id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-307638-fffjcnak	Waterer, Grant	Respiratory infections in the Asia‐Pacific region: Problems and cautious optimism	2017-12-21		.txt	text/plain	1394	73	44	Over the past 12 months, Respirology has published a series of excellent reviews outlining the challenges that respiratory infections continue to pose to the Asia-Pacific region and beyond. Equally, they argue that more resources are desperately needed to adequately control tuberculosis, and especially drug-resistant diseases, in the developing world. Rather than poverty, malnutrition and overcrowding driving the problem as with tuberculosis, frequent use and misuse of broadspectrum antibiotics in patients with a fundamental inability to resist infection (such as in those with severe chronic obstructive airway disease, bronchiectasis, cystic fibrosis or major organ failure requiring prolonged stays in intensive care units) are responsible for MDR-GNB. As Rodrigo-Troyano and Sibila point out, unlike tuberculosis, there has been very little progress in antibiotic development for MDR-GNB and case reports are increasing for pan-resistant organisms immune to all known therapies. Regional differences in antibiotic-resistant pathogens in patients with pneumonia: implications for clinicians	./cache/cord-307638-fffjcnak.txt	./txt/cord-307638-fffjcnak.txt