id	sid	tid	token	lemma	pos
cord-260708-l9w5jhsw	1	1	key	key	NN
cord-260708-l9w5jhsw	1	2	:	:	:
cord-260708-l9w5jhsw	1	3	cord-260708-l9w5jhsw	cord-260708-l9w5jhsw	NNP
cord-260708-l9w5jhsw	1	4	authors	author	NNS
cord-260708-l9w5jhsw	1	5	:	:	:
cord-260708-l9w5jhsw	1	6	Lasecka	Lasecka	NNP
cord-260708-l9w5jhsw	1	7	,	,	,
cord-260708-l9w5jhsw	1	8	Lidia	Lidia	NNP
cord-260708-l9w5jhsw	1	9	;	;	:
cord-260708-l9w5jhsw	1	10	Baron	Baron	NNP
cord-260708-l9w5jhsw	1	11	,	,	,
cord-260708-l9w5jhsw	1	12	Michael	Michael	NNP
cord-260708-l9w5jhsw	1	13	D.	D.	NNP
cord-260708-l9w5jhsw	1	14	title	title	NN
cord-260708-l9w5jhsw	1	15	:	:	:
cord-260708-l9w5jhsw	2	1	The	the	DT
cord-260708-l9w5jhsw	2	2	molecular	molecular	JJ
cord-260708-l9w5jhsw	2	3	biology	biology	NN
cord-260708-l9w5jhsw	2	4	of	of	IN
cord-260708-l9w5jhsw	2	5	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	2	6	,	,	,
cord-260708-l9w5jhsw	2	7	an	an	DT
cord-260708-l9w5jhsw	2	8	emerging	emerge	VBG
cord-260708-l9w5jhsw	2	9	group	group	NN
cord-260708-l9w5jhsw	2	10	of	of	IN
cord-260708-l9w5jhsw	2	11	tick	tick	NN
cord-260708-l9w5jhsw	2	12	-	-	HYPH
cord-260708-l9w5jhsw	2	13	borne	bear	VBN
cord-260708-l9w5jhsw	2	14	arboviruses	arbovirus	NNS
cord-260708-l9w5jhsw	2	15	date	date	NN
cord-260708-l9w5jhsw	2	16	:	:	:
cord-260708-l9w5jhsw	2	17	2013	2013	CD
cord-260708-l9w5jhsw	2	18	-	-	SYM
cord-260708-l9w5jhsw	2	19	12	12	CD
cord-260708-l9w5jhsw	2	20	-	-	SYM
cord-260708-l9w5jhsw	2	21	11	11	CD
cord-260708-l9w5jhsw	2	22	journal	journal	NN
cord-260708-l9w5jhsw	2	23	:	:	:
cord-260708-l9w5jhsw	3	1	Arch	Arch	NNP
cord-260708-l9w5jhsw	3	2	Virol	Virol	NNP
cord-260708-l9w5jhsw	4	1	DOI	DOI	NNP
cord-260708-l9w5jhsw	4	2	:	:	:
cord-260708-l9w5jhsw	5	1	10.1007	10.1007	CD
cord-260708-l9w5jhsw	5	2	/	/	SYM
cord-260708-l9w5jhsw	5	3	s00705	s00705	NNP
cord-260708-l9w5jhsw	5	4	-	-	HYPH
cord-260708-l9w5jhsw	5	5	013	013	CD
cord-260708-l9w5jhsw	5	6	-	-	HYPH
cord-260708-l9w5jhsw	5	7	1940-z	1940-z	NN
cord-260708-l9w5jhsw	5	8	sha	sha	NNP
cord-260708-l9w5jhsw	5	9	:	:	:
cord-260708-l9w5jhsw	6	1	395cb08e11b4d7c5b1e792099e059c6c8c96ae4a	395cb08e11b4d7c5b1e792099e059c6c8c96ae4a	NNP
cord-260708-l9w5jhsw	6	2	doc_id	doc_id	CD
cord-260708-l9w5jhsw	6	3	:	:	:
cord-260708-l9w5jhsw	6	4	260708	260708	CD
cord-260708-l9w5jhsw	6	5	cord_uid	cord_uid	NNS
cord-260708-l9w5jhsw	6	6	:	:	:
cord-260708-l9w5jhsw	7	1	l9w5jhsw	l9w5jhsw	VBZ
cord-260708-l9w5jhsw	7	2	The	the	DT
cord-260708-l9w5jhsw	7	3	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	7	4	are	be	VBP
cord-260708-l9w5jhsw	7	5	a	a	DT
cord-260708-l9w5jhsw	7	6	rapidly	rapidly	RB
cord-260708-l9w5jhsw	7	7	emerging	emerge	VBG
cord-260708-l9w5jhsw	7	8	group	group	NN
cord-260708-l9w5jhsw	7	9	of	of	IN
cord-260708-l9w5jhsw	7	10	tick	tick	NN
cord-260708-l9w5jhsw	7	11	-	-	HYPH
cord-260708-l9w5jhsw	7	12	borne	bear	VBN
cord-260708-l9w5jhsw	7	13	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	7	14	that	that	WDT
cord-260708-l9w5jhsw	7	15	includes	include	VBZ
cord-260708-l9w5jhsw	7	16	pathogens	pathogen	NNS
cord-260708-l9w5jhsw	7	17	of	of	IN
cord-260708-l9w5jhsw	7	18	humans	human	NNS
cord-260708-l9w5jhsw	7	19	(	(	-LRB-
cord-260708-l9w5jhsw	7	20	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	7	21	-	-	HYPH
cord-260708-l9w5jhsw	7	22	Congo	Congo	NNP
cord-260708-l9w5jhsw	7	23	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	7	24	fever	fever	NN
cord-260708-l9w5jhsw	7	25	virus	virus	NN
cord-260708-l9w5jhsw	7	26	[	[	-LRB-
cord-260708-l9w5jhsw	7	27	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	7	28	]	]	-RRB-
cord-260708-l9w5jhsw	7	29	)	)	-RRB-
cord-260708-l9w5jhsw	7	30	and	and	CC
cord-260708-l9w5jhsw	7	31	livestock	livestock	NN
cord-260708-l9w5jhsw	7	32	(	(	-LRB-
cord-260708-l9w5jhsw	7	33	Nairobi	Nairobi	NNP
cord-260708-l9w5jhsw	7	34	sheep	sheep	NN
cord-260708-l9w5jhsw	7	35	disease	disease	NN
cord-260708-l9w5jhsw	7	36	virus	virus	NN
cord-260708-l9w5jhsw	7	37	[	[	-LRB-
cord-260708-l9w5jhsw	7	38	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	7	39	]	]	-RRB-
cord-260708-l9w5jhsw	7	40	,	,	,
cord-260708-l9w5jhsw	7	41	also	also	RB
cord-260708-l9w5jhsw	7	42	known	know	VBN
cord-260708-l9w5jhsw	7	43	as	as	IN
cord-260708-l9w5jhsw	7	44	Ganjam	Ganjam	NNP
cord-260708-l9w5jhsw	7	45	virus	virus	NN
cord-260708-l9w5jhsw	7	46	)	)	-RRB-
cord-260708-l9w5jhsw	7	47	,	,	,
cord-260708-l9w5jhsw	7	48	as	as	RB
cord-260708-l9w5jhsw	7	49	well	well	RB
cord-260708-l9w5jhsw	7	50	as	as	IN
cord-260708-l9w5jhsw	7	51	a	a	DT
cord-260708-l9w5jhsw	7	52	large	large	JJ
cord-260708-l9w5jhsw	7	53	number	number	NN
cord-260708-l9w5jhsw	7	54	of	of	IN
cord-260708-l9w5jhsw	7	55	viruses	virus	NNS
cord-260708-l9w5jhsw	7	56	for	for	IN
cord-260708-l9w5jhsw	7	57	which	which	WDT
cord-260708-l9w5jhsw	7	58	the	the	DT
cord-260708-l9w5jhsw	7	59	normal	normal	JJ
cord-260708-l9w5jhsw	7	60	vertebrate	vertebrate	JJ
cord-260708-l9w5jhsw	7	61	host	host	NN
cord-260708-l9w5jhsw	7	62	has	have	VBZ
cord-260708-l9w5jhsw	7	63	not	not	RB
cord-260708-l9w5jhsw	7	64	been	be	VBN
cord-260708-l9w5jhsw	7	65	established	establish	VBN
cord-260708-l9w5jhsw	7	66	.	.	.
cord-260708-l9w5jhsw	8	1	Studies	study	NNS
cord-260708-l9w5jhsw	8	2	on	on	IN
cord-260708-l9w5jhsw	8	3	this	this	DT
cord-260708-l9w5jhsw	8	4	group	group	NN
cord-260708-l9w5jhsw	8	5	of	of	IN
cord-260708-l9w5jhsw	8	6	viruses	virus	NNS
cord-260708-l9w5jhsw	8	7	have	have	VBP
cord-260708-l9w5jhsw	8	8	been	be	VBN
cord-260708-l9w5jhsw	8	9	fairly	fairly	RB
cord-260708-l9w5jhsw	8	10	limited	limit	VBN
cord-260708-l9w5jhsw	8	11	,	,	,
cord-260708-l9w5jhsw	8	12	not	not	RB
cord-260708-l9w5jhsw	8	13	least	least	JJS
cord-260708-l9w5jhsw	8	14	because	because	IN
cord-260708-l9w5jhsw	8	15	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	8	16	is	be	VBZ
cord-260708-l9w5jhsw	8	17	a	a	DT
cord-260708-l9w5jhsw	8	18	BSL4	BSL4	NNP
cord-260708-l9w5jhsw	8	19	human	human	JJ
cord-260708-l9w5jhsw	8	20	pathogen	pathogen	NN
cord-260708-l9w5jhsw	8	21	,	,	,
cord-260708-l9w5jhsw	8	22	restricting	restrict	VBG
cord-260708-l9w5jhsw	8	23	the	the	DT
cord-260708-l9w5jhsw	8	24	number	number	NN
cord-260708-l9w5jhsw	8	25	of	of	IN
cord-260708-l9w5jhsw	8	26	labs	lab	NNS
cord-260708-l9w5jhsw	8	27	able	able	JJ
cord-260708-l9w5jhsw	8	28	to	to	TO
cord-260708-l9w5jhsw	8	29	study	study	VB
cord-260708-l9w5jhsw	8	30	the	the	DT
cord-260708-l9w5jhsw	8	31	live	live	JJ
cord-260708-l9w5jhsw	8	32	virus	virus	NN
cord-260708-l9w5jhsw	8	33	,	,	,
cord-260708-l9w5jhsw	8	34	while	while	IN
cord-260708-l9w5jhsw	8	35	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	8	36	,	,	,
cord-260708-l9w5jhsw	8	37	although	although	IN
cord-260708-l9w5jhsw	8	38	highly	highly	RB
cord-260708-l9w5jhsw	8	39	pathogenic	pathogenic	JJ
cord-260708-l9w5jhsw	8	40	in	in	IN
cord-260708-l9w5jhsw	8	41	naive	naive	JJ
cord-260708-l9w5jhsw	8	42	animals	animal	NNS
cord-260708-l9w5jhsw	8	43	,	,	,
cord-260708-l9w5jhsw	8	44	is	be	VBZ
cord-260708-l9w5jhsw	8	45	not	not	RB
cord-260708-l9w5jhsw	8	46	seen	see	VBN
cord-260708-l9w5jhsw	8	47	as	as	IN
cord-260708-l9w5jhsw	8	48	a	a	DT
cord-260708-l9w5jhsw	8	49	threat	threat	NN
cord-260708-l9w5jhsw	8	50	in	in	IN
cord-260708-l9w5jhsw	8	51	developed	develop	VBN
cord-260708-l9w5jhsw	8	52	countries	country	NNS
cord-260708-l9w5jhsw	8	53	,	,	,
cord-260708-l9w5jhsw	8	54	making	make	VBG
cord-260708-l9w5jhsw	8	55	it	-PRON-	PRP
cord-260708-l9w5jhsw	8	56	a	a	DT
cord-260708-l9w5jhsw	8	57	low	low	JJ
cord-260708-l9w5jhsw	8	58	priority	priority	NN
cord-260708-l9w5jhsw	8	59	.	.	.
cord-260708-l9w5jhsw	9	1	Nevertheless	nevertheless	RB
cord-260708-l9w5jhsw	9	2	,	,	,
cord-260708-l9w5jhsw	9	3	recent	recent	JJ
cord-260708-l9w5jhsw	9	4	years	year	NNS
cord-260708-l9w5jhsw	9	5	have	have	VBP
cord-260708-l9w5jhsw	9	6	seen	see	VBN
cord-260708-l9w5jhsw	9	7	significant	significant	JJ
cord-260708-l9w5jhsw	9	8	progress	progress	NN
cord-260708-l9w5jhsw	9	9	in	in	IN
cord-260708-l9w5jhsw	9	10	our	-PRON-	PRP$
cord-260708-l9w5jhsw	9	11	understanding	understanding	NN
cord-260708-l9w5jhsw	9	12	of	of	IN
cord-260708-l9w5jhsw	9	13	the	the	DT
cord-260708-l9w5jhsw	9	14	biology	biology	NN
cord-260708-l9w5jhsw	9	15	of	of	IN
cord-260708-l9w5jhsw	9	16	these	these	DT
cord-260708-l9w5jhsw	9	17	viruses	virus	NNS
cord-260708-l9w5jhsw	9	18	,	,	,
cord-260708-l9w5jhsw	9	19	particularly	particularly	RB
cord-260708-l9w5jhsw	9	20	that	that	IN
cord-260708-l9w5jhsw	9	21	of	of	IN
cord-260708-l9w5jhsw	9	22	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	9	23	,	,	,
cord-260708-l9w5jhsw	9	24	and	and	CC
cord-260708-l9w5jhsw	9	25	this	this	DT
cord-260708-l9w5jhsw	9	26	article	article	NN
cord-260708-l9w5jhsw	9	27	seeks	seek	VBZ
cord-260708-l9w5jhsw	9	28	to	to	TO
cord-260708-l9w5jhsw	9	29	draw	draw	VB
cord-260708-l9w5jhsw	9	30	together	together	RB
cord-260708-l9w5jhsw	9	31	our	-PRON-	PRP$
cord-260708-l9w5jhsw	9	32	existing	exist	VBG
cord-260708-l9w5jhsw	9	33	knowledge	knowledge	NN
cord-260708-l9w5jhsw	9	34	to	to	TO
cord-260708-l9w5jhsw	9	35	generate	generate	VB
cord-260708-l9w5jhsw	9	36	an	an	DT
cord-260708-l9w5jhsw	9	37	overall	overall	JJ
cord-260708-l9w5jhsw	9	38	picture	picture	NN
cord-260708-l9w5jhsw	9	39	of	of	IN
cord-260708-l9w5jhsw	9	40	their	-PRON-	PRP$
cord-260708-l9w5jhsw	9	41	molecular	molecular	JJ
cord-260708-l9w5jhsw	9	42	biology	biology	NN
cord-260708-l9w5jhsw	9	43	,	,	,
cord-260708-l9w5jhsw	9	44	underlining	underline	VBG
cord-260708-l9w5jhsw	9	45	areas	area	NNS
cord-260708-l9w5jhsw	9	46	of	of	IN
cord-260708-l9w5jhsw	9	47	particular	particular	JJ
cord-260708-l9w5jhsw	9	48	ignorance	ignorance	NN
cord-260708-l9w5jhsw	9	49	for	for	IN
cord-260708-l9w5jhsw	9	50	future	future	JJ
cord-260708-l9w5jhsw	9	51	studies	study	NNS
cord-260708-l9w5jhsw	9	52	.	.	.
cord-260708-l9w5jhsw	10	1	New	new	JJ
cord-260708-l9w5jhsw	10	2	viral	viral	JJ
cord-260708-l9w5jhsw	10	3	diseases	disease	NNS
cord-260708-l9w5jhsw	10	4	appear	appear	VBP
cord-260708-l9w5jhsw	10	5	with	with	IN
cord-260708-l9w5jhsw	10	6	increasing	increase	VBG
cord-260708-l9w5jhsw	10	7	frequency	frequency	NN
cord-260708-l9w5jhsw	10	8	.	.	.
cord-260708-l9w5jhsw	11	1	Just	just	RB
cord-260708-l9w5jhsw	11	2	in	in	IN
cord-260708-l9w5jhsw	11	3	the	the	DT
cord-260708-l9w5jhsw	11	4	last	last	JJ
cord-260708-l9w5jhsw	11	5	two	two	CD
cord-260708-l9w5jhsw	11	6	years	year	NNS
cord-260708-l9w5jhsw	11	7	we	-PRON-	PRP
cord-260708-l9w5jhsw	11	8	have	have	VBP
cord-260708-l9w5jhsw	11	9	seen	see	VBN
cord-260708-l9w5jhsw	11	10	the	the	DT
cord-260708-l9w5jhsw	11	11	appearance	appearance	NN
cord-260708-l9w5jhsw	11	12	of	of	IN
cord-260708-l9w5jhsw	11	13	a	a	DT
cord-260708-l9w5jhsw	11	14	new	new	JJ
cord-260708-l9w5jhsw	11	15	livestock	livestock	NN
cord-260708-l9w5jhsw	11	16	virus	virus	NN
cord-260708-l9w5jhsw	11	17	(	(	-LRB-
cord-260708-l9w5jhsw	11	18	Schmallenberg	Schmallenberg	NNP
cord-260708-l9w5jhsw	11	19	)	)	-RRB-
cord-260708-l9w5jhsw	11	20	and	and	CC
cord-260708-l9w5jhsw	11	21	a	a	DT
cord-260708-l9w5jhsw	11	22	new	new	JJ
cord-260708-l9w5jhsw	11	23	human	human	JJ
cord-260708-l9w5jhsw	11	24	pathogen	pathogen	NN
cord-260708-l9w5jhsw	11	25	(	(	-LRB-
cord-260708-l9w5jhsw	11	26	MERS	MERS	NNP
cord-260708-l9w5jhsw	11	27	coronavirus	coronavirus	NNP
cord-260708-l9w5jhsw	11	28	)	)	-RRB-
cord-260708-l9w5jhsw	11	29	.	.	.
cord-260708-l9w5jhsw	12	1	In	in	IN
cord-260708-l9w5jhsw	12	2	some	some	DT
cord-260708-l9w5jhsw	12	3	cases	case	NNS
cord-260708-l9w5jhsw	12	4	these	these	DT
cord-260708-l9w5jhsw	12	5	viruses	virus	NNS
cord-260708-l9w5jhsw	12	6	appear	appear	VBP
cord-260708-l9w5jhsw	12	7	to	to	TO
cord-260708-l9w5jhsw	12	8	be	be	VB
cord-260708-l9w5jhsw	12	9	completely	completely	RB
cord-260708-l9w5jhsw	12	10	new	new	JJ
cord-260708-l9w5jhsw	12	11	,	,	,
cord-260708-l9w5jhsw	12	12	in	in	IN
cord-260708-l9w5jhsw	12	13	others	other	NNS
cord-260708-l9w5jhsw	12	14	they	-PRON-	PRP
cord-260708-l9w5jhsw	12	15	have	have	VBP
cord-260708-l9w5jhsw	12	16	'	'	``
cord-260708-l9w5jhsw	12	17	emerged	emerge	VBN
cord-260708-l9w5jhsw	12	18	'	'	''
cord-260708-l9w5jhsw	12	19	into	into	IN
cord-260708-l9w5jhsw	12	20	our	-PRON-	PRP$
cord-260708-l9w5jhsw	12	21	awareness	awareness	NN
cord-260708-l9w5jhsw	12	22	as	as	IN
cord-260708-l9w5jhsw	12	23	human	human	JJ
cord-260708-l9w5jhsw	12	24	use	use	NN
cord-260708-l9w5jhsw	12	25	of	of	IN
cord-260708-l9w5jhsw	12	26	different	different	JJ
cord-260708-l9w5jhsw	12	27	habitats	habitat	NNS
cord-260708-l9w5jhsw	12	28	changes	change	NNS
cord-260708-l9w5jhsw	12	29	,	,	,
cord-260708-l9w5jhsw	12	30	leading	lead	VBG
cord-260708-l9w5jhsw	12	31	to	to	IN
cord-260708-l9w5jhsw	12	32	increased	increase	VBN
cord-260708-l9w5jhsw	12	33	contact	contact	NN
cord-260708-l9w5jhsw	12	34	with	with	IN
cord-260708-l9w5jhsw	12	35	carriers	carrier	NNS
cord-260708-l9w5jhsw	12	36	of	of	IN
cord-260708-l9w5jhsw	12	37	disease	disease	NN
cord-260708-l9w5jhsw	12	38	,	,	,
cord-260708-l9w5jhsw	12	39	whether	whether	IN
cord-260708-l9w5jhsw	12	40	those	those	DT
cord-260708-l9w5jhsw	12	41	carriers	carrier	NNS
cord-260708-l9w5jhsw	12	42	are	be	VBP
cord-260708-l9w5jhsw	12	43	'	'	``
cord-260708-l9w5jhsw	12	44	'	'	``
cord-260708-l9w5jhsw	12	45	bush	bush	NNP
cord-260708-l9w5jhsw	12	46	meat	meat	NNP
cord-260708-l9w5jhsw	12	47	'	'	''
cord-260708-l9w5jhsw	12	48	'	'	''
cord-260708-l9w5jhsw	12	49	or	or	CC
cord-260708-l9w5jhsw	12	50	the	the	DT
cord-260708-l9w5jhsw	12	51	many	many	JJ
cord-260708-l9w5jhsw	12	52	insect	insect	NN
cord-260708-l9w5jhsw	12	53	and	and	CC
cord-260708-l9w5jhsw	12	54	tick	tick	VB
cord-260708-l9w5jhsw	12	55	species	specie	NNS
cord-260708-l9w5jhsw	12	56	that	that	WDT
cord-260708-l9w5jhsw	12	57	can	can	MD
cord-260708-l9w5jhsw	12	58	act	act	VB
cord-260708-l9w5jhsw	12	59	as	as	IN
cord-260708-l9w5jhsw	12	60	vectors	vector	NNS
cord-260708-l9w5jhsw	12	61	of	of	IN
cord-260708-l9w5jhsw	12	62	disease	disease	NN
cord-260708-l9w5jhsw	12	63	.	.	.
cord-260708-l9w5jhsw	13	1	One	one	CD
cord-260708-l9w5jhsw	13	2	such	such	JJ
cord-260708-l9w5jhsw	13	3	group	group	NN
cord-260708-l9w5jhsw	13	4	of	of	IN
cord-260708-l9w5jhsw	13	5	viruses	virus	NNS
cord-260708-l9w5jhsw	13	6	that	that	WDT
cord-260708-l9w5jhsw	13	7	is	be	VBZ
cord-260708-l9w5jhsw	13	8	rapidly	rapidly	RB
cord-260708-l9w5jhsw	13	9	becoming	become	VBG
cord-260708-l9w5jhsw	13	10	more	more	RBR
cord-260708-l9w5jhsw	13	11	important	important	JJ
cord-260708-l9w5jhsw	13	12	is	be	VBZ
cord-260708-l9w5jhsw	13	13	the	the	DT
cord-260708-l9w5jhsw	13	14	genus	genus	NN
cord-260708-l9w5jhsw	13	15	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	13	16	in	in	IN
cord-260708-l9w5jhsw	13	17	the	the	DT
cord-260708-l9w5jhsw	13	18	family	family	NN
cord-260708-l9w5jhsw	13	19	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	13	20	.	.	.
cord-260708-l9w5jhsw	14	1	This	this	DT
cord-260708-l9w5jhsw	14	2	genus	genus	NN
cord-260708-l9w5jhsw	14	3	includes	include	VBZ
cord-260708-l9w5jhsw	14	4	a	a	DT
cord-260708-l9w5jhsw	14	5	number	number	NN
cord-260708-l9w5jhsw	14	6	of	of	IN
cord-260708-l9w5jhsw	14	7	human	human	NN
cord-260708-l9w5jhsw	14	8	and	and	CC
cord-260708-l9w5jhsw	14	9	livestock	livestock	NN
cord-260708-l9w5jhsw	14	10	pathogens	pathogen	NNS
cord-260708-l9w5jhsw	14	11	,	,	,
cord-260708-l9w5jhsw	14	12	as	as	RB
cord-260708-l9w5jhsw	14	13	well	well	RB
cord-260708-l9w5jhsw	14	14	as	as	IN
cord-260708-l9w5jhsw	14	15	a	a	DT
cord-260708-l9w5jhsw	14	16	collection	collection	NN
cord-260708-l9w5jhsw	14	17	of	of	IN
cord-260708-l9w5jhsw	14	18	other	other	JJ
cord-260708-l9w5jhsw	14	19	viruses	virus	NNS
cord-260708-l9w5jhsw	14	20	about	about	IN
cord-260708-l9w5jhsw	14	21	which	which	WDT
cord-260708-l9w5jhsw	14	22	little	little	JJ
cord-260708-l9w5jhsw	14	23	is	be	VBZ
cord-260708-l9w5jhsw	14	24	known	know	VBN
cord-260708-l9w5jhsw	14	25	,	,	,
cord-260708-l9w5jhsw	14	26	not	not	RB
cord-260708-l9w5jhsw	14	27	even	even	RB
cord-260708-l9w5jhsw	14	28	the	the	DT
cord-260708-l9w5jhsw	14	29	host	host	NN
cord-260708-l9w5jhsw	14	30	in	in	IN
cord-260708-l9w5jhsw	14	31	which	which	WDT
cord-260708-l9w5jhsw	14	32	they	-PRON-	PRP
cord-260708-l9w5jhsw	14	33	naturally	naturally	RB
cord-260708-l9w5jhsw	14	34	circulate	circulate	VBP
cord-260708-l9w5jhsw	14	35	.	.	.
cord-260708-l9w5jhsw	15	1	The	the	DT
cord-260708-l9w5jhsw	15	2	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	15	3	show	show	VBP
cord-260708-l9w5jhsw	15	4	a	a	DT
cord-260708-l9w5jhsw	15	5	number	number	NN
cord-260708-l9w5jhsw	15	6	of	of	IN
cord-260708-l9w5jhsw	15	7	unique	unique	JJ
cord-260708-l9w5jhsw	15	8	features	feature	NNS
cord-260708-l9w5jhsw	15	9	,	,	,
cord-260708-l9w5jhsw	15	10	and	and	CC
cord-260708-l9w5jhsw	15	11	the	the	DT
cord-260708-l9w5jhsw	15	12	purpose	purpose	NN
cord-260708-l9w5jhsw	15	13	of	of	IN
cord-260708-l9w5jhsw	15	14	this	this	DT
cord-260708-l9w5jhsw	15	15	article	article	NN
cord-260708-l9w5jhsw	15	16	is	be	VBZ
cord-260708-l9w5jhsw	15	17	to	to	TO
cord-260708-l9w5jhsw	15	18	summarise	summarise	VB
cord-260708-l9w5jhsw	15	19	our	-PRON-	PRP$
cord-260708-l9w5jhsw	15	20	current	current	JJ
cord-260708-l9w5jhsw	15	21	knowledge	knowledge	NN
cord-260708-l9w5jhsw	15	22	of	of	IN
cord-260708-l9w5jhsw	15	23	the	the	DT
cord-260708-l9w5jhsw	15	24	molecular	molecular	JJ
cord-260708-l9w5jhsw	15	25	biology	biology	NN
cord-260708-l9w5jhsw	15	26	of	of	IN
cord-260708-l9w5jhsw	15	27	these	these	DT
cord-260708-l9w5jhsw	15	28	viruses	virus	NNS
cord-260708-l9w5jhsw	15	29	and	and	CC
cord-260708-l9w5jhsw	15	30	highlight	highlight	NN
cord-260708-l9w5jhsw	15	31	areas	area	NNS
cord-260708-l9w5jhsw	15	32	where	where	WRB
cord-260708-l9w5jhsw	15	33	it	-PRON-	PRP
cord-260708-l9w5jhsw	15	34	is	be	VBZ
cord-260708-l9w5jhsw	15	35	to	to	TO
cord-260708-l9w5jhsw	15	36	be	be	VB
cord-260708-l9w5jhsw	15	37	expected	expect	VBN
cord-260708-l9w5jhsw	15	38	that	that	DT
cord-260708-l9w5jhsw	15	39	research	research	NN
cord-260708-l9w5jhsw	15	40	will	will	MD
cord-260708-l9w5jhsw	15	41	soon	soon	RB
cord-260708-l9w5jhsw	15	42	bear	bear	VB
cord-260708-l9w5jhsw	15	43	fruit	fruit	NN
cord-260708-l9w5jhsw	15	44	.	.	.
cord-260708-l9w5jhsw	16	1	A	a	DT
cord-260708-l9w5jhsw	16	2	primary	primary	JJ
cord-260708-l9w5jhsw	16	3	characteristic	characteristic	NN
cord-260708-l9w5jhsw	16	4	of	of	IN
cord-260708-l9w5jhsw	16	5	the	the	DT
cord-260708-l9w5jhsw	16	6	viruses	virus	NNS
cord-260708-l9w5jhsw	16	7	of	of	IN
cord-260708-l9w5jhsw	16	8	the	the	DT
cord-260708-l9w5jhsw	16	9	genus	genus	NN
cord-260708-l9w5jhsw	16	10	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	16	11	,	,	,
cord-260708-l9w5jhsw	16	12	distinguishing	distinguish	VBG
cord-260708-l9w5jhsw	16	13	them	-PRON-	PRP
cord-260708-l9w5jhsw	16	14	from	from	IN
cord-260708-l9w5jhsw	16	15	most	most	JJS
cord-260708-l9w5jhsw	16	16	of	of	IN
cord-260708-l9w5jhsw	16	17	the	the	DT
cord-260708-l9w5jhsw	16	18	other	other	JJ
cord-260708-l9w5jhsw	16	19	members	member	NNS
cord-260708-l9w5jhsw	16	20	of	of	IN
cord-260708-l9w5jhsw	16	21	the	the	DT
cord-260708-l9w5jhsw	16	22	family	family	NN
cord-260708-l9w5jhsw	16	23	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	16	24	,	,	,
cord-260708-l9w5jhsw	16	25	is	be	VBZ
cord-260708-l9w5jhsw	16	26	that	that	IN
cord-260708-l9w5jhsw	16	27	they	-PRON-	PRP
cord-260708-l9w5jhsw	16	28	are	be	VBP
cord-260708-l9w5jhsw	16	29	all	all	RB
cord-260708-l9w5jhsw	16	30	transmitted	transmit	VBN
cord-260708-l9w5jhsw	16	31	by	by	IN
cord-260708-l9w5jhsw	16	32	ticks	tick	NNS
cord-260708-l9w5jhsw	16	33	[	[	-LRB-
cord-260708-l9w5jhsw	16	34	109	109	CD
cord-260708-l9w5jhsw	16	35	]	]	-RRB-
cord-260708-l9w5jhsw	16	36	.	.	.
cord-260708-l9w5jhsw	17	1	Based	base	VBN
cord-260708-l9w5jhsw	17	2	on	on	IN
cord-260708-l9w5jhsw	17	3	antibody	antibody	NN
cord-260708-l9w5jhsw	17	4	cross	cross	NN
cord-260708-l9w5jhsw	17	5	-	-	NN
cord-260708-l9w5jhsw	17	6	reactivity	reactivity	NN
cord-260708-l9w5jhsw	17	7	,	,	,
cord-260708-l9w5jhsw	17	8	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	17	9	are	be	VBP
cord-260708-l9w5jhsw	17	10	classified	classify	VBN
cord-260708-l9w5jhsw	17	11	into	into	IN
cord-260708-l9w5jhsw	17	12	seven	seven	CD
cord-260708-l9w5jhsw	17	13	serogroups	serogroup	NNS
cord-260708-l9w5jhsw	17	14	(	(	-LRB-
cord-260708-l9w5jhsw	17	15	Table	table	NN
cord-260708-l9w5jhsw	17	16	1	1	CD
cord-260708-l9w5jhsw	17	17	)	)	-RRB-
cord-260708-l9w5jhsw	17	18	[	[	-LRB-
cord-260708-l9w5jhsw	17	19	32	32	CD
cord-260708-l9w5jhsw	17	20	,	,	,
cord-260708-l9w5jhsw	17	21	39	39	CD
cord-260708-l9w5jhsw	17	22	,	,	,
cord-260708-l9w5jhsw	17	23	190	190	CD
cord-260708-l9w5jhsw	17	24	]	]	-RRB-
cord-260708-l9w5jhsw	17	25	,	,	,
cord-260708-l9w5jhsw	17	26	of	of	IN
cord-260708-l9w5jhsw	17	27	which	which	WDT
cord-260708-l9w5jhsw	17	28	the	the	DT
cord-260708-l9w5jhsw	17	29	most	most	RBS
cord-260708-l9w5jhsw	17	30	important	important	JJ
cord-260708-l9w5jhsw	17	31	are	be	VBP
cord-260708-l9w5jhsw	17	32	the	the	DT
cord-260708-l9w5jhsw	17	33	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	17	34	-	-	HYPH
cord-260708-l9w5jhsw	17	35	Congo	Congo	NNP
cord-260708-l9w5jhsw	17	36	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	17	37	fever	fever	NN
cord-260708-l9w5jhsw	17	38	(	(	-LRB-
cord-260708-l9w5jhsw	17	39	CCHF	CCHF	NNP
cord-260708-l9w5jhsw	17	40	)	)	-RRB-
cord-260708-l9w5jhsw	17	41	group	group	NN
cord-260708-l9w5jhsw	17	42	,	,	,
cord-260708-l9w5jhsw	17	43	which	which	WDT
cord-260708-l9w5jhsw	17	44	includes	include	VBZ
cord-260708-l9w5jhsw	17	45	the	the	DT
cord-260708-l9w5jhsw	17	46	human	human	JJ
cord-260708-l9w5jhsw	17	47	pathogen	pathogen	NN
cord-260708-l9w5jhsw	17	48	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	17	49	-	-	HYPH
cord-260708-l9w5jhsw	17	50	Congo	Congo	NNP
cord-260708-l9w5jhsw	17	51	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	17	52	fever	fever	NN
cord-260708-l9w5jhsw	17	53	virus	virus	NN
cord-260708-l9w5jhsw	17	54	(	(	-LRB-
cord-260708-l9w5jhsw	17	55	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	17	56	)	)	-RRB-
cord-260708-l9w5jhsw	17	57	,	,	,
cord-260708-l9w5jhsw	17	58	and	and	CC
cord-260708-l9w5jhsw	17	59	the	the	DT
cord-260708-l9w5jhsw	17	60	Nairobi	Nairobi	NNP
cord-260708-l9w5jhsw	17	61	sheep	sheep	NN
cord-260708-l9w5jhsw	17	62	disease	disease	NN
cord-260708-l9w5jhsw	17	63	(	(	-LRB-
cord-260708-l9w5jhsw	17	64	NSD	NSD	NNP
cord-260708-l9w5jhsw	17	65	)	)	-RRB-
cord-260708-l9w5jhsw	17	66	group	group	NN
cord-260708-l9w5jhsw	17	67	,	,	,
cord-260708-l9w5jhsw	17	68	to	to	TO
cord-260708-l9w5jhsw	17	69	which	which	WDT
cord-260708-l9w5jhsw	17	70	belong	belong	VBP
cord-260708-l9w5jhsw	17	71	Nairobi	Nairobi	NNP
cord-260708-l9w5jhsw	17	72	sheep	sheep	NN
cord-260708-l9w5jhsw	17	73	disease	disease	NN
cord-260708-l9w5jhsw	17	74	virus	virus	NN
cord-260708-l9w5jhsw	17	75	(	(	-LRB-
cord-260708-l9w5jhsw	17	76	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	17	77	)	)	-RRB-
cord-260708-l9w5jhsw	18	1	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	18	2	virus	virus	NN
cord-260708-l9w5jhsw	18	3	(	(	-LRB-
cord-260708-l9w5jhsw	18	4	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	18	5	)	)	-RRB-
cord-260708-l9w5jhsw	18	6	and	and	CC
cord-260708-l9w5jhsw	18	7	Kupe	Kupe	NNP
cord-260708-l9w5jhsw	18	8	virus	virus	NN
cord-260708-l9w5jhsw	18	9	(	(	-LRB-
cord-260708-l9w5jhsw	18	10	KUPV	KUPV	NNP
cord-260708-l9w5jhsw	18	11	)	)	-RRB-
cord-260708-l9w5jhsw	18	12	.	.	.
cord-260708-l9w5jhsw	19	1	KUPV	KUPV	NNP
cord-260708-l9w5jhsw	19	2	[	[	-LRB-
cord-260708-l9w5jhsw	19	3	43	43	CD
cord-260708-l9w5jhsw	19	4	]	]	-RRB-
cord-260708-l9w5jhsw	19	5	and	and	CC
cord-260708-l9w5jhsw	19	6	Finch	Finch	NNP
cord-260708-l9w5jhsw	19	7	Creek	Creek	NNP
cord-260708-l9w5jhsw	19	8	virus	virus	NN
cord-260708-l9w5jhsw	19	9	[	[	-LRB-
cord-260708-l9w5jhsw	19	10	102	102	CD
cord-260708-l9w5jhsw	19	11	]	]	-RRB-
cord-260708-l9w5jhsw	20	1	are	be	VBP
cord-260708-l9w5jhsw	20	2	the	the	DT
cord-260708-l9w5jhsw	20	3	most	most	RBS
cord-260708-l9w5jhsw	20	4	recently	recently	RB
cord-260708-l9w5jhsw	20	5	discovered	discover	VBN
cord-260708-l9w5jhsw	20	6	viruses	virus	NNS
cord-260708-l9w5jhsw	20	7	of	of	IN
cord-260708-l9w5jhsw	20	8	this	this	DT
cord-260708-l9w5jhsw	20	9	genus	genus	NN
cord-260708-l9w5jhsw	20	10	.	.	.
cord-260708-l9w5jhsw	21	1	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	21	2	is	be	VBZ
cord-260708-l9w5jhsw	21	3	arguably	arguably	RB
cord-260708-l9w5jhsw	21	4	the	the	DT
cord-260708-l9w5jhsw	21	5	most	most	RBS
cord-260708-l9w5jhsw	21	6	important	important	JJ
cord-260708-l9w5jhsw	21	7	from	from	IN
cord-260708-l9w5jhsw	21	8	a	a	DT
cord-260708-l9w5jhsw	21	9	human	human	JJ
cord-260708-l9w5jhsw	21	10	perspective	perspective	NN
cord-260708-l9w5jhsw	21	11	,	,	,
cord-260708-l9w5jhsw	21	12	causing	cause	VBG
cord-260708-l9w5jhsw	21	13	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	21	14	fever	fever	NN
cord-260708-l9w5jhsw	21	15	in	in	IN
cord-260708-l9w5jhsw	21	16	humans	human	NNS
cord-260708-l9w5jhsw	21	17	,	,	,
cord-260708-l9w5jhsw	21	18	with	with	IN
cord-260708-l9w5jhsw	21	19	mortality	mortality	NN
cord-260708-l9w5jhsw	21	20	up	up	IN
cord-260708-l9w5jhsw	21	21	to	to	TO
cord-260708-l9w5jhsw	21	22	30	30	CD
cord-260708-l9w5jhsw	21	23	%	%	NN
cord-260708-l9w5jhsw	21	24	(	(	-LRB-
cord-260708-l9w5jhsw	21	25	reviewed	review	VBN
cord-260708-l9w5jhsw	21	26	in	in	IN
cord-260708-l9w5jhsw	21	27	refs	ref	NNS
cord-260708-l9w5jhsw	21	28	.	.	.
cord-260708-l9w5jhsw	22	1	[	[	-LRB-
cord-260708-l9w5jhsw	22	2	58	58	CD
cord-260708-l9w5jhsw	22	3	]	]	-RRB-
cord-260708-l9w5jhsw	22	4	and	and	CC
cord-260708-l9w5jhsw	22	5	[	[	-LRB-
cord-260708-l9w5jhsw	22	6	182	182	CD
cord-260708-l9w5jhsw	22	7	]	]	-RRB-
cord-260708-l9w5jhsw	22	8	)	)	-RRB-
cord-260708-l9w5jhsw	22	9	.	.	.
cord-260708-l9w5jhsw	23	1	After	after	IN
cord-260708-l9w5jhsw	23	2	dengue	dengue	NN
cord-260708-l9w5jhsw	23	3	virus	virus	NN
cord-260708-l9w5jhsw	23	4	,	,	,
cord-260708-l9w5jhsw	23	5	this	this	DT
cord-260708-l9w5jhsw	23	6	is	be	VBZ
cord-260708-l9w5jhsw	23	7	the	the	DT
cord-260708-l9w5jhsw	23	8	second	second	JJ
cord-260708-l9w5jhsw	23	9	most	most	RBS
cord-260708-l9w5jhsw	23	10	widespread	widespread	JJ
cord-260708-l9w5jhsw	23	11	of	of	IN
cord-260708-l9w5jhsw	23	12	the	the	DT
cord-260708-l9w5jhsw	23	13	arboviruses	arbovirus	NNS
cord-260708-l9w5jhsw	23	14	that	that	WDT
cord-260708-l9w5jhsw	23	15	are	be	VBP
cord-260708-l9w5jhsw	23	16	pathogenic	pathogenic	JJ
cord-260708-l9w5jhsw	23	17	to	to	IN
cord-260708-l9w5jhsw	23	18	humans	human	NNS
cord-260708-l9w5jhsw	23	19	;	;	:
cord-260708-l9w5jhsw	23	20	cases	case	NNS
cord-260708-l9w5jhsw	23	21	of	of	IN
cord-260708-l9w5jhsw	23	22	CCHF	CCHF	NNP
cord-260708-l9w5jhsw	23	23	have	have	VBP
cord-260708-l9w5jhsw	23	24	been	be	VBN
cord-260708-l9w5jhsw	23	25	reported	report	VBN
cord-260708-l9w5jhsw	23	26	in	in	IN
cord-260708-l9w5jhsw	23	27	sub	sub	JJ
cord-260708-l9w5jhsw	23	28	-	-	JJ
cord-260708-l9w5jhsw	23	29	Saharan	Saharan	NNP
cord-260708-l9w5jhsw	23	30	Africa	Africa	NNP
cord-260708-l9w5jhsw	23	31	,	,	,
cord-260708-l9w5jhsw	23	32	the	the	DT
cord-260708-l9w5jhsw	23	33	former	former	JJ
cord-260708-l9w5jhsw	23	34	Soviet	Soviet	NNP
cord-260708-l9w5jhsw	23	35	Union	Union	NNP
cord-260708-l9w5jhsw	23	36	,	,	,
cord-260708-l9w5jhsw	23	37	Bulgaria	Bulgaria	NNP
cord-260708-l9w5jhsw	23	38	,	,	,
cord-260708-l9w5jhsw	23	39	Turkey	Turkey	NNP
cord-260708-l9w5jhsw	23	40	,	,	,
cord-260708-l9w5jhsw	23	41	China	China	NNP
cord-260708-l9w5jhsw	23	42	,	,	,
cord-260708-l9w5jhsw	23	43	Pakistan	Pakistan	NNP
cord-260708-l9w5jhsw	23	44	,	,	,
cord-260708-l9w5jhsw	23	45	India	India	NNP
cord-260708-l9w5jhsw	23	46	,	,	,
cord-260708-l9w5jhsw	23	47	the	the	DT
cord-260708-l9w5jhsw	23	48	Arabian	Arabian	NNP
cord-260708-l9w5jhsw	23	49	Peninsula	Peninsula	NNP
cord-260708-l9w5jhsw	23	50	,	,	,
cord-260708-l9w5jhsw	23	51	northern	northern	JJ
cord-260708-l9w5jhsw	23	52	Greece	Greece	NNP
cord-260708-l9w5jhsw	23	53	,	,	,
cord-260708-l9w5jhsw	23	54	Iraq	Iraq	NNP
cord-260708-l9w5jhsw	23	55	and	and	CC
cord-260708-l9w5jhsw	23	56	Iran	Iran	NNP
cord-260708-l9w5jhsw	23	57	[	[	-LRB-
cord-260708-l9w5jhsw	23	58	26	26	CD
cord-260708-l9w5jhsw	23	59	,	,	,
cord-260708-l9w5jhsw	23	60	53	53	CD
cord-260708-l9w5jhsw	23	61	-	-	SYM
cord-260708-l9w5jhsw	23	62	55	55	CD
cord-260708-l9w5jhsw	23	63	,	,	,
cord-260708-l9w5jhsw	23	64	115	115	CD
cord-260708-l9w5jhsw	23	65	,	,	,
cord-260708-l9w5jhsw	23	66	121	121	CD
cord-260708-l9w5jhsw	23	67	-	-	SYM
cord-260708-l9w5jhsw	23	68	123	123	CD
cord-260708-l9w5jhsw	23	69	,	,	,
cord-260708-l9w5jhsw	23	70	183	183	CD
cord-260708-l9w5jhsw	23	71	]	]	-RRB-
cord-260708-l9w5jhsw	23	72	.	.	.
cord-260708-l9w5jhsw	24	1	Although	although	IN
cord-260708-l9w5jhsw	24	2	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	24	3	can	can	MD
cord-260708-l9w5jhsw	24	4	infect	infect	VB
cord-260708-l9w5jhsw	24	5	several	several	JJ
cord-260708-l9w5jhsw	24	6	mammalian	mammalian	JJ
cord-260708-l9w5jhsw	24	7	species	specie	NNS
cord-260708-l9w5jhsw	24	8	,	,	,
cord-260708-l9w5jhsw	24	9	it	-PRON-	PRP
cord-260708-l9w5jhsw	24	10	appears	appear	VBZ
cord-260708-l9w5jhsw	24	11	to	to	TO
cord-260708-l9w5jhsw	24	12	cause	cause	VB
cord-260708-l9w5jhsw	24	13	disease	disease	NN
cord-260708-l9w5jhsw	24	14	only	only	RB
cord-260708-l9w5jhsw	24	15	in	in	IN
cord-260708-l9w5jhsw	24	16	man	man	NN
cord-260708-l9w5jhsw	24	17	[	[	-LRB-
cord-260708-l9w5jhsw	24	18	124	124	CD
cord-260708-l9w5jhsw	24	19	,	,	,
cord-260708-l9w5jhsw	24	20	158	158	CD
cord-260708-l9w5jhsw	24	21	]	]	-RRB-
cord-260708-l9w5jhsw	24	22	.	.	.
