	may	may	MD
cord-018142-xt71w4nr	107	5	be	be	VB
cord-018142-xt71w4nr	107	6	observed	observe	VBN
cord-018142-xt71w4nr	107	7	,	,	,
cord-018142-xt71w4nr	107	8	particularly	particularly	RB
cord-018142-xt71w4nr	107	9	myocardial	myocardial	JJ
cord-018142-xt71w4nr	107	10	infarction	infarction	NN
cord-018142-xt71w4nr	107	11	or	or	CC
cord-018142-xt71w4nr	107	12	myocarditis	myocarditis	NN
cord-018142-xt71w4nr	107	13	that	that	WDT
cord-018142-xt71w4nr	107	14	may	may	MD
cord-018142-xt71w4nr	107	15	lead	lead	VB
cord-018142-xt71w4nr	107	16	to	to	IN
cord-018142-xt71w4nr	107	17	acute	acute	JJ
cord-018142-xt71w4nr	107	18	cardiogenic	cardiogenic	JJ
cord-018142-xt71w4nr	107	19	shock	shock	NN
cord-018142-xt71w4nr	107	20	and	and	CC
cord-018142-xt71w4nr	107	21	chronic	chronic	JJ
cord-018142-xt71w4nr	107	22	heart	heart	NN
cord-018142-xt71w4nr	107	23	failure	failure	NN
cord-018142-xt71w4nr	107	24	.	.	.
cord-018142-xt71w4nr	108	1	Acute	acute	JJ
cord-018142-xt71w4nr	108	2	respiratory	respiratory	JJ
cord-018142-xt71w4nr	108	3	distress	distress	NN
cord-018142-xt71w4nr	108	4	syndrome	syndrome	NN
cord-018142-xt71w4nr	108	5	(	(	-LRB-
cord-018142-xt71w4nr	108	6	ARDS	ARDS	NNP
cord-018142-xt71w4nr	108	7	)	)	-RRB-
cord-018142-xt71w4nr	108	8	requiring	require	VBG
cord-018142-xt71w4nr	108	9	mechanical	mechanical	JJ
cord-018142-xt71w4nr	108	10	ventilation	ventilation	NN
cord-018142-xt71w4nr	108	11	,	,	,
cord-018142-xt71w4nr	108	12	colonic	colonic	JJ
cord-018142-xt71w4nr	108	13	ischemic	ischemic	JJ
cord-018142-xt71w4nr	108	14	,	,	,
cord-018142-xt71w4nr	108	15	acute	acute	JJ
cord-018142-xt71w4nr	108	16	pancreatitis	pancreatitis	NN
cord-018142-xt71w4nr	108	17	and	and	CC
cord-018142-xt71w4nr	108	18	sometimes	sometimes	RB
cord-018142-xt71w4nr	108	19	ocular	ocular	JJ
cord-018142-xt71w4nr	108	20	lesions	lesion	NNS
cord-018142-xt71w4nr	108	21	may	may	MD
cord-018142-xt71w4nr	108	22	also	also	RB
cord-018142-xt71w4nr	108	23	be	be	VB
cord-018142-xt71w4nr	108	24	observed	observe	VBN
cord-018142-xt71w4nr	108	25	.	.	.
cord-018142-xt71w4nr	109	1	Sporadic	sporadic	JJ
cord-018142-xt71w4nr	109	2	TTP	TTP	NNP
cord-018142-xt71w4nr	109	3	that	that	WDT
cord-018142-xt71w4nr	109	4	resolves	resolve	VBZ
cord-018142-xt71w4nr	109	5	definitively	definitively	RB
cord-018142-xt71w4nr	109	6	is	be	VBZ
cord-018142-xt71w4nr	109	7	distinguished	distinguish	VBN
cord-018142-xt71w4nr	109	8	from	from	IN
cord-018142-xt71w4nr	109	9	recurrent	recurrent	JJ
cord-018142-xt71w4nr	109	10	forms	form	NNS
cord-018142-xt71w4nr	109	11	with	with	IN
cord-018142-xt71w4nr	109	12	regular	regular	JJ
cord-018142-xt71w4nr	109	13	and	and	CC
cord-018142-xt71w4nr	109	14	frequent	frequent	JJ
cord-018142-xt71w4nr	109	15	relapses	relapse	NNS
cord-018142-xt71w4nr	109	16	,	,	,
cord-018142-xt71w4nr	109	17	and	and	CC
cord-018142-xt71w4nr	109	18	intermittent	intermittent	JJ
cord-018142-xt71w4nr	109	19	TTP	ttp	NN
cord-018142-xt71w4nr	109	20	associated	associate	VBN
cord-018142-xt71w4nr	109	21	with	with	IN
cord-018142-xt71w4nr	109	22	irregular	irregular	JJ
cord-018142-xt71w4nr	109	23	relapses	relapse	NNS
cord-018142-xt71w4nr	109	24	[	[	-LRB-
cord-018142-xt71w4nr	109	25	29	29	CD
cord-018142-xt71w4nr	109	26	]	]	-RRB-
cord-018142-xt71w4nr	109	27	.	.	.
cord-018142-xt71w4nr	110	1	HUS	HUS	NNP
cord-018142-xt71w4nr	110	2	comprises	comprise	VBZ
cord-018142-xt71w4nr	110	3	a	a	DT
cord-018142-xt71w4nr	110	4	combination	combination	NN
cord-018142-xt71w4nr	110	5	of	of	IN
cord-018142-xt71w4nr	110	6	mechanical	mechanical	JJ
cord-018142-xt71w4nr	110	7	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	110	8	anemia	anemia	NN
cord-018142-xt71w4nr	110	9	,	,	,
cord-018142-xt71w4nr	110	10	peripheral	peripheral	JJ
cord-018142-xt71w4nr	110	11	thrombocytopenia	thrombocytopenia	NN
cord-018142-xt71w4nr	110	12	and	and	CC
cord-018142-xt71w4nr	110	13	acute	acute	JJ
cord-018142-xt71w4nr	110	14	renal	renal	JJ
cord-018142-xt71w4nr	110	15	failure	failure	NN
cord-018142-xt71w4nr	110	16	.	.	.
cord-018142-xt71w4nr	111	1	The	the	DT
cord-018142-xt71w4nr	111	2	renal	renal	JJ
cord-018142-xt71w4nr	111	3	lesion	lesion	NN
cord-018142-xt71w4nr	111	4	is	be	VBZ
cord-018142-xt71w4nr	111	5	predominant	predominant	JJ
cord-018142-xt71w4nr	111	6	in	in	IN
cord-018142-xt71w4nr	111	7	all	all	DT
cord-018142-xt71w4nr	111	8	forms	form	NNS
cord-018142-xt71w4nr	111	9	and	and	CC
cord-018142-xt71w4nr	111	10	is	be	VBZ
cord-018142-xt71w4nr	111	11	classically	classically	RB
cord-018142-xt71w4nr	111	12	associated	associate	VBN
cord-018142-xt71w4nr	111	13	with	with	IN
cord-018142-xt71w4nr	111	14	severe	severe	JJ
cord-018142-xt71w4nr	111	15	hypertension	hypertension	NN
cord-018142-xt71w4nr	111	16	at	at	IN
cord-018142-xt71w4nr	111	17	the	the	DT
cord-018142-xt71w4nr	111	18	time	time	NN
cord-018142-xt71w4nr	111	19	of	of	IN
cord-018142-xt71w4nr	111	20	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	111	21	.	.	.
cord-018142-xt71w4nr	112	1	This	this	DT
cord-018142-xt71w4nr	112	2	hypertension	hypertension	NN
cord-018142-xt71w4nr	112	3	is	be	VBZ
cord-018142-xt71w4nr	112	4	more	more	RBR
cord-018142-xt71w4nr	112	5	severe	severe	JJ
cord-018142-xt71w4nr	112	6	and	and	CC
cord-018142-xt71w4nr	112	7	more	more	RBR
cord-018142-xt71w4nr	112	8	frequent	frequent	JJ
cord-018142-xt71w4nr	112	9	than	than	IN
cord-018142-xt71w4nr	112	10	during	during	IN
cord-018142-xt71w4nr	112	11	TTP	TTP	NNP
cord-018142-xt71w4nr	112	12	,	,	,
cord-018142-xt71w4nr	112	13	while	while	IN
cord-018142-xt71w4nr	112	14	neurological	neurological	JJ
cord-018142-xt71w4nr	112	15	signs	sign	NNS
cord-018142-xt71w4nr	112	16	are	be	VBP
cord-018142-xt71w4nr	112	17	less	less	RBR
cord-018142-xt71w4nr	112	18	frequent	frequent	JJ
cord-018142-xt71w4nr	112	19	than	than	IN
cord-018142-xt71w4nr	112	20	during	during	IN
cord-018142-xt71w4nr	112	21	TTP	TTP	NNP
cord-018142-xt71w4nr	112	22	.	.	.
cord-018142-xt71w4nr	113	1	Anemia	anemia	NN
cord-018142-xt71w4nr	113	2	and	and	CC
cord-018142-xt71w4nr	113	3	thrombocytopenia	thrombocytopenia	NN
cord-018142-xt71w4nr	113	4	have	have	VBP
cord-018142-xt71w4nr	113	5	similar	similar	JJ
cord-018142-xt71w4nr	113	6	characteristics	characteristic	NNS
cord-018142-xt71w4nr	113	7	to	to	IN
cord-018142-xt71w4nr	113	8	those	those	DT
cord-018142-xt71w4nr	113	9	of	of	IN
cord-018142-xt71w4nr	113	10	TTP	TTP	NNP
cord-018142-xt71w4nr	113	11	(	(	-LRB-
cord-018142-xt71w4nr	113	12	see	see	VB
cord-018142-xt71w4nr	113	13	above	above	RB
cord-018142-xt71w4nr	113	14	)	)	-RRB-
cord-018142-xt71w4nr	113	15	.	.	.
cord-018142-xt71w4nr	114	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-018142-xt71w4nr	114	2	can	can	MD
cord-018142-xt71w4nr	114	3	be	be	VB
cord-018142-xt71w4nr	114	4	more	more	RBR
cord-018142-xt71w4nr	114	5	severe	severe	JJ
cord-018142-xt71w4nr	114	6	than	than	IN
cord-018142-xt71w4nr	114	7	during	during	IN
cord-018142-xt71w4nr	114	8	TTP	TTP	NNP
cord-018142-xt71w4nr	114	9	.	.	.
cord-018142-xt71w4nr	115	1	Clotting	clotting	NN
cord-018142-xt71w4nr	115	2	abnormalities	abnormality	NNS
cord-018142-xt71w4nr	115	3	may	may	MD
cord-018142-xt71w4nr	115	4	be	be	VB
cord-018142-xt71w4nr	115	5	observed	observe	VBN
cord-018142-xt71w4nr	115	6	:	:	:
cord-018142-xt71w4nr	115	7	slight	slight	JJ
cord-018142-xt71w4nr	115	8	reduction	reduction	NN
cord-018142-xt71w4nr	115	9	of	of	IN
cord-018142-xt71w4nr	115	10	fibrinogen	fibrinogen	NN
cord-018142-xt71w4nr	115	11	and	and	CC
cord-018142-xt71w4nr	115	12	clotting	clotting	NN
cord-018142-xt71w4nr	115	13	factors	factor	NNS
cord-018142-xt71w4nr	115	14	V	v	NN
cord-018142-xt71w4nr	115	15	and	and	CC
cord-018142-xt71w4nr	115	16	VII	vii	NN
cord-018142-xt71w4nr	115	17	.	.	.
cord-018142-xt71w4nr	116	1	Elevation	elevation	NN
cord-018142-xt71w4nr	116	2	of	of	IN
cord-018142-xt71w4nr	116	3	fibrin	fibrin	NN
cord-018142-xt71w4nr	116	4	degradation	degradation	NN
cord-018142-xt71w4nr	116	5	products	product	NNS
cord-018142-xt71w4nr	116	6	,	,	,
cord-018142-xt71w4nr	116	7	tissue	tissue	NN
cord-018142-xt71w4nr	116	8	plasminogen	plasminogen	NN
cord-018142-xt71w4nr	116	9	activator	activator	NN
cord-018142-xt71w4nr	116	10	and	and	CC
cord-018142-xt71w4nr	116	11	PAI	PAI	NNP
cord-018142-xt71w4nr	116	12	reflect	reflect	VBP
cord-018142-xt71w4nr	116	13	activation	activation	NN
cord-018142-xt71w4nr	116	14	of	of	IN
cord-018142-xt71w4nr	116	15	homeostasis	homeostasis	NN
cord-018142-xt71w4nr	116	16	by	by	IN
cord-018142-xt71w4nr	116	17	tissue	tissue	NN
cord-018142-xt71w4nr	116	18	factor	factor	NN
cord-018142-xt71w4nr	116	19	in	in	IN
cord-018142-xt71w4nr	116	20	the	the	DT
cord-018142-xt71w4nr	116	21	kidney	kidney	NN
cord-018142-xt71w4nr	116	22	.	.	.
cord-018142-xt71w4nr	117	1	Kidney	kidney	NN
cord-018142-xt71w4nr	117	2	needle	needle	NN
cord-018142-xt71w4nr	117	3	biopsy	biopsy	NN
cord-018142-xt71w4nr	117	4	is	be	VBZ
cord-018142-xt71w4nr	117	5	only	only	RB
cord-018142-xt71w4nr	117	6	performed	perform	VBN
cord-018142-xt71w4nr	117	7	when	when	WRB
cord-018142-xt71w4nr	117	8	there	there	EX
cord-018142-xt71w4nr	117	9	is	be	VBZ
cord-018142-xt71w4nr	117	10	a	a	DT
cord-018142-xt71w4nr	117	11	doubt	doubt	NN
cord-018142-xt71w4nr	117	12	about	about	IN
cord-018142-xt71w4nr	117	13	the	the	DT
cord-018142-xt71w4nr	117	14	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	117	15	or	or	CC
cord-018142-xt71w4nr	117	16	in	in	IN
cord-018142-xt71w4nr	117	17	the	the	DT
cord-018142-xt71w4nr	117	18	case	case	NN
cord-018142-xt71w4nr	117	19	of	of	IN
cord-018142-xt71w4nr	117	20	persistent	persistent	JJ
cord-018142-xt71w4nr	117	21	renal	renal	JJ
cord-018142-xt71w4nr	117	22	failure	failure	NN
cord-018142-xt71w4nr	117	23	[	[	-LRB-
cord-018142-xt71w4nr	117	24	30	30	CD
cord-018142-xt71w4nr	117	25	]	]	-RRB-
cord-018142-xt71w4nr	117	26	.	.	.
cord-018142-xt71w4nr	118	1	Epidemic	epidemic	NN
cord-018142-xt71w4nr	118	2	(	(	-LRB-
cord-018142-xt71w4nr	118	3	post	post	JJ
cord-018142-xt71w4nr	118	4	-	-	JJ
cord-018142-xt71w4nr	118	5	diarrheal	diarrheal	JJ
cord-018142-xt71w4nr	118	6	)	)	-RRB-
cord-018142-xt71w4nr	118	7	HUS	HUS	NNP
cord-018142-xt71w4nr	118	8	.	.	.
cord-018142-xt71w4nr	119	1	Post	post	JJ
cord-018142-xt71w4nr	119	2	-	-	JJ
cord-018142-xt71w4nr	119	3	diarrheal	diarrheal	JJ
cord-018142-xt71w4nr	119	4	HUS	HUS	NNP
cord-018142-xt71w4nr	119	5	has	have	VBZ
cord-018142-xt71w4nr	119	6	a	a	DT
cord-018142-xt71w4nr	119	7	sudden	sudden	JJ
cord-018142-xt71w4nr	119	8	onset	onset	NN
cord-018142-xt71w4nr	119	9	in	in	IN
cord-018142-xt71w4nr	119	10	90	90	CD
cord-018142-xt71w4nr	119	11	%	%	NN
cord-018142-xt71w4nr	119	12	of	of	IN
cord-018142-xt71w4nr	119	13	cases	case	NNS
cord-018142-xt71w4nr	119	14	,	,	,
cord-018142-xt71w4nr	119	15	presenting	present	VBG
cord-018142-xt71w4nr	119	16	with	with	IN
cord-018142-xt71w4nr	119	17	diarrhea	diarrhea	NN
cord-018142-xt71w4nr	119	18	(	(	-LRB-
cord-018142-xt71w4nr	119	19	bloody	bloody	JJ
cord-018142-xt71w4nr	119	20	in	in	IN
cord-018142-xt71w4nr	119	21	70	70	CD
cord-018142-xt71w4nr	119	22	%	%	NN
cord-018142-xt71w4nr	119	23	of	of	IN
cord-018142-xt71w4nr	119	24	cases	case	NNS
cord-018142-xt71w4nr	119	25	and	and	CC
cord-018142-xt71w4nr	119	26	febrile	febrile	JJ
cord-018142-xt71w4nr	119	27	in	in	IN
cord-018142-xt71w4nr	119	28	50	50	CD
cord-018142-xt71w4nr	119	29	%	%	NN
cord-018142-xt71w4nr	119	30	of	of	IN
cord-018142-xt71w4nr	119	31	cases	case	NNS
cord-018142-xt71w4nr	119	32	)	)	-RRB-
cord-018142-xt71w4nr	119	33	.	.	.
cord-018142-xt71w4nr	120	1	It	-PRON-	PRP
cord-018142-xt71w4nr	120	2	is	be	VBZ
cord-018142-xt71w4nr	120	3	essentially	essentially	RB
cord-018142-xt71w4nr	120	4	observed	observe	VBN
cord-018142-xt71w4nr	120	5	in	in	IN
cord-018142-xt71w4nr	120	6	children	child	NNS
cord-018142-xt71w4nr	120	7	,	,	,
cord-018142-xt71w4nr	120	8	but	but	CC
cord-018142-xt71w4nr	120	9	also	also	RB
cord-018142-xt71w4nr	120	10	in	in	IN
cord-018142-xt71w4nr	120	11	adults	adult	NNS
cord-018142-xt71w4nr	120	12	.	.	.
cord-018142-xt71w4nr	121	1	The	the	DT
cord-018142-xt71w4nr	121	2	renal	renal	JJ
cord-018142-xt71w4nr	121	3	lesion	lesion	NN
cord-018142-xt71w4nr	121	4	appears	appear	VBZ
cord-018142-xt71w4nr	121	5	one	one	CD
cord-018142-xt71w4nr	121	6	week	week	NN
cord-018142-xt71w4nr	121	7	after	after	IN
cord-018142-xt71w4nr	121	8	onset	onset	NN
cord-018142-xt71w4nr	121	9	of	of	IN
cord-018142-xt71w4nr	121	10	the	the	DT
cord-018142-xt71w4nr	121	11	diarrhea	diarrhea	NN
cord-018142-xt71w4nr	121	12	(	(	-LRB-
cord-018142-xt71w4nr	121	13	which	which	WDT
cord-018142-xt71w4nr	121	14	has	have	VBZ
cord-018142-xt71w4nr	121	15	resolved	resolve	VBN
cord-018142-xt71w4nr	121	16	at	at	IN
cord-018142-xt71w4nr	121	17	the	the	DT
cord-018142-xt71w4nr	121	18	time	time	NN
cord-018142-xt71w4nr	121	19	of	of	IN
cord-018142-xt71w4nr	121	20	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	121	21	in	in	IN
cord-018142-xt71w4nr	121	22	50	50	CD
cord-018142-xt71w4nr	121	23	%	%	NN
cord-018142-xt71w4nr	121	24	of	of	IN
cord-018142-xt71w4nr	121	25	cases	case	NNS
cord-018142-xt71w4nr	121	26	)	)	-RRB-
cord-018142-xt71w4nr	121	27	.	.	.
cord-018142-xt71w4nr	122	1	Clinical	clinical	JJ
cord-018142-xt71w4nr	122	2	manifestations	manifestation	NNS
cord-018142-xt71w4nr	122	3	are	be	VBP
cord-018142-xt71w4nr	122	4	dominated	dominate	VBN
cord-018142-xt71w4nr	122	5	by	by	IN
cord-018142-xt71w4nr	122	6	renal	renal	JJ
cord-018142-xt71w4nr	122	7	failure	failure	NN
cord-018142-xt71w4nr	122	8	with	with	IN
cord-018142-xt71w4nr	122	9	severe	severe	JJ
cord-018142-xt71w4nr	122	10	proteinuria	proteinuria	NN
cord-018142-xt71w4nr	122	11	and	and	CC
cord-018142-xt71w4nr	122	12	hematuria	hematuria	NN
cord-018142-xt71w4nr	122	13	(	(	-LRB-
cord-018142-xt71w4nr	122	14	microscopic	microscopic	JJ
cord-018142-xt71w4nr	122	15	or	or	CC
cord-018142-xt71w4nr	122	16	macroscopic	macroscopic	JJ
cord-018142-xt71w4nr	122	17	)	)	-RRB-
cord-018142-xt71w4nr	122	18	.	.	.
cord-018142-xt71w4nr	123	1	Fifty	fifty	CD
cord-018142-xt71w4nr	123	2	percent	percent	NN
cord-018142-xt71w4nr	123	3	of	of	IN
cord-018142-xt71w4nr	123	4	children	child	NNS
cord-018142-xt71w4nr	123	5	are	be	VBP
cord-018142-xt71w4nr	123	6	anuric	anuric	RB
cord-018142-xt71w4nr	123	7	at	at	IN
cord-018142-xt71w4nr	123	8	the	the	DT
cord-018142-xt71w4nr	123	9	time	time	NN
cord-018142-xt71w4nr	123	10	of	of	IN
cord-018142-xt71w4nr	123	11	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	123	12	.	.	.
cord-018142-xt71w4nr	124	1	One	one	CD
cord-018142-xt71w4nr	124	2	half	half	NN
cord-018142-xt71w4nr	124	3	of	of	IN
cord-018142-xt71w4nr	124	4	patients	patient	NNS
cord-018142-xt71w4nr	124	5	with	with	IN
cord-018142-xt71w4nr	124	6	renal	renal	JJ
cord-018142-xt71w4nr	124	7	failure	failure	NN
cord-018142-xt71w4nr	124	8	will	will	MD
cord-018142-xt71w4nr	124	9	require	require	VB
cord-018142-xt71w4nr	124	10	dialysis	dialysis	NN
cord-018142-xt71w4nr	124	11	.	.	.
cord-018142-xt71w4nr	125	1	Severe	severe	JJ
cord-018142-xt71w4nr	125	2	hypertension	hypertension	NN
cord-018142-xt71w4nr	125	3	is	be	VBZ
cord-018142-xt71w4nr	125	4	often	often	RB
cord-018142-xt71w4nr	125	5	associated	associate	VBN
cord-018142-xt71w4nr	125	6	with	with	IN
cord-018142-xt71w4nr	125	7	marked	marked	JJ
cord-018142-xt71w4nr	125	8	hyponatremia	hyponatremia	NN
cord-018142-xt71w4nr	125	9	.	.	.
cord-018142-xt71w4nr	126	1	Central	central	JJ
cord-018142-xt71w4nr	126	2	nervous	nervous	JJ
cord-018142-xt71w4nr	126	3	system	system	NN
cord-018142-xt71w4nr	126	4	signs	sign	NNS
cord-018142-xt71w4nr	126	5	are	be	VBP
cord-018142-xt71w4nr	126	6	present	present	JJ
cord-018142-xt71w4nr	126	7	in	in	IN
cord-018142-xt71w4nr	126	8	10	10	CD
cord-018142-xt71w4nr	126	9	to	to	TO
cord-018142-xt71w4nr	126	10	30	30	CD
cord-018142-xt71w4nr	126	11	%	%	NN
cord-018142-xt71w4nr	126	12	of	of	IN
cord-018142-xt71w4nr	126	13	cases	case	NNS
cord-018142-xt71w4nr	126	14	,	,	,
cord-018142-xt71w4nr	126	15	often	often	RB
cord-018142-xt71w4nr	126	16	accentuated	accentuate	VBN
cord-018142-xt71w4nr	126	17	by	by	IN
cord-018142-xt71w4nr	126	18	hyponatremia	hyponatremia	NN
cord-018142-xt71w4nr	126	19	,	,	,
cord-018142-xt71w4nr	126	20	consisting	consist	VBG
cord-018142-xt71w4nr	126	21	of	of	IN
cord-018142-xt71w4nr	126	22	irritability	irritability	NN
cord-018142-xt71w4nr	126	23	,	,	,
cord-018142-xt71w4nr	126	24	drowsiness	drowsiness	NN
cord-018142-xt71w4nr	126	25	,	,	,
cord-018142-xt71w4nr	126	26	convulsions	convulsion	NNS
cord-018142-xt71w4nr	126	27	or	or	CC
cord-018142-xt71w4nr	126	28	even	even	RB
cord-018142-xt71w4nr	126	29	coma	coma	NN
cord-018142-xt71w4nr	126	30	.	.	.
cord-018142-xt71w4nr	127	1	The	the	DT
cord-018142-xt71w4nr	127	2	microorganism	microorganism	NN
cord-018142-xt71w4nr	127	3	responsible	responsible	JJ
cord-018142-xt71w4nr	127	4	is	be	VBZ
cord-018142-xt71w4nr	127	5	often	often	RB
cord-018142-xt71w4nr	127	6	no	no	RB
cord-018142-xt71w4nr	127	7	longer	long	RBR
cord-018142-xt71w4nr	127	8	present	present	JJ
cord-018142-xt71w4nr	127	9	in	in	IN
cord-018142-xt71w4nr	127	10	the	the	DT
cord-018142-xt71w4nr	127	11	stools	stool	NNS
cord-018142-xt71w4nr	127	12	at	at	IN
cord-018142-xt71w4nr	127	13	the	the	DT
cord-018142-xt71w4nr	127	14	time	time	NN
cord-018142-xt71w4nr	127	15	of	of	IN
cord-018142-xt71w4nr	127	16	the	the	DT
cord-018142-xt71w4nr	127	17	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	127	18	of	of	IN
cord-018142-xt71w4nr	127	19	HUS	HUS	NNP
cord-018142-xt71w4nr	127	20	,	,	,
cord-018142-xt71w4nr	127	21	but	but	CC
cord-018142-xt71w4nr	127	22	the	the	DT
cord-018142-xt71w4nr	127	23	toxin	toxin	NN
cord-018142-xt71w4nr	127	24	can	can	MD
cord-018142-xt71w4nr	127	25	be	be	VB
cord-018142-xt71w4nr	127	26	isolated	isolate	VBN
cord-018142-xt71w4nr	127	27	in	in	IN
cord-018142-xt71w4nr	127	28	two	two	CD
cord-018142-xt71w4nr	127	29	thirds	third	NNS
cord-018142-xt71w4nr	127	30	of	of	IN
cord-018142-xt71w4nr	127	31	cases	case	NNS
cord-018142-xt71w4nr	127	32	.	.	.
cord-018142-xt71w4nr	128	1	The	the	DT
cord-018142-xt71w4nr	128	2	clinical	clinical	JJ
cord-018142-xt71w4nr	128	3	and	and	CC
cord-018142-xt71w4nr	128	4	laboratory	laboratory	NN
cord-018142-xt71w4nr	128	5	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	128	6	of	of	IN
cord-018142-xt71w4nr	128	7	HUS	HUS	NNP
cord-018142-xt71w4nr	128	8	is	be	VBZ
cord-018142-xt71w4nr	128	9	usually	usually	RB
cord-018142-xt71w4nr	128	10	easy	easy	JJ
cord-018142-xt71w4nr	128	11	to	to	TO
cord-018142-xt71w4nr	128	12	establish	establish	VB
cord-018142-xt71w4nr	128	13	and	and	CC
cord-018142-xt71w4nr	128	14	kidney	kidney	NN
cord-018142-xt71w4nr	128	15	needle	needle	NN
cord-018142-xt71w4nr	128	16	biopsy	biopsy	NN
cord-018142-xt71w4nr	128	17	is	be	VBZ
cord-018142-xt71w4nr	128	18	rarely	rarely	RB
cord-018142-xt71w4nr	128	19	necessary	necessary	JJ
cord-018142-xt71w4nr	128	20	.	.	.
cord-018142-xt71w4nr	129	1	Atypical	atypical	JJ
cord-018142-xt71w4nr	129	2	HUS	hus	NN
cord-018142-xt71w4nr	129	3	.	.	.
cord-018142-xt71w4nr	130	1	The	the	DT
cord-018142-xt71w4nr	130	2	clinical	clinical	JJ
cord-018142-xt71w4nr	130	3	features	feature	NNS
cord-018142-xt71w4nr	130	4	are	be	VBP
cord-018142-xt71w4nr	130	5	often	often	RB
cord-018142-xt71w4nr	130	6	less	less	RBR
cord-018142-xt71w4nr	130	7	typical	typical	JJ
cord-018142-xt71w4nr	130	8	,	,	,
cord-018142-xt71w4nr	130	9	and	and	CC
cord-018142-xt71w4nr	130	10	kidney	kidney	NN
cord-018142-xt71w4nr	130	11	needle	needle	NN
cord-018142-xt71w4nr	130	12	biopsy	biopsy	NN
cord-018142-xt71w4nr	130	13	is	be	VBZ
cord-018142-xt71w4nr	130	14	more	more	RBR
cord-018142-xt71w4nr	130	15	often	often	RB
cord-018142-xt71w4nr	130	16	required	require	VBN
cord-018142-xt71w4nr	130	17	to	to	TO
cord-018142-xt71w4nr	130	18	establish	establish	VB
cord-018142-xt71w4nr	130	19	the	the	DT
cord-018142-xt71w4nr	130	20	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	130	21	.	.	.
cord-018142-xt71w4nr	131	1	Acute	acute	JJ
cord-018142-xt71w4nr	131	2	renal	renal	JJ
cord-018142-xt71w4nr	131	3	failure	failure	NN
cord-018142-xt71w4nr	131	4	is	be	VBZ
cord-018142-xt71w4nr	131	5	often	often	RB
cord-018142-xt71w4nr	131	6	anuric	anuric	JJ
cord-018142-xt71w4nr	131	7	with	with	IN
cord-018142-xt71w4nr	131	8	moderate	moderate	JJ
cord-018142-xt71w4nr	131	9	proteinuria	proteinuria	NN
cord-018142-xt71w4nr	131	10	(	(	-LRB-
cord-018142-xt71w4nr	131	11	1	1	CD
cord-018142-xt71w4nr	131	12	to	to	IN
cord-018142-xt71w4nr	131	13	2	2	CD
cord-018142-xt71w4nr	131	14	g/24	g/24	NN
cord-018142-xt71w4nr	131	15	h	h	NN
cord-018142-xt71w4nr	131	16	)	)	-RRB-
cord-018142-xt71w4nr	131	17	,	,	,
cord-018142-xt71w4nr	131	18	but	but	CC
cord-018142-xt71w4nr	131	19	proteinuria	proteinuria	NN
cord-018142-xt71w4nr	131	20	may	may	MD
cord-018142-xt71w4nr	131	21	also	also	RB
cord-018142-xt71w4nr	131	22	exceed	exceed	VB
cord-018142-xt71w4nr	131	23	3	3	CD
cord-018142-xt71w4nr	131	24	g/24h	g/24h	NNP
cord-018142-xt71w4nr	131	25	.	.	.
