id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-018408-ttae193b	Haddad, Imad Y.	Pneumonia and Empyema	2008-11-15		.txt	text/plain	6160	345	33	Second, patients with genetic or acquired immune defi ciency commonly develop severe pneumonia with opportunistic infections that usually do not infect healthy children. These immunocompromised patients commonly have been given chemo-radiotherapy for cancer or are receiving immune-suppressive agents to prevent rejection episodes following solid organ and hematopoietic stem cell transplantation. The pathogens that commonly produce CAP or VAP, such as Streptococcus pneumoniae, Gram-negative bacilli, and Staphylococcus aureus, are relatively virulent bacteria so that only a small inoculum is required and the aspiration is usually subtle. Bacterial organisms recovered from tracheal secretions obtained through an endotracheal tube may or may not refl ect the causative agent(s) responsible for lower respiratory tract infection. In addition, recipients of solid organ and hematopoietic stem cell transplantation (HSCT) are frequently given life-long treatment with immunosuppressive agents designed to prevent graft rejection or graft-versus-host disease. Early-onset nosocomial pneumonia and VAP are commonly caused by antibiotic-sensitive, community-acquired organisms (e.g., Strep.	./cache/cord-018408-ttae193b.txt	./txt/cord-018408-ttae193b.txt