cord-260708-l9w5jhsw	25	1	Because	because	IN
cord-260708-l9w5jhsw	25	2	of	of	IN
cord-260708-l9w5jhsw	25	3	its	-PRON-	PRP$
cord-260708-l9w5jhsw	25	4	importance	importance	NN
cord-260708-l9w5jhsw	25	5	as	as	IN
cord-260708-l9w5jhsw	25	6	a	a	DT
cord-260708-l9w5jhsw	25	7	human	human	JJ
cord-260708-l9w5jhsw	25	8	pathogen	pathogen	NN
cord-260708-l9w5jhsw	25	9	,	,	,
cord-260708-l9w5jhsw	25	10	most	most	JJS
cord-260708-l9w5jhsw	25	11	of	of	IN
cord-260708-l9w5jhsw	25	12	the	the	DT
cord-260708-l9w5jhsw	25	13	available	available	JJ
cord-260708-l9w5jhsw	25	14	data	datum	NNS
cord-260708-l9w5jhsw	25	15	on	on	IN
cord-260708-l9w5jhsw	25	16	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	25	17	come	come	VBP
cord-260708-l9w5jhsw	25	18	from	from	IN
cord-260708-l9w5jhsw	25	19	studies	study	NNS
cord-260708-l9w5jhsw	25	20	on	on	IN
cord-260708-l9w5jhsw	25	21	this	this	DT
cord-260708-l9w5jhsw	25	22	virus	virus	NN
cord-260708-l9w5jhsw	25	23	,	,	,
cord-260708-l9w5jhsw	25	24	though	though	IN
cord-260708-l9w5jhsw	25	25	studies	study	NNS
cord-260708-l9w5jhsw	25	26	on	on	IN
cord-260708-l9w5jhsw	25	27	other	other	JJ
cord-260708-l9w5jhsw	25	28	members	member	NNS
cord-260708-l9w5jhsw	25	29	of	of	IN
cord-260708-l9w5jhsw	25	30	the	the	DT
cord-260708-l9w5jhsw	25	31	group	group	NN
cord-260708-l9w5jhsw	25	32	have	have	VBP
cord-260708-l9w5jhsw	25	33	also	also	RB
cord-260708-l9w5jhsw	25	34	contributed	contribute	VBN
cord-260708-l9w5jhsw	25	35	,	,	,
cord-260708-l9w5jhsw	25	36	notably	notably	RB
cord-260708-l9w5jhsw	25	37	on	on	IN
cord-260708-l9w5jhsw	25	38	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	25	39	,	,	,
cord-260708-l9w5jhsw	25	40	a	a	DT
cord-260708-l9w5jhsw	25	41	virus	virus	NN
cord-260708-l9w5jhsw	25	42	first	first	RB
cord-260708-l9w5jhsw	25	43	identified	identify	VBD
cord-260708-l9w5jhsw	25	44	nearly	nearly	RB
cord-260708-l9w5jhsw	25	45	a	a	DT
cord-260708-l9w5jhsw	25	46	hundred	hundred	CD
cord-260708-l9w5jhsw	25	47	years	year	NNS
cord-260708-l9w5jhsw	25	48	ago	ago	RB
cord-260708-l9w5jhsw	25	49	as	as	IN
cord-260708-l9w5jhsw	25	50	a	a	DT
cord-260708-l9w5jhsw	25	51	tick	tick	VB
cord-260708-l9w5jhsw	25	52	-	-	HYPH
cord-260708-l9w5jhsw	25	53	borne	bear	VBN
cord-260708-l9w5jhsw	25	54	virus	virus	NN
cord-260708-l9w5jhsw	25	55	that	that	WDT
cord-260708-l9w5jhsw	25	56	causes	cause	VBZ
cord-260708-l9w5jhsw	25	57	severe	severe	JJ
cord-260708-l9w5jhsw	25	58	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	25	59	gastroenteritis	gastroenteritis	NN
cord-260708-l9w5jhsw	25	60	in	in	IN
cord-260708-l9w5jhsw	25	61	sheep	sheep	NN
cord-260708-l9w5jhsw	25	62	and	and	CC
cord-260708-l9w5jhsw	25	63	goats	goat	NNS
cord-260708-l9w5jhsw	25	64	,	,	,
cord-260708-l9w5jhsw	25	65	with	with	IN
cord-260708-l9w5jhsw	25	66	mortality	mortality	NN
cord-260708-l9w5jhsw	25	67	rates	rate	NNS
cord-260708-l9w5jhsw	25	68	of	of	IN
cord-260708-l9w5jhsw	25	69	up	up	IN
cord-260708-l9w5jhsw	25	70	to	to	TO
cord-260708-l9w5jhsw	25	71	90	90	CD
cord-260708-l9w5jhsw	25	72	%	%	NN
cord-260708-l9w5jhsw	25	73	in	in	IN
cord-260708-l9w5jhsw	25	74	susceptible	susceptible	JJ
cord-260708-l9w5jhsw	25	75	populations	population	NNS
cord-260708-l9w5jhsw	25	76	[	[	-LRB-
cord-260708-l9w5jhsw	25	77	113	113	CD
cord-260708-l9w5jhsw	25	78	,	,	,
cord-260708-l9w5jhsw	25	79	167	167	CD
cord-260708-l9w5jhsw	25	80	,	,	,
cord-260708-l9w5jhsw	25	81	181	181	CD
cord-260708-l9w5jhsw	25	82	]	]	-RRB-
cord-260708-l9w5jhsw	25	83	.	.	.
cord-260708-l9w5jhsw	26	1	Interestingly	interestingly	RB
cord-260708-l9w5jhsw	26	2	,	,	,
cord-260708-l9w5jhsw	26	3	an	an	DT
cord-260708-l9w5jhsw	26	4	Asian	asian	JJ
cord-260708-l9w5jhsw	26	5	virus	virus	NN
cord-260708-l9w5jhsw	26	6	causing	cause	VBG
cord-260708-l9w5jhsw	26	7	a	a	DT
cord-260708-l9w5jhsw	26	8	similar	similar	JJ
cord-260708-l9w5jhsw	26	9	disease	disease	NN
cord-260708-l9w5jhsw	26	10	,	,	,
cord-260708-l9w5jhsw	26	11	Ganjam	Ganjam	NNP
cord-260708-l9w5jhsw	26	12	virus	virus	NN
cord-260708-l9w5jhsw	26	13	(	(	-LRB-
cord-260708-l9w5jhsw	26	14	GV	GV	NNP
cord-260708-l9w5jhsw	26	15	)	)	-RRB-
cord-260708-l9w5jhsw	26	16	,	,	,
cord-260708-l9w5jhsw	26	17	was	be	VBD
cord-260708-l9w5jhsw	26	18	recently	recently	RB
cord-260708-l9w5jhsw	26	19	identified	identify	VBN
cord-260708-l9w5jhsw	26	20	,	,	,
cord-260708-l9w5jhsw	26	21	based	base	VBN
cord-260708-l9w5jhsw	26	22	on	on	IN
cord-260708-l9w5jhsw	26	23	genetic	genetic	JJ
cord-260708-l9w5jhsw	26	24	and	and	CC
cord-260708-l9w5jhsw	26	25	serological	serological	JJ
cord-260708-l9w5jhsw	26	26	studies	study	NNS
cord-260708-l9w5jhsw	26	27	,	,	,
cord-260708-l9w5jhsw	26	28	as	as	IN
cord-260708-l9w5jhsw	26	29	being	be	VBG
cord-260708-l9w5jhsw	26	30	the	the	DT
cord-260708-l9w5jhsw	26	31	same	same	JJ
cord-260708-l9w5jhsw	26	32	virus	virus	NN
cord-260708-l9w5jhsw	26	33	as	as	IN
cord-260708-l9w5jhsw	26	34	that	that	DT
cord-260708-l9w5jhsw	26	35	causing	cause	VBG
cord-260708-l9w5jhsw	26	36	NSD	NSD	NNP
cord-260708-l9w5jhsw	26	37	in	in	IN
cord-260708-l9w5jhsw	26	38	East	East	NNP
cord-260708-l9w5jhsw	26	39	Haemorrhagic	Haemorrhagic	NNP
cord-260708-l9w5jhsw	26	40	gastroenteritis	gastroenteritis	NN
cord-260708-l9w5jhsw	26	41	in	in	IN
cord-260708-l9w5jhsw	26	42	sheep	sheep	NN
cord-260708-l9w5jhsw	26	43	and	and	CC
cord-260708-l9w5jhsw	26	44	goats	goat	NNS
cord-260708-l9w5jhsw	26	45	[	[	-LRB-
cord-260708-l9w5jhsw	26	46	106	106	CD
cord-260708-l9w5jhsw	26	47	,	,	,
cord-260708-l9w5jhsw	26	48	113	113	CD
cord-260708-l9w5jhsw	26	49	]	]	-RRB-
cord-260708-l9w5jhsw	26	50	.	.	.
cord-260708-l9w5jhsw	27	1	Antibodies	antibody	NNS
cord-260708-l9w5jhsw	27	2	to	to	IN
cord-260708-l9w5jhsw	27	3	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	27	4	/	/	SYM
cord-260708-l9w5jhsw	27	5	GV	GV	NNP
cord-260708-l9w5jhsw	27	6	have	have	VBP
cord-260708-l9w5jhsw	27	7	been	be	VBN
cord-260708-l9w5jhsw	27	8	reported	report	VBN
cord-260708-l9w5jhsw	27	9	in	in	IN
cord-260708-l9w5jhsw	27	10	humans	human	NNS
cord-260708-l9w5jhsw	27	11	,	,	,
cord-260708-l9w5jhsw	27	12	but	but	CC
cord-260708-l9w5jhsw	27	13	otherwise	otherwise	RB
cord-260708-l9w5jhsw	27	14	only	only	RB
cord-260708-l9w5jhsw	27	15	laboratoryacquired	laboratoryacquired	JJ
cord-260708-l9w5jhsw	27	16	infections	infection	NNS
cord-260708-l9w5jhsw	27	17	have	have	VBP
cord-260708-l9w5jhsw	27	18	been	be	VBN
cord-260708-l9w5jhsw	27	19	seen	see	VBN
cord-260708-l9w5jhsw	27	20	[	[	-LRB-
cord-260708-l9w5jhsw	27	21	13	13	CD
cord-260708-l9w5jhsw	27	22	,	,	,
cord-260708-l9w5jhsw	27	23	45	45	CD
cord-260708-l9w5jhsw	27	24	,	,	,
cord-260708-l9w5jhsw	27	25	133	133	CD
cord-260708-l9w5jhsw	27	26	]	]	-RRB-
cord-260708-l9w5jhsw	27	27	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	27	28	virus	virus	NN
cord-260708-l9w5jhsw	27	29	(	(	-LRB-
cord-260708-l9w5jhsw	27	30	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	27	31	)	)	-RRB-
cord-260708-l9w5jhsw	27	32	Frequently	frequently	RB
cord-260708-l9w5jhsw	27	33	isolated	isolate	VBN
cord-260708-l9w5jhsw	27	34	from	from	IN
cord-260708-l9w5jhsw	27	35	ticks	tick	NNS
cord-260708-l9w5jhsw	27	36	infesting	infest	VBG
cord-260708-l9w5jhsw	27	37	livestock	livestock	NN
cord-260708-l9w5jhsw	27	38	in	in	IN
cord-260708-l9w5jhsw	27	39	which	which	WDT
cord-260708-l9w5jhsw	27	40	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	27	41	appears	appear	VBZ
cord-260708-l9w5jhsw	27	42	to	to	TO
cord-260708-l9w5jhsw	27	43	be	be	VB
cord-260708-l9w5jhsw	27	44	apathogenic	apathogenic	JJ
cord-260708-l9w5jhsw	27	45	[	[	-LRB-
cord-260708-l9w5jhsw	27	46	27	27	CD
cord-260708-l9w5jhsw	27	47	,	,	,
cord-260708-l9w5jhsw	27	48	46	46	CD
cord-260708-l9w5jhsw	27	49	,	,	,
cord-260708-l9w5jhsw	27	50	146	146	CD
cord-260708-l9w5jhsw	27	51	]	]	-RRB-
cord-260708-l9w5jhsw	27	52	.	.	.
cord-260708-l9w5jhsw	28	1	While	while	IN
cord-260708-l9w5jhsw	28	2	one	one	CD
cord-260708-l9w5jhsw	28	3	case	case	NN
cord-260708-l9w5jhsw	28	4	of	of	IN
cord-260708-l9w5jhsw	28	5	human	human	JJ
cord-260708-l9w5jhsw	28	6	infection	infection	NN
cord-260708-l9w5jhsw	28	7	has	have	VBZ
cord-260708-l9w5jhsw	28	8	been	be	VBN
cord-260708-l9w5jhsw	28	9	described	describe	VBN
cord-260708-l9w5jhsw	28	10	[	[	-LRB-
cord-260708-l9w5jhsw	28	11	27	27	CD
cord-260708-l9w5jhsw	28	12	]	]	-RRB-
cord-260708-l9w5jhsw	28	13	,	,	,
cord-260708-l9w5jhsw	28	14	the	the	DT
cord-260708-l9w5jhsw	28	15	link	link	NN
cord-260708-l9w5jhsw	28	16	to	to	IN
cord-260708-l9w5jhsw	28	17	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	28	18	was	be	VBD
cord-260708-l9w5jhsw	28	19	circumstantial	circumstantial	JJ
cord-260708-l9w5jhsw	28	20	Kupe	Kupe	NNP
cord-260708-l9w5jhsw	28	21	virus	virus	NN
cord-260708-l9w5jhsw	28	22	(	(	-LRB-
cord-260708-l9w5jhsw	28	23	KUPV	KUPV	NNP
cord-260708-l9w5jhsw	28	24	)	)	-RRB-
cord-260708-l9w5jhsw	29	1	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	29	2	-	-	HYPH
cord-260708-l9w5jhsw	29	3	Congo	Congo	NNP
cord-260708-l9w5jhsw	29	4	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	29	5	fever	fever	NN
cord-260708-l9w5jhsw	29	6	group	group	NN
cord-260708-l9w5jhsw	29	7	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	29	8	-	-	HYPH
cord-260708-l9w5jhsw	29	9	Congo	Congo	NNP
cord-260708-l9w5jhsw	29	10	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	29	11	fever	fever	NN
cord-260708-l9w5jhsw	29	12	virus	virus	NN
cord-260708-l9w5jhsw	29	13	(	(	-LRB-
cord-260708-l9w5jhsw	29	14	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	29	15	)	)	-RRB-
cord-260708-l9w5jhsw	30	1	Haemorrhagic	Haemorrhagic	NNP
cord-260708-l9w5jhsw	30	2	fever	fever	NN
cord-260708-l9w5jhsw	30	3	in	in	IN
cord-260708-l9w5jhsw	30	4	man	man	NN
cord-260708-l9w5jhsw	30	5	[	[	-LRB-
cord-260708-l9w5jhsw	30	6	58	58	CD
cord-260708-l9w5jhsw	30	7	,	,	,
cord-260708-l9w5jhsw	30	8	179	179	CD
cord-260708-l9w5jhsw	30	9	,	,	,
cord-260708-l9w5jhsw	30	10	182	182	CD
cord-260708-l9w5jhsw	30	11	]	]	-RRB-
cord-260708-l9w5jhsw	30	12	Hazara	hazara	JJ
cord-260708-l9w5jhsw	30	13	virus	virus	NN
cord-260708-l9w5jhsw	30	14	(	(	-LRB-
cord-260708-l9w5jhsw	30	15	HAZV	HAZV	NNP
cord-260708-l9w5jhsw	30	16	)	)	-RRB-
cord-260708-l9w5jhsw	30	17	Africa	Africa	NNP
cord-260708-l9w5jhsw	30	18	[	[	-LRB-
cord-260708-l9w5jhsw	30	19	47	47	CD
cord-260708-l9w5jhsw	30	20	,	,	,
cord-260708-l9w5jhsw	30	21	106	106	CD
cord-260708-l9w5jhsw	30	22	,	,	,
cord-260708-l9w5jhsw	30	23	187	187	CD
cord-260708-l9w5jhsw	30	24	]	]	-RRB-
cord-260708-l9w5jhsw	30	25	.	.	.
cord-260708-l9w5jhsw	31	1	It	-PRON-	PRP
cord-260708-l9w5jhsw	31	2	is	be	VBZ
cord-260708-l9w5jhsw	31	3	not	not	RB
cord-260708-l9w5jhsw	31	4	possible	possible	JJ
cord-260708-l9w5jhsw	31	5	to	to	TO
cord-260708-l9w5jhsw	31	6	say	say	VB
cord-260708-l9w5jhsw	31	7	yet	yet	RB
cord-260708-l9w5jhsw	31	8	whether	whether	IN
cord-260708-l9w5jhsw	31	9	GV	GV	NNP
cord-260708-l9w5jhsw	31	10	is	be	VBZ
cord-260708-l9w5jhsw	31	11	a	a	DT
cord-260708-l9w5jhsw	31	12	variant	variant	NN
cord-260708-l9w5jhsw	31	13	of	of	IN
cord-260708-l9w5jhsw	31	14	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	31	15	or	or	CC
cord-260708-l9w5jhsw	31	16	vice	vice	NN
cord-260708-l9w5jhsw	31	17	versa	versa	RB
cord-260708-l9w5jhsw	31	18	,	,	,
cord-260708-l9w5jhsw	31	19	but	but	CC
cord-260708-l9w5jhsw	31	20	it	-PRON-	PRP
cord-260708-l9w5jhsw	31	21	is	be	VBZ
cord-260708-l9w5jhsw	31	22	clear	clear	JJ
cord-260708-l9w5jhsw	31	23	that	that	IN
cord-260708-l9w5jhsw	31	24	this	this	DT
cord-260708-l9w5jhsw	31	25	virus	virus	NN
cord-260708-l9w5jhsw	31	26	also	also	RB
cord-260708-l9w5jhsw	31	27	has	have	VBZ
cord-260708-l9w5jhsw	31	28	a	a	DT
cord-260708-l9w5jhsw	31	29	wide	wide	JJ
cord-260708-l9w5jhsw	31	30	distribution	distribution	NN
cord-260708-l9w5jhsw	31	31	.	.	.
cord-260708-l9w5jhsw	32	1	Nairoviruses	Nairoviruses	NNP
cord-260708-l9w5jhsw	32	2	,	,	,
cord-260708-l9w5jhsw	32	3	like	like	IN
cord-260708-l9w5jhsw	32	4	the	the	DT
cord-260708-l9w5jhsw	32	5	members	member	NNS
cord-260708-l9w5jhsw	32	6	of	of	IN
cord-260708-l9w5jhsw	32	7	the	the	DT
cord-260708-l9w5jhsw	32	8	other	other	JJ
cord-260708-l9w5jhsw	32	9	genera	genus	NNS
cord-260708-l9w5jhsw	32	10	of	of	IN
cord-260708-l9w5jhsw	32	11	the	the	DT
cord-260708-l9w5jhsw	32	12	family	family	NN
cord-260708-l9w5jhsw	32	13	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	32	14	,	,	,
cord-260708-l9w5jhsw	32	15	are	be	VBP
cord-260708-l9w5jhsw	32	16	enveloped	envelop	VBN
cord-260708-l9w5jhsw	32	17	viruses	virus	NNS
cord-260708-l9w5jhsw	32	18	that	that	WDT
cord-260708-l9w5jhsw	32	19	appear	appear	VBP
cord-260708-l9w5jhsw	32	20	spherical	spherical	JJ
cord-260708-l9w5jhsw	32	21	in	in	IN
cord-260708-l9w5jhsw	32	22	the	the	DT
cord-260708-l9w5jhsw	32	23	electron	electron	NN
cord-260708-l9w5jhsw	32	24	microscope	microscope	NN
cord-260708-l9w5jhsw	32	25	,	,	,
cord-260708-l9w5jhsw	32	26	with	with	IN
cord-260708-l9w5jhsw	32	27	a	a	DT
cord-260708-l9w5jhsw	32	28	diameter	diameter	NN
cord-260708-l9w5jhsw	32	29	of	of	IN
cord-260708-l9w5jhsw	32	30	approximately	approximately	RB
cord-260708-l9w5jhsw	32	31	100	100	CD
cord-260708-l9w5jhsw	32	32	nm	nm	CD
cord-260708-l9w5jhsw	32	33	[	[	-LRB-
cord-260708-l9w5jhsw	32	34	21	21	CD
cord-260708-l9w5jhsw	32	35	,	,	,
cord-260708-l9w5jhsw	32	36	46	46	CD
cord-260708-l9w5jhsw	32	37	,	,	,
cord-260708-l9w5jhsw	32	38	142	142	CD
cord-260708-l9w5jhsw	32	39	]	]	-RRB-
cord-260708-l9w5jhsw	32	40	.	.	.
cord-260708-l9w5jhsw	33	1	As	as	IN
cord-260708-l9w5jhsw	33	2	with	with	IN
cord-260708-l9w5jhsw	33	3	all	all	DT
cord-260708-l9w5jhsw	33	4	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	33	5	,	,	,
cord-260708-l9w5jhsw	33	6	the	the	DT
cord-260708-l9w5jhsw	33	7	genome	genome	NN
cord-260708-l9w5jhsw	33	8	consists	consist	VBZ
cord-260708-l9w5jhsw	33	9	of	of	IN
cord-260708-l9w5jhsw	33	10	three	three	CD
cord-260708-l9w5jhsw	33	11	segments	segment	NNS
cord-260708-l9w5jhsw	33	12	of	of	IN
cord-260708-l9w5jhsw	33	13	negative	negative	JJ
cord-260708-l9w5jhsw	33	14	-	-	HYPH
cord-260708-l9w5jhsw	33	15	sense	sense	NN
cord-260708-l9w5jhsw	33	16	RNA	RNA	NNP
cord-260708-l9w5jhsw	33	17	[	[	-LRB-
cord-260708-l9w5jhsw	33	18	39	39	CD
cord-260708-l9w5jhsw	33	19	]	]	-RRB-
cord-260708-l9w5jhsw	33	20	(	(	-LRB-
cord-260708-l9w5jhsw	33	21	reviewed	review	VBN
cord-260708-l9w5jhsw	33	22	in	in	IN
cord-260708-l9w5jhsw	33	23	refs	ref	NNS
cord-260708-l9w5jhsw	33	24	.	.	.
cord-260708-l9w5jhsw	34	1	[	[	-LRB-
cord-260708-l9w5jhsw	34	2	109	109	CD
cord-260708-l9w5jhsw	34	3	]	]	-RRB-
cord-260708-l9w5jhsw	34	4	and	and	CC
cord-260708-l9w5jhsw	34	5	[	[	-LRB-
cord-260708-l9w5jhsw	34	6	175	175	CD
cord-260708-l9w5jhsw	34	7	]	]	-RRB-
cord-260708-l9w5jhsw	34	8	)	)	-RRB-
cord-260708-l9w5jhsw	34	9	.	.	.
cord-260708-l9w5jhsw	35	1	These	these	DT
cord-260708-l9w5jhsw	35	2	are	be	VBP
cord-260708-l9w5jhsw	35	3	termed	term	VBN
cord-260708-l9w5jhsw	35	4	the	the	DT
cord-260708-l9w5jhsw	35	5	small	small	JJ
cord-260708-l9w5jhsw	35	6	(	(	-LRB-
cord-260708-l9w5jhsw	35	7	S	s	NN
cord-260708-l9w5jhsw	35	8	)	)	-RRB-
cord-260708-l9w5jhsw	35	9	segment	segment	NN
cord-260708-l9w5jhsw	35	10	,	,	,
cord-260708-l9w5jhsw	35	11	encoding	encode	VBG
cord-260708-l9w5jhsw	35	12	the	the	DT
cord-260708-l9w5jhsw	35	13	nucleocapsid	nucleocapsid	NN
cord-260708-l9w5jhsw	35	14	(	(	-LRB-
cord-260708-l9w5jhsw	35	15	N	N	NNP
cord-260708-l9w5jhsw	35	16	)	)	-RRB-
cord-260708-l9w5jhsw	35	17	protein	protein	NN
cord-260708-l9w5jhsw	35	18	,	,	,
cord-260708-l9w5jhsw	35	19	which	which	WDT
cord-260708-l9w5jhsw	35	20	forms	form	VBZ
cord-260708-l9w5jhsw	35	21	a	a	DT
cord-260708-l9w5jhsw	35	22	complex	complex	NN
cord-260708-l9w5jhsw	35	23	with	with	IN
cord-260708-l9w5jhsw	35	24	each	each	DT
cord-260708-l9w5jhsw	35	25	RNA	RNA	NNP
cord-260708-l9w5jhsw	35	26	segment	segment	NN
cord-260708-l9w5jhsw	35	27	[	[	-LRB-
cord-260708-l9w5jhsw	35	28	24	24	CD
cord-260708-l9w5jhsw	35	29	,	,	,
cord-260708-l9w5jhsw	35	30	39	39	CD
cord-260708-l9w5jhsw	35	31	]	]	-RRB-
cord-260708-l9w5jhsw	35	32	;	;	:
cord-260708-l9w5jhsw	35	33	the	the	DT
cord-260708-l9w5jhsw	35	34	medium	medium	NN
cord-260708-l9w5jhsw	35	35	(	(	-LRB-
cord-260708-l9w5jhsw	35	36	M	M	NNP
cord-260708-l9w5jhsw	35	37	)	)	-RRB-
cord-260708-l9w5jhsw	35	38	segment	segment	NN
cord-260708-l9w5jhsw	35	39	,	,	,
cord-260708-l9w5jhsw	35	40	which	which	WDT
cord-260708-l9w5jhsw	35	41	encodes	encode	VBZ
cord-260708-l9w5jhsw	35	42	a	a	DT
cord-260708-l9w5jhsw	35	43	polyprotein	polyprotein	NN
cord-260708-l9w5jhsw	35	44	that	that	WDT
cord-260708-l9w5jhsw	35	45	is	be	VBZ
cord-260708-l9w5jhsw	35	46	processed	process	VBN
cord-260708-l9w5jhsw	35	47	into	into	IN
cord-260708-l9w5jhsw	35	48	two	two	CD
cord-260708-l9w5jhsw	35	49	mature	mature	JJ
cord-260708-l9w5jhsw	35	50	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	35	51	(	(	-LRB-
cord-260708-l9w5jhsw	35	52	Gn	Gn	NNP
cord-260708-l9w5jhsw	35	53	and	and	CC
cord-260708-l9w5jhsw	35	54	Gc	Gc	NNP
cord-260708-l9w5jhsw	35	55	)	)	-RRB-
cord-260708-l9w5jhsw	35	56	as	as	RB
cord-260708-l9w5jhsw	35	57	well	well	RB
cord-260708-l9w5jhsw	35	58	as	as	IN
cord-260708-l9w5jhsw	35	59	one	one	CD
cord-260708-l9w5jhsw	35	60	or	or	CC
cord-260708-l9w5jhsw	35	61	more	more	JJR
cord-260708-l9w5jhsw	35	62	non	non	JJ
cord-260708-l9w5jhsw	35	63	-	-	JJ
cord-260708-l9w5jhsw	35	64	structural	structural	JJ
cord-260708-l9w5jhsw	35	65	proteins	protein	NNS
cord-260708-l9w5jhsw	35	66	[	[	-LRB-
cord-260708-l9w5jhsw	35	67	3	3	CD
cord-260708-l9w5jhsw	35	68	,	,	,
cord-260708-l9w5jhsw	35	69	17	17	CD
cord-260708-l9w5jhsw	35	70	,	,	,
cord-260708-l9w5jhsw	35	71	39	39	CD
cord-260708-l9w5jhsw	35	72	,	,	,
cord-260708-l9w5jhsw	35	73	107	107	CD
cord-260708-l9w5jhsw	35	74	,	,	,
cord-260708-l9w5jhsw	35	75	144	144	CD
cord-260708-l9w5jhsw	35	76	]	]	-RRB-
cord-260708-l9w5jhsw	35	77	;	;	:
cord-260708-l9w5jhsw	35	78	and	and	CC
cord-260708-l9w5jhsw	35	79	the	the	DT
cord-260708-l9w5jhsw	35	80	large	large	JJ
cord-260708-l9w5jhsw	35	81	(	(	-LRB-
cord-260708-l9w5jhsw	35	82	L	l	NN
cord-260708-l9w5jhsw	35	83	)	)	-RRB-
cord-260708-l9w5jhsw	35	84	segment	segment	NN
cord-260708-l9w5jhsw	35	85	,	,	,
cord-260708-l9w5jhsw	35	86	which	which	WDT
cord-260708-l9w5jhsw	35	87	encodes	encode	VBZ
cord-260708-l9w5jhsw	35	88	the	the	DT
cord-260708-l9w5jhsw	35	89	viral	viral	JJ
cord-260708-l9w5jhsw	35	90	RNA	RNA	NNP
cord-260708-l9w5jhsw	35	91	-	-	HYPH
cord-260708-l9w5jhsw	35	92	dependent	dependent	JJ
cord-260708-l9w5jhsw	35	93	RNA	RNA	NNP
cord-260708-l9w5jhsw	35	94	polymerase	polymerase	NN
cord-260708-l9w5jhsw	35	95	(	(	-LRB-
cord-260708-l9w5jhsw	35	96	RdRp	RdRp	NNP
cord-260708-l9w5jhsw	35	97	)	)	-RRB-
cord-260708-l9w5jhsw	35	98	[	[	-LRB-
cord-260708-l9w5jhsw	35	99	85	85	CD
cord-260708-l9w5jhsw	35	100	,	,	,
cord-260708-l9w5jhsw	35	101	108	108	CD
cord-260708-l9w5jhsw	35	102	]	]	-RRB-
cord-260708-l9w5jhsw	35	103	.	.	.
cord-260708-l9w5jhsw	36	1	Viral	viral	JJ
cord-260708-l9w5jhsw	36	2	replication	replication	NN
cord-260708-l9w5jhsw	36	3	takes	take	VBZ
cord-260708-l9w5jhsw	36	4	place	place	NN
cord-260708-l9w5jhsw	36	5	in	in	IN
cord-260708-l9w5jhsw	36	6	the	the	DT
cord-260708-l9w5jhsw	36	7	cytoplasm	cytoplasm	NN
cord-260708-l9w5jhsw	36	8	,	,	,
cord-260708-l9w5jhsw	36	9	and	and	CC
cord-260708-l9w5jhsw	36	10	viral	viral	JJ
cord-260708-l9w5jhsw	36	11	budding	budding	NN
cord-260708-l9w5jhsw	36	12	occurs	occur	VBZ
cord-260708-l9w5jhsw	36	13	in	in	IN
cord-260708-l9w5jhsw	36	14	the	the	DT
cord-260708-l9w5jhsw	36	15	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	36	16	[	[	-LRB-
cord-260708-l9w5jhsw	36	17	57	57	CD
cord-260708-l9w5jhsw	36	18	,	,	,
cord-260708-l9w5jhsw	36	19	142	142	CD
cord-260708-l9w5jhsw	36	20	]	]	-RRB-
cord-260708-l9w5jhsw	37	1	(	(	-LRB-
cord-260708-l9w5jhsw	37	2	Fig	Fig	NNP
cord-260708-l9w5jhsw	37	3	.	.	.
cord-260708-l9w5jhsw	38	1	1	1	LS
cord-260708-l9w5jhsw	38	2	)	)	-RRB-
cord-260708-l9w5jhsw	38	3	.	.	.
cord-260708-l9w5jhsw	39	1	During	during	IN
cord-260708-l9w5jhsw	39	2	viral	viral	JJ
cord-260708-l9w5jhsw	39	3	replication	replication	NN
cord-260708-l9w5jhsw	39	4	,	,	,
cord-260708-l9w5jhsw	39	5	the	the	DT
cord-260708-l9w5jhsw	39	6	genome	genome	NN
cord-260708-l9w5jhsw	39	7	segments	segment	NNS
cord-260708-l9w5jhsw	39	8	are	be	VBP
cord-260708-l9w5jhsw	39	9	used	use	VBN
cord-260708-l9w5jhsw	39	10	as	as	IN
cord-260708-l9w5jhsw	39	11	the	the	DT
cord-260708-l9w5jhsw	39	12	template	template	NN
cord-260708-l9w5jhsw	39	13	for	for	IN
cord-260708-l9w5jhsw	39	14	synthesis	synthesis	NN
cord-260708-l9w5jhsw	39	15	of	of	IN
cord-260708-l9w5jhsw	39	16	both	both	CC
cord-260708-l9w5jhsw	39	17	mRNA	mRNA	NNP
cord-260708-l9w5jhsw	39	18	(	(	-LRB-
cord-260708-l9w5jhsw	39	19	transcription	transcription	NN
cord-260708-l9w5jhsw	39	20	)	)	-RRB-
cord-260708-l9w5jhsw	39	21	and	and	CC
cord-260708-l9w5jhsw	39	22	complementary	complementary	JJ
cord-260708-l9w5jhsw	39	23	RNA	RNA	NNP
cord-260708-l9w5jhsw	39	24	(	(	-LRB-
cord-260708-l9w5jhsw	39	25	cRNA	cRNA	NNS
cord-260708-l9w5jhsw	39	26	)	)	-RRB-
cord-260708-l9w5jhsw	39	27	(	(	-LRB-
cord-260708-l9w5jhsw	39	28	replication	replication	NN
cord-260708-l9w5jhsw	39	29	)	)	-RRB-
cord-260708-l9w5jhsw	39	30	,	,	,
cord-260708-l9w5jhsw	39	31	where	where	WRB
cord-260708-l9w5jhsw	39	32	cRNAs	crna	NNS
cord-260708-l9w5jhsw	39	33	are	be	VBP
cord-260708-l9w5jhsw	39	34	then	then	RB
cord-260708-l9w5jhsw	39	35	used	use	VBN
cord-260708-l9w5jhsw	39	36	as	as	IN
cord-260708-l9w5jhsw	39	37	the	the	DT
cord-260708-l9w5jhsw	39	38	template	template	NN
cord-260708-l9w5jhsw	39	39	for	for	IN
cord-260708-l9w5jhsw	39	40	the	the	DT
cord-260708-l9w5jhsw	39	41	synthesis	synthesis	NN
cord-260708-l9w5jhsw	39	42	of	of	IN
cord-260708-l9w5jhsw	39	43	progeny	progeny	JJ
cord-260708-l9w5jhsw	39	44	genomic	genomic	JJ
cord-260708-l9w5jhsw	39	45	viral	viral	JJ
cord-260708-l9w5jhsw	39	46	RNA	RNA	NNP
cord-260708-l9w5jhsw	39	47	(	(	-LRB-
cord-260708-l9w5jhsw	39	48	vRNA	vrna	JJ
cord-260708-l9w5jhsw	39	49	)	)	-RRB-
cord-260708-l9w5jhsw	39	50	[	[	-LRB-
cord-260708-l9w5jhsw	39	51	16	16	CD
cord-260708-l9w5jhsw	39	52	]	]	-RRB-
cord-260708-l9w5jhsw	39	53	.	.	.
cord-260708-l9w5jhsw	40	1	The	the	DT
cord-260708-l9w5jhsw	40	2	5	5	CD
cord-260708-l9w5jhsw	40	3	'	'	''
cord-260708-l9w5jhsw	40	4	and	and	CC
cord-260708-l9w5jhsw	40	5	3	3	CD
cord-260708-l9w5jhsw	40	6	'	'	POS
cord-260708-l9w5jhsw	40	7	untranslated	untranslated	JJ
cord-260708-l9w5jhsw	40	8	regions	region	NNS
cord-260708-l9w5jhsw	40	9	(	(	-LRB-
cord-260708-l9w5jhsw	40	10	UTRs	UTRs	NNP
cord-260708-l9w5jhsw	40	11	)	)	-RRB-
cord-260708-l9w5jhsw	40	12	of	of	IN
cord-260708-l9w5jhsw	40	13	the	the	DT
cord-260708-l9w5jhsw	40	14	S	S	NNP
cord-260708-l9w5jhsw	40	15	,	,	,
cord-260708-l9w5jhsw	40	16	M	M	NNP
cord-260708-l9w5jhsw	40	17	and	and	CC
cord-260708-l9w5jhsw	40	18	L	L	NNP
cord-260708-l9w5jhsw	40	19	segments	segment	NNS
cord-260708-l9w5jhsw	40	20	contain	contain	VBP
cord-260708-l9w5jhsw	40	21	the	the	DT
cord-260708-l9w5jhsw	40	22	minimum	minimum	JJ
cord-260708-l9w5jhsw	40	23	cis	cis	NN
cord-260708-l9w5jhsw	40	24	-	-	HYPH
cord-260708-l9w5jhsw	40	25	acting	act	VBG
cord-260708-l9w5jhsw	40	26	elements	element	NNS
cord-260708-l9w5jhsw	40	27	necessary	necessary	JJ
cord-260708-l9w5jhsw	40	28	for	for	IN
cord-260708-l9w5jhsw	40	29	transcription	transcription	NN
cord-260708-l9w5jhsw	40	30	,	,	,
cord-260708-l9w5jhsw	40	31	replication	replication	NN
cord-260708-l9w5jhsw	40	32	and	and	CC
cord-260708-l9w5jhsw	40	33	packaging	packaging	NN
cord-260708-l9w5jhsw	40	34	[	[	-LRB-
cord-260708-l9w5jhsw	40	35	16	16	CD
cord-260708-l9w5jhsw	40	36	,	,	,
cord-260708-l9w5jhsw	40	37	67	67	CD
cord-260708-l9w5jhsw	40	38	]	]	-RRB-
cord-260708-l9w5jhsw	40	39	.	.	.
cord-260708-l9w5jhsw	41	1	The	the	DT
cord-260708-l9w5jhsw	41	2	terminal	terminal	NN
cord-260708-l9w5jhsw	41	3	5	5	CD
cord-260708-l9w5jhsw	41	4	'	'	''
cord-260708-l9w5jhsw	41	5	and	and	CC
cord-260708-l9w5jhsw	41	6	3	3	CD
cord-260708-l9w5jhsw	41	7	'	'	''
cord-260708-l9w5jhsw	41	8	non	non	JJ
cord-260708-l9w5jhsw	41	9	-	-	JJ
cord-260708-l9w5jhsw	41	10	coding	coding	JJ
cord-260708-l9w5jhsw	41	11	regions	region	NNS
cord-260708-l9w5jhsw	41	12	of	of	IN
cord-260708-l9w5jhsw	41	13	each	each	DT
cord-260708-l9w5jhsw	41	14	segment	segment	NN
cord-260708-l9w5jhsw	41	15	are	be	VBP
cord-260708-l9w5jhsw	41	16	complementary	complementary	JJ
cord-260708-l9w5jhsw	41	17	to	to	IN
cord-260708-l9w5jhsw	41	18	each	each	DT
cord-260708-l9w5jhsw	41	19	other	other	JJ
cord-260708-l9w5jhsw	41	20	and	and	CC
cord-260708-l9w5jhsw	41	21	highly	highly	RB
cord-260708-l9w5jhsw	41	22	conserved	conserved	JJ
cord-260708-l9w5jhsw	41	23	among	among	IN
cord-260708-l9w5jhsw	41	24	different	different	JJ
cord-260708-l9w5jhsw	41	25	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	41	26	[	[	-LRB-
cord-260708-l9w5jhsw	41	27	37	37	CD
cord-260708-l9w5jhsw	41	28	]	]	-RRB-
cord-260708-l9w5jhsw	41	29	.	.	.
cord-260708-l9w5jhsw	42	1	The	the	DT
cord-260708-l9w5jhsw	42	2	first	first	JJ
cord-260708-l9w5jhsw	42	3	nine	nine	CD
cord-260708-l9w5jhsw	42	4	nucleotides	nucleotide	NNS
cord-260708-l9w5jhsw	42	5	are	be	VBP
cord-260708-l9w5jhsw	42	6	usually	usually	RB
cord-260708-l9w5jhsw	42	7	the	the	DT
cord-260708-l9w5jhsw	42	8	same	same	JJ
cord-260708-l9w5jhsw	42	9	in	in	IN
cord-260708-l9w5jhsw	42	10	different	different	JJ
cord-260708-l9w5jhsw	42	11	segments	segment	NNS
cord-260708-l9w5jhsw	42	12	,	,	,
cord-260708-l9w5jhsw	42	13	which	which	WDT
cord-260708-l9w5jhsw	42	14	suggests	suggest	VBZ
cord-260708-l9w5jhsw	42	15	that	that	IN
cord-260708-l9w5jhsw	42	16	this	this	DT
cord-260708-l9w5jhsw	42	17	sequence	sequence	NN
cord-260708-l9w5jhsw	42	18	is	be	VBZ
cord-260708-l9w5jhsw	42	19	recognised	recognise	VBN
cord-260708-l9w5jhsw	42	20	by	by	IN
cord-260708-l9w5jhsw	42	21	the	the	DT
cord-260708-l9w5jhsw	42	22	viral	viral	JJ
cord-260708-l9w5jhsw	42	23	polymerase	polymerase	NN
cord-260708-l9w5jhsw	42	24	to	to	TO
cord-260708-l9w5jhsw	42	25	initiate	initiate	VB
cord-260708-l9w5jhsw	42	26	viral	viral	JJ
cord-260708-l9w5jhsw	42	27	transcription/	transcription/	CD
cord-260708-l9w5jhsw	42	28	replication	replication	NN
cord-260708-l9w5jhsw	42	29	[	[	-LRB-
cord-260708-l9w5jhsw	42	30	107	107	CD
cord-260708-l9w5jhsw	42	31	]	]	-RRB-
cord-260708-l9w5jhsw	42	32	.	.	.
cord-260708-l9w5jhsw	43	1	It	-PRON-	PRP
cord-260708-l9w5jhsw	43	2	is	be	VBZ
cord-260708-l9w5jhsw	43	3	not	not	RB
cord-260708-l9w5jhsw	43	4	clear	clear	JJ
cord-260708-l9w5jhsw	43	5	whether	whether	IN
cord-260708-l9w5jhsw	43	6	the	the	DT
cord-260708-l9w5jhsw	43	7	complementarity	complementarity	NN
cord-260708-l9w5jhsw	43	8	between	between	IN
cord-260708-l9w5jhsw	43	9	5	5	CD
cord-260708-l9w5jhsw	43	10	'	'	''
cord-260708-l9w5jhsw	43	11	and	and	CC
cord-260708-l9w5jhsw	43	12	3	3	CD
cord-260708-l9w5jhsw	43	13	'	'	POS
cord-260708-l9w5jhsw	43	14	ends	end	NNS
cord-260708-l9w5jhsw	43	15	reflects	reflect	VBZ
cord-260708-l9w5jhsw	43	16	an	an	DT
cord-260708-l9w5jhsw	43	17	interaction	interaction	NN
cord-260708-l9w5jhsw	43	18	between	between	IN
cord-260708-l9w5jhsw	43	19	the	the	DT
cord-260708-l9w5jhsw	43	20	ends	end	NNS
cord-260708-l9w5jhsw	43	21	of	of	IN
cord-260708-l9w5jhsw	43	22	segments	segment	NNS
cord-260708-l9w5jhsw	43	23	or	or	CC
cord-260708-l9w5jhsw	43	24	the	the	DT
cord-260708-l9w5jhsw	43	25	requirement	requirement	NN
cord-260708-l9w5jhsw	43	26	for	for	IN
cord-260708-l9w5jhsw	43	27	the	the	DT
cord-260708-l9w5jhsw	43	28	same	same	JJ
cord-260708-l9w5jhsw	43	29	3	3	CD
cord-260708-l9w5jhsw	43	30	'	'	''
cord-260708-l9w5jhsw	43	31	sequence	sequence	NN
cord-260708-l9w5jhsw	43	32	in	in	IN
cord-260708-l9w5jhsw	43	33	genome	genome	NN
cord-260708-l9w5jhsw	43	34	and	and	CC
cord-260708-l9w5jhsw	43	35	anti	anti	JJ
cord-260708-l9w5jhsw	43	36	-	-	JJ
cord-260708-l9w5jhsw	43	37	genome	genome	JJ
cord-260708-l9w5jhsw	43	38	RNAs	rna	NNS
cord-260708-l9w5jhsw	43	39	to	to	TO
cord-260708-l9w5jhsw	43	40	act	act	VB
cord-260708-l9w5jhsw	43	41	as	as	IN
cord-260708-l9w5jhsw	43	42	the	the	DT
cord-260708-l9w5jhsw	43	43	attachment	attachment	NN
cord-260708-l9w5jhsw	43	44	site	site	NN
cord-260708-l9w5jhsw	43	45	for	for	IN
cord-260708-l9w5jhsw	43	46	the	the	DT
cord-260708-l9w5jhsw	43	47	viral	viral	JJ
cord-260708-l9w5jhsw	43	48	polymerase	polymerase	NN
cord-260708-l9w5jhsw	43	49	[	[	-LRB-
cord-260708-l9w5jhsw	43	50	14	14	CD
cord-260708-l9w5jhsw	43	51	,	,	,
cord-260708-l9w5jhsw	43	52	66	66	CD
cord-260708-l9w5jhsw	43	53	]	]	-RRB-
cord-260708-l9w5jhsw	43	54	(	(	-LRB-
cord-260708-l9w5jhsw	43	55	reviewed	review	VBN
cord-260708-l9w5jhsw	43	56	in	in	IN
cord-260708-l9w5jhsw	43	57	refs	ref	NNS
cord-260708-l9w5jhsw	43	58	.	.	.
cord-260708-l9w5jhsw	44	1	[	[	-LRB-
cord-260708-l9w5jhsw	44	2	109	109	CD
cord-260708-l9w5jhsw	44	3	]	]	-RRB-
cord-260708-l9w5jhsw	44	4	and	and	CC
cord-260708-l9w5jhsw	44	5	[	[	-LRB-
cord-260708-l9w5jhsw	44	6	147	147	CD
cord-260708-l9w5jhsw	44	7	]	]	-RRB-
cord-260708-l9w5jhsw	44	8	)	)	-RRB-
cord-260708-l9w5jhsw	44	9	.	.	.
cord-260708-l9w5jhsw	45	1	As	as	IN
cord-260708-l9w5jhsw	45	2	with	with	IN
cord-260708-l9w5jhsw	45	3	other	other	JJ
cord-260708-l9w5jhsw	45	4	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	45	5	,	,	,
cord-260708-l9w5jhsw	45	6	the	the	DT
cord-260708-l9w5jhsw	45	7	nairoviruses	nairoviruses	NNPS
cord-260708-l9w5jhsw	45	8	utilise	utilise	VBP
cord-260708-l9w5jhsw	45	9	capped	cap	VBN
cord-260708-l9w5jhsw	45	10	primers	primer	NNS
cord-260708-l9w5jhsw	45	11	snatched	snatch	VBN
cord-260708-l9w5jhsw	45	12	from	from	IN
cord-260708-l9w5jhsw	45	13	host	host	NN
cord-260708-l9w5jhsw	45	14	mRNA	mrna	NN
cord-260708-l9w5jhsw	45	15	for	for	IN
cord-260708-l9w5jhsw	45	16	initiation	initiation	NN
cord-260708-l9w5jhsw	45	17	of	of	IN
cord-260708-l9w5jhsw	45	18	their	-PRON-	PRP$
cord-260708-l9w5jhsw	45	19	mRNA	mrna	NN
cord-260708-l9w5jhsw	45	20	transcription	transcription	NN
cord-260708-l9w5jhsw	45	21	[	[	-LRB-
cord-260708-l9w5jhsw	45	22	90	90	CD
cord-260708-l9w5jhsw	45	23	]	]	-RRB-
cord-260708-l9w5jhsw	45	24	.	.	.
