id author title date pages extension mime words sentences flesch summary cache txt cord-024989-0o6agnrc Li, Qihao Prediction and analysis of key protein structures of 2019-nCoV 2020-05-12 .txt text/plain 3244 172 58 Aim: The purpose of this study was to predict and analyze the structure and function of 2019-novel Coronavirus (nCoV) key proteins. Differential key protein structure analysis of 2019-nCoV Although some amino acids were inserted in two positions of nsp3 in orf1ab [23] , the insertion sites were in the nsp3b and nsp3c regions, which are mainly related to the binding reaction of nucleic acids. Back-mutating mutant amino acids to study the functional change of RBD of S protein In order to study the effect of interactional amino acid changes in 2019-nCoV-ACE2 binding region RBD, we mutated the changed three amino acid residues (Glu 470 , Gln 484 and Asn 487 ) within the RBD structure back to the original amino acids. • We elaborated the sequence and structure differences in each key protein of 2019-nCoV and other bat SARS coronaviruses (CoVs). ./cache/cord-024989-0o6agnrc.txt ./txt/cord-024989-0o6agnrc.txt