cord-018142-xt71w4nr	132	1	Microscopic	microscopic	JJ
cord-018142-xt71w4nr	132	2	hematuria	hematuria	NN
cord-018142-xt71w4nr	132	3	is	be	VBZ
cord-018142-xt71w4nr	132	4	frequent	frequent	JJ
cord-018142-xt71w4nr	132	5	and	and	CC
cord-018142-xt71w4nr	132	6	hypertension	hypertension	NN
cord-018142-xt71w4nr	132	7	is	be	VBZ
cord-018142-xt71w4nr	132	8	present	present	JJ
cord-018142-xt71w4nr	132	9	in	in	IN
cord-018142-xt71w4nr	132	10	50	50	CD
cord-018142-xt71w4nr	132	11	%	%	NN
cord-018142-xt71w4nr	132	12	of	of	IN
cord-018142-xt71w4nr	132	13	cases	case	NNS
cord-018142-xt71w4nr	132	14	at	at	IN
cord-018142-xt71w4nr	132	15	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	132	16	.	.	.
cord-018142-xt71w4nr	133	1	Thrombocytopenia	Thrombocytopenia	NNP
cord-018142-xt71w4nr	133	2	is	be	VBZ
cord-018142-xt71w4nr	133	3	present	present	JJ
cord-018142-xt71w4nr	133	4	in	in	IN
cord-018142-xt71w4nr	133	5	only	only	RB
cord-018142-xt71w4nr	133	6	50	50	CD
cord-018142-xt71w4nr	133	7	%	%	NN
cord-018142-xt71w4nr	133	8	of	of	IN
cord-018142-xt71w4nr	133	9	cases	case	NNS
cord-018142-xt71w4nr	133	10	at	at	IN
cord-018142-xt71w4nr	133	11	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	133	12	.	.	.
cord-018142-xt71w4nr	134	1	There	there	EX
cord-018142-xt71w4nr	134	2	are	be	VBP
cord-018142-xt71w4nr	134	3	few	few	JJ
cord-018142-xt71w4nr	134	4	or	or	CC
cord-018142-xt71w4nr	134	5	no	no	DT
cord-018142-xt71w4nr	134	6	extra	extra	JJ
cord-018142-xt71w4nr	134	7	-	-	JJ
cord-018142-xt71w4nr	134	8	renal	renal	JJ
cord-018142-xt71w4nr	134	9	signs	sign	NNS
cord-018142-xt71w4nr	134	10	(	(	-LRB-
cord-018142-xt71w4nr	134	11	fever	fever	NN
cord-018142-xt71w4nr	134	12	,	,	,
cord-018142-xt71w4nr	134	13	neurological	neurological	JJ
cord-018142-xt71w4nr	134	14	signs	sign	NNS
cord-018142-xt71w4nr	134	15	)	)	-RRB-
cord-018142-xt71w4nr	134	16	.	.	.
cord-018142-xt71w4nr	135	1	A	a	DT
cord-018142-xt71w4nr	135	2	history	history	NN
cord-018142-xt71w4nr	135	3	of	of	IN
cord-018142-xt71w4nr	135	4	infection	infection	NN
cord-018142-xt71w4nr	135	5	is	be	VBZ
cord-018142-xt71w4nr	135	6	frequently	frequently	RB
cord-018142-xt71w4nr	135	7	reported	report	VBN
cord-018142-xt71w4nr	135	8	.	.	.
cord-018142-xt71w4nr	136	1	Adults	adult	NNS
cord-018142-xt71w4nr	136	2	sometimes	sometimes	RB
cord-018142-xt71w4nr	136	3	present	present	VBP
cord-018142-xt71w4nr	136	4	a	a	DT
cord-018142-xt71w4nr	136	5	context	context	NN
cord-018142-xt71w4nr	136	6	of	of	IN
cord-018142-xt71w4nr	136	7	auto	auto	NN
cord-018142-xt71w4nr	136	8	-	-	HYPH
cord-018142-xt71w4nr	136	9	immune	immune	JJ
cord-018142-xt71w4nr	136	10	disease	disease	NN
cord-018142-xt71w4nr	136	11	,	,	,
cord-018142-xt71w4nr	136	12	drugs	drug	NNS
cord-018142-xt71w4nr	136	13	or	or	CC
cord-018142-xt71w4nr	136	14	pregnancy	pregnancy	NN
cord-018142-xt71w4nr	136	15	.	.	.
cord-018142-xt71w4nr	137	1	The	the	DT
cord-018142-xt71w4nr	137	2	assessment	assessment	NN
cord-018142-xt71w4nr	137	3	of	of	IN
cord-018142-xt71w4nr	137	4	atypical	atypical	JJ
cord-018142-xt71w4nr	137	5	HUS	HUS	NNP
cord-018142-xt71w4nr	137	6	must	must	MD
cord-018142-xt71w4nr	137	7	include	include	VB
cord-018142-xt71w4nr	137	8	assays	assay	NNS
cord-018142-xt71w4nr	137	9	of	of	IN
cord-018142-xt71w4nr	137	10	complement	complement	JJ
cord-018142-xt71w4nr	137	11	fractions	fraction	NNS
cord-018142-xt71w4nr	137	12	(	(	-LRB-
cord-018142-xt71w4nr	137	13	C3	C3	NNP
cord-018142-xt71w4nr	137	14	,	,	,
cord-018142-xt71w4nr	137	15	C4	C4	NNP
cord-018142-xt71w4nr	137	16	,	,	,
cord-018142-xt71w4nr	137	17	CH50	CH50	NNP
cord-018142-xt71w4nr	137	18	)	)	-RRB-
cord-018142-xt71w4nr	137	19	,	,	,
cord-018142-xt71w4nr	137	20	and	and	CC
cord-018142-xt71w4nr	137	21	the	the	DT
cord-018142-xt71w4nr	137	22	activity	activity	NN
cord-018142-xt71w4nr	137	23	of	of	IN
cord-018142-xt71w4nr	137	24	the	the	DT
cord-018142-xt71w4nr	137	25	ADAMTS-13	ADAMTS-13	NNP
cord-018142-xt71w4nr	137	26	protein	protein	NN
cord-018142-xt71w4nr	137	27	and	and	CC
cord-018142-xt71w4nr	137	28	the	the	DT
cord-018142-xt71w4nr	137	29	inhibitory	inhibitory	JJ
cord-018142-xt71w4nr	137	30	protein	protein	NN
cord-018142-xt71w4nr	137	31	of	of	IN
cord-018142-xt71w4nr	137	32	the	the	DT
cord-018142-xt71w4nr	137	33	alternative	alternative	JJ
cord-018142-xt71w4nr	137	34	complement	complement	NN
cord-018142-xt71w4nr	137	35	pathway	pathway	NN
cord-018142-xt71w4nr	137	36	(	(	-LRB-
cord-018142-xt71w4nr	137	37	and	and	CC
cord-018142-xt71w4nr	137	38	a	a	DT
cord-018142-xt71w4nr	137	39	test	test	NN
cord-018142-xt71w4nr	137	40	for	for	IN
cord-018142-xt71w4nr	137	41	a	a	DT
cord-018142-xt71w4nr	137	42	mutation	mutation	NN
cord-018142-xt71w4nr	137	43	of	of	IN
cord-018142-xt71w4nr	137	44	the	the	DT
cord-018142-xt71w4nr	137	45	corresponding	correspond	VBG
cord-018142-xt71w4nr	137	46	gene	gene	NN
cord-018142-xt71w4nr	137	47	)	)	-RRB-
cord-018142-xt71w4nr	137	48	.	.	.
cord-018142-xt71w4nr	138	1	The	the	DT
cord-018142-xt71w4nr	138	2	clinical	clinical	JJ
cord-018142-xt71w4nr	138	3	features	feature	NNS
cord-018142-xt71w4nr	138	4	of	of	IN
cord-018142-xt71w4nr	138	5	HUS	HUS	NNP
cord-018142-xt71w4nr	138	6	and	and	CC
cord-018142-xt71w4nr	138	7	TTP	TTP	NNP
cord-018142-xt71w4nr	138	8	tend	tend	VBP
cord-018142-xt71w4nr	138	9	to	to	TO
cord-018142-xt71w4nr	138	10	overlap	overlap	VB
cord-018142-xt71w4nr	138	11	and	and	CC
cord-018142-xt71w4nr	138	12	it	-PRON-	PRP
cord-018142-xt71w4nr	138	13	can	can	MD
cord-018142-xt71w4nr	138	14	be	be	VB
cord-018142-xt71w4nr	138	15	difficult	difficult	JJ
cord-018142-xt71w4nr	138	16	,	,	,
cord-018142-xt71w4nr	138	17	on	on	IN
cord-018142-xt71w4nr	138	18	admission	admission	NN
cord-018142-xt71w4nr	138	19	,	,	,
cord-018142-xt71w4nr	138	20	to	to	TO
cord-018142-xt71w4nr	138	21	distinguish	distinguish	VB
cord-018142-xt71w4nr	138	22	between	between	IN
cord-018142-xt71w4nr	138	23	these	these	DT
cord-018142-xt71w4nr	138	24	two	two	CD
cord-018142-xt71w4nr	138	25	diagnoses	diagnosis	NNS
cord-018142-xt71w4nr	138	26	.	.	.
cord-018142-xt71w4nr	139	1	The	the	DT
cord-018142-xt71w4nr	139	2	neurological	neurological	JJ
cord-018142-xt71w4nr	139	3	signs	sign	NNS
cord-018142-xt71w4nr	139	4	are	be	VBP
cord-018142-xt71w4nr	139	5	variable	variable	JJ
cord-018142-xt71w4nr	139	6	,	,	,
cord-018142-xt71w4nr	139	7	ranging	range	VBG
cord-018142-xt71w4nr	139	8	from	from	IN
cord-018142-xt71w4nr	139	9	simple	simple	JJ
cord-018142-xt71w4nr	139	10	confusion	confusion	NN
cord-018142-xt71w4nr	139	11	to	to	IN
cord-018142-xt71w4nr	139	12	coma	coma	NN
cord-018142-xt71w4nr	139	13	with	with	IN
cord-018142-xt71w4nr	139	14	generalized	generalized	JJ
cord-018142-xt71w4nr	139	15	convulsions	convulsion	NNS
cord-018142-xt71w4nr	139	16	and	and	CC
cord-018142-xt71w4nr	139	17	focal	focal	JJ
cord-018142-xt71w4nr	139	18	deficits	deficit	NNS
cord-018142-xt71w4nr	139	19	,	,	,
cord-018142-xt71w4nr	139	20	aphasia	aphasia	NN
cord-018142-xt71w4nr	139	21	,	,	,
cord-018142-xt71w4nr	139	22	diplopia	diplopia	NN
cord-018142-xt71w4nr	139	23	,	,	,
cord-018142-xt71w4nr	139	24	facial	facial	JJ
cord-018142-xt71w4nr	139	25	paralysis	paralysis	NN
cord-018142-xt71w4nr	139	26	,	,	,
cord-018142-xt71w4nr	139	27	etc	etc	FW
cord-018142-xt71w4nr	139	28	.	.	.
cord-018142-xt71w4nr	140	1	Renal	renal	JJ
cord-018142-xt71w4nr	140	2	involvement	involvement	NN
cord-018142-xt71w4nr	140	3	is	be	VBZ
cord-018142-xt71w4nr	140	4	also	also	RB
cord-018142-xt71w4nr	140	5	heterogeneous	heterogeneous	JJ
cord-018142-xt71w4nr	140	6	,	,	,
cord-018142-xt71w4nr	140	7	ranging	range	VBG
cord-018142-xt71w4nr	140	8	from	from	IN
cord-018142-xt71w4nr	140	9	normal	normal	JJ
cord-018142-xt71w4nr	140	10	renal	renal	JJ
cord-018142-xt71w4nr	140	11	function	function	NN
cord-018142-xt71w4nr	140	12	to	to	TO
cord-018142-xt71w4nr	140	13	anuric	anuric	VB
cord-018142-xt71w4nr	140	14	acute	acute	JJ
cord-018142-xt71w4nr	140	15	renal	renal	JJ
cord-018142-xt71w4nr	140	16	failure	failure	NN
cord-018142-xt71w4nr	140	17	.	.	.
cord-018142-xt71w4nr	141	1	Laboratory	laboratory	NN
cord-018142-xt71w4nr	141	2	test	test	NN
cord-018142-xt71w4nr	141	3	results	result	NNS
cord-018142-xt71w4nr	141	4	can	can	MD
cord-018142-xt71w4nr	141	5	confirm	confirm	VB
cord-018142-xt71w4nr	141	6	the	the	DT
cord-018142-xt71w4nr	141	7	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	141	8	,	,	,
cord-018142-xt71w4nr	141	9	but	but	CC
cord-018142-xt71w4nr	141	10	often	often	RB
cord-018142-xt71w4nr	141	11	only	only	RB
cord-018142-xt71w4nr	141	12	retrospectively	retrospectively	RB
cord-018142-xt71w4nr	141	13	.	.	.
cord-018142-xt71w4nr	142	1	The	the	DT
cord-018142-xt71w4nr	142	2	prognosis	prognosis	NN
cord-018142-xt71w4nr	142	3	of	of	IN
cord-018142-xt71w4nr	142	4	TMA	TMA	NNP
cord-018142-xt71w4nr	142	5	prior	prior	RB
cord-018142-xt71w4nr	142	6	to	to	IN
cord-018142-xt71w4nr	142	7	plasma	plasma	NN
cord-018142-xt71w4nr	142	8	therapy	therapy	NN
cord-018142-xt71w4nr	142	9	in	in	IN
cord-018142-xt71w4nr	142	10	the	the	DT
cord-018142-xt71w4nr	142	11	ICU	ICU	NNP
cord-018142-xt71w4nr	142	12	was	be	VBD
cord-018142-xt71w4nr	142	13	extremely	extremely	RB
cord-018142-xt71w4nr	142	14	poor	poor	JJ
cord-018142-xt71w4nr	142	15	.	.	.
cord-018142-xt71w4nr	143	1	Plasma	plasma	NN
cord-018142-xt71w4nr	143	2	therapy	therapy	NN
cord-018142-xt71w4nr	143	3	has	have	VBZ
cord-018142-xt71w4nr	143	4	considerably	considerably	RB
cord-018142-xt71w4nr	143	5	improved	improve	VBN
cord-018142-xt71w4nr	143	6	the	the	DT
cord-018142-xt71w4nr	143	7	prognosis	prognosis	NN
cord-018142-xt71w4nr	143	8	of	of	IN
cord-018142-xt71w4nr	143	9	these	these	DT
cord-018142-xt71w4nr	143	10	usually	usually	RB
cord-018142-xt71w4nr	143	11	fatal	fatal	JJ
cord-018142-xt71w4nr	143	12	diseases	disease	NNS
cord-018142-xt71w4nr	143	13	(	(	-LRB-
cord-018142-xt71w4nr	143	14	3-month	3-month	CD
cord-018142-xt71w4nr	143	15	mortality	mortality	NN
cord-018142-xt71w4nr	143	16	greater	great	JJR
cord-018142-xt71w4nr	143	17	than	than	IN
cord-018142-xt71w4nr	143	18	90	90	CD
cord-018142-xt71w4nr	143	19	%	%	NN
cord-018142-xt71w4nr	143	20	for	for	IN
cord-018142-xt71w4nr	143	21	acute	acute	JJ
cord-018142-xt71w4nr	143	22	forms	form	NNS
cord-018142-xt71w4nr	143	23	of	of	IN
cord-018142-xt71w4nr	143	24	TTP	ttp	NN
cord-018142-xt71w4nr	143	25	without	without	IN
cord-018142-xt71w4nr	143	26	treatment	treatment	NN
cord-018142-xt71w4nr	143	27	)	)	-RRB-
cord-018142-xt71w4nr	143	28	[	[	-LRB-
cord-018142-xt71w4nr	143	29	27	27	CD
cord-018142-xt71w4nr	143	30	]	]	-RRB-
cord-018142-xt71w4nr	143	31	.	.	.
cord-018142-xt71w4nr	144	1	In	in	IN
cord-018142-xt71w4nr	144	2	a	a	DT
cord-018142-xt71w4nr	144	3	recent	recent	JJ
cord-018142-xt71w4nr	144	4	retrospective	retrospective	JJ
cord-018142-xt71w4nr	144	5	study	study	NN
cord-018142-xt71w4nr	144	6	of	of	IN
cord-018142-xt71w4nr	144	7	64	64	CD
cord-018142-xt71w4nr	144	8	patients	patient	NNS
cord-018142-xt71w4nr	144	9	admitted	admit	VBN
cord-018142-xt71w4nr	144	10	to	to	IN
cord-018142-xt71w4nr	144	11	the	the	DT
cord-018142-xt71w4nr	144	12	adult	adult	NN
cord-018142-xt71w4nr	144	13	ICU	ICU	NNP
cord-018142-xt71w4nr	144	14	for	for	IN
cord-018142-xt71w4nr	144	15	TMA	TMA	NNP
cord-018142-xt71w4nr	144	16	,	,	,
cord-018142-xt71w4nr	144	17	the	the	DT
cord-018142-xt71w4nr	144	18	mortality	mortality	NN
cord-018142-xt71w4nr	144	19	rate	rate	NN
cord-018142-xt71w4nr	144	20	was	be	VBD
cord-018142-xt71w4nr	144	21	35	35	CD
cord-018142-xt71w4nr	144	22	%	%	NN
cord-018142-xt71w4nr	144	23	[	[	-LRB-
cord-018142-xt71w4nr	144	24	11	11	CD
cord-018142-xt71w4nr	144	25	]	]	-RRB-
cord-018142-xt71w4nr	144	26	and	and	CC
cord-018142-xt71w4nr	144	27	Coppo	Coppo	NNP
cord-018142-xt71w4nr	144	28	et	et	NNP
cord-018142-xt71w4nr	144	29	al	al	NNP
cord-018142-xt71w4nr	144	30	.	.	.
cord-018142-xt71w4nr	145	1	reported	report	VBD
cord-018142-xt71w4nr	145	2	a	a	DT
cord-018142-xt71w4nr	145	3	mortality	mortality	NN
cord-018142-xt71w4nr	145	4	rate	rate	NN
cord-018142-xt71w4nr	145	5	of	of	IN
cord-018142-xt71w4nr	145	6	25	25	CD
cord-018142-xt71w4nr	145	7	%	%	NN
cord-018142-xt71w4nr	145	8	in	in	IN
cord-018142-xt71w4nr	145	9	intensive	intensive	JJ
cord-018142-xt71w4nr	145	10	care	care	NN
cord-018142-xt71w4nr	145	11	patients	patient	NNS
cord-018142-xt71w4nr	145	12	with	with	IN
cord-018142-xt71w4nr	145	13	TMA	TMA	NNP
cord-018142-xt71w4nr	145	14	[	[	-LRB-
cord-018142-xt71w4nr	145	15	1	1	CD
cord-018142-xt71w4nr	145	16	]	]	-RRB-
cord-018142-xt71w4nr	145	17	.	.	.
cord-018142-xt71w4nr	146	1	The	the	DT
cord-018142-xt71w4nr	146	2	mortality	mortality	NN
cord-018142-xt71w4nr	146	3	related	relate	VBN
cord-018142-xt71w4nr	146	4	to	to	IN
cord-018142-xt71w4nr	146	5	TMA	TMA	NNP
cord-018142-xt71w4nr	146	6	in	in	IN
cord-018142-xt71w4nr	146	7	intensive	intensive	JJ
cord-018142-xt71w4nr	146	8	care	care	NN
cord-018142-xt71w4nr	146	9	is	be	VBZ
cord-018142-xt71w4nr	146	10	partly	partly	RB
cord-018142-xt71w4nr	146	11	dependent	dependent	JJ
cord-018142-xt71w4nr	146	12	on	on	IN
cord-018142-xt71w4nr	146	13	the	the	DT
cord-018142-xt71w4nr	146	14	treatment	treatment	NN
cord-018142-xt71w4nr	146	15	used	use	VBN
cord-018142-xt71w4nr	146	16	.	.	.
cord-018142-xt71w4nr	147	1	In	in	IN
cord-018142-xt71w4nr	147	2	recent	recent	JJ
cord-018142-xt71w4nr	147	3	studies	study	NNS
cord-018142-xt71w4nr	147	4	[	[	-LRB-
cord-018142-xt71w4nr	147	5	31±33	31±33	NNP
cord-018142-xt71w4nr	147	6	]	]	-RRB-
cord-018142-xt71w4nr	147	7	,	,	,
cord-018142-xt71w4nr	147	8	the	the	DT
cord-018142-xt71w4nr	147	9	survival	survival	NN
cord-018142-xt71w4nr	147	10	rate	rate	NN
cord-018142-xt71w4nr	147	11	of	of	IN
cord-018142-xt71w4nr	147	12	patients	patient	NNS
cord-018142-xt71w4nr	147	13	treated	treat	VBN
cord-018142-xt71w4nr	147	14	with	with	IN
cord-018142-xt71w4nr	147	15	plasma	plasma	NN
cord-018142-xt71w4nr	147	16	exchange	exchange	NN
cord-018142-xt71w4nr	147	17	is	be	VBZ
cord-018142-xt71w4nr	147	18	78	78	CD
cord-018142-xt71w4nr	147	19	to	to	TO
cord-018142-xt71w4nr	147	20	90	90	CD
cord-018142-xt71w4nr	147	21	%	%	NN
cord-018142-xt71w4nr	147	22	.	.	.
cord-018142-xt71w4nr	148	1	In	in	IN
cord-018142-xt71w4nr	148	2	the	the	DT
cord-018142-xt71w4nr	148	3	study	study	NN
cord-018142-xt71w4nr	148	4	by	by	IN
cord-018142-xt71w4nr	148	5	Pene	Pene	NNP
cord-018142-xt71w4nr	148	6	et	et	NNP
cord-018142-xt71w4nr	148	7	al	al	NNP
cord-018142-xt71w4nr	148	8	.	.	.
cord-018142-xt71w4nr	149	1	[	[	-LRB-
cord-018142-xt71w4nr	149	2	11	11	CD
cord-018142-xt71w4nr	149	3	]	]	-RRB-
cord-018142-xt71w4nr	149	4	,	,	,
cord-018142-xt71w4nr	149	5	the	the	DT
cord-018142-xt71w4nr	149	6	mortality	mortality	NN
cord-018142-xt71w4nr	149	7	at	at	IN
cord-018142-xt71w4nr	149	8	90	90	CD
cord-018142-xt71w4nr	149	9	days	day	NNS
cord-018142-xt71w4nr	149	10	was	be	VBD
cord-018142-xt71w4nr	149	11	22	22	CD
cord-018142-xt71w4nr	149	12	%	%	NN
cord-018142-xt71w4nr	149	13	when	when	WRB
cord-018142-xt71w4nr	149	14	plasma	plasma	NN
cord-018142-xt71w4nr	149	15	exchange	exchange	NN
cord-018142-xt71w4nr	149	16	was	be	VBD
cord-018142-xt71w4nr	149	17	performed	perform	VBN
cord-018142-xt71w4nr	149	18	and	and	CC
cord-018142-xt71w4nr	149	19	59	59	CD
cord-018142-xt71w4nr	149	20	%	%	NN
cord-018142-xt71w4nr	149	21	in	in	IN
cord-018142-xt71w4nr	149	22	the	the	DT
cord-018142-xt71w4nr	149	23	absence	absence	NN
cord-018142-xt71w4nr	149	24	of	of	IN
cord-018142-xt71w4nr	149	25	plasma	plasma	NN
cord-018142-xt71w4nr	149	26	exchange	exchange	NN
cord-018142-xt71w4nr	149	27	.	.	.
cord-018142-xt71w4nr	150	1	The	the	DT
cord-018142-xt71w4nr	150	2	study	study	NN
cord-018142-xt71w4nr	150	3	by	by	IN
cord-018142-xt71w4nr	150	4	Rock	Rock	NNP
cord-018142-xt71w4nr	150	5	et	et	NNP
cord-018142-xt71w4nr	150	6	al	al	NNP
cord-018142-xt71w4nr	150	7	.	.	.
cord-018142-xt71w4nr	151	1	[	[	-LRB-
cord-018142-xt71w4nr	151	2	33	33	CD
cord-018142-xt71w4nr	151	3	]	]	-RRB-
cord-018142-xt71w4nr	151	4	confirmed	confirm	VBD
cord-018142-xt71w4nr	151	5	the	the	DT
cord-018142-xt71w4nr	151	6	superiority	superiority	NN
cord-018142-xt71w4nr	151	7	of	of	IN
cord-018142-xt71w4nr	151	8	plasma	plasma	NN
cord-018142-xt71w4nr	151	9	exchange	exchange	NN
cord-018142-xt71w4nr	151	10	compared	compare	VBN
cord-018142-xt71w4nr	151	11	to	to	IN
cord-018142-xt71w4nr	151	12	fresh	fresh	JJ
cord-018142-xt71w4nr	151	13	frozen	frozen	JJ
cord-018142-xt71w4nr	151	14	plasma	plasma	NN
cord-018142-xt71w4nr	151	15	(	(	-LRB-
cord-018142-xt71w4nr	151	16	FFP	ffp	NN
cord-018142-xt71w4nr	151	17	)	)	-RRB-
cord-018142-xt71w4nr	151	18	infusion	infusion	NN
cord-018142-xt71w4nr	151	19	in	in	IN
cord-018142-xt71w4nr	151	20	terms	term	NNS
cord-018142-xt71w4nr	151	21	of	of	IN
cord-018142-xt71w4nr	151	22	survival	survival	NN
cord-018142-xt71w4nr	151	23	and	and	CC
cord-018142-xt71w4nr	151	24	response	response	NN
cord-018142-xt71w4nr	151	25	to	to	IN
cord-018142-xt71w4nr	151	26	treatment	treatment	NN
cord-018142-xt71w4nr	151	27	(	(	-LRB-
cord-018142-xt71w4nr	151	28	78	78	CD
cord-018142-xt71w4nr	151	29	versus	versus	IN
cord-018142-xt71w4nr	151	30	49	49	CD
cord-018142-xt71w4nr	151	31	%	%	NN
cord-018142-xt71w4nr	151	32	)	)	-RRB-
cord-018142-xt71w4nr	151	33	.	.	.
cord-018142-xt71w4nr	152	1	The	the	DT
cord-018142-xt71w4nr	152	2	use	use	NN
cord-018142-xt71w4nr	152	3	of	of	IN
cord-018142-xt71w4nr	152	4	plasma	plasma	NN
cord-018142-xt71w4nr	152	5	exchange	exchange	NN
cord-018142-xt71w4nr	152	6	is	be	VBZ
cord-018142-xt71w4nr	152	7	positively	positively	RB
cord-018142-xt71w4nr	152	8	correlated	correlate	VBN
cord-018142-xt71w4nr	152	9	with	with	IN
cord-018142-xt71w4nr	152	10	survival	survival	NN
cord-018142-xt71w4nr	152	11	.	.	.
cord-018142-xt71w4nr	153	1	Overall	overall	RB
cord-018142-xt71w4nr	153	2	,	,	,
cord-018142-xt71w4nr	153	3	TMA	TMA	NNP
cord-018142-xt71w4nr	153	4	syndromes	syndrome	NNS
cord-018142-xt71w4nr	153	5	with	with	IN
cord-018142-xt71w4nr	153	6	severe	severe	JJ
cord-018142-xt71w4nr	153	7	organ	organ	NN
cord-018142-xt71w4nr	153	8	dysfunction	dysfunction	NN
cord-018142-xt71w4nr	153	9	requiring	require	VBG
cord-018142-xt71w4nr	153	10	admission	admission	NN
cord-018142-xt71w4nr	153	11	to	to	IN
cord-018142-xt71w4nr	153	12	the	the	DT
cord-018142-xt71w4nr	153	13	ICU	ICU	NNP
cord-018142-xt71w4nr	153	14	are	be	VBP
cord-018142-xt71w4nr	153	15	associated	associate	VBN
cord-018142-xt71w4nr	153	16	with	with	IN
cord-018142-xt71w4nr	153	17	a	a	DT
cord-018142-xt71w4nr	153	18	high	high	JJ
cord-018142-xt71w4nr	153	19	mortality	mortality	NN
cord-018142-xt71w4nr	153	20	.	.	.
cord-018142-xt71w4nr	154	1	The	the	DT
cord-018142-xt71w4nr	154	2	main	main	JJ
cord-018142-xt71w4nr	154	3	cause	cause	NN
cord-018142-xt71w4nr	154	4	of	of	IN
cord-018142-xt71w4nr	154	5	death	death	NN
cord-018142-xt71w4nr	154	6	in	in	IN
cord-018142-xt71w4nr	154	7	these	these	DT
cord-018142-xt71w4nr	154	8	patients	patient	NNS
cord-018142-xt71w4nr	154	9	in	in	IN
cord-018142-xt71w4nr	154	10	the	the	DT
cord-018142-xt71w4nr	154	11	ICU	ICU	NNP
cord-018142-xt71w4nr	154	12	is	be	VBZ
cord-018142-xt71w4nr	154	13	multiple	multiple	JJ
cord-018142-xt71w4nr	154	14	organ	organ	NN
cord-018142-xt71w4nr	154	15	failure	failure	NN
cord-018142-xt71w4nr	154	16	(	(	-LRB-
cord-018142-xt71w4nr	154	17	MOF	MOF	NNP
cord-018142-xt71w4nr	154	18	)	)	-RRB-
cord-018142-xt71w4nr	154	19	.	.	.
cord-018142-xt71w4nr	155	1	An	an	DT
cord-018142-xt71w4nr	155	2	infection	infection	NN
cord-018142-xt71w4nr	155	3	associated	associate	VBN
cord-018142-xt71w4nr	155	4	with	with	IN
cord-018142-xt71w4nr	155	5	TMA	TMA	NNP
cord-018142-xt71w4nr	155	6	syndrome	syndrome	NN
cord-018142-xt71w4nr	155	7	has	have	VBZ
cord-018142-xt71w4nr	155	8	a	a	DT
cord-018142-xt71w4nr	155	9	major	major	JJ
cord-018142-xt71w4nr	155	10	impact	impact	NN
cord-018142-xt71w4nr	155	11	on	on	IN
cord-018142-xt71w4nr	155	12	the	the	DT
cord-018142-xt71w4nr	155	13	outcome	outcome	NN
cord-018142-xt71w4nr	155	14	of	of	IN
cord-018142-xt71w4nr	155	15	these	these	DT
cord-018142-xt71w4nr	155	16	patients	patient	NNS
cord-018142-xt71w4nr	155	17	.	.	.
