id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-013046-r6dtiu97	Liu, Bin	Combining evolutionary information extracted from frequency profiles with sequence-based kernels for protein remote homology detection	2014-02-15		.txt	text/plain	6945	347	52	title: Combining evolutionary information extracted from frequency profiles with sequence-based kernels for protein remote homology detection For instance, the kernel combination methodology (VBKC) (Damoulas and Girolami, 2008 ) used a single multiclass kernel machine to combine various kernels based on different feature spaces; SVM-physicochemical distance transformation (PDT) (Liu et al., 2012) combined the amino acid physicochemical properties and the profile features via PDT to incorporate the local sequence-order information of the entire protein sequences. The results obtained by these four methods on the SCOP benchmark are listed in Supplementary Table S1 of Supplementary Material S4, from which we can see that the current method outperforms SVM-Top-n-gram-combine-LSA (Liu et al., 2008) , SVM-PDT-Profile (Liu et al., 2012) and BioSVM-2L (Muda et al., 2011) and is highly comparable with Profile (Kuang et al., 2005) and HHSearch (So¨ding, 2005) , indicating that the profile-based protein representation is a promising approach to extract the evolutionary information from frequency profiles for protein remote homology detection. Protein remote homology detection by combining Chou's pseudo amino acid composition and profile-based protein representation	./cache/cord-013046-r6dtiu97.txt	./txt/cord-013046-r6dtiu97.txt