cord-260708-l9w5jhsw	46	1	The	the	DT
cord-260708-l9w5jhsw	46	2	initiation	initiation	NN
cord-260708-l9w5jhsw	46	3	of	of	IN
cord-260708-l9w5jhsw	46	4	cRNA	crna	JJ
cord-260708-l9w5jhsw	46	5	and	and	CC
cord-260708-l9w5jhsw	46	6	vRNA	vrna	JJ
cord-260708-l9w5jhsw	46	7	synthesis	synthesis	NN
cord-260708-l9w5jhsw	46	8	occurs	occur	VBZ
cord-260708-l9w5jhsw	46	9	by	by	IN
cord-260708-l9w5jhsw	46	10	a	a	DT
cord-260708-l9w5jhsw	46	11	different	different	JJ
cord-260708-l9w5jhsw	46	12	mechanism	mechanism	NN
cord-260708-l9w5jhsw	46	13	,	,	,
cord-260708-l9w5jhsw	46	14	which	which	WDT
cord-260708-l9w5jhsw	46	15	has	have	VBZ
cord-260708-l9w5jhsw	46	16	not	not	RB
cord-260708-l9w5jhsw	46	17	yet	yet	RB
cord-260708-l9w5jhsw	46	18	been	be	VBN
cord-260708-l9w5jhsw	46	19	fully	fully	RB
cord-260708-l9w5jhsw	46	20	worked	work	VBN
cord-260708-l9w5jhsw	46	21	out	out	RP
cord-260708-l9w5jhsw	46	22	.	.	.
cord-260708-l9w5jhsw	47	1	The	the	DT
cord-260708-l9w5jhsw	47	2	fact	fact	NN
cord-260708-l9w5jhsw	47	3	that	that	IN
cord-260708-l9w5jhsw	47	4	polymerase	polymerase	NN
cord-260708-l9w5jhsw	47	5	slippage	slippage	NN
cord-260708-l9w5jhsw	47	6	occurs	occur	VBZ
cord-260708-l9w5jhsw	47	7	during	during	IN
cord-260708-l9w5jhsw	47	8	mRNA	mRNA	NNP
cord-260708-l9w5jhsw	47	9	synthesis	synthesis	NNP
cord-260708-l9w5jhsw	47	10	[	[	-LRB-
cord-260708-l9w5jhsw	47	11	90	90	CD
cord-260708-l9w5jhsw	47	12	]	]	-RRB-
cord-260708-l9w5jhsw	47	13	,	,	,
cord-260708-l9w5jhsw	47	14	coupled	couple	VBN
cord-260708-l9w5jhsw	47	15	with	with	IN
cord-260708-l9w5jhsw	47	16	the	the	DT
cord-260708-l9w5jhsw	47	17	observation	observation	NN
cord-260708-l9w5jhsw	47	18	that	that	IN
cord-260708-l9w5jhsw	47	19	the	the	DT
cord-260708-l9w5jhsw	47	20	RNA	RNA	NNP
cord-260708-l9w5jhsw	47	21	segments	segment	NNS
cord-260708-l9w5jhsw	47	22	of	of	IN
cord-260708-l9w5jhsw	47	23	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	47	24	,	,	,
cord-260708-l9w5jhsw	47	25	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	47	26	and	and	CC
cord-260708-l9w5jhsw	47	27	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	47	28	contain	contain	VBP
cord-260708-l9w5jhsw	47	29	a	a	DT
cord-260708-l9w5jhsw	47	30	5'-terminal	5'-terminal	CD
cord-260708-l9w5jhsw	47	31	pyrimidine	pyrimidine	NN
cord-260708-l9w5jhsw	47	32	[	[	-LRB-
cord-260708-l9w5jhsw	47	33	90	90	CD
cord-260708-l9w5jhsw	47	34	,	,	,
cord-260708-l9w5jhsw	47	35	144	144	CD
cord-260708-l9w5jhsw	47	36	,	,	,
cord-260708-l9w5jhsw	47	37	187	187	CD
cord-260708-l9w5jhsw	47	38	]	]	-RRB-
cord-260708-l9w5jhsw	47	39	,	,	,
cord-260708-l9w5jhsw	47	40	while	while	IN
cord-260708-l9w5jhsw	47	41	viral	viral	JJ
cord-260708-l9w5jhsw	47	42	RNA	RNA	NNP
cord-260708-l9w5jhsw	47	43	polymerases	polymerase	NNS
cord-260708-l9w5jhsw	47	44	can	can	MD
cord-260708-l9w5jhsw	47	45	initiate	initiate	VB
cord-260708-l9w5jhsw	47	46	RNA	RNA	NNP
cord-260708-l9w5jhsw	47	47	synthesis	synthesis	NN
cord-260708-l9w5jhsw	47	48	only	only	RB
cord-260708-l9w5jhsw	47	49	by	by	IN
cord-260708-l9w5jhsw	47	50	attaching	attach	VBG
cord-260708-l9w5jhsw	47	51	purines	purine	NNS
cord-260708-l9w5jhsw	47	52	[	[	-LRB-
cord-260708-l9w5jhsw	47	53	12	12	CD
cord-260708-l9w5jhsw	47	54	]	]	-RRB-
cord-260708-l9w5jhsw	47	55	,	,	,
cord-260708-l9w5jhsw	47	56	suggests	suggest	VBZ
cord-260708-l9w5jhsw	47	57	that	that	IN
cord-260708-l9w5jhsw	47	58	initiation	initiation	NN
cord-260708-l9w5jhsw	47	59	of	of	IN
cord-260708-l9w5jhsw	47	60	RNA	RNA	NNP
cord-260708-l9w5jhsw	47	61	replication	replication	NN
cord-260708-l9w5jhsw	47	62	occurs	occur	VBZ
cord-260708-l9w5jhsw	47	63	in	in	IN
cord-260708-l9w5jhsw	47	64	a	a	DT
cord-260708-l9w5jhsw	47	65	prime	prime	JJ
cord-260708-l9w5jhsw	47	66	-	-	HYPH
cord-260708-l9w5jhsw	47	67	and	and	CC
cord-260708-l9w5jhsw	47	68	-	-	HYPH
cord-260708-l9w5jhsw	47	69	realign	realign	NN
cord-260708-l9w5jhsw	47	70	manner	manner	NN
cord-260708-l9w5jhsw	47	71	.	.	.
cord-260708-l9w5jhsw	48	1	The	the	DT
cord-260708-l9w5jhsw	48	2	two	two	CD
cord-260708-l9w5jhsw	48	3	membrane	membrane	NN
cord-260708-l9w5jhsw	48	4	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	48	5	(	(	-LRB-
cord-260708-l9w5jhsw	48	6	Gn	Gn	NNP
cord-260708-l9w5jhsw	48	7	and	and	CC
cord-260708-l9w5jhsw	48	8	Gc	Gc	NNP
cord-260708-l9w5jhsw	48	9	)	)	-RRB-
cord-260708-l9w5jhsw	48	10	are	be	VBP
cord-260708-l9w5jhsw	48	11	believed	believe	VBN
cord-260708-l9w5jhsw	48	12	to	to	TO
cord-260708-l9w5jhsw	48	13	determine	determine	VB
cord-260708-l9w5jhsw	48	14	cell	cell	NN
cord-260708-l9w5jhsw	48	15	tropism	tropism	NN
cord-260708-l9w5jhsw	48	16	and	and	CC
cord-260708-l9w5jhsw	48	17	the	the	DT
cord-260708-l9w5jhsw	48	18	ability	ability	NN
cord-260708-l9w5jhsw	48	19	of	of	IN
cord-260708-l9w5jhsw	48	20	the	the	DT
cord-260708-l9w5jhsw	48	21	viruses	virus	NNS
cord-260708-l9w5jhsw	48	22	to	to	TO
cord-260708-l9w5jhsw	48	23	infect	infect	VB
cord-260708-l9w5jhsw	48	24	susceptible	susceptible	JJ
cord-260708-l9w5jhsw	48	25	cells	cell	NNS
cord-260708-l9w5jhsw	48	26	via	via	IN
cord-260708-l9w5jhsw	48	27	recognition	recognition	NN
cord-260708-l9w5jhsw	48	28	and	and	CC
cord-260708-l9w5jhsw	48	29	binding	binding	NN
cord-260708-l9w5jhsw	48	30	of	of	IN
cord-260708-l9w5jhsw	48	31	one	one	CD
cord-260708-l9w5jhsw	48	32	or	or	CC
cord-260708-l9w5jhsw	48	33	more	more	JJR
cord-260708-l9w5jhsw	48	34	cellular	cellular	JJ
cord-260708-l9w5jhsw	48	35	receptors	receptor	NNS
cord-260708-l9w5jhsw	48	36	.	.	.
cord-260708-l9w5jhsw	49	1	The	the	DT
cord-260708-l9w5jhsw	49	2	specific	specific	JJ
cord-260708-l9w5jhsw	49	3	cellular	cellular	JJ
cord-260708-l9w5jhsw	49	4	receptor(s	receptor(s	NN
cord-260708-l9w5jhsw	49	5	)	)	-RRB-
cord-260708-l9w5jhsw	49	6	used	use	VBN
cord-260708-l9w5jhsw	49	7	by	by	IN
cord-260708-l9w5jhsw	49	8	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	49	9	are	be	VBP
cord-260708-l9w5jhsw	49	10	currently	currently	RB
cord-260708-l9w5jhsw	49	11	unknown	unknown	JJ
cord-260708-l9w5jhsw	49	12	,	,	,
cord-260708-l9w5jhsw	49	13	but	but	CC
cord-260708-l9w5jhsw	49	14	the	the	DT
cord-260708-l9w5jhsw	49	15	Gc	Gc	NNP
cord-260708-l9w5jhsw	49	16	protein	protein	NN
cord-260708-l9w5jhsw	49	17	is	be	VBZ
cord-260708-l9w5jhsw	49	18	thought	think	VBN
cord-260708-l9w5jhsw	49	19	to	to	TO
cord-260708-l9w5jhsw	49	20	be	be	VB
cord-260708-l9w5jhsw	49	21	involved	involve	VBN
cord-260708-l9w5jhsw	49	22	in	in	IN
cord-260708-l9w5jhsw	49	23	virus	virus	NN
cord-260708-l9w5jhsw	49	24	attachment	attachment	NN
cord-260708-l9w5jhsw	49	25	to	to	IN
cord-260708-l9w5jhsw	49	26	the	the	DT
cord-260708-l9w5jhsw	49	27	target	target	NN
cord-260708-l9w5jhsw	49	28	cell	cell	NN
cord-260708-l9w5jhsw	49	29	receptor	receptor	NN
cord-260708-l9w5jhsw	49	30	,	,	,
cord-260708-l9w5jhsw	49	31	as	as	IN
cord-260708-l9w5jhsw	49	32	antibodies	antibody	NNS
cord-260708-l9w5jhsw	49	33	against	against	IN
cord-260708-l9w5jhsw	49	34	Gc	Gc	NNP
cord-260708-l9w5jhsw	49	35	,	,	,
cord-260708-l9w5jhsw	49	36	but	but	CC
cord-260708-l9w5jhsw	49	37	not	not	RB
cord-260708-l9w5jhsw	49	38	Gn	Gn	NNP
cord-260708-l9w5jhsw	49	39	,	,	,
cord-260708-l9w5jhsw	49	40	appear	appear	VBP
cord-260708-l9w5jhsw	49	41	to	to	TO
cord-260708-l9w5jhsw	49	42	protect	protect	VB
cord-260708-l9w5jhsw	49	43	cells	cell	NNS
cord-260708-l9w5jhsw	49	44	from	from	IN
cord-260708-l9w5jhsw	49	45	CCHFV	cchfv	NN
cord-260708-l9w5jhsw	49	46	infection	infection	NN
cord-260708-l9w5jhsw	49	47	in	in	IN
cord-260708-l9w5jhsw	49	48	plaque	plaque	NN
cord-260708-l9w5jhsw	49	49	reduction	reduction	NN
cord-260708-l9w5jhsw	49	50	neutralisation	neutralisation	NN
cord-260708-l9w5jhsw	49	51	assays	assay	NNS
cord-260708-l9w5jhsw	49	52	[	[	-LRB-
cord-260708-l9w5jhsw	49	53	1	1	CD
cord-260708-l9w5jhsw	49	54	,	,	,
cord-260708-l9w5jhsw	49	55	17	17	CD
cord-260708-l9w5jhsw	49	56	]	]	-RRB-
cord-260708-l9w5jhsw	49	57	.	.	.
cord-260708-l9w5jhsw	50	1	The	the	DT
cord-260708-l9w5jhsw	50	2	ectodomain	ectodomain	NN
cord-260708-l9w5jhsw	50	3	of	of	IN
cord-260708-l9w5jhsw	50	4	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	50	5	Gc	Gc	NNP
cord-260708-l9w5jhsw	50	6	contains	contain	VBZ
cord-260708-l9w5jhsw	50	7	an	an	DT
cord-260708-l9w5jhsw	50	8	epitope	epitope	NN
cord-260708-l9w5jhsw	50	9	that	that	WDT
cord-260708-l9w5jhsw	50	10	is	be	VBZ
cord-260708-l9w5jhsw	50	11	highly	highly	RB
cord-260708-l9w5jhsw	50	12	conserved	conserve	VBN
cord-260708-l9w5jhsw	50	13	among	among	IN
cord-260708-l9w5jhsw	50	14	strains	strain	NNS
cord-260708-l9w5jhsw	50	15	[	[	-LRB-
cord-260708-l9w5jhsw	50	16	1	1	CD
cord-260708-l9w5jhsw	50	17	]	]	-RRB-
cord-260708-l9w5jhsw	50	18	.	.	.
cord-260708-l9w5jhsw	51	1	This	this	DT
cord-260708-l9w5jhsw	51	2	fragment	fragment	NN
cord-260708-l9w5jhsw	51	3	is	be	VBZ
cord-260708-l9w5jhsw	51	4	probably	probably	RB
cord-260708-l9w5jhsw	51	5	exposed	expose	VBN
cord-260708-l9w5jhsw	51	6	in	in	IN
cord-260708-l9w5jhsw	51	7	the	the	DT
cord-260708-l9w5jhsw	51	8	virus	virus	NN
cord-260708-l9w5jhsw	51	9	,	,	,
cord-260708-l9w5jhsw	51	10	as	as	IN
cord-260708-l9w5jhsw	51	11	antibodies	antibody	NNS
cord-260708-l9w5jhsw	51	12	against	against	IN
cord-260708-l9w5jhsw	51	13	this	this	DT
cord-260708-l9w5jhsw	51	14	epitope	epitope	NN
cord-260708-l9w5jhsw	51	15	are	be	VBP
cord-260708-l9w5jhsw	51	16	neutralising	neutralise	VBG
cord-260708-l9w5jhsw	51	17	for	for	IN
cord-260708-l9w5jhsw	51	18	different	different	JJ
cord-260708-l9w5jhsw	51	19	strains	strain	NNS
cord-260708-l9w5jhsw	51	20	of	of	IN
cord-260708-l9w5jhsw	51	21	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	51	22	and	and	CC
cord-260708-l9w5jhsw	51	23	protect	protect	VB
cord-260708-l9w5jhsw	51	24	mice	mouse	NNS
cord-260708-l9w5jhsw	51	25	from	from	IN
cord-260708-l9w5jhsw	51	26	challenge	challenge	NN
cord-260708-l9w5jhsw	51	27	with	with	IN
cord-260708-l9w5jhsw	51	28	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	51	29	[	[	-LRB-
cord-260708-l9w5jhsw	51	30	1	1	CD
cord-260708-l9w5jhsw	51	31	]	]	-RRB-
cord-260708-l9w5jhsw	51	32	.	.	.
cord-260708-l9w5jhsw	52	1	Similarly	similarly	RB
cord-260708-l9w5jhsw	52	2	,	,	,
cord-260708-l9w5jhsw	52	3	the	the	DT
cord-260708-l9w5jhsw	52	4	Gc	Gc	NNP
cord-260708-l9w5jhsw	52	5	of	of	IN
cord-260708-l9w5jhsw	52	6	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	52	7	was	be	VBD
cord-260708-l9w5jhsw	52	8	also	also	RB
cord-260708-l9w5jhsw	52	9	demonstrated	demonstrate	VBN
cord-260708-l9w5jhsw	52	10	to	to	TO
cord-260708-l9w5jhsw	52	11	be	be	VB
cord-260708-l9w5jhsw	52	12	targeted	target	VBN
cord-260708-l9w5jhsw	52	13	by	by	IN
cord-260708-l9w5jhsw	52	14	neutralising	neutralise	VBG
cord-260708-l9w5jhsw	52	15	antibodies	antibody	NNS
cord-260708-l9w5jhsw	52	16	[	[	-LRB-
cord-260708-l9w5jhsw	52	17	107	107	CD
cord-260708-l9w5jhsw	52	18	]	]	-RRB-
cord-260708-l9w5jhsw	52	19	.	.	.
cord-260708-l9w5jhsw	53	1	Antibodies	antibody	NNS
cord-260708-l9w5jhsw	53	2	to	to	IN
cord-260708-l9w5jhsw	53	3	the	the	DT
cord-260708-l9w5jhsw	53	4	Gn	Gn	NNP
cord-260708-l9w5jhsw	53	5	protein	protein	NN
cord-260708-l9w5jhsw	53	6	were	be	VBD
cord-260708-l9w5jhsw	53	7	found	find	VBN
cord-260708-l9w5jhsw	53	8	to	to	TO
cord-260708-l9w5jhsw	53	9	be	be	VB
cord-260708-l9w5jhsw	53	10	non	non	JJ
cord-260708-l9w5jhsw	53	11	-	-	JJ
cord-260708-l9w5jhsw	53	12	neutralising	neutralising	JJ
cord-260708-l9w5jhsw	53	13	in	in	IN
cord-260708-l9w5jhsw	53	14	vitro	vitro	FW
cord-260708-l9w5jhsw	53	15	,	,	,
cord-260708-l9w5jhsw	53	16	though	though	IN
cord-260708-l9w5jhsw	53	17	could	could	MD
cord-260708-l9w5jhsw	53	18	still	still	RB
cord-260708-l9w5jhsw	53	19	be	be	VB
cord-260708-l9w5jhsw	53	20	protective	protective	JJ
cord-260708-l9w5jhsw	53	21	in	in	IN
cord-260708-l9w5jhsw	53	22	vivo	vivo	NNP
cord-260708-l9w5jhsw	53	23	[	[	-LRB-
cord-260708-l9w5jhsw	53	24	17	17	CD
cord-260708-l9w5jhsw	53	25	]	]	-RRB-
cord-260708-l9w5jhsw	53	26	.	.	.
cord-260708-l9w5jhsw	54	1	Based	base	VBN
cord-260708-l9w5jhsw	54	2	on	on	IN
cord-260708-l9w5jhsw	54	3	the	the	DT
cord-260708-l9w5jhsw	54	4	finding	finding	NN
cord-260708-l9w5jhsw	54	5	that	that	IN
cord-260708-l9w5jhsw	54	6	an	an	DT
cord-260708-l9w5jhsw	54	7	independently	independently	RB
cord-260708-l9w5jhsw	54	8	folding	fold	VBG
cord-260708-l9w5jhsw	54	9	section	section	NN
cord-260708-l9w5jhsw	54	10	of	of	IN
cord-260708-l9w5jhsw	54	11	this	this	DT
cord-260708-l9w5jhsw	54	12	Gc	Gc	NNP
cord-260708-l9w5jhsw	54	13	protein	protein	NN
cord-260708-l9w5jhsw	54	14	bound	bind	VBN
cord-260708-l9w5jhsw	54	15	to	to	IN
cord-260708-l9w5jhsw	54	16	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	54	17	-	-	HYPH
cord-260708-l9w5jhsw	54	18	susceptible	susceptible	JJ
cord-260708-l9w5jhsw	54	19	cells	cell	NNS
cord-260708-l9w5jhsw	54	20	,	,	,
cord-260708-l9w5jhsw	54	21	and	and	CC
cord-260708-l9w5jhsw	54	22	using	use	VBG
cord-260708-l9w5jhsw	54	23	this	this	DT
cord-260708-l9w5jhsw	54	24	part	part	NN
cord-260708-l9w5jhsw	54	25	of	of	IN
cord-260708-l9w5jhsw	54	26	Gc	Gc	NNP
cord-260708-l9w5jhsw	54	27	as	as	IN
cord-260708-l9w5jhsw	54	28	a	a	DT
cord-260708-l9w5jhsw	54	29	probe	probe	NN
cord-260708-l9w5jhsw	54	30	[	[	-LRB-
cord-260708-l9w5jhsw	54	31	185	185	CD
cord-260708-l9w5jhsw	54	32	]	]	-RRB-
cord-260708-l9w5jhsw	54	33	,	,	,
cord-260708-l9w5jhsw	54	34	nucleolin	nucleolin	NNP
cord-260708-l9w5jhsw	54	35	has	have	VBZ
cord-260708-l9w5jhsw	54	36	been	be	VBN
cord-260708-l9w5jhsw	54	37	suggested	suggest	VBN
cord-260708-l9w5jhsw	54	38	as	as	IN
cord-260708-l9w5jhsw	54	39	a	a	DT
cord-260708-l9w5jhsw	54	40	putative	putative	JJ
cord-260708-l9w5jhsw	54	41	CCHFV	cchfv	NN
cord-260708-l9w5jhsw	54	42	receptor	receptor	NN
cord-260708-l9w5jhsw	54	43	.	.	.
cord-260708-l9w5jhsw	55	1	Nucleolin	Nucleolin	NNP
cord-260708-l9w5jhsw	55	2	is	be	VBZ
cord-260708-l9w5jhsw	55	3	a	a	DT
cord-260708-l9w5jhsw	55	4	cellular	cellular	JJ
cord-260708-l9w5jhsw	55	5	protein	protein	NN
cord-260708-l9w5jhsw	55	6	that	that	WDT
cord-260708-l9w5jhsw	55	7	is	be	VBZ
cord-260708-l9w5jhsw	55	8	abundant	abundant	JJ
cord-260708-l9w5jhsw	55	9	in	in	IN
cord-260708-l9w5jhsw	55	10	the	the	DT
cord-260708-l9w5jhsw	55	11	nucleus	nucleus	NN
cord-260708-l9w5jhsw	55	12	but	but	CC
cord-260708-l9w5jhsw	55	13	can	can	MD
cord-260708-l9w5jhsw	55	14	also	also	RB
cord-260708-l9w5jhsw	55	15	be	be	VB
cord-260708-l9w5jhsw	55	16	expressed	express	VBN
cord-260708-l9w5jhsw	55	17	on	on	IN
cord-260708-l9w5jhsw	55	18	the	the	DT
cord-260708-l9w5jhsw	55	19	cell	cell	NN
cord-260708-l9w5jhsw	55	20	surface	surface	NN
cord-260708-l9w5jhsw	55	21	of	of	IN
cord-260708-l9w5jhsw	55	22	several	several	JJ
cord-260708-l9w5jhsw	55	23	cell	cell	NN
cord-260708-l9w5jhsw	55	24	types	type	NNS
cord-260708-l9w5jhsw	55	25	[	[	-LRB-
cord-260708-l9w5jhsw	55	26	36	36	CD
cord-260708-l9w5jhsw	55	27	,	,	,
cord-260708-l9w5jhsw	55	28	83	83	CD
cord-260708-l9w5jhsw	55	29	,	,	,
cord-260708-l9w5jhsw	55	30	148	148	CD
cord-260708-l9w5jhsw	55	31	,	,	,
cord-260708-l9w5jhsw	55	32	149	149	CD
cord-260708-l9w5jhsw	55	33	,	,	,
cord-260708-l9w5jhsw	55	34	151	151	CD
cord-260708-l9w5jhsw	55	35	]	]	-RRB-
cord-260708-l9w5jhsw	55	36	,	,	,
cord-260708-l9w5jhsw	55	37	including	include	VBG
cord-260708-l9w5jhsw	55	38	mononuclear	mononuclear	JJ
cord-260708-l9w5jhsw	55	39	phagocytes	phagocyte	NNS
cord-260708-l9w5jhsw	55	40	,	,	,
cord-260708-l9w5jhsw	55	41	endothelial	endothelial	JJ
cord-260708-l9w5jhsw	55	42	cells	cell	NNS
cord-260708-l9w5jhsw	55	43	and	and	CC
cord-260708-l9w5jhsw	55	44	hepatocytes	hepatocyte	NNS
cord-260708-l9w5jhsw	55	45	which	which	WDT
cord-260708-l9w5jhsw	55	46	are	be	VBP
cord-260708-l9w5jhsw	55	47	known	know	VBN
cord-260708-l9w5jhsw	55	48	to	to	TO
cord-260708-l9w5jhsw	55	49	be	be	VB
cord-260708-l9w5jhsw	55	50	targets	target	NNS
cord-260708-l9w5jhsw	55	51	for	for	IN
cord-260708-l9w5jhsw	55	52	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	55	53	[	[	-LRB-
cord-260708-l9w5jhsw	55	54	28	28	CD
cord-260708-l9w5jhsw	55	55	,	,	,
cord-260708-l9w5jhsw	55	56	185	185	CD
cord-260708-l9w5jhsw	55	57	]	]	-RRB-
cord-260708-l9w5jhsw	55	58	.	.	.
cord-260708-l9w5jhsw	56	1	Although	although	IN
cord-260708-l9w5jhsw	56	2	nucleolin	nucleolin	NNP
cord-260708-l9w5jhsw	56	3	has	have	VBZ
cord-260708-l9w5jhsw	56	4	also	also	RB
cord-260708-l9w5jhsw	56	5	been	be	VBN
cord-260708-l9w5jhsw	56	6	suggested	suggest	VBN
cord-260708-l9w5jhsw	56	7	to	to	TO
cord-260708-l9w5jhsw	56	8	act	act	VB
cord-260708-l9w5jhsw	56	9	as	as	IN
cord-260708-l9w5jhsw	56	10	a	a	DT
cord-260708-l9w5jhsw	56	11	receptor	receptor	NN
cord-260708-l9w5jhsw	56	12	for	for	IN
cord-260708-l9w5jhsw	56	13	several	several	JJ
cord-260708-l9w5jhsw	56	14	other	other	JJ
cord-260708-l9w5jhsw	56	15	viruses	virus	NNS
cord-260708-l9w5jhsw	56	16	,	,	,
cord-260708-l9w5jhsw	56	17	such	such	JJ
cord-260708-l9w5jhsw	56	18	as	as	IN
cord-260708-l9w5jhsw	56	19	parainfluenza	parainfluenza	NNP
cord-260708-l9w5jhsw	56	20	virus	virus	NNP
cord-260708-l9w5jhsw	56	21	type	type	NNP
cord-260708-l9w5jhsw	56	22	3	3	CD
cord-260708-l9w5jhsw	56	23	[	[	-LRB-
cord-260708-l9w5jhsw	56	24	22	22	CD
cord-260708-l9w5jhsw	56	25	]	]	-RRB-
cord-260708-l9w5jhsw	56	26	,	,	,
cord-260708-l9w5jhsw	56	27	human	human	JJ
cord-260708-l9w5jhsw	56	28	immunodeficiency	immunodeficiency	NN
cord-260708-l9w5jhsw	56	29	virus	virus	NN
cord-260708-l9w5jhsw	56	30	(	(	-LRB-
cord-260708-l9w5jhsw	56	31	HIV	HIV	NNP
cord-260708-l9w5jhsw	56	32	)	)	-RRB-
cord-260708-l9w5jhsw	56	33	[	[	-LRB-
cord-260708-l9w5jhsw	56	34	118	118	CD
cord-260708-l9w5jhsw	56	35	]	]	-RRB-
cord-260708-l9w5jhsw	56	36	,	,	,
cord-260708-l9w5jhsw	56	37	coxsackie	coxsackie	NNP
cord-260708-l9w5jhsw	56	38	B	B	NNP
cord-260708-l9w5jhsw	56	39	virus	virus	NN
cord-260708-l9w5jhsw	56	40	[	[	-LRB-
cord-260708-l9w5jhsw	56	41	49	49	CD
cord-260708-l9w5jhsw	56	42	]	]	-RRB-
cord-260708-l9w5jhsw	56	43	and	and	CC
cord-260708-l9w5jhsw	56	44	respiratory	respiratory	JJ
cord-260708-l9w5jhsw	56	45	syncytial	syncytial	JJ
cord-260708-l9w5jhsw	56	46	virus	virus	NN
cord-260708-l9w5jhsw	56	47	(	(	-LRB-
cord-260708-l9w5jhsw	56	48	RSV	RSV	NNP
cord-260708-l9w5jhsw	56	49	)	)	-RRB-
cord-260708-l9w5jhsw	56	50	[	[	-LRB-
cord-260708-l9w5jhsw	56	51	162	162	CD
cord-260708-l9w5jhsw	56	52	]	]	-RRB-
cord-260708-l9w5jhsw	56	53	,	,	.
cord-260708-l9w5jhsw	57	1	further	further	JJ
cord-260708-l9w5jhsw	57	2	studies	study	NNS
cord-260708-l9w5jhsw	57	3	are	be	VBP
cord-260708-l9w5jhsw	57	4	required	require	VBN
cord-260708-l9w5jhsw	57	5	to	to	TO
cord-260708-l9w5jhsw	57	6	determine	determine	VB
cord-260708-l9w5jhsw	57	7	whether	whether	IN
cord-260708-l9w5jhsw	57	8	nucleolin	nucleolin	NNP
cord-260708-l9w5jhsw	57	9	acts	act	NNS
cord-260708-l9w5jhsw	57	10	as	as	IN
cord-260708-l9w5jhsw	57	11	the	the	DT
cord-260708-l9w5jhsw	57	12	primary	primary	JJ
cord-260708-l9w5jhsw	57	13	receptor	receptor	NN
cord-260708-l9w5jhsw	57	14	for	for	IN
cord-260708-l9w5jhsw	57	15	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	57	16	;	;	:
cord-260708-l9w5jhsw	57	17	in	in	IN
cord-260708-l9w5jhsw	57	18	particular	particular	JJ
cord-260708-l9w5jhsw	57	19	,	,	,
cord-260708-l9w5jhsw	57	20	infection	infection	NN
cord-260708-l9w5jhsw	57	21	studies	study	NNS
cord-260708-l9w5jhsw	57	22	with	with	IN
cord-260708-l9w5jhsw	57	23	wild	wild	JJ
cord-260708-l9w5jhsw	57	24	-	-	HYPH
cord-260708-l9w5jhsw	57	25	type	type	NN
cord-260708-l9w5jhsw	57	26	(	(	-LRB-
cord-260708-l9w5jhsw	57	27	not	not	RB
cord-260708-l9w5jhsw	57	28	cell	cell	NN
cord-260708-l9w5jhsw	57	29	-	-	HYPH
cord-260708-l9w5jhsw	57	30	culture	culture	NN
cord-260708-l9w5jhsw	57	31	-	-	HYPH
cord-260708-l9w5jhsw	57	32	adapted	adapt	VBN
cord-260708-l9w5jhsw	57	33	)	)	-RRB-
cord-260708-l9w5jhsw	57	34	viruses	virus	NNS
cord-260708-l9w5jhsw	57	35	are	be	VBP
cord-260708-l9w5jhsw	57	36	required	require	VBN
cord-260708-l9w5jhsw	57	37	to	to	TO
cord-260708-l9w5jhsw	57	38	confirm	confirm	VB
cord-260708-l9w5jhsw	57	39	the	the	DT
cord-260708-l9w5jhsw	57	40	biological	biological	JJ
cord-260708-l9w5jhsw	57	41	relevance	relevance	NN
cord-260708-l9w5jhsw	57	42	of	of	IN
cord-260708-l9w5jhsw	57	43	any	any	DT
cord-260708-l9w5jhsw	57	44	potential	potential	JJ
cord-260708-l9w5jhsw	57	45	receptor	receptor	NN
cord-260708-l9w5jhsw	57	46	candidates	candidate	NNS
cord-260708-l9w5jhsw	57	47	.	.	.
cord-260708-l9w5jhsw	58	1	After	after	IN
cord-260708-l9w5jhsw	58	2	binding	bind	VBG
cord-260708-l9w5jhsw	58	3	to	to	IN
cord-260708-l9w5jhsw	58	4	their	-PRON-	PRP$
cord-260708-l9w5jhsw	58	5	receptor	receptor	NN
cord-260708-l9w5jhsw	58	6	,	,	,
cord-260708-l9w5jhsw	58	7	viruses	virus	NNS
cord-260708-l9w5jhsw	58	8	fuse	fuse	VBP
cord-260708-l9w5jhsw	58	9	with	with	IN
cord-260708-l9w5jhsw	58	10	the	the	DT
cord-260708-l9w5jhsw	58	11	plasma	plasma	NN
cord-260708-l9w5jhsw	58	12	membrane	membrane	NN
cord-260708-l9w5jhsw	58	13	or	or	CC
cord-260708-l9w5jhsw	58	14	internalise	internalise	VB
cord-260708-l9w5jhsw	58	15	through	through	IN
cord-260708-l9w5jhsw	58	16	one	one	CD
cord-260708-l9w5jhsw	58	17	of	of	IN
cord-260708-l9w5jhsw	58	18	several	several	JJ
cord-260708-l9w5jhsw	58	19	endocytosis	endocytosis	NN
cord-260708-l9w5jhsw	58	20	pathways	pathway	NNS
cord-260708-l9w5jhsw	58	21	to	to	TO
cord-260708-l9w5jhsw	58	22	gain	gain	VB
cord-260708-l9w5jhsw	58	23	entry	entry	NN
cord-260708-l9w5jhsw	58	24	into	into	IN
cord-260708-l9w5jhsw	58	25	the	the	DT
cord-260708-l9w5jhsw	58	26	intracellular	intracellular	JJ
cord-260708-l9w5jhsw	58	27	environment	environment	NN
cord-260708-l9w5jhsw	58	28	(	(	-LRB-
cord-260708-l9w5jhsw	58	29	reviewed	review	VBN
cord-260708-l9w5jhsw	58	30	in	in	IN
cord-260708-l9w5jhsw	58	31	refs	ref	NNS
cord-260708-l9w5jhsw	58	32	.	.	.
cord-260708-l9w5jhsw	59	1	[	[	-LRB-
cord-260708-l9w5jhsw	59	2	40	40	CD
cord-260708-l9w5jhsw	59	3	]	]	-RRB-
cord-260708-l9w5jhsw	59	4	and	and	CC
cord-260708-l9w5jhsw	59	5	[	[	-LRB-
cord-260708-l9w5jhsw	59	6	153	153	CD
cord-260708-l9w5jhsw	59	7	]	]	-RRB-
cord-260708-l9w5jhsw	59	8	)	)	-RRB-
cord-260708-l9w5jhsw	59	9	.	.	.
cord-260708-l9w5jhsw	60	1	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	60	2	entry	entry	NN
cord-260708-l9w5jhsw	60	3	is	be	VBZ
cord-260708-l9w5jhsw	60	4	dependent	dependent	JJ
cord-260708-l9w5jhsw	60	5	on	on	IN
cord-260708-l9w5jhsw	60	6	the	the	DT
cord-260708-l9w5jhsw	60	7	low	low	JJ
cord-260708-l9w5jhsw	60	8	pH	ph	NN
cord-260708-l9w5jhsw	60	9	of	of	IN
cord-260708-l9w5jhsw	60	10	the	the	DT
cord-260708-l9w5jhsw	60	11	endosomal	endosomal	NNP
cord-260708-l9w5jhsw	60	12	compartment	compartment	NN
cord-260708-l9w5jhsw	60	13	,	,	,
cord-260708-l9w5jhsw	60	14	which	which	WDT
cord-260708-l9w5jhsw	60	15	appears	appear	VBZ
cord-260708-l9w5jhsw	60	16	to	to	TO
cord-260708-l9w5jhsw	60	17	be	be	VB
cord-260708-l9w5jhsw	60	18	required	require	VBN
cord-260708-l9w5jhsw	60	19	in	in	IN
cord-260708-l9w5jhsw	60	20	the	the	DT
cord-260708-l9w5jhsw	60	21	first	first	JJ
cord-260708-l9w5jhsw	60	22	steps	step	NNS
cord-260708-l9w5jhsw	60	23	of	of	IN
cord-260708-l9w5jhsw	60	24	the	the	DT
cord-260708-l9w5jhsw	60	25	virus	virus	NN
cord-260708-l9w5jhsw	60	26	entry	entry	NN
cord-260708-l9w5jhsw	60	27	post	post	JJ
cord-260708-l9w5jhsw	60	28	-	-	NN
cord-260708-l9w5jhsw	60	29	internalisation	internalisation	JJ
cord-260708-l9w5jhsw	60	30	[	[	-LRB-
cord-260708-l9w5jhsw	60	31	74	74	CD
cord-260708-l9w5jhsw	60	32	,	,	,
cord-260708-l9w5jhsw	60	33	156	156	CD
cord-260708-l9w5jhsw	60	34	]	]	-RRB-
cord-260708-l9w5jhsw	60	35	,	,	,
cord-260708-l9w5jhsw	60	36	and	and	CC
cord-260708-l9w5jhsw	60	37	the	the	DT
cord-260708-l9w5jhsw	60	38	virus	virus	NN
cord-260708-l9w5jhsw	60	39	has	have	VBZ
cord-260708-l9w5jhsw	60	40	been	be	VBN
cord-260708-l9w5jhsw	60	41	shown	show	VBN
cord-260708-l9w5jhsw	60	42	to	to	TO
cord-260708-l9w5jhsw	60	43	use	use	VB
cord-260708-l9w5jhsw	60	44	clathrin	clathrin	NN
cord-260708-l9w5jhsw	60	45	-	-	HYPH
cord-260708-l9w5jhsw	60	46	dependent	dependent	JJ
cord-260708-l9w5jhsw	60	47	endocytosis	endocytosis	NN
cord-260708-l9w5jhsw	60	48	,	,	,
cord-260708-l9w5jhsw	60	49	while	while	IN
cord-260708-l9w5jhsw	60	50	caveolin-1	caveolin-1	NNP
cord-260708-l9w5jhsw	60	51	is	be	VBZ
cord-260708-l9w5jhsw	60	52	dispensable	dispensable	JJ
cord-260708-l9w5jhsw	60	53	for	for	IN
cord-260708-l9w5jhsw	60	54	its	-PRON-	PRP$
cord-260708-l9w5jhsw	60	55	entry	entry	NN
cord-260708-l9w5jhsw	60	56	[	[	-LRB-
cord-260708-l9w5jhsw	60	57	74	74	CD
cord-260708-l9w5jhsw	60	58	,	,	,
cord-260708-l9w5jhsw	60	59	156	156	CD
cord-260708-l9w5jhsw	60	60	]	]	-RRB-
cord-260708-l9w5jhsw	60	61	.	.	.
cord-260708-l9w5jhsw	61	1	Studies	study	NNS
cord-260708-l9w5jhsw	61	2	using	use	VBG
cord-260708-l9w5jhsw	61	3	dominant	dominant	JJ
cord-260708-l9w5jhsw	61	4	negative	negative	JJ
cord-260708-l9w5jhsw	61	5	Rab5	Rab5	NNP
cord-260708-l9w5jhsw	61	6	and	and	CC
cord-260708-l9w5jhsw	61	7	Rab7	Rab7	NNP
cord-260708-l9w5jhsw	61	8	indicate	indicate	VBP
cord-260708-l9w5jhsw	61	9	that	that	IN
cord-260708-l9w5jhsw	61	10	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	61	11	fuses	fuse	NNS
cord-260708-l9w5jhsw	61	12	with	with	IN
cord-260708-l9w5jhsw	61	13	early	early	RB
cord-260708-l9w5jhsw	61	14	,	,	,
cord-260708-l9w5jhsw	61	15	but	but	CC
cord-260708-l9w5jhsw	61	16	not	not	RB
cord-260708-l9w5jhsw	61	17	late	late	RB
cord-260708-l9w5jhsw	61	18	,	,	,
cord-260708-l9w5jhsw	61	19	endosomes	endosome	VBZ
cord-260708-l9w5jhsw	61	20	to	to	TO
cord-260708-l9w5jhsw	61	21	gain	gain	VB
cord-260708-l9w5jhsw	61	22	access	access	NN
cord-260708-l9w5jhsw	61	23	to	to	IN
cord-260708-l9w5jhsw	61	24	the	the	DT
cord-260708-l9w5jhsw	61	25	cytoplasm	cytoplasm	NN
cord-260708-l9w5jhsw	61	26	[	[	-LRB-
cord-260708-l9w5jhsw	61	27	74	74	CD
cord-260708-l9w5jhsw	61	28	]	]	-RRB-
cord-260708-l9w5jhsw	61	29	.	.	.
cord-260708-l9w5jhsw	62	1	Cholesterol	cholesterol	NN
cord-260708-l9w5jhsw	62	2	also	also	RB
cord-260708-l9w5jhsw	62	3	appears	appear	VBZ
cord-260708-l9w5jhsw	62	4	to	to	TO
cord-260708-l9w5jhsw	62	5	be	be	VB
cord-260708-l9w5jhsw	62	6	important	important	JJ
cord-260708-l9w5jhsw	62	7	for	for	IN
cord-260708-l9w5jhsw	62	8	CCHFV	cchfv	NN
cord-260708-l9w5jhsw	62	9	replication	replication	NN
cord-260708-l9w5jhsw	62	10	,	,	,
cord-260708-l9w5jhsw	62	11	especially	especially	RB
cord-260708-l9w5jhsw	62	12	at	at	IN
cord-260708-l9w5jhsw	62	13	early	early	JJ
cord-260708-l9w5jhsw	62	14	stages	stage	NNS
cord-260708-l9w5jhsw	62	15	after	after	IN
cord-260708-l9w5jhsw	62	16	binding	bind	VBG
cord-260708-l9w5jhsw	62	17	and	and	CC
cord-260708-l9w5jhsw	62	18	internalisation	internalisation	NN
cord-260708-l9w5jhsw	62	19	;	;	:
cord-260708-l9w5jhsw	62	20	it	-PRON-	PRP
cord-260708-l9w5jhsw	62	21	is	be	VBZ
cord-260708-l9w5jhsw	62	22	possible	possible	JJ
cord-260708-l9w5jhsw	62	23	that	that	IN
cord-260708-l9w5jhsw	62	24	depletion	depletion	NN
cord-260708-l9w5jhsw	62	25	of	of	IN
cord-260708-l9w5jhsw	62	26	cholesterol	cholesterol	NN
cord-260708-l9w5jhsw	62	27	from	from	IN
cord-260708-l9w5jhsw	62	28	cells	cell	NNS
cord-260708-l9w5jhsw	62	29	traps	trap	NNS
cord-260708-l9w5jhsw	62	30	viral	viral	JJ
cord-260708-l9w5jhsw	62	31	particles	particle	NNS
cord-260708-l9w5jhsw	62	32	in	in	IN
cord-260708-l9w5jhsw	62	33	endosomes	endosome	NNS
cord-260708-l9w5jhsw	62	34	[	[	-LRB-
cord-260708-l9w5jhsw	62	35	88	88	CD
cord-260708-l9w5jhsw	62	36	]	]	-RRB-
cord-260708-l9w5jhsw	62	37	or	or	CC
cord-260708-l9w5jhsw	62	38	interferes	interfere	VBZ
cord-260708-l9w5jhsw	62	39	with	with	IN
cord-260708-l9w5jhsw	62	40	clathrin	clathrin	NN
cord-260708-l9w5jhsw	62	41	-	-	HYPH
cord-260708-l9w5jhsw	62	42	mediated	mediate	VBN
cord-260708-l9w5jhsw	62	43	endocytosis	endocytosis	NN
cord-260708-l9w5jhsw	62	44	[	[	-LRB-
cord-260708-l9w5jhsw	62	45	140	140	CD
cord-260708-l9w5jhsw	62	46	]	]	-RRB-
cord-260708-l9w5jhsw	62	47	.	.	.
cord-260708-l9w5jhsw	63	1	The	the	DT
cord-260708-l9w5jhsw	63	2	internalisation	internalisation	NN
cord-260708-l9w5jhsw	63	3	of	of	IN
cord-260708-l9w5jhsw	63	4	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	63	5	virions	virion	NNS
cord-260708-l9w5jhsw	63	6	was	be	VBD
cord-260708-l9w5jhsw	63	7	shown	show	VBN
cord-260708-l9w5jhsw	63	8	to	to	TO
cord-260708-l9w5jhsw	63	9	be	be	VB
cord-260708-l9w5jhsw	63	10	dependent	dependent	JJ
cord-260708-l9w5jhsw	63	11	on	on	IN
cord-260708-l9w5jhsw	63	12	intact	intact	JJ
cord-260708-l9w5jhsw	63	13	microtubules	microtubule	NNS
cord-260708-l9w5jhsw	63	14	[	[	-LRB-
cord-260708-l9w5jhsw	63	15	155	155	CD
cord-260708-l9w5jhsw	63	16	]	]	-RRB-
cord-260708-l9w5jhsw	63	17	.	.	.
cord-260708-l9w5jhsw	64	1	Further	further	JJ
cord-260708-l9w5jhsw	64	2	investigation	investigation	NN
cord-260708-l9w5jhsw	64	3	of	of	IN
cord-260708-l9w5jhsw	64	4	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	64	5	infection	infection	NN
cord-260708-l9w5jhsw	64	6	showed	show	VBD
cord-260708-l9w5jhsw	64	7	that	that	IN
cord-260708-l9w5jhsw	64	8	disruption	disruption	NN
cord-260708-l9w5jhsw	64	9	of	of	IN
cord-260708-l9w5jhsw	64	10	the	the	DT
cord-260708-l9w5jhsw	64	11	cell	cell	NN
cord-260708-l9w5jhsw	64	12	microtubules	microtubule	NNS
cord-260708-l9w5jhsw	64	13	inhibited	inhibit	VBN
cord-260708-l9w5jhsw	64	14	viral	viral	JJ
cord-260708-l9w5jhsw	64	15	RNA	RNA	NNP
cord-260708-l9w5jhsw	64	16	replication	replication	NN
cord-260708-l9w5jhsw	64	17	[	[	-LRB-
cord-260708-l9w5jhsw	64	18	155	155	CD
cord-260708-l9w5jhsw	64	19	]	]	-RRB-
cord-260708-l9w5jhsw	64	20	,	,	,
cord-260708-l9w5jhsw	64	21	and	and	CC
cord-260708-l9w5jhsw	64	22	both	both	DT
cord-260708-l9w5jhsw	64	23	intact	intact	JJ
cord-260708-l9w5jhsw	64	24	actin	actin	NN
cord-260708-l9w5jhsw	64	25	and	and	CC
cord-260708-l9w5jhsw	64	26	microtubules	microtubule	NNS
cord-260708-l9w5jhsw	64	27	are	be	VBP
cord-260708-l9w5jhsw	64	28	essential	essential	JJ
cord-260708-l9w5jhsw	64	29	for	for	IN
cord-260708-l9w5jhsw	64	30	correct	correct	JJ
cord-260708-l9w5jhsw	64	31	distribution	distribution	NN
cord-260708-l9w5jhsw	64	32	of	of	IN
cord-260708-l9w5jhsw	64	33	the	the	DT
cord-260708-l9w5jhsw	64	34	N	n	CD
cord-260708-l9w5jhsw	64	35	protein	protein	NN
cord-260708-l9w5jhsw	64	36	to	to	IN
cord-260708-l9w5jhsw	64	37	the	the	DT
cord-260708-l9w5jhsw	64	38	perinuclear	perinuclear	NNP
cord-260708-l9w5jhsw	64	39	area	area	NN
cord-260708-l9w5jhsw	64	40	[	[	-LRB-
cord-260708-l9w5jhsw	64	41	5	5	CD
cord-260708-l9w5jhsw	64	42	,	,	,
cord-260708-l9w5jhsw	64	43	155	155	CD
cord-260708-l9w5jhsw	64	44	]	]	-RRB-
cord-260708-l9w5jhsw	64	45	.	.	.