cord-018142-xt71w4nr	156	1	The	the	DT
cord-018142-xt71w4nr	156	2	presence	presence	NN
cord-018142-xt71w4nr	156	3	of	of	IN
cord-018142-xt71w4nr	156	4	a	a	DT
cord-018142-xt71w4nr	156	5	neurological	neurological	JJ
cord-018142-xt71w4nr	156	6	deficit	deficit	NN
cord-018142-xt71w4nr	156	7	,	,	,
cord-018142-xt71w4nr	156	8	possibly	possibly	RB
cord-018142-xt71w4nr	156	9	evaluated	evaluate	VBN
cord-018142-xt71w4nr	156	10	by	by	IN
cord-018142-xt71w4nr	156	11	the	the	DT
cord-018142-xt71w4nr	156	12	Glasgow	Glasgow	NNP
cord-018142-xt71w4nr	156	13	Coma	Coma	NNP
cord-018142-xt71w4nr	156	14	Scale	Scale	NNP
cord-018142-xt71w4nr	156	15	,	,	,
cord-018142-xt71w4nr	156	16	is	be	VBZ
cord-018142-xt71w4nr	156	17	the	the	DT
cord-018142-xt71w4nr	156	18	main	main	JJ
cord-018142-xt71w4nr	156	19	negative	negative	JJ
cord-018142-xt71w4nr	156	20	prognostic	prognostic	JJ
cord-018142-xt71w4nr	156	21	factor	factor	NN
cord-018142-xt71w4nr	156	22	correlated	correlate	VBN
cord-018142-xt71w4nr	156	23	with	with	IN
cord-018142-xt71w4nr	156	24	mortality	mortality	NN
cord-018142-xt71w4nr	156	25	[	[	-LRB-
cord-018142-xt71w4nr	156	26	11	11	CD
cord-018142-xt71w4nr	156	27	,	,	,
cord-018142-xt71w4nr	156	28	32	32	CD
cord-018142-xt71w4nr	156	29	,	,	,
cord-018142-xt71w4nr	156	30	34	34	CD
cord-018142-xt71w4nr	156	31	,	,	,
cord-018142-xt71w4nr	156	32	35	35	CD
cord-018142-xt71w4nr	156	33	]	]	-RRB-
cord-018142-xt71w4nr	156	34	.	.	.
cord-018142-xt71w4nr	157	1	Other	other	JJ
cord-018142-xt71w4nr	157	2	prognostic	prognostic	JJ
cord-018142-xt71w4nr	157	3	factors	factor	NNS
cord-018142-xt71w4nr	157	4	have	have	VBP
cord-018142-xt71w4nr	157	5	also	also	RB
cord-018142-xt71w4nr	157	6	been	be	VBN
cord-018142-xt71w4nr	157	7	demonstrated	demonstrate	VBN
cord-018142-xt71w4nr	157	8	:	:	:
cord-018142-xt71w4nr	157	9	the	the	DT
cord-018142-xt71w4nr	157	10	SAPS	SAPS	NNP
cord-018142-xt71w4nr	157	11	II	II	NNP
cord-018142-xt71w4nr	157	12	score	score	NN
cord-018142-xt71w4nr	157	13	,	,	,
cord-018142-xt71w4nr	157	14	need	need	VBP
cord-018142-xt71w4nr	157	15	for	for	IN
cord-018142-xt71w4nr	157	16	vasoactive	vasoactive	JJ
cord-018142-xt71w4nr	157	17	support	support	NN
cord-018142-xt71w4nr	157	18	,	,	,
cord-018142-xt71w4nr	157	19	bilirubin	bilirubin	JJ
cord-018142-xt71w4nr	157	20	level	level	NN
cord-018142-xt71w4nr	157	21	,	,	,
cord-018142-xt71w4nr	157	22	LDH	LDH	NNP
cord-018142-xt71w4nr	157	23	kinetics	kinetic	NNS
cord-018142-xt71w4nr	157	24	on	on	IN
cord-018142-xt71w4nr	157	25	the	the	DT
cord-018142-xt71w4nr	157	26	3rd	3rd	JJ
cord-018142-xt71w4nr	157	27	day	day	NN
cord-018142-xt71w4nr	157	28	of	of	IN
cord-018142-xt71w4nr	157	29	treatment	treatment	NN
cord-018142-xt71w4nr	157	30	[	[	-LRB-
cord-018142-xt71w4nr	157	31	11	11	CD
cord-018142-xt71w4nr	157	32	]	]	-RRB-
cord-018142-xt71w4nr	157	33	.	.	.
cord-018142-xt71w4nr	158	1	Predictive	predictive	JJ
cord-018142-xt71w4nr	158	2	scores	score	NNS
cord-018142-xt71w4nr	158	3	for	for	IN
cord-018142-xt71w4nr	158	4	TTP	TTP	NNP
cord-018142-xt71w4nr	158	5	have	have	VBP
cord-018142-xt71w4nr	158	6	been	be	VBN
cord-018142-xt71w4nr	158	7	established	establish	VBN
cord-018142-xt71w4nr	158	8	,	,	,
cord-018142-xt71w4nr	158	9	but	but	CC
cord-018142-xt71w4nr	158	10	their	-PRON-	PRP$
cord-018142-xt71w4nr	158	11	value	value	NN
cord-018142-xt71w4nr	158	12	has	have	VBZ
cord-018142-xt71w4nr	158	13	not	not	RB
cord-018142-xt71w4nr	158	14	yet	yet	RB
cord-018142-xt71w4nr	158	15	been	be	VBN
cord-018142-xt71w4nr	158	16	validated	validate	VBN
cord-018142-xt71w4nr	158	17	[	[	-LRB-
cord-018142-xt71w4nr	158	18	35	35	CD
cord-018142-xt71w4nr	158	19	]	]	-RRB-
cord-018142-xt71w4nr	158	20	.	.	.
cord-018142-xt71w4nr	159	1	Unlike	unlike	IN
cord-018142-xt71w4nr	159	2	other	other	JJ
cord-018142-xt71w4nr	159	3	diseases	disease	NNS
cord-018142-xt71w4nr	159	4	usually	usually	RB
cord-018142-xt71w4nr	159	5	observed	observe	VBN
cord-018142-xt71w4nr	159	6	in	in	IN
cord-018142-xt71w4nr	159	7	intensive	intensive	JJ
cord-018142-xt71w4nr	159	8	care	care	NN
cord-018142-xt71w4nr	159	9	,	,	,
cord-018142-xt71w4nr	159	10	the	the	DT
cord-018142-xt71w4nr	159	11	development	development	NN
cord-018142-xt71w4nr	159	12	of	of	IN
cord-018142-xt71w4nr	159	13	acute	acute	JJ
cord-018142-xt71w4nr	159	14	renal	renal	JJ
cord-018142-xt71w4nr	159	15	failure	failure	NN
cord-018142-xt71w4nr	159	16	or	or	CC
cord-018142-xt71w4nr	159	17	the	the	DT
cord-018142-xt71w4nr	159	18	need	need	NN
cord-018142-xt71w4nr	159	19	for	for	IN
cord-018142-xt71w4nr	159	20	dialysis	dialysis	NN
cord-018142-xt71w4nr	159	21	in	in	IN
cord-018142-xt71w4nr	159	22	a	a	DT
cord-018142-xt71w4nr	159	23	context	context	NN
cord-018142-xt71w4nr	159	24	of	of	IN
cord-018142-xt71w4nr	159	25	TMA	TMA	NNP
cord-018142-xt71w4nr	159	26	are	be	VBP
cord-018142-xt71w4nr	159	27	not	not	RB
cord-018142-xt71w4nr	159	28	correlated	correlate	VBN
cord-018142-xt71w4nr	159	29	with	with	IN
cord-018142-xt71w4nr	159	30	mortality	mortality	NN
cord-018142-xt71w4nr	159	31	[	[	-LRB-
cord-018142-xt71w4nr	159	32	11	11	CD
cord-018142-xt71w4nr	159	33	,	,	,
cord-018142-xt71w4nr	159	34	33	33	CD
cord-018142-xt71w4nr	159	35	,	,	,
cord-018142-xt71w4nr	159	36	36	36	CD
cord-018142-xt71w4nr	159	37	]	]	-RRB-
cord-018142-xt71w4nr	159	38	.	.	.
cord-018142-xt71w4nr	160	1	According	accord	VBG
cord-018142-xt71w4nr	160	2	to	to	IN
cord-018142-xt71w4nr	160	3	Lara	Lara	NNP
cord-018142-xt71w4nr	160	4	et	et	NNP
cord-018142-xt71w4nr	160	5	al	al	NNP
cord-018142-xt71w4nr	160	6	.	.	.
cord-018142-xt71w4nr	161	1	[	[	-LRB-
cord-018142-xt71w4nr	161	2	32	32	CD
cord-018142-xt71w4nr	161	3	]	]	-RRB-
cord-018142-xt71w4nr	161	4	,	,	,
cord-018142-xt71w4nr	161	5	renal	renal	JJ
cord-018142-xt71w4nr	161	6	failure	failure	NN
cord-018142-xt71w4nr	161	7	is	be	VBZ
cord-018142-xt71w4nr	161	8	correlated	correlate	VBN
cord-018142-xt71w4nr	161	9	with	with	IN
cord-018142-xt71w4nr	161	10	a	a	DT
cord-018142-xt71w4nr	161	11	risk	risk	NN
cord-018142-xt71w4nr	161	12	of	of	IN
cord-018142-xt71w4nr	161	13	relapse	relapse	NN
cord-018142-xt71w4nr	161	14	of	of	IN
cord-018142-xt71w4nr	161	15	TMA	TMA	NNP
cord-018142-xt71w4nr	161	16	,	,	,
cord-018142-xt71w4nr	161	17	which	which	WDT
cord-018142-xt71w4nr	161	18	has	have	VBZ
cord-018142-xt71w4nr	161	19	a	a	DT
cord-018142-xt71w4nr	161	20	poor	poor	JJ
cord-018142-xt71w4nr	161	21	prognosis	prognosis	NN
cord-018142-xt71w4nr	161	22	,	,	,
cord-018142-xt71w4nr	161	23	but	but	CC
cord-018142-xt71w4nr	161	24	the	the	DT
cord-018142-xt71w4nr	161	25	renal	renal	JJ
cord-018142-xt71w4nr	161	26	prognosis	prognosis	NN
cord-018142-xt71w4nr	161	27	of	of	IN
cord-018142-xt71w4nr	161	28	TTP	TTP	NNP
cord-018142-xt71w4nr	161	29	is	be	VBZ
cord-018142-xt71w4nr	161	30	generally	generally	RB
cord-018142-xt71w4nr	161	31	good	good	JJ
cord-018142-xt71w4nr	161	32	.	.	.
cord-018142-xt71w4nr	162	1	The	the	DT
cord-018142-xt71w4nr	162	2	survival	survival	NN
cord-018142-xt71w4nr	162	3	rates	rate	NNS
cord-018142-xt71w4nr	162	4	of	of	IN
cord-018142-xt71w4nr	162	5	post	post	JJ
cord-018142-xt71w4nr	162	6	-	-	JJ
cord-018142-xt71w4nr	162	7	diarrheal	diarrheal	JJ
cord-018142-xt71w4nr	162	8	HUS	HUS	NNP
cord-018142-xt71w4nr	162	9	are	be	VBP
cord-018142-xt71w4nr	162	10	excellent	excellent	JJ
cord-018142-xt71w4nr	162	11	in	in	IN
cord-018142-xt71w4nr	162	12	response	response	NN
cord-018142-xt71w4nr	162	13	to	to	IN
cord-018142-xt71w4nr	162	14	symptomatic	symptomatic	JJ
cord-018142-xt71w4nr	162	15	treatment	treatment	NN
cord-018142-xt71w4nr	162	16	alone	alone	RB
cord-018142-xt71w4nr	162	17	,	,	,
cord-018142-xt71w4nr	162	18	and	and	CC
cord-018142-xt71w4nr	162	19	admission	admission	NN
cord-018142-xt71w4nr	162	20	to	to	IN
cord-018142-xt71w4nr	162	21	the	the	DT
cord-018142-xt71w4nr	162	22	ICU	ICU	NNP
cord-018142-xt71w4nr	162	23	is	be	VBZ
cord-018142-xt71w4nr	162	24	only	only	RB
cord-018142-xt71w4nr	162	25	rarely	rarely	RB
cord-018142-xt71w4nr	162	26	necessary	necessary	JJ
cord-018142-xt71w4nr	162	27	.	.	.
cord-018142-xt71w4nr	163	1	The	the	DT
cord-018142-xt71w4nr	163	2	mortality	mortality	NN
cord-018142-xt71w4nr	163	3	of	of	IN
cord-018142-xt71w4nr	163	4	post	post	JJ
cord-018142-xt71w4nr	163	5	-	-	JJ
cord-018142-xt71w4nr	163	6	diarrheal	diarrheal	JJ
cord-018142-xt71w4nr	163	7	HUS	HUS	NNP
cord-018142-xt71w4nr	163	8	varies	vary	VBZ
cord-018142-xt71w4nr	163	9	between	between	IN
cord-018142-xt71w4nr	163	10	3	3	CD
cord-018142-xt71w4nr	163	11	and	and	CC
cord-018142-xt71w4nr	163	12	8	8	CD
cord-018142-xt71w4nr	163	13	%	%	NN
cord-018142-xt71w4nr	163	14	and	and	CC
cord-018142-xt71w4nr	163	15	is	be	VBZ
cord-018142-xt71w4nr	163	16	related	relate	VBN
cord-018142-xt71w4nr	163	17	to	to	IN
cord-018142-xt71w4nr	163	18	gastrointestinal	gastrointestinal	JJ
cord-018142-xt71w4nr	163	19	and	and	CC
cord-018142-xt71w4nr	163	20	neurological	neurological	JJ
cord-018142-xt71w4nr	163	21	lesions	lesion	NNS
cord-018142-xt71w4nr	163	22	.	.	.
cord-018142-xt71w4nr	164	1	The	the	DT
cord-018142-xt71w4nr	164	2	short	short	JJ
cord-018142-xt71w4nr	164	3	-	-	HYPH
cord-018142-xt71w4nr	164	4	term	term	NN
cord-018142-xt71w4nr	164	5	renal	renal	JJ
cord-018142-xt71w4nr	164	6	prognosis	prognosis	NN
cord-018142-xt71w4nr	164	7	is	be	VBZ
cord-018142-xt71w4nr	164	8	good	good	JJ
cord-018142-xt71w4nr	164	9	(	(	-LRB-
cord-018142-xt71w4nr	164	10	improvement	improvement	NN
cord-018142-xt71w4nr	164	11	of	of	IN
cord-018142-xt71w4nr	164	12	renal	renal	JJ
cord-018142-xt71w4nr	164	13	function	function	NN
cord-018142-xt71w4nr	164	14	over	over	IN
cord-018142-xt71w4nr	164	15	several	several	JJ
cord-018142-xt71w4nr	164	16	days	day	NNS
cord-018142-xt71w4nr	164	17	to	to	IN
cord-018142-xt71w4nr	164	18	several	several	JJ
cord-018142-xt71w4nr	164	19	weeks	week	NNS
cord-018142-xt71w4nr	164	20	)	)	-RRB-
cord-018142-xt71w4nr	164	21	.	.	.
cord-018142-xt71w4nr	165	1	However	however	RB
cord-018142-xt71w4nr	165	2	,	,	,
cord-018142-xt71w4nr	165	3	one	one	CD
cord-018142-xt71w4nr	165	4	quarter	quarter	NN
cord-018142-xt71w4nr	165	5	to	to	IN
cord-018142-xt71w4nr	165	6	one	one	CD
cord-018142-xt71w4nr	165	7	third	third	NN
cord-018142-xt71w4nr	165	8	of	of	IN
cord-018142-xt71w4nr	165	9	children	child	NNS
cord-018142-xt71w4nr	165	10	still	still	RB
cord-018142-xt71w4nr	165	11	present	present	VBP
cord-018142-xt71w4nr	165	12	renal	renal	JJ
cord-018142-xt71w4nr	165	13	sequelae	sequela	NNS
cord-018142-xt71w4nr	165	14	10	10	CD
cord-018142-xt71w4nr	165	15	years	year	NNS
cord-018142-xt71w4nr	165	16	later	later	RB
cord-018142-xt71w4nr	165	17	(	(	-LRB-
cord-018142-xt71w4nr	165	18	proteinuria	proteinuria	NN
cord-018142-xt71w4nr	165	19	and/or	and/or	CC
cord-018142-xt71w4nr	165	20	renal	renal	JJ
cord-018142-xt71w4nr	165	21	failure	failure	NN
cord-018142-xt71w4nr	165	22	)	)	-RRB-
cord-018142-xt71w4nr	165	23	with	with	IN
cord-018142-xt71w4nr	165	24	end	end	NN
cord-018142-xt71w4nr	165	25	-	-	HYPH
cord-018142-xt71w4nr	165	26	stage	stage	NN
cord-018142-xt71w4nr	165	27	chronic	chronic	JJ
cord-018142-xt71w4nr	165	28	renal	renal	JJ
cord-018142-xt71w4nr	165	29	failure	failure	NN
cord-018142-xt71w4nr	165	30	in	in	IN
cord-018142-xt71w4nr	165	31	3	3	CD
cord-018142-xt71w4nr	165	32	to	to	IN
cord-018142-xt71w4nr	165	33	4	4	CD
cord-018142-xt71w4nr	165	34	%	%	NN
cord-018142-xt71w4nr	165	35	of	of	IN
cord-018142-xt71w4nr	165	36	cases	case	NNS
cord-018142-xt71w4nr	165	37	.	.	.
cord-018142-xt71w4nr	166	1	Atypical	atypical	JJ
cord-018142-xt71w4nr	166	2	HUS	hus	NN
cord-018142-xt71w4nr	166	3	in	in	IN
cord-018142-xt71w4nr	166	4	children	child	NNS
cord-018142-xt71w4nr	166	5	has	have	VBZ
cord-018142-xt71w4nr	166	6	a	a	DT
cord-018142-xt71w4nr	166	7	poor	poor	JJ
cord-018142-xt71w4nr	166	8	prognosis	prognosis	NN
cord-018142-xt71w4nr	166	9	,	,	,
cord-018142-xt71w4nr	166	10	frequently	frequently	RB
cord-018142-xt71w4nr	166	11	resulting	result	VBG
cord-018142-xt71w4nr	166	12	in	in	IN
cord-018142-xt71w4nr	166	13	end	end	NN
cord-018142-xt71w4nr	166	14	-	-	HYPH
cord-018142-xt71w4nr	166	15	stage	stage	NN
cord-018142-xt71w4nr	166	16	chronic	chronic	JJ
cord-018142-xt71w4nr	166	17	renal	renal	JJ
cord-018142-xt71w4nr	166	18	failure	failure	NN
cord-018142-xt71w4nr	166	19	and	and	CC
cord-018142-xt71w4nr	166	20	a	a	DT
cord-018142-xt71w4nr	166	21	high	high	JJ
cord-018142-xt71w4nr	166	22	post	post	JJ
cord-018142-xt71w4nr	166	23	-	-	JJ
cord-018142-xt71w4nr	166	24	transplantation	transplantation	JJ
cord-018142-xt71w4nr	166	25	recurrence	recurrence	NN
cord-018142-xt71w4nr	166	26	rate	rate	NN
cord-018142-xt71w4nr	166	27	.	.	.
cord-018142-xt71w4nr	167	1	Atypical	atypical	JJ
cord-018142-xt71w4nr	167	2	HUS	hus	NN
cord-018142-xt71w4nr	167	3	in	in	IN
cord-018142-xt71w4nr	167	4	adults	adult	NNS
cord-018142-xt71w4nr	167	5	is	be	VBZ
cord-018142-xt71w4nr	167	6	a	a	DT
cord-018142-xt71w4nr	167	7	serious	serious	JJ
cord-018142-xt71w4nr	167	8	disease	disease	NN
cord-018142-xt71w4nr	167	9	in	in	IN
cord-018142-xt71w4nr	167	10	which	which	WDT
cord-018142-xt71w4nr	167	11	the	the	DT
cord-018142-xt71w4nr	167	12	prognosis	prognosis	NN
cord-018142-xt71w4nr	167	13	depends	depend	VBZ
cord-018142-xt71w4nr	167	14	on	on	IN
cord-018142-xt71w4nr	167	15	the	the	DT
cord-018142-xt71w4nr	167	16	etiology	etiology	NN
cord-018142-xt71w4nr	167	17	of	of	IN
cord-018142-xt71w4nr	167	18	HUS	HUS	NNP
cord-018142-xt71w4nr	167	19	.	.	.
cord-018142-xt71w4nr	168	1	The	the	DT
cord-018142-xt71w4nr	168	2	concomitant	concomitant	JJ
cord-018142-xt71w4nr	168	3	presence	presence	NN
cord-018142-xt71w4nr	168	4	of	of	IN
cord-018142-xt71w4nr	168	5	advanced	advanced	JJ
cord-018142-xt71w4nr	168	6	cancer	cancer	NN
cord-018142-xt71w4nr	168	7	,	,	,
cord-018142-xt71w4nr	168	8	HIV	HIV	NNP
cord-018142-xt71w4nr	168	9	infection	infection	NN
cord-018142-xt71w4nr	168	10	,	,	,
cord-018142-xt71w4nr	168	11	mitomycin	mitomycin	NNS
cord-018142-xt71w4nr	168	12	C	C	NNP
cord-018142-xt71w4nr	168	13	therapy	therapy	NN
cord-018142-xt71w4nr	168	14	and	and	CC
cord-018142-xt71w4nr	168	15	post	post	JJ
cord-018142-xt71w4nr	168	16	-	-	JJ
cord-018142-xt71w4nr	168	17	partum	partum	JJ
cord-018142-xt71w4nr	168	18	etiology	etiology	NN
cord-018142-xt71w4nr	168	19	carries	carry	VBZ
cord-018142-xt71w4nr	168	20	a	a	DT
cord-018142-xt71w4nr	168	21	very	very	RB
cord-018142-xt71w4nr	168	22	poor	poor	JJ
cord-018142-xt71w4nr	168	23	prognosis	prognosis	NN
cord-018142-xt71w4nr	168	24	.	.	.
cord-018142-xt71w4nr	169	1	The	the	DT
cord-018142-xt71w4nr	169	2	intensive	intensive	JJ
cord-018142-xt71w4nr	169	3	care	care	NN
cord-018142-xt71w4nr	169	4	mortality	mortality	NN
cord-018142-xt71w4nr	169	5	rate	rate	NN
cord-018142-xt71w4nr	169	6	of	of	IN
cord-018142-xt71w4nr	169	7	atypical	atypical	JJ
cord-018142-xt71w4nr	169	8	HUS	hus	NN
cord-018142-xt71w4nr	169	9	is	be	VBZ
cord-018142-xt71w4nr	169	10	10	10	CD
cord-018142-xt71w4nr	169	11	to	to	TO
cord-018142-xt71w4nr	169	12	20	20	CD
cord-018142-xt71w4nr	169	13	%	%	NN
cord-018142-xt71w4nr	169	14	.	.	.
cord-018142-xt71w4nr	170	1	Twenty	twenty	CD
cord-018142-xt71w4nr	170	2	-	-	HYPH
cord-018142-xt71w4nr	170	3	five	five	CD
cord-018142-xt71w4nr	170	4	to	to	TO
cord-018142-xt71w4nr	170	5	50	50	CD
cord-018142-xt71w4nr	170	6	%	%	NN
cord-018142-xt71w4nr	170	7	of	of	IN
cord-018142-xt71w4nr	170	8	these	these	DT
cord-018142-xt71w4nr	170	9	patients	patient	NNS
cord-018142-xt71w4nr	170	10	will	will	MD
cord-018142-xt71w4nr	170	11	require	require	VB
cord-018142-xt71w4nr	170	12	chronic	chronic	JJ
cord-018142-xt71w4nr	170	13	dialysis	dialysis	NN
cord-018142-xt71w4nr	170	14	.	.	.
cord-018142-xt71w4nr	171	1	Only	only	RB
cord-018142-xt71w4nr	171	2	50	50	CD
cord-018142-xt71w4nr	171	3	%	%	NN
cord-018142-xt71w4nr	171	4	of	of	IN
cord-018142-xt71w4nr	171	5	survivors	survivor	NNS
cord-018142-xt71w4nr	171	6	are	be	VBP
cord-018142-xt71w4nr	171	7	completely	completely	RB
cord-018142-xt71w4nr	171	8	cured	cure	VBN
cord-018142-xt71w4nr	171	9	without	without	IN
cord-018142-xt71w4nr	171	10	sequelae	sequela	NNS
cord-018142-xt71w4nr	171	11	.	.	.
cord-018142-xt71w4nr	172	1	In	in	IN
cord-018142-xt71w4nr	172	2	patients	patient	NNS
cord-018142-xt71w4nr	172	3	with	with	IN
cord-018142-xt71w4nr	172	4	underlying	underlying	JJ
cord-018142-xt71w4nr	172	5	nephropathy	nephropathy	NN
cord-018142-xt71w4nr	172	6	,	,	,
cord-018142-xt71w4nr	172	7	chronic	chronic	JJ
cord-018142-xt71w4nr	172	8	renal	renal	JJ
cord-018142-xt71w4nr	172	9	failure	failure	NN
cord-018142-xt71w4nr	172	10	persists	persist	VBZ
cord-018142-xt71w4nr	172	11	after	after	IN
cord-018142-xt71w4nr	172	12	the	the	DT
cord-018142-xt71w4nr	172	13	acute	acute	JJ
cord-018142-xt71w4nr	172	14	episode	episode	NN
cord-018142-xt71w4nr	172	15	in	in	IN
cord-018142-xt71w4nr	172	16	70	70	CD
cord-018142-xt71w4nr	172	17	%	%	NN
cord-018142-xt71w4nr	172	18	of	of	IN
cord-018142-xt71w4nr	172	19	cases	case	NNS
cord-018142-xt71w4nr	172	20	.	.	.
cord-018142-xt71w4nr	173	1	Long	long	JJ
cord-018142-xt71w4nr	173	2	-	-	HYPH
cord-018142-xt71w4nr	173	3	term	term	NN
cord-018142-xt71w4nr	173	4	recurrences	recurrence	NNS
cord-018142-xt71w4nr	173	5	are	be	VBP
cord-018142-xt71w4nr	173	6	possible	possible	JJ
cord-018142-xt71w4nr	173	7	,	,	,
cord-018142-xt71w4nr	173	8	especially	especially	RB
cord-018142-xt71w4nr	173	9	when	when	WRB
cord-018142-xt71w4nr	173	10	the	the	DT
cord-018142-xt71w4nr	173	11	cause	cause	NN
cord-018142-xt71w4nr	173	12	of	of	IN
cord-018142-xt71w4nr	173	13	HUS	HUS	NNP
cord-018142-xt71w4nr	173	14	persists	persist	VBZ
cord-018142-xt71w4nr	173	15	,	,	,
cord-018142-xt71w4nr	173	16	but	but	CC
cord-018142-xt71w4nr	173	17	are	be	VBP
cord-018142-xt71w4nr	173	18	less	less	RBR
cord-018142-xt71w4nr	173	19	frequent	frequent	JJ
cord-018142-xt71w4nr	173	20	than	than	IN
cord-018142-xt71w4nr	173	21	for	for	IN
cord-018142-xt71w4nr	173	22	TTP	TTP	NNP
cord-018142-xt71w4nr	173	23	.	.	.
cord-018142-xt71w4nr	174	1	z	z	NNP
cord-018142-xt71w4nr	174	2	Management	Management	NNP
cord-018142-xt71w4nr	174	3	TMA	TMA	NNP
cord-018142-xt71w4nr	174	4	always	always	RB
cord-018142-xt71w4nr	174	5	requires	require	VBZ
cord-018142-xt71w4nr	174	6	emergency	emergency	NN
cord-018142-xt71w4nr	174	7	treatment	treatment	NN
cord-018142-xt71w4nr	174	8	.	.	.
cord-018142-xt71w4nr	175	1	Admission	admission	NN
cord-018142-xt71w4nr	175	2	to	to	IN
cord-018142-xt71w4nr	175	3	intensive	intensive	JJ
cord-018142-xt71w4nr	175	4	care	care	NN
cord-018142-xt71w4nr	175	5	,	,	,
cord-018142-xt71w4nr	175	6	in	in	IN
cord-018142-xt71w4nr	175	7	addition	addition	NN
cord-018142-xt71w4nr	175	8	to	to	IN
cord-018142-xt71w4nr	175	9	the	the	DT
cord-018142-xt71w4nr	175	10	usual	usual	JJ
cord-018142-xt71w4nr	175	11	criteria	criterion	NNS
cord-018142-xt71w4nr	175	12	of	of	IN
cord-018142-xt71w4nr	175	13	organ	organ	NN
cord-018142-xt71w4nr	175	14	failure	failure	NN
cord-018142-xt71w4nr	175	15	,	,	,
cord-018142-xt71w4nr	175	16	must	must	MD
cord-018142-xt71w4nr	175	17	be	be	VB
cord-018142-xt71w4nr	175	18	proposed	propose	VBN
cord-018142-xt71w4nr	175	19	in	in	IN
cord-018142-xt71w4nr	175	20	all	all	DT
cord-018142-xt71w4nr	175	21	patients	patient	NNS
cord-018142-xt71w4nr	175	22	with	with	IN
cord-018142-xt71w4nr	175	23	severe	severe	JJ
cord-018142-xt71w4nr	175	24	thrombocytopenia	thrombocytopenia	NN
cord-018142-xt71w4nr	175	25	(	(	-LRB-
cord-018142-xt71w4nr	175	26	less	less	JJR
cord-018142-xt71w4nr	175	27	than	than	IN
cord-018142-xt71w4nr	175	28	50,000	50,000	CD
cord-018142-xt71w4nr	175	29	/	/	SYM
cord-018142-xt71w4nr	175	30	mm	mm	NN
cord-018142-xt71w4nr	175	31	3	3	CD
cord-018142-xt71w4nr	175	32	)	)	-RRB-
cord-018142-xt71w4nr	175	33	,	,	,
cord-018142-xt71w4nr	175	34	due	due	IN
cord-018142-xt71w4nr	175	35	to	to	IN
cord-018142-xt71w4nr	175	36	the	the	DT
cord-018142-xt71w4nr	175	37	high	high	JJ
cord-018142-xt71w4nr	175	38	frequency	frequency	NN
cord-018142-xt71w4nr	175	39	of	of	IN
cord-018142-xt71w4nr	175	40	organ	organ	NN
cord-018142-xt71w4nr	175	41	dysfunction	dysfunction	NN
cord-018142-xt71w4nr	175	42	at	at	IN
cord-018142-xt71w4nr	175	43	the	the	DT
cord-018142-xt71w4nr	175	44	acute	acute	JJ
cord-018142-xt71w4nr	175	45	phase	phase	NN
cord-018142-xt71w4nr	175	46	of	of	IN
cord-018142-xt71w4nr	175	47	the	the	DT
cord-018142-xt71w4nr	175	48	disease	disease	NN
cord-018142-xt71w4nr	175	49	.	.	.
cord-018142-xt71w4nr	176	1	Symptomatic	symptomatic	JJ
cord-018142-xt71w4nr	176	2	treatment	treatment	NN
cord-018142-xt71w4nr	176	3	is	be	VBZ
cord-018142-xt71w4nr	176	4	required	require	VBN
cord-018142-xt71w4nr	176	5	in	in	IN
cord-018142-xt71w4nr	176	6	all	all	DT
cord-018142-xt71w4nr	176	7	forms	form	NNS
cord-018142-xt71w4nr	176	8	of	of	IN
cord-018142-xt71w4nr	176	9	TMA	TMA	NNP
cord-018142-xt71w4nr	176	10	.	.	.
