id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-319609-y0gdjn64	Van Duyne, Rachel	The identification of unique serum proteins of HIV-1 latently infected long-term non-progressor patients	2010-07-06		.txt	text/plain	8544	356	47	In particular, the analysis of HIV-1 infected serum is an attractive medium with which to identify altered protein expression due to the ease and non-invasive methods of collecting samples as well as the corresponding insight into the in vivo interaction of the virus with infected cells/tissue. We have analyzed and compared serum samples from HIV-1 infected subjects who are being treated using highly active antiretroviral therapy (HAART) to those who are latently infected but have not progressed to AIDS despite the absence of treatment, i.e. long term non-progressors (LTNPs). In order to gain insight into the reason why p16 INK4A may be present preferentially in the serum of LTNP patients, we treated latently infected HIV-1 cell lines (J1.1 and U1) with exogenous purified GST-p16 INK4A Figure 4A depicts an RT assay which measures the viral reverse transcriptase activity of infected cells and is an indicator of functional particle production.	./cache/cord-319609-y0gdjn64.txt	./txt/cord-319609-y0gdjn64.txt