cord-260708-l9w5jhsw	65	1	As	as	IN
cord-260708-l9w5jhsw	65	2	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	65	3	enter	enter	VBP
cord-260708-l9w5jhsw	65	4	via	via	IN
cord-260708-l9w5jhsw	65	5	endocytosis	endocytosis	NN
cord-260708-l9w5jhsw	65	6	and	and	CC
cord-260708-l9w5jhsw	65	7	bud	bud	NN
cord-260708-l9w5jhsw	65	8	in	in	IN
cord-260708-l9w5jhsw	65	9	the	the	DT
cord-260708-l9w5jhsw	65	10	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	65	11	compartment	compartment	NN
cord-260708-l9w5jhsw	65	12	,	,	,
cord-260708-l9w5jhsw	65	13	the	the	DT
cord-260708-l9w5jhsw	65	14	observation	observation	NN
cord-260708-l9w5jhsw	65	15	of	of	IN
cord-260708-l9w5jhsw	65	16	a	a	DT
cord-260708-l9w5jhsw	65	17	redistribution	redistribution	NN
cord-260708-l9w5jhsw	65	18	of	of	IN
cord-260708-l9w5jhsw	65	19	viral	viral	JJ
cord-260708-l9w5jhsw	65	20	proteins	protein	NNS
cord-260708-l9w5jhsw	65	21	and	and	CC
cord-260708-l9w5jhsw	65	22	suppression	suppression	NN
cord-260708-l9w5jhsw	65	23	of	of	IN
cord-260708-l9w5jhsw	65	24	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	65	25	assembly	assembly	NN
cord-260708-l9w5jhsw	65	26	/	/	SYM
cord-260708-l9w5jhsw	65	27	egress	egress	NN
cord-260708-l9w5jhsw	65	28	by	by	IN
cord-260708-l9w5jhsw	65	29	microtubule	microtubule	JJ
cord-260708-l9w5jhsw	65	30	modification	modification	NN
cord-260708-l9w5jhsw	65	31	(	(	-LRB-
cord-260708-l9w5jhsw	65	32	depolarisation	depolarisation	NN
cord-260708-l9w5jhsw	65	33	and	and	CC
cord-260708-l9w5jhsw	65	34	stabilisation	stabilisation	NN
cord-260708-l9w5jhsw	65	35	)	)	-RRB-
cord-260708-l9w5jhsw	65	36	[	[	-LRB-
cord-260708-l9w5jhsw	65	37	155	155	CD
cord-260708-l9w5jhsw	65	38	]	]	-RRB-
cord-260708-l9w5jhsw	65	39	is	be	VBZ
cord-260708-l9w5jhsw	65	40	not	not	RB
cord-260708-l9w5jhsw	65	41	surprising	surprising	JJ
cord-260708-l9w5jhsw	65	42	,	,	,
cord-260708-l9w5jhsw	65	43	and	and	CC
cord-260708-l9w5jhsw	65	44	this	this	DT
cord-260708-l9w5jhsw	65	45	might	may	MD
cord-260708-l9w5jhsw	65	46	be	be	VB
cord-260708-l9w5jhsw	65	47	caused	cause	VBN
cord-260708-l9w5jhsw	65	48	by	by	IN
cord-260708-l9w5jhsw	65	49	interference	interference	NN
cord-260708-l9w5jhsw	65	50	with	with	IN
cord-260708-l9w5jhsw	65	51	the	the	DT
cord-260708-l9w5jhsw	65	52	endogenous	endogenous	JJ
cord-260708-l9w5jhsw	65	53	secretory	secretory	JJ
cord-260708-l9w5jhsw	65	54	pathway	pathway	NN
cord-260708-l9w5jhsw	65	55	,	,	,
cord-260708-l9w5jhsw	65	56	which	which	WDT
cord-260708-l9w5jhsw	65	57	also	also	RB
cord-260708-l9w5jhsw	65	58	occurs	occur	VBZ
cord-260708-l9w5jhsw	65	59	along	along	IN
cord-260708-l9w5jhsw	65	60	microtubules	microtubule	NNS
cord-260708-l9w5jhsw	65	61	[	[	-LRB-
cord-260708-l9w5jhsw	65	62	101	101	CD
cord-260708-l9w5jhsw	65	63	]	]	-RRB-
cord-260708-l9w5jhsw	65	64	(	(	-LRB-
cord-260708-l9w5jhsw	65	65	reviewed	review	VBN
cord-260708-l9w5jhsw	65	66	in	in	IN
cord-260708-l9w5jhsw	65	67	ref	ref	NN
cord-260708-l9w5jhsw	65	68	.	.	.
cord-260708-l9w5jhsw	66	1	[	[	-LRB-
cord-260708-l9w5jhsw	66	2	87	87	CD
cord-260708-l9w5jhsw	66	3	]	]	-RRB-
cord-260708-l9w5jhsw	66	4	)	)	-RRB-
cord-260708-l9w5jhsw	66	5	.	.	.
cord-260708-l9w5jhsw	67	1	Disruption	disruption	NN
cord-260708-l9w5jhsw	67	2	of	of	IN
cord-260708-l9w5jhsw	67	3	actin	actin	NN
cord-260708-l9w5jhsw	67	4	filaments	filament	NNS
cord-260708-l9w5jhsw	67	5	in	in	IN
cord-260708-l9w5jhsw	67	6	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	67	7	-	-	HYPH
cord-260708-l9w5jhsw	67	8	infected	infect	VBN
cord-260708-l9w5jhsw	67	9	cells	cell	NNS
cord-260708-l9w5jhsw	67	10	also	also	RB
cord-260708-l9w5jhsw	67	11	drastically	drastically	RB
cord-260708-l9w5jhsw	67	12	reduced	reduce	VBN
cord-260708-l9w5jhsw	67	13	replication	replication	NN
cord-260708-l9w5jhsw	67	14	of	of	IN
cord-260708-l9w5jhsw	67	15	the	the	DT
cord-260708-l9w5jhsw	67	16	virus	virus	NN
cord-260708-l9w5jhsw	67	17	[	[	-LRB-
cord-260708-l9w5jhsw	67	18	5	5	CD
cord-260708-l9w5jhsw	67	19	]	]	-RRB-
cord-260708-l9w5jhsw	67	20	.	.	.
cord-260708-l9w5jhsw	68	1	While	while	IN
cord-260708-l9w5jhsw	68	2	the	the	DT
cord-260708-l9w5jhsw	68	3	N	N	NNP
cord-260708-l9w5jhsw	68	4	protein	protein	NN
cord-260708-l9w5jhsw	68	5	is	be	VBZ
cord-260708-l9w5jhsw	68	6	often	often	RB
cord-260708-l9w5jhsw	68	7	located	locate	VBN
cord-260708-l9w5jhsw	68	8	in	in	IN
cord-260708-l9w5jhsw	68	9	close	close	JJ
cord-260708-l9w5jhsw	68	10	proximity	proximity	NN
cord-260708-l9w5jhsw	68	11	to	to	IN
cord-260708-l9w5jhsw	68	12	the	the	DT
cord-260708-l9w5jhsw	68	13	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	68	14	apparatus	apparatus	NN
cord-260708-l9w5jhsw	68	15	,	,	,
cord-260708-l9w5jhsw	68	16	where	where	WRB
cord-260708-l9w5jhsw	68	17	generation	generation	NN
cord-260708-l9w5jhsw	68	18	of	of	IN
cord-260708-l9w5jhsw	68	19	new	new	JJ
cord-260708-l9w5jhsw	68	20	viral	viral	JJ
cord-260708-l9w5jhsw	68	21	particles	particle	NNS
cord-260708-l9w5jhsw	68	22	occurs	occur	VBZ
cord-260708-l9w5jhsw	68	23	[	[	-LRB-
cord-260708-l9w5jhsw	68	24	16	16	CD
cord-260708-l9w5jhsw	68	25	]	]	-RRB-
cord-260708-l9w5jhsw	68	26	,	,	,
cord-260708-l9w5jhsw	68	27	N	N	NNP
cord-260708-l9w5jhsw	68	28	does	do	VBZ
cord-260708-l9w5jhsw	68	29	not	not	RB
cord-260708-l9w5jhsw	68	30	interact	interact	VB
cord-260708-l9w5jhsw	68	31	directly	directly	RB
cord-260708-l9w5jhsw	68	32	with	with	IN
cord-260708-l9w5jhsw	68	33	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	68	34	membranes	membrane	NNS
cord-260708-l9w5jhsw	68	35	[	[	-LRB-
cord-260708-l9w5jhsw	68	36	5	5	CD
cord-260708-l9w5jhsw	68	37	,	,	,
cord-260708-l9w5jhsw	68	38	134	134	CD
cord-260708-l9w5jhsw	68	39	]	]	-RRB-
cord-260708-l9w5jhsw	68	40	.	.	.
cord-260708-l9w5jhsw	69	1	The	the	DT
cord-260708-l9w5jhsw	69	2	N	N	NNP
cord-260708-l9w5jhsw	69	3	protein	protein	NN
cord-260708-l9w5jhsw	69	4	appears	appear	VBZ
cord-260708-l9w5jhsw	69	5	to	to	TO
cord-260708-l9w5jhsw	69	6	interact	interact	VB
cord-260708-l9w5jhsw	69	7	with	with	IN
cord-260708-l9w5jhsw	69	8	the	the	DT
cord-260708-l9w5jhsw	69	9	L	L	NNP
cord-260708-l9w5jhsw	69	10	protein	protein	NN
cord-260708-l9w5jhsw	69	11	,	,	,
cord-260708-l9w5jhsw	69	12	even	even	RB
cord-260708-l9w5jhsw	69	13	in	in	IN
cord-260708-l9w5jhsw	69	14	the	the	DT
cord-260708-l9w5jhsw	69	15	absence	absence	NN
cord-260708-l9w5jhsw	69	16	of	of	IN
cord-260708-l9w5jhsw	69	17	viral	viral	JJ
cord-260708-l9w5jhsw	69	18	RNA	RNA	NNP
cord-260708-l9w5jhsw	69	19	,	,	,
cord-260708-l9w5jhsw	69	20	as	as	IN
cord-260708-l9w5jhsw	69	21	expressed	express	VBN
cord-260708-l9w5jhsw	69	22	N	n	CD
cord-260708-l9w5jhsw	69	23	protein	protein	NN
cord-260708-l9w5jhsw	69	24	seems	seem	VBZ
cord-260708-l9w5jhsw	69	25	to	to	TO
cord-260708-l9w5jhsw	69	26	redistribute	redistribute	VB
cord-260708-l9w5jhsw	69	27	most	most	JJS
cord-260708-l9w5jhsw	69	28	of	of	IN
cord-260708-l9w5jhsw	69	29	the	the	DT
cord-260708-l9w5jhsw	69	30	L	L	NNP
cord-260708-l9w5jhsw	69	31	protein	protein	NN
cord-260708-l9w5jhsw	69	32	into	into	IN
cord-260708-l9w5jhsw	69	33	the	the	DT
cord-260708-l9w5jhsw	69	34	perinuclear	perinuclear	NNP
cord-260708-l9w5jhsw	69	35	area	area	NN
cord-260708-l9w5jhsw	69	36	containing	contain	VBG
cord-260708-l9w5jhsw	69	37	N	n	CD
cord-260708-l9w5jhsw	69	38	in	in	IN
cord-260708-l9w5jhsw	69	39	transfected	transfecte	VBN
cord-260708-l9w5jhsw	69	40	cells	cell	NNS
cord-260708-l9w5jhsw	69	41	[	[	-LRB-
cord-260708-l9w5jhsw	69	42	16	16	CD
cord-260708-l9w5jhsw	69	43	]	]	-RRB-
cord-260708-l9w5jhsw	69	44	.	.	.
cord-260708-l9w5jhsw	70	1	The	the	DT
cord-260708-l9w5jhsw	70	2	N	N	NNP
cord-260708-l9w5jhsw	70	3	protein	protein	NN
cord-260708-l9w5jhsw	70	4	of	of	IN
cord-260708-l9w5jhsw	70	5	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	70	6	,	,	,
cord-260708-l9w5jhsw	70	7	at	at	IN
cord-260708-l9w5jhsw	70	8	approximately	approximately	RB
cord-260708-l9w5jhsw	70	9	53	53	CD
cord-260708-l9w5jhsw	70	10	kDa	kDa	NNS
cord-260708-l9w5jhsw	70	11	,	,	,
cord-260708-l9w5jhsw	70	12	is	be	VBZ
cord-260708-l9w5jhsw	70	13	almost	almost	RB
cord-260708-l9w5jhsw	70	14	twice	twice	RB
cord-260708-l9w5jhsw	70	15	of	of	IN
cord-260708-l9w5jhsw	70	16	size	size	NN
cord-260708-l9w5jhsw	70	17	of	of	IN
cord-260708-l9w5jhsw	70	18	the	the	DT
cord-260708-l9w5jhsw	70	19	N	n	CD
cord-260708-l9w5jhsw	70	20	proteins	protein	NNS
cord-260708-l9w5jhsw	70	21	of	of	IN
cord-260708-l9w5jhsw	70	22	other	other	JJ
cord-260708-l9w5jhsw	70	23	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	70	24	,	,	,
cord-260708-l9w5jhsw	70	25	with	with	IN
cord-260708-l9w5jhsw	70	26	the	the	DT
cord-260708-l9w5jhsw	70	27	exception	exception	NN
cord-260708-l9w5jhsw	70	28	of	of	IN
cord-260708-l9w5jhsw	70	29	those	those	DT
cord-260708-l9w5jhsw	70	30	of	of	IN
cord-260708-l9w5jhsw	70	31	hantaviruses	hantaviruses	NNP
cord-260708-l9w5jhsw	70	32	,	,	,
cord-260708-l9w5jhsw	70	33	which	which	WDT
cord-260708-l9w5jhsw	70	34	,	,	,
cord-260708-l9w5jhsw	70	35	at	at	IN
cord-260708-l9w5jhsw	70	36	approx	approx	NN
cord-260708-l9w5jhsw	70	37	.	.	.
cord-260708-l9w5jhsw	71	1	48	48	CD
cord-260708-l9w5jhsw	71	2	kDa	kDa	NNS
cord-260708-l9w5jhsw	71	3	,	,	,
cord-260708-l9w5jhsw	71	4	are	be	VBP
cord-260708-l9w5jhsw	71	5	similar	similar	JJ
cord-260708-l9w5jhsw	71	6	in	in	IN
cord-260708-l9w5jhsw	71	7	size	size	NN
cord-260708-l9w5jhsw	71	8	[	[	-LRB-
cord-260708-l9w5jhsw	71	9	39	39	CD
cord-260708-l9w5jhsw	71	10	,	,	,
cord-260708-l9w5jhsw	71	11	110	110	CD
cord-260708-l9w5jhsw	71	12	]	]	-RRB-
cord-260708-l9w5jhsw	71	13	.	.	.
cord-260708-l9w5jhsw	72	1	The	the	DT
cord-260708-l9w5jhsw	72	2	N	N	NNP
cord-260708-l9w5jhsw	72	3	protein	protein	NN
cord-260708-l9w5jhsw	72	4	is	be	VBZ
cord-260708-l9w5jhsw	72	5	the	the	DT
cord-260708-l9w5jhsw	72	6	most	most	RBS
cord-260708-l9w5jhsw	72	7	abundant	abundant	JJ
cord-260708-l9w5jhsw	72	8	protein	protein	NN
cord-260708-l9w5jhsw	72	9	in	in	IN
cord-260708-l9w5jhsw	72	10	the	the	DT
cord-260708-l9w5jhsw	72	11	virion	virion	NN
cord-260708-l9w5jhsw	72	12	and	and	CC
cord-260708-l9w5jhsw	72	13	encapsidates	encapsidate	NNS
cord-260708-l9w5jhsw	72	14	newly	newly	RB
cord-260708-l9w5jhsw	72	15	synthesised	synthesise	VBN
cord-260708-l9w5jhsw	72	16	vRNA	vrna	RP
cord-260708-l9w5jhsw	72	17	and	and	CC
cord-260708-l9w5jhsw	72	18	cRNA	cRNA	NNS
cord-260708-l9w5jhsw	72	19	;	;	:
cord-260708-l9w5jhsw	72	20	this	this	DT
cord-260708-l9w5jhsw	72	21	process	process	NN
cord-260708-l9w5jhsw	72	22	is	be	VBZ
cord-260708-l9w5jhsw	72	23	necessary	necessary	JJ
cord-260708-l9w5jhsw	72	24	for	for	IN
cord-260708-l9w5jhsw	72	25	completion	completion	NN
cord-260708-l9w5jhsw	72	26	of	of	IN
cord-260708-l9w5jhsw	72	27	the	the	DT
cord-260708-l9w5jhsw	72	28	replication	replication	NN
cord-260708-l9w5jhsw	72	29	cycle	cycle	NN
cord-260708-l9w5jhsw	72	30	and	and	CC
cord-260708-l9w5jhsw	72	31	packaging	packaging	NN
cord-260708-l9w5jhsw	72	32	of	of	IN
cord-260708-l9w5jhsw	72	33	the	the	DT
cord-260708-l9w5jhsw	72	34	genome	genome	NN
cord-260708-l9w5jhsw	72	35	into	into	IN
cord-260708-l9w5jhsw	72	36	virions	virion	NNS
cord-260708-l9w5jhsw	72	37	[	[	-LRB-
cord-260708-l9w5jhsw	72	38	16	16	CD
cord-260708-l9w5jhsw	72	39	,	,	,
cord-260708-l9w5jhsw	72	40	65	65	CD
cord-260708-l9w5jhsw	72	41	,	,	,
cord-260708-l9w5jhsw	72	42	100	100	CD
cord-260708-l9w5jhsw	72	43	]	]	-RRB-
cord-260708-l9w5jhsw	72	44	.	.	.
cord-260708-l9w5jhsw	73	1	Viruses	virus	NNS
cord-260708-l9w5jhsw	73	2	of	of	IN
cord-260708-l9w5jhsw	73	3	different	different	JJ
cord-260708-l9w5jhsw	73	4	genera	genus	NNS
cord-260708-l9w5jhsw	73	5	in	in	IN
cord-260708-l9w5jhsw	73	6	the	the	DT
cord-260708-l9w5jhsw	73	7	family	family	NN
cord-260708-l9w5jhsw	73	8	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	73	9	appear	appear	VB
cord-260708-l9w5jhsw	73	10	to	to	TO
cord-260708-l9w5jhsw	73	11	adopt	adopt	VB
cord-260708-l9w5jhsw	73	12	different	different	JJ
cord-260708-l9w5jhsw	73	13	mechanisms	mechanism	NNS
cord-260708-l9w5jhsw	73	14	of	of	IN
cord-260708-l9w5jhsw	73	15	RNA	RNA	NNP
cord-260708-l9w5jhsw	73	16	encapsidation	encapsidation	NN
cord-260708-l9w5jhsw	73	17	,	,	,
cord-260708-l9w5jhsw	73	18	e.g.	e.g.	RB
cord-260708-l9w5jhsw	73	19	some	some	DT
cord-260708-l9w5jhsw	73	20	bunyavirus	bunyavirus	NNP
cord-260708-l9w5jhsw	73	21	N	n	CD
cord-260708-l9w5jhsw	73	22	proteins	protein	NNS
cord-260708-l9w5jhsw	73	23	recognise	recognise	VBP
cord-260708-l9w5jhsw	73	24	generic	generic	JJ
cord-260708-l9w5jhsw	73	25	ssRNA	ssrna	NN
cord-260708-l9w5jhsw	73	26	,	,	,
cord-260708-l9w5jhsw	73	27	while	while	IN
cord-260708-l9w5jhsw	73	28	others	other	NNS
cord-260708-l9w5jhsw	73	29	recognise	recognise	VBP
cord-260708-l9w5jhsw	73	30	specific	specific	JJ
cord-260708-l9w5jhsw	73	31	structures	structure	NNS
cord-260708-l9w5jhsw	73	32	in	in	IN
cord-260708-l9w5jhsw	73	33	the	the	DT
cord-260708-l9w5jhsw	73	34	vRNA	vRNA	JJS
cord-260708-l9w5jhsw	73	35	[	[	-LRB-
cord-260708-l9w5jhsw	73	36	110	110	CD
cord-260708-l9w5jhsw	73	37	,	,	,
cord-260708-l9w5jhsw	73	38	120	120	CD
cord-260708-l9w5jhsw	73	39	,	,	,
cord-260708-l9w5jhsw	73	40	135	135	CD
cord-260708-l9w5jhsw	73	41	,	,	,
cord-260708-l9w5jhsw	73	42	137	137	CD
cord-260708-l9w5jhsw	73	43	,	,	,
cord-260708-l9w5jhsw	73	44	150	150	CD
cord-260708-l9w5jhsw	73	45	]	]	-RRB-
cord-260708-l9w5jhsw	73	46	.	.	.
cord-260708-l9w5jhsw	74	1	There	there	EX
cord-260708-l9w5jhsw	74	2	is	be	VBZ
cord-260708-l9w5jhsw	74	3	a	a	DT
cord-260708-l9w5jhsw	74	4	need	need	NN
cord-260708-l9w5jhsw	74	5	to	to	TO
cord-260708-l9w5jhsw	74	6	understand	understand	VB
cord-260708-l9w5jhsw	74	7	the	the	DT
cord-260708-l9w5jhsw	74	8	mechanism	mechanism	NN
cord-260708-l9w5jhsw	74	9	by	by	IN
cord-260708-l9w5jhsw	74	10	which	which	WDT
cord-260708-l9w5jhsw	74	11	nairoviruses	nairoviruses	NNP
cord-260708-l9w5jhsw	74	12	encapsidate	encapsidate	NNP
cord-260708-l9w5jhsw	74	13	genomic	genomic	NNP
cord-260708-l9w5jhsw	74	14	and	and	CC
cord-260708-l9w5jhsw	74	15	antigenomic	antigenomic	NNP
cord-260708-l9w5jhsw	74	16	RNA	RNA	NNP
cord-260708-l9w5jhsw	74	17	;	;	,
cord-260708-l9w5jhsw	74	18	inhibition	inhibition	NN
cord-260708-l9w5jhsw	74	19	of	of	IN
cord-260708-l9w5jhsw	74	20	vRNA	vrna	JJ
cord-260708-l9w5jhsw	74	21	encapsidation	encapsidation	NN
cord-260708-l9w5jhsw	74	22	could	could	MD
cord-260708-l9w5jhsw	74	23	be	be	VB
cord-260708-l9w5jhsw	74	24	a	a	DT
cord-260708-l9w5jhsw	74	25	target	target	NN
cord-260708-l9w5jhsw	74	26	for	for	IN
cord-260708-l9w5jhsw	74	27	potential	potential	JJ
cord-260708-l9w5jhsw	74	28	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	74	29	drugs	drug	NNS
cord-260708-l9w5jhsw	74	30	,	,	,
cord-260708-l9w5jhsw	74	31	e.g.	e.g.	RB
cord-260708-l9w5jhsw	74	32	,	,	,
cord-260708-l9w5jhsw	74	33	using	use	VBG
cord-260708-l9w5jhsw	74	34	an	an	DT
cord-260708-l9w5jhsw	74	35	RNA	RNA	NNP
cord-260708-l9w5jhsw	74	36	decoy	decoy	NN
cord-260708-l9w5jhsw	74	37	to	to	TO
cord-260708-l9w5jhsw	74	38	bind	bind	VB
cord-260708-l9w5jhsw	74	39	the	the	DT
cord-260708-l9w5jhsw	74	40	viral	viral	JJ
cord-260708-l9w5jhsw	74	41	N	n	CD
cord-260708-l9w5jhsw	74	42	protein	protein	NN
cord-260708-l9w5jhsw	74	43	,	,	,
cord-260708-l9w5jhsw	74	44	as	as	IN
cord-260708-l9w5jhsw	74	45	has	have	VBZ
cord-260708-l9w5jhsw	74	46	been	be	VBN
cord-260708-l9w5jhsw	74	47	suggested	suggest	VBN
cord-260708-l9w5jhsw	74	48	as	as	IN
cord-260708-l9w5jhsw	74	49	an	an	DT
cord-260708-l9w5jhsw	74	50	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	74	51	treatment	treatment	NN
cord-260708-l9w5jhsw	74	52	for	for	IN
cord-260708-l9w5jhsw	74	53	hepatitis	hepatitis	NN
cord-260708-l9w5jhsw	74	54	B	B	NNP
cord-260708-l9w5jhsw	74	55	virus	virus	NN
cord-260708-l9w5jhsw	74	56	(	(	-LRB-
cord-260708-l9w5jhsw	74	57	HBV	HBV	NNP
cord-260708-l9w5jhsw	74	58	)	)	-RRB-
cord-260708-l9w5jhsw	75	1	[	[	-LRB-
cord-260708-l9w5jhsw	75	2	62	62	CD
cord-260708-l9w5jhsw	75	3	]	]	-RRB-
cord-260708-l9w5jhsw	75	4	,	,	,
cord-260708-l9w5jhsw	75	5	or	or	CC
cord-260708-l9w5jhsw	75	6	selecting	select	VBG
cord-260708-l9w5jhsw	75	7	RNA	rna	NN
cord-260708-l9w5jhsw	75	8	-	-	HYPH
cord-260708-l9w5jhsw	75	9	binding	bind	VBG
cord-260708-l9w5jhsw	75	10	proteins	protein	NNS
cord-260708-l9w5jhsw	75	11	that	that	WDT
cord-260708-l9w5jhsw	75	12	target	target	VBP
cord-260708-l9w5jhsw	75	13	specific	specific	JJ
cord-260708-l9w5jhsw	75	14	packaging	packaging	NN
cord-260708-l9w5jhsw	75	15	sequences	sequence	NNS
cord-260708-l9w5jhsw	75	16	in	in	IN
cord-260708-l9w5jhsw	75	17	the	the	DT
cord-260708-l9w5jhsw	75	18	viral	viral	JJ
cord-260708-l9w5jhsw	75	19	genome	genome	NN
cord-260708-l9w5jhsw	75	20	[	[	-LRB-
cord-260708-l9w5jhsw	75	21	193	193	CD
cord-260708-l9w5jhsw	75	22	]	]	-RRB-
cord-260708-l9w5jhsw	75	23	.	.	.
cord-260708-l9w5jhsw	76	1	The	the	DT
cord-260708-l9w5jhsw	76	2	recently	recently	RB
cord-260708-l9w5jhsw	76	3	determined	determine	VBN
cord-260708-l9w5jhsw	76	4	crystal	crystal	NN
cord-260708-l9w5jhsw	76	5	structure	structure	NN
cord-260708-l9w5jhsw	76	6	of	of	IN
cord-260708-l9w5jhsw	76	7	the	the	DT
cord-260708-l9w5jhsw	76	8	N	N	NNP
cord-260708-l9w5jhsw	76	9	protein	protein	NN
cord-260708-l9w5jhsw	76	10	of	of	IN
cord-260708-l9w5jhsw	76	11	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	76	12	shows	show	VBZ
cord-260708-l9w5jhsw	76	13	that	that	IN
cord-260708-l9w5jhsw	76	14	it	-PRON-	PRP
cord-260708-l9w5jhsw	76	15	is	be	VBZ
cord-260708-l9w5jhsw	76	16	built	build	VBN
cord-260708-l9w5jhsw	76	17	from	from	IN
cord-260708-l9w5jhsw	76	18	two	two	CD
cord-260708-l9w5jhsw	76	19	major	major	JJ
cord-260708-l9w5jhsw	76	20	domains	domain	NNS
cord-260708-l9w5jhsw	76	21	:	:	:
cord-260708-l9w5jhsw	76	22	a	a	DT
cord-260708-l9w5jhsw	76	23	globular	globular	JJ
cord-260708-l9w5jhsw	76	24	head	head	NN
cord-260708-l9w5jhsw	76	25	and	and	CC
cord-260708-l9w5jhsw	76	26	an	an	DT
cord-260708-l9w5jhsw	76	27	extended	extended	JJ
cord-260708-l9w5jhsw	76	28	stalk	stalk	NN
cord-260708-l9w5jhsw	76	29	[	[	-LRB-
cord-260708-l9w5jhsw	76	30	31	31	CD
cord-260708-l9w5jhsw	76	31	,	,	,
cord-260708-l9w5jhsw	76	32	77	77	CD
cord-260708-l9w5jhsw	76	33	,	,	,
cord-260708-l9w5jhsw	76	34	174	174	CD
cord-260708-l9w5jhsw	76	35	]	]	-RRB-
cord-260708-l9w5jhsw	76	36	.	.	.
cord-260708-l9w5jhsw	77	1	The	the	DT
cord-260708-l9w5jhsw	77	2	globular	globular	JJ
cord-260708-l9w5jhsw	77	3	domain	domain	NN
cord-260708-l9w5jhsw	77	4	is	be	VBZ
cord-260708-l9w5jhsw	77	5	the	the	DT
cord-260708-l9w5jhsw	77	6	larger	large	JJR
cord-260708-l9w5jhsw	77	7	and	and	CC
cord-260708-l9w5jhsw	77	8	is	be	VBZ
cord-260708-l9w5jhsw	77	9	formed	form	VBN
cord-260708-l9w5jhsw	77	10	from	from	IN
cord-260708-l9w5jhsw	77	11	both	both	DT
cord-260708-l9w5jhsw	77	12	N	n	CD
cord-260708-l9w5jhsw	77	13	-	-	HYPH
cord-260708-l9w5jhsw	77	14	terminal	terminal	NN
cord-260708-l9w5jhsw	77	15	and	and	CC
cord-260708-l9w5jhsw	77	16	C	c	NN
cord-260708-l9w5jhsw	77	17	-	-	HYPH
cord-260708-l9w5jhsw	77	18	terminal	terminal	NN
cord-260708-l9w5jhsw	77	19	helices	helix	NNS
cord-260708-l9w5jhsw	77	20	,	,	,
cord-260708-l9w5jhsw	77	21	while	while	IN
cord-260708-l9w5jhsw	77	22	the	the	DT
cord-260708-l9w5jhsw	77	23	stalk	stalk	NN
cord-260708-l9w5jhsw	77	24	domain	domain	NN
cord-260708-l9w5jhsw	77	25	is	be	VBZ
cord-260708-l9w5jhsw	77	26	formed	form	VBN
cord-260708-l9w5jhsw	77	27	by	by	IN
cord-260708-l9w5jhsw	77	28	a	a	DT
cord-260708-l9w5jhsw	77	29	group	group	NN
cord-260708-l9w5jhsw	77	30	of	of	IN
cord-260708-l9w5jhsw	77	31	internal	internal	JJ
cord-260708-l9w5jhsw	77	32	helices	helix	NNS
cord-260708-l9w5jhsw	77	33	(	(	-LRB-
cord-260708-l9w5jhsw	77	34	the	the	DT
cord-260708-l9w5jhsw	77	35	exact	exact	JJ
cord-260708-l9w5jhsw	77	36	numbering	numbering	NN
cord-260708-l9w5jhsw	77	37	of	of	IN
cord-260708-l9w5jhsw	77	38	the	the	DT
cord-260708-l9w5jhsw	77	39	helices	helix	NNS
cord-260708-l9w5jhsw	77	40	varies	vary	VBZ
cord-260708-l9w5jhsw	77	41	between	between	IN
cord-260708-l9w5jhsw	77	42	the	the	DT
cord-260708-l9w5jhsw	77	43	several	several	JJ
cord-260708-l9w5jhsw	77	44	papers	paper	NNS
cord-260708-l9w5jhsw	77	45	publishing	publish	VBG
cord-260708-l9w5jhsw	77	46	the	the	DT
cord-260708-l9w5jhsw	77	47	structure	structure	NN
cord-260708-l9w5jhsw	77	48	of	of	IN
cord-260708-l9w5jhsw	77	49	this	this	DT
cord-260708-l9w5jhsw	77	50	protein	protein	NN
cord-260708-l9w5jhsw	77	51	)	)	-RRB-
cord-260708-l9w5jhsw	77	52	.	.	.
cord-260708-l9w5jhsw	78	1	Three	three	CD
cord-260708-l9w5jhsw	78	2	potential	potential	JJ
cord-260708-l9w5jhsw	78	3	RNA	rna	NN
cord-260708-l9w5jhsw	78	4	-	-	HYPH
cord-260708-l9w5jhsw	78	5	binding	bind	VBG
cord-260708-l9w5jhsw	78	6	regions	region	NNS
cord-260708-l9w5jhsw	78	7	were	be	VBD
cord-260708-l9w5jhsw	78	8	identified	identify	VBN
cord-260708-l9w5jhsw	78	9	in	in	IN
cord-260708-l9w5jhsw	78	10	the	the	DT
cord-260708-l9w5jhsw	78	11	N	N	NNP
cord-260708-l9w5jhsw	78	12	protein	protein	NN
cord-260708-l9w5jhsw	78	13	structure	structure	NN
cord-260708-l9w5jhsw	78	14	.	.	.
cord-260708-l9w5jhsw	79	1	Two	two	CD
cord-260708-l9w5jhsw	79	2	positively	positively	RB
cord-260708-l9w5jhsw	79	3	charged	charge	VBN
cord-260708-l9w5jhsw	79	4	grooves	groove	NNS
cord-260708-l9w5jhsw	79	5	are	be	VBP
cord-260708-l9w5jhsw	79	6	located	locate	VBN
cord-260708-l9w5jhsw	79	7	in	in	IN
cord-260708-l9w5jhsw	79	8	the	the	DT
cord-260708-l9w5jhsw	79	9	globular	globular	JJ
cord-260708-l9w5jhsw	79	10	domain	domain	NN
cord-260708-l9w5jhsw	79	11	:	:	:
cord-260708-l9w5jhsw	79	12	the	the	DT
cord-260708-l9w5jhsw	79	13	smaller	small	JJR
cord-260708-l9w5jhsw	79	14	one	one	NN
cord-260708-l9w5jhsw	79	15	is	be	VBZ
cord-260708-l9w5jhsw	79	16	under	under	IN
cord-260708-l9w5jhsw	79	17	the	the	DT
cord-260708-l9w5jhsw	79	18	stalk	stalk	NN
cord-260708-l9w5jhsw	79	19	domain	domain	NN
cord-260708-l9w5jhsw	79	20	,	,	,
cord-260708-l9w5jhsw	79	21	and	and	CC
cord-260708-l9w5jhsw	79	22	the	the	DT
cord-260708-l9w5jhsw	79	23	larger	large	JJR
cord-260708-l9w5jhsw	79	24	one	one	NN
cord-260708-l9w5jhsw	79	25	is	be	VBZ
cord-260708-l9w5jhsw	79	26	in	in	IN
cord-260708-l9w5jhsw	79	27	the	the	DT
cord-260708-l9w5jhsw	79	28	opposite	opposite	JJ
cord-260708-l9w5jhsw	79	29	site	site	NN
cord-260708-l9w5jhsw	79	30	of	of	IN
cord-260708-l9w5jhsw	79	31	the	the	DT
cord-260708-l9w5jhsw	79	32	globular	globular	JJ
cord-260708-l9w5jhsw	79	33	domain	domain	NN
cord-260708-l9w5jhsw	79	34	.	.	.
cord-260708-l9w5jhsw	80	1	The	the	DT
cord-260708-l9w5jhsw	80	2	third	third	JJ
cord-260708-l9w5jhsw	80	3	positive	positive	JJ
cord-260708-l9w5jhsw	80	4	groove	groove	NN
cord-260708-l9w5jhsw	80	5	is	be	VBZ
cord-260708-l9w5jhsw	80	6	located	locate	VBN
cord-260708-l9w5jhsw	80	7	in	in	IN
cord-260708-l9w5jhsw	80	8	the	the	DT
cord-260708-l9w5jhsw	80	9	stalk	stalk	NN
cord-260708-l9w5jhsw	80	10	domain	domain	NN
cord-260708-l9w5jhsw	80	11	.	.	.
cord-260708-l9w5jhsw	81	1	The	the	DT
cord-260708-l9w5jhsw	81	2	positively	positively	RB
cord-260708-l9w5jhsw	81	3	charged	charge	VBN
cord-260708-l9w5jhsw	81	4	residues	residue	NNS
cord-260708-l9w5jhsw	81	5	forming	form	VBG
cord-260708-l9w5jhsw	81	6	the	the	DT
cord-260708-l9w5jhsw	81	7	RNA	RNA	NNP
cord-260708-l9w5jhsw	81	8	-	-	HYPH
cord-260708-l9w5jhsw	81	9	binding	bind	VBG
cord-260708-l9w5jhsw	81	10	site	site	NN
cord-260708-l9w5jhsw	81	11	appear	appear	VBP
cord-260708-l9w5jhsw	81	12	to	to	TO
cord-260708-l9w5jhsw	81	13	be	be	VB
cord-260708-l9w5jhsw	81	14	well	well	RB
cord-260708-l9w5jhsw	81	15	conserved	conserve	VBN
cord-260708-l9w5jhsw	81	16	across	across	IN
cord-260708-l9w5jhsw	81	17	the	the	DT
cord-260708-l9w5jhsw	81	18	genus	genus	NN
cord-260708-l9w5jhsw	81	19	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	81	20	,	,	,
cord-260708-l9w5jhsw	81	21	and	and	CC
cord-260708-l9w5jhsw	81	22	several	several	JJ
cord-260708-l9w5jhsw	81	23	residues	residue	NNS
cord-260708-l9w5jhsw	81	24	were	be	VBD
cord-260708-l9w5jhsw	81	25	identified	identify	VBN
cord-260708-l9w5jhsw	81	26	as	as	IN
cord-260708-l9w5jhsw	81	27	crucial	crucial	JJ
cord-260708-l9w5jhsw	81	28	for	for	IN
cord-260708-l9w5jhsw	81	29	RNA	rna	NN
cord-260708-l9w5jhsw	81	30	binding	binding	NN
cord-260708-l9w5jhsw	81	31	and	and	CC
cord-260708-l9w5jhsw	81	32	virus	virus	NN
cord-260708-l9w5jhsw	81	33	replication	replication	NN
cord-260708-l9w5jhsw	81	34	,	,	,
cord-260708-l9w5jhsw	81	35	e.g.	e.g.	RB
cord-260708-l9w5jhsw	81	36	,	,	,
cord-260708-l9w5jhsw	81	37	K132	K132	''
cord-260708-l9w5jhsw	81	38	and	and	CC
cord-260708-l9w5jhsw	81	39	Q300	Q300	NNPS
cord-260708-l9w5jhsw	81	40	in	in	IN
cord-260708-l9w5jhsw	81	41	the	the	DT
cord-260708-l9w5jhsw	81	42	smaller	small	JJR
cord-260708-l9w5jhsw	81	43	groove	groove	NN
cord-260708-l9w5jhsw	81	44	and	and	CC
cord-260708-l9w5jhsw	81	45	K411	k411	XX
cord-260708-l9w5jhsw	81	46	and	and	CC
cord-260708-l9w5jhsw	81	47	H456	h456	NN
cord-260708-l9w5jhsw	81	48	in	in	IN
cord-260708-l9w5jhsw	81	49	the	the	DT
cord-260708-l9w5jhsw	81	50	larger	large	JJR
cord-260708-l9w5jhsw	81	51	groove	groove	NN
cord-260708-l9w5jhsw	81	52	of	of	IN
cord-260708-l9w5jhsw	81	53	the	the	DT
cord-260708-l9w5jhsw	81	54	head	head	NN
cord-260708-l9w5jhsw	81	55	domain	domain	NN
cord-260708-l9w5jhsw	81	56	[	[	-LRB-
cord-260708-l9w5jhsw	81	57	31	31	CD
cord-260708-l9w5jhsw	81	58	,	,	,
cord-260708-l9w5jhsw	81	59	77	77	CD
cord-260708-l9w5jhsw	81	60	]	]	-RRB-
cord-260708-l9w5jhsw	81	61	.	.	.
cord-260708-l9w5jhsw	82	1	The	the	DT
cord-260708-l9w5jhsw	82	2	N	n	CD
cord-260708-l9w5jhsw	82	3	protein	protein	NN
cord-260708-l9w5jhsw	82	4	of	of	IN
cord-260708-l9w5jhsw	82	5	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	82	6	was	be	VBD
cord-260708-l9w5jhsw	82	7	also	also	RB
cord-260708-l9w5jhsw	82	8	crystallised	crystallise	VBN
cord-260708-l9w5jhsw	82	9	as	as	IN
cord-260708-l9w5jhsw	82	10	a	a	DT
cord-260708-l9w5jhsw	82	11	linear	linear	JJ
cord-260708-l9w5jhsw	82	12	oligomer	oligomer	NN
cord-260708-l9w5jhsw	82	13	,	,	,
cord-260708-l9w5jhsw	82	14	where	where	WRB
cord-260708-l9w5jhsw	82	15	three	three	CD
cord-260708-l9w5jhsw	82	16	monomeric	monomeric	JJ
cord-260708-l9w5jhsw	82	17	N	N	NNP
cord-260708-l9w5jhsw	82	18	subunits	subunit	NNS
cord-260708-l9w5jhsw	82	19	were	be	VBD
cord-260708-l9w5jhsw	82	20	organised	organise	VBN
cord-260708-l9w5jhsw	82	21	in	in	IN
cord-260708-l9w5jhsw	82	22	head	head	NN
cord-260708-l9w5jhsw	82	23	-	-	HYPH
cord-260708-l9w5jhsw	82	24	to	to	IN
cord-260708-l9w5jhsw	82	25	-	-	HYPH
cord-260708-l9w5jhsw	82	26	tail	tail	NN
cord-260708-l9w5jhsw	82	27	manner	manner	NN
cord-260708-l9w5jhsw	82	28	,	,	,
cord-260708-l9w5jhsw	82	29	with	with	IN
cord-260708-l9w5jhsw	82	30	the	the	DT
cord-260708-l9w5jhsw	82	31	stalk	stalk	NN
cord-260708-l9w5jhsw	82	32	domain	domain	NN
cord-260708-l9w5jhsw	82	33	of	of	IN
cord-260708-l9w5jhsw	82	34	one	one	CD
cord-260708-l9w5jhsw	82	35	monomer	monomer	NN
cord-260708-l9w5jhsw	82	36	interacting	interact	VBG
cord-260708-l9w5jhsw	82	37	with	with	IN
cord-260708-l9w5jhsw	82	38	an	an	DT
cord-260708-l9w5jhsw	82	39	oligomeric	oligomeric	JJ
cord-260708-l9w5jhsw	82	40	groove	groove	NN
cord-260708-l9w5jhsw	82	41	located	locate	VBN
cord-260708-l9w5jhsw	82	42	at	at	IN
cord-260708-l9w5jhsw	82	43	the	the	DT
cord-260708-l9w5jhsw	82	44	base	base	NN
cord-260708-l9w5jhsw	82	45	of	of	IN
cord-260708-l9w5jhsw	82	46	the	the	DT
cord-260708-l9w5jhsw	82	47	head	head	NN
cord-260708-l9w5jhsw	82	48	domain	domain	NN
cord-260708-l9w5jhsw	82	49	of	of	IN
cord-260708-l9w5jhsw	82	50	an	an	DT
cord-260708-l9w5jhsw	82	51	adjacent	adjacent	JJ
cord-260708-l9w5jhsw	82	52	molecule	molecule	NN
cord-260708-l9w5jhsw	82	53	[	[	-LRB-
cord-260708-l9w5jhsw	82	54	174	174	CD
cord-260708-l9w5jhsw	82	55	]	]	-RRB-
cord-260708-l9w5jhsw	82	56	.	.	.
cord-260708-l9w5jhsw	83	1	In	in	IN
cord-260708-l9w5jhsw	83	2	addition	addition	NN
cord-260708-l9w5jhsw	83	3	,	,	,
cord-260708-l9w5jhsw	83	4	the	the	DT
cord-260708-l9w5jhsw	83	5	linear	linear	JJ
cord-260708-l9w5jhsw	83	6	oligomers	oligomer	NNS
cord-260708-l9w5jhsw	83	7	of	of	IN
cord-260708-l9w5jhsw	83	8	N	N	NNP
cord-260708-l9w5jhsw	83	9	were	be	VBD
cord-260708-l9w5jhsw	83	10	predicted	predict	VBN
cord-260708-l9w5jhsw	83	11	to	to	TO
cord-260708-l9w5jhsw	83	12	interact	interact	VB
cord-260708-l9w5jhsw	83	13	in	in	IN
cord-260708-l9w5jhsw	83	14	a	a	DT
cord-260708-l9w5jhsw	83	15	dimeric	dimeric	JJ
cord-260708-l9w5jhsw	83	16	manner	manner	NN
cord-260708-l9w5jhsw	83	17	to	to	TO
cord-260708-l9w5jhsw	83	18	form	form	VB
cord-260708-l9w5jhsw	83	19	an	an	DT
cord-260708-l9w5jhsw	83	20	antiparallel	antiparallel	NN
cord-260708-l9w5jhsw	83	21	double	double	JJ
cord-260708-l9w5jhsw	83	22	superhelix	superhelix	FW
cord-260708-l9w5jhsw	83	23	[	[	-LRB-
cord-260708-l9w5jhsw	83	24	31	31	CD
cord-260708-l9w5jhsw	83	25	,	,	,
cord-260708-l9w5jhsw	83	26	174	174	CD
cord-260708-l9w5jhsw	83	27	]	]	-RRB-
cord-260708-l9w5jhsw	83	28	.	.	.
cord-260708-l9w5jhsw	84	1	Further	further	JJ
cord-260708-l9w5jhsw	84	2	predictions	prediction	NNS
cord-260708-l9w5jhsw	84	3	suggest	suggest	VBP
cord-260708-l9w5jhsw	84	4	that	that	IN
cord-260708-l9w5jhsw	84	5	that	that	IN
cord-260708-l9w5jhsw	84	6	there	there	EX
cord-260708-l9w5jhsw	84	7	are	be	VBP
cord-260708-l9w5jhsw	84	8	nine	nine	CD
cord-260708-l9w5jhsw	84	9	N	n	CD
cord-260708-l9w5jhsw	84	10	molecules	molecule	NNS
cord-260708-l9w5jhsw	84	11	per	per	IN
cord-260708-l9w5jhsw	84	12	turn	turn	NN
cord-260708-l9w5jhsw	84	13	of	of	IN
cord-260708-l9w5jhsw	84	14	the	the	DT
cord-260708-l9w5jhsw	84	15	superhelix	superhelix	NN
cord-260708-l9w5jhsw	84	16	,	,	,
cord-260708-l9w5jhsw	84	17	which	which	WDT
cord-260708-l9w5jhsw	84	18	is	be	VBZ
cord-260708-l9w5jhsw	84	19	210	210	CD
cord-260708-l9w5jhsw	84	20	Å	å	NN
cord-260708-l9w5jhsw	84	21	in	in	IN
cord-260708-l9w5jhsw	84	22	diameter	diameter	NN
cord-260708-l9w5jhsw	84	23	[	[	-LRB-
cord-260708-l9w5jhsw	84	24	174	174	CD
cord-260708-l9w5jhsw	84	25	]	]	-RRB-
cord-260708-l9w5jhsw	84	26	.	.	.