cord-018142-xt71w4nr	177	1	TMA	TMA	NNP
cord-018142-xt71w4nr	177	2	disorders	disorder	NNS
cord-018142-xt71w4nr	177	3	always	always	RB
cord-018142-xt71w4nr	177	4	have	have	VBP
cord-018142-xt71w4nr	177	5	an	an	DT
cord-018142-xt71w4nr	177	6	unpredictable	unpredictable	JJ
cord-018142-xt71w4nr	177	7	course	course	NN
cord-018142-xt71w4nr	177	8	.	.	.
cord-018142-xt71w4nr	178	1	All	all	DT
cord-018142-xt71w4nr	178	2	available	available	JJ
cord-018142-xt71w4nr	178	3	measures	measure	NNS
cord-018142-xt71w4nr	179	1	of`aggressive	of`aggressive	DT
cord-018142-xt71w4nr	179	2	intensive	intensive	JJ
cord-018142-xt71w4nr	179	3	care	care	NN
cord-018142-xt71w4nr	179	4	'	'	''
cord-018142-xt71w4nr	179	5	must	must	MD
cord-018142-xt71w4nr	179	6	,	,	,
cord-018142-xt71w4nr	179	7	therefore	therefore	RB
cord-018142-xt71w4nr	179	8	,	,	,
cord-018142-xt71w4nr	179	9	be	be	VB
cord-018142-xt71w4nr	179	10	proposed	propose	VBN
cord-018142-xt71w4nr	179	11	,	,	,
cord-018142-xt71w4nr	179	12	even	even	RB
cord-018142-xt71w4nr	179	13	in	in	IN
cord-018142-xt71w4nr	179	14	the	the	DT
cord-018142-xt71w4nr	179	15	case	case	NN
cord-018142-xt71w4nr	179	16	of	of	IN
cord-018142-xt71w4nr	179	17	severe	severe	JJ
cord-018142-xt71w4nr	179	18	neurological	neurological	JJ
cord-018142-xt71w4nr	179	19	signs	sign	NNS
cord-018142-xt71w4nr	179	20	.	.	.
cord-018142-xt71w4nr	180	1	Patients	patient	NNS
cord-018142-xt71w4nr	180	2	with	with	IN
cord-018142-xt71w4nr	180	3	respiratory	respiratory	JJ
cord-018142-xt71w4nr	180	4	failure	failure	NN
cord-018142-xt71w4nr	180	5	require	require	VBP
cord-018142-xt71w4nr	180	6	mechanical	mechanical	JJ
cord-018142-xt71w4nr	180	7	ventilation	ventilation	NN
cord-018142-xt71w4nr	180	8	.	.	.
cord-018142-xt71w4nr	181	1	This	this	DT
cord-018142-xt71w4nr	181	2	corresponds	correspond	VBZ
cord-018142-xt71w4nr	181	3	to	to	IN
cord-018142-xt71w4nr	181	4	59	59	CD
cord-018142-xt71w4nr	181	5	%	%	NN
cord-018142-xt71w4nr	181	6	of	of	IN
cord-018142-xt71w4nr	181	7	all	all	DT
cord-018142-xt71w4nr	181	8	patients	patient	NNS
cord-018142-xt71w4nr	181	9	admitted	admit	VBN
cord-018142-xt71w4nr	181	10	to	to	IN
cord-018142-xt71w4nr	181	11	the	the	DT
cord-018142-xt71w4nr	181	12	ICU	ICU	NNP
cord-018142-xt71w4nr	181	13	for	for	IN
cord-018142-xt71w4nr	181	14	TMA	TMA	NNP
cord-018142-xt71w4nr	181	15	[	[	-LRB-
cord-018142-xt71w4nr	181	16	11	11	CD
cord-018142-xt71w4nr	181	17	]	]	-RRB-
cord-018142-xt71w4nr	181	18	.	.	.
cord-018142-xt71w4nr	182	1	When	when	WRB
cord-018142-xt71w4nr	182	2	possible	possible	JJ
cord-018142-xt71w4nr	182	3	,	,	,
cord-018142-xt71w4nr	182	4	non	non	JJ
cord-018142-xt71w4nr	182	5	-	-	JJ
cord-018142-xt71w4nr	182	6	invasive	invasive	JJ
cord-018142-xt71w4nr	182	7	ventilation	ventilation	NN
cord-018142-xt71w4nr	182	8	should	should	MD
cord-018142-xt71w4nr	182	9	be	be	VB
cord-018142-xt71w4nr	182	10	preferred	prefer	VBN
cord-018142-xt71w4nr	182	11	to	to	IN
cord-018142-xt71w4nr	182	12	invasive	invasive	JJ
cord-018142-xt71w4nr	182	13	ventilation	ventilation	NN
cord-018142-xt71w4nr	182	14	due	due	IN
cord-018142-xt71w4nr	182	15	to	to	IN
cord-018142-xt71w4nr	182	16	the	the	DT
cord-018142-xt71w4nr	182	17	hemorrhagic	hemorrhagic	JJ
cord-018142-xt71w4nr	182	18	and	and	CC
cord-018142-xt71w4nr	182	19	infectious	infectious	JJ
cord-018142-xt71w4nr	182	20	risks	risk	NNS
cord-018142-xt71w4nr	182	21	associated	associate	VBN
cord-018142-xt71w4nr	182	22	with	with	IN
cord-018142-xt71w4nr	182	23	invasive	invasive	JJ
cord-018142-xt71w4nr	182	24	ventilation	ventilation	NN
cord-018142-xt71w4nr	182	25	.	.	.
cord-018142-xt71w4nr	183	1	Patients	patient	NNS
cord-018142-xt71w4nr	183	2	with	with	IN
cord-018142-xt71w4nr	183	3	severe	severe	JJ
cord-018142-xt71w4nr	183	4	renal	renal	JJ
cord-018142-xt71w4nr	183	5	failure	failure	NN
cord-018142-xt71w4nr	183	6	require	require	VBP
cord-018142-xt71w4nr	183	7	dialysis	dialysis	NN
cord-018142-xt71w4nr	183	8	(	(	-LRB-
cord-018142-xt71w4nr	183	9	47	47	CD
cord-018142-xt71w4nr	183	10	%	%	NN
cord-018142-xt71w4nr	183	11	of	of	IN
cord-018142-xt71w4nr	183	12	TMA	TMA	NNP
cord-018142-xt71w4nr	183	13	patients	patient	NNS
cord-018142-xt71w4nr	183	14	in	in	IN
cord-018142-xt71w4nr	183	15	intensive	intensive	JJ
cord-018142-xt71w4nr	183	16	care	care	NN
cord-018142-xt71w4nr	183	17	)	)	-RRB-
cord-018142-xt71w4nr	183	18	and	and	CC
cord-018142-xt71w4nr	184	1	32	32	CD
cord-018142-xt71w4nr	184	2	%	%	NN
cord-018142-xt71w4nr	184	3	of	of	IN
cord-018142-xt71w4nr	184	4	patients	patient	NNS
cord-018142-xt71w4nr	184	5	require	require	VBP
cord-018142-xt71w4nr	184	6	vasopressor	vasopressor	NN
cord-018142-xt71w4nr	184	7	support	support	NN
cord-018142-xt71w4nr	184	8	.	.	.
cord-018142-xt71w4nr	185	1	Hypertension	hypertension	NN
cord-018142-xt71w4nr	185	2	must	must	MD
cord-018142-xt71w4nr	185	3	also	also	RB
cord-018142-xt71w4nr	185	4	be	be	VB
cord-018142-xt71w4nr	185	5	treated	treat	VBN
cord-018142-xt71w4nr	185	6	,	,	,
cord-018142-xt71w4nr	185	7	preferably	preferably	RB
cord-018142-xt71w4nr	185	8	by	by	IN
cord-018142-xt71w4nr	185	9	angiotensin	angiotensin	NN
cord-018142-xt71w4nr	185	10	converting	convert	VBG
cord-018142-xt71w4nr	185	11	enzyme	enzyme	NN
cord-018142-xt71w4nr	185	12	(	(	-LRB-
cord-018142-xt71w4nr	185	13	ACE	ACE	NNP
cord-018142-xt71w4nr	185	14	)	)	-RRB-
cord-018142-xt71w4nr	185	15	inhibitors	inhibitor	NNS
cord-018142-xt71w4nr	185	16	.	.	.
cord-018142-xt71w4nr	186	1	The	the	DT
cord-018142-xt71w4nr	186	2	target	target	NN
cord-018142-xt71w4nr	186	3	blood	blood	NN
cord-018142-xt71w4nr	186	4	pressure	pressure	NN
cord-018142-xt71w4nr	186	5	is	be	VBZ
cord-018142-xt71w4nr	186	6	120/80	120/80	CD
cord-018142-xt71w4nr	186	7	mmHg	mmHg	NNS
cord-018142-xt71w4nr	186	8	.	.	.
cord-018142-xt71w4nr	187	1	Folate	folate	NN
cord-018142-xt71w4nr	187	2	supplementation	supplementation	NN
cord-018142-xt71w4nr	187	3	is	be	VBZ
cord-018142-xt71w4nr	187	4	systematically	systematically	RB
cord-018142-xt71w4nr	187	5	prescribed	prescribe	VBN
cord-018142-xt71w4nr	187	6	(	(	-LRB-
cord-018142-xt71w4nr	187	7	intense	intense	JJ
cord-018142-xt71w4nr	187	8	folate	folate	NN
cord-018142-xt71w4nr	187	9	-	-	HYPH
cord-018142-xt71w4nr	187	10	consuming	consume	VBG
cord-018142-xt71w4nr	187	11	bone	bone	NN
cord-018142-xt71w4nr	187	12	marrow	marrow	NN
cord-018142-xt71w4nr	187	13	regeneration	regeneration	NN
cord-018142-xt71w4nr	187	14	)	)	-RRB-
cord-018142-xt71w4nr	187	15	.	.	.
cord-018142-xt71w4nr	188	1	Anemia	anemia	NN
cord-018142-xt71w4nr	188	2	must	must	MD
cord-018142-xt71w4nr	188	3	be	be	VB
cord-018142-xt71w4nr	188	4	corrected	correct	VBN
cord-018142-xt71w4nr	188	5	by	by	IN
cord-018142-xt71w4nr	188	6	packed	pack	VBN
cord-018142-xt71w4nr	188	7	cell	cell	NN
cord-018142-xt71w4nr	188	8	transfusion	transfusion	NN
cord-018142-xt71w4nr	188	9	to	to	TO
cord-018142-xt71w4nr	188	10	achieve	achieve	VB
cord-018142-xt71w4nr	188	11	hemoglobin	hemoglobin	NN
cord-018142-xt71w4nr	188	12	concentrations	concentration	NNS
cord-018142-xt71w4nr	188	13	greater	great	JJR
cord-018142-xt71w4nr	188	14	than	than	IN
cord-018142-xt71w4nr	188	15	8	8	CD
cord-018142-xt71w4nr	189	1	g	g	NNP
cord-018142-xt71w4nr	189	2	/	/	SYM
cord-018142-xt71w4nr	189	3	dl	dl	NN
cord-018142-xt71w4nr	189	4	.	.	.
cord-018142-xt71w4nr	190	1	Platelet	platelet	NN
cord-018142-xt71w4nr	190	2	transfusions	transfusion	NNS
cord-018142-xt71w4nr	190	3	should	should	MD
cord-018142-xt71w4nr	190	4	be	be	VB
cord-018142-xt71w4nr	190	5	avoided	avoid	VBN
cord-018142-xt71w4nr	190	6	,	,	,
cord-018142-xt71w4nr	190	7	except	except	IN
cord-018142-xt71w4nr	190	8	in	in	IN
cord-018142-xt71w4nr	190	9	the	the	DT
cord-018142-xt71w4nr	190	10	case	case	NN
cord-018142-xt71w4nr	190	11	of	of	IN
cord-018142-xt71w4nr	190	12	uncontrolled	uncontrolled	JJ
cord-018142-xt71w4nr	190	13	bleeding	bleeding	NN
cord-018142-xt71w4nr	190	14	,	,	,
cord-018142-xt71w4nr	190	15	as	as	IN
cord-018142-xt71w4nr	190	16	they	-PRON-	PRP
cord-018142-xt71w4nr	190	17	may	may	MD
cord-018142-xt71w4nr	190	18	increase	increase	VB
cord-018142-xt71w4nr	190	19	the	the	DT
cord-018142-xt71w4nr	190	20	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	190	21	process	process	NN
cord-018142-xt71w4nr	190	22	in	in	IN
cord-018142-xt71w4nr	190	23	the	the	DT
cord-018142-xt71w4nr	190	24	microcirculation	microcirculation	NN
cord-018142-xt71w4nr	190	25	.	.	.
cord-018142-xt71w4nr	191	1	Anticonvulsants	anticonvulsant	NNS
cord-018142-xt71w4nr	191	2	should	should	MD
cord-018142-xt71w4nr	191	3	be	be	VB
cord-018142-xt71w4nr	191	4	prescribed	prescribe	VBN
cord-018142-xt71w4nr	191	5	to	to	IN
cord-018142-xt71w4nr	191	6	patients	patient	NNS
cord-018142-xt71w4nr	191	7	with	with	IN
cord-018142-xt71w4nr	191	8	a	a	DT
cord-018142-xt71w4nr	191	9	history	history	NN
cord-018142-xt71w4nr	191	10	of	of	IN
cord-018142-xt71w4nr	191	11	epilepsy	epilepsy	NN
cord-018142-xt71w4nr	191	12	.	.	.
cord-018142-xt71w4nr	192	1	Any	any	DT
cord-018142-xt71w4nr	192	2	triggering	trigger	VBG
cord-018142-xt71w4nr	192	3	or	or	CC
cord-018142-xt71w4nr	192	4	associated	associated	JJ
cord-018142-xt71w4nr	192	5	factors	factor	NNS
cord-018142-xt71w4nr	192	6	must	must	MD
cord-018142-xt71w4nr	192	7	be	be	VB
cord-018142-xt71w4nr	192	8	treated	treat	VBN
cord-018142-xt71w4nr	192	9	.	.	.
cord-018142-xt71w4nr	193	1	In	in	IN
cord-018142-xt71w4nr	193	2	particular	particular	JJ
cord-018142-xt71w4nr	193	3	,	,	,
cord-018142-xt71w4nr	193	4	antibiotics	antibiotic	NNS
cord-018142-xt71w4nr	193	5	should	should	MD
cord-018142-xt71w4nr	193	6	be	be	VB
cord-018142-xt71w4nr	193	7	initiated	initiate	VBN
cord-018142-xt71w4nr	193	8	whenever	whenever	WRB
cord-018142-xt71w4nr	193	9	an	an	DT
cord-018142-xt71w4nr	193	10	infection	infection	NN
cord-018142-xt71w4nr	193	11	is	be	VBZ
cord-018142-xt71w4nr	193	12	suspected	suspect	VBN
cord-018142-xt71w4nr	193	13	(	(	-LRB-
cord-018142-xt71w4nr	193	14	except	except	IN
cord-018142-xt71w4nr	193	15	for	for	IN
cord-018142-xt71w4nr	193	16	cases	case	NNS
cord-018142-xt71w4nr	193	17	of	of	IN
cord-018142-xt71w4nr	193	18	post	post	JJ
cord-018142-xt71w4nr	193	19	-	-	JJ
cord-018142-xt71w4nr	193	20	diarrheal	diarrheal	JJ
cord-018142-xt71w4nr	193	21	HUS	HUS	NNP
cord-018142-xt71w4nr	193	22	,	,	,
cord-018142-xt71w4nr	193	23	in	in	IN
cord-018142-xt71w4nr	193	24	which	which	WDT
cord-018142-xt71w4nr	193	25	antibiotics	antibiotic	NNS
cord-018142-xt71w4nr	193	26	can	can	MD
cord-018142-xt71w4nr	193	27	worsen	worsen	VB
cord-018142-xt71w4nr	193	28	the	the	DT
cord-018142-xt71w4nr	193	29	HUS	HUS	NNP
cord-018142-xt71w4nr	193	30	[	[	-LRB-
cord-018142-xt71w4nr	193	31	37	37	CD
cord-018142-xt71w4nr	193	32	]	]	-RRB-
cord-018142-xt71w4nr	193	33	)	)	-RRB-
cord-018142-xt71w4nr	193	34	.	.	.
cord-018142-xt71w4nr	194	1	Persistence	persistence	NN
cord-018142-xt71w4nr	194	2	of	of	IN
cord-018142-xt71w4nr	194	3	an	an	DT
cord-018142-xt71w4nr	194	4	occult	occult	JJ
cord-018142-xt71w4nr	194	5	bacterial	bacterial	JJ
cord-018142-xt71w4nr	194	6	infection	infection	NN
cord-018142-xt71w4nr	194	7	can	can	MD
cord-018142-xt71w4nr	194	8	lead	lead	VB
cord-018142-xt71w4nr	194	9	to	to	IN
cord-018142-xt71w4nr	194	10	persistence	persistence	NN
cord-018142-xt71w4nr	194	11	of	of	IN
cord-018142-xt71w4nr	194	12	TTP	TTP	NNP
cord-018142-xt71w4nr	194	13	,	,	,
cord-018142-xt71w4nr	194	14	making	make	VBG
cord-018142-xt71w4nr	194	15	it	-PRON-	PRP
cord-018142-xt71w4nr	194	16	refractory	refractory	JJ
cord-018142-xt71w4nr	194	17	to	to	IN
cord-018142-xt71w4nr	194	18	conventional	conventional	JJ
cord-018142-xt71w4nr	194	19	treatment	treatment	NN
cord-018142-xt71w4nr	194	20	.	.	.
cord-018142-xt71w4nr	195	1	Indication	indication	NN
cord-018142-xt71w4nr	195	2	.	.	.
cord-018142-xt71w4nr	196	1	This	this	DT
cord-018142-xt71w4nr	196	2	treatment	treatment	NN
cord-018142-xt71w4nr	196	3	is	be	VBZ
cord-018142-xt71w4nr	196	4	not	not	RB
cord-018142-xt71w4nr	196	5	indicated	indicate	VBN
cord-018142-xt71w4nr	196	6	in	in	IN
cord-018142-xt71w4nr	196	7	post	post	JJ
cord-018142-xt71w4nr	196	8	-	-	JJ
cord-018142-xt71w4nr	196	9	diarrheal	diarrheal	JJ
cord-018142-xt71w4nr	196	10	HUS	HUS	NNP
cord-018142-xt71w4nr	196	11	,	,	,
cord-018142-xt71w4nr	196	12	as	as	IN
cord-018142-xt71w4nr	196	13	plasma	plasma	NN
cord-018142-xt71w4nr	196	14	therapy	therapy	NN
cord-018142-xt71w4nr	196	15	does	do	VBZ
cord-018142-xt71w4nr	196	16	not	not	RB
cord-018142-xt71w4nr	196	17	modify	modify	VB
cord-018142-xt71w4nr	196	18	survival	survival	NN
cord-018142-xt71w4nr	196	19	(	(	-LRB-
cord-018142-xt71w4nr	196	20	which	which	WDT
cord-018142-xt71w4nr	196	21	is	be	VBZ
cord-018142-xt71w4nr	196	22	excellent	excellent	JJ
cord-018142-xt71w4nr	196	23	in	in	IN
cord-018142-xt71w4nr	196	24	response	response	NN
cord-018142-xt71w4nr	196	25	to	to	IN
cord-018142-xt71w4nr	196	26	symptomatic	symptomatic	JJ
cord-018142-xt71w4nr	196	27	treatment	treatment	NN
cord-018142-xt71w4nr	196	28	alone	alone	RB
cord-018142-xt71w4nr	196	29	)	)	-RRB-
cord-018142-xt71w4nr	196	30	.	.	.
cord-018142-xt71w4nr	197	1	Plasma	plasma	NN
cord-018142-xt71w4nr	197	2	therapy	therapy	NN
cord-018142-xt71w4nr	197	3	must	must	MD
cord-018142-xt71w4nr	197	4	be	be	VB
cord-018142-xt71w4nr	197	5	urgently	urgently	RB
cord-018142-xt71w4nr	197	6	initiated	initiate	VBN
cord-018142-xt71w4nr	197	7	in	in	IN
cord-018142-xt71w4nr	197	8	patients	patient	NNS
cord-018142-xt71w4nr	197	9	with	with	IN
cord-018142-xt71w4nr	197	10	TTP	TTP	NNP
cord-018142-xt71w4nr	197	11	,	,	,
cord-018142-xt71w4nr	197	12	as	as	IN
cord-018142-xt71w4nr	197	13	its	-PRON-	PRP$
cord-018142-xt71w4nr	197	14	efficacy	efficacy	NN
cord-018142-xt71w4nr	197	15	in	in	IN
cord-018142-xt71w4nr	197	16	terms	term	NNS
cord-018142-xt71w4nr	197	17	of	of	IN
cord-018142-xt71w4nr	197	18	survival	survival	NN
cord-018142-xt71w4nr	197	19	has	have	VBZ
cord-018142-xt71w4nr	197	20	been	be	VBN
cord-018142-xt71w4nr	197	21	demonstrated	demonstrate	VBN
cord-018142-xt71w4nr	197	22	.	.	.
cord-018142-xt71w4nr	198	1	Plasma	plasma	NN
cord-018142-xt71w4nr	198	2	therapy	therapy	NN
cord-018142-xt71w4nr	198	3	is	be	VBZ
cord-018142-xt71w4nr	198	4	used	use	VBN
cord-018142-xt71w4nr	198	5	in	in	IN
cord-018142-xt71w4nr	198	6	adults	adult	NNS
cord-018142-xt71w4nr	198	7	with	with	IN
cord-018142-xt71w4nr	198	8	HUS	HUS	NNP
cord-018142-xt71w4nr	198	9	by	by	IN
cord-018142-xt71w4nr	198	10	analogy	analogy	NN
cord-018142-xt71w4nr	198	11	with	with	IN
cord-018142-xt71w4nr	198	12	the	the	DT
cord-018142-xt71w4nr	198	13	management	management	NN
cord-018142-xt71w4nr	198	14	with	with	IN
cord-018142-xt71w4nr	198	15	TTP	TTP	NNP
cord-018142-xt71w4nr	198	16	,	,	,
cord-018142-xt71w4nr	198	17	although	although	IN
cord-018142-xt71w4nr	198	18	no	no	DT
cord-018142-xt71w4nr	198	19	studies	study	NNS
cord-018142-xt71w4nr	198	20	are	be	VBP
cord-018142-xt71w4nr	198	21	in	in	IN
cord-018142-xt71w4nr	198	22	favor	favor	NN
cord-018142-xt71w4nr	198	23	of	of	IN
cord-018142-xt71w4nr	198	24	either	either	DT
cord-018142-xt71w4nr	198	25	plasma	plasma	NN
cord-018142-xt71w4nr	198	26	exchange	exchange	NN
cord-018142-xt71w4nr	198	27	or	or	CC
cord-018142-xt71w4nr	198	28	FFP	FFP	NNP
cord-018142-xt71w4nr	198	29	transfusion	transfusion	NN
cord-018142-xt71w4nr	198	30	.	.	.
cord-018142-xt71w4nr	199	1	It	-PRON-	PRP
cord-018142-xt71w4nr	199	2	is	be	VBZ
cord-018142-xt71w4nr	199	3	essential	essential	JJ
cord-018142-xt71w4nr	199	4	to	to	TO
cord-018142-xt71w4nr	199	5	control	control	VB
cord-018142-xt71w4nr	199	6	underlying	underlying	JJ
cord-018142-xt71w4nr	199	7	predisposing	predispose	VBG
cord-018142-xt71w4nr	199	8	factors	factor	NNS
cord-018142-xt71w4nr	199	9	.	.	.
cord-018142-xt71w4nr	200	1	Fresh	fresh	JJ
cord-018142-xt71w4nr	200	2	frozen	frozen	JJ
cord-018142-xt71w4nr	200	3	plasma	plasma	NN
cord-018142-xt71w4nr	200	4	transfusion	transfusion	NN
cord-018142-xt71w4nr	200	5	or	or	CC
cord-018142-xt71w4nr	200	6	plasma	plasma	NN
cord-018142-xt71w4nr	200	7	exchange	exchange	NN
cord-018142-xt71w4nr	200	8	?	?	.
cord-018142-xt71w4nr	201	1	Recent	recent	JJ
cord-018142-xt71w4nr	201	2	studies	study	NNS
cord-018142-xt71w4nr	201	3	have	have	VBP
cord-018142-xt71w4nr	201	4	demonstrated	demonstrate	VBN
cord-018142-xt71w4nr	201	5	the	the	DT
cord-018142-xt71w4nr	201	6	superiority	superiority	NN
cord-018142-xt71w4nr	201	7	of	of	IN
cord-018142-xt71w4nr	201	8	plasma	plasma	NN
cord-018142-xt71w4nr	201	9	exchange	exchange	NN
cord-018142-xt71w4nr	201	10	over	over	IN
cord-018142-xt71w4nr	201	11	FFP	FFP	NNP
cord-018142-xt71w4nr	201	12	transfusion	transfusion	NN
cord-018142-xt71w4nr	201	13	in	in	IN
cord-018142-xt71w4nr	201	14	terms	term	NNS
cord-018142-xt71w4nr	201	15	of	of	IN
cord-018142-xt71w4nr	201	16	survival	survival	NN
cord-018142-xt71w4nr	201	17	and	and	CC
cord-018142-xt71w4nr	201	18	response	response	NN
cord-018142-xt71w4nr	201	19	to	to	IN
cord-018142-xt71w4nr	201	20	treatment	treatment	NN
cord-018142-xt71w4nr	201	21	of	of	IN
cord-018142-xt71w4nr	201	22	TTP	TTP	NNP
cord-018142-xt71w4nr	201	23	[	[	-LRB-
cord-018142-xt71w4nr	201	24	36	36	CD
cord-018142-xt71w4nr	201	25	]	]	-RRB-
cord-018142-xt71w4nr	201	26	.	.	.
cord-018142-xt71w4nr	202	1	The	the	DT
cord-018142-xt71w4nr	202	2	use	use	NN
cord-018142-xt71w4nr	202	3	of	of	IN
cord-018142-xt71w4nr	202	4	plasma	plasma	NN
cord-018142-xt71w4nr	202	5	exchange	exchange	NN
cord-018142-xt71w4nr	202	6	is	be	VBZ
cord-018142-xt71w4nr	202	7	independently	independently	RB
cord-018142-xt71w4nr	202	8	correlated	correlate	VBN
cord-018142-xt71w4nr	202	9	with	with	IN
cord-018142-xt71w4nr	202	10	survival	survival	NN
cord-018142-xt71w4nr	202	11	.	.	.
cord-018142-xt71w4nr	203	1	The	the	DT
cord-018142-xt71w4nr	203	2	efficacy	efficacy	NN
cord-018142-xt71w4nr	203	3	of	of	IN
cord-018142-xt71w4nr	203	4	plasma	plasma	NN
cord-018142-xt71w4nr	203	5	exchange	exchange	NN
cord-018142-xt71w4nr	203	6	depends	depend	VBZ
cord-018142-xt71w4nr	203	7	on	on	IN
cord-018142-xt71w4nr	203	8	the	the	DT
cord-018142-xt71w4nr	203	9	volume	volume	NN
cord-018142-xt71w4nr	203	10	of	of	IN
cord-018142-xt71w4nr	203	11	plasma	plasma	NN
cord-018142-xt71w4nr	203	12	administered	administer	VBN
cord-018142-xt71w4nr	203	13	to	to	IN
cord-018142-xt71w4nr	203	14	the	the	DT
cord-018142-xt71w4nr	203	15	patient	patient	NN
cord-018142-xt71w4nr	203	16	(	(	-LRB-
cord-018142-xt71w4nr	203	17	plasma	plasma	NN
cord-018142-xt71w4nr	203	18	exchange	exchange	NN
cord-018142-xt71w4nr	203	19	is	be	VBZ
cord-018142-xt71w4nr	203	20	able	able	JJ
cord-018142-xt71w4nr	203	21	to	to	TO
cord-018142-xt71w4nr	203	22	administer	administer	VB
cord-018142-xt71w4nr	203	23	three	three	CD
cord-018142-xt71w4nr	203	24	times	time	NNS
cord-018142-xt71w4nr	203	25	more	more	JJR
cord-018142-xt71w4nr	203	26	plasma	plasma	NN
cord-018142-xt71w4nr	203	27	than	than	IN
cord-018142-xt71w4nr	203	28	FFP	FFP	NNP
cord-018142-xt71w4nr	203	29	transfusion	transfusion	NN
cord-018142-xt71w4nr	203	30	alone	alone	RB
cord-018142-xt71w4nr	203	31	[	[	-LRB-
cord-018142-xt71w4nr	203	32	11	11	CD
cord-018142-xt71w4nr	203	33	]	]	-RRB-
cord-018142-xt71w4nr	203	34	)	)	-RRB-
cord-018142-xt71w4nr	203	35	.	.	.
cord-018142-xt71w4nr	204	1	Two	two	CD
cord-018142-xt71w4nr	204	2	pathophysiological	pathophysiological	JJ
cord-018142-xt71w4nr	204	3	mechanisms	mechanism	NNS
cord-018142-xt71w4nr	204	4	can	can	MD
cord-018142-xt71w4nr	204	5	explain	explain	VB
cord-018142-xt71w4nr	204	6	the	the	DT
cord-018142-xt71w4nr	204	7	efficacy	efficacy	NN
cord-018142-xt71w4nr	204	8	of	of	IN
cord-018142-xt71w4nr	204	9	plasma	plasma	NN
cord-018142-xt71w4nr	204	10	exchange	exchange	NN
cord-018142-xt71w4nr	204	11	:	:	:
cord-018142-xt71w4nr	204	12	plasma	plasma	NN
cord-018142-xt71w4nr	204	13	exchange	exchange	NN
cord-018142-xt71w4nr	204	14	removes	remove	VBZ
cord-018142-xt71w4nr	204	15	a`pathogenic	a`pathogenic	DT
cord-018142-xt71w4nr	204	16	'	'	``
cord-018142-xt71w4nr	204	17	component	component	NN
cord-018142-xt71w4nr	204	18	from	from	IN
cord-018142-xt71w4nr	204	19	the	the	DT
cord-018142-xt71w4nr	204	20	patient	patient	NN
cord-018142-xt71w4nr	204	21	's	's	POS
cord-018142-xt71w4nr	204	22	plasma	plasma	NN
cord-018142-xt71w4nr	204	23	(	(	-LRB-
cord-018142-xt71w4nr	204	24	ULvWF	ULvWF	NNP
cord-018142-xt71w4nr	204	25	or	or	CC
cord-018142-xt71w4nr	204	26	auto	auto	NN
cord-018142-xt71w4nr	204	27	-	-	HYPH
cord-018142-xt71w4nr	204	28	antibodies	antibody	NNS
cord-018142-xt71w4nr	204	29	)	)	-RRB-
cord-018142-xt71w4nr	204	30	and	and	CC
cord-018142-xt71w4nr	204	31	compensates	compensate	VBZ
cord-018142-xt71w4nr	204	32	for	for	IN
cord-018142-xt71w4nr	204	33	the	the	DT
cord-018142-xt71w4nr	204	34	deficient	deficient	JJ
cord-018142-xt71w4nr	204	35	protease	protease	NN
cord-018142-xt71w4nr	204	36	(	(	-LRB-
cord-018142-xt71w4nr	204	37	by	by	IN
cord-018142-xt71w4nr	204	38	providing	provide	VBG
cord-018142-xt71w4nr	204	39	large	large	JJ
cord-018142-xt71w4nr	204	40	quantities	quantity	NNS
cord-018142-xt71w4nr	204	41	of	of	IN
cord-018142-xt71w4nr	204	42	plasma	plasma	NN
cord-018142-xt71w4nr	204	43	)	)	-RRB-
cord-018142-xt71w4nr	204	44	.	.	.
