id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-252304-lwiulri7	Fragnoud, Romain	Differential proteomic analysis of virus-enriched fractions obtained from plasma pools of patients with dengue fever or severe dengue	2015-11-14		.txt	text/plain	8324	433	46	ELISAs were used to validate differential expression of a selection of identified host proteins in individual plasma samples of patients with dengue fever compared to patients with severe dengue. CONCLUSION: A novel technique of virion-enrichment from plasma has allowed to identify two host proteins that have prognostic value for classifying patients with acute dengue who are more likely to develop a severe dengue. Fig. 2 Ingenuity Pathway Analysis for host proteins identified in the viral-enriched plasma fraction of patients with dengue. To validate the mass spectrometry data, the levels of selected host proteins were assessed by quantitative ELISA both in the virus-enriched fraction and in individual plasma samples from DF or SD patients. In this regard, further studies are required to assess the prognostic value of host proteins associated with inflammation, complement cascade and coagulation for disease severity by analysis of additional biological samples from patients infected with DV.	./cache/cord-252304-lwiulri7.txt	./txt/cord-252304-lwiulri7.txt