cord-260708-l9w5jhsw	85	1	Additionally	additionally	RB
cord-260708-l9w5jhsw	85	2	,	,	,
cord-260708-l9w5jhsw	85	3	a	a	DT
cord-260708-l9w5jhsw	85	4	positively	positively	RB
cord-260708-l9w5jhsw	85	5	charged	charge	VBN
cord-260708-l9w5jhsw	85	6	crevice	crevice	NN
cord-260708-l9w5jhsw	85	7	located	locate	VBN
cord-260708-l9w5jhsw	85	8	on	on	IN
cord-260708-l9w5jhsw	85	9	the	the	DT
cord-260708-l9w5jhsw	85	10	outside	outside	NN
cord-260708-l9w5jhsw	85	11	of	of	IN
cord-260708-l9w5jhsw	85	12	the	the	DT
cord-260708-l9w5jhsw	85	13	double	double	JJ
cord-260708-l9w5jhsw	85	14	superhelix	superhelix	NN
cord-260708-l9w5jhsw	85	15	is	be	VBZ
cord-260708-l9w5jhsw	85	16	predicted	predict	VBN
cord-260708-l9w5jhsw	85	17	to	to	TO
cord-260708-l9w5jhsw	85	18	serve	serve	VB
cord-260708-l9w5jhsw	85	19	as	as	IN
cord-260708-l9w5jhsw	85	20	an	an	DT
cord-260708-l9w5jhsw	85	21	additional	additional	JJ
cord-260708-l9w5jhsw	85	22	RNA	rna	NN
cord-260708-l9w5jhsw	85	23	binding	bind	VBG
cord-260708-l9w5jhsw	85	24	cleft	cleft	NN
cord-260708-l9w5jhsw	85	25	[	[	-LRB-
cord-260708-l9w5jhsw	85	26	174	174	CD
cord-260708-l9w5jhsw	85	27	]	]	-RRB-
cord-260708-l9w5jhsw	85	28	.	.	.
cord-260708-l9w5jhsw	86	1	Studies	study	NNS
cord-260708-l9w5jhsw	86	2	performed	perform	VBN
cord-260708-l9w5jhsw	86	3	by	by	IN
cord-260708-l9w5jhsw	86	4	Guo	Guo	NNP
cord-260708-l9w5jhsw	86	5	and	and	CC
cord-260708-l9w5jhsw	86	6	collaborators	collaborator	NNS
cord-260708-l9w5jhsw	86	7	[	[	-LRB-
cord-260708-l9w5jhsw	86	8	77	77	CD
cord-260708-l9w5jhsw	86	9	]	]	-RRB-
cord-260708-l9w5jhsw	86	10	suggest	suggest	VBP
cord-260708-l9w5jhsw	86	11	that	that	IN
cord-260708-l9w5jhsw	86	12	the	the	DT
cord-260708-l9w5jhsw	86	13	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	86	14	N	N	NNP
cord-260708-l9w5jhsw	86	15	protein	protein	NN
cord-260708-l9w5jhsw	86	16	,	,	,
cord-260708-l9w5jhsw	86	17	when	when	WRB
cord-260708-l9w5jhsw	86	18	expressed	express	VBN
cord-260708-l9w5jhsw	86	19	without	without	IN
cord-260708-l9w5jhsw	86	20	RNA	RNA	NNP
cord-260708-l9w5jhsw	86	21	,	,	,
cord-260708-l9w5jhsw	86	22	predominantly	predominantly	RB
cord-260708-l9w5jhsw	86	23	exists	exist	VBZ
cord-260708-l9w5jhsw	86	24	as	as	IN
cord-260708-l9w5jhsw	86	25	a	a	DT
cord-260708-l9w5jhsw	86	26	monomer	monomer	NN
cord-260708-l9w5jhsw	86	27	,	,	,
cord-260708-l9w5jhsw	86	28	and	and	CC
cord-260708-l9w5jhsw	86	29	the	the	DT
cord-260708-l9w5jhsw	86	30	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	86	31	N	N	NNP
cord-260708-l9w5jhsw	86	32	protein	protein	NN
cord-260708-l9w5jhsw	86	33	is	be	VBZ
cord-260708-l9w5jhsw	86	34	only	only	RB
cord-260708-l9w5jhsw	86	35	a	a	DT
cord-260708-l9w5jhsw	86	36	weak	weak	JJ
cord-260708-l9w5jhsw	86	37	binder	binder	NN
cord-260708-l9w5jhsw	86	38	of	of	IN
cord-260708-l9w5jhsw	86	39	nonspecific	nonspecific	JJ
cord-260708-l9w5jhsw	86	40	RNA	RNA	NNP
cord-260708-l9w5jhsw	86	41	in	in	IN
cord-260708-l9w5jhsw	86	42	this	this	DT
cord-260708-l9w5jhsw	86	43	monomeric	monomeric	JJ
cord-260708-l9w5jhsw	86	44	state	state	NN
cord-260708-l9w5jhsw	86	45	[	[	-LRB-
cord-260708-l9w5jhsw	86	46	77	77	CD
cord-260708-l9w5jhsw	86	47	,	,	,
cord-260708-l9w5jhsw	86	48	80	80	CD
cord-260708-l9w5jhsw	86	49	,	,	,
cord-260708-l9w5jhsw	86	50	111	111	CD
cord-260708-l9w5jhsw	86	51	,	,	,
cord-260708-l9w5jhsw	86	52	135	135	CD
cord-260708-l9w5jhsw	86	53	]	]	-RRB-
cord-260708-l9w5jhsw	86	54	.	.	.
cord-260708-l9w5jhsw	87	1	This	this	DT
cord-260708-l9w5jhsw	87	2	suggests	suggest	VBZ
cord-260708-l9w5jhsw	87	3	that	that	IN
cord-260708-l9w5jhsw	87	4	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	87	5	N	N	NNP
cord-260708-l9w5jhsw	87	6	binds	bind	VBZ
cord-260708-l9w5jhsw	87	7	RNA	RNA	NNP
cord-260708-l9w5jhsw	87	8	only	only	RB
cord-260708-l9w5jhsw	87	9	in	in	IN
cord-260708-l9w5jhsw	87	10	the	the	DT
cord-260708-l9w5jhsw	87	11	oligomeric	oligomeric	JJ
cord-260708-l9w5jhsw	87	12	state	state	NN
cord-260708-l9w5jhsw	87	13	and/or	and/or	CC
cord-260708-l9w5jhsw	87	14	that	that	IN
cord-260708-l9w5jhsw	87	15	the	the	DT
cord-260708-l9w5jhsw	87	16	N	N	NNP
cord-260708-l9w5jhsw	87	17	recognises	recognise	VBZ
cord-260708-l9w5jhsw	87	18	specific	specific	JJ
cord-260708-l9w5jhsw	87	19	structures	structure	NNS
cord-260708-l9w5jhsw	87	20	of	of	IN
cord-260708-l9w5jhsw	87	21	viral	viral	JJ
cord-260708-l9w5jhsw	87	22	RNA	RNA	NNP
cord-260708-l9w5jhsw	87	23	,	,	,
cord-260708-l9w5jhsw	87	24	as	as	IN
cord-260708-l9w5jhsw	87	25	was	be	VBD
cord-260708-l9w5jhsw	87	26	shown	show	VBN
cord-260708-l9w5jhsw	87	27	for	for	IN
cord-260708-l9w5jhsw	87	28	viruses	virus	NNS
cord-260708-l9w5jhsw	87	29	of	of	IN
cord-260708-l9w5jhsw	87	30	the	the	DT
cord-260708-l9w5jhsw	87	31	genus	genus	NN
cord-260708-l9w5jhsw	87	32	Hantavirus	Hantavirus	NNP
cord-260708-l9w5jhsw	87	33	[	[	-LRB-
cord-260708-l9w5jhsw	87	34	110	110	CD
cord-260708-l9w5jhsw	87	35	,	,	,
cord-260708-l9w5jhsw	87	36	120	120	CD
cord-260708-l9w5jhsw	87	37	]	]	-RRB-
cord-260708-l9w5jhsw	87	38	.	.	.
cord-260708-l9w5jhsw	88	1	However	however	RB
cord-260708-l9w5jhsw	88	2	the	the	DT
cord-260708-l9w5jhsw	88	3	fact	fact	NN
cord-260708-l9w5jhsw	88	4	that	that	IN
cord-260708-l9w5jhsw	88	5	the	the	DT
cord-260708-l9w5jhsw	88	6	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	88	7	N	n	CD
cord-260708-l9w5jhsw	88	8	protein	protein	NN
cord-260708-l9w5jhsw	88	9	does	do	VBZ
cord-260708-l9w5jhsw	88	10	not	not	RB
cord-260708-l9w5jhsw	88	11	form	form	VB
cord-260708-l9w5jhsw	88	12	oligomers	oligomer	NNS
cord-260708-l9w5jhsw	88	13	without	without	IN
cord-260708-l9w5jhsw	88	14	RNA	RNA	NNP
cord-260708-l9w5jhsw	88	15	suggests	suggest	VBZ
cord-260708-l9w5jhsw	88	16	that	that	IN
cord-260708-l9w5jhsw	88	17	its	-PRON-	PRP$
cord-260708-l9w5jhsw	88	18	oligomerisation	oligomerisation	NN
cord-260708-l9w5jhsw	88	19	is	be	VBZ
cord-260708-l9w5jhsw	88	20	RNA	RNA	NNP
cord-260708-l9w5jhsw	88	21	-	-	HYPH
cord-260708-l9w5jhsw	88	22	stabilised	stabilise	VBN
cord-260708-l9w5jhsw	88	23	,	,	,
cord-260708-l9w5jhsw	88	24	where	where	WRB
cord-260708-l9w5jhsw	88	25	monomeric	monomeric	JJ
cord-260708-l9w5jhsw	88	26	N	N	NNP
cord-260708-l9w5jhsw	88	27	protein	protein	NN
cord-260708-l9w5jhsw	88	28	requires	require	VBZ
cord-260708-l9w5jhsw	88	29	binding	bind	VBG
cord-260708-l9w5jhsw	88	30	to	to	IN
cord-260708-l9w5jhsw	88	31	RNA	RNA	NNP
cord-260708-l9w5jhsw	88	32	to	to	TO
cord-260708-l9w5jhsw	88	33	form	form	VB
cord-260708-l9w5jhsw	88	34	an	an	DT
cord-260708-l9w5jhsw	88	35	oligomer	oligomer	NN
cord-260708-l9w5jhsw	88	36	,	,	,
cord-260708-l9w5jhsw	88	37	a	a	DT
cord-260708-l9w5jhsw	88	38	mechanism	mechanism	NN
cord-260708-l9w5jhsw	88	39	that	that	WDT
cord-260708-l9w5jhsw	88	40	was	be	VBD
cord-260708-l9w5jhsw	88	41	previously	previously	RB
cord-260708-l9w5jhsw	88	42	suggested	suggest	VBN
cord-260708-l9w5jhsw	88	43	for	for	IN
cord-260708-l9w5jhsw	88	44	influenza	influenza	NN
cord-260708-l9w5jhsw	88	45	A	a	DT
cord-260708-l9w5jhsw	88	46	virus	virus	NN
cord-260708-l9w5jhsw	88	47	[	[	-LRB-
cord-260708-l9w5jhsw	88	48	160	160	CD
cord-260708-l9w5jhsw	88	49	,	,	,
cord-260708-l9w5jhsw	88	50	161	161	CD
cord-260708-l9w5jhsw	88	51	]	]	-RRB-
cord-260708-l9w5jhsw	88	52	.	.	.
cord-260708-l9w5jhsw	89	1	In	in	IN
cord-260708-l9w5jhsw	89	2	a	a	DT
cord-260708-l9w5jhsw	89	3	similar	similar	JJ
cord-260708-l9w5jhsw	89	4	fashion	fashion	NN
cord-260708-l9w5jhsw	89	5	,	,	,
cord-260708-l9w5jhsw	89	6	the	the	DT
cord-260708-l9w5jhsw	89	7	N	n	CD
cord-260708-l9w5jhsw	89	8	protein	protein	NN
cord-260708-l9w5jhsw	89	9	of	of	IN
cord-260708-l9w5jhsw	89	10	Rift	Rift	NNP
cord-260708-l9w5jhsw	89	11	Valley	Valley	NNP
cord-260708-l9w5jhsw	89	12	fever	fever	NN
cord-260708-l9w5jhsw	89	13	virus	virus	NN
cord-260708-l9w5jhsw	89	14	(	(	-LRB-
cord-260708-l9w5jhsw	89	15	RVFV	rvfv	NN
cord-260708-l9w5jhsw	89	16	)	)	-RRB-
cord-260708-l9w5jhsw	89	17	can	can	MD
cord-260708-l9w5jhsw	89	18	form	form	VB
cord-260708-l9w5jhsw	89	19	only	only	RB
cord-260708-l9w5jhsw	89	20	a	a	DT
cord-260708-l9w5jhsw	89	21	short	short	JJ
cord-260708-l9w5jhsw	89	22	oligomeric	oligomeric	JJ
cord-260708-l9w5jhsw	89	23	form	form	NN
cord-260708-l9w5jhsw	89	24	in	in	IN
cord-260708-l9w5jhsw	89	25	the	the	DT
cord-260708-l9w5jhsw	89	26	absence	absence	NN
cord-260708-l9w5jhsw	89	27	of	of	IN
cord-260708-l9w5jhsw	89	28	RNA	RNA	NNP
cord-260708-l9w5jhsw	89	29	[	[	-LRB-
cord-260708-l9w5jhsw	89	30	64	64	CD
cord-260708-l9w5jhsw	89	31	]	]	-RRB-
cord-260708-l9w5jhsw	89	32	.	.	.
cord-260708-l9w5jhsw	90	1	Superimposing	superimpose	VBG
cord-260708-l9w5jhsw	90	2	the	the	DT
cord-260708-l9w5jhsw	90	3	structures	structure	NNS
cord-260708-l9w5jhsw	90	4	obtained	obtain	VBN
cord-260708-l9w5jhsw	90	5	for	for	IN
cord-260708-l9w5jhsw	90	6	the	the	DT
cord-260708-l9w5jhsw	90	7	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	90	8	N	N	NNP
cord-260708-l9w5jhsw	90	9	protein	protein	NN
cord-260708-l9w5jhsw	90	10	by	by	IN
cord-260708-l9w5jhsw	90	11	two	two	CD
cord-260708-l9w5jhsw	90	12	different	different	JJ
cord-260708-l9w5jhsw	90	13	groups	group	NNS
cord-260708-l9w5jhsw	90	14	,	,	,
cord-260708-l9w5jhsw	90	15	using	use	VBG
cord-260708-l9w5jhsw	90	16	two	two	CD
cord-260708-l9w5jhsw	90	17	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	90	18	isolates	isolate	NNS
cord-260708-l9w5jhsw	90	19	,	,	,
cord-260708-l9w5jhsw	90	20	revealed	reveal	VBD
cord-260708-l9w5jhsw	90	21	the	the	DT
cord-260708-l9w5jhsw	90	22	head	head	NN
cord-260708-l9w5jhsw	90	23	and	and	CC
cord-260708-l9w5jhsw	90	24	stalk	stalk	VB
cord-260708-l9w5jhsw	90	25	with	with	IN
cord-260708-l9w5jhsw	90	26	very	very	RB
cord-260708-l9w5jhsw	90	27	similar	similar	JJ
cord-260708-l9w5jhsw	90	28	folds	fold	NNS
cord-260708-l9w5jhsw	90	29	,	,	,
cord-260708-l9w5jhsw	90	30	but	but	CC
cord-260708-l9w5jhsw	90	31	with	with	IN
cord-260708-l9w5jhsw	90	32	a	a	DT
cord-260708-l9w5jhsw	90	33	transposition	transposition	NN
cord-260708-l9w5jhsw	90	34	of	of	IN
cord-260708-l9w5jhsw	90	35	the	the	DT
cord-260708-l9w5jhsw	90	36	stalk	stalk	NN
cord-260708-l9w5jhsw	90	37	domain	domain	NN
cord-260708-l9w5jhsw	90	38	when	when	WRB
cord-260708-l9w5jhsw	90	39	comparing	compare	VBG
cord-260708-l9w5jhsw	90	40	these	these	DT
cord-260708-l9w5jhsw	90	41	two	two	CD
cord-260708-l9w5jhsw	90	42	molecules	molecule	NNS
cord-260708-l9w5jhsw	90	43	;	;	:
cord-260708-l9w5jhsw	90	44	results	result	NNS
cord-260708-l9w5jhsw	90	45	which	which	WDT
cord-260708-l9w5jhsw	90	46	suggest	suggest	VBP
cord-260708-l9w5jhsw	90	47	a	a	DT
cord-260708-l9w5jhsw	90	48	flexibility	flexibility	NN
cord-260708-l9w5jhsw	90	49	of	of	IN
cord-260708-l9w5jhsw	90	50	the	the	DT
cord-260708-l9w5jhsw	90	51	stalk	stalk	NN
cord-260708-l9w5jhsw	90	52	domain	domain	NN
cord-260708-l9w5jhsw	90	53	and	and	CC
cord-260708-l9w5jhsw	90	54	the	the	DT
cord-260708-l9w5jhsw	90	55	possibility	possibility	NN
cord-260708-l9w5jhsw	90	56	of	of	IN
cord-260708-l9w5jhsw	90	57	different	different	JJ
cord-260708-l9w5jhsw	90	58	conformations	conformation	NNS
cord-260708-l9w5jhsw	90	59	of	of	IN
cord-260708-l9w5jhsw	90	60	N	n	CD
cord-260708-l9w5jhsw	90	61	for	for	IN
cord-260708-l9w5jhsw	90	62	different	different	JJ
cord-260708-l9w5jhsw	90	63	functions	function	NNS
cord-260708-l9w5jhsw	90	64	or	or	CC
cord-260708-l9w5jhsw	90	65	different	different	JJ
cord-260708-l9w5jhsw	90	66	states	state	NNS
cord-260708-l9w5jhsw	90	67	of	of	IN
cord-260708-l9w5jhsw	90	68	the	the	DT
cord-260708-l9w5jhsw	90	69	N	N	NNP
cord-260708-l9w5jhsw	90	70	-	-	HYPH
cord-260708-l9w5jhsw	90	71	RNA	RNA	NNP
cord-260708-l9w5jhsw	90	72	complexes	complex	NNS
cord-260708-l9w5jhsw	90	73	(	(	-LRB-
cord-260708-l9w5jhsw	90	74	e.g.	e.g.	RB
cord-260708-l9w5jhsw	90	75	,	,	,
cord-260708-l9w5jhsw	90	76	transcription	transcription	NN
cord-260708-l9w5jhsw	90	77	vs	vs	IN
cord-260708-l9w5jhsw	90	78	replication	replication	NN
cord-260708-l9w5jhsw	90	79	)	)	-RRB-
cord-260708-l9w5jhsw	90	80	[	[	-LRB-
cord-260708-l9w5jhsw	90	81	31	31	CD
cord-260708-l9w5jhsw	90	82	]	]	-RRB-
cord-260708-l9w5jhsw	90	83	.	.	.
cord-260708-l9w5jhsw	91	1	Additionally	additionally	RB
cord-260708-l9w5jhsw	91	2	,	,	,
cord-260708-l9w5jhsw	91	3	comparison	comparison	NN
cord-260708-l9w5jhsw	91	4	of	of	IN
cord-260708-l9w5jhsw	91	5	the	the	DT
cord-260708-l9w5jhsw	91	6	crystal	crystal	JJ
cord-260708-l9w5jhsw	91	7	structure	structure	NN
cord-260708-l9w5jhsw	91	8	of	of	IN
cord-260708-l9w5jhsw	91	9	the	the	DT
cord-260708-l9w5jhsw	91	10	N	N	NNP
cord-260708-l9w5jhsw	91	11	protein	protein	NN
cord-260708-l9w5jhsw	91	12	in	in	IN
cord-260708-l9w5jhsw	91	13	the	the	DT
cord-260708-l9w5jhsw	91	14	monomeric	monomeric	JJ
cord-260708-l9w5jhsw	91	15	and	and	CC
cord-260708-l9w5jhsw	91	16	oligomeric	oligomeric	JJ
cord-260708-l9w5jhsw	91	17	forms	form	NNS
cord-260708-l9w5jhsw	91	18	suggests	suggest	VBZ
cord-260708-l9w5jhsw	91	19	that	that	IN
cord-260708-l9w5jhsw	91	20	the	the	DT
cord-260708-l9w5jhsw	91	21	stalk	stalk	NN
cord-260708-l9w5jhsw	91	22	domain	domain	NN
cord-260708-l9w5jhsw	91	23	changes	change	VBZ
cord-260708-l9w5jhsw	91	24	its	-PRON-	PRP$
cord-260708-l9w5jhsw	91	25	conformation	conformation	NN
cord-260708-l9w5jhsw	91	26	upon	upon	IN
cord-260708-l9w5jhsw	91	27	oligomerisation	oligomerisation	NN
cord-260708-l9w5jhsw	91	28	,	,	,
cord-260708-l9w5jhsw	91	29	probably	probably	RB
cord-260708-l9w5jhsw	91	30	by	by	IN
cord-260708-l9w5jhsw	91	31	binding	bind	VBG
cord-260708-l9w5jhsw	91	32	to	to	IN
cord-260708-l9w5jhsw	91	33	the	the	DT
cord-260708-l9w5jhsw	91	34	oligomerisation	oligomerisation	NN
cord-260708-l9w5jhsw	91	35	groove	groove	NN
cord-260708-l9w5jhsw	91	36	on	on	IN
cord-260708-l9w5jhsw	91	37	the	the	DT
cord-260708-l9w5jhsw	91	38	head	head	NN
cord-260708-l9w5jhsw	91	39	domain	domain	NN
cord-260708-l9w5jhsw	91	40	of	of	IN
cord-260708-l9w5jhsw	91	41	the	the	DT
cord-260708-l9w5jhsw	91	42	adjacent	adjacent	JJ
cord-260708-l9w5jhsw	91	43	molecule	molecule	NN
cord-260708-l9w5jhsw	91	44	[	[	-LRB-
cord-260708-l9w5jhsw	91	45	174	174	CD
cord-260708-l9w5jhsw	91	46	]	]	-RRB-
cord-260708-l9w5jhsw	91	47	.	.	.
cord-260708-l9w5jhsw	92	1	Such	such	JJ
cord-260708-l9w5jhsw	92	2	flexibility	flexibility	NN
cord-260708-l9w5jhsw	92	3	of	of	IN
cord-260708-l9w5jhsw	92	4	the	the	DT
cord-260708-l9w5jhsw	92	5	stalk	stalk	NN
cord-260708-l9w5jhsw	92	6	domain	domain	NN
cord-260708-l9w5jhsw	92	7	has	have	VBZ
cord-260708-l9w5jhsw	92	8	also	also	RB
cord-260708-l9w5jhsw	92	9	been	be	VBN
cord-260708-l9w5jhsw	92	10	shown	show	VBN
cord-260708-l9w5jhsw	92	11	for	for	IN
cord-260708-l9w5jhsw	92	12	the	the	DT
cord-260708-l9w5jhsw	92	13	N	n	CD
cord-260708-l9w5jhsw	92	14	proteins	protein	NNS
cord-260708-l9w5jhsw	92	15	of	of	IN
cord-260708-l9w5jhsw	92	16	RVFV	RVFV	NNP
cord-260708-l9w5jhsw	92	17	and	and	CC
cord-260708-l9w5jhsw	92	18	LASV	LASV	NNP
cord-260708-l9w5jhsw	92	19	,	,	,
cord-260708-l9w5jhsw	92	20	which	which	WDT
cord-260708-l9w5jhsw	92	21	,	,	,
cord-260708-l9w5jhsw	92	22	during	during	IN
cord-260708-l9w5jhsw	92	23	binding	bind	VBG
cord-260708-l9w5jhsw	92	24	to	to	IN
cord-260708-l9w5jhsw	92	25	an	an	DT
cord-260708-l9w5jhsw	92	26	oligomerisation	oligomerisation	NN
cord-260708-l9w5jhsw	92	27	groove	groove	NN
cord-260708-l9w5jhsw	92	28	on	on	IN
cord-260708-l9w5jhsw	92	29	an	an	DT
cord-260708-l9w5jhsw	92	30	adjacent	adjacent	JJ
cord-260708-l9w5jhsw	92	31	N	n	CD
cord-260708-l9w5jhsw	92	32	molecule	molecule	NN
cord-260708-l9w5jhsw	92	33	,	,	,
cord-260708-l9w5jhsw	92	34	undergo	undergo	VB
cord-260708-l9w5jhsw	92	35	conformational	conformational	JJ
cord-260708-l9w5jhsw	92	36	changes	change	NNS
cord-260708-l9w5jhsw	92	37	exposing	expose	VBG
cord-260708-l9w5jhsw	92	38	an	an	DT
cord-260708-l9w5jhsw	92	39	RNA	rna	NN
cord-260708-l9w5jhsw	92	40	-	-	HYPH
cord-260708-l9w5jhsw	92	41	binding	bind	VBG
cord-260708-l9w5jhsw	92	42	groove	groove	NN
cord-260708-l9w5jhsw	92	43	[	[	-LRB-
cord-260708-l9w5jhsw	92	44	64	64	CD
cord-260708-l9w5jhsw	92	45	,	,	,
cord-260708-l9w5jhsw	92	46	80	80	CD
cord-260708-l9w5jhsw	92	47	]	]	-RRB-
cord-260708-l9w5jhsw	92	48	.	.	.
cord-260708-l9w5jhsw	93	1	These	these	DT
cord-260708-l9w5jhsw	93	2	structural	structural	JJ
cord-260708-l9w5jhsw	93	3	data	datum	NNS
cord-260708-l9w5jhsw	93	4	have	have	VBP
cord-260708-l9w5jhsw	93	5	led	lead	VBN
cord-260708-l9w5jhsw	93	6	to	to	IN
cord-260708-l9w5jhsw	93	7	suggestions	suggestion	NNS
cord-260708-l9w5jhsw	93	8	of	of	IN
cord-260708-l9w5jhsw	93	9	possible	possible	JJ
cord-260708-l9w5jhsw	93	10	models	model	NNS
cord-260708-l9w5jhsw	93	11	for	for	IN
cord-260708-l9w5jhsw	93	12	the	the	DT
cord-260708-l9w5jhsw	93	13	initiation	initiation	NN
cord-260708-l9w5jhsw	93	14	of	of	IN
cord-260708-l9w5jhsw	93	15	transcription	transcription	NN
cord-260708-l9w5jhsw	93	16	and	and	CC
cord-260708-l9w5jhsw	93	17	replication	replication	NN
cord-260708-l9w5jhsw	93	18	.	.	.
cord-260708-l9w5jhsw	94	1	Transcription	transcription	NN
cord-260708-l9w5jhsw	94	2	of	of	IN
cord-260708-l9w5jhsw	94	3	viral	viral	JJ
cord-260708-l9w5jhsw	94	4	mRNAs	mRNAs	NNPS
cord-260708-l9w5jhsw	94	5	by	by	IN
cord-260708-l9w5jhsw	94	6	nairoviruses	nairoviruses	NNP
cord-260708-l9w5jhsw	94	7	utilises	utilise	VBZ
cord-260708-l9w5jhsw	94	8	short	short	JJ
cord-260708-l9w5jhsw	94	9	capped	cap	VBN
cord-260708-l9w5jhsw	94	10	RNA	rna	NN
cord-260708-l9w5jhsw	94	11	fragments	fragment	NNS
cord-260708-l9w5jhsw	94	12	(	(	-LRB-
cord-260708-l9w5jhsw	94	13	10	10	CD
cord-260708-l9w5jhsw	94	14	-	-	SYM
cord-260708-l9w5jhsw	94	15	20	20	CD
cord-260708-l9w5jhsw	94	16	nt	nt	RB
cord-260708-l9w5jhsw	94	17	in	in	IN
cord-260708-l9w5jhsw	94	18	length	length	NN
cord-260708-l9w5jhsw	94	19	)	)	-RRB-
cord-260708-l9w5jhsw	94	20	derived	derive	VBN
cord-260708-l9w5jhsw	94	21	from	from	IN
cord-260708-l9w5jhsw	94	22	host	host	NN
cord-260708-l9w5jhsw	94	23	mRNAs	mrna	NNS
cord-260708-l9w5jhsw	94	24	as	as	IN
cord-260708-l9w5jhsw	94	25	primers	primer	NNS
cord-260708-l9w5jhsw	94	26	[	[	-LRB-
cord-260708-l9w5jhsw	94	27	90	90	CD
cord-260708-l9w5jhsw	94	28	]	]	-RRB-
cord-260708-l9w5jhsw	94	29	.	.	.
cord-260708-l9w5jhsw	95	1	Incubation	incubation	NN
cord-260708-l9w5jhsw	95	2	of	of	IN
cord-260708-l9w5jhsw	95	3	the	the	DT
cord-260708-l9w5jhsw	95	4	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	95	5	N	N	NNP
cord-260708-l9w5jhsw	95	6	protein	protein	NN
cord-260708-l9w5jhsw	95	7	with	with	IN
cord-260708-l9w5jhsw	95	8	primer	primer	NN
cord-260708-l9w5jhsw	95	9	-	-	HYPH
cord-260708-l9w5jhsw	95	10	length	length	NN
cord-260708-l9w5jhsw	95	11	ssRNA	ssrna	NN
cord-260708-l9w5jhsw	95	12	resulted	result	VBN
cord-260708-l9w5jhsw	95	13	in	in	IN
cord-260708-l9w5jhsw	95	14	a	a	DT
cord-260708-l9w5jhsw	95	15	conformational	conformational	JJ
cord-260708-l9w5jhsw	95	16	change	change	NN
cord-260708-l9w5jhsw	95	17	of	of	IN
cord-260708-l9w5jhsw	95	18	the	the	DT
cord-260708-l9w5jhsw	95	19	stalk	stalk	NN
cord-260708-l9w5jhsw	95	20	domain	domain	NN
cord-260708-l9w5jhsw	95	21	,	,	,
cord-260708-l9w5jhsw	95	22	which	which	WDT
cord-260708-l9w5jhsw	95	23	resulted	result	VBD
cord-260708-l9w5jhsw	95	24	in	in	IN
cord-260708-l9w5jhsw	95	25	disruption	disruption	NN
cord-260708-l9w5jhsw	95	26	of	of	IN
cord-260708-l9w5jhsw	95	27	the	the	DT
cord-260708-l9w5jhsw	95	28	oligomeric	oligomeric	JJ
cord-260708-l9w5jhsw	95	29	interactions	interaction	NNS
cord-260708-l9w5jhsw	95	30	and	and	CC
cord-260708-l9w5jhsw	95	31	release	release	NN
cord-260708-l9w5jhsw	95	32	of	of	IN
cord-260708-l9w5jhsw	95	33	the	the	DT
cord-260708-l9w5jhsw	95	34	monomeric	monomeric	JJ
cord-260708-l9w5jhsw	95	35	N	N	NNP
cord-260708-l9w5jhsw	95	36	protein	protein	NN
cord-260708-l9w5jhsw	95	37	from	from	IN
cord-260708-l9w5jhsw	95	38	the	the	DT
cord-260708-l9w5jhsw	95	39	antiparallel	antiparallel	JJ
cord-260708-l9w5jhsw	95	40	double	double	JJ
cord-260708-l9w5jhsw	95	41	superhelix	superhelix	FW
cord-260708-l9w5jhsw	95	42	[	[	-LRB-
cord-260708-l9w5jhsw	95	43	174	174	CD
cord-260708-l9w5jhsw	95	44	]	]	-RRB-
cord-260708-l9w5jhsw	95	45	.	.	.
cord-260708-l9w5jhsw	96	1	As	as	IN
cord-260708-l9w5jhsw	96	2	discussed	discuss	VBN
cord-260708-l9w5jhsw	96	3	by	by	IN
cord-260708-l9w5jhsw	96	4	Wang	Wang	NNP
cord-260708-l9w5jhsw	96	5	et	et	NNP
cord-260708-l9w5jhsw	96	6	al	al	NNP
cord-260708-l9w5jhsw	96	7	.	.	.
cord-260708-l9w5jhsw	97	1	,	,	,
cord-260708-l9w5jhsw	97	2	presentation	presentation	NN
cord-260708-l9w5jhsw	97	3	of	of	IN
cord-260708-l9w5jhsw	97	4	the	the	DT
cord-260708-l9w5jhsw	97	5	capped	cap	VBN
cord-260708-l9w5jhsw	97	6	primers	primer	NNS
cord-260708-l9w5jhsw	97	7	to	to	IN
cord-260708-l9w5jhsw	97	8	the	the	DT
cord-260708-l9w5jhsw	97	9	ribonucleoprotein	ribonucleoprotein	NN
cord-260708-l9w5jhsw	97	10	(	(	-LRB-
cord-260708-l9w5jhsw	97	11	RNP	RNP	NNP
cord-260708-l9w5jhsw	97	12	)	)	-RRB-
cord-260708-l9w5jhsw	97	13	may	may	MD
cord-260708-l9w5jhsw	97	14	initiate	initiate	VB
cord-260708-l9w5jhsw	97	15	conformational	conformational	JJ
cord-260708-l9w5jhsw	97	16	changes	change	NNS
cord-260708-l9w5jhsw	97	17	in	in	IN
cord-260708-l9w5jhsw	97	18	the	the	DT
cord-260708-l9w5jhsw	97	19	stalk	stalk	NN
cord-260708-l9w5jhsw	97	20	domain	domain	NN
cord-260708-l9w5jhsw	97	21	,	,	,
cord-260708-l9w5jhsw	97	22	leading	lead	VBG
cord-260708-l9w5jhsw	97	23	to	to	IN
cord-260708-l9w5jhsw	97	24	the	the	DT
cord-260708-l9w5jhsw	97	25	release	release	NN
cord-260708-l9w5jhsw	97	26	of	of	IN
cord-260708-l9w5jhsw	97	27	monomeric	monomeric	JJ
cord-260708-l9w5jhsw	97	28	N	n	CD
cord-260708-l9w5jhsw	97	29	and	and	CC
cord-260708-l9w5jhsw	97	30	exposing	expose	VBG
cord-260708-l9w5jhsw	97	31	vRNA	vRNA	NNS
cord-260708-l9w5jhsw	97	32	to	to	IN
cord-260708-l9w5jhsw	97	33	the	the	DT
cord-260708-l9w5jhsw	97	34	primer	primer	NN
cord-260708-l9w5jhsw	97	35	and	and	CC
cord-260708-l9w5jhsw	97	36	the	the	DT
cord-260708-l9w5jhsw	97	37	viral	viral	JJ
cord-260708-l9w5jhsw	97	38	polymerase	polymerase	NN
cord-260708-l9w5jhsw	97	39	.	.	.
cord-260708-l9w5jhsw	98	1	Given	give	VBN
cord-260708-l9w5jhsw	98	2	that	that	DT
cord-260708-l9w5jhsw	98	3	head	head	NN
cord-260708-l9w5jhsw	98	4	-	-	HYPH
cord-260708-l9w5jhsw	98	5	to	to	IN
cord-260708-l9w5jhsw	98	6	-	-	HYPH
cord-260708-l9w5jhsw	98	7	stalk	stalk	VB
cord-260708-l9w5jhsw	98	8	interactions	interaction	NNS
cord-260708-l9w5jhsw	98	9	between	between	IN
cord-260708-l9w5jhsw	98	10	two	two	CD
cord-260708-l9w5jhsw	98	11	adjacent	adjacent	JJ
cord-260708-l9w5jhsw	98	12	N	n	CD
cord-260708-l9w5jhsw	98	13	molecules	molecule	NNS
cord-260708-l9w5jhsw	98	14	have	have	VBP
cord-260708-l9w5jhsw	98	15	also	also	RB
cord-260708-l9w5jhsw	98	16	been	be	VBN
cord-260708-l9w5jhsw	98	17	observed	observe	VBN
cord-260708-l9w5jhsw	98	18	for	for	IN
cord-260708-l9w5jhsw	98	19	RVFV	RVFV	NNP
cord-260708-l9w5jhsw	98	20	,	,	,
cord-260708-l9w5jhsw	98	21	LASV	LASV	NNP
cord-260708-l9w5jhsw	98	22	,	,	,
cord-260708-l9w5jhsw	98	23	and	and	CC
cord-260708-l9w5jhsw	98	24	Bunyamwera	Bunyamwera	NNP
cord-260708-l9w5jhsw	98	25	virus	virus	NN
cord-260708-l9w5jhsw	98	26	(	(	-LRB-
cord-260708-l9w5jhsw	98	27	BUNV	BUNV	NNP
cord-260708-l9w5jhsw	98	28	)	)	-RRB-
cord-260708-l9w5jhsw	98	29	[	[	-LRB-
cord-260708-l9w5jhsw	98	30	9	9	CD
cord-260708-l9w5jhsw	98	31	,	,	,
cord-260708-l9w5jhsw	98	32	64	64	CD
cord-260708-l9w5jhsw	98	33	,	,	,
cord-260708-l9w5jhsw	98	34	80	80	CD
cord-260708-l9w5jhsw	98	35	]	]	-RRB-
cord-260708-l9w5jhsw	98	36	,	,	,
cord-260708-l9w5jhsw	98	37	it	-PRON-	PRP
cord-260708-l9w5jhsw	98	38	seems	seem	VBZ
cord-260708-l9w5jhsw	98	39	likely	likely	JJ
cord-260708-l9w5jhsw	98	40	that	that	IN
cord-260708-l9w5jhsw	98	41	the	the	DT
cord-260708-l9w5jhsw	98	42	model	model	NN
cord-260708-l9w5jhsw	98	43	proposed	propose	VBD
cord-260708-l9w5jhsw	98	44	for	for	IN
cord-260708-l9w5jhsw	98	45	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	98	46	may	may	MD
cord-260708-l9w5jhsw	98	47	be	be	VB
cord-260708-l9w5jhsw	98	48	biologically	biologically	RB
cord-260708-l9w5jhsw	98	49	valid	valid	JJ
cord-260708-l9w5jhsw	98	50	.	.	.
cord-260708-l9w5jhsw	99	1	The	the	DT
cord-260708-l9w5jhsw	99	2	N	n	CD
cord-260708-l9w5jhsw	99	3	protein	protein	NN
cord-260708-l9w5jhsw	99	4	of	of	IN
cord-260708-l9w5jhsw	99	5	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	99	6	has	have	VBZ
cord-260708-l9w5jhsw	99	7	also	also	RB
cord-260708-l9w5jhsw	99	8	been	be	VBN
cord-260708-l9w5jhsw	99	9	shown	show	VBN
cord-260708-l9w5jhsw	99	10	to	to	TO
cord-260708-l9w5jhsw	99	11	have	have	VB
cord-260708-l9w5jhsw	99	12	nuclease	nuclease	NN
cord-260708-l9w5jhsw	99	13	activity	activity	NN
cord-260708-l9w5jhsw	99	14	specific	specific	JJ
cord-260708-l9w5jhsw	99	15	for	for	IN
cord-260708-l9w5jhsw	99	16	dsDNA	dsdna	RB
cord-260708-l9w5jhsw	99	17	and	and	CC
cord-260708-l9w5jhsw	99	18	ssDNA	ssdna	JJ
cord-260708-l9w5jhsw	99	19	(	(	-LRB-
cord-260708-l9w5jhsw	99	20	but	but	CC
cord-260708-l9w5jhsw	99	21	not	not	RB
cord-260708-l9w5jhsw	99	22	for	for	IN
cord-260708-l9w5jhsw	99	23	RNA	RNA	NNP
cord-260708-l9w5jhsw	99	24	)	)	-RRB-
cord-260708-l9w5jhsw	99	25	;	;	:
cord-260708-l9w5jhsw	99	26	the	the	DT
cord-260708-l9w5jhsw	99	27	importance	importance	NN
cord-260708-l9w5jhsw	99	28	of	of	IN
cord-260708-l9w5jhsw	99	29	this	this	DT
cord-260708-l9w5jhsw	99	30	DNase	DNase	NNP
cord-260708-l9w5jhsw	99	31	activity	activity	NN
cord-260708-l9w5jhsw	99	32	and	and	CC
cord-260708-l9w5jhsw	99	33	its	-PRON-	PRP$
cord-260708-l9w5jhsw	99	34	function	function	NN
cord-260708-l9w5jhsw	99	35	in	in	IN
cord-260708-l9w5jhsw	99	36	the	the	DT
cord-260708-l9w5jhsw	99	37	virus	virus	NN
cord-260708-l9w5jhsw	99	38	life	life	NN
cord-260708-l9w5jhsw	99	39	cycle	cycle	NN
cord-260708-l9w5jhsw	99	40	are	be	VBP
cord-260708-l9w5jhsw	99	41	unknown	unknown	JJ
cord-260708-l9w5jhsw	99	42	[	[	-LRB-
cord-260708-l9w5jhsw	99	43	77	77	CD
cord-260708-l9w5jhsw	99	44	]	]	-RRB-
cord-260708-l9w5jhsw	99	45	.	.	.
cord-260708-l9w5jhsw	100	1	The	the	DT
cord-260708-l9w5jhsw	100	2	residues	residue	NNS
cord-260708-l9w5jhsw	100	3	involved	involve	VBN
cord-260708-l9w5jhsw	100	4	in	in	IN
cord-260708-l9w5jhsw	100	5	the	the	DT
cord-260708-l9w5jhsw	100	6	nuclease	nuclease	NN
cord-260708-l9w5jhsw	100	7	activity	activity	NN
cord-260708-l9w5jhsw	100	8	are	be	VBP
cord-260708-l9w5jhsw	100	9	located	locate	VBN
cord-260708-l9w5jhsw	100	10	in	in	IN
cord-260708-l9w5jhsw	100	11	the	the	DT
cord-260708-l9w5jhsw	100	12	globular	globular	JJ
cord-260708-l9w5jhsw	100	13	head	head	NN
cord-260708-l9w5jhsw	100	14	domain	domain	NN
cord-260708-l9w5jhsw	100	15	of	of	IN
cord-260708-l9w5jhsw	100	16	the	the	DT
cord-260708-l9w5jhsw	100	17	N	N	NNP
cord-260708-l9w5jhsw	100	18	protein	protein	NN
cord-260708-l9w5jhsw	100	19	and	and	CC
cord-260708-l9w5jhsw	100	20	are	be	VBP
cord-260708-l9w5jhsw	100	21	conserved	conserve	VBN
cord-260708-l9w5jhsw	100	22	in	in	IN
cord-260708-l9w5jhsw	100	23	all	all	DT
cord-260708-l9w5jhsw	100	24	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	100	25	[	[	-LRB-
cord-260708-l9w5jhsw	100	26	77	77	CD
cord-260708-l9w5jhsw	100	27	]	]	-RRB-
cord-260708-l9w5jhsw	100	28	.	.	.
cord-260708-l9w5jhsw	101	1	In	in	IN
cord-260708-l9w5jhsw	101	2	contrast	contrast	NN
cord-260708-l9w5jhsw	101	3	,	,	,
cord-260708-l9w5jhsw	101	4	the	the	DT
cord-260708-l9w5jhsw	101	5	N	n	CD
cord-260708-l9w5jhsw	101	6	protein	protein	NN
cord-260708-l9w5jhsw	101	7	of	of	IN
cord-260708-l9w5jhsw	101	8	LASV	LASV	NNP
cord-260708-l9w5jhsw	101	9	,	,	,
cord-260708-l9w5jhsw	101	10	the	the	DT
cord-260708-l9w5jhsw	101	11	head	head	NN
cord-260708-l9w5jhsw	101	12	domain	domain	NN
cord-260708-l9w5jhsw	101	13	of	of	IN
cord-260708-l9w5jhsw	101	14	which	which	WDT
cord-260708-l9w5jhsw	101	15	exhibits	exhibit	VBZ
cord-260708-l9w5jhsw	101	16	high	high	JJ
cord-260708-l9w5jhsw	101	17	structural	structural	JJ
cord-260708-l9w5jhsw	101	18	homology	homology	NN
cord-260708-l9w5jhsw	101	19	with	with	IN
cord-260708-l9w5jhsw	101	20	that	that	DT
cord-260708-l9w5jhsw	101	21	of	of	IN
cord-260708-l9w5jhsw	101	22	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	101	23	,	,	,
cord-260708-l9w5jhsw	101	24	has	have	VBZ
cord-260708-l9w5jhsw	101	25	RNA	rna	NN
cord-260708-l9w5jhsw	101	26	-	-	HYPH
cord-260708-l9w5jhsw	101	27	specific	specific	JJ
cord-260708-l9w5jhsw	101	28	nuclease	nuclease	NN
cord-260708-l9w5jhsw	101	29	activity	activity	NN
cord-260708-l9w5jhsw	101	30	[	[	-LRB-
cord-260708-l9w5jhsw	101	31	79	79	CD
cord-260708-l9w5jhsw	101	32	,	,	,
cord-260708-l9w5jhsw	101	33	80	80	CD
cord-260708-l9w5jhsw	101	34	,	,	,
cord-260708-l9w5jhsw	101	35	130	130	CD
cord-260708-l9w5jhsw	101	36	]	]	-RRB-
cord-260708-l9w5jhsw	101	37	.	.	.