cord-018142-xt71w4nr	205	1	In	in	IN
cord-018142-xt71w4nr	205	2	cases	case	NNS
cord-018142-xt71w4nr	205	3	of	of	IN
cord-018142-xt71w4nr	205	4	TTP	TTP	NNP
cord-018142-xt71w4nr	205	5	not	not	RB
cord-018142-xt71w4nr	205	6	associated	associate	VBN
cord-018142-xt71w4nr	205	7	with	with	IN
cord-018142-xt71w4nr	205	8	an	an	DT
cord-018142-xt71w4nr	205	9	inhibitor	inhibitor	NN
cord-018142-xt71w4nr	205	10	,	,	,
cord-018142-xt71w4nr	205	11	FFP	FFP	NNP
cord-018142-xt71w4nr	205	12	transfusions	transfusion	NNS
cord-018142-xt71w4nr	205	13	may	may	MD
cord-018142-xt71w4nr	205	14	be	be	VB
cord-018142-xt71w4nr	205	15	sufficient	sufficient	JJ
cord-018142-xt71w4nr	205	16	.	.	.
cord-018142-xt71w4nr	206	1	When	when	WRB
cord-018142-xt71w4nr	206	2	plasma	plasma	NN
cord-018142-xt71w4nr	206	3	exchange	exchange	NN
cord-018142-xt71w4nr	206	4	can	can	MD
cord-018142-xt71w4nr	206	5	not	not	RB
cord-018142-xt71w4nr	206	6	be	be	VB
cord-018142-xt71w4nr	206	7	started	start	VBN
cord-018142-xt71w4nr	206	8	immediately	immediately	RB
cord-018142-xt71w4nr	206	9	(	(	-LRB-
cord-018142-xt71w4nr	206	10	for	for	IN
cord-018142-xt71w4nr	206	11	technical	technical	JJ
cord-018142-xt71w4nr	206	12	reasons	reason	NNS
cord-018142-xt71w4nr	206	13	,	,	,
cord-018142-xt71w4nr	206	14	or	or	CC
cord-018142-xt71w4nr	206	15	while	while	IN
cord-018142-xt71w4nr	206	16	waiting	wait	VBG
cord-018142-xt71w4nr	206	17	for	for	IN
cord-018142-xt71w4nr	206	18	transfer	transfer	NN
cord-018142-xt71w4nr	206	19	to	to	IN
cord-018142-xt71w4nr	206	20	a	a	DT
cord-018142-xt71w4nr	206	21	specialized	specialized	JJ
cord-018142-xt71w4nr	206	22	center	center	NN
cord-018142-xt71w4nr	206	23	)	)	-RRB-
cord-018142-xt71w4nr	206	24	,	,	,
cord-018142-xt71w4nr	206	25	large	large	JJ
cord-018142-xt71w4nr	206	26	-	-	HYPH
cord-018142-xt71w4nr	206	27	volume	volume	NN
cord-018142-xt71w4nr	206	28	FFP	FFP	NNP
cord-018142-xt71w4nr	206	29	transfusion	transfusion	NN
cord-018142-xt71w4nr	206	30	(	(	-LRB-
cord-018142-xt71w4nr	206	31	20	20	CD
cord-018142-xt71w4nr	206	32	to	to	TO
cord-018142-xt71w4nr	206	33	30	30	CD
cord-018142-xt71w4nr	206	34	ml	ml	NNS
cord-018142-xt71w4nr	206	35	/	/	SYM
cord-018142-xt71w4nr	206	36	kg	kg	NNP
cord-018142-xt71w4nr	206	37	/	/	SYM
cord-018142-xt71w4nr	206	38	day	day	NN
cord-018142-xt71w4nr	206	39	)	)	-RRB-
cord-018142-xt71w4nr	206	40	can	can	MD
cord-018142-xt71w4nr	206	41	be	be	VB
cord-018142-xt71w4nr	206	42	started	start	VBN
cord-018142-xt71w4nr	206	43	prior	prior	RB
cord-018142-xt71w4nr	206	44	to	to	IN
cord-018142-xt71w4nr	206	45	plasma	plasma	NN
cord-018142-xt71w4nr	206	46	exchange	exchange	NN
cord-018142-xt71w4nr	206	47	,	,	,
cord-018142-xt71w4nr	206	48	but	but	CC
cord-018142-xt71w4nr	206	49	it	-PRON-	PRP
cord-018142-xt71w4nr	206	50	is	be	VBZ
cord-018142-xt71w4nr	206	51	associated	associate	VBN
cord-018142-xt71w4nr	206	52	with	with	IN
cord-018142-xt71w4nr	206	53	a	a	DT
cord-018142-xt71w4nr	206	54	risk	risk	NN
cord-018142-xt71w4nr	206	55	of	of	IN
cord-018142-xt71w4nr	206	56	fluid	fluid	JJ
cord-018142-xt71w4nr	206	57	overload	overload	NN
cord-018142-xt71w4nr	206	58	,	,	,
cord-018142-xt71w4nr	206	59	protein	protein	NN
cord-018142-xt71w4nr	206	60	-	-	HYPH
cord-018142-xt71w4nr	206	61	overload	overload	NN
cord-018142-xt71w4nr	206	62	proteinuria	proteinuria	NN
cord-018142-xt71w4nr	206	63	,	,	,
cord-018142-xt71w4nr	206	64	hyperproteinemia	hyperproteinemia	NN
cord-018142-xt71w4nr	206	65	,	,	,
cord-018142-xt71w4nr	206	66	and	and	CC
cord-018142-xt71w4nr	206	67	hyperviscosity	hyperviscosity	NN
cord-018142-xt71w4nr	206	68	syndrome	syndrome	NN
cord-018142-xt71w4nr	206	69	.	.	.
cord-018142-xt71w4nr	207	1	The	the	DT
cord-018142-xt71w4nr	207	2	raised	raise	VBN
cord-018142-xt71w4nr	207	3	oncotic	oncotic	JJ
cord-018142-xt71w4nr	207	4	pressure	pressure	NN
cord-018142-xt71w4nr	207	5	can	can	MD
cord-018142-xt71w4nr	207	6	also	also	RB
cord-018142-xt71w4nr	207	7	accentuate	accentuate	VB
cord-018142-xt71w4nr	207	8	renal	renal	JJ
cord-018142-xt71w4nr	207	9	insufficiency	insufficiency	NN
cord-018142-xt71w4nr	207	10	.	.	.
cord-018142-xt71w4nr	208	1	The	the	DT
cord-018142-xt71w4nr	208	2	plasma	plasma	NN
cord-018142-xt71w4nr	208	3	exchange	exchange	NN
cord-018142-xt71w4nr	208	4	technique	technique	NN
cord-018142-xt71w4nr	208	5	is	be	VBZ
cord-018142-xt71w4nr	208	6	based	base	VBN
cord-018142-xt71w4nr	208	7	on	on	IN
cord-018142-xt71w4nr	208	8	the	the	DT
cord-018142-xt71w4nr	208	9	daily	daily	JJ
cord-018142-xt71w4nr	208	10	exchange	exchange	NN
cord-018142-xt71w4nr	208	11	of	of	IN
cord-018142-xt71w4nr	208	12	one	one	CD
cord-018142-xt71w4nr	208	13	to	to	TO
cord-018142-xt71w4nr	208	14	two	two	CD
cord-018142-xt71w4nr	208	15	plasma	plasma	NN
cord-018142-xt71w4nr	208	16	masses	masse	NNS
cord-018142-xt71w4nr	208	17	fully	fully	RB
cord-018142-xt71w4nr	208	18	compensated	compensate	VBN
cord-018142-xt71w4nr	208	19	by	by	IN
cord-018142-xt71w4nr	208	20	FFP	FFP	NNP
cord-018142-xt71w4nr	208	21	.	.	.
cord-018142-xt71w4nr	209	1	A	a	DT
cord-018142-xt71w4nr	209	2	plasma	plasma	NN
cord-018142-xt71w4nr	209	3	exchange	exchange	NN
cord-018142-xt71w4nr	209	4	session	session	NN
cord-018142-xt71w4nr	209	5	lasts	last	VBZ
cord-018142-xt71w4nr	209	6	about	about	RB
cord-018142-xt71w4nr	209	7	3	3	CD
cord-018142-xt71w4nr	209	8	hours	hour	NNS
cord-018142-xt71w4nr	209	9	for	for	IN
cord-018142-xt71w4nr	209	10	50	50	CD
cord-018142-xt71w4nr	209	11	to	to	TO
cord-018142-xt71w4nr	209	12	80	80	CD
cord-018142-xt71w4nr	209	13	ml	ml	NNS
cord-018142-xt71w4nr	209	14	/	/	SYM
cord-018142-xt71w4nr	209	15	kg	kg	NNS
cord-018142-xt71w4nr	209	16	of	of	IN
cord-018142-xt71w4nr	209	17	FFP	FFP	NNP
cord-018142-xt71w4nr	209	18	.	.	.
cord-018142-xt71w4nr	210	1	It	-PRON-	PRP
cord-018142-xt71w4nr	210	2	is	be	VBZ
cord-018142-xt71w4nr	210	3	performed	perform	VBN
cord-018142-xt71w4nr	210	4	via	via	IN
cord-018142-xt71w4nr	210	5	a	a	DT
cord-018142-xt71w4nr	210	6	central	central	JJ
cord-018142-xt71w4nr	210	7	venous	venous	JJ
cord-018142-xt71w4nr	210	8	catheter	catheter	NN
cord-018142-xt71w4nr	210	9	,	,	,
cord-018142-xt71w4nr	210	10	rarely	rarely	RB
cord-018142-xt71w4nr	210	11	placed	place	VBN
cord-018142-xt71w4nr	210	12	in	in	IN
cord-018142-xt71w4nr	210	13	a	a	DT
cord-018142-xt71w4nr	210	14	subclavian	subclavian	JJ
cord-018142-xt71w4nr	210	15	vein	vein	NN
cord-018142-xt71w4nr	210	16	due	due	IN
cord-018142-xt71w4nr	210	17	to	to	IN
cord-018142-xt71w4nr	210	18	the	the	DT
cord-018142-xt71w4nr	210	19	risk	risk	NN
cord-018142-xt71w4nr	210	20	of	of	IN
cord-018142-xt71w4nr	210	21	bleeding	bleed	VBG
cord-018142-xt71w4nr	210	22	,	,	,
cord-018142-xt71w4nr	210	23	and	and	CC
cord-018142-xt71w4nr	210	24	requires	require	VBZ
cord-018142-xt71w4nr	210	25	anticoagulation	anticoagulation	NN
cord-018142-xt71w4nr	210	26	at	at	IN
cord-018142-xt71w4nr	210	27	effective	effective	JJ
cord-018142-xt71w4nr	210	28	doses	dose	NNS
cord-018142-xt71w4nr	210	29	during	during	IN
cord-018142-xt71w4nr	210	30	the	the	DT
cord-018142-xt71w4nr	210	31	session	session	NN
cord-018142-xt71w4nr	210	32	.	.	.
cord-018142-xt71w4nr	211	1	A	a	DT
cord-018142-xt71w4nr	211	2	systematic	systematic	JJ
cord-018142-xt71w4nr	211	3	calcium	calcium	NN
cord-018142-xt71w4nr	211	4	supplement	supplement	NN
cord-018142-xt71w4nr	211	5	is	be	VBZ
cord-018142-xt71w4nr	211	6	started	start	VBN
cord-018142-xt71w4nr	211	7	during	during	IN
cord-018142-xt71w4nr	211	8	plasma	plasma	NN
cord-018142-xt71w4nr	211	9	exchange	exchange	NN
cord-018142-xt71w4nr	211	10	(	(	-LRB-
cord-018142-xt71w4nr	211	11	risk	risk	NN
cord-018142-xt71w4nr	211	12	of	of	IN
cord-018142-xt71w4nr	211	13	hypocalcemia	hypocalcemia	NN
cord-018142-xt71w4nr	211	14	due	due	IN
cord-018142-xt71w4nr	211	15	to	to	IN
cord-018142-xt71w4nr	211	16	the	the	DT
cord-018142-xt71w4nr	211	17	toxicity	toxicity	NN
cord-018142-xt71w4nr	211	18	of	of	IN
cord-018142-xt71w4nr	211	19	citrate	citrate	NN
cord-018142-xt71w4nr	211	20	)	)	-RRB-
cord-018142-xt71w4nr	211	21	.	.	.
cord-018142-xt71w4nr	212	1	Plasma	plasma	NN
cord-018142-xt71w4nr	212	2	exchange	exchange	NN
cord-018142-xt71w4nr	212	3	is	be	VBZ
cord-018142-xt71w4nr	212	4	time	time	NN
cord-018142-xt71w4nr	212	5	-	-	HYPH
cord-018142-xt71w4nr	212	6	consuming	consume	VBG
cord-018142-xt71w4nr	212	7	,	,	,
cord-018142-xt71w4nr	212	8	expensive	expensive	JJ
cord-018142-xt71w4nr	212	9	and	and	CC
cord-018142-xt71w4nr	212	10	invasive	invasive	JJ
cord-018142-xt71w4nr	212	11	and	and	CC
cord-018142-xt71w4nr	212	12	carries	carry	VBZ
cord-018142-xt71w4nr	212	13	a	a	DT
cord-018142-xt71w4nr	212	14	risk	risk	NN
cord-018142-xt71w4nr	212	15	of	of	IN
cord-018142-xt71w4nr	212	16	immunological	immunological	JJ
cord-018142-xt71w4nr	212	17	pulmonary	pulmonary	JJ
cord-018142-xt71w4nr	212	18	edema	edema	NN
cord-018142-xt71w4nr	212	19	(	(	-LRB-
cord-018142-xt71w4nr	212	20	almost	almost	RB
cord-018142-xt71w4nr	212	21	eliminated	eliminate	VBN
cord-018142-xt71w4nr	212	22	by	by	IN
cord-018142-xt71w4nr	212	23	solvent	solvent	NN
cord-018142-xt71w4nr	212	24	/	/	SYM
cord-018142-xt71w4nr	212	25	detergenttreated	detergenttreated	JJ
cord-018142-xt71w4nr	212	26	plasma	plasma	NN
cord-018142-xt71w4nr	212	27	)	)	-RRB-
cord-018142-xt71w4nr	212	28	.	.	.
cord-018142-xt71w4nr	213	1	The	the	DT
cord-018142-xt71w4nr	213	2	duration	duration	NN
cord-018142-xt71w4nr	213	3	of	of	IN
cord-018142-xt71w4nr	213	4	treatment	treatment	NN
cord-018142-xt71w4nr	213	5	is	be	VBZ
cord-018142-xt71w4nr	213	6	variable	variable	JJ
cord-018142-xt71w4nr	213	7	.	.	.
cord-018142-xt71w4nr	214	1	Plasma	plasma	NN
cord-018142-xt71w4nr	214	2	exchange	exchange	NN
cord-018142-xt71w4nr	214	3	is	be	VBZ
cord-018142-xt71w4nr	214	4	continued	continue	VBN
cord-018142-xt71w4nr	214	5	daily	daily	RB
cord-018142-xt71w4nr	214	6	until	until	IN
cord-018142-xt71w4nr	214	7	restoration	restoration	NN
cord-018142-xt71w4nr	214	8	of	of	IN
cord-018142-xt71w4nr	214	9	a	a	DT
cord-018142-xt71w4nr	214	10	normal	normal	JJ
cord-018142-xt71w4nr	214	11	platelet	platelet	NN
cord-018142-xt71w4nr	214	12	count	count	NN
cord-018142-xt71w4nr	214	13	(	(	-LRB-
cord-018142-xt71w4nr	214	14	>	>	NFP
cord-018142-xt71w4nr	214	15	150,000	150,000	CD
cord-018142-xt71w4nr	214	16	/	/	SYM
cord-018142-xt71w4nr	214	17	mm	mm	NN
cord-018142-xt71w4nr	214	18	3	3	CD
cord-018142-xt71w4nr	214	19	)	)	-RRB-
cord-018142-xt71w4nr	214	20	for	for	IN
cord-018142-xt71w4nr	214	21	at	at	RB
cord-018142-xt71w4nr	214	22	least	least	RBS
cord-018142-xt71w4nr	214	23	48	48	CD
cord-018142-xt71w4nr	214	24	hours	hour	NNS
cord-018142-xt71w4nr	214	25	with	with	IN
cord-018142-xt71w4nr	214	26	a	a	DT
cord-018142-xt71w4nr	214	27	reduction	reduction	NN
cord-018142-xt71w4nr	214	28	in	in	IN
cord-018142-xt71w4nr	214	29	LDH	LDH	NNP
cord-018142-xt71w4nr	214	30	levels	level	NNS
cord-018142-xt71w4nr	214	31	and	and	CC
cord-018142-xt71w4nr	214	32	reticulocyte	reticulocyte	NN
cord-018142-xt71w4nr	214	33	counts	count	NNS
cord-018142-xt71w4nr	214	34	.	.	.
cord-018142-xt71w4nr	215	1	The	the	DT
cord-018142-xt71w4nr	215	2	frequency	frequency	NN
cord-018142-xt71w4nr	215	3	of	of	IN
cord-018142-xt71w4nr	215	4	plasma	plasma	NN
cord-018142-xt71w4nr	215	5	exchange	exchange	NN
cord-018142-xt71w4nr	215	6	must	must	MD
cord-018142-xt71w4nr	215	7	be	be	VB
cord-018142-xt71w4nr	215	8	progressively	progressively	RB
cord-018142-xt71w4nr	215	9	decreased	decrease	VBN
cord-018142-xt71w4nr	215	10	.	.	.
cord-018142-xt71w4nr	216	1	Daily	Daily	NNP
cord-018142-xt71w4nr	216	2	plasma	plasma	NN
cord-018142-xt71w4nr	216	3	exchange	exchange	NN
cord-018142-xt71w4nr	216	4	must	must	MD
cord-018142-xt71w4nr	216	5	be	be	VB
cord-018142-xt71w4nr	216	6	reintroduced	reintroduce	VBN
cord-018142-xt71w4nr	216	7	at	at	IN
cord-018142-xt71w4nr	216	8	the	the	DT
cord-018142-xt71w4nr	216	9	slightest	slight	JJS
cord-018142-xt71w4nr	216	10	sign	sign	NN
cord-018142-xt71w4nr	216	11	of	of	IN
cord-018142-xt71w4nr	216	12	relapse	relapse	NN
cord-018142-xt71w4nr	216	13	.	.	.
cord-018142-xt71w4nr	217	1	In	in	IN
cord-018142-xt71w4nr	217	2	the	the	DT
cord-018142-xt71w4nr	217	3	future	future	NN
cord-018142-xt71w4nr	217	4	,	,	,
cord-018142-xt71w4nr	217	5	monitoring	monitoring	NN
cord-018142-xt71w4nr	217	6	of	of	IN
cord-018142-xt71w4nr	217	7	ADAMTS-13	adamts-13	ADD
cord-018142-xt71w4nr	217	8	protein	protein	NN
cord-018142-xt71w4nr	217	9	inhibitor	inhibitor	NN
cord-018142-xt71w4nr	217	10	levels	level	NNS
cord-018142-xt71w4nr	217	11	could	could	MD
cord-018142-xt71w4nr	217	12	guide	guide	VB
cord-018142-xt71w4nr	217	13	the	the	DT
cord-018142-xt71w4nr	217	14	frequency	frequency	NN
cord-018142-xt71w4nr	217	15	of	of	IN
cord-018142-xt71w4nr	217	16	plasma	plasma	NN
cord-018142-xt71w4nr	217	17	exchange	exchange	NN
cord-018142-xt71w4nr	217	18	.	.	.
cord-018142-xt71w4nr	218	1	During	during	IN
cord-018142-xt71w4nr	218	2	relapses	relapse	NNS
cord-018142-xt71w4nr	218	3	(	(	-LRB-
cord-018142-xt71w4nr	218	4	30	30	CD
cord-018142-xt71w4nr	218	5	%	%	NN
cord-018142-xt71w4nr	218	6	of	of	IN
cord-018142-xt71w4nr	218	7	cases	case	NNS
cord-018142-xt71w4nr	218	8	of	of	IN
cord-018142-xt71w4nr	218	9	TTP	TTP	NNP
cord-018142-xt71w4nr	218	10	)	)	-RRB-
cord-018142-xt71w4nr	218	11	,	,	,
cord-018142-xt71w4nr	218	12	the	the	DT
cord-018142-xt71w4nr	218	13	initial	initial	JJ
cord-018142-xt71w4nr	218	14	treatment	treatment	NN
cord-018142-xt71w4nr	218	15	in	in	IN
cord-018142-xt71w4nr	218	16	the	the	DT
cord-018142-xt71w4nr	218	17	acute	acute	JJ
cord-018142-xt71w4nr	218	18	phase	phase	NN
cord-018142-xt71w4nr	218	19	is	be	VBZ
cord-018142-xt71w4nr	218	20	the	the	DT
cord-018142-xt71w4nr	218	21	same	same	JJ
cord-018142-xt71w4nr	218	22	as	as	IN
cord-018142-xt71w4nr	218	23	for	for	IN
cord-018142-xt71w4nr	218	24	the	the	DT
cord-018142-xt71w4nr	218	25	first	first	JJ
cord-018142-xt71w4nr	218	26	episode	episode	NN
cord-018142-xt71w4nr	218	27	.	.	.
cord-018142-xt71w4nr	219	1	Repeated	repeat	VBN
cord-018142-xt71w4nr	219	2	relapses	relapse	NNS
cord-018142-xt71w4nr	219	3	may	may	MD
cord-018142-xt71w4nr	219	4	represent	represent	VB
cord-018142-xt71w4nr	219	5	an	an	DT
cord-018142-xt71w4nr	219	6	indication	indication	NN
cord-018142-xt71w4nr	219	7	for	for	IN
cord-018142-xt71w4nr	219	8	splenectomy	splenectomy	NN
cord-018142-xt71w4nr	219	9	,	,	,
cord-018142-xt71w4nr	219	10	during	during	IN
cord-018142-xt71w4nr	219	11	a	a	DT
cord-018142-xt71w4nr	219	12	period	period	NN
cord-018142-xt71w4nr	219	13	of	of	IN
cord-018142-xt71w4nr	219	14	remission	remission	NN
cord-018142-xt71w4nr	219	15	.	.	.
cord-018142-xt71w4nr	220	1	Refractory	refractory	JJ
cord-018142-xt71w4nr	220	2	TTP	TTP	NNP
cord-018142-xt71w4nr	220	3	,	,	,
cord-018142-xt71w4nr	220	4	defined	define	VBN
cord-018142-xt71w4nr	220	5	by	by	IN
cord-018142-xt71w4nr	220	6	no	no	DT
cord-018142-xt71w4nr	220	7	improvement	improvement	NN
cord-018142-xt71w4nr	220	8	of	of	IN
cord-018142-xt71w4nr	220	9	the	the	DT
cord-018142-xt71w4nr	220	10	platelet	platelet	NN
cord-018142-xt71w4nr	220	11	count	count	NN
cord-018142-xt71w4nr	220	12	on	on	IN
cord-018142-xt71w4nr	220	13	day	day	NN
cord-018142-xt71w4nr	220	14	5	5	CD
cord-018142-xt71w4nr	220	15	of	of	IN
cord-018142-xt71w4nr	220	16	treatment	treatment	NN
cord-018142-xt71w4nr	220	17	,	,	,
cord-018142-xt71w4nr	220	18	requires	require	VBZ
cord-018142-xt71w4nr	220	19	twice	twice	RB
cord-018142-xt71w4nr	220	20	-	-	HYPH
cord-018142-xt71w4nr	220	21	daily	daily	JJ
cord-018142-xt71w4nr	220	22	plasma	plasma	NN
cord-018142-xt71w4nr	220	23	exchange	exchange	NN
cord-018142-xt71w4nr	220	24	and	and	CC
cord-018142-xt71w4nr	220	25	adjuvant	adjuvant	JJ
cord-018142-xt71w4nr	220	26	therapies	therapy	NNS
cord-018142-xt71w4nr	220	27	(	(	-LRB-
cord-018142-xt71w4nr	220	28	vincristine	vincristine	NN
cord-018142-xt71w4nr	220	29	,	,	,
cord-018142-xt71w4nr	220	30	polyvalent	polyvalent	JJ
cord-018142-xt71w4nr	220	31	immunoglobulins	immunoglobulin	NNS
cord-018142-xt71w4nr	220	32	,	,	,
cord-018142-xt71w4nr	220	33	cyclophosphamide	cyclophosphamide	RB
cord-018142-xt71w4nr	220	34	:	:	:
cord-018142-xt71w4nr	220	35	see	see	VB
cord-018142-xt71w4nr	220	36	below	below	RB
cord-018142-xt71w4nr	220	37	)	)	-RRB-
cord-018142-xt71w4nr	220	38	[	[	-LRB-
cord-018142-xt71w4nr	220	39	38	38	CD
cord-018142-xt71w4nr	220	40	,	,	,
cord-018142-xt71w4nr	220	41	39	39	CD
cord-018142-xt71w4nr	220	42	]	]	-RRB-
cord-018142-xt71w4nr	220	43	.	.	.
cord-018142-xt71w4nr	221	1	High	high	JJ
cord-018142-xt71w4nr	221	2	-	-	HYPH
cord-018142-xt71w4nr	221	3	dose	dose	NN
cord-018142-xt71w4nr	221	4	corticosteroid	corticosteroid	NN
cord-018142-xt71w4nr	221	5	therapy	therapy	NN
cord-018142-xt71w4nr	221	6	is	be	VBZ
cord-018142-xt71w4nr	221	7	effective	effective	JJ
cord-018142-xt71w4nr	221	8	in	in	IN
cord-018142-xt71w4nr	221	9	56	56	CD
cord-018142-xt71w4nr	221	10	%	%	NN
cord-018142-xt71w4nr	221	11	of	of	IN
cord-018142-xt71w4nr	221	12	purely	purely	RB
cord-018142-xt71w4nr	221	13	hematological	hematological	JJ
cord-018142-xt71w4nr	221	14	forms	form	NNS
cord-018142-xt71w4nr	221	15	of	of	IN
cord-018142-xt71w4nr	221	16	TTP	TTP	NNP
cord-018142-xt71w4nr	221	17	[	[	-LRB-
cord-018142-xt71w4nr	221	18	31	31	CD
cord-018142-xt71w4nr	221	19	]	]	-RRB-
cord-018142-xt71w4nr	221	20	,	,	,
cord-018142-xt71w4nr	221	21	although	although	IN
cord-018142-xt71w4nr	221	22	its	-PRON-	PRP$
cord-018142-xt71w4nr	221	23	efficacy	efficacy	NN
cord-018142-xt71w4nr	221	24	has	have	VBZ
cord-018142-xt71w4nr	221	25	not	not	RB
cord-018142-xt71w4nr	221	26	been	be	VBN
cord-018142-xt71w4nr	221	27	clearly	clearly	RB
cord-018142-xt71w4nr	221	28	demonstrated	demonstrate	VBN
cord-018142-xt71w4nr	221	29	by	by	IN
cord-018142-xt71w4nr	221	30	randomized	randomized	JJ
cord-018142-xt71w4nr	221	31	trials	trial	NNS
cord-018142-xt71w4nr	221	32	.	.	.
cord-018142-xt71w4nr	222	1	In	in	IN
cord-018142-xt71w4nr	222	2	the	the	DT
cord-018142-xt71w4nr	222	3	absence	absence	NN
cord-018142-xt71w4nr	222	4	of	of	IN
cord-018142-xt71w4nr	222	5	a	a	DT
cord-018142-xt71w4nr	222	6	contraindication	contraindication	NN
cord-018142-xt71w4nr	222	7	(	(	-LRB-
cord-018142-xt71w4nr	222	8	active	active	JJ
cord-018142-xt71w4nr	222	9	infection	infection	NN
cord-018142-xt71w4nr	222	10	)	)	-RRB-
cord-018142-xt71w4nr	222	11	,	,	,
cord-018142-xt71w4nr	222	12	and	and	CC
cord-018142-xt71w4nr	222	13	despite	despite	IN
cord-018142-xt71w4nr	222	14	a	a	DT
cord-018142-xt71w4nr	222	15	low	low	JJ
cord-018142-xt71w4nr	222	16	level	level	NN
cord-018142-xt71w4nr	222	17	of	of	IN
cord-018142-xt71w4nr	222	18	evidence	evidence	NN
cord-018142-xt71w4nr	222	19	,	,	,
cord-018142-xt71w4nr	222	20	methylprednisolone	methylprednisolone	NNP
cord-018142-xt71w4nr	222	21	(	(	-LRB-
cord-018142-xt71w4nr	222	22	1	1	CD
cord-018142-xt71w4nr	222	23	mg	mg	NNP
cord-018142-xt71w4nr	222	24	/	/	SYM
cord-018142-xt71w4nr	222	25	kg	kg	NNP
cord-018142-xt71w4nr	222	26	/	/	SYM
cord-018142-xt71w4nr	222	27	day	day	NN
cord-018142-xt71w4nr	222	28	for	for	IN
cord-018142-xt71w4nr	222	29	3	3	CD
cord-018142-xt71w4nr	222	30	weeks	week	NNS
cord-018142-xt71w4nr	222	31	)	)	-RRB-
cord-018142-xt71w4nr	222	32	can	can	MD
cord-018142-xt71w4nr	222	33	be	be	VB
cord-018142-xt71w4nr	222	34	administered	administer	VBN
cord-018142-xt71w4nr	222	35	immediately	immediately	RB
cord-018142-xt71w4nr	222	36	following	follow	VBG
cord-018142-xt71w4nr	222	37	plasma	plasma	NN
cord-018142-xt71w4nr	222	38	exchange	exchange	NN
cord-018142-xt71w4nr	222	39	.	.	.
