id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-339333-7tpnbr8q	CHEN, YUXIAN	Comparative serum proteome expression of the steroid-induced femoral head osteonecrosis in adults	2014-11-12		.txt	text/plain	3615	211	47	The differentially-expressed protein spots were subjected to in-gel trypsin digestion followed by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. The purpose of the present study is to find potential biomarkers of the SONFH by using proteomic technology to analyze serum protein profiles in patients with SONFH and the healthy control group. To ensure the reproducibility, accuracy and objectivity of the experiments, the following steps were Differentially-expressed protein spots were identified from the two-dimensional difference gel electrophoresis profiling of human plasma, with a lower abundance in the steroid-induced femoral head osteonecrosis group compared to the control group. In the present study, four proteins (C3, C4, ITIH4 and A2MG) showed lower expression in the serum of patients with SONFH than that of the normal subjects. The present study shows that the expression of C3, C4, ITIH4 and A2MG were significantly altered in patients with SONFH.	./cache/cord-339333-7tpnbr8q.txt	./txt/cord-339333-7tpnbr8q.txt