cord-260708-l9w5jhsw	102	1	The	the	DT
cord-260708-l9w5jhsw	102	2	N	N	NNP
cord-260708-l9w5jhsw	102	3	protein	protein	NN
cord-260708-l9w5jhsw	102	4	of	of	IN
cord-260708-l9w5jhsw	102	5	nairoviruses	nairoviruses	NNPS
cord-260708-l9w5jhsw	102	6	also	also	RB
cord-260708-l9w5jhsw	102	7	contains	contain	VBZ
cord-260708-l9w5jhsw	102	8	a	a	DT
cord-260708-l9w5jhsw	102	9	conserved	conserved	JJ
cord-260708-l9w5jhsw	102	10	sequence	sequence	NN
cord-260708-l9w5jhsw	102	11	signature	signature	NN
cord-260708-l9w5jhsw	102	12	specific	specific	JJ
cord-260708-l9w5jhsw	102	13	for	for	IN
cord-260708-l9w5jhsw	102	14	catalytic	catalytic	JJ
cord-260708-l9w5jhsw	102	15	motif	motif	NN
cord-260708-l9w5jhsw	102	16	II	II	NNP
cord-260708-l9w5jhsw	102	17	(	(	-LRB-
cord-260708-l9w5jhsw	102	18	CMII	CMII	NNP
cord-260708-l9w5jhsw	102	19	)	)	-RRB-
cord-260708-l9w5jhsw	102	20	of	of	IN
cord-260708-l9w5jhsw	102	21	N-6	n-6	JJ
cord-260708-l9w5jhsw	102	22	adenine	adenine	NN
cord-260708-l9w5jhsw	102	23	-	-	HYPH
cord-260708-l9w5jhsw	102	24	specific	specific	JJ
cord-260708-l9w5jhsw	102	25	DNA	dna	NN
cord-260708-l9w5jhsw	102	26	methylases	methylase	NNS
cord-260708-l9w5jhsw	102	27	(	(	-LRB-
cord-260708-l9w5jhsw	102	28	Lasecka	Lasecka	NNPS
cord-260708-l9w5jhsw	102	29	and	and	CC
cord-260708-l9w5jhsw	102	30	Baron	Baron	NNP
cord-260708-l9w5jhsw	102	31	,	,	,
cord-260708-l9w5jhsw	102	32	unpublished	unpublished	JJ
cord-260708-l9w5jhsw	102	33	)	)	-RRB-
cord-260708-l9w5jhsw	103	1	(	(	-LRB-
cord-260708-l9w5jhsw	103	2	Fig	Fig	NNP
cord-260708-l9w5jhsw	103	3	.	.	NNP
cord-260708-l9w5jhsw	103	4	2	2	CD
cord-260708-l9w5jhsw	103	5	)	)	-RRB-
cord-260708-l9w5jhsw	103	6	,	,	,
cord-260708-l9w5jhsw	103	7	where	where	WRB
cord-260708-l9w5jhsw	103	8	the	the	DT
cord-260708-l9w5jhsw	103	9	conserved	conserve	VBN
cord-260708-l9w5jhsw	103	10	motif	motif	NN
cord-260708-l9w5jhsw	103	11	NPPW	NPPW	NNP
cord-260708-l9w5jhsw	103	12	could	could	MD
cord-260708-l9w5jhsw	103	13	be	be	VB
cord-260708-l9w5jhsw	103	14	involved	involve	VBN
cord-260708-l9w5jhsw	103	15	in	in	IN
cord-260708-l9w5jhsw	103	16	substrate	substrate	NN
cord-260708-l9w5jhsw	103	17	binding	binding	NN
cord-260708-l9w5jhsw	103	18	or	or	CC
cord-260708-l9w5jhsw	103	19	in	in	IN
cord-260708-l9w5jhsw	103	20	catalytic	catalytic	JJ
cord-260708-l9w5jhsw	103	21	activity	activity	NN
cord-260708-l9w5jhsw	103	22	[	[	-LRB-
cord-260708-l9w5jhsw	103	23	97	97	CD
cord-260708-l9w5jhsw	103	24	,	,	,
cord-260708-l9w5jhsw	103	25	164	164	CD
cord-260708-l9w5jhsw	103	26	]	]	-RRB-
cord-260708-l9w5jhsw	103	27	.	.	.
cord-260708-l9w5jhsw	104	1	The	the	DT
cord-260708-l9w5jhsw	104	2	motif	motif	NN
cord-260708-l9w5jhsw	104	3	is	be	VBZ
cord-260708-l9w5jhsw	104	4	located	locate	VBN
cord-260708-l9w5jhsw	104	5	on	on	IN
cord-260708-l9w5jhsw	104	6	an	an	DT
cord-260708-l9w5jhsw	104	7	exposed	expose	VBN
cord-260708-l9w5jhsw	104	8	loop	loop	NN
cord-260708-l9w5jhsw	104	9	of	of	IN
cord-260708-l9w5jhsw	104	10	the	the	DT
cord-260708-l9w5jhsw	104	11	stalk	stalk	NN
cord-260708-l9w5jhsw	104	12	domain	domain	NN
cord-260708-l9w5jhsw	104	13	,	,	,
cord-260708-l9w5jhsw	104	14	and	and	CC
cord-260708-l9w5jhsw	104	15	the	the	DT
cord-260708-l9w5jhsw	104	16	function	function	NN
cord-260708-l9w5jhsw	104	17	and	and	CC
cord-260708-l9w5jhsw	104	18	potential	potential	JJ
cord-260708-l9w5jhsw	104	19	importance	importance	NN
cord-260708-l9w5jhsw	104	20	of	of	IN
cord-260708-l9w5jhsw	104	21	this	this	DT
cord-260708-l9w5jhsw	104	22	motif	motif	NN
cord-260708-l9w5jhsw	104	23	still	still	RB
cord-260708-l9w5jhsw	104	24	need	need	VBP
cord-260708-l9w5jhsw	104	25	to	to	TO
cord-260708-l9w5jhsw	104	26	be	be	VB
cord-260708-l9w5jhsw	104	27	determined	determine	VBN
cord-260708-l9w5jhsw	104	28	.	.	.
cord-260708-l9w5jhsw	105	1	The	the	DT
cord-260708-l9w5jhsw	105	2	methylation	methylation	NN
cord-260708-l9w5jhsw	105	3	of	of	IN
cord-260708-l9w5jhsw	105	4	DNA	DNA	NNP
cord-260708-l9w5jhsw	105	5	is	be	VBZ
cord-260708-l9w5jhsw	105	6	used	use	VBN
cord-260708-l9w5jhsw	105	7	for	for	IN
cord-260708-l9w5jhsw	105	8	regulation	regulation	NN
cord-260708-l9w5jhsw	105	9	of	of	IN
cord-260708-l9w5jhsw	105	10	gene	gene	NN
cord-260708-l9w5jhsw	105	11	expression	expression	NN
cord-260708-l9w5jhsw	105	12	,	,	,
cord-260708-l9w5jhsw	105	13	but	but	CC
cord-260708-l9w5jhsw	105	14	so	so	RB
cord-260708-l9w5jhsw	105	15	far	far	RB
cord-260708-l9w5jhsw	105	16	there	there	EX
cord-260708-l9w5jhsw	105	17	is	be	VBZ
cord-260708-l9w5jhsw	105	18	no	no	DT
cord-260708-l9w5jhsw	105	19	indication	indication	NN
cord-260708-l9w5jhsw	105	20	that	that	IN
cord-260708-l9w5jhsw	105	21	the	the	DT
cord-260708-l9w5jhsw	105	22	N	N	NNP
cord-260708-l9w5jhsw	105	23	protein	protein	NN
cord-260708-l9w5jhsw	105	24	of	of	IN
cord-260708-l9w5jhsw	105	25	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	105	26	travels	travel	VBZ
cord-260708-l9w5jhsw	105	27	to	to	IN
cord-260708-l9w5jhsw	105	28	the	the	DT
cord-260708-l9w5jhsw	105	29	nucleus	nucleus	NN
cord-260708-l9w5jhsw	105	30	;	;	:
cord-260708-l9w5jhsw	105	31	the	the	DT
cord-260708-l9w5jhsw	105	32	protein	protein	NN
cord-260708-l9w5jhsw	105	33	does	do	VBZ
cord-260708-l9w5jhsw	105	34	not	not	RB
cord-260708-l9w5jhsw	105	35	contain	contain	VB
cord-260708-l9w5jhsw	105	36	a	a	DT
cord-260708-l9w5jhsw	105	37	classical	classical	JJ
cord-260708-l9w5jhsw	105	38	nuclear	nuclear	JJ
cord-260708-l9w5jhsw	105	39	localisation	localisation	NN
cord-260708-l9w5jhsw	105	40	signal	signal	NN
cord-260708-l9w5jhsw	105	41	(	(	-LRB-
cord-260708-l9w5jhsw	105	42	NLS	NLS	NNP
cord-260708-l9w5jhsw	105	43	)	)	-RRB-
cord-260708-l9w5jhsw	105	44	,	,	,
cord-260708-l9w5jhsw	105	45	nor	nor	CC
cord-260708-l9w5jhsw	105	46	does	do	VBZ
cord-260708-l9w5jhsw	105	47	it	-PRON-	PRP
cord-260708-l9w5jhsw	105	48	accumulate	accumulate	VB
cord-260708-l9w5jhsw	105	49	in	in	IN
cord-260708-l9w5jhsw	105	50	the	the	DT
cord-260708-l9w5jhsw	105	51	nucleus	nucleus	NN
cord-260708-l9w5jhsw	105	52	of	of	IN
cord-260708-l9w5jhsw	105	53	infected	infected	JJ
cord-260708-l9w5jhsw	105	54	or	or	CC
cord-260708-l9w5jhsw	105	55	transfected	transfecte	VBN
cord-260708-l9w5jhsw	105	56	cells	cell	NNS
cord-260708-l9w5jhsw	105	57	.	.	.
cord-260708-l9w5jhsw	106	1	N6	N6	NNP
cord-260708-l9w5jhsw	106	2	methylation	methylation	NN
cord-260708-l9w5jhsw	106	3	is	be	VBZ
cord-260708-l9w5jhsw	106	4	also	also	RB
cord-260708-l9w5jhsw	106	5	used	use	VBN
cord-260708-l9w5jhsw	106	6	as	as	IN
cord-260708-l9w5jhsw	106	7	a	a	DT
cord-260708-l9w5jhsw	106	8	posttranscriptional	posttranscriptional	JJ
cord-260708-l9w5jhsw	106	9	modification	modification	NN
cord-260708-l9w5jhsw	106	10	of	of	IN
cord-260708-l9w5jhsw	106	11	mRNA	mrna	NN
cord-260708-l9w5jhsw	106	12	,	,	,
cord-260708-l9w5jhsw	106	13	and	and	CC
cord-260708-l9w5jhsw	106	14	RNA	RNA	NNP
cord-260708-l9w5jhsw	106	15	methyltransferases	methyltransferase	NNS
cord-260708-l9w5jhsw	106	16	appear	appear	VBP
cord-260708-l9w5jhsw	106	17	to	to	TO
cord-260708-l9w5jhsw	106	18	contain	contain	VB
cord-260708-l9w5jhsw	106	19	motifs	motif	NNS
cord-260708-l9w5jhsw	106	20	very	very	RB
cord-260708-l9w5jhsw	106	21	similar	similar	JJ
cord-260708-l9w5jhsw	106	22	to	to	IN
cord-260708-l9w5jhsw	106	23	the	the	DT
cord-260708-l9w5jhsw	106	24	CMI	CMI	NNP
cord-260708-l9w5jhsw	106	25	and	and	CC
cord-260708-l9w5jhsw	106	26	CMII	CMII	NNP
cord-260708-l9w5jhsw	106	27	motifs	motif	NNS
cord-260708-l9w5jhsw	106	28	identified	identify	VBN
cord-260708-l9w5jhsw	106	29	in	in	IN
cord-260708-l9w5jhsw	106	30	DNA	DNA	NNP
cord-260708-l9w5jhsw	106	31	methyltransferases	methyltransferase	NNS
cord-260708-l9w5jhsw	106	32	(	(	-LRB-
cord-260708-l9w5jhsw	106	33	reviewed	review	VBN
cord-260708-l9w5jhsw	106	34	in	in	IN
cord-260708-l9w5jhsw	106	35	ref	ref	NN
cord-260708-l9w5jhsw	106	36	.	.	.
cord-260708-l9w5jhsw	107	1	[	[	-LRB-
cord-260708-l9w5jhsw	107	2	119	119	CD
cord-260708-l9w5jhsw	107	3	]	]	-RRB-
cord-260708-l9w5jhsw	107	4	)	)	-RRB-
cord-260708-l9w5jhsw	107	5	;	;	:
cord-260708-l9w5jhsw	107	6	further	further	JJ
cord-260708-l9w5jhsw	107	7	studies	study	NNS
cord-260708-l9w5jhsw	107	8	are	be	VBP
cord-260708-l9w5jhsw	107	9	required	require	VBN
cord-260708-l9w5jhsw	107	10	to	to	TO
cord-260708-l9w5jhsw	107	11	determine	determine	VB
cord-260708-l9w5jhsw	107	12	if	if	IN
cord-260708-l9w5jhsw	107	13	the	the	DT
cord-260708-l9w5jhsw	107	14	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	107	15	N	n	CD
cord-260708-l9w5jhsw	107	16	protein	protein	NN
cord-260708-l9w5jhsw	107	17	can	can	MD
cord-260708-l9w5jhsw	107	18	modify	modify	VB
cord-260708-l9w5jhsw	107	19	its	-PRON-	PRP$
cord-260708-l9w5jhsw	107	20	own	own	JJ
cord-260708-l9w5jhsw	107	21	or	or	CC
cord-260708-l9w5jhsw	107	22	host	host	NN
cord-260708-l9w5jhsw	107	23	cell	cell	NN
cord-260708-l9w5jhsw	107	24	RNAs	rna	NNS
cord-260708-l9w5jhsw	107	25	in	in	IN
cord-260708-l9w5jhsw	107	26	this	this	DT
cord-260708-l9w5jhsw	107	27	way	way	NN
cord-260708-l9w5jhsw	107	28	.	.	.
cord-260708-l9w5jhsw	108	1	Like	like	IN
cord-260708-l9w5jhsw	108	2	those	those	DT
cord-260708-l9w5jhsw	108	3	of	of	IN
cord-260708-l9w5jhsw	108	4	members	member	NNS
cord-260708-l9w5jhsw	108	5	of	of	IN
cord-260708-l9w5jhsw	108	6	the	the	DT
cord-260708-l9w5jhsw	108	7	other	other	JJ
cord-260708-l9w5jhsw	108	8	genera	genus	NNS
cord-260708-l9w5jhsw	108	9	of	of	IN
cord-260708-l9w5jhsw	108	10	the	the	DT
cord-260708-l9w5jhsw	108	11	family	family	NN
cord-260708-l9w5jhsw	108	12	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	108	13	,	,	,
cord-260708-l9w5jhsw	108	14	the	the	DT
cord-260708-l9w5jhsw	108	15	M	M	NNP
cord-260708-l9w5jhsw	108	16	segment	segment	NN
cord-260708-l9w5jhsw	108	17	of	of	IN
cord-260708-l9w5jhsw	108	18	nairoviruses	nairoviruses	NNP
cord-260708-l9w5jhsw	108	19	contains	contain	VBZ
cord-260708-l9w5jhsw	108	20	a	a	DT
cord-260708-l9w5jhsw	108	21	single	single	JJ
cord-260708-l9w5jhsw	108	22	open	open	JJ
cord-260708-l9w5jhsw	108	23	reading	reading	NN
cord-260708-l9w5jhsw	108	24	frame	frame	NN
cord-260708-l9w5jhsw	108	25	(	(	-LRB-
cord-260708-l9w5jhsw	108	26	ORF	ORF	NNP
cord-260708-l9w5jhsw	108	27	)	)	-RRB-
cord-260708-l9w5jhsw	108	28	encoding	encode	VBG
cord-260708-l9w5jhsw	108	29	a	a	DT
cord-260708-l9w5jhsw	108	30	polyprotein	polyprotein	NN
cord-260708-l9w5jhsw	108	31	that	that	WDT
cord-260708-l9w5jhsw	108	32	is	be	VBZ
cord-260708-l9w5jhsw	108	33	co	co	JJ
cord-260708-l9w5jhsw	108	34	-	-	JJ
cord-260708-l9w5jhsw	108	35	and	and	CC
cord-260708-l9w5jhsw	108	36	post	post	VB
cord-260708-l9w5jhsw	108	37	-	-	NN
cord-260708-l9w5jhsw	108	38	translationally	translationally	RB
cord-260708-l9w5jhsw	108	39	cleaved	cleave	VBN
cord-260708-l9w5jhsw	108	40	into	into	IN
cord-260708-l9w5jhsw	108	41	the	the	DT
cord-260708-l9w5jhsw	108	42	mature	mature	JJ
cord-260708-l9w5jhsw	108	43	viral	viral	JJ
cord-260708-l9w5jhsw	108	44	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	108	45	[	[	-LRB-
cord-260708-l9w5jhsw	108	46	39	39	CD
cord-260708-l9w5jhsw	108	47	]	]	-RRB-
cord-260708-l9w5jhsw	108	48	.	.	.
cord-260708-l9w5jhsw	109	1	The	the	DT
cord-260708-l9w5jhsw	109	2	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	109	3	of	of	IN
cord-260708-l9w5jhsw	109	4	most	most	JJS
cord-260708-l9w5jhsw	109	5	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	109	6	are	be	VBP
cord-260708-l9w5jhsw	109	7	still	still	RB
cord-260708-l9w5jhsw	109	8	poorly	poorly	RB
cord-260708-l9w5jhsw	109	9	characterised	characterise	VBN
cord-260708-l9w5jhsw	109	10	,	,	,
cord-260708-l9w5jhsw	109	11	and	and	CC
cord-260708-l9w5jhsw	109	12	most	most	JJS
cord-260708-l9w5jhsw	109	13	of	of	IN
cord-260708-l9w5jhsw	109	14	the	the	DT
cord-260708-l9w5jhsw	109	15	available	available	JJ
cord-260708-l9w5jhsw	109	16	data	datum	NNS
cord-260708-l9w5jhsw	109	17	come	come	VBP
cord-260708-l9w5jhsw	109	18	from	from	IN
cord-260708-l9w5jhsw	109	19	studies	study	NNS
cord-260708-l9w5jhsw	109	20	on	on	IN
cord-260708-l9w5jhsw	109	21	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	109	22	,	,	,
cord-260708-l9w5jhsw	109	23	largely	largely	RB
cord-260708-l9w5jhsw	109	24	through	through	IN
cord-260708-l9w5jhsw	109	25	studies	study	NNS
cord-260708-l9w5jhsw	109	26	on	on	IN
cord-260708-l9w5jhsw	109	27	proteins	protein	NNS
cord-260708-l9w5jhsw	109	28	expressed	express	VBN
cord-260708-l9w5jhsw	109	29	from	from	IN
cord-260708-l9w5jhsw	109	30	plasmids	plasmid	NNS
cord-260708-l9w5jhsw	109	31	.	.	.
cord-260708-l9w5jhsw	110	1	The	the	DT
cord-260708-l9w5jhsw	110	2	processing	processing	NN
cord-260708-l9w5jhsw	110	3	of	of	IN
cord-260708-l9w5jhsw	110	4	the	the	DT
cord-260708-l9w5jhsw	110	5	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	110	6	M	M	NNP
cord-260708-l9w5jhsw	110	7	polyprotein	polyprotein	NN
cord-260708-l9w5jhsw	110	8	to	to	TO
cord-260708-l9w5jhsw	110	9	generate	generate	VB
cord-260708-l9w5jhsw	110	10	the	the	DT
cord-260708-l9w5jhsw	110	11	mature	mature	JJ
cord-260708-l9w5jhsw	110	12	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	110	13	appears	appear	VBZ
cord-260708-l9w5jhsw	110	14	to	to	TO
cord-260708-l9w5jhsw	110	15	be	be	VB
cord-260708-l9w5jhsw	110	16	more	more	RBR
cord-260708-l9w5jhsw	110	17	complex	complex	JJ
cord-260708-l9w5jhsw	110	18	than	than	IN
cord-260708-l9w5jhsw	110	19	that	that	DT
cord-260708-l9w5jhsw	110	20	of	of	IN
cord-260708-l9w5jhsw	110	21	other	other	JJ
cord-260708-l9w5jhsw	110	22	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	110	23	,	,	,
cord-260708-l9w5jhsw	110	24	as	as	IN
cord-260708-l9w5jhsw	110	25	it	-PRON-	PRP
cord-260708-l9w5jhsw	110	26	involves	involve	VBZ
cord-260708-l9w5jhsw	110	27	first	first	RB
cord-260708-l9w5jhsw	110	28	the	the	DT
cord-260708-l9w5jhsw	110	29	generation	generation	NN
cord-260708-l9w5jhsw	110	30	of	of	IN
cord-260708-l9w5jhsw	110	31	glycoprotein	glycoprotein	NN
cord-260708-l9w5jhsw	110	32	precursors	precursor	NNS
cord-260708-l9w5jhsw	110	33	through	through	IN
cord-260708-l9w5jhsw	110	34	the	the	DT
cord-260708-l9w5jhsw	110	35	action	action	NN
cord-260708-l9w5jhsw	110	36	of	of	IN
cord-260708-l9w5jhsw	110	37	the	the	DT
cord-260708-l9w5jhsw	110	38	signal	signal	NN
cord-260708-l9w5jhsw	110	39	protease	protease	NN
cord-260708-l9w5jhsw	110	40	in	in	IN
cord-260708-l9w5jhsw	110	41	the	the	DT
cord-260708-l9w5jhsw	110	42	endoplasmic	endoplasmic	NN
cord-260708-l9w5jhsw	110	43	reticulum	reticulum	NN
cord-260708-l9w5jhsw	110	44	(	(	-LRB-
cord-260708-l9w5jhsw	110	45	ER	ER	NNP
cord-260708-l9w5jhsw	110	46	)	)	-RRB-
cord-260708-l9w5jhsw	110	47	followed	follow	VBN
cord-260708-l9w5jhsw	110	48	by	by	IN
cord-260708-l9w5jhsw	110	49	further	further	JJ
cord-260708-l9w5jhsw	110	50	cleavages	cleavage	NNS
cord-260708-l9w5jhsw	110	51	to	to	TO
cord-260708-l9w5jhsw	110	52	give	give	VB
cord-260708-l9w5jhsw	110	53	rise	rise	NN
cord-260708-l9w5jhsw	110	54	to	to	IN
cord-260708-l9w5jhsw	110	55	the	the	DT
cord-260708-l9w5jhsw	110	56	full	full	JJ
cord-260708-l9w5jhsw	110	57	set	set	NN
cord-260708-l9w5jhsw	110	58	of	of	IN
cord-260708-l9w5jhsw	110	59	mature	mature	JJ
cord-260708-l9w5jhsw	110	60	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	110	61	,	,	,
cord-260708-l9w5jhsw	110	62	a	a	DT
cord-260708-l9w5jhsw	110	63	process	process	NN
cord-260708-l9w5jhsw	110	64	that	that	WDT
cord-260708-l9w5jhsw	110	65	employs	employ	VBZ
cord-260708-l9w5jhsw	110	66	other	other	JJ
cord-260708-l9w5jhsw	110	67	cellular	cellular	JJ
cord-260708-l9w5jhsw	110	68	proteases	protease	NNS
cord-260708-l9w5jhsw	110	69	[	[	-LRB-
cord-260708-l9w5jhsw	110	70	15	15	CD
cord-260708-l9w5jhsw	110	71	,	,	,
cord-260708-l9w5jhsw	110	72	144	144	CD
cord-260708-l9w5jhsw	110	73	,	,	,
cord-260708-l9w5jhsw	110	74	145	145	CD
cord-260708-l9w5jhsw	110	75	,	,	,
cord-260708-l9w5jhsw	110	76	172	172	CD
cord-260708-l9w5jhsw	110	77	]	]	-RRB-
cord-260708-l9w5jhsw	111	1	(	(	-LRB-
cord-260708-l9w5jhsw	111	2	Fig	Fig	NNP
cord-260708-l9w5jhsw	111	3	.	.	.
cord-260708-l9w5jhsw	111	4	3	3	CD
cord-260708-l9w5jhsw	111	5	)	)	-RRB-
cord-260708-l9w5jhsw	111	6	.	.	.
cord-260708-l9w5jhsw	112	1	The	the	DT
cord-260708-l9w5jhsw	112	2	virions	virion	NNS
cord-260708-l9w5jhsw	112	3	of	of	IN
cord-260708-l9w5jhsw	112	4	most	most	JJS
cord-260708-l9w5jhsw	112	5	of	of	IN
cord-260708-l9w5jhsw	112	6	the	the	DT
cord-260708-l9w5jhsw	112	7	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	112	8	contain	contain	VBP
cord-260708-l9w5jhsw	112	9	two	two	CD
cord-260708-l9w5jhsw	112	10	mature	mature	JJ
cord-260708-l9w5jhsw	112	11	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	112	12	,	,	,
cord-260708-l9w5jhsw	112	13	Gn	Gn	NNP
cord-260708-l9w5jhsw	112	14	and	and	CC
cord-260708-l9w5jhsw	112	15	Gc	Gc	NNP
cord-260708-l9w5jhsw	112	16	[	[	-LRB-
cord-260708-l9w5jhsw	112	17	15	15	CD
cord-260708-l9w5jhsw	112	18	,	,	,
cord-260708-l9w5jhsw	112	19	33	33	CD
cord-260708-l9w5jhsw	112	20	,	,	,
cord-260708-l9w5jhsw	112	21	38	38	CD
cord-260708-l9w5jhsw	112	22	,	,	,
cord-260708-l9w5jhsw	112	23	107	107	CD
cord-260708-l9w5jhsw	112	24	,	,	,
cord-260708-l9w5jhsw	112	25	144	144	CD
cord-260708-l9w5jhsw	112	26	,	,	,
cord-260708-l9w5jhsw	112	27	145	145	CD
cord-260708-l9w5jhsw	112	28	,	,	,
cord-260708-l9w5jhsw	112	29	172	172	CD
cord-260708-l9w5jhsw	112	30	]	]	-RRB-
cord-260708-l9w5jhsw	112	31	;	;	:
cord-260708-l9w5jhsw	112	32	however	however	RB
cord-260708-l9w5jhsw	112	33	,	,	,
cord-260708-l9w5jhsw	112	34	two	two	CD
cord-260708-l9w5jhsw	112	35	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	112	36	,	,	,
cord-260708-l9w5jhsw	112	37	Hazara	hazara	JJ
cord-260708-l9w5jhsw	112	38	virus	virus	NN
cord-260708-l9w5jhsw	112	39	and	and	CC
cord-260708-l9w5jhsw	112	40	Clo	Clo	NNP
cord-260708-l9w5jhsw	112	41	Mor	Mor	NNP
cord-260708-l9w5jhsw	112	42	virus	virus	NN
cord-260708-l9w5jhsw	112	43	,	,	,
cord-260708-l9w5jhsw	112	44	have	have	VBP
cord-260708-l9w5jhsw	112	45	been	be	VBN
cord-260708-l9w5jhsw	112	46	shown	show	VBN
cord-260708-l9w5jhsw	112	47	to	to	TO
cord-260708-l9w5jhsw	112	48	contain	contain	VB
cord-260708-l9w5jhsw	112	49	three	three	CD
cord-260708-l9w5jhsw	112	50	structural	structural	JJ
cord-260708-l9w5jhsw	112	51	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	112	52	[	[	-LRB-
cord-260708-l9w5jhsw	112	53	68	68	CD
cord-260708-l9w5jhsw	112	54	,	,	,
cord-260708-l9w5jhsw	112	55	175	175	CD
cord-260708-l9w5jhsw	112	56	]	]	-RRB-
cord-260708-l9w5jhsw	112	57	.	.	.
cord-260708-l9w5jhsw	113	1	The	the	DT
cord-260708-l9w5jhsw	113	2	full	full	JJ
cord-260708-l9w5jhsw	113	3	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	113	4	M	M	NNP
cord-260708-l9w5jhsw	113	5	-	-	HYPH
cord-260708-l9w5jhsw	113	6	encoded	encode	VBN
cord-260708-l9w5jhsw	113	7	polyprotein	polyprotein	NN
cord-260708-l9w5jhsw	113	8	appears	appear	VBZ
cord-260708-l9w5jhsw	113	9	to	to	TO
cord-260708-l9w5jhsw	113	10	have	have	VB
cord-260708-l9w5jhsw	113	11	six	six	CD
cord-260708-l9w5jhsw	113	12	hydrophobic	hydrophobic	JJ
cord-260708-l9w5jhsw	113	13	regions	region	NNS
cord-260708-l9w5jhsw	113	14	(	(	-LRB-
cord-260708-l9w5jhsw	113	15	TM	TM	NNP
cord-260708-l9w5jhsw	113	16	0	0	CD
cord-260708-l9w5jhsw	113	17	-TM	-tm	SYM
cord-260708-l9w5jhsw	113	18	5	5	CD
cord-260708-l9w5jhsw	113	19	)	)	-RRB-
cord-260708-l9w5jhsw	113	20	,	,	,
cord-260708-l9w5jhsw	113	21	which	which	WDT
cord-260708-l9w5jhsw	113	22	could	could	MD
cord-260708-l9w5jhsw	113	23	function	function	VB
cord-260708-l9w5jhsw	113	24	as	as	IN
cord-260708-l9w5jhsw	113	25	transmembrane	transmembrane	NNP
cord-260708-l9w5jhsw	113	26	helices	helix	NNS
cord-260708-l9w5jhsw	113	27	[	[	-LRB-
cord-260708-l9w5jhsw	113	28	3	3	CD
cord-260708-l9w5jhsw	113	29	,	,	,
cord-260708-l9w5jhsw	113	30	144	144	CD
cord-260708-l9w5jhsw	113	31	]	]	-RRB-
cord-260708-l9w5jhsw	113	32	and	and	CC
cord-260708-l9w5jhsw	113	33	act	act	VBP
cord-260708-l9w5jhsw	113	34	either	either	CC
cord-260708-l9w5jhsw	113	35	as	as	IN
cord-260708-l9w5jhsw	113	36	classic	classic	JJ
cord-260708-l9w5jhsw	113	37	secretory	secretory	JJ
cord-260708-l9w5jhsw	113	38	signal	signal	NN
cord-260708-l9w5jhsw	113	39	peptides	peptide	NNS
cord-260708-l9w5jhsw	113	40	(	(	-LRB-
cord-260708-l9w5jhsw	113	41	TM	TM	NNP
cord-260708-l9w5jhsw	113	42	0	0	CD
cord-260708-l9w5jhsw	113	43	)	)	-RRB-
cord-260708-l9w5jhsw	113	44	,	,	,
cord-260708-l9w5jhsw	113	45	membrane	membrane	NN
cord-260708-l9w5jhsw	113	46	anchors	anchor	NNS
cord-260708-l9w5jhsw	113	47	(	(	-LRB-
cord-260708-l9w5jhsw	113	48	TM	TM	NNP
cord-260708-l9w5jhsw	113	49	1	1	CD
cord-260708-l9w5jhsw	113	50	,	,	,
cord-260708-l9w5jhsw	113	51	3	3	CD
cord-260708-l9w5jhsw	113	52	and	and	CC
cord-260708-l9w5jhsw	113	53	5	5	CD
cord-260708-l9w5jhsw	113	54	)	)	-RRB-
cord-260708-l9w5jhsw	113	55	,	,	,
cord-260708-l9w5jhsw	113	56	or	or	CC
cord-260708-l9w5jhsw	113	57	a	a	DT
cord-260708-l9w5jhsw	113	58	combination	combination	NN
cord-260708-l9w5jhsw	113	59	of	of	IN
cord-260708-l9w5jhsw	113	60	both	both	DT
cord-260708-l9w5jhsw	113	61	(	(	-LRB-
cord-260708-l9w5jhsw	113	62	TM	TM	NNP
cord-260708-l9w5jhsw	113	63	2,4	2,4	CD
cord-260708-l9w5jhsw	113	64	)	)	-RRB-
cord-260708-l9w5jhsw	114	1	(	(	-LRB-
cord-260708-l9w5jhsw	114	2	Fig	Fig	NNP
cord-260708-l9w5jhsw	114	3	.	.	.
cord-260708-l9w5jhsw	114	4	3	3	CD
cord-260708-l9w5jhsw	114	5	)	)	-RRB-
cord-260708-l9w5jhsw	114	6	.	.	.
cord-260708-l9w5jhsw	115	1	Signal	signal	NN
cord-260708-l9w5jhsw	115	2	cleavage	cleavage	NN
cord-260708-l9w5jhsw	115	3	motifs	motif	NNS
cord-260708-l9w5jhsw	115	4	are	be	VBP
cord-260708-l9w5jhsw	115	5	found	find	VBN
cord-260708-l9w5jhsw	115	6	after	after	IN
cord-260708-l9w5jhsw	115	7	TM	TM	NNP
cord-260708-l9w5jhsw	115	8	0	0	NFP
cord-260708-l9w5jhsw	115	9	(	(	-LRB-
cord-260708-l9w5jhsw	115	10	releasing	release	VBG
cord-260708-l9w5jhsw	115	11	the	the	DT
cord-260708-l9w5jhsw	115	12	amino	amino	NN
cord-260708-l9w5jhsw	115	13	terminus	terminus	NN
cord-260708-l9w5jhsw	115	14	of	of	IN
cord-260708-l9w5jhsw	115	15	the	the	DT
cord-260708-l9w5jhsw	115	16	Gn	Gn	NNP
cord-260708-l9w5jhsw	115	17	precursor	precursor	NN
cord-260708-l9w5jhsw	115	18	,	,	,
cord-260708-l9w5jhsw	115	19	PreGn	PreGn	NNP
cord-260708-l9w5jhsw	115	20	)	)	-RRB-
cord-260708-l9w5jhsw	115	21	and	and	CC
cord-260708-l9w5jhsw	115	22	TM	TM	NNP
cord-260708-l9w5jhsw	115	23	4	4	CD
cord-260708-l9w5jhsw	115	24	(	(	-LRB-
cord-260708-l9w5jhsw	115	25	releasing	release	VBG
cord-260708-l9w5jhsw	115	26	the	the	DT
cord-260708-l9w5jhsw	115	27	Gc	Gc	NNP
cord-260708-l9w5jhsw	115	28	precursor	precursor	NN
cord-260708-l9w5jhsw	115	29	PreGc	PreGc	NNP
cord-260708-l9w5jhsw	115	30	)	)	-RRB-
cord-260708-l9w5jhsw	115	31	.	.	.
cord-260708-l9w5jhsw	116	1	Sequence	sequence	NN
cord-260708-l9w5jhsw	116	2	inspection	inspection	NN
cord-260708-l9w5jhsw	116	3	revealed	reveal	VBD
cord-260708-l9w5jhsw	116	4	a	a	DT
cord-260708-l9w5jhsw	116	5	signal	signal	NN
cord-260708-l9w5jhsw	116	6	cleavage	cleavage	NN
cord-260708-l9w5jhsw	116	7	signal	signal	NN
cord-260708-l9w5jhsw	116	8	immediately	immediately	RB
cord-260708-l9w5jhsw	116	9	after	after	IN
cord-260708-l9w5jhsw	116	10	TM	TM	NNP
cord-260708-l9w5jhsw	116	11	2	2	CD
cord-260708-l9w5jhsw	116	12	,	,	,
cord-260708-l9w5jhsw	116	13	suggesting	suggest	VBG
cord-260708-l9w5jhsw	116	14	that	that	IN
cord-260708-l9w5jhsw	116	15	there	there	EX
cord-260708-l9w5jhsw	116	16	might	may	MD
cord-260708-l9w5jhsw	116	17	be	be	VB
cord-260708-l9w5jhsw	116	18	a	a	DT
cord-260708-l9w5jhsw	116	19	separate	separate	JJ
cord-260708-l9w5jhsw	116	20	protein	protein	NN
cord-260708-l9w5jhsw	116	21	released	release	VBN
cord-260708-l9w5jhsw	116	22	,	,	,
cord-260708-l9w5jhsw	116	23	consisting	consist	VBG
cord-260708-l9w5jhsw	116	24	of	of	IN
cord-260708-l9w5jhsw	116	25	the	the	DT
cord-260708-l9w5jhsw	116	26	sequence	sequence	NN
cord-260708-l9w5jhsw	116	27	between	between	IN
cord-260708-l9w5jhsw	116	28	the	the	DT
cord-260708-l9w5jhsw	116	29	distal	distal	JJ
cord-260708-l9w5jhsw	116	30	ends	end	NNS
cord-260708-l9w5jhsw	116	31	of	of	IN
cord-260708-l9w5jhsw	116	32	TM	TM	NNP
cord-260708-l9w5jhsw	116	33	2	2	CD
cord-260708-l9w5jhsw	116	34	and	and	CC
cord-260708-l9w5jhsw	116	35	TM	TM	NNP
cord-260708-l9w5jhsw	116	36	4	4	CD
cord-260708-l9w5jhsw	116	37	;	;	:
cord-260708-l9w5jhsw	116	38	such	such	PDT
cord-260708-l9w5jhsw	116	39	a	a	DT
cord-260708-l9w5jhsw	116	40	protein	protein	NN
cord-260708-l9w5jhsw	116	41	has	have	VBZ
cord-260708-l9w5jhsw	116	42	been	be	VBN
cord-260708-l9w5jhsw	116	43	shown	show	VBN
cord-260708-l9w5jhsw	116	44	to	to	TO
cord-260708-l9w5jhsw	116	45	be	be	VB
cord-260708-l9w5jhsw	116	46	produced	produce	VBN
cord-260708-l9w5jhsw	116	47	by	by	IN
cord-260708-l9w5jhsw	116	48	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	116	49	and	and	CC
cord-260708-l9w5jhsw	116	50	has	have	VBZ
cord-260708-l9w5jhsw	116	51	been	be	VBN
cord-260708-l9w5jhsw	116	52	termed	term	VBN
cord-260708-l9w5jhsw	116	53	NS	NS	NNP
cord-260708-l9w5jhsw	116	54	M	M	NNP
cord-260708-l9w5jhsw	116	55	[	[	-LRB-
cord-260708-l9w5jhsw	116	56	3	3	CD
cord-260708-l9w5jhsw	116	57	]	]	-RRB-
cord-260708-l9w5jhsw	116	58	.	.	.
cord-260708-l9w5jhsw	117	1	Further	further	JJ
cord-260708-l9w5jhsw	117	2	non	non	JJ
cord-260708-l9w5jhsw	117	3	-	-	JJ
cord-260708-l9w5jhsw	117	4	structural	structural	JJ
cord-260708-l9w5jhsw	117	5	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	117	6	have	have	VBP
cord-260708-l9w5jhsw	117	7	been	be	VBN
cord-260708-l9w5jhsw	117	8	identified	identify	VBN
cord-260708-l9w5jhsw	117	9	in	in	IN
cord-260708-l9w5jhsw	117	10	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	117	11	-	-	HYPH
cord-260708-l9w5jhsw	117	12	infected	infect	VBN
cord-260708-l9w5jhsw	117	13	cells	cell	NNS
cord-260708-l9w5jhsw	117	14	,	,	,
cord-260708-l9w5jhsw	117	15	referred	refer	VBD
cord-260708-l9w5jhsw	117	16	to	to	IN
cord-260708-l9w5jhsw	117	17	as	as	IN
cord-260708-l9w5jhsw	117	18	the	the	DT
cord-260708-l9w5jhsw	117	19	mucin	mucin	NN
cord-260708-l9w5jhsw	117	20	-	-	HYPH
cord-260708-l9w5jhsw	117	21	like	like	JJ
cord-260708-l9w5jhsw	117	22	domain	domain	NN
cord-260708-l9w5jhsw	117	23	(	(	-LRB-
cord-260708-l9w5jhsw	117	24	a	a	DT
cord-260708-l9w5jhsw	117	25	highly	highly	RB
cord-260708-l9w5jhsw	117	26	O	o	NN
cord-260708-l9w5jhsw	117	27	-	-	HYPH
cord-260708-l9w5jhsw	117	28	glycosylated	glycosylate	VBN
cord-260708-l9w5jhsw	117	29	peptide	peptide	NN
cord-260708-l9w5jhsw	117	30	)	)	-RRB-
cord-260708-l9w5jhsw	117	31	,	,	,
cord-260708-l9w5jhsw	117	32	GP38	GP38	NNP
cord-260708-l9w5jhsw	117	33	,	,	,
cord-260708-l9w5jhsw	117	34	GP85	GP85	NNP
cord-260708-l9w5jhsw	117	35	and	and	CC
cord-260708-l9w5jhsw	117	36	GP160	GP160	NNP
cord-260708-l9w5jhsw	117	37	,	,	,
cord-260708-l9w5jhsw	117	38	all	all	DT
cord-260708-l9w5jhsw	117	39	of	of	IN
cord-260708-l9w5jhsw	117	40	which	which	WDT
cord-260708-l9w5jhsw	117	41	are	be	VBP
cord-260708-l9w5jhsw	117	42	released	release	VBN
cord-260708-l9w5jhsw	117	43	from	from	IN
cord-260708-l9w5jhsw	117	44	infected	infected	JJ
cord-260708-l9w5jhsw	117	45	cells	cell	NNS
cord-260708-l9w5jhsw	117	46	;	;	:
cord-260708-l9w5jhsw	117	47	GP85	GP85	NNP
cord-260708-l9w5jhsw	117	48	and	and	CC
cord-260708-l9w5jhsw	117	49	GP160	GP160	NNP
cord-260708-l9w5jhsw	117	50	contain	contain	VBP
cord-260708-l9w5jhsw	117	51	both	both	CC
cord-260708-l9w5jhsw	117	52	the	the	DT
cord-260708-l9w5jhsw	117	53	GP38	GP38	NNP
cord-260708-l9w5jhsw	117	54	protein	protein	NN
cord-260708-l9w5jhsw	117	55	and	and	CC
cord-260708-l9w5jhsw	117	56	the	the	DT
cord-260708-l9w5jhsw	117	57	mucin	mucin	NN
cord-260708-l9w5jhsw	117	58	-	-	HYPH
cord-260708-l9w5jhsw	117	59	like	like	JJ
cord-260708-l9w5jhsw	117	60	domain	domain	NN
cord-260708-l9w5jhsw	117	61	[	[	-LRB-
cord-260708-l9w5jhsw	117	62	145	145	CD
cord-260708-l9w5jhsw	117	63	]	]	-RRB-
cord-260708-l9w5jhsw	117	64	.	.	.
cord-260708-l9w5jhsw	118	1	A	a	DT
cord-260708-l9w5jhsw	118	2	model	model	NN
cord-260708-l9w5jhsw	118	3	for	for	IN
cord-260708-l9w5jhsw	118	4	the	the	DT
cord-260708-l9w5jhsw	118	5	generation	generation	NN
cord-260708-l9w5jhsw	118	6	of	of	IN
cord-260708-l9w5jhsw	118	7	the	the	DT
cord-260708-l9w5jhsw	118	8	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	118	9	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	118	10	is	be	VBZ
cord-260708-l9w5jhsw	118	11	summarised	summarise	VBN
cord-260708-l9w5jhsw	118	12	in	in	IN
cord-260708-l9w5jhsw	118	13	Figure	Figure	NNP
cord-260708-l9w5jhsw	118	14	3	3	CD
cord-260708-l9w5jhsw	118	15	based	base	VBN
cord-260708-l9w5jhsw	118	16	on	on	IN
cord-260708-l9w5jhsw	118	17	a	a	DT
cord-260708-l9w5jhsw	118	18	number	number	NN
cord-260708-l9w5jhsw	118	19	of	of	IN
cord-260708-l9w5jhsw	118	20	studies	study	NNS
cord-260708-l9w5jhsw	118	21	[	[	-LRB-
cord-260708-l9w5jhsw	118	22	3	3	CD
cord-260708-l9w5jhsw	118	23	,	,	,
cord-260708-l9w5jhsw	118	24	144	144	CD
cord-260708-l9w5jhsw	118	25	,	,	,
cord-260708-l9w5jhsw	118	26	145	145	CD
cord-260708-l9w5jhsw	118	27	,	,	,
cord-260708-l9w5jhsw	118	28	172	172	CD
cord-260708-l9w5jhsw	118	29	]	]	-RRB-
cord-260708-l9w5jhsw	118	30	.	.	.
cord-260708-l9w5jhsw	119	1	Co	co	JJ
cord-260708-l9w5jhsw	119	2	-	-	JJ
cord-260708-l9w5jhsw	119	3	translational	translational	JJ
cord-260708-l9w5jhsw	119	4	cleavage	cleavage	NN
cord-260708-l9w5jhsw	119	5	in	in	IN
cord-260708-l9w5jhsw	119	6	the	the	DT
cord-260708-l9w5jhsw	119	7	ER	ER	NNP
cord-260708-l9w5jhsw	119	8	by	by	IN
cord-260708-l9w5jhsw	119	9	cellular	cellular	JJ
cord-260708-l9w5jhsw	119	10	signalase	signalase	NN
cord-260708-l9w5jhsw	119	11	generates	generate	VBZ
cord-260708-l9w5jhsw	119	12	the	the	DT
cord-260708-l9w5jhsw	119	13	140-kDa	140-kda	CD
cord-260708-l9w5jhsw	120	1	PreGn	pregn	PRP
cord-260708-l9w5jhsw	121	1	(	(	-LRB-
cord-260708-l9w5jhsw	121	2	containing	contain	VBG
cord-260708-l9w5jhsw	121	3	the	the	DT
cord-260708-l9w5jhsw	121	4	mucin	mucin	NN
cord-260708-l9w5jhsw	121	5	-	-	HYPH
cord-260708-l9w5jhsw	121	6	like	like	JJ
cord-260708-l9w5jhsw	121	7	domain	domain	NN
cord-260708-l9w5jhsw	121	8	,	,	,
cord-260708-l9w5jhsw	121	9	GP38	GP38	NNP
cord-260708-l9w5jhsw	121	10	,	,	,
cord-260708-l9w5jhsw	121	11	and	and	CC
cord-260708-l9w5jhsw	121	12	Gn	Gn	NNP
cord-260708-l9w5jhsw	121	13	)	)	-RRB-
cord-260708-l9w5jhsw	121	14	,	,	,
cord-260708-l9w5jhsw	121	15	the	the	DT
cord-260708-l9w5jhsw	121	16	predominantly	predominantly	RB
cord-260708-l9w5jhsw	121	17	cytoplasmically	cytoplasmically	RB
cord-260708-l9w5jhsw	121	18	oriented	orient	VBN
cord-260708-l9w5jhsw	121	19	NS	NS	NNP
cord-260708-l9w5jhsw	121	20	M	M	NNP
cord-260708-l9w5jhsw	121	21	,	,	,
cord-260708-l9w5jhsw	121	22	and	and	CC
cord-260708-l9w5jhsw	121	23	the	the	DT
cord-260708-l9w5jhsw	121	24	85-kDa	85-kda	CD
cord-260708-l9w5jhsw	122	1	PreGc	PreGc	NNP
cord-260708-l9w5jhsw	122	2	.	.	.