cord-018142-xt71w4nr	223	1	The	the	DT
cord-018142-xt71w4nr	223	2	therapeutic	therapeutic	JJ
cord-018142-xt71w4nr	223	3	value	value	NN
cord-018142-xt71w4nr	223	4	of	of	IN
cord-018142-xt71w4nr	223	5	platelet	platelet	NN
cord-018142-xt71w4nr	223	6	aggregation	aggregation	NN
cord-018142-xt71w4nr	223	7	inhibitors	inhibitor	NNS
cord-018142-xt71w4nr	223	8	,	,	,
cord-018142-xt71w4nr	223	9	vincristine	vincristine	NN
cord-018142-xt71w4nr	223	10	,	,	,
cord-018142-xt71w4nr	223	11	high	high	JJ
cord-018142-xt71w4nr	223	12	-	-	HYPH
cord-018142-xt71w4nr	223	13	dose	dose	NN
cord-018142-xt71w4nr	223	14	immunoglobulins	immunoglobulin	NNS
cord-018142-xt71w4nr	223	15	,	,	,
cord-018142-xt71w4nr	223	16	splenectomy	splenectomy	NN
cord-018142-xt71w4nr	223	17	,	,	,
cord-018142-xt71w4nr	223	18	immunosuppressives	immunosuppressive	NNS
cord-018142-xt71w4nr	223	19	,	,	,
cord-018142-xt71w4nr	223	20	unfractionated	unfractionated	JJ
cord-018142-xt71w4nr	223	21	heparin	heparin	NNP
cord-018142-xt71w4nr	223	22	,	,	,
cord-018142-xt71w4nr	223	23	fibri	fibri	NNP
cord-018142-xt71w4nr	223	24	-	-	HYPH
cord-018142-xt71w4nr	223	25	nolytics	nolytics	NNP
cord-018142-xt71w4nr	223	26	,	,	,
cord-018142-xt71w4nr	223	27	prostacyclin	prostacyclin	NNP
cord-018142-xt71w4nr	223	28	,	,	,
cord-018142-xt71w4nr	223	29	and	and	CC
cord-018142-xt71w4nr	223	30	vitamin	vitamin	NN
cord-018142-xt71w4nr	223	31	E	e	NN
cord-018142-xt71w4nr	223	32	in	in	IN
cord-018142-xt71w4nr	223	33	the	the	DT
cord-018142-xt71w4nr	223	34	intensive	intensive	JJ
cord-018142-xt71w4nr	223	35	care	care	NN
cord-018142-xt71w4nr	223	36	management	management	NN
cord-018142-xt71w4nr	223	37	of	of	IN
cord-018142-xt71w4nr	223	38	TMA	TMA	NNP
cord-018142-xt71w4nr	223	39	has	have	VBZ
cord-018142-xt71w4nr	223	40	not	not	RB
cord-018142-xt71w4nr	223	41	been	be	VBN
cord-018142-xt71w4nr	223	42	demonstrated	demonstrate	VBN
cord-018142-xt71w4nr	223	43	.	.	.
cord-018142-xt71w4nr	224	1	Staphylococcal	staphylococcal	JJ
cord-018142-xt71w4nr	224	2	protein	protein	NN
cord-018142-xt71w4nr	224	3	A	a	DT
cord-018142-xt71w4nr	224	4	columns	column	NNS
cord-018142-xt71w4nr	224	5	could	could	MD
cord-018142-xt71w4nr	224	6	be	be	VB
cord-018142-xt71w4nr	224	7	effective	effective	JJ
cord-018142-xt71w4nr	224	8	in	in	IN
cord-018142-xt71w4nr	224	9	TTP	TTP	NNP
cord-018142-xt71w4nr	224	10	,	,	,
cord-018142-xt71w4nr	224	11	especially	especially	RB
cord-018142-xt71w4nr	224	12	in	in	IN
cord-018142-xt71w4nr	224	13	a	a	DT
cord-018142-xt71w4nr	224	14	context	context	NN
cord-018142-xt71w4nr	224	15	of	of	IN
cord-018142-xt71w4nr	224	16	cancer	cancer	NN
cord-018142-xt71w4nr	224	17	,	,	,
cord-018142-xt71w4nr	224	18	but	but	CC
cord-018142-xt71w4nr	224	19	they	-PRON-	PRP
cord-018142-xt71w4nr	224	20	have	have	VBP
cord-018142-xt71w4nr	224	21	not	not	RB
cord-018142-xt71w4nr	224	22	been	be	VBN
cord-018142-xt71w4nr	224	23	evaluated	evaluate	VBN
cord-018142-xt71w4nr	224	24	in	in	IN
cord-018142-xt71w4nr	224	25	patients	patient	NNS
cord-018142-xt71w4nr	224	26	with	with	IN
cord-018142-xt71w4nr	224	27	an	an	DT
cord-018142-xt71w4nr	224	28	inhibitor	inhibitor	NN
cord-018142-xt71w4nr	224	29	[	[	-LRB-
cord-018142-xt71w4nr	224	30	40	40	CD
cord-018142-xt71w4nr	224	31	]	]	-RRB-
cord-018142-xt71w4nr	224	32	.	.	.
cord-018142-xt71w4nr	225	1	A	a	DT
cord-018142-xt71w4nr	225	2	possible	possible	JJ
cord-018142-xt71w4nr	225	3	treatment	treatment	NN
cord-018142-xt71w4nr	225	4	for	for	IN
cord-018142-xt71w4nr	225	5	the	the	DT
cord-018142-xt71w4nr	225	6	future	future	NN
cord-018142-xt71w4nr	225	7	would	would	MD
cord-018142-xt71w4nr	225	8	be	be	VB
cord-018142-xt71w4nr	225	9	purified	purify	VBN
cord-018142-xt71w4nr	225	10	or	or	CC
cord-018142-xt71w4nr	225	11	recombinant	recombinant	JJ
cord-018142-xt71w4nr	225	12	protease	protease	NN
cord-018142-xt71w4nr	225	13	infusion	infusion	NN
cord-018142-xt71w4nr	225	14	,	,	,
cord-018142-xt71w4nr	225	15	which	which	WDT
cord-018142-xt71w4nr	225	16	could	could	MD
cord-018142-xt71w4nr	225	17	replace	replace	VB
cord-018142-xt71w4nr	225	18	plasma	plasma	NN
cord-018142-xt71w4nr	225	19	therapy	therapy	NN
cord-018142-xt71w4nr	225	20	.	.	.
cord-018142-xt71w4nr	226	1	z	z	LS
cord-018142-xt71w4nr	226	2	Other	other	JJ
cord-018142-xt71w4nr	226	3	TMA	TMA	NNP
cord-018142-xt71w4nr	226	4	syndromes	syndrome	NNS
cord-018142-xt71w4nr	227	1	Pregnancy	pregnancy	NN
cord-018142-xt71w4nr	227	2	-	-	HYPH
cord-018142-xt71w4nr	227	3	associated	associate	VBN
cord-018142-xt71w4nr	227	4	TMA	TMA	NNP
cord-018142-xt71w4nr	227	5	Various	various	JJ
cord-018142-xt71w4nr	227	6	types	type	NNS
cord-018142-xt71w4nr	227	7	of	of	IN
cord-018142-xt71w4nr	227	8	TMA	TMA	NNP
cord-018142-xt71w4nr	227	9	can	can	MD
cord-018142-xt71w4nr	227	10	occur	occur	VB
cord-018142-xt71w4nr	227	11	during	during	IN
cord-018142-xt71w4nr	227	12	pregnancy	pregnancy	NN
cord-018142-xt71w4nr	227	13	and	and	CC
cord-018142-xt71w4nr	227	14	the	the	DT
cord-018142-xt71w4nr	227	15	post	post	JJ
cord-018142-xt71w4nr	227	16	-	-	JJ
cord-018142-xt71w4nr	227	17	partum	partum	JJ
cord-018142-xt71w4nr	227	18	period	period	NN
cord-018142-xt71w4nr	227	19	:	:	:
cord-018142-xt71w4nr	227	20	TTP	TTP	NNP
cord-018142-xt71w4nr	227	21	,	,	,
cord-018142-xt71w4nr	227	22	HUS	HUS	NNP
cord-018142-xt71w4nr	227	23	,	,	,
cord-018142-xt71w4nr	227	24	HELLP	HELLP	NNP
cord-018142-xt71w4nr	227	25	syndrome	syndrome	NN
cord-018142-xt71w4nr	227	26	.	.	.
cord-018142-xt71w4nr	228	1	Many	many	JJ
cord-018142-xt71w4nr	228	2	complications	complication	NNS
cord-018142-xt71w4nr	228	3	have	have	VBP
cord-018142-xt71w4nr	228	4	been	be	VBN
cord-018142-xt71w4nr	228	5	described	describe	VBN
cord-018142-xt71w4nr	228	6	including	include	VBG
cord-018142-xt71w4nr	228	7	acute	acute	JJ
cord-018142-xt71w4nr	228	8	necrotic	necrotic	JJ
cord-018142-xt71w4nr	228	9	pancreatitis	pancreatitis	NN
cord-018142-xt71w4nr	228	10	,	,	,
cord-018142-xt71w4nr	228	11	myocardial	myocardial	JJ
cord-018142-xt71w4nr	228	12	infarction	infarction	NN
cord-018142-xt71w4nr	228	13	,	,	,
cord-018142-xt71w4nr	228	14	gastrointestinal	gastrointestinal	JJ
cord-018142-xt71w4nr	228	15	ischemia	ischemia	NN
cord-018142-xt71w4nr	228	16	,	,	,
cord-018142-xt71w4nr	228	17	etc	etc	FW
cord-018142-xt71w4nr	228	18	.	.	.
cord-018142-xt71w4nr	229	1	The	the	DT
cord-018142-xt71w4nr	229	2	treatment	treatment	NN
cord-018142-xt71w4nr	229	3	of	of	IN
cord-018142-xt71w4nr	229	4	TTP	ttp	NN
cord-018142-xt71w4nr	229	5	during	during	IN
cord-018142-xt71w4nr	229	6	pregnancy	pregnancy	NN
cord-018142-xt71w4nr	229	7	is	be	VBZ
cord-018142-xt71w4nr	229	8	based	base	VBN
cord-018142-xt71w4nr	229	9	on	on	IN
cord-018142-xt71w4nr	229	10	plasma	plasma	NN
cord-018142-xt71w4nr	229	11	exchange	exchange	NN
cord-018142-xt71w4nr	229	12	.	.	.
cord-018142-xt71w4nr	230	1	Pregnancy	pregnancy	NN
cord-018142-xt71w4nr	230	2	does	do	VBZ
cord-018142-xt71w4nr	230	3	not	not	RB
cord-018142-xt71w4nr	230	4	modify	modify	VB
cord-018142-xt71w4nr	230	5	the	the	DT
cord-018142-xt71w4nr	230	6	response	response	NN
cord-018142-xt71w4nr	230	7	to	to	IN
cord-018142-xt71w4nr	230	8	treatment	treatment	NN
cord-018142-xt71w4nr	230	9	,	,	,
cord-018142-xt71w4nr	230	10	but	but	CC
cord-018142-xt71w4nr	230	11	the	the	DT
cord-018142-xt71w4nr	230	12	consequences	consequence	NNS
cord-018142-xt71w4nr	230	13	of	of	IN
cord-018142-xt71w4nr	230	14	plasma	plasma	NN
cord-018142-xt71w4nr	230	15	exchange	exchange	NN
cord-018142-xt71w4nr	230	16	on	on	IN
cord-018142-xt71w4nr	230	17	the	the	DT
cord-018142-xt71w4nr	230	18	fetus	fetus	NN
cord-018142-xt71w4nr	230	19	have	have	VBP
cord-018142-xt71w4nr	230	20	not	not	RB
cord-018142-xt71w4nr	230	21	been	be	VBN
cord-018142-xt71w4nr	230	22	evaluated	evaluate	VBN
cord-018142-xt71w4nr	230	23	.	.	.
cord-018142-xt71w4nr	231	1	There	there	EX
cord-018142-xt71w4nr	231	2	is	be	VBZ
cord-018142-xt71w4nr	231	3	a	a	DT
cord-018142-xt71w4nr	231	4	risk	risk	NN
cord-018142-xt71w4nr	231	5	of	of	IN
cord-018142-xt71w4nr	231	6	relapse	relapse	NN
cord-018142-xt71w4nr	231	7	during	during	IN
cord-018142-xt71w4nr	231	8	subsequent	subsequent	JJ
cord-018142-xt71w4nr	231	9	pregnancies	pregnancy	NNS
cord-018142-xt71w4nr	231	10	.	.	.
cord-018142-xt71w4nr	232	1	Ante	ante	JJ
cord-018142-xt71w4nr	232	2	-	-	HYPH
cord-018142-xt71w4nr	232	3	partum	partum	NN
cord-018142-xt71w4nr	232	4	HUS	HUS	NNP
cord-018142-xt71w4nr	232	5	requires	require	VBZ
cord-018142-xt71w4nr	232	6	termination	termination	NN
cord-018142-xt71w4nr	232	7	of	of	IN
cord-018142-xt71w4nr	232	8	pregnancy	pregnancy	NN
cord-018142-xt71w4nr	232	9	,	,	,
cord-018142-xt71w4nr	232	10	but	but	CC
cord-018142-xt71w4nr	232	11	has	have	VBZ
cord-018142-xt71w4nr	232	12	a	a	DT
cord-018142-xt71w4nr	232	13	fairly	fairly	RB
cord-018142-xt71w4nr	232	14	good	good	JJ
cord-018142-xt71w4nr	232	15	prognosis	prognosis	NN
cord-018142-xt71w4nr	232	16	.	.	.
cord-018142-xt71w4nr	233	1	Post	post	JJ
cord-018142-xt71w4nr	233	2	-	-	JJ
cord-018142-xt71w4nr	233	3	partum	partum	JJ
cord-018142-xt71w4nr	233	4	HUS	hus	NN
cord-018142-xt71w4nr	233	5	can	can	MD
cord-018142-xt71w4nr	233	6	occur	occur	VB
cord-018142-xt71w4nr	233	7	up	up	IN
cord-018142-xt71w4nr	233	8	to	to	TO
cord-018142-xt71w4nr	233	9	3	3	CD
cord-018142-xt71w4nr	233	10	months	month	NNS
cord-018142-xt71w4nr	233	11	after	after	IN
cord-018142-xt71w4nr	233	12	delivery	delivery	NN
cord-018142-xt71w4nr	233	13	and	and	CC
cord-018142-xt71w4nr	233	14	has	have	VBZ
cord-018142-xt71w4nr	233	15	a	a	DT
cord-018142-xt71w4nr	233	16	poorer	poor	JJR
cord-018142-xt71w4nr	233	17	prognosis	prognosis	NN
cord-018142-xt71w4nr	233	18	.	.	.
cord-018142-xt71w4nr	234	1	Death	death	NN
cord-018142-xt71w4nr	234	2	may	may	MD
cord-018142-xt71w4nr	234	3	be	be	VB
cord-018142-xt71w4nr	234	4	due	due	JJ
cord-018142-xt71w4nr	234	5	to	to	IN
cord-018142-xt71w4nr	234	6	cerebral	cerebral	JJ
cord-018142-xt71w4nr	234	7	ischemic	ischemic	JJ
cord-018142-xt71w4nr	234	8	or	or	CC
cord-018142-xt71w4nr	234	9	hemorrhagic	hemorrhagic	JJ
cord-018142-xt71w4nr	234	10	lesions	lesion	NNS
cord-018142-xt71w4nr	234	11	or	or	CC
cord-018142-xt71w4nr	234	12	cardiac	cardiac	JJ
cord-018142-xt71w4nr	234	13	sudden	sudden	JJ
cord-018142-xt71w4nr	234	14	death	death	NN
cord-018142-xt71w4nr	234	15	.	.	.
cord-018142-xt71w4nr	235	1	Some	some	DT
cord-018142-xt71w4nr	235	2	cases	case	NNS
cord-018142-xt71w4nr	235	3	of	of	IN
cord-018142-xt71w4nr	235	4	post	post	JJ
cord-018142-xt71w4nr	235	5	-	-	JJ
cord-018142-xt71w4nr	235	6	partum	partum	JJ
cord-018142-xt71w4nr	235	7	HUS	hus	NN
cord-018142-xt71w4nr	235	8	are	be	VBP
cord-018142-xt71w4nr	235	9	related	relate	VBN
cord-018142-xt71w4nr	235	10	to	to	IN
cord-018142-xt71w4nr	235	11	factor	factor	NN
cord-018142-xt71w4nr	235	12	H	h	NN
cord-018142-xt71w4nr	235	13	deficiency	deficiency	NN
cord-018142-xt71w4nr	235	14	(	(	-LRB-
cord-018142-xt71w4nr	235	15	heterozygous	heterozygous	JJ
cord-018142-xt71w4nr	235	16	mutation	mutation	NN
cord-018142-xt71w4nr	235	17	)	)	-RRB-
cord-018142-xt71w4nr	235	18	.	.	.
cord-018142-xt71w4nr	236	1	The	the	DT
cord-018142-xt71w4nr	236	2	HELLP	HELLP	NNP
cord-018142-xt71w4nr	236	3	syndrome	syndrome	NN
cord-018142-xt71w4nr	236	4	(	(	-LRB-
cord-018142-xt71w4nr	236	5	hepatic	hepatic	JJ
cord-018142-xt71w4nr	236	6	form	form	NN
cord-018142-xt71w4nr	236	7	of	of	IN
cord-018142-xt71w4nr	236	8	TMA	TMA	NNP
cord-018142-xt71w4nr	236	9	)	)	-RRB-
cord-018142-xt71w4nr	236	10	is	be	VBZ
cord-018142-xt71w4nr	236	11	a	a	DT
cord-018142-xt71w4nr	236	12	TMA	TMA	NNP
cord-018142-xt71w4nr	236	13	disorder	disorder	NN
cord-018142-xt71w4nr	236	14	specific	specific	JJ
cord-018142-xt71w4nr	236	15	to	to	IN
cord-018142-xt71w4nr	236	16	pregnancy	pregnancy	NN
cord-018142-xt71w4nr	236	17	.	.	.
cord-018142-xt71w4nr	237	1	It	-PRON-	PRP
cord-018142-xt71w4nr	237	2	differs	differ	VBZ
cord-018142-xt71w4nr	237	3	from	from	IN
cord-018142-xt71w4nr	237	4	HUS	HUS	NNP
cord-018142-xt71w4nr	237	5	and	and	CC
cord-018142-xt71w4nr	237	6	TTP	TTP	NNP
cord-018142-xt71w4nr	237	7	by	by	IN
cord-018142-xt71w4nr	237	8	the	the	DT
cord-018142-xt71w4nr	237	9	presence	presence	NN
cord-018142-xt71w4nr	237	10	of	of	IN
cord-018142-xt71w4nr	237	11	DIC	DIC	NNP
cord-018142-xt71w4nr	237	12	and	and	CC
cord-018142-xt71w4nr	237	13	liver	liver	NN
cord-018142-xt71w4nr	237	14	impairment	impairment	NN
cord-018142-xt71w4nr	237	15	.	.	.
cord-018142-xt71w4nr	238	1	Treatment	treatment	NN
cord-018142-xt71w4nr	238	2	consists	consist	VBZ
cord-018142-xt71w4nr	238	3	of	of	IN
cord-018142-xt71w4nr	238	4	fetal	fetal	JJ
cord-018142-xt71w4nr	238	5	extraction	extraction	NN
cord-018142-xt71w4nr	238	6	.	.	.
cord-018142-xt71w4nr	239	1	Plasma	plasma	NN
cord-018142-xt71w4nr	239	2	therapy	therapy	NN
cord-018142-xt71w4nr	239	3	has	have	VBZ
cord-018142-xt71w4nr	239	4	been	be	VBN
cord-018142-xt71w4nr	239	5	proposed	propose	VBN
cord-018142-xt71w4nr	239	6	(	(	-LRB-
cord-018142-xt71w4nr	239	7	3	3	CD
cord-018142-xt71w4nr	239	8	to	to	TO
cord-018142-xt71w4nr	239	9	5	5	CD
cord-018142-xt71w4nr	239	10	post	post	JJ
cord-018142-xt71w4nr	239	11	-	-	JJ
cord-018142-xt71w4nr	239	12	partum	partum	JJ
cord-018142-xt71w4nr	239	13	sessions	session	NNS
cord-018142-xt71w4nr	239	14	appear	appear	VBP
cord-018142-xt71w4nr	239	15	to	to	TO
cord-018142-xt71w4nr	239	16	be	be	VB
cord-018142-xt71w4nr	239	17	effective	effective	JJ
cord-018142-xt71w4nr	239	18	)	)	-RRB-
cord-018142-xt71w4nr	239	19	.	.	.
cord-018142-xt71w4nr	240	1	There	there	EX
cord-018142-xt71w4nr	240	2	is	be	VBZ
cord-018142-xt71w4nr	240	3	a	a	DT
cord-018142-xt71w4nr	240	4	risk	risk	NN
cord-018142-xt71w4nr	240	5	of	of	IN
cord-018142-xt71w4nr	240	6	recurrence	recurrence	NN
cord-018142-xt71w4nr	240	7	during	during	IN
cord-018142-xt71w4nr	240	8	subsequent	subsequent	JJ
cord-018142-xt71w4nr	240	9	pregnancies	pregnancy	NNS
cord-018142-xt71w4nr	240	10	.	.	.
cord-018142-xt71w4nr	241	1	These	these	DT
cord-018142-xt71w4nr	241	2	patients	patient	NNS
cord-018142-xt71w4nr	241	3	should	should	MD
cord-018142-xt71w4nr	241	4	preferably	preferably	RB
cord-018142-xt71w4nr	241	5	be	be	VB
cord-018142-xt71w4nr	241	6	treated	treat	VBN
cord-018142-xt71w4nr	241	7	in	in	IN
cord-018142-xt71w4nr	241	8	a	a	DT
cord-018142-xt71w4nr	241	9	specialized	specialized	JJ
cord-018142-xt71w4nr	241	10	center	center	NN
cord-018142-xt71w4nr	241	11	.	.	.
cord-018142-xt71w4nr	242	1	In	in	IN
cord-018142-xt71w4nr	242	2	this	this	DT
cord-018142-xt71w4nr	242	3	context	context	NN
cord-018142-xt71w4nr	242	4	,	,	,
cord-018142-xt71w4nr	242	5	TMA	TMA	NNP
cord-018142-xt71w4nr	242	6	is	be	VBZ
cord-018142-xt71w4nr	242	7	triggered	trigger	VBN
cord-018142-xt71w4nr	242	8	by	by	IN
cord-018142-xt71w4nr	242	9	various	various	JJ
cord-018142-xt71w4nr	242	10	predisposing	predisposing	JJ
cord-018142-xt71w4nr	242	11	factors	factor	NNS
cord-018142-xt71w4nr	242	12	including	include	VBG
cord-018142-xt71w4nr	242	13	total	total	JJ
cord-018142-xt71w4nr	242	14	body	body	NN
cord-018142-xt71w4nr	242	15	irradiation	irradiation	NN
cord-018142-xt71w4nr	242	16	,	,	,
cord-018142-xt71w4nr	242	17	infections	infection	NNS
cord-018142-xt71w4nr	242	18	(	(	-LRB-
cord-018142-xt71w4nr	242	19	immunodepressed	immunodepressed	JJ
cord-018142-xt71w4nr	242	20	patients	patient	NNS
cord-018142-xt71w4nr	242	21	)	)	-RRB-
cord-018142-xt71w4nr	242	22	,	,	,
cord-018142-xt71w4nr	242	23	drugs	drug	NNS
cord-018142-xt71w4nr	242	24	(	(	-LRB-
cord-018142-xt71w4nr	242	25	tacrolimus	tacrolimus	RB
cord-018142-xt71w4nr	242	26	,	,	,
cord-018142-xt71w4nr	242	27	cyclosporine	cyclosporine	NNP
cord-018142-xt71w4nr	242	28	A	A	NNP
cord-018142-xt71w4nr	242	29	)	)	-RRB-
cord-018142-xt71w4nr	242	30	,	,	,
cord-018142-xt71w4nr	242	31	and	and	CC
cord-018142-xt71w4nr	242	32	acute	acute	JJ
cord-018142-xt71w4nr	242	33	graft	graft	NN
cord-018142-xt71w4nr	242	34	versus	versus	IN
cord-018142-xt71w4nr	242	35	host	host	NN
cord-018142-xt71w4nr	242	36	disease	disease	NN
cord-018142-xt71w4nr	242	37	.	.	.
cord-018142-xt71w4nr	243	1	These	these	DT
cord-018142-xt71w4nr	243	2	predisposing	predisposing	JJ
cord-018142-xt71w4nr	243	3	factors	factor	NNS
cord-018142-xt71w4nr	243	4	induce	induce	VBP
cord-018142-xt71w4nr	243	5	disseminated	disseminate	VBN
cord-018142-xt71w4nr	243	6	endothelial	endothelial	JJ
cord-018142-xt71w4nr	243	7	damage	damage	NN
cord-018142-xt71w4nr	243	8	.	.	.
cord-018142-xt71w4nr	244	1	The	the	DT
cord-018142-xt71w4nr	244	2	ADAMTS-13	adamts-13	DT
cord-018142-xt71w4nr	244	3	protein	protein	NN
cord-018142-xt71w4nr	244	4	level	level	NN
cord-018142-xt71w4nr	244	5	is	be	VBZ
cord-018142-xt71w4nr	244	6	normal	normal	JJ
cord-018142-xt71w4nr	244	7	and	and	CC
cord-018142-xt71w4nr	244	8	the	the	DT
cord-018142-xt71w4nr	244	9	response	response	NN
cord-018142-xt71w4nr	244	10	to	to	IN
cord-018142-xt71w4nr	244	11	treatment	treatment	NN
cord-018142-xt71w4nr	244	12	is	be	VBZ
cord-018142-xt71w4nr	244	13	disappointing	disappointing	JJ
cord-018142-xt71w4nr	244	14	.	.	.
cord-018142-xt71w4nr	245	1	Plasma	plasma	NN
cord-018142-xt71w4nr	245	2	exchange	exchange	NN
cord-018142-xt71w4nr	245	3	improves	improve	VBZ
cord-018142-xt71w4nr	245	4	the	the	DT
cord-018142-xt71w4nr	245	5	prognosis	prognosis	NN
cord-018142-xt71w4nr	245	6	,	,	,
cord-018142-xt71w4nr	245	7	which	which	WDT
cord-018142-xt71w4nr	245	8	nevertheless	nevertheless	RB
cord-018142-xt71w4nr	245	9	remains	remain	VBZ
cord-018142-xt71w4nr	245	10	poor	poor	JJ
cord-018142-xt71w4nr	245	11	.	.	.
cord-018142-xt71w4nr	246	1	Management	management	NN
cord-018142-xt71w4nr	246	2	of	of	IN
cord-018142-xt71w4nr	246	3	predisposing	predisposing	JJ
cord-018142-xt71w4nr	246	4	factors	factor	NNS
cord-018142-xt71w4nr	246	5	is	be	VBZ
cord-018142-xt71w4nr	246	6	an	an	DT
cord-018142-xt71w4nr	246	7	essential	essential	JJ
cord-018142-xt71w4nr	246	8	aspect	aspect	NN
cord-018142-xt71w4nr	246	9	of	of	IN
cord-018142-xt71w4nr	246	10	treatment	treatment	NN
cord-018142-xt71w4nr	246	11	.	.	.
cord-018142-xt71w4nr	247	1	TMA	TMA	NNP
cord-018142-xt71w4nr	247	2	is	be	VBZ
cord-018142-xt71w4nr	247	3	essentially	essentially	RB
cord-018142-xt71w4nr	247	4	associated	associate	VBN
cord-018142-xt71w4nr	247	5	with	with	IN
cord-018142-xt71w4nr	247	6	secretory	secretory	JJ
cord-018142-xt71w4nr	247	7	adenocarcinomas	adenocarcinomas	NNP
cord-018142-xt71w4nr	247	8	,	,	,
cord-018142-xt71w4nr	247	9	such	such	JJ
cord-018142-xt71w4nr	247	10	as	as	IN
cord-018142-xt71w4nr	247	11	breast	breast	NN
cord-018142-xt71w4nr	247	12	or	or	CC
cord-018142-xt71w4nr	247	13	stomach	stomach	NN
cord-018142-xt71w4nr	247	14	cancers	cancer	NNS
cord-018142-xt71w4nr	247	15	,	,	,
cord-018142-xt71w4nr	247	16	or	or	CC
cord-018142-xt71w4nr	247	17	more	more	RBR
cord-018142-xt71w4nr	247	18	rarely	rarely	RB
cord-018142-xt71w4nr	247	19	lung	lung	NN
cord-018142-xt71w4nr	247	20	,	,	,
cord-018142-xt71w4nr	247	21	colon	colon	NN
cord-018142-xt71w4nr	247	22	or	or	CC
cord-018142-xt71w4nr	247	23	prostate	prostate	NN
cord-018142-xt71w4nr	247	24	cancers	cancer	NNS
cord-018142-xt71w4nr	247	25	.	.	.
cord-018142-xt71w4nr	248	1	Stomach	stomach	NN
cord-018142-xt71w4nr	248	2	cancers	cancer	NNS
cord-018142-xt71w4nr	248	3	represent	represent	VBP
cord-018142-xt71w4nr	248	4	more	more	JJR
cord-018142-xt71w4nr	248	5	than	than	IN
cord-018142-xt71w4nr	248	6	50	50	CD
cord-018142-xt71w4nr	248	7	%	%	NN
cord-018142-xt71w4nr	248	8	of	of	IN
cord-018142-xt71w4nr	248	9	all	all	DT
cord-018142-xt71w4nr	248	10	reported	report	VBN
cord-018142-xt71w4nr	248	11	cases	case	NNS
cord-018142-xt71w4nr	248	12	of	of	IN
cord-018142-xt71w4nr	248	13	cancer	cancer	NN
cord-018142-xt71w4nr	248	14	-	-	HYPH
cord-018142-xt71w4nr	248	15	associated	associate	VBN
cord-018142-xt71w4nr	248	16	TMA	TMA	NNP
cord-018142-xt71w4nr	248	17	.	.	.
cord-018142-xt71w4nr	249	1	In	in	IN
cord-018142-xt71w4nr	249	2	most	most	JJS
cord-018142-xt71w4nr	249	3	cases	case	NNS
cord-018142-xt71w4nr	249	4	,	,	,
cord-018142-xt71w4nr	249	5	the	the	DT
cord-018142-xt71w4nr	249	6	cancer	cancer	NN
cord-018142-xt71w4nr	249	7	has	have	VBZ
cord-018142-xt71w4nr	249	8	already	already	RB
cord-018142-xt71w4nr	249	9	been	be	VBN
cord-018142-xt71w4nr	249	10	diagnosed	diagnose	VBN
cord-018142-xt71w4nr	249	11	and	and	CC
cord-018142-xt71w4nr	249	12	treated	treat	VBN
cord-018142-xt71w4nr	249	13	,	,	,
cord-018142-xt71w4nr	249	14	but	but	CC
cord-018142-xt71w4nr	249	15	TTP	TTP	NNP
cord-018142-xt71w4nr	249	16	can	can	MD
cord-018142-xt71w4nr	249	17	also	also	RB
cord-018142-xt71w4nr	249	18	be	be	VB
cord-018142-xt71w4nr	249	19	the	the	DT
cord-018142-xt71w4nr	249	20	first	first	JJ
cord-018142-xt71w4nr	249	21	sign	sign	NN
cord-018142-xt71w4nr	249	22	of	of	IN
cord-018142-xt71w4nr	249	23	cancer	cancer	NN
cord-018142-xt71w4nr	249	24	.	.	.
