id author title date pages extension mime words sentences flesch summary cache txt cord-315449-kt4m3247 Wise, A.L. Public and Population Health Genomics 2016-06-10 .txt text/plain 3263 165 40 In this chapter we will survey the three major disciplines contributing to population genomics (genomics, population, and social sciences) and explore two cross-cutting issues: global health and population versus individual health, using specific examples from diseases such as asthma, colon cancer, and cystic fibrosis. This aspect of the emerging field of population genomics is discussed in this chapter using specific examples from diverse diseases such as breast cancer, colorectal cancer, bronchial asthma, Crohn disease, Alzheimer dementia, and cystic fibrosis. Population variation is an important consideration when studying common complex conditions that are influenced by multiple genetic, environmental, and social risk factors, such as bronchial asthma. For example, the prevalence of type 2 diabetes mellitus is increasing globally and has been associated with multiple genetic (more than 60 genes to date), epigenetic (such as methylation or histone modification), environmental (such as diet), and social factors (such as exercise), all of which contribute to this complex disease [42] . ./cache/cord-315449-kt4m3247.txt ./txt/cord-315449-kt4m3247.txt