cord-260708-l9w5jhsw	123	1	The	the	DT
cord-260708-l9w5jhsw	123	2	PreGn	pregn	NN
cord-260708-l9w5jhsw	123	3	is	be	VBZ
cord-260708-l9w5jhsw	123	4	further	further	RB
cord-260708-l9w5jhsw	123	5	cleaved	cleave	VBN
cord-260708-l9w5jhsw	123	6	,	,	,
cord-260708-l9w5jhsw	123	7	either	either	CC
cord-260708-l9w5jhsw	123	8	in	in	IN
cord-260708-l9w5jhsw	123	9	the	the	DT
cord-260708-l9w5jhsw	123	10	ER	ER	NNP
cord-260708-l9w5jhsw	123	11	or	or	CC
cord-260708-l9w5jhsw	123	12	the	the	DT
cord-260708-l9w5jhsw	123	13	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	123	14	compartment	compartment	NN
cord-260708-l9w5jhsw	123	15	,	,	,
cord-260708-l9w5jhsw	123	16	to	to	TO
cord-260708-l9w5jhsw	123	17	separate	separate	VB
cord-260708-l9w5jhsw	123	18	mucin	mucin	NN
cord-260708-l9w5jhsw	123	19	-	-	HYPH
cord-260708-l9w5jhsw	123	20	like	like	JJ
cord-260708-l9w5jhsw	123	21	domain/	domain/	ADD
cord-260708-l9w5jhsw	124	1	GP38	GP38	NNP
cord-260708-l9w5jhsw	124	2	from	from	IN
cord-260708-l9w5jhsw	124	3	[	[	-LRB-
cord-260708-l9w5jhsw	124	4	4	4	CD
cord-260708-l9w5jhsw	124	5	,	,	,
cord-260708-l9w5jhsw	124	6	161	161	CD
cord-260708-l9w5jhsw	124	7	,	,	,
cord-260708-l9w5jhsw	124	8	162	162	CD
cord-260708-l9w5jhsw	124	9	]	]	-RRB-
cord-260708-l9w5jhsw	124	10	Gn	Gn	NNP
cord-260708-l9w5jhsw	124	11	.	.	.
cord-260708-l9w5jhsw	125	1	This	this	DT
cord-260708-l9w5jhsw	125	2	cleavage	cleavage	NN
cord-260708-l9w5jhsw	125	3	occurs	occur	VBZ
cord-260708-l9w5jhsw	125	4	at	at	IN
cord-260708-l9w5jhsw	125	5	a	a	DT
cord-260708-l9w5jhsw	125	6	conserved	conserve	VBN
cord-260708-l9w5jhsw	125	7	RRLL	rrll	NN
cord-260708-l9w5jhsw	125	8	;	;	,
cord-260708-l9w5jhsw	125	9	motif	motif	NN
cord-260708-l9w5jhsw	125	10	and	and	CC
cord-260708-l9w5jhsw	125	11	is	be	VBZ
cord-260708-l9w5jhsw	125	12	effected	effect	VBN
cord-260708-l9w5jhsw	125	13	by	by	IN
cord-260708-l9w5jhsw	125	14	the	the	DT
cord-260708-l9w5jhsw	125	15	host	host	NN
cord-260708-l9w5jhsw	125	16	's	's	POS
cord-260708-l9w5jhsw	125	17	subtilisin	subtilisin	NNP
cord-260708-l9w5jhsw	125	18	kexin	kexin	NNP
cord-260708-l9w5jhsw	125	19	isozyme-1	isozyme-1	NNP
cord-260708-l9w5jhsw	125	20	/	/	SYM
cord-260708-l9w5jhsw	125	21	site-1	site-1	NNP
cord-260708-l9w5jhsw	125	22	protease	protease	NN
cord-260708-l9w5jhsw	125	23	(	(	-LRB-
cord-260708-l9w5jhsw	125	24	SKI-1	SKI-1	NNP
cord-260708-l9w5jhsw	125	25	/	/	SYM
cord-260708-l9w5jhsw	125	26	S1P	s1p	NN
cord-260708-l9w5jhsw	125	27	)	)	-RRB-
cord-260708-l9w5jhsw	125	28	[	[	-LRB-
cord-260708-l9w5jhsw	125	29	145	145	CD
cord-260708-l9w5jhsw	125	30	,	,	,
cord-260708-l9w5jhsw	125	31	172	172	CD
cord-260708-l9w5jhsw	125	32	]	]	-RRB-
cord-260708-l9w5jhsw	125	33	.	.	.
cord-260708-l9w5jhsw	126	1	This	this	DT
cord-260708-l9w5jhsw	126	2	cleavage	cleavage	NN
cord-260708-l9w5jhsw	126	3	has	have	VBZ
cord-260708-l9w5jhsw	126	4	been	be	VBN
cord-260708-l9w5jhsw	126	5	shown	show	VBN
cord-260708-l9w5jhsw	126	6	to	to	TO
cord-260708-l9w5jhsw	126	7	be	be	VB
cord-260708-l9w5jhsw	126	8	critical	critical	JJ
cord-260708-l9w5jhsw	126	9	for	for	IN
cord-260708-l9w5jhsw	126	10	virus	virus	NN
cord-260708-l9w5jhsw	126	11	replication	replication	NN
cord-260708-l9w5jhsw	126	12	and	and	CC
cord-260708-l9w5jhsw	126	13	subsequent	subsequent	JJ
cord-260708-l9w5jhsw	126	14	infectivity	infectivity	NN
cord-260708-l9w5jhsw	126	15	,	,	,
cord-260708-l9w5jhsw	126	16	and	and	CC
cord-260708-l9w5jhsw	126	17	lack	lack	NN
cord-260708-l9w5jhsw	126	18	of	of	IN
cord-260708-l9w5jhsw	126	19	the	the	DT
cord-260708-l9w5jhsw	126	20	cleavage	cleavage	NN
cord-260708-l9w5jhsw	126	21	prevents	prevent	VBZ
cord-260708-l9w5jhsw	126	22	incorporation	incorporation	NN
cord-260708-l9w5jhsw	126	23	of	of	IN
cord-260708-l9w5jhsw	126	24	the	the	DT
cord-260708-l9w5jhsw	126	25	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	126	26	into	into	IN
cord-260708-l9w5jhsw	126	27	viral	viral	JJ
cord-260708-l9w5jhsw	126	28	particles	particle	NNS
cord-260708-l9w5jhsw	126	29	[	[	-LRB-
cord-260708-l9w5jhsw	126	30	15	15	CD
cord-260708-l9w5jhsw	126	31	]	]	-RRB-
cord-260708-l9w5jhsw	126	32	.	.	.
cord-260708-l9w5jhsw	127	1	A	a	DT
cord-260708-l9w5jhsw	127	2	similar	similar	JJ
cord-260708-l9w5jhsw	127	3	tetrapeptide	tetrapeptide	NN
cord-260708-l9w5jhsw	127	4	(	(	-LRB-
cord-260708-l9w5jhsw	127	5	RKPL	RKPL	NNP
cord-260708-l9w5jhsw	127	6	)	)	-RRB-
cord-260708-l9w5jhsw	127	7	is	be	VBZ
cord-260708-l9w5jhsw	127	8	found	find	VBN
cord-260708-l9w5jhsw	127	9	41	41	CD
cord-260708-l9w5jhsw	127	10	amino	amino	JJ
cord-260708-l9w5jhsw	127	11	acids	acid	NNS
cord-260708-l9w5jhsw	127	12	downstream	downstream	RB
cord-260708-l9w5jhsw	127	13	of	of	IN
cord-260708-l9w5jhsw	127	14	the	the	DT
cord-260708-l9w5jhsw	127	15	signalase	signalase	NN
cord-260708-l9w5jhsw	127	16	cleavage	cleavage	NN
cord-260708-l9w5jhsw	127	17	site	site	NN
cord-260708-l9w5jhsw	127	18	in	in	IN
cord-260708-l9w5jhsw	127	19	PreGc	PreGc	NNP
cord-260708-l9w5jhsw	127	20	,	,	,
cord-260708-l9w5jhsw	127	21	which	which	WDT
cord-260708-l9w5jhsw	127	22	,	,	,
cord-260708-l9w5jhsw	127	23	although	although	IN
cord-260708-l9w5jhsw	127	24	it	-PRON-	PRP
cord-260708-l9w5jhsw	127	25	is	be	VBZ
cord-260708-l9w5jhsw	127	26	not	not	RB
cord-260708-l9w5jhsw	127	27	processed	process	VBN
cord-260708-l9w5jhsw	127	28	also	also	RB
cord-260708-l9w5jhsw	127	29	by	by	IN
cord-260708-l9w5jhsw	127	30	SKI-1	SKI-1	NNP
cord-260708-l9w5jhsw	127	31	/	/	SYM
cord-260708-l9w5jhsw	127	32	S1P	s1p	NN
cord-260708-l9w5jhsw	127	33	,	,	,
cord-260708-l9w5jhsw	127	34	is	be	VBZ
cord-260708-l9w5jhsw	127	35	predicted	predict	VBN
cord-260708-l9w5jhsw	127	36	to	to	TO
cord-260708-l9w5jhsw	127	37	be	be	VB
cord-260708-l9w5jhsw	127	38	utilised	utilise	VBN
cord-260708-l9w5jhsw	127	39	by	by	IN
cord-260708-l9w5jhsw	127	40	a	a	DT
cord-260708-l9w5jhsw	127	41	related	related	JJ
cord-260708-l9w5jhsw	127	42	subtilisin	subtilisin	NN
cord-260708-l9w5jhsw	127	43	-	-	HYPH
cord-260708-l9w5jhsw	127	44	like	like	JJ
cord-260708-l9w5jhsw	127	45	protease	protease	NN
cord-260708-l9w5jhsw	127	46	in	in	IN
cord-260708-l9w5jhsw	127	47	the	the	DT
cord-260708-l9w5jhsw	127	48	ER	ER	NNP
cord-260708-l9w5jhsw	127	49	/	/	SYM
cord-260708-l9w5jhsw	127	50	cis	cis	NNP
cord-260708-l9w5jhsw	127	51	-	-	HYPH
cord-260708-l9w5jhsw	127	52	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	127	53	to	to	TO
cord-260708-l9w5jhsw	127	54	generate	generate	VB
cord-260708-l9w5jhsw	127	55	the	the	DT
cord-260708-l9w5jhsw	127	56	mature	mature	JJ
cord-260708-l9w5jhsw	127	57	Gc	Gc	NNP
cord-260708-l9w5jhsw	127	58	(	(	-LRB-
cord-260708-l9w5jhsw	127	59	75	75	CD
cord-260708-l9w5jhsw	127	60	kDa	kDa	NNS
cord-260708-l9w5jhsw	127	61	)	)	-RRB-
cord-260708-l9w5jhsw	127	62	[	[	-LRB-
cord-260708-l9w5jhsw	127	63	144	144	CD
cord-260708-l9w5jhsw	127	64	,	,	,
cord-260708-l9w5jhsw	127	65	172	172	CD
cord-260708-l9w5jhsw	127	66	]	]	-RRB-
cord-260708-l9w5jhsw	127	67	.	.	.
cord-260708-l9w5jhsw	128	1	The	the	DT
cord-260708-l9w5jhsw	128	2	mature	mature	JJ
cord-260708-l9w5jhsw	128	3	Gn	Gn	NNP
cord-260708-l9w5jhsw	128	4	interacts	interact	VBZ
cord-260708-l9w5jhsw	128	5	(	(	-LRB-
cord-260708-l9w5jhsw	128	6	directly	directly	RB
cord-260708-l9w5jhsw	128	7	or	or	CC
cord-260708-l9w5jhsw	128	8	indirectly	indirectly	RB
cord-260708-l9w5jhsw	128	9	)	)	-RRB-
cord-260708-l9w5jhsw	128	10	with	with	IN
cord-260708-l9w5jhsw	128	11	the	the	DT
cord-260708-l9w5jhsw	128	12	Gc	Gc	NNP
cord-260708-l9w5jhsw	128	13	,	,	,
cord-260708-l9w5jhsw	128	14	and	and	CC
cord-260708-l9w5jhsw	128	15	both	both	DT
cord-260708-l9w5jhsw	128	16	are	be	VBP
cord-260708-l9w5jhsw	128	17	translocated	translocate	VBN
cord-260708-l9w5jhsw	128	18	to	to	IN
cord-260708-l9w5jhsw	128	19	the	the	DT
cord-260708-l9w5jhsw	128	20	virus	virus	NN
cord-260708-l9w5jhsw	128	21	-	-	HYPH
cord-260708-l9w5jhsw	128	22	assembly	assembly	NN
cord-260708-l9w5jhsw	128	23	sites	site	NNS
cord-260708-l9w5jhsw	128	24	in	in	IN
cord-260708-l9w5jhsw	128	25	the	the	DT
cord-260708-l9w5jhsw	128	26	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	128	27	[	[	-LRB-
cord-260708-l9w5jhsw	128	28	17	17	CD
cord-260708-l9w5jhsw	128	29	,	,	,
cord-260708-l9w5jhsw	128	30	59	59	CD
cord-260708-l9w5jhsw	128	31	,	,	,
cord-260708-l9w5jhsw	128	32	145	145	CD
cord-260708-l9w5jhsw	128	33	]	]	-RRB-
cord-260708-l9w5jhsw	128	34	.	.	.
cord-260708-l9w5jhsw	129	1	The	the	DT
cord-260708-l9w5jhsw	129	2	interaction	interaction	NN
cord-260708-l9w5jhsw	129	3	of	of	IN
cord-260708-l9w5jhsw	129	4	mature	mature	JJ
cord-260708-l9w5jhsw	129	5	Gn	Gn	NNP
cord-260708-l9w5jhsw	129	6	with	with	IN
cord-260708-l9w5jhsw	129	7	Gc	Gc	NNP
cord-260708-l9w5jhsw	129	8	is	be	VBZ
cord-260708-l9w5jhsw	129	9	essential	essential	JJ
cord-260708-l9w5jhsw	129	10	for	for	IN
cord-260708-l9w5jhsw	129	11	the	the	DT
cord-260708-l9w5jhsw	129	12	Gc	Gc	NNP
cord-260708-l9w5jhsw	129	13	to	to	TO
cord-260708-l9w5jhsw	129	14	travel	travel	VB
cord-260708-l9w5jhsw	129	15	from	from	IN
cord-260708-l9w5jhsw	129	16	ER	ER	NNP
cord-260708-l9w5jhsw	129	17	to	to	IN
cord-260708-l9w5jhsw	129	18	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	129	19	,	,	,
cord-260708-l9w5jhsw	129	20	as	as	IN
cord-260708-l9w5jhsw	129	21	Gn	Gn	NNP
cord-260708-l9w5jhsw	129	22	,	,	,
cord-260708-l9w5jhsw	129	23	but	but	CC
cord-260708-l9w5jhsw	129	24	not	not	RB
cord-260708-l9w5jhsw	129	25	Gc	Gc	NNP
cord-260708-l9w5jhsw	129	26	,	,	,
cord-260708-l9w5jhsw	129	27	contains	contain	VBZ
cord-260708-l9w5jhsw	129	28	a	a	DT
cord-260708-l9w5jhsw	129	29	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	129	30	localisation	localisation	NN
cord-260708-l9w5jhsw	129	31	signal	signal	NN
cord-260708-l9w5jhsw	129	32	[	[	-LRB-
cord-260708-l9w5jhsw	129	33	17	17	CD
cord-260708-l9w5jhsw	129	34	]	]	-RRB-
cord-260708-l9w5jhsw	129	35	.	.	.
cord-260708-l9w5jhsw	130	1	The	the	DT
cord-260708-l9w5jhsw	130	2	ectodomains	ectodomain	NNS
cord-260708-l9w5jhsw	130	3	of	of	IN
cord-260708-l9w5jhsw	130	4	Gn	Gn	NNP
cord-260708-l9w5jhsw	130	5	and	and	CC
cord-260708-l9w5jhsw	130	6	Gc	Gc	NNP
cord-260708-l9w5jhsw	130	7	appear	appear	VBP
cord-260708-l9w5jhsw	130	8	to	to	TO
cord-260708-l9w5jhsw	130	9	be	be	VB
cord-260708-l9w5jhsw	130	10	sufficient	sufficient	JJ
cord-260708-l9w5jhsw	130	11	for	for	IN
cord-260708-l9w5jhsw	130	12	heterodimer	heterodimer	NN
cord-260708-l9w5jhsw	130	13	formation	formation	NN
cord-260708-l9w5jhsw	130	14	and	and	CC
cord-260708-l9w5jhsw	130	15	transport	transport	NN
cord-260708-l9w5jhsw	130	16	to	to	IN
cord-260708-l9w5jhsw	130	17	the	the	DT
cord-260708-l9w5jhsw	130	18	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	130	19	,	,	,
cord-260708-l9w5jhsw	130	20	indicating	indicate	VBG
cord-260708-l9w5jhsw	130	21	that	that	IN
cord-260708-l9w5jhsw	130	22	at	at	IN
cord-260708-l9w5jhsw	130	23	least	least	JJS
cord-260708-l9w5jhsw	130	24	partial	partial	JJ
cord-260708-l9w5jhsw	130	25	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	130	26	-	-	HYPH
cord-260708-l9w5jhsw	130	27	targeting	target	VBG
cord-260708-l9w5jhsw	130	28	information	information	NN
cord-260708-l9w5jhsw	130	29	is	be	VBZ
cord-260708-l9w5jhsw	130	30	located	locate	VBN
cord-260708-l9w5jhsw	130	31	in	in	IN
cord-260708-l9w5jhsw	130	32	the	the	DT
cord-260708-l9w5jhsw	130	33	Gn	Gn	NNP
cord-260708-l9w5jhsw	130	34	ectodomain	ectodomain	NNP
cord-260708-l9w5jhsw	130	35	[	[	-LRB-
cord-260708-l9w5jhsw	130	36	17	17	CD
cord-260708-l9w5jhsw	130	37	]	]	-RRB-
cord-260708-l9w5jhsw	130	38	.	.	.
cord-260708-l9w5jhsw	131	1	The	the	DT
cord-260708-l9w5jhsw	131	2	final	final	JJ
cord-260708-l9w5jhsw	131	3	processing	processing	NN
cord-260708-l9w5jhsw	131	4	of	of	IN
cord-260708-l9w5jhsw	131	5	the	the	DT
cord-260708-l9w5jhsw	131	6	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	131	7	takes	take	VBZ
cord-260708-l9w5jhsw	131	8	place	place	NN
cord-260708-l9w5jhsw	131	9	in	in	IN
cord-260708-l9w5jhsw	131	10	the	the	DT
cord-260708-l9w5jhsw	131	11	trans	trans	NNP
cord-260708-l9w5jhsw	131	12	-	-	NNP
cord-260708-l9w5jhsw	131	13	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	131	14	,	,	,
cord-260708-l9w5jhsw	131	15	where	where	WRB
cord-260708-l9w5jhsw	131	16	the	the	DT
cord-260708-l9w5jhsw	131	17	mucin	mucin	NN
cord-260708-l9w5jhsw	131	18	-	-	HYPH
cord-260708-l9w5jhsw	131	19	like	like	JJ
cord-260708-l9w5jhsw	131	20	domain	domain	NN
cord-260708-l9w5jhsw	131	21	and	and	CC
cord-260708-l9w5jhsw	131	22	GP38	GP38	NNP
cord-260708-l9w5jhsw	131	23	are	be	VBP
cord-260708-l9w5jhsw	131	24	separated	separate	VBN
cord-260708-l9w5jhsw	131	25	from	from	IN
cord-260708-l9w5jhsw	131	26	each	each	DT
cord-260708-l9w5jhsw	131	27	other	other	JJ
cord-260708-l9w5jhsw	131	28	by	by	IN
cord-260708-l9w5jhsw	131	29	a	a	DT
cord-260708-l9w5jhsw	131	30	furin	furin	NN
cord-260708-l9w5jhsw	131	31	-	-	HYPH
cord-260708-l9w5jhsw	131	32	like	like	JJ
cord-260708-l9w5jhsw	131	33	protein	protein	NN
cord-260708-l9w5jhsw	131	34	convertase	convertase	NN
cord-260708-l9w5jhsw	131	35	at	at	IN
cord-260708-l9w5jhsw	131	36	the	the	DT
cord-260708-l9w5jhsw	131	37	RSKR	RSKR	NNP
cord-260708-l9w5jhsw	131	38	;	;	:
cord-260708-l9w5jhsw	131	39	cleavage	cleavage	NN
cord-260708-l9w5jhsw	131	40	site	site	NN
cord-260708-l9w5jhsw	131	41	[	[	-LRB-
cord-260708-l9w5jhsw	131	42	116	116	CD
cord-260708-l9w5jhsw	131	43	,	,	,
cord-260708-l9w5jhsw	131	44	145	145	CD
cord-260708-l9w5jhsw	131	45	]	]	-RRB-
cord-260708-l9w5jhsw	131	46	.	.	.
cord-260708-l9w5jhsw	132	1	This	this	DT
cord-260708-l9w5jhsw	132	2	cleavage	cleavage	NN
cord-260708-l9w5jhsw	132	3	is	be	VBZ
cord-260708-l9w5jhsw	132	4	not	not	RB
cord-260708-l9w5jhsw	132	5	required	require	VBN
cord-260708-l9w5jhsw	132	6	for	for	IN
cord-260708-l9w5jhsw	132	7	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	132	8	Gn	Gn	NNP
cord-260708-l9w5jhsw	132	9	maturation	maturation	NN
cord-260708-l9w5jhsw	132	10	[	[	-LRB-
cord-260708-l9w5jhsw	132	11	145	145	CD
cord-260708-l9w5jhsw	132	12	]	]	-RRB-
cord-260708-l9w5jhsw	132	13	,	,	,
cord-260708-l9w5jhsw	132	14	and	and	CC
cord-260708-l9w5jhsw	132	15	it	-PRON-	PRP
cord-260708-l9w5jhsw	132	16	appears	appear	VBZ
cord-260708-l9w5jhsw	132	17	that	that	IN
cord-260708-l9w5jhsw	132	18	not	not	RB
cord-260708-l9w5jhsw	132	19	the	the	DT
cord-260708-l9w5jhsw	132	20	entire	entire	JJ
cord-260708-l9w5jhsw	132	21	pool	pool	NN
cord-260708-l9w5jhsw	132	22	of	of	IN
cord-260708-l9w5jhsw	132	23	mucin	mucin	NN
cord-260708-l9w5jhsw	132	24	-	-	HYPH
cord-260708-l9w5jhsw	132	25	like	like	JJ
cord-260708-l9w5jhsw	132	26	domain/	domain/	ADD
cord-260708-l9w5jhsw	133	1	GP38	GP38	NNP
cord-260708-l9w5jhsw	133	2	polyprotein	polyprotein	NNP
cord-260708-l9w5jhsw	133	3	is	be	VBZ
cord-260708-l9w5jhsw	133	4	being	be	VBG
cord-260708-l9w5jhsw	133	5	cleaved	cleave	VBN
cord-260708-l9w5jhsw	133	6	,	,	,
cord-260708-l9w5jhsw	133	7	as	as	IN
cord-260708-l9w5jhsw	133	8	the	the	DT
cord-260708-l9w5jhsw	133	9	nonstructural	nonstructural	JJ
cord-260708-l9w5jhsw	133	10	proteins	protein	NNS
cord-260708-l9w5jhsw	133	11	termed	term	VBD
cord-260708-l9w5jhsw	133	12	GP85	GP85	NNP
cord-260708-l9w5jhsw	133	13	and	and	CC
cord-260708-l9w5jhsw	133	14	GP160	GP160	NNP
cord-260708-l9w5jhsw	133	15	contain	contain	VBP
cord-260708-l9w5jhsw	133	16	both	both	CC
cord-260708-l9w5jhsw	133	17	the	the	DT
cord-260708-l9w5jhsw	133	18	mucin	mucin	NN
cord-260708-l9w5jhsw	133	19	-	-	HYPH
cord-260708-l9w5jhsw	133	20	like	like	JJ
cord-260708-l9w5jhsw	133	21	domain	domain	NN
cord-260708-l9w5jhsw	133	22	and	and	CC
cord-260708-l9w5jhsw	133	23	GP38	GP38	NNP
cord-260708-l9w5jhsw	133	24	and	and	CC
cord-260708-l9w5jhsw	133	25	are	be	VBP
cord-260708-l9w5jhsw	133	26	resistant	resistant	JJ
cord-260708-l9w5jhsw	133	27	to	to	IN
cord-260708-l9w5jhsw	133	28	resolution	resolution	NN
cord-260708-l9w5jhsw	133	29	into	into	IN
cord-260708-l9w5jhsw	133	30	smaller	small	JJR
cord-260708-l9w5jhsw	133	31	proteins	protein	NNS
cord-260708-l9w5jhsw	133	32	by	by	IN
cord-260708-l9w5jhsw	133	33	denaturation	denaturation	NN
cord-260708-l9w5jhsw	133	34	in	in	IN
cord-260708-l9w5jhsw	133	35	SDS	SDS	NNP
cord-260708-l9w5jhsw	133	36	and	and	CC
cord-260708-l9w5jhsw	133	37	urea	urea	NN
cord-260708-l9w5jhsw	133	38	[	[	-LRB-
cord-260708-l9w5jhsw	133	39	145	145	CD
cord-260708-l9w5jhsw	133	40	]	]	-RRB-
cord-260708-l9w5jhsw	133	41	.	.	.
cord-260708-l9w5jhsw	134	1	Resistance	resistance	NN
cord-260708-l9w5jhsw	134	2	to	to	IN
cord-260708-l9w5jhsw	134	3	denaturation	denaturation	NN
cord-260708-l9w5jhsw	134	4	also	also	RB
cord-260708-l9w5jhsw	134	5	suggests	suggest	VBZ
cord-260708-l9w5jhsw	134	6	that	that	IN
cord-260708-l9w5jhsw	134	7	GP160	GP160	NNP
cord-260708-l9w5jhsw	134	8	is	be	VBZ
cord-260708-l9w5jhsw	134	9	probably	probably	RB
cord-260708-l9w5jhsw	134	10	not	not	RB
cord-260708-l9w5jhsw	134	11	a	a	DT
cord-260708-l9w5jhsw	134	12	dimer	dimer	NN
cord-260708-l9w5jhsw	134	13	of	of	IN
cord-260708-l9w5jhsw	134	14	GP85	GP85	NNP
cord-260708-l9w5jhsw	134	15	[	[	-LRB-
cord-260708-l9w5jhsw	134	16	145	145	CD
cord-260708-l9w5jhsw	134	17	]	]	-RRB-
cord-260708-l9w5jhsw	134	18	.	.	.
cord-260708-l9w5jhsw	135	1	Interestingly	interestingly	RB
cord-260708-l9w5jhsw	135	2	,	,	,
cord-260708-l9w5jhsw	135	3	the	the	DT
cord-260708-l9w5jhsw	135	4	mucin	mucin	NN
cord-260708-l9w5jhsw	135	5	-	-	HYPH
cord-260708-l9w5jhsw	135	6	like	like	JJ
cord-260708-l9w5jhsw	135	7	domain	domain	NN
cord-260708-l9w5jhsw	135	8	/	/	SYM
cord-260708-l9w5jhsw	135	9	GP38	GP38	NNP
cord-260708-l9w5jhsw	135	10	and	and	CC
cord-260708-l9w5jhsw	135	11	GP38	GP38	NNP
cord-260708-l9w5jhsw	135	12	can	can	MD
cord-260708-l9w5jhsw	135	13	fold	fold	VB
cord-260708-l9w5jhsw	135	14	independently	independently	RB
cord-260708-l9w5jhsw	135	15	of	of	IN
cord-260708-l9w5jhsw	135	16	the	the	DT
cord-260708-l9w5jhsw	135	17	rest	rest	NN
cord-260708-l9w5jhsw	135	18	of	of	IN
cord-260708-l9w5jhsw	135	19	Gn	Gn	NNP
cord-260708-l9w5jhsw	135	20	and	and	CC
cord-260708-l9w5jhsw	135	21	are	be	VBP
cord-260708-l9w5jhsw	135	22	secreted	secrete	VBN
cord-260708-l9w5jhsw	135	23	even	even	RB
cord-260708-l9w5jhsw	135	24	when	when	WRB
cord-260708-l9w5jhsw	135	25	expressed	express	VBN
cord-260708-l9w5jhsw	135	26	on	on	IN
cord-260708-l9w5jhsw	135	27	their	-PRON-	PRP$
cord-260708-l9w5jhsw	135	28	own	own	JJ
cord-260708-l9w5jhsw	135	29	in	in	IN
cord-260708-l9w5jhsw	135	30	transfected	transfecte	VBN
cord-260708-l9w5jhsw	135	31	cells	cell	NNS
cord-260708-l9w5jhsw	135	32	[	[	-LRB-
cord-260708-l9w5jhsw	135	33	145	145	CD
cord-260708-l9w5jhsw	135	34	]	]	-RRB-
cord-260708-l9w5jhsw	135	35	.	.	.
cord-260708-l9w5jhsw	136	1	No	no	DT
cord-260708-l9w5jhsw	136	2	specific	specific	JJ
cord-260708-l9w5jhsw	136	3	biological	biological	JJ
cord-260708-l9w5jhsw	136	4	function	function	NN
cord-260708-l9w5jhsw	136	5	has	have	VBZ
cord-260708-l9w5jhsw	136	6	been	be	VBN
cord-260708-l9w5jhsw	136	7	assigned	assign	VBN
cord-260708-l9w5jhsw	136	8	to	to	IN
cord-260708-l9w5jhsw	136	9	the	the	DT
cord-260708-l9w5jhsw	136	10	mucinlike	mucinlike	JJ
cord-260708-l9w5jhsw	136	11	domain	domain	NN
cord-260708-l9w5jhsw	136	12	,	,	,
cord-260708-l9w5jhsw	136	13	GP38	GP38	NNP
cord-260708-l9w5jhsw	136	14	,	,	,
cord-260708-l9w5jhsw	136	15	GP85	GP85	NNP
cord-260708-l9w5jhsw	136	16	or	or	CC
cord-260708-l9w5jhsw	136	17	GP160	GP160	NNP
cord-260708-l9w5jhsw	136	18	.	.	.
cord-260708-l9w5jhsw	137	1	The	the	DT
cord-260708-l9w5jhsw	137	2	mucin	mucin	NN
cord-260708-l9w5jhsw	137	3	-	-	HYPH
cord-260708-l9w5jhsw	137	4	like	like	JJ
cord-260708-l9w5jhsw	137	5	domain	domain	NN
cord-260708-l9w5jhsw	137	6	of	of	IN
cord-260708-l9w5jhsw	137	7	the	the	DT
cord-260708-l9w5jhsw	137	8	Ebola	Ebola	NNP
cord-260708-l9w5jhsw	137	9	virus	virus	NN
cord-260708-l9w5jhsw	137	10	glycoprotein	glycoprotein	NN
cord-260708-l9w5jhsw	137	11	has	have	VBZ
cord-260708-l9w5jhsw	137	12	been	be	VBN
cord-260708-l9w5jhsw	137	13	shown	show	VBN
cord-260708-l9w5jhsw	137	14	to	to	TO
cord-260708-l9w5jhsw	137	15	play	play	VB
cord-260708-l9w5jhsw	137	16	a	a	DT
cord-260708-l9w5jhsw	137	17	major	major	JJ
cord-260708-l9w5jhsw	137	18	role	role	NN
cord-260708-l9w5jhsw	137	19	in	in	IN
cord-260708-l9w5jhsw	137	20	pathogenesis	pathogenesis	NN
cord-260708-l9w5jhsw	137	21	,	,	,
cord-260708-l9w5jhsw	137	22	including	include	VBG
cord-260708-l9w5jhsw	137	23	involvement	involvement	NN
cord-260708-l9w5jhsw	137	24	in	in	IN
cord-260708-l9w5jhsw	137	25	the	the	DT
cord-260708-l9w5jhsw	137	26	observed	observed	JJ
cord-260708-l9w5jhsw	137	27	increase	increase	NN
cord-260708-l9w5jhsw	137	28	of	of	IN
cord-260708-l9w5jhsw	137	29	endothelium	endothelium	NN
cord-260708-l9w5jhsw	137	30	permeability	permeability	NN
cord-260708-l9w5jhsw	137	31	[	[	-LRB-
cord-260708-l9w5jhsw	137	32	154	154	CD
cord-260708-l9w5jhsw	137	33	,	,	,
cord-260708-l9w5jhsw	137	34	188	188	CD
cord-260708-l9w5jhsw	137	35	]	]	-RRB-
cord-260708-l9w5jhsw	137	36	,	,	,
cord-260708-l9w5jhsw	137	37	and	and	CC
cord-260708-l9w5jhsw	137	38	it	-PRON-	PRP
cord-260708-l9w5jhsw	137	39	will	will	MD
cord-260708-l9w5jhsw	137	40	be	be	VB
cord-260708-l9w5jhsw	137	41	important	important	JJ
cord-260708-l9w5jhsw	137	42	to	to	TO
cord-260708-l9w5jhsw	137	43	see	see	VB
cord-260708-l9w5jhsw	137	44	if	if	IN
cord-260708-l9w5jhsw	137	45	this	this	DT
cord-260708-l9w5jhsw	137	46	is	be	VBZ
cord-260708-l9w5jhsw	137	47	also	also	RB
cord-260708-l9w5jhsw	137	48	true	true	JJ
cord-260708-l9w5jhsw	137	49	of	of	IN
cord-260708-l9w5jhsw	137	50	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	137	51	,	,	,
cord-260708-l9w5jhsw	137	52	especially	especially	RB
cord-260708-l9w5jhsw	137	53	given	give	VBN
cord-260708-l9w5jhsw	137	54	the	the	DT
cord-260708-l9w5jhsw	137	55	changes	change	NNS
cord-260708-l9w5jhsw	137	56	visible	visible	JJ
cord-260708-l9w5jhsw	137	57	in	in	IN
cord-260708-l9w5jhsw	137	58	the	the	DT
cord-260708-l9w5jhsw	137	59	endothelial	endothelial	JJ
cord-260708-l9w5jhsw	137	60	cells	cell	NNS
cord-260708-l9w5jhsw	137	61	of	of	IN
cord-260708-l9w5jhsw	137	62	CCHFV	cchfv	NN
cord-260708-l9w5jhsw	137	63	patients	patient	NNS
cord-260708-l9w5jhsw	137	64	.	.	.
cord-260708-l9w5jhsw	138	1	The	the	DT
cord-260708-l9w5jhsw	138	2	NS	NS	NNP
cord-260708-l9w5jhsw	138	3	M	M	NNP
cord-260708-l9w5jhsw	138	4	protein	protein	NN
cord-260708-l9w5jhsw	138	5	,	,	,
cord-260708-l9w5jhsw	138	6	when	when	WRB
cord-260708-l9w5jhsw	138	7	expressed	express	VBN
cord-260708-l9w5jhsw	138	8	in	in	IN
cord-260708-l9w5jhsw	138	9	transfected	transfected	JJ
cord-260708-l9w5jhsw	138	10	cells	cell	NNS
cord-260708-l9w5jhsw	138	11	on	on	IN
cord-260708-l9w5jhsw	138	12	its	-PRON-	PRP$
cord-260708-l9w5jhsw	138	13	own	own	JJ
cord-260708-l9w5jhsw	138	14	,	,	,
cord-260708-l9w5jhsw	138	15	is	be	VBZ
cord-260708-l9w5jhsw	138	16	transported	transport	VBN
cord-260708-l9w5jhsw	138	17	to	to	IN
cord-260708-l9w5jhsw	138	18	the	the	DT
cord-260708-l9w5jhsw	138	19	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	138	20	[	[	-LRB-
cord-260708-l9w5jhsw	138	21	3	3	CD
cord-260708-l9w5jhsw	138	22	]	]	-RRB-
cord-260708-l9w5jhsw	138	23	.	.	.
cord-260708-l9w5jhsw	139	1	While	while	IN
cord-260708-l9w5jhsw	139	2	the	the	DT
cord-260708-l9w5jhsw	139	3	function(s	function(s	NNP
cord-260708-l9w5jhsw	139	4	)	)	-RRB-
cord-260708-l9w5jhsw	139	5	of	of	IN
cord-260708-l9w5jhsw	139	6	the	the	DT
cord-260708-l9w5jhsw	139	7	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	139	8	NS	NS	NNP
cord-260708-l9w5jhsw	139	9	M	M	NNP
cord-260708-l9w5jhsw	139	10	have	have	VBP
cord-260708-l9w5jhsw	139	11	still	still	RB
cord-260708-l9w5jhsw	139	12	to	to	TO
cord-260708-l9w5jhsw	139	13	be	be	VB
cord-260708-l9w5jhsw	139	14	determined	determine	VBN
cord-260708-l9w5jhsw	139	15	,	,	,
cord-260708-l9w5jhsw	139	16	the	the	DT
cord-260708-l9w5jhsw	139	17	fact	fact	NN
cord-260708-l9w5jhsw	139	18	that	that	IN
cord-260708-l9w5jhsw	139	19	Gn	Gn	NNP
cord-260708-l9w5jhsw	139	20	requires	require	VBZ
cord-260708-l9w5jhsw	139	21	NS	NS	NNP
cord-260708-l9w5jhsw	139	22	M	M	NNP
cord-260708-l9w5jhsw	139	23	for	for	IN
cord-260708-l9w5jhsw	139	24	maturation	maturation	NN
cord-260708-l9w5jhsw	139	25	may	may	MD
cord-260708-l9w5jhsw	139	26	mean	mean	VB
cord-260708-l9w5jhsw	139	27	that	that	IN
cord-260708-l9w5jhsw	139	28	NS	NS	NNP
cord-260708-l9w5jhsw	139	29	M	M	NNP
cord-260708-l9w5jhsw	139	30	is	be	VBZ
cord-260708-l9w5jhsw	139	31	necessary	necessary	JJ
cord-260708-l9w5jhsw	139	32	for	for	IN
cord-260708-l9w5jhsw	139	33	virus	virus	NN
cord-260708-l9w5jhsw	139	34	replication	replication	NN
cord-260708-l9w5jhsw	139	35	[	[	-LRB-
cord-260708-l9w5jhsw	139	36	3	3	CD
cord-260708-l9w5jhsw	139	37	]	]	-RRB-
cord-260708-l9w5jhsw	139	38	.	.	.
cord-260708-l9w5jhsw	140	1	Glycosylation	glycosylation	NN
cord-260708-l9w5jhsw	140	2	is	be	VBZ
cord-260708-l9w5jhsw	140	3	an	an	DT
cord-260708-l9w5jhsw	140	4	important	important	JJ
cord-260708-l9w5jhsw	140	5	post	post	JJ
cord-260708-l9w5jhsw	140	6	-	-	JJ
cord-260708-l9w5jhsw	140	7	translational	translational	JJ
cord-260708-l9w5jhsw	140	8	modification	modification	NN
cord-260708-l9w5jhsw	140	9	of	of	IN
cord-260708-l9w5jhsw	140	10	secreted	secrete	VBN
cord-260708-l9w5jhsw	140	11	and	and	CC
cord-260708-l9w5jhsw	140	12	membrane	membrane	NN
cord-260708-l9w5jhsw	140	13	proteins	protein	NNS
cord-260708-l9w5jhsw	140	14	that	that	WDT
cord-260708-l9w5jhsw	140	15	can	can	MD
cord-260708-l9w5jhsw	140	16	influence	influence	VB
cord-260708-l9w5jhsw	140	17	protein	protein	NN
cord-260708-l9w5jhsw	140	18	folding	folding	NN
cord-260708-l9w5jhsw	140	19	,	,	,
cord-260708-l9w5jhsw	140	20	transport	transport	NN
cord-260708-l9w5jhsw	140	21	and	and	CC
cord-260708-l9w5jhsw	140	22	function	function	NN
cord-260708-l9w5jhsw	140	23	.	.	.
cord-260708-l9w5jhsw	141	1	N	n	CD
cord-260708-l9w5jhsw	141	2	-	-	HYPH
cord-260708-l9w5jhsw	141	3	linked	link	VBN
cord-260708-l9w5jhsw	141	4	glycosylation	glycosylation	NN
cord-260708-l9w5jhsw	141	5	in	in	IN
cord-260708-l9w5jhsw	141	6	particular	particular	JJ
cord-260708-l9w5jhsw	141	7	is	be	VBZ
cord-260708-l9w5jhsw	141	8	known	know	VBN
cord-260708-l9w5jhsw	141	9	to	to	TO
cord-260708-l9w5jhsw	141	10	regulate	regulate	VB
cord-260708-l9w5jhsw	141	11	protein	protein	NN
cord-260708-l9w5jhsw	141	12	folding	folding	NN
cord-260708-l9w5jhsw	141	13	,	,	,
cord-260708-l9w5jhsw	141	14	association	association	NN
cord-260708-l9w5jhsw	141	15	with	with	IN
cord-260708-l9w5jhsw	141	16	chaperones	chaperone	NNS
cord-260708-l9w5jhsw	141	17	[	[	-LRB-
cord-260708-l9w5jhsw	141	18	112	112	CD
cord-260708-l9w5jhsw	141	19	]	]	-RRB-
cord-260708-l9w5jhsw	141	20	,	,	,
cord-260708-l9w5jhsw	141	21	transport	transport	NN
cord-260708-l9w5jhsw	141	22	,	,	,
cord-260708-l9w5jhsw	141	23	cellular	cellular	JJ
cord-260708-l9w5jhsw	141	24	localisation	localisation	NN
cord-260708-l9w5jhsw	141	25	[	[	-LRB-
cord-260708-l9w5jhsw	141	26	81	81	CD
cord-260708-l9w5jhsw	141	27	,	,	,
cord-260708-l9w5jhsw	141	28	82	82	CD
cord-260708-l9w5jhsw	141	29	]	]	-RRB-
cord-260708-l9w5jhsw	141	30	,	,	,
cord-260708-l9w5jhsw	141	31	and	and	CC
cord-260708-l9w5jhsw	141	32	even	even	RB
cord-260708-l9w5jhsw	141	33	virus	virus	NN
cord-260708-l9w5jhsw	141	34	infectivity	infectivity	NN
cord-260708-l9w5jhsw	141	35	(	(	-LRB-
cord-260708-l9w5jhsw	141	36	reviewed	review	VBN
cord-260708-l9w5jhsw	141	37	in	in	IN
cord-260708-l9w5jhsw	141	38	ref	ref	NN
cord-260708-l9w5jhsw	141	39	.	.	.
cord-260708-l9w5jhsw	142	1	[	[	-LRB-
cord-260708-l9w5jhsw	142	2	171	171	CD
cord-260708-l9w5jhsw	142	3	]	]	-RRB-
cord-260708-l9w5jhsw	142	4	)	)	-RRB-
cord-260708-l9w5jhsw	142	5	.	.	.
cord-260708-l9w5jhsw	143	1	The	the	DT
cord-260708-l9w5jhsw	143	2	N	n	CD
cord-260708-l9w5jhsw	143	3	-	-	HYPH
cord-260708-l9w5jhsw	143	4	terminal	terminal	JJ
cord-260708-l9w5jhsw	143	5	part	part	NN
cord-260708-l9w5jhsw	143	6	of	of	IN
cord-260708-l9w5jhsw	143	7	the	the	DT
cord-260708-l9w5jhsw	143	8	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	143	9	M	M	NNP
cord-260708-l9w5jhsw	143	10	polyprotein	polyprotein	NNP
cord-260708-l9w5jhsw	143	11	,	,	,
cord-260708-l9w5jhsw	143	12	which	which	WDT
cord-260708-l9w5jhsw	143	13	contains	contain	VBZ
cord-260708-l9w5jhsw	143	14	the	the	DT
cord-260708-l9w5jhsw	143	15	mucin	mucin	NN
cord-260708-l9w5jhsw	143	16	-	-	HYPH
cord-260708-l9w5jhsw	143	17	like	like	JJ
cord-260708-l9w5jhsw	143	18	domain	domain	NN
cord-260708-l9w5jhsw	143	19	,	,	,
cord-260708-l9w5jhsw	143	20	is	be	VBZ
cord-260708-l9w5jhsw	143	21	heavily	heavily	RB
cord-260708-l9w5jhsw	143	22	O	o	NN
cord-260708-l9w5jhsw	143	23	-	-	HYPH
cord-260708-l9w5jhsw	143	24	glycosylated	glycosylated	JJ
cord-260708-l9w5jhsw	143	25	,	,	,
cord-260708-l9w5jhsw	143	26	while	while	IN
cord-260708-l9w5jhsw	143	27	the	the	DT
cord-260708-l9w5jhsw	143	28	adjacent	adjacent	JJ
cord-260708-l9w5jhsw	143	29	GP38	GP38	NNP
cord-260708-l9w5jhsw	143	30	domain	domain	NN
cord-260708-l9w5jhsw	143	31	appears	appear	VBZ
cord-260708-l9w5jhsw	143	32	to	to	TO
cord-260708-l9w5jhsw	143	33	have	have	VB
cord-260708-l9w5jhsw	143	34	few	few	JJ
cord-260708-l9w5jhsw	143	35	O	o	NN
cord-260708-l9w5jhsw	143	36	-	-	HYPH
cord-260708-l9w5jhsw	143	37	glycosylation	glycosylation	NN
cord-260708-l9w5jhsw	143	38	sites	site	NNS
cord-260708-l9w5jhsw	143	39	[	[	-LRB-
cord-260708-l9w5jhsw	143	40	144	144	CD
cord-260708-l9w5jhsw	143	41	,	,	,
cord-260708-l9w5jhsw	143	42	145	145	CD
cord-260708-l9w5jhsw	143	43	]	]	-RRB-
cord-260708-l9w5jhsw	143	44	.	.	.
cord-260708-l9w5jhsw	144	1	Both	both	DT
cord-260708-l9w5jhsw	144	2	domains	domain	NNS
cord-260708-l9w5jhsw	144	3	are	be	VBP
cord-260708-l9w5jhsw	144	4	also	also	RB
cord-260708-l9w5jhsw	144	5	N	n	CD
cord-260708-l9w5jhsw	144	6	-	-	HYPH
cord-260708-l9w5jhsw	144	7	glycosylated	glycosylate	VBN
cord-260708-l9w5jhsw	144	8	,	,	,
cord-260708-l9w5jhsw	144	9	the	the	DT
cord-260708-l9w5jhsw	144	10	mucin	mucin	NN
cord-260708-l9w5jhsw	144	11	-	-	HYPH
cord-260708-l9w5jhsw	144	12	like	like	JJ
cord-260708-l9w5jhsw	144	13	domain	domain	NN
cord-260708-l9w5jhsw	144	14	containing	contain	VBG
cord-260708-l9w5jhsw	144	15	five	five	CD
cord-260708-l9w5jhsw	144	16	potential	potential	JJ
cord-260708-l9w5jhsw	144	17	sites	site	NNS
cord-260708-l9w5jhsw	144	18	and	and	CC
cord-260708-l9w5jhsw	144	19	GP38	GP38	NNP
cord-260708-l9w5jhsw	144	20	two	two	CD
cord-260708-l9w5jhsw	144	21	[	[	-LRB-
cord-260708-l9w5jhsw	144	22	145	145	CD
cord-260708-l9w5jhsw	144	23	]	]	-RRB-
cord-260708-l9w5jhsw	144	24	.	.	.