cord-018142-xt71w4nr	250	1	The	the	DT
cord-018142-xt71w4nr	250	2	pathophysiology	pathophysiology	NN
cord-018142-xt71w4nr	250	3	of	of	IN
cord-018142-xt71w4nr	250	4	cancer	cancer	NN
cord-018142-xt71w4nr	250	5	-	-	HYPH
cord-018142-xt71w4nr	250	6	associated	associate	VBN
cord-018142-xt71w4nr	250	7	TMA	TMA	NNP
cord-018142-xt71w4nr	250	8	has	have	VBZ
cord-018142-xt71w4nr	250	9	been	be	VBN
cord-018142-xt71w4nr	250	10	poorly	poorly	RB
cord-018142-xt71w4nr	250	11	elucidated	elucidate	VBN
cord-018142-xt71w4nr	250	12	and	and	CC
cord-018142-xt71w4nr	250	13	is	be	VBZ
cord-018142-xt71w4nr	250	14	associated	associate	VBN
cord-018142-xt71w4nr	250	15	with	with	IN
cord-018142-xt71w4nr	250	16	variable	variable	JJ
cord-018142-xt71w4nr	250	17	ADAMTS-13	adamts-13	ADD
cord-018142-xt71w4nr	250	18	protein	protein	NN
cord-018142-xt71w4nr	250	19	levels	level	NNS
cord-018142-xt71w4nr	250	20	.	.	.
cord-018142-xt71w4nr	251	1	The	the	DT
cord-018142-xt71w4nr	251	2	prognosis	prognosis	NN
cord-018142-xt71w4nr	251	3	is	be	VBZ
cord-018142-xt71w4nr	251	4	also	also	RB
cord-018142-xt71w4nr	251	5	variable	variable	JJ
cord-018142-xt71w4nr	251	6	and	and	CC
cord-018142-xt71w4nr	251	7	depends	depend	VBZ
cord-018142-xt71w4nr	251	8	on	on	IN
cord-018142-xt71w4nr	251	9	the	the	DT
cord-018142-xt71w4nr	251	10	underlying	underlie	VBG
cord-018142-xt71w4nr	251	11	cancer	cancer	NN
cord-018142-xt71w4nr	251	12	.	.	.
cord-018142-xt71w4nr	252	1	Drug	drug	NN
cord-018142-xt71w4nr	252	2	-	-	:
cord-018142-xt71w4nr	252	3	or	or	CC
cord-018142-xt71w4nr	252	4	Toxin	toxin	NN
cord-018142-xt71w4nr	252	5	-	-	HYPH
cord-018142-xt71w4nr	252	6	associated	associate	VBN
cord-018142-xt71w4nr	252	7	TMA	TMA	NNP
cord-018142-xt71w4nr	253	1	Many	many	JJ
cord-018142-xt71w4nr	253	2	drugs	drug	NNS
cord-018142-xt71w4nr	253	3	have	have	VBP
cord-018142-xt71w4nr	253	4	been	be	VBN
cord-018142-xt71w4nr	253	5	incriminated	incriminate	VBN
cord-018142-xt71w4nr	253	6	or	or	CC
cord-018142-xt71w4nr	253	7	suspected	suspect	VBN
cord-018142-xt71w4nr	253	8	including	include	VBG
cord-018142-xt71w4nr	253	9	ticlopidine	ticlopidine	NN
cord-018142-xt71w4nr	253	10	,	,	,
cord-018142-xt71w4nr	253	11	clopidogrel	clopidogrel	NN
cord-018142-xt71w4nr	253	12	,	,	,
cord-018142-xt71w4nr	253	13	cyclosporine	cyclosporine	NN
cord-018142-xt71w4nr	253	14	A	A	NNP
cord-018142-xt71w4nr	253	15	,	,	,
cord-018142-xt71w4nr	253	16	tacrolimus	tacrolimus	NN
cord-018142-xt71w4nr	253	17	,	,	,
cord-018142-xt71w4nr	253	18	interferon	interferon	NN
cord-018142-xt71w4nr	253	19	alpha	alpha	NN
cord-018142-xt71w4nr	253	20	,	,	,
cord-018142-xt71w4nr	253	21	oral	oral	JJ
cord-018142-xt71w4nr	253	22	contraceptives	contraceptive	NNS
cord-018142-xt71w4nr	253	23	,	,	,
cord-018142-xt71w4nr	253	24	quinine	quinine	NN
cord-018142-xt71w4nr	253	25	,	,	,
cord-018142-xt71w4nr	253	26	cisplatin	cisplatin	NN
cord-018142-xt71w4nr	253	27	,	,	,
cord-018142-xt71w4nr	253	28	mitomycin	mitomycin	NNS
cord-018142-xt71w4nr	253	29	C	c	NN
cord-018142-xt71w4nr	253	30	,	,	,
cord-018142-xt71w4nr	253	31	bleomycin	bleomycin	NN
cord-018142-xt71w4nr	253	32	,	,	,
cord-018142-xt71w4nr	253	33	arsenic	arsenic	NN
cord-018142-xt71w4nr	253	34	,	,	,
cord-018142-xt71w4nr	253	35	penicillamine	penicillamine	NNP
cord-018142-xt71w4nr	253	36	D.	D.	NNP
cord-018142-xt71w4nr	253	37	Ticlopidine	Ticlopidine	NNP
cord-018142-xt71w4nr	253	38	and	and	CC
cord-018142-xt71w4nr	253	39	clopidogrel	clopidogrel	NNS
cord-018142-xt71w4nr	253	40	are	be	VBP
cord-018142-xt71w4nr	253	41	associated	associate	VBN
cord-018142-xt71w4nr	253	42	with	with	IN
cord-018142-xt71w4nr	253	43	severe	severe	JJ
cord-018142-xt71w4nr	253	44	ADAMTS-13	adamts-13	NN
cord-018142-xt71w4nr	253	45	protein	protein	NN
cord-018142-xt71w4nr	253	46	deficiency	deficiency	NN
cord-018142-xt71w4nr	253	47	with	with	IN
cord-018142-xt71w4nr	253	48	the	the	DT
cord-018142-xt71w4nr	253	49	presence	presence	NN
cord-018142-xt71w4nr	253	50	of	of	IN
cord-018142-xt71w4nr	253	51	plasma	plasma	NN
cord-018142-xt71w4nr	253	52	inhibitors	inhibitor	NNS
cord-018142-xt71w4nr	253	53	.	.	.
cord-018142-xt71w4nr	254	1	Plasma	plasma	NN
cord-018142-xt71w4nr	254	2	exchange	exchange	NN
cord-018142-xt71w4nr	254	3	therapy	therapy	NN
cord-018142-xt71w4nr	254	4	achieves	achieve	VBZ
cord-018142-xt71w4nr	254	5	complete	complete	JJ
cord-018142-xt71w4nr	254	6	remission	remission	NN
cord-018142-xt71w4nr	254	7	in	in	IN
cord-018142-xt71w4nr	254	8	the	the	DT
cord-018142-xt71w4nr	254	9	majority	majority	NN
cord-018142-xt71w4nr	254	10	of	of	IN
cord-018142-xt71w4nr	254	11	these	these	DT
cord-018142-xt71w4nr	254	12	patients	patient	NNS
cord-018142-xt71w4nr	254	13	[	[	-LRB-
cord-018142-xt71w4nr	254	14	41	41	CD
cord-018142-xt71w4nr	254	15	,	,	,
cord-018142-xt71w4nr	254	16	42	42	CD
cord-018142-xt71w4nr	254	17	]	]	-RRB-
cord-018142-xt71w4nr	254	18	.	.	.
cord-018142-xt71w4nr	255	1	TMA	TMA	NNP
cord-018142-xt71w4nr	255	2	associated	associate	VBN
cord-018142-xt71w4nr	255	3	with	with	IN
cord-018142-xt71w4nr	255	4	mitomycin	mitomycin	NNS
cord-018142-xt71w4nr	255	5	C	C	NNP
cord-018142-xt71w4nr	255	6	is	be	VBZ
cord-018142-xt71w4nr	255	7	dose	dose	NN
cord-018142-xt71w4nr	255	8	-	-	HYPH
cord-018142-xt71w4nr	255	9	dependent	dependent	JJ
cord-018142-xt71w4nr	255	10	and	and	CC
cord-018142-xt71w4nr	255	11	is	be	VBZ
cord-018142-xt71w4nr	255	12	observed	observe	VBN
cord-018142-xt71w4nr	255	13	after	after	IN
cord-018142-xt71w4nr	255	14	a	a	DT
cord-018142-xt71w4nr	255	15	total	total	JJ
cord-018142-xt71w4nr	255	16	dose	dose	NN
cord-018142-xt71w4nr	255	17	of	of	IN
cord-018142-xt71w4nr	255	18	more	more	JJR
cord-018142-xt71w4nr	255	19	than	than	IN
cord-018142-xt71w4nr	255	20	60	60	CD
cord-018142-xt71w4nr	255	21	mg	mg	NN
cord-018142-xt71w4nr	255	22	(	(	-LRB-
cord-018142-xt71w4nr	255	23	2	2	CD
cord-018142-xt71w4nr	255	24	to	to	TO
cord-018142-xt71w4nr	255	25	10	10	CD
cord-018142-xt71w4nr	255	26	%	%	NN
cord-018142-xt71w4nr	255	27	of	of	IN
cord-018142-xt71w4nr	255	28	treated	treat	VBN
cord-018142-xt71w4nr	255	29	patients	patient	NNS
cord-018142-xt71w4nr	255	30	)	)	-RRB-
cord-018142-xt71w4nr	255	31	.	.	.
cord-018142-xt71w4nr	256	1	The	the	DT
cord-018142-xt71w4nr	256	2	TMA	TMA	NNP
cord-018142-xt71w4nr	256	3	disorders	disorder	NNS
cord-018142-xt71w4nr	256	4	often	often	RB
cord-018142-xt71w4nr	256	5	appear	appear	VBP
cord-018142-xt71w4nr	256	6	several	several	JJ
cord-018142-xt71w4nr	256	7	months	month	NNS
cord-018142-xt71w4nr	256	8	after	after	IN
cord-018142-xt71w4nr	256	9	stopping	stop	VBG
cord-018142-xt71w4nr	256	10	mitomycin	mitomycin	NNS
cord-018142-xt71w4nr	256	11	C	C	NNP
cord-018142-xt71w4nr	256	12	and	and	CC
cord-018142-xt71w4nr	256	13	are	be	VBP
cord-018142-xt71w4nr	256	14	characterized	characterize	VBN
cord-018142-xt71w4nr	256	15	by	by	IN
cord-018142-xt71w4nr	256	16	hypertension	hypertension	NN
cord-018142-xt71w4nr	256	17	and	and	CC
cord-018142-xt71w4nr	256	18	pulmonary	pulmonary	JJ
cord-018142-xt71w4nr	256	19	edema	edema	NN
cord-018142-xt71w4nr	256	20	[	[	-LRB-
cord-018142-xt71w4nr	256	21	43	43	CD
cord-018142-xt71w4nr	256	22	]	]	-RRB-
cord-018142-xt71w4nr	256	23	.	.	.
cord-018142-xt71w4nr	257	1	Neurological	neurological	JJ
cord-018142-xt71w4nr	257	2	disorders	disorder	NNS
cord-018142-xt71w4nr	257	3	and	and	CC
cord-018142-xt71w4nr	257	4	hyperthermia	hyperthermia	NN
cord-018142-xt71w4nr	257	5	are	be	VBP
cord-018142-xt71w4nr	257	6	rarely	rarely	RB
cord-018142-xt71w4nr	257	7	present	present	JJ
cord-018142-xt71w4nr	257	8	.	.	.
cord-018142-xt71w4nr	258	1	The	the	DT
cord-018142-xt71w4nr	258	2	prognosis	prognosis	NN
cord-018142-xt71w4nr	258	3	is	be	VBZ
cord-018142-xt71w4nr	258	4	very	very	RB
cord-018142-xt71w4nr	258	5	serious	serious	JJ
cord-018142-xt71w4nr	258	6	despite	despite	IN
cord-018142-xt71w4nr	258	7	discontinuation	discontinuation	NN
cord-018142-xt71w4nr	258	8	of	of	IN
cord-018142-xt71w4nr	258	9	mitomycin	mitomycin	NNS
cord-018142-xt71w4nr	258	10	and	and	CC
cord-018142-xt71w4nr	258	11	treatment	treatment	NN
cord-018142-xt71w4nr	258	12	by	by	IN
cord-018142-xt71w4nr	258	13	plasma	plasma	NN
cord-018142-xt71w4nr	258	14	exchange	exchange	NN
cord-018142-xt71w4nr	259	1	(	(	-LRB-
cord-018142-xt71w4nr	259	2	mortality	mortality	NN
cord-018142-xt71w4nr	259	3	of	of	IN
cord-018142-xt71w4nr	259	4	60	60	CD
cord-018142-xt71w4nr	259	5	to	to	TO
cord-018142-xt71w4nr	259	6	70	70	CD
cord-018142-xt71w4nr	259	7	%	%	NN
cord-018142-xt71w4nr	259	8	)	)	-RRB-
cord-018142-xt71w4nr	259	9	.	.	.
cord-018142-xt71w4nr	260	1	HIV	HIV	NNP
cord-018142-xt71w4nr	260	2	-	-	HYPH
cord-018142-xt71w4nr	260	3	associated	associate	VBN
cord-018142-xt71w4nr	260	4	TMA	TMA	NNP
cord-018142-xt71w4nr	260	5	[	[	-LRB-
cord-018142-xt71w4nr	260	6	12	12	CD
cord-018142-xt71w4nr	260	7	]	]	-RRB-
cord-018142-xt71w4nr	261	1	These	these	DT
cord-018142-xt71w4nr	261	2	forms	form	NNS
cord-018142-xt71w4nr	261	3	of	of	IN
cord-018142-xt71w4nr	261	4	TMA	TMA	NNP
cord-018142-xt71w4nr	261	5	generally	generally	RB
cord-018142-xt71w4nr	261	6	occur	occur	VBP
cord-018142-xt71w4nr	261	7	at	at	IN
cord-018142-xt71w4nr	261	8	an	an	DT
cord-018142-xt71w4nr	261	9	advanced	advanced	JJ
cord-018142-xt71w4nr	261	10	stage	stage	NN
cord-018142-xt71w4nr	261	11	of	of	IN
cord-018142-xt71w4nr	261	12	HIV	HIV	NNP
cord-018142-xt71w4nr	261	13	infection	infection	NN
cord-018142-xt71w4nr	261	14	and	and	CC
cord-018142-xt71w4nr	261	15	,	,	,
cord-018142-xt71w4nr	261	16	therefore	therefore	RB
cord-018142-xt71w4nr	261	17	,	,	,
cord-018142-xt71w4nr	261	18	have	have	VBP
cord-018142-xt71w4nr	261	19	a	a	DT
cord-018142-xt71w4nr	261	20	very	very	RB
cord-018142-xt71w4nr	261	21	poor	poor	JJ
cord-018142-xt71w4nr	261	22	prognosis	prognosis	NN
cord-018142-xt71w4nr	261	23	.	.	.
cord-018142-xt71w4nr	262	1	Various	various	JJ
cord-018142-xt71w4nr	262	2	mechanisms	mechanism	NNS
cord-018142-xt71w4nr	262	3	can	can	MD
cord-018142-xt71w4nr	262	4	be	be	VB
cord-018142-xt71w4nr	262	5	responsible	responsible	JJ
cord-018142-xt71w4nr	262	6	:	:	:
cord-018142-xt71w4nr	262	7	z	z	LS
cord-018142-xt71w4nr	262	8	development	development	NN
cord-018142-xt71w4nr	262	9	of	of	IN
cord-018142-xt71w4nr	262	10	anti	anti	JJ
cord-018142-xt71w4nr	262	11	-	-	JJ
cord-018142-xt71w4nr	262	12	ADAMTS-13	adamts-13	JJ
cord-018142-xt71w4nr	262	13	auto	auto	NN
cord-018142-xt71w4nr	262	14	-	-	HYPH
cord-018142-xt71w4nr	262	15	antibodies	antibody	NNS
cord-018142-xt71w4nr	262	16	responsible	responsible	JJ
cord-018142-xt71w4nr	262	17	for	for	IN
cord-018142-xt71w4nr	262	18	TTP	TTP	NNP
cord-018142-xt71w4nr	262	19	that	that	WDT
cord-018142-xt71w4nr	262	20	responds	respond	VBZ
cord-018142-xt71w4nr	262	21	favorably	favorably	RB
cord-018142-xt71w4nr	262	22	to	to	IN
cord-018142-xt71w4nr	262	23	treatment	treatment	NN
cord-018142-xt71w4nr	262	24	z	z	NN
cord-018142-xt71w4nr	263	1	a	a	DT
cord-018142-xt71w4nr	263	2	multifactorial	multifactorial	JJ
cord-018142-xt71w4nr	263	3	origin	origin	NN
cord-018142-xt71w4nr	263	4	(	(	-LRB-
cord-018142-xt71w4nr	263	5	opportunistic	opportunistic	JJ
cord-018142-xt71w4nr	263	6	CMV	CMV	NNP
cord-018142-xt71w4nr	263	7	infection	infection	NN
cord-018142-xt71w4nr	263	8	[	[	-LRB-
cord-018142-xt71w4nr	263	9	44	44	CD
cord-018142-xt71w4nr	263	10	]	]	-RRB-
cord-018142-xt71w4nr	263	11	)	)	-RRB-
cord-018142-xt71w4nr	263	12	,	,	,
cord-018142-xt71w4nr	263	13	drugs	drug	NNS
cord-018142-xt71w4nr	263	14	(	(	-LRB-
cord-018142-xt71w4nr	263	15	valaciclovir	valaciclovir	NNP
cord-018142-xt71w4nr	263	16	,	,	,
cord-018142-xt71w4nr	263	17	etc	etc	FW
cord-018142-xt71w4nr	263	18	.	.	.
cord-018142-xt71w4nr	263	19	)	)	-RRB-
cord-018142-xt71w4nr	264	1	with	with	IN
cord-018142-xt71w4nr	264	2	a	a	DT
cord-018142-xt71w4nr	264	3	more	more	RBR
cord-018142-xt71w4nr	264	4	variable	variable	JJ
cord-018142-xt71w4nr	264	5	response	response	NN
cord-018142-xt71w4nr	264	6	to	to	IN
cord-018142-xt71w4nr	264	7	treatment	treatment	NN
cord-018142-xt71w4nr	264	8	and	and	CC
cord-018142-xt71w4nr	264	9	a	a	DT
cord-018142-xt71w4nr	264	10	poorer	poor	JJR
cord-018142-xt71w4nr	264	11	prognosis	prognosis	NN
cord-018142-xt71w4nr	264	12	.	.	.
cord-018142-xt71w4nr	265	1	Treatment	treatment	NN
cord-018142-xt71w4nr	265	2	of	of	IN
cord-018142-xt71w4nr	265	3	this	this	DT
cord-018142-xt71w4nr	265	4	type	type	NN
cord-018142-xt71w4nr	265	5	of	of	IN
cord-018142-xt71w4nr	265	6	TMA	TMA	NNP
cord-018142-xt71w4nr	265	7	syndrome	syndrome	NN
cord-018142-xt71w4nr	265	8	must	must	MD
cord-018142-xt71w4nr	265	9	be	be	VB
cord-018142-xt71w4nr	265	10	associated	associate	VBN
cord-018142-xt71w4nr	265	11	with	with	IN
cord-018142-xt71w4nr	265	12	antiretroviral	antiretroviral	JJ
cord-018142-xt71w4nr	265	13	therapy	therapy	NN
cord-018142-xt71w4nr	265	14	.	.	.
cord-018142-xt71w4nr	266	1	Other	other	JJ
cord-018142-xt71w4nr	266	2	diseases	disease	NNS
cord-018142-xt71w4nr	266	3	have	have	VBP
cord-018142-xt71w4nr	266	4	also	also	RB
cord-018142-xt71w4nr	266	5	been	be	VBN
cord-018142-xt71w4nr	266	6	associated	associate	VBN
cord-018142-xt71w4nr	266	7	with	with	IN
cord-018142-xt71w4nr	266	8	TMA	TMA	NNP
cord-018142-xt71w4nr	266	9	disorders	disorder	NNS
cord-018142-xt71w4nr	266	10	,	,	,
cord-018142-xt71w4nr	266	11	including	include	VBG
cord-018142-xt71w4nr	266	12	catastrophic	catastrophic	JJ
cord-018142-xt71w4nr	266	13	antiphospholipid	antiphospholipid	NNP
cord-018142-xt71w4nr	266	14	syndrome	syndrome	NN
cord-018142-xt71w4nr	266	15	,	,	,
cord-018142-xt71w4nr	266	16	veno	veno	NNP
cord-018142-xt71w4nr	266	17	-	-	HYPH
cord-018142-xt71w4nr	266	18	occlusive	occlusive	JJ
cord-018142-xt71w4nr	266	19	disease	disease	NN
cord-018142-xt71w4nr	266	20	,	,	,
cord-018142-xt71w4nr	266	21	DIC	DIC	NNP
cord-018142-xt71w4nr	266	22	,	,	,
cord-018142-xt71w4nr	266	23	type	type	NN
cord-018142-xt71w4nr	266	24	2	2	CD
cord-018142-xt71w4nr	266	25	heparininduced	heparininduced	JJ
cord-018142-xt71w4nr	266	26	thrombocytopenia	thrombocytopenia	NN
cord-018142-xt71w4nr	266	27	,	,	,
cord-018142-xt71w4nr	266	28	giant	giant	JJ
cord-018142-xt71w4nr	266	29	hemangioma	hemangioma	NN
cord-018142-xt71w4nr	266	30	,	,	,
cord-018142-xt71w4nr	266	31	hemangio	hemangio	NNP
cord-018142-xt71w4nr	266	32	-	-	HYPH
cord-018142-xt71w4nr	266	33	endothelioma	endothelioma	NNS
cord-018142-xt71w4nr	266	34	,	,	,
cord-018142-xt71w4nr	266	35	and	and	CC
cord-018142-xt71w4nr	266	36	malignant	malignant	JJ
cord-018142-xt71w4nr	266	37	hypertension	hypertension	NN
cord-018142-xt71w4nr	266	38	.	.	.
cord-018142-xt71w4nr	267	1	These	these	DT
cord-018142-xt71w4nr	267	2	various	various	JJ
cord-018142-xt71w4nr	267	3	syndromes	syndrome	NNS
cord-018142-xt71w4nr	267	4	must	must	MD
cord-018142-xt71w4nr	267	5	be	be	VB
cord-018142-xt71w4nr	267	6	eliminated	eliminate	VBN
cord-018142-xt71w4nr	267	7	before	before	IN
cord-018142-xt71w4nr	267	8	initiating	initiate	VBG
cord-018142-xt71w4nr	267	9	plasma	plasma	NN
cord-018142-xt71w4nr	267	10	therapy	therapy	NN
cord-018142-xt71w4nr	267	11	.	.	.
cord-018142-xt71w4nr	268	1	z	z	NNP
cord-018142-xt71w4nr	269	1	Conclusion	Conclusion	NNP
cord-018142-xt71w4nr	269	2	Major	Major	NNP
cord-018142-xt71w4nr	269	3	studies	study	NNS
cord-018142-xt71w4nr	269	4	designed	design	VBN
cord-018142-xt71w4nr	269	5	to	to	TO
cord-018142-xt71w4nr	269	6	improve	improve	VB
cord-018142-xt71w4nr	269	7	our	-PRON-	PRP$
cord-018142-xt71w4nr	269	8	understanding	understanding	NN
cord-018142-xt71w4nr	269	9	of	of	IN
cord-018142-xt71w4nr	269	10	the	the	DT
cord-018142-xt71w4nr	269	11	pathophysiology	pathophysiology	NN
cord-018142-xt71w4nr	269	12	of	of	IN
cord-018142-xt71w4nr	269	13	TMA	TMA	NNP
cord-018142-xt71w4nr	269	14	have	have	VBP
cord-018142-xt71w4nr	269	15	been	be	VBN
cord-018142-xt71w4nr	269	16	conducted	conduct	VBN
cord-018142-xt71w4nr	269	17	over	over	IN
cord-018142-xt71w4nr	269	18	recent	recent	JJ
cord-018142-xt71w4nr	269	19	years	year	NNS
cord-018142-xt71w4nr	269	20	.	.	.
cord-018142-xt71w4nr	270	1	This	this	DT
cord-018142-xt71w4nr	270	2	improved	improve	VBN
cord-018142-xt71w4nr	270	3	knowledge	knowledge	NN
cord-018142-xt71w4nr	270	4	opens	open	VBZ
cord-018142-xt71w4nr	270	5	up	up	RP
cord-018142-xt71w4nr	270	6	new	new	JJ
cord-018142-xt71w4nr	270	7	perspectives	perspective	NNS
cord-018142-xt71w4nr	270	8	for	for	IN
cord-018142-xt71w4nr	270	9	more	more	RBR
cord-018142-xt71w4nr	270	10	targeted	target	VBN
cord-018142-xt71w4nr	270	11	treatment	treatment	NN
cord-018142-xt71w4nr	270	12	.	.	.
cord-018142-xt71w4nr	271	1	However	however	RB
cord-018142-xt71w4nr	271	2	,	,	,
cord-018142-xt71w4nr	271	3	until	until	IN
cord-018142-xt71w4nr	271	4	these	these	DT
cord-018142-xt71w4nr	271	5	innovative	innovative	JJ
cord-018142-xt71w4nr	271	6	treatments	treatment	NNS
cord-018142-xt71w4nr	271	7	become	become	VBP
cord-018142-xt71w4nr	271	8	available	available	JJ
cord-018142-xt71w4nr	271	9	,	,	,
cord-018142-xt71w4nr	271	10	early	early	JJ
cord-018142-xt71w4nr	271	11	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	271	12	of	of	IN
cord-018142-xt71w4nr	271	13	these	these	DT
cord-018142-xt71w4nr	271	14	diseases	disease	NNS
cord-018142-xt71w4nr	271	15	is	be	VBZ
cord-018142-xt71w4nr	271	16	essential	essential	JJ
cord-018142-xt71w4nr	271	17	in	in	IN
cord-018142-xt71w4nr	271	18	order	order	NN
cord-018142-xt71w4nr	271	19	to	to	TO
cord-018142-xt71w4nr	271	20	rapidly	rapidly	RB
cord-018142-xt71w4nr	271	21	initiate	initiate	VB
cord-018142-xt71w4nr	271	22	specific	specific	JJ
cord-018142-xt71w4nr	271	23	treatment	treatment	NN
cord-018142-xt71w4nr	271	24	,	,	,
cord-018142-xt71w4nr	271	25	as	as	IN
cord-018142-xt71w4nr	271	26	the	the	DT
cord-018142-xt71w4nr	271	27	interval	interval	NN
cord-018142-xt71w4nr	271	28	between	between	IN
cord-018142-xt71w4nr	271	29	diagnosis	diagnosis	NN
cord-018142-xt71w4nr	271	30	and	and	CC
cord-018142-xt71w4nr	271	31	initiation	initiation	NN
cord-018142-xt71w4nr	271	32	of	of	IN
cord-018142-xt71w4nr	271	33	plasma	plasma	NN
cord-018142-xt71w4nr	271	34	exchange	exchange	NN
cord-018142-xt71w4nr	271	35	is	be	VBZ
cord-018142-xt71w4nr	271	36	a	a	DT
cord-018142-xt71w4nr	271	37	decisive	decisive	JJ
cord-018142-xt71w4nr	271	38	element	element	NN
cord-018142-xt71w4nr	271	39	in	in	IN
cord-018142-xt71w4nr	271	40	the	the	DT
cord-018142-xt71w4nr	271	41	prognosis	prognosis	NN
cord-018142-xt71w4nr	271	42	of	of	IN
cord-018142-xt71w4nr	271	43	TTP	TTP	NNP
cord-018142-xt71w4nr	271	44	.	.	.
cord-018142-xt71w4nr	272	1	Treatment	treatment	NN
cord-018142-xt71w4nr	272	2	must	must	MD
cord-018142-xt71w4nr	272	3	not	not	RB
cord-018142-xt71w4nr	272	4	be	be	VB
cord-018142-xt71w4nr	272	5	stopped	stop	VBN
cord-018142-xt71w4nr	272	6	too	too	RB
cord-018142-xt71w4nr	272	7	early	early	RB
cord-018142-xt71w4nr	272	8	or	or	CC
cord-018142-xt71w4nr	272	9	too	too	RB
cord-018142-xt71w4nr	272	10	rapidly	rapidly	RB
cord-018142-xt71w4nr	272	11	and	and	CC
cord-018142-xt71w4nr	272	12	must	must	MD
cord-018142-xt71w4nr	272	13	take	take	VB
cord-018142-xt71w4nr	272	14	into	into	IN
cord-018142-xt71w4nr	272	15	account	account	NN
cord-018142-xt71w4nr	272	16	the	the	DT
cord-018142-xt71w4nr	272	17	various	various	JJ
cord-018142-xt71w4nr	272	18	associated	associate	VBN
cord-018142-xt71w4nr	272	19	factors	factor	NNS
cord-018142-xt71w4nr	272	20	,	,	,
cord-018142-xt71w4nr	272	21	especially	especially	RB
cord-018142-xt71w4nr	272	22	the	the	DT
cord-018142-xt71w4nr	272	23	presence	presence	NN
cord-018142-xt71w4nr	272	24	of	of	IN
cord-018142-xt71w4nr	272	25	infection	infection	NN
cord-018142-xt71w4nr	272	26	.	.	.
cord-018142-xt71w4nr	273	1	Infectious	infectious	JJ
cord-018142-xt71w4nr	273	2	diseases	disease	NNS
cord-018142-xt71w4nr	273	3	as	as	IN
cord-018142-xt71w4nr	273	4	a	a	DT
cord-018142-xt71w4nr	273	5	trigger	trigger	NN
cord-018142-xt71w4nr	273	6	in	in	IN
cord-018142-xt71w4nr	273	7	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	273	8	microangiopathies	microangiopathie	NNS
cord-018142-xt71w4nr	273	9	in	in	IN
cord-018142-xt71w4nr	273	10	intensive	intensive	JJ
cord-018142-xt71w4nr	273	11	care	care	NN
cord-018142-xt71w4nr	273	12	unit	unit	NN
cord-018142-xt71w4nr	273	13	(	(	-LRB-
cord-018142-xt71w4nr	273	14	ICU	ICU	NNP
cord-018142-xt71w4nr	273	15	)	)	-RRB-
cord-018142-xt71w4nr	273	16	patients	patient	NNS
cord-018142-xt71w4nr	273	17	?	?	.
cord-018142-xt71w4nr	274	1	Thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	274	2	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	274	3	purpura	purpura	NN
cord-018142-xt71w4nr	274	4	and	and	CC
cord-018142-xt71w4nr	274	5	other	other	JJ
cord-018142-xt71w4nr	274	6	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	274	7	microangiopathy	microangiopathy	NNP
cord-018142-xt71w4nr	274	8	syndromes	syndromes	NNP
cord-018142-xt71w4nr	274	9	Purification	Purification	NNP
cord-018142-xt71w4nr	274	10	of	of	IN
cord-018142-xt71w4nr	274	11	human	human	NN
cord-018142-xt71w4nr	274	12	von	von	NNP
cord-018142-xt71w4nr	274	13	Willebrand	Willebrand	NNP
cord-018142-xt71w4nr	274	14	factor	factor	NN
cord-018142-xt71w4nr	274	15	-	-	HYPH
cord-018142-xt71w4nr	274	16	cleaving	cleave	VBG
cord-018142-xt71w4nr	274	17	protease	protease	NN
cord-018142-xt71w4nr	274	18	and	and	CC
cord-018142-xt71w4nr	274	19	its	-PRON-	PRP$
cord-018142-xt71w4nr	274	20	identification	identification	NN
cord-018142-xt71w4nr	274	21	as	as	IN
cord-018142-xt71w4nr	274	22	a	a	DT
cord-018142-xt71w4nr	274	23	new	new	JJ
cord-018142-xt71w4nr	274	24	member	member	NN
cord-018142-xt71w4nr	274	25	of	of	IN
cord-018142-xt71w4nr	274	26	the	the	DT
cord-018142-xt71w4nr	274	27	metalloproteinase	metalloproteinase	NN
cord-018142-xt71w4nr	274	28	family	family	NN
cord-018142-xt71w4nr	274	29	Partial	partial	JJ
cord-018142-xt71w4nr	274	30	amino	amino	NN
cord-018142-xt71w4nr	274	31	acid	acid	NN
cord-018142-xt71w4nr	274	32	sequence	sequence	NN
cord-018142-xt71w4nr	274	33	of	of	IN
cord-018142-xt71w4nr	274	34	purified	purify	VBN
cord-018142-xt71w4nr	274	35	von	von	NNP
cord-018142-xt71w4nr	274	36	Willebrand	Willebrand	NNP
cord-018142-xt71w4nr	274	37	factor	factor	NN
cord-018142-xt71w4nr	274	38	-	-	HYPH
cord-018142-xt71w4nr	274	39	cleaving	cleave	VBG
cord-018142-xt71w4nr	274	40	protease	protease	NN
cord-018142-xt71w4nr	274	41	Thrombotic	Thrombotic	NNP
cord-018142-xt71w4nr	274	42	microangiopathies	microangiopathie	NNS
cord-018142-xt71w4nr	274	43	Willebrand	Willebrand	NNP
cord-018142-xt71w4nr	274	44	factor	factor	NN
cord-018142-xt71w4nr	274	45	-	-	HYPH
cord-018142-xt71w4nr	274	46	cleaving	cleave	VBG
cord-018142-xt71w4nr	274	47	protease	protease	NN
cord-018142-xt71w4nr	274	48	in	in	IN
cord-018142-xt71w4nr	274	49	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	274	50	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	274	51	purpura	purpura	NN
cord-018142-xt71w4nr	274	52	and	and	CC
cord-018142-xt71w4nr	274	53	the	the	DT
cord-018142-xt71w4nr	274	54	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	274	55	-	-	HYPH
cord-018142-xt71w4nr	274	56	uremic	uremic	NN
cord-018142-xt71w4nr	274	57	syndrome	syndrome	NN
cord-018142-xt71w4nr	274	58	Mutations	Mutations	NNPS
cord-018142-xt71w4nr	274	59	in	in	IN
cord-018142-xt71w4nr	274	60	a	a	DT
cord-018142-xt71w4nr	274	61	member	member	NN
cord-018142-xt71w4nr	274	62	of	of	IN
cord-018142-xt71w4nr	274	63	the	the	DT
cord-018142-xt71w4nr	274	64	ADAMTS	ADAMTS	NNP
cord-018142-xt71w4nr	274	65	gene	gene	NN
cord-018142-xt71w4nr	274	66	family	family	NN
cord-018142-xt71w4nr	275	1	cause	cause	VB
cord-018142-xt71w4nr	275	2	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	275	3	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	275	4	purpura	purpura	NN
cord-018142-xt71w4nr	275	5	Willebrand	Willebrand	NNP
cord-018142-xt71w4nr	275	6	factor	factor	NN
cord-018142-xt71w4nr	275	7	cleaving	cleave	VBG
cord-018142-xt71w4nr	275	8	protease	protease	NN
cord-018142-xt71w4nr	275	9	(	(	-LRB-
cord-018142-xt71w4nr	275	10	ADAMTS13	ADAMTS13	NNP
cord-018142-xt71w4nr	275	11	)	)	-RRB-
cord-018142-xt71w4nr	275	12	is	be	VBZ
cord-018142-xt71w4nr	275	13	deficient	deficient	JJ
cord-018142-xt71w4nr	275	14	in	in	IN
cord-018142-xt71w4nr	275	15	recurrent	recurrent	JJ
cord-018142-xt71w4nr	275	16	and	and	CC
cord-018142-xt71w4nr	275	17	familial	familial	JJ
cord-018142-xt71w4nr	275	18	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	275	19	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	275	20	purpura	purpura	NN
cord-018142-xt71w4nr	275	21	and	and	CC
cord-018142-xt71w4nr	275	22	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	275	23	uremic	uremic	JJ
cord-018142-xt71w4nr	275	24	syndrome	syndrome	NN
cord-018142-xt71w4nr	275	25	Antibodies	Antibodies	NNP
cord-018142-xt71w4nr	275	26	to	to	TO
cord-018142-xt71w4nr	275	27	von	von	NNP
cord-018142-xt71w4nr	275	28	Willebrand	Willebrand	NNP
cord-018142-xt71w4nr	275	29	factor	factor	NN
cord-018142-xt71w4nr	275	30	-	-	HYPH
cord-018142-xt71w4nr	275	31	cleaving	cleave	VBG
cord-018142-xt71w4nr	275	32	protease	protease	NN
cord-018142-xt71w4nr	275	33	in	in	IN
cord-018142-xt71w4nr	275	34	acute	acute	JJ
cord-018142-xt71w4nr	275	35	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	275	36	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	275	37	purpura	purpura	NN
cord-018142-xt71w4nr	275	38	Specific	Specific	NNP
cord-018142-xt71w4nr	275	39	von	von	NNP
cord-018142-xt71w4nr	275	40	Willebrand	Willebrand	NNP
cord-018142-xt71w4nr	275	41	factor	factor	NN
cord-018142-xt71w4nr	275	42	-	-	HYPH
cord-018142-xt71w4nr	275	43	cleaving	cleave	VBG
cord-018142-xt71w4nr	275	44	protease	protease	NN
cord-018142-xt71w4nr	275	45	in	in	IN
cord-018142-xt71w4nr	275	46	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	275	47	microangiopathies	microangiopathie	NNS
cord-018142-xt71w4nr	275	48	:	:	:
cord-018142-xt71w4nr	276	1	a	a	DT
cord-018142-xt71w4nr	276	2	study	study	NN
cord-018142-xt71w4nr	276	3	of	of	IN
cord-018142-xt71w4nr	276	4	111	111	CD
cord-018142-xt71w4nr	276	5	cases	case	NNS
cord-018142-xt71w4nr	277	1	Outcome	outcome	NN
cord-018142-xt71w4nr	277	2	of	of	IN
cord-018142-xt71w4nr	277	3	severe	severe	JJ
cord-018142-xt71w4nr	277	4	adult	adult	NN
cord-018142-xt71w4nr	277	5	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	277	6	microangiopathies	microangiopathie	NNS
cord-018142-xt71w4nr	277	7	in	in	IN
cord-018142-xt71w4nr	277	8	the	the	DT
cord-018142-xt71w4nr	277	9	intensive	intensive	JJ
cord-018142-xt71w4nr	277	10	care	care	NN
cord-018142-xt71w4nr	277	11	unit	unit	NN
cord-018142-xt71w4nr	277	12	Human	human	JJ
cord-018142-xt71w4nr	277	13	immunodeficiency	immunodeficiency	NN
cord-018142-xt71w4nr	277	14	virus	virus	NN
cord-018142-xt71w4nr	277	15	infection	infection	NN
cord-018142-xt71w4nr	277	16	and	and	CC
cord-018142-xt71w4nr	277	17	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	277	18	microangiopathy	microangiopathy	NN
cord-018142-xt71w4nr	278	1	Thrombotic	Thrombotic	NNP
cord-018142-xt71w4nr	278	2	microangiopathy	microangiopathy	NN
cord-018142-xt71w4nr	278	3	in	in	IN
cord-018142-xt71w4nr	278	4	association	association	NN
cord-018142-xt71w4nr	278	5	with	with	IN
cord-018142-xt71w4nr	278	6	cytomegalovirus	cytomegalovirus	NNP
cord-018142-xt71w4nr	278	7	infection	infection	NN
cord-018142-xt71w4nr	278	8	in	in	IN
cord-018142-xt71w4nr	278	9	a	a	DT
cord-018142-xt71w4nr	278	10	renal	renal	JJ
cord-018142-xt71w4nr	278	11	transplant	transplant	NN
cord-018142-xt71w4nr	278	12	patient	patient	NN
cord-018142-xt71w4nr	278	13	:	:	:
cord-018142-xt71w4nr	278	14	a	a	DT
cord-018142-xt71w4nr	278	15	new	new	JJ
cord-018142-xt71w4nr	278	16	treatment	treatment	NN
cord-018142-xt71w4nr	278	17	strategy	strategy	NN
cord-018142-xt71w4nr	278	18	Cryptococcal	Cryptococcal	NNP
cord-018142-xt71w4nr	278	19	meningitis	meningitis	NN
cord-018142-xt71w4nr	278	20	following	follow	VBG
cord-018142-xt71w4nr	278	21	a	a	DT
cord-018142-xt71w4nr	278	22	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	278	23	microangiopathy	microangiopathy	NN
cord-018142-xt71w4nr	278	24	in	in	IN
cord-018142-xt71w4nr	278	25	an	an	DT
cord-018142-xt71w4nr	278	26	unrelated	unrelated	JJ
cord-018142-xt71w4nr	278	27	donor	donor	NN
cord-018142-xt71w4nr	278	28	bone	bone	NN
cord-018142-xt71w4nr	278	29	marrow	marrow	NN
cord-018142-xt71w4nr	278	30	transplant	transplant	NN
cord-018142-xt71w4nr	278	31	recipient	recipient	NN
cord-018142-xt71w4nr	278	32	Hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	278	33	-	-	HYPH
cord-018142-xt71w4nr	278	34	uremic	uremic	NN
cord-018142-xt71w4nr	278	35	syndrome	syndrome	NN
cord-018142-xt71w4nr	278	36	associated	associate	VBN
cord-018142-xt71w4nr	278	37	with	with	IN
cord-018142-xt71w4nr	278	38	pneumococcal	pneumococcal	JJ
cord-018142-xt71w4nr	278	39	sepsis	sepsis	NN
cord-018142-xt71w4nr	279	1	Thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	279	2	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	279	3	purpura	purpura	NN
cord-018142-xt71w4nr	279	4	complicating	complicate	VBG
cord-018142-xt71w4nr	279	5	Legionnaires	Legionnaires	NNPS
cord-018142-xt71w4nr	279	6	'	'	POS
cord-018142-xt71w4nr	279	7	disease	disease	NN
cord-018142-xt71w4nr	279	8	Thrombotic	Thrombotic	NNP
cord-018142-xt71w4nr	279	9	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	279	10	purpura	purpura	NN
cord-018142-xt71w4nr	279	11	and	and	CC
cord-018142-xt71w4nr	279	12	herpes	herpes	NNP
cord-018142-xt71w4nr	279	13	zoster	zoster	NNP
cord-018142-xt71w4nr	279	14	infection	infection	NN
cord-018142-xt71w4nr	280	1	Thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	280	2	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	280	3	purpura	purpura	NN
cord-018142-xt71w4nr	280	4	(	(	-LRB-
cord-018142-xt71w4nr	280	5	TTP	TTP	NNP
cord-018142-xt71w4nr	280	6	)	)	-RRB-
cord-018142-xt71w4nr	280	7	associated	associate	VBN
cord-018142-xt71w4nr	280	8	with	with	IN
cord-018142-xt71w4nr	280	9	a	a	DT
cord-018142-xt71w4nr	280	10	Borrelia	Borrelia	NNP
cord-018142-xt71w4nr	280	11	burgdorferi	burgdorferi	NN
cord-018142-xt71w4nr	280	12	infection	infection	NN
cord-018142-xt71w4nr	280	13	Thrombotic	Thrombotic	NNP
cord-018142-xt71w4nr	280	14	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	280	15	purpura	purpura	NN
cord-018142-xt71w4nr	280	16	associated	associate	VBN
cord-018142-xt71w4nr	280	17	with	with	IN
cord-018142-xt71w4nr	280	18	Bacteroides	Bacteroides	NNP
cord-018142-xt71w4nr	280	19	bacteremia	bacteremia	NN
cord-018142-xt71w4nr	280	20	Thrombotic	Thrombotic	NNP
cord-018142-xt71w4nr	280	21	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	280	22	purpura	purpura	NN
cord-018142-xt71w4nr	280	23	associated	associate	VBN
cord-018142-xt71w4nr	280	24	with	with	IN
cord-018142-xt71w4nr	280	25	primary	primary	JJ
cord-018142-xt71w4nr	280	26	tuberculosis	tuberculosis	NN
cord-018142-xt71w4nr	280	27	Hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	280	28	uremic	uremic	JJ
cord-018142-xt71w4nr	280	29	syndrome	syndrome	NN
cord-018142-xt71w4nr	281	1	Insuffisances	Insuffisances	NNP
cord-018142-xt71w4nr	281	2	rnales	rnales	NNP
cord-018142-xt71w4nr	281	3	aigus	aigus	NNP
cord-018142-xt71w4nr	281	4	d'origine	d'origine	NNP
cord-018142-xt71w4nr	281	5	glomrulaire	glomrulaire	NNP
cord-018142-xt71w4nr	281	6	et	et	NNP
cord-018142-xt71w4nr	281	7	vasculaire	vasculaire	JJ
cord-018142-xt71w4nr	281	8	Recurrent	recurrent	JJ
cord-018142-xt71w4nr	281	9	haemolytic	haemolytic	JJ
cord-018142-xt71w4nr	281	10	uraemic	uraemic	NNP
cord-018142-xt71w4nr	281	11	syndrome	syndrome	NN
cord-018142-xt71w4nr	281	12	and	and	CC
cord-018142-xt71w4nr	281	13	acquired	acquire	VBD
cord-018142-xt71w4nr	281	14	hypomorphic	hypomorphic	JJ
cord-018142-xt71w4nr	281	15	variant	variant	NN
cord-018142-xt71w4nr	281	16	of	of	IN
cord-018142-xt71w4nr	281	17	the	the	DT
cord-018142-xt71w4nr	281	18	third	third	JJ
cord-018142-xt71w4nr	281	19	component	component	NN
cord-018142-xt71w4nr	281	20	of	of	IN
cord-018142-xt71w4nr	281	21	complement	complement	JJ
cord-018142-xt71w4nr	281	22	Heterozygous	heterozygous	JJ
cord-018142-xt71w4nr	281	23	and	and	CC
cord-018142-xt71w4nr	281	24	homozygous	homozygous	JJ
cord-018142-xt71w4nr	281	25	factor	factor	NN
cord-018142-xt71w4nr	282	1	h	h	NNP
cord-018142-xt71w4nr	282	2	deficiencies	deficiency	NNS
cord-018142-xt71w4nr	282	3	associated	associate	VBN
cord-018142-xt71w4nr	282	4	with	with	IN
cord-018142-xt71w4nr	282	5	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	282	6	uremic	uremic	JJ
cord-018142-xt71w4nr	282	7	syndrome	syndrome	NN
cord-018142-xt71w4nr	282	8	or	or	CC
cord-018142-xt71w4nr	282	9	membranoproliferative	membranoproliferative	JJ
cord-018142-xt71w4nr	282	10	glomerulonephritis	glomerulonephritis	NN
cord-018142-xt71w4nr	282	11	:	:	:
cord-018142-xt71w4nr	282	12	report	report	NN
cord-018142-xt71w4nr	282	13	and	and	CC
cord-018142-xt71w4nr	282	14	genetic	genetic	JJ
cord-018142-xt71w4nr	282	15	analysis	analysis	NN
cord-018142-xt71w4nr	282	16	of	of	IN
cord-018142-xt71w4nr	282	17	16	16	CD
cord-018142-xt71w4nr	282	18	cases	case	NNS
cord-018142-xt71w4nr	282	19	Plasma	plasma	NN
cord-018142-xt71w4nr	282	20	exchange	exchange	NN
cord-018142-xt71w4nr	282	21	for	for	IN
cord-018142-xt71w4nr	282	22	treatment	treatment	NN
cord-018142-xt71w4nr	282	23	of	of	IN
cord-018142-xt71w4nr	282	24	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	282	25	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	282	26	purpura	purpura	NN
cord-018142-xt71w4nr	282	27	in	in	IN
cord-018142-xt71w4nr	282	28	critically	critically	RB
cord-018142-xt71w4nr	282	29	ill	ill	JJ
cord-018142-xt71w4nr	282	30	patients	patient	NNS
cord-018142-xt71w4nr	283	1	Purpura	purpura	NN
cord-018142-xt71w4nr	283	2	thrombotique	thrombotique	NN
cord-018142-xt71w4nr	283	3	thrombocytopnique	thrombocytopnique	NN
cord-018142-xt71w4nr	284	1	The	the	DT
cord-018142-xt71w4nr	284	2	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	284	3	uremic	uremic	JJ
cord-018142-xt71w4nr	284	4	syndrome	syndrome	NN
cord-018142-xt71w4nr	285	1	Recent	recent	JJ
cord-018142-xt71w4nr	285	2	advances	advance	NNS
cord-018142-xt71w4nr	285	3	in	in	IN
cord-018142-xt71w4nr	285	4	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	285	5	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	285	6	purpura	purpura	NN
cord-018142-xt71w4nr	285	7	Prothrombotic	Prothrombotic	NNP
cord-018142-xt71w4nr	285	8	coagulation	coagulation	NN
cord-018142-xt71w4nr	285	9	abnormalities	abnormality	NNS
cord-018142-xt71w4nr	285	10	preceding	precede	VBG
cord-018142-xt71w4nr	285	11	the	the	DT
cord-018142-xt71w4nr	285	12	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	285	13	-	-	HYPH
cord-018142-xt71w4nr	285	14	uremic	uremic	JJ
cord-018142-xt71w4nr	285	15	syndrome	syndrome	NN
cord-018142-xt71w4nr	285	16	Improved	improve	VBN
cord-018142-xt71w4nr	285	17	survival	survival	NN
cord-018142-xt71w4nr	285	18	in	in	IN
cord-018142-xt71w4nr	285	19	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	285	20	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	285	21	purpura	purpura	NN
cord-018142-xt71w4nr	285	22	-	-	HYPH
cord-018142-xt71w4nr	285	23	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	285	24	uremic	uremic	JJ
cord-018142-xt71w4nr	285	25	syndrome	syndrome	NN
cord-018142-xt71w4nr	285	26	.	.	.
cord-018142-xt71w4nr	286	1	Clinical	clinical	JJ
cord-018142-xt71w4nr	286	2	experience	experience	NN
cord-018142-xt71w4nr	286	3	in	in	IN
cord-018142-xt71w4nr	286	4	108	108	CD
cord-018142-xt71w4nr	286	5	patients	patient	NNS
cord-018142-xt71w4nr	286	6	Improved	improve	VBN
cord-018142-xt71w4nr	286	7	survival	survival	NN
cord-018142-xt71w4nr	286	8	with	with	IN
cord-018142-xt71w4nr	286	9	plasma	plasma	NN
cord-018142-xt71w4nr	286	10	exchange	exchange	NN
cord-018142-xt71w4nr	286	11	in	in	IN
cord-018142-xt71w4nr	286	12	patients	patient	NNS
cord-018142-xt71w4nr	286	13	with	with	IN
cord-018142-xt71w4nr	286	14	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	286	15	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	286	16	purpura	purpura	NN
cord-018142-xt71w4nr	286	17	-	-	HYPH
cord-018142-xt71w4nr	286	18	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	286	19	uremic	uremic	JJ
cord-018142-xt71w4nr	286	20	syndrome	syndrome	NN
cord-018142-xt71w4nr	286	21	Thrombotic	Thrombotic	NNP
cord-018142-xt71w4nr	286	22	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	286	23	purpura	purpura	NN
cord-018142-xt71w4nr	286	24	:	:	:
cord-018142-xt71w4nr	286	25	outcome	outcome	NN
cord-018142-xt71w4nr	286	26	in	in	IN
cord-018142-xt71w4nr	286	27	24	24	CD
cord-018142-xt71w4nr	286	28	patients	patient	NNS
cord-018142-xt71w4nr	286	29	with	with	IN
cord-018142-xt71w4nr	286	30	renal	renal	JJ
cord-018142-xt71w4nr	286	31	impairment	impairment	NN
cord-018142-xt71w4nr	286	32	treated	treat	VBN
cord-018142-xt71w4nr	286	33	with	with	IN
cord-018142-xt71w4nr	286	34	plasma	plasma	NN
cord-018142-xt71w4nr	286	35	exchange	exchange	NN
cord-018142-xt71w4nr	286	36	Thrombotic	Thrombotic	NNP
cord-018142-xt71w4nr	286	37	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	286	38	purpura/	purpura/	CD
cord-018142-xt71w4nr	286	39	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	286	40	uremic	uremic	JJ
cord-018142-xt71w4nr	286	41	syndrome	syndrome	NN
cord-018142-xt71w4nr	286	42	:	:	:
cord-018142-xt71w4nr	286	43	a	a	DT
cord-018142-xt71w4nr	286	44	multivariate	multivariate	JJ
cord-018142-xt71w4nr	286	45	analysis	analysis	NN
cord-018142-xt71w4nr	286	46	of	of	IN
cord-018142-xt71w4nr	286	47	factors	factor	NNS
cord-018142-xt71w4nr	286	48	predicting	predict	VBG
cord-018142-xt71w4nr	286	49	the	the	DT
cord-018142-xt71w4nr	286	50	response	response	NN
cord-018142-xt71w4nr	286	51	to	to	IN
cord-018142-xt71w4nr	286	52	plasma	plasma	NN
cord-018142-xt71w4nr	286	53	exchange	exchange	NN
cord-018142-xt71w4nr	286	54	High	high	JJ
cord-018142-xt71w4nr	286	55	incidence	incidence	NN
cord-018142-xt71w4nr	286	56	of	of	IN
cord-018142-xt71w4nr	286	57	relapses	relapse	NNS
cord-018142-xt71w4nr	286	58	in	in	IN
cord-018142-xt71w4nr	286	59	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	286	60	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	286	61	purpura	purpura	NN
cord-018142-xt71w4nr	286	62	.	.	.
cord-018142-xt71w4nr	287	1	Clinical	clinical	JJ
cord-018142-xt71w4nr	287	2	study	study	NN
cord-018142-xt71w4nr	287	3	of	of	IN
cord-018142-xt71w4nr	287	4	38	38	CD
cord-018142-xt71w4nr	287	5	patients	patient	NNS
cord-018142-xt71w4nr	287	6	Comparison	Comparison	NNP
cord-018142-xt71w4nr	287	7	of	of	IN
cord-018142-xt71w4nr	287	8	plasma	plasma	NN
cord-018142-xt71w4nr	287	9	exchange	exchange	NN
cord-018142-xt71w4nr	287	10	with	with	IN
cord-018142-xt71w4nr	287	11	plasma	plasma	NN
cord-018142-xt71w4nr	287	12	infusion	infusion	NN
cord-018142-xt71w4nr	287	13	in	in	IN
cord-018142-xt71w4nr	287	14	the	the	DT
cord-018142-xt71w4nr	287	15	treatment	treatment	NN
cord-018142-xt71w4nr	287	16	of	of	IN
cord-018142-xt71w4nr	287	17	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	287	18	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	287	19	purpura	purpura	NN
cord-018142-xt71w4nr	287	20	.	.	.
cord-018142-xt71w4nr	288	1	Canadian	Canadian	NNP
cord-018142-xt71w4nr	288	2	Apheresis	Apheresis	NNP
cord-018142-xt71w4nr	288	3	Study	Study	NNP
cord-018142-xt71w4nr	288	4	Group	Group	NNP
cord-018142-xt71w4nr	289	1	The	the	DT
cord-018142-xt71w4nr	289	2	risk	risk	NN
cord-018142-xt71w4nr	289	3	of	of	IN
cord-018142-xt71w4nr	289	4	the	the	DT
cord-018142-xt71w4nr	289	5	hemolytic	hemolytic	JJ
cord-018142-xt71w4nr	289	6	-	-	HYPH
cord-018142-xt71w4nr	289	7	uremic	uremic	NN
cord-018142-xt71w4nr	289	8	syndrome	syndrome	NN
cord-018142-xt71w4nr	289	9	after	after	IN
cord-018142-xt71w4nr	289	10	antibiotic	antibiotic	JJ
cord-018142-xt71w4nr	289	11	treatment	treatment	NN
cord-018142-xt71w4nr	289	12	of	of	IN
cord-018142-xt71w4nr	289	13	Escherichia	Escherichia	NNP
cord-018142-xt71w4nr	289	14	coli	coli	NNS
cord-018142-xt71w4nr	289	15	O157	O157	NNP
cord-018142-xt71w4nr	289	16	:	:	:
cord-018142-xt71w4nr	290	1	H7	H7	NNP
cord-018142-xt71w4nr	290	2	infections	infection	NNS
cord-018142-xt71w4nr	291	1	Thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	291	2	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	291	3	purpura	purpura	NN
cord-018142-xt71w4nr	291	4	:	:	:
cord-018142-xt71w4nr	292	1	early	early	JJ
cord-018142-xt71w4nr	292	2	and	and	CC
cord-018142-xt71w4nr	292	3	late	late	JJ
cord-018142-xt71w4nr	292	4	responders	responder	NNS
cord-018142-xt71w4nr	292	5	Rituximab	Rituximab	NNP
cord-018142-xt71w4nr	292	6	for	for	IN
cord-018142-xt71w4nr	292	7	chronic	chronic	JJ
cord-018142-xt71w4nr	292	8	recurring	recurring	JJ
cord-018142-xt71w4nr	292	9	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	292	10	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	292	11	purpura	purpura	NN
cord-018142-xt71w4nr	292	12	:	:	:
cord-018142-xt71w4nr	292	13	a	a	DT
cord-018142-xt71w4nr	292	14	case	case	NN
cord-018142-xt71w4nr	292	15	report	report	NN
cord-018142-xt71w4nr	292	16	and	and	CC
cord-018142-xt71w4nr	292	17	review	review	NN
cord-018142-xt71w4nr	292	18	of	of	IN
cord-018142-xt71w4nr	292	19	the	the	DT
cord-018142-xt71w4nr	292	20	literature	literature	NN
cord-018142-xt71w4nr	292	21	Treatment	treatment	NN
cord-018142-xt71w4nr	292	22	of	of	IN
cord-018142-xt71w4nr	292	23	plasma	plasma	NN
cord-018142-xt71w4nr	292	24	refractory	refractory	JJ
cord-018142-xt71w4nr	292	25	thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	292	26	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	292	27	purpura	purpura	NN
cord-018142-xt71w4nr	292	28	with	with	IN
cord-018142-xt71w4nr	292	29	protein	protein	NN
cord-018142-xt71w4nr	292	30	A	a	DT
cord-018142-xt71w4nr	292	31	immunoabsorption	immunoabsorption	NN
cord-018142-xt71w4nr	293	1	Thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	293	2	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	293	3	purpura	purpura	NN
cord-018142-xt71w4nr	293	4	associated	associate	VBN
cord-018142-xt71w4nr	293	5	with	with	IN
cord-018142-xt71w4nr	293	6	clopidogrel	clopidogrel	JJ
cord-018142-xt71w4nr	293	7	Thrombotic	thrombotic	JJ
cord-018142-xt71w4nr	293	8	thrombocytopenic	thrombocytopenic	JJ
cord-018142-xt71w4nr	293	9	purpura	purpura	NN
cord-018142-xt71w4nr	293	10	associated	associate	VBN
cord-018142-xt71w4nr	293	11	with	with	IN
cord-018142-xt71w4nr	293	12	ticlopidine	ticlopidine	NNP
cord-018142-xt71w4nr	293	13	.	.	.
cord-018142-xt71w4nr	294	1	A	a	DT
cord-018142-xt71w4nr	294	2	review	review	NN
cord-018142-xt71w4nr	294	3	of	of	IN
cord-018142-xt71w4nr	294	4	60	60	CD
cord-018142-xt71w4nr	294	5	cases	case	NNS
cord-018142-xt71w4nr	294	6	Hemostatic	hemostatic	JJ
cord-018142-xt71w4nr	294	7	abnormalities	abnormality	NNS
cord-018142-xt71w4nr	294	8	and	and	CC
cord-018142-xt71w4nr	294	9	increased	increase	VBD
cord-018142-xt71w4nr	294	10	vascular	vascular	JJ
cord-018142-xt71w4nr	294	11	endothelial	endothelial	JJ
cord-018142-xt71w4nr	294	12	cell	cell	NN
cord-018142-xt71w4nr	294	13	markers	marker	NNS
cord-018142-xt71w4nr	294	14	in	in	IN
cord-018142-xt71w4nr	294	15	patients	patient	NNS
cord-018142-xt71w4nr	294	16	with	with	IN
cord-018142-xt71w4nr	294	17	red	red	JJ
cord-018142-xt71w4nr	294	18	cell	cell	NN
cord-018142-xt71w4nr	294	19	fragmentation	fragmentation	NN
cord-018142-xt71w4nr	294	20	syndrome	syndrome	NN
cord-018142-xt71w4nr	294	21	induced	induce	VBN
cord-018142-xt71w4nr	294	22	by	by	IN
cord-018142-xt71w4nr	294	23	mitomycin	mitomycin	NNS
cord-018142-xt71w4nr	294	24	C	C	NNP
cord-018142-xt71w4nr	294	25	Thrombotic	Thrombotic	NNP
cord-018142-xt71w4nr	294	26	microangiopathy	microangiopathy	NN
cord-018142-xt71w4nr	294	27	and	and	CC
cord-018142-xt71w4nr	294	28	cytomegalovirus	cytomegalovirus	JJ
cord-018142-xt71w4nr	294	29	disease	disease	NN
cord-018142-xt71w4nr	294	30	in	in	IN
cord-018142-xt71w4nr	294	31	patients	patient	NNS
cord-018142-xt71w4nr	294	32	infected	infect	VBN
cord-018142-xt71w4nr	294	33	with	with	IN
cord-018142-xt71w4nr	294	34	human	human	JJ
cord-018142-xt71w4nr	294	35	immunodeficiency	immunodeficiency	NN
cord-018142-xt71w4nr	294	36	virus	virus	NN