cord-260708-l9w5jhsw	145	1	Of	of	IN
cord-260708-l9w5jhsw	145	2	two	two	CD
cord-260708-l9w5jhsw	145	3	predicted	predict	VBN
cord-260708-l9w5jhsw	145	4	N	n	NN
cord-260708-l9w5jhsw	145	5	-	-	HYPH
cord-260708-l9w5jhsw	145	6	glycosylation	glycosylation	NN
cord-260708-l9w5jhsw	145	7	sites	site	NNS
cord-260708-l9w5jhsw	145	8	in	in	IN
cord-260708-l9w5jhsw	145	9	each	each	DT
cord-260708-l9w5jhsw	145	10	of	of	IN
cord-260708-l9w5jhsw	145	11	the	the	DT
cord-260708-l9w5jhsw	145	12	mature	mature	JJ
cord-260708-l9w5jhsw	145	13	Gn	Gn	NNP
cord-260708-l9w5jhsw	145	14	and	and	CC
cord-260708-l9w5jhsw	145	15	Gc	Gc	NNP
cord-260708-l9w5jhsw	145	16	proteins	protein	NNS
cord-260708-l9w5jhsw	145	17	,	,	,
cord-260708-l9w5jhsw	145	18	only	only	RB
cord-260708-l9w5jhsw	145	19	one	one	CD
cord-260708-l9w5jhsw	145	20	is	be	VBZ
cord-260708-l9w5jhsw	145	21	functional	functional	JJ
cord-260708-l9w5jhsw	145	22	in	in	IN
cord-260708-l9w5jhsw	145	23	Gn	Gn	NNP
cord-260708-l9w5jhsw	145	24	(	(	-LRB-
cord-260708-l9w5jhsw	145	25	N557	n557	NN
cord-260708-l9w5jhsw	145	26	)	)	-RRB-
cord-260708-l9w5jhsw	145	27	,	,	,
cord-260708-l9w5jhsw	145	28	while	while	IN
cord-260708-l9w5jhsw	145	29	both	both	DT
cord-260708-l9w5jhsw	145	30	sites	site	NNS
cord-260708-l9w5jhsw	145	31	in	in	IN
cord-260708-l9w5jhsw	145	32	Gc	Gc	NNP
cord-260708-l9w5jhsw	145	33	(	(	-LRB-
cord-260708-l9w5jhsw	145	34	N1054	N1054	NNP
cord-260708-l9w5jhsw	145	35	and	and	CC
cord-260708-l9w5jhsw	145	36	N1563	N1563	NNP
cord-260708-l9w5jhsw	145	37	)	)	-RRB-
cord-260708-l9w5jhsw	145	38	are	be	VBP
cord-260708-l9w5jhsw	145	39	glycosylated	glycosylate	VBN
cord-260708-l9w5jhsw	145	40	[	[	-LRB-
cord-260708-l9w5jhsw	145	41	59	59	CD
cord-260708-l9w5jhsw	145	42	]	]	-RRB-
cord-260708-l9w5jhsw	145	43	.	.	.
cord-260708-l9w5jhsw	146	1	However	however	RB
cord-260708-l9w5jhsw	146	2	,	,	,
cord-260708-l9w5jhsw	146	3	only	only	RB
cord-260708-l9w5jhsw	146	4	the	the	DT
cord-260708-l9w5jhsw	146	5	glycosylation	glycosylation	NN
cord-260708-l9w5jhsw	146	6	of	of	IN
cord-260708-l9w5jhsw	146	7	the	the	DT
cord-260708-l9w5jhsw	146	8	Gn	Gn	NNP
cord-260708-l9w5jhsw	146	9	is	be	VBZ
cord-260708-l9w5jhsw	146	10	essential	essential	JJ
cord-260708-l9w5jhsw	146	11	for	for	IN
cord-260708-l9w5jhsw	146	12	Gn	Gn	NNP
cord-260708-l9w5jhsw	146	13	maturation	maturation	NN
cord-260708-l9w5jhsw	146	14	,	,	,
cord-260708-l9w5jhsw	146	15	correct	correct	JJ
cord-260708-l9w5jhsw	146	16	localisation	localisation	NN
cord-260708-l9w5jhsw	146	17	,	,	,
cord-260708-l9w5jhsw	146	18	and	and	CC
cord-260708-l9w5jhsw	146	19	transport	transport	NN
cord-260708-l9w5jhsw	146	20	of	of	IN
cord-260708-l9w5jhsw	146	21	itself	-PRON-	PRP
cord-260708-l9w5jhsw	146	22	and	and	CC
cord-260708-l9w5jhsw	146	23	other	other	JJ
cord-260708-l9w5jhsw	146	24	CCHFV	cchfv	NN
cord-260708-l9w5jhsw	146	25	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	146	26	[	[	-LRB-
cord-260708-l9w5jhsw	146	27	59	59	CD
cord-260708-l9w5jhsw	146	28	]	]	-RRB-
cord-260708-l9w5jhsw	146	29	.	.	.
cord-260708-l9w5jhsw	147	1	Given	give	VBN
cord-260708-l9w5jhsw	147	2	that	that	IN
cord-260708-l9w5jhsw	147	3	the	the	DT
cord-260708-l9w5jhsw	147	4	Gn	Gn	NNP
cord-260708-l9w5jhsw	147	5	glycosylation	glycosylation	NN
cord-260708-l9w5jhsw	147	6	sites	site	NNS
cord-260708-l9w5jhsw	147	7	are	be	VBP
cord-260708-l9w5jhsw	147	8	conserved	conserve	VBN
cord-260708-l9w5jhsw	147	9	among	among	IN
cord-260708-l9w5jhsw	147	10	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	147	11	strains	strain	NNS
cord-260708-l9w5jhsw	147	12	[	[	-LRB-
cord-260708-l9w5jhsw	147	13	51	51	CD
cord-260708-l9w5jhsw	147	14	]	]	-RRB-
cord-260708-l9w5jhsw	147	15	,	,	,
cord-260708-l9w5jhsw	147	16	it	-PRON-	PRP
cord-260708-l9w5jhsw	147	17	is	be	VBZ
cord-260708-l9w5jhsw	147	18	likely	likely	JJ
cord-260708-l9w5jhsw	147	19	that	that	DT
cord-260708-l9w5jhsw	147	20	correct	correct	JJ
cord-260708-l9w5jhsw	147	21	glycosylation	glycosylation	NN
cord-260708-l9w5jhsw	147	22	of	of	IN
cord-260708-l9w5jhsw	147	23	the	the	DT
cord-260708-l9w5jhsw	147	24	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	148	1	Gn	Gn	NNP
cord-260708-l9w5jhsw	148	2	is	be	VBZ
cord-260708-l9w5jhsw	148	3	critical	critical	JJ
cord-260708-l9w5jhsw	148	4	for	for	IN
cord-260708-l9w5jhsw	148	5	virus	virus	NN
cord-260708-l9w5jhsw	148	6	viability	viability	NN
cord-260708-l9w5jhsw	148	7	.	.	.
cord-260708-l9w5jhsw	149	1	Recently	recently	RB
cord-260708-l9w5jhsw	149	2	,	,	,
cord-260708-l9w5jhsw	149	3	NMR	NMR	NNP
cord-260708-l9w5jhsw	149	4	has	have	VBZ
cord-260708-l9w5jhsw	149	5	been	be	VBN
cord-260708-l9w5jhsw	149	6	used	use	VBN
cord-260708-l9w5jhsw	149	7	to	to	TO
cord-260708-l9w5jhsw	149	8	determine	determine	VB
cord-260708-l9w5jhsw	149	9	a	a	DT
cord-260708-l9w5jhsw	149	10	solution	solution	NN
cord-260708-l9w5jhsw	149	11	structure	structure	NN
cord-260708-l9w5jhsw	149	12	for	for	IN
cord-260708-l9w5jhsw	149	13	the	the	DT
cord-260708-l9w5jhsw	149	14	C	C	NNP
cord-260708-l9w5jhsw	149	15	-	-	HYPH
cord-260708-l9w5jhsw	149	16	terminal	terminal	NN
cord-260708-l9w5jhsw	149	17	(	(	-LRB-
cord-260708-l9w5jhsw	149	18	cytoplasmic	cytoplasmic	JJ
cord-260708-l9w5jhsw	149	19	)	)	-RRB-
cord-260708-l9w5jhsw	149	20	tail	tail	NN
cord-260708-l9w5jhsw	149	21	of	of	IN
cord-260708-l9w5jhsw	149	22	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	149	23	Gn	Gn	NNP
cord-260708-l9w5jhsw	149	24	,	,	,
cord-260708-l9w5jhsw	149	25	showing	show	VBG
cord-260708-l9w5jhsw	149	26	that	that	IN
cord-260708-l9w5jhsw	149	27	this	this	DT
cord-260708-l9w5jhsw	149	28	region	region	NN
cord-260708-l9w5jhsw	149	29	contains	contain	VBZ
cord-260708-l9w5jhsw	149	30	a	a	DT
cord-260708-l9w5jhsw	149	31	dual	dual	JJ
cord-260708-l9w5jhsw	149	32	zinc	zinc	NN
cord-260708-l9w5jhsw	149	33	-	-	HYPH
cord-260708-l9w5jhsw	149	34	finger	finger	NN
cord-260708-l9w5jhsw	149	35	domain	domain	NN
cord-260708-l9w5jhsw	149	36	,	,	,
cord-260708-l9w5jhsw	149	37	the	the	DT
cord-260708-l9w5jhsw	149	38	sequence	sequence	NN
cord-260708-l9w5jhsw	149	39	of	of	IN
cord-260708-l9w5jhsw	149	40	which	which	WDT
cord-260708-l9w5jhsw	149	41	is	be	VBZ
cord-260708-l9w5jhsw	149	42	highly	highly	RB
cord-260708-l9w5jhsw	149	43	conserved	conserve	VBN
cord-260708-l9w5jhsw	149	44	among	among	IN
cord-260708-l9w5jhsw	149	45	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	149	46	[	[	-LRB-
cord-260708-l9w5jhsw	149	47	60	60	CD
cord-260708-l9w5jhsw	149	48	,	,	,
cord-260708-l9w5jhsw	149	49	61	61	CD
cord-260708-l9w5jhsw	149	50	]	]	-RRB-
cord-260708-l9w5jhsw	149	51	.	.	.
cord-260708-l9w5jhsw	150	1	Classical	classical	JJ
cord-260708-l9w5jhsw	150	2	bba	bba	NNP
cord-260708-l9w5jhsw	150	3	-	-	HYPH
cord-260708-l9w5jhsw	150	4	zinc	zinc	NN
cord-260708-l9w5jhsw	150	5	finger	finger	NN
cord-260708-l9w5jhsw	150	6	domains	domain	NNS
cord-260708-l9w5jhsw	150	7	have	have	VBP
cord-260708-l9w5jhsw	150	8	been	be	VBN
cord-260708-l9w5jhsw	150	9	shown	show	VBN
cord-260708-l9w5jhsw	150	10	to	to	TO
cord-260708-l9w5jhsw	150	11	take	take	VB
cord-260708-l9w5jhsw	150	12	part	part	NN
cord-260708-l9w5jhsw	150	13	in	in	IN
cord-260708-l9w5jhsw	150	14	protein	protein	NN
cord-260708-l9w5jhsw	150	15	-	-	HYPH
cord-260708-l9w5jhsw	150	16	protein	protein	NN
cord-260708-l9w5jhsw	150	17	interactions	interaction	NNS
cord-260708-l9w5jhsw	150	18	(	(	-LRB-
cord-260708-l9w5jhsw	150	19	reviewed	review	VBN
cord-260708-l9w5jhsw	150	20	in	in	IN
cord-260708-l9w5jhsw	150	21	ref	ref	NN
cord-260708-l9w5jhsw	150	22	.	.	.
cord-260708-l9w5jhsw	151	1	[	[	-LRB-
cord-260708-l9w5jhsw	151	2	71	71	CD
cord-260708-l9w5jhsw	151	3	]	]	-RRB-
cord-260708-l9w5jhsw	151	4	)	)	-RRB-
cord-260708-l9w5jhsw	151	5	,	,	.
cord-260708-l9w5jhsw	152	1	and	and	CC
cord-260708-l9w5jhsw	152	2	it	-PRON-	PRP
cord-260708-l9w5jhsw	152	3	is	be	VBZ
cord-260708-l9w5jhsw	152	4	possible	possible	JJ
cord-260708-l9w5jhsw	152	5	that	that	IN
cord-260708-l9w5jhsw	152	6	the	the	DT
cord-260708-l9w5jhsw	152	7	dual	dual	JJ
cord-260708-l9w5jhsw	152	8	zincfinger	zincfinger	NNP
cord-260708-l9w5jhsw	152	9	domain	domain	NN
cord-260708-l9w5jhsw	152	10	in	in	IN
cord-260708-l9w5jhsw	152	11	the	the	DT
cord-260708-l9w5jhsw	152	12	C	c	NN
cord-260708-l9w5jhsw	152	13	-	-	HYPH
cord-260708-l9w5jhsw	152	14	terminus	terminus	NN
cord-260708-l9w5jhsw	152	15	of	of	IN
cord-260708-l9w5jhsw	152	16	the	the	DT
cord-260708-l9w5jhsw	152	17	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	153	1	Gn	Gn	NNP
cord-260708-l9w5jhsw	153	2	protein	protein	NN
cord-260708-l9w5jhsw	153	3	is	be	VBZ
cord-260708-l9w5jhsw	153	4	involved	involve	VBN
cord-260708-l9w5jhsw	153	5	in	in	IN
cord-260708-l9w5jhsw	153	6	interaction	interaction	NN
cord-260708-l9w5jhsw	153	7	with	with	IN
cord-260708-l9w5jhsw	153	8	RNPs	rnp	NNS
cord-260708-l9w5jhsw	153	9	,	,	,
cord-260708-l9w5jhsw	153	10	which	which	WDT
cord-260708-l9w5jhsw	153	11	would	would	MD
cord-260708-l9w5jhsw	153	12	help	help	VB
cord-260708-l9w5jhsw	153	13	drive	drive	VB
cord-260708-l9w5jhsw	153	14	assembly	assembly	NN
cord-260708-l9w5jhsw	153	15	/	/	SYM
cord-260708-l9w5jhsw	153	16	budding	budding	NN
cord-260708-l9w5jhsw	153	17	of	of	IN
cord-260708-l9w5jhsw	153	18	the	the	DT
cord-260708-l9w5jhsw	153	19	virus	virus	NN
cord-260708-l9w5jhsw	153	20	.	.	.
cord-260708-l9w5jhsw	154	1	Analysis	analysis	NN
cord-260708-l9w5jhsw	154	2	of	of	IN
cord-260708-l9w5jhsw	154	3	the	the	DT
cord-260708-l9w5jhsw	154	4	sequences	sequence	NNS
cord-260708-l9w5jhsw	154	5	of	of	IN
cord-260708-l9w5jhsw	154	6	M	M	NNP
cord-260708-l9w5jhsw	154	7	segments	segment	NNS
cord-260708-l9w5jhsw	154	8	of	of	IN
cord-260708-l9w5jhsw	154	9	other	other	JJ
cord-260708-l9w5jhsw	154	10	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	154	11	suggests	suggest	VBZ
cord-260708-l9w5jhsw	154	12	that	that	IN
cord-260708-l9w5jhsw	154	13	the	the	DT
cord-260708-l9w5jhsw	154	14	general	general	JJ
cord-260708-l9w5jhsw	154	15	model	model	NN
cord-260708-l9w5jhsw	154	16	proposed	propose	VBN
cord-260708-l9w5jhsw	154	17	for	for	IN
cord-260708-l9w5jhsw	154	18	processing	processing	NN
cord-260708-l9w5jhsw	154	19	of	of	IN
cord-260708-l9w5jhsw	154	20	the	the	DT
cord-260708-l9w5jhsw	154	21	M	M	NNP
cord-260708-l9w5jhsw	154	22	polyprotein	polyprotein	NN
cord-260708-l9w5jhsw	154	23	described	describe	VBN
cord-260708-l9w5jhsw	154	24	above	above	RB
cord-260708-l9w5jhsw	154	25	for	for	IN
cord-260708-l9w5jhsw	154	26	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	154	27	holds	hold	VBZ
cord-260708-l9w5jhsw	154	28	true	true	JJ
cord-260708-l9w5jhsw	154	29	for	for	IN
cord-260708-l9w5jhsw	154	30	the	the	DT
cord-260708-l9w5jhsw	154	31	other	other	JJ
cord-260708-l9w5jhsw	154	32	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	154	33	;	;	:
cord-260708-l9w5jhsw	154	34	M	M	NNP
cord-260708-l9w5jhsw	154	35	polyproteins	polyprotein	NNS
cord-260708-l9w5jhsw	154	36	show	show	VBP
cord-260708-l9w5jhsw	154	37	similar	similar	JJ
cord-260708-l9w5jhsw	154	38	membrane	membrane	NN
cord-260708-l9w5jhsw	154	39	topology	topology	NN
cord-260708-l9w5jhsw	154	40	,	,	,
cord-260708-l9w5jhsw	154	41	with	with	IN
cord-260708-l9w5jhsw	154	42	six	six	CD
cord-260708-l9w5jhsw	154	43	transmembrane	transmembrane	NN
cord-260708-l9w5jhsw	154	44	regions	region	NNS
cord-260708-l9w5jhsw	154	45	and	and	CC
cord-260708-l9w5jhsw	154	46	conserved	conserved	JJ
cord-260708-l9w5jhsw	154	47	signalase	signalase	NN
cord-260708-l9w5jhsw	154	48	cleavage	cleavage	NN
cord-260708-l9w5jhsw	154	49	sites	site	NNS
cord-260708-l9w5jhsw	154	50	after	after	IN
cord-260708-l9w5jhsw	154	51	the	the	DT
cord-260708-l9w5jhsw	154	52	transmembrane	transmembrane	NN
cord-260708-l9w5jhsw	154	53	domains	domain	NNS
cord-260708-l9w5jhsw	154	54	TM	TM	NNP
cord-260708-l9w5jhsw	154	55	0	0	NNP
cord-260708-l9w5jhsw	154	56	,	,	,
cord-260708-l9w5jhsw	154	57	TM	TM	NNP
cord-260708-l9w5jhsw	154	58	2	2	CD
cord-260708-l9w5jhsw	154	59	and	and	CC
cord-260708-l9w5jhsw	154	60	TM	TM	NNP
cord-260708-l9w5jhsw	154	61	4	4	CD
cord-260708-l9w5jhsw	154	62	(	(	-LRB-
cord-260708-l9w5jhsw	154	63	Fig	Fig	NNP
cord-260708-l9w5jhsw	154	64	.	.	.
cord-260708-l9w5jhsw	154	65	3	3	CD
cord-260708-l9w5jhsw	154	66	)	)	-RRB-
cord-260708-l9w5jhsw	154	67	.	.	.
cord-260708-l9w5jhsw	155	1	Glycoprotein	glycoprotein	NN
cord-260708-l9w5jhsw	155	2	maturation	maturation	NN
cord-260708-l9w5jhsw	155	3	from	from	IN
cord-260708-l9w5jhsw	155	4	precursor	precursor	NN
cord-260708-l9w5jhsw	155	5	proteins	protein	NNS
cord-260708-l9w5jhsw	155	6	has	have	VBZ
cord-260708-l9w5jhsw	155	7	also	also	RB
cord-260708-l9w5jhsw	155	8	been	be	VBN
cord-260708-l9w5jhsw	155	9	observed	observe	VBN
cord-260708-l9w5jhsw	155	10	for	for	IN
cord-260708-l9w5jhsw	155	11	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	155	12	,	,	,
cord-260708-l9w5jhsw	155	13	where	where	WRB
cord-260708-l9w5jhsw	155	14	PreGn	pregn	PRP
cord-260708-l9w5jhsw	155	15	is	be	VBZ
cord-260708-l9w5jhsw	155	16	around	around	RB
cord-260708-l9w5jhsw	155	17	70	70	CD
cord-260708-l9w5jhsw	155	18	kDa	kDa	NNS
cord-260708-l9w5jhsw	155	19	and	and	CC
cord-260708-l9w5jhsw	155	20	PreGc	PreGc	NNPS
cord-260708-l9w5jhsw	155	21	around	around	RB
cord-260708-l9w5jhsw	155	22	85	85	CD
cord-260708-l9w5jhsw	155	23	kDa	kDa	NNPS
cord-260708-l9w5jhsw	155	24	[	[	-LRB-
cord-260708-l9w5jhsw	155	25	107	107	CD
cord-260708-l9w5jhsw	155	26	]	]	-RRB-
cord-260708-l9w5jhsw	155	27	.	.	.
cord-260708-l9w5jhsw	156	1	An	an	DT
cord-260708-l9w5jhsw	156	2	exception	exception	NN
cord-260708-l9w5jhsw	156	3	to	to	IN
cord-260708-l9w5jhsw	156	4	this	this	DT
cord-260708-l9w5jhsw	156	5	general	general	JJ
cord-260708-l9w5jhsw	156	6	similarity	similarity	NN
cord-260708-l9w5jhsw	156	7	is	be	VBZ
cord-260708-l9w5jhsw	156	8	Erve	Erve	NNP
cord-260708-l9w5jhsw	156	9	virus	virus	NN
cord-260708-l9w5jhsw	156	10	(	(	-LRB-
cord-260708-l9w5jhsw	156	11	ERVEV	ERVEV	NNP
cord-260708-l9w5jhsw	156	12	)	)	-RRB-
cord-260708-l9w5jhsw	156	13	,	,	,
cord-260708-l9w5jhsw	156	14	which	which	WDT
cord-260708-l9w5jhsw	156	15	does	do	VBZ
cord-260708-l9w5jhsw	156	16	not	not	RB
cord-260708-l9w5jhsw	156	17	contain	contain	VB
cord-260708-l9w5jhsw	156	18	TM	TM	NNP
cord-260708-l9w5jhsw	156	19	3	3	CD
cord-260708-l9w5jhsw	156	20	and	and	CC
cord-260708-l9w5jhsw	156	21	TM	TM	NNP
cord-260708-l9w5jhsw	156	22	4	4	CD
cord-260708-l9w5jhsw	156	23	,	,	,
cord-260708-l9w5jhsw	156	24	its	-PRON-	PRP$
cord-260708-l9w5jhsw	156	25	M	M	NNP
cord-260708-l9w5jhsw	156	26	polyprotein	polyprotein	NN
cord-260708-l9w5jhsw	156	27	lacking	lack	VBG
cord-260708-l9w5jhsw	156	28	the	the	DT
cord-260708-l9w5jhsw	156	29	entire	entire	JJ
cord-260708-l9w5jhsw	156	30	amino	amino	NN
cord-260708-l9w5jhsw	156	31	acid	acid	NN
cord-260708-l9w5jhsw	156	32	sequence	sequence	NN
cord-260708-l9w5jhsw	156	33	between	between	IN
cord-260708-l9w5jhsw	156	34	TM	TM	NNP
cord-260708-l9w5jhsw	156	35	2	2	CD
cord-260708-l9w5jhsw	156	36	and	and	CC
cord-260708-l9w5jhsw	156	37	the	the	DT
cord-260708-l9w5jhsw	156	38	Gc	Gc	NNP
cord-260708-l9w5jhsw	156	39	ectodomain	ectodomain	NNP
cord-260708-l9w5jhsw	156	40	.	.	.
cord-260708-l9w5jhsw	157	1	This	this	DT
cord-260708-l9w5jhsw	157	2	suggests	suggest	VBZ
cord-260708-l9w5jhsw	157	3	that	that	IN
cord-260708-l9w5jhsw	157	4	ERVEV	ERVEV	NNP
cord-260708-l9w5jhsw	157	5	lacks	lack	VBZ
cord-260708-l9w5jhsw	157	6	an	an	DT
cord-260708-l9w5jhsw	157	7	NS	NS	NNP
cord-260708-l9w5jhsw	157	8	M	M	NNP
cord-260708-l9w5jhsw	157	9	protein	protein	NN
cord-260708-l9w5jhsw	157	10	.	.	.
cord-260708-l9w5jhsw	158	1	Most	Most	JJS
cord-260708-l9w5jhsw	158	2	of	of	IN
cord-260708-l9w5jhsw	158	3	the	the	DT
cord-260708-l9w5jhsw	158	4	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	158	5	for	for	IN
cord-260708-l9w5jhsw	158	6	which	which	WDT
cord-260708-l9w5jhsw	158	7	we	-PRON-	PRP
cord-260708-l9w5jhsw	158	8	have	have	VBP
cord-260708-l9w5jhsw	158	9	sequence	sequence	NN
cord-260708-l9w5jhsw	158	10	data	datum	NNS
cord-260708-l9w5jhsw	158	11	appear	appear	VBP
cord-260708-l9w5jhsw	158	12	to	to	TO
cord-260708-l9w5jhsw	158	13	have	have	VB
cord-260708-l9w5jhsw	158	14	a	a	DT
cord-260708-l9w5jhsw	158	15	PreGn	pregn	NN
cord-260708-l9w5jhsw	158	16	domain	domain	NN
cord-260708-l9w5jhsw	158	17	that	that	WDT
cord-260708-l9w5jhsw	158	18	is	be	VBZ
cord-260708-l9w5jhsw	158	19	about	about	RB
cord-260708-l9w5jhsw	158	20	120	120	CD
cord-260708-l9w5jhsw	158	21	amino	amino	JJ
cord-260708-l9w5jhsw	158	22	acids	acid	NNS
cord-260708-l9w5jhsw	158	23	shorter	short	JJR
cord-260708-l9w5jhsw	158	24	than	than	IN
cord-260708-l9w5jhsw	158	25	that	that	DT
cord-260708-l9w5jhsw	158	26	seen	see	VBN
cord-260708-l9w5jhsw	158	27	in	in	IN
cord-260708-l9w5jhsw	158	28	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	158	29	,	,	,
cord-260708-l9w5jhsw	158	30	due	due	IN
cord-260708-l9w5jhsw	158	31	to	to	IN
cord-260708-l9w5jhsw	158	32	a	a	DT
cord-260708-l9w5jhsw	158	33	much	much	RB
cord-260708-l9w5jhsw	158	34	shorter	short	JJR
cord-260708-l9w5jhsw	158	35	mucin	mucin	NN
cord-260708-l9w5jhsw	158	36	-	-	HYPH
cord-260708-l9w5jhsw	158	37	like	like	JJ
cord-260708-l9w5jhsw	158	38	domain	domain	NN
cord-260708-l9w5jhsw	158	39	,	,	,
cord-260708-l9w5jhsw	158	40	as	as	IN
cord-260708-l9w5jhsw	158	41	was	be	VBD
cord-260708-l9w5jhsw	158	42	previously	previously	RB
cord-260708-l9w5jhsw	158	43	described	describe	VBN
cord-260708-l9w5jhsw	158	44	for	for	IN
cord-260708-l9w5jhsw	158	45	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	158	46	[	[	-LRB-
cord-260708-l9w5jhsw	158	47	144	144	CD
cord-260708-l9w5jhsw	158	48	]	]	-RRB-
cord-260708-l9w5jhsw	158	49	.	.	.
cord-260708-l9w5jhsw	159	1	Another	another	DT
cord-260708-l9w5jhsw	159	2	difference	difference	NN
cord-260708-l9w5jhsw	159	3	is	be	VBZ
cord-260708-l9w5jhsw	159	4	that	that	IN
cord-260708-l9w5jhsw	159	5	other	other	JJ
cord-260708-l9w5jhsw	159	6	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	159	7	do	do	VBP
cord-260708-l9w5jhsw	159	8	not	not	RB
cord-260708-l9w5jhsw	159	9	contain	contain	VB
cord-260708-l9w5jhsw	159	10	a	a	DT
cord-260708-l9w5jhsw	159	11	furin	furin	NN
cord-260708-l9w5jhsw	159	12	-	-	HYPH
cord-260708-l9w5jhsw	159	13	cleavage	cleavage	NN
cord-260708-l9w5jhsw	159	14	site	site	NN
cord-260708-l9w5jhsw	159	15	(	(	-LRB-
cord-260708-l9w5jhsw	159	16	RSKR	RSKR	NNP
cord-260708-l9w5jhsw	159	17	)	)	-RRB-
cord-260708-l9w5jhsw	159	18	following	follow	VBG
cord-260708-l9w5jhsw	159	19	the	the	DT
cord-260708-l9w5jhsw	159	20	O	o	NN
cord-260708-l9w5jhsw	159	21	-	-	HYPH
cord-260708-l9w5jhsw	159	22	glycosylated	glycosylate	VBN
cord-260708-l9w5jhsw	159	23	mucin	mucin	NN
cord-260708-l9w5jhsw	159	24	-	-	HYPH
cord-260708-l9w5jhsw	159	25	like	like	JJ
cord-260708-l9w5jhsw	159	26	domain	domain	NN
cord-260708-l9w5jhsw	159	27	.	.	.
cord-260708-l9w5jhsw	160	1	The	the	DT
cord-260708-l9w5jhsw	160	2	SKI-1	SKI-1	NNP
cord-260708-l9w5jhsw	160	3	/	/	SYM
cord-260708-l9w5jhsw	160	4	S1P	s1p	NN
cord-260708-l9w5jhsw	160	5	-	-	HYPH
cord-260708-l9w5jhsw	160	6	like	like	JJ
cord-260708-l9w5jhsw	160	7	protease	protease	NN
cord-260708-l9w5jhsw	160	8	cleavage	cleavage	NN
cord-260708-l9w5jhsw	160	9	tetrapeptides	tetrapeptide	NNS
cord-260708-l9w5jhsw	160	10	in	in	IN
cord-260708-l9w5jhsw	160	11	many	many	JJ
cord-260708-l9w5jhsw	160	12	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	160	13	appear	appear	VBP
cord-260708-l9w5jhsw	160	14	to	to	TO
cord-260708-l9w5jhsw	160	15	be	be	VB
cord-260708-l9w5jhsw	160	16	different	different	JJ
cord-260708-l9w5jhsw	160	17	to	to	IN
cord-260708-l9w5jhsw	160	18	those	those	DT
cord-260708-l9w5jhsw	160	19	proposed	propose	VBN
cord-260708-l9w5jhsw	160	20	for	for	IN
cord-260708-l9w5jhsw	160	21	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	160	22	;	;	:
cord-260708-l9w5jhsw	160	23	however	however	RB
cord-260708-l9w5jhsw	160	24	,	,	,
cord-260708-l9w5jhsw	160	25	all	all	DT
cord-260708-l9w5jhsw	160	26	appear	appear	VBP
cord-260708-l9w5jhsw	160	27	to	to	TO
cord-260708-l9w5jhsw	160	28	fit	fit	VB
cord-260708-l9w5jhsw	160	29	the	the	DT
cord-260708-l9w5jhsw	160	30	consensus	consensus	NN
cord-260708-l9w5jhsw	160	31	subtilisin	subtilisin	NNP
cord-260708-l9w5jhsw	160	32	cleavage	cleavage	NN
cord-260708-l9w5jhsw	160	33	sequence	sequence	NN
cord-260708-l9w5jhsw	160	34	(	(	-LRB-
cord-260708-l9w5jhsw	160	35	R	R	NNP
cord-260708-l9w5jhsw	160	36	/	/	SYM
cord-260708-l9w5jhsw	160	37	K)X(hydrophobic)Z	K)X(hydrophobic)Z	NNP
cord-260708-l9w5jhsw	160	38	;	;	:
cord-260708-l9w5jhsw	160	39	(	(	-LRB-
cord-260708-l9w5jhsw	160	40	where	where	WRB
cord-260708-l9w5jhsw	160	41	X	x	NN
cord-260708-l9w5jhsw	160	42	is	be	VBZ
cord-260708-l9w5jhsw	160	43	any	any	DT
cord-260708-l9w5jhsw	160	44	amino	amino	NN
cord-260708-l9w5jhsw	160	45	acid	acid	NN
cord-260708-l9w5jhsw	160	46	and	and	CC
cord-260708-l9w5jhsw	160	47	Z	z	NN
cord-260708-l9w5jhsw	161	1	is	be	VBZ
cord-260708-l9w5jhsw	161	2	preferably	preferably	RB
cord-260708-l9w5jhsw	161	3	F	F	NNP
cord-260708-l9w5jhsw	161	4	,	,	,
cord-260708-l9w5jhsw	161	5	K	K	NNP
cord-260708-l9w5jhsw	161	6	,	,	,
cord-260708-l9w5jhsw	161	7	L	L	NNP
cord-260708-l9w5jhsw	161	8	or	or	CC
cord-260708-l9w5jhsw	161	9	T	T	NNP
cord-260708-l9w5jhsw	161	10	but	but	CC
cord-260708-l9w5jhsw	161	11	not	not	RB
cord-260708-l9w5jhsw	161	12	V	v	NN
cord-260708-l9w5jhsw	161	13	,	,	,
cord-260708-l9w5jhsw	161	14	P	p	NN
cord-260708-l9w5jhsw	161	15	,	,	,
cord-260708-l9w5jhsw	161	16	E	E	NNP
cord-260708-l9w5jhsw	161	17	,	,	,
cord-260708-l9w5jhsw	161	18	D	D	NNP
cord-260708-l9w5jhsw	161	19	,	,	,
cord-260708-l9w5jhsw	161	20	C	C	NNP
cord-260708-l9w5jhsw	161	21	)	)	-RRB-
cord-260708-l9w5jhsw	162	1	[	[	-LRB-
cord-260708-l9w5jhsw	162	2	56	56	CD
cord-260708-l9w5jhsw	162	3	]	]	-RRB-
cord-260708-l9w5jhsw	162	4	.	.	.
cord-260708-l9w5jhsw	163	1	This	this	DT
cord-260708-l9w5jhsw	163	2	may	may	MD
cord-260708-l9w5jhsw	163	3	reflect	reflect	VB
cord-260708-l9w5jhsw	163	4	differences	difference	NNS
cord-260708-l9w5jhsw	163	5	in	in	IN
cord-260708-l9w5jhsw	163	6	adaptation	adaptation	NN
cord-260708-l9w5jhsw	163	7	to	to	IN
cord-260708-l9w5jhsw	163	8	specific	specific	JJ
cord-260708-l9w5jhsw	163	9	tick	tick	NN
cord-260708-l9w5jhsw	163	10	or	or	CC
cord-260708-l9w5jhsw	163	11	mammalian	mammalian	JJ
cord-260708-l9w5jhsw	163	12	hosts	host	NNS
cord-260708-l9w5jhsw	163	13	,	,	,
cord-260708-l9w5jhsw	163	14	and	and	CC
cord-260708-l9w5jhsw	163	15	further	further	JJ
cord-260708-l9w5jhsw	163	16	studies	study	NNS
cord-260708-l9w5jhsw	163	17	on	on	IN
cord-260708-l9w5jhsw	163	18	the	the	DT
cord-260708-l9w5jhsw	163	19	importance	importance	NN
cord-260708-l9w5jhsw	163	20	of	of	IN
cord-260708-l9w5jhsw	163	21	these	these	DT
cord-260708-l9w5jhsw	163	22	various	various	JJ
cord-260708-l9w5jhsw	163	23	stages	stage	NNS
cord-260708-l9w5jhsw	163	24	in	in	IN
cord-260708-l9w5jhsw	163	25	the	the	DT
cord-260708-l9w5jhsw	163	26	maturation	maturation	NN
cord-260708-l9w5jhsw	163	27	of	of	IN
cord-260708-l9w5jhsw	163	28	the	the	DT
cord-260708-l9w5jhsw	163	29	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	163	30	for	for	IN
cord-260708-l9w5jhsw	163	31	different	different	JJ
cord-260708-l9w5jhsw	163	32	hosts	host	NNS
cord-260708-l9w5jhsw	163	33	are	be	VBP
cord-260708-l9w5jhsw	163	34	clearly	clearly	RB
cord-260708-l9w5jhsw	163	35	required	require	VBN
cord-260708-l9w5jhsw	163	36	.	.	.
cord-260708-l9w5jhsw	164	1	The	the	DT
cord-260708-l9w5jhsw	164	2	L	L	NNP
cord-260708-l9w5jhsw	164	3	segment	segment	NN
cord-260708-l9w5jhsw	164	4	of	of	IN
cord-260708-l9w5jhsw	164	5	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	164	6	,	,	,
cord-260708-l9w5jhsw	164	7	which	which	WDT
cord-260708-l9w5jhsw	164	8	contains	contain	VBZ
cord-260708-l9w5jhsw	164	9	a	a	DT
cord-260708-l9w5jhsw	164	10	single	single	JJ
cord-260708-l9w5jhsw	164	11	open	open	JJ
cord-260708-l9w5jhsw	164	12	reading	reading	NN
cord-260708-l9w5jhsw	164	13	frame	frame	NN
cord-260708-l9w5jhsw	164	14	(	(	-LRB-
cord-260708-l9w5jhsw	164	15	ORF	ORF	NNP
cord-260708-l9w5jhsw	164	16	)	)	-RRB-
cord-260708-l9w5jhsw	164	17	of	of	IN
cord-260708-l9w5jhsw	164	18	approximately	approximately	RB
cord-260708-l9w5jhsw	164	19	12	12	CD
cord-260708-l9w5jhsw	164	20	kb	kb	NNS
cord-260708-l9w5jhsw	164	21	,	,	,
cord-260708-l9w5jhsw	164	22	encoding	encode	VBG
cord-260708-l9w5jhsw	164	23	a	a	DT
cord-260708-l9w5jhsw	164	24	protein	protein	NN
cord-260708-l9w5jhsw	164	25	of	of	IN
cord-260708-l9w5jhsw	164	26	approximately	approximately	RB
cord-260708-l9w5jhsw	164	27	450	450	CD
cord-260708-l9w5jhsw	164	28	kDa	kDa	NNS
cord-260708-l9w5jhsw	164	29	,	,	,
cord-260708-l9w5jhsw	164	30	is	be	VBZ
cord-260708-l9w5jhsw	164	31	almost	almost	RB
cord-260708-l9w5jhsw	164	32	twice	twice	RB
cord-260708-l9w5jhsw	164	33	as	as	RB
cord-260708-l9w5jhsw	164	34	long	long	RB
cord-260708-l9w5jhsw	164	35	as	as	IN
cord-260708-l9w5jhsw	164	36	the	the	DT
cord-260708-l9w5jhsw	164	37	L	l	NN
cord-260708-l9w5jhsw	164	38	proteins	protein	NNS
cord-260708-l9w5jhsw	164	39	of	of	IN
cord-260708-l9w5jhsw	164	40	most	most	JJS
cord-260708-l9w5jhsw	164	41	other	other	JJ
cord-260708-l9w5jhsw	164	42	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	164	43	,	,	,
cord-260708-l9w5jhsw	164	44	with	with	IN
cord-260708-l9w5jhsw	164	45	the	the	DT
cord-260708-l9w5jhsw	164	46	exception	exception	NN
cord-260708-l9w5jhsw	164	47	of	of	IN
cord-260708-l9w5jhsw	164	48	the	the	DT
cord-260708-l9w5jhsw	164	49	tospoviruses	tospoviruse	NNS
cord-260708-l9w5jhsw	164	50	,	,	,
cord-260708-l9w5jhsw	164	51	in	in	IN
cord-260708-l9w5jhsw	164	52	which	which	WDT
cord-260708-l9w5jhsw	164	53	the	the	DT
cord-260708-l9w5jhsw	164	54	L	L	NNP
cord-260708-l9w5jhsw	164	55	segment	segment	NN
cord-260708-l9w5jhsw	164	56	is	be	VBZ
cord-260708-l9w5jhsw	164	57	approximately	approximately	RB
cord-260708-l9w5jhsw	164	58	9	9	CD
cord-260708-l9w5jhsw	164	59	kb	kb	NNS
cord-260708-l9w5jhsw	164	60	in	in	IN
cord-260708-l9w5jhsw	164	61	length	length	NN
cord-260708-l9w5jhsw	164	62	[	[	-LRB-
cord-260708-l9w5jhsw	164	63	48	48	CD
cord-260708-l9w5jhsw	164	64	,	,	,
cord-260708-l9w5jhsw	164	65	85	85	CD
cord-260708-l9w5jhsw	164	66	,	,	,
cord-260708-l9w5jhsw	164	67	94	94	CD
cord-260708-l9w5jhsw	164	68	,	,	,
cord-260708-l9w5jhsw	164	69	108	108	CD
cord-260708-l9w5jhsw	164	70	]	]	-RRB-
cord-260708-l9w5jhsw	165	1	(	(	-LRB-
cord-260708-l9w5jhsw	165	2	Fig	Fig	NNP
cord-260708-l9w5jhsw	165	3	.	.	.
cord-260708-l9w5jhsw	166	1	4	4	LS
cord-260708-l9w5jhsw	166	2	)	)	-RRB-
cord-260708-l9w5jhsw	166	3	.	.	.
cord-260708-l9w5jhsw	167	1	Despite	despite	IN
cord-260708-l9w5jhsw	167	2	this	this	DT
cord-260708-l9w5jhsw	167	3	difference	difference	NN
cord-260708-l9w5jhsw	167	4	in	in	IN
cord-260708-l9w5jhsw	167	5	length	length	NN
cord-260708-l9w5jhsw	167	6	and	and	CC
cord-260708-l9w5jhsw	167	7	sequence	sequence	NN
cord-260708-l9w5jhsw	167	8	,	,	,
cord-260708-l9w5jhsw	167	9	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	167	10	L	L	NNP
cord-260708-l9w5jhsw	167	11	proteins	protein	NNS
cord-260708-l9w5jhsw	167	12	still	still	RB
cord-260708-l9w5jhsw	167	13	show	show	VBP
cord-260708-l9w5jhsw	167	14	the	the	DT
cord-260708-l9w5jhsw	167	15	four	four	CD
cord-260708-l9w5jhsw	167	16	conserved	conserved	JJ
cord-260708-l9w5jhsw	167	17	functional	functional	JJ
cord-260708-l9w5jhsw	167	18	regions	region	NNS
cord-260708-l9w5jhsw	167	19	previously	previously	RB
cord-260708-l9w5jhsw	167	20	described	describe	VBN
cord-260708-l9w5jhsw	167	21	for	for	IN
cord-260708-l9w5jhsw	167	22	other	other	JJ
cord-260708-l9w5jhsw	167	23	bunyavirus	bunyavirus	NNP
cord-260708-l9w5jhsw	167	24	L	l	NN
cord-260708-l9w5jhsw	167	25	proteins	protein	NNS
cord-260708-l9w5jhsw	167	26	[	[	-LRB-
cord-260708-l9w5jhsw	167	27	94	94	CD
cord-260708-l9w5jhsw	167	28	,	,	,
cord-260708-l9w5jhsw	167	29	108	108	CD
cord-260708-l9w5jhsw	167	30	,	,	,
cord-260708-l9w5jhsw	167	31	131	131	CD
cord-260708-l9w5jhsw	167	32	,	,	,
cord-260708-l9w5jhsw	167	33	139	139	CD
cord-260708-l9w5jhsw	167	34	,	,	,
cord-260708-l9w5jhsw	167	35	177	177	CD
cord-260708-l9w5jhsw	167	36	]	]	-RRB-
cord-260708-l9w5jhsw	167	37	.	.	.
cord-260708-l9w5jhsw	168	1	The	the	DT
cord-260708-l9w5jhsw	168	2	bunyavirus	bunyavirus	NNP
cord-260708-l9w5jhsw	168	3	L	l	NN
cord-260708-l9w5jhsw	168	4	proteins	protein	NNS
cord-260708-l9w5jhsw	168	5	contain	contain	VBP
cord-260708-l9w5jhsw	168	6	the	the	DT
cord-260708-l9w5jhsw	168	7	RNA	RNA	NNP
cord-260708-l9w5jhsw	168	8	-	-	HYPH
cord-260708-l9w5jhsw	168	9	dependent	dependent	JJ
cord-260708-l9w5jhsw	168	10	RNA	RNA	NNP
cord-260708-l9w5jhsw	168	11	polymerase	polymerase	NN
cord-260708-l9w5jhsw	168	12	(	(	-LRB-
cord-260708-l9w5jhsw	168	13	RdRp	RdRp	NNP
cord-260708-l9w5jhsw	168	14	)	)	-RRB-
cord-260708-l9w5jhsw	168	15	,	,	,
cord-260708-l9w5jhsw	168	16	and	and	CC
cord-260708-l9w5jhsw	168	17	the	the	DT
cord-260708-l9w5jhsw	168	18	most	most	RBS
cord-260708-l9w5jhsw	168	19	conserved	conserved	JJ
cord-260708-l9w5jhsw	168	20	region	region	NN
cord-260708-l9w5jhsw	168	21	of	of	IN
cord-260708-l9w5jhsw	168	22	the	the	DT
cord-260708-l9w5jhsw	168	23	L	L	NNP
cord-260708-l9w5jhsw	168	24	segment	segment	NN
cord-260708-l9w5jhsw	168	25	among	among	IN
cord-260708-l9w5jhsw	168	26	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	168	27	is	be	VBZ
cord-260708-l9w5jhsw	168	28	the	the	DT
cord-260708-l9w5jhsw	168	29	region	region	NN
cord-260708-l9w5jhsw	168	30	corresponding	correspond	VBG
cord-260708-l9w5jhsw	168	31	to	to	IN
cord-260708-l9w5jhsw	168	32	the	the	DT
cord-260708-l9w5jhsw	168	33	coding	code	VBG
cord-260708-l9w5jhsw	168	34	sequence	sequence	NN
cord-260708-l9w5jhsw	168	35	for	for	IN
cord-260708-l9w5jhsw	168	36	the	the	DT
cord-260708-l9w5jhsw	168	37	core	core	NN
cord-260708-l9w5jhsw	168	38	catalytic	catalytic	JJ
cord-260708-l9w5jhsw	168	39	domains	domain	NNS
cord-260708-l9w5jhsw	168	40	of	of	IN
cord-260708-l9w5jhsw	168	41	the	the	DT
cord-260708-l9w5jhsw	168	42	RdRp	RdRp	NNP
cord-260708-l9w5jhsw	168	43	[	[	-LRB-
cord-260708-l9w5jhsw	168	44	8	8	CD
cord-260708-l9w5jhsw	168	45	,	,	,
cord-260708-l9w5jhsw	168	46	85	85	CD
cord-260708-l9w5jhsw	168	47	,	,	,
cord-260708-l9w5jhsw	168	48	108	108	CD
cord-260708-l9w5jhsw	168	49	]	]	-RRB-
cord-260708-l9w5jhsw	168	50	.	.	.
cord-260708-l9w5jhsw	169	1	Within	within	IN
cord-260708-l9w5jhsw	169	2	this	this	DT
cord-260708-l9w5jhsw	169	3	polymerase	polymerase	NN
cord-260708-l9w5jhsw	169	4	module	module	NN
cord-260708-l9w5jhsw	169	5	(	(	-LRB-
cord-260708-l9w5jhsw	169	6	also	also	RB
cord-260708-l9w5jhsw	169	7	called	call	VBN
cord-260708-l9w5jhsw	169	8	region	region	NN
cord-260708-l9w5jhsw	169	9	3	3	CD
cord-260708-l9w5jhsw	169	10	)	)	-RRB-
cord-260708-l9w5jhsw	169	11	can	can	MD
cord-260708-l9w5jhsw	169	12	be	be	VB
cord-260708-l9w5jhsw	169	13	distinguished	distinguish	VBN
cord-260708-l9w5jhsw	169	14	six	six	CD
cord-260708-l9w5jhsw	169	15	conserved	conserve	VBN
cord-260708-l9w5jhsw	169	16	motifs	motif	NNS
cord-260708-l9w5jhsw	169	17	[	[	-LRB-
cord-260708-l9w5jhsw	169	18	94	94	CD
cord-260708-l9w5jhsw	169	19	,	,	,
cord-260708-l9w5jhsw	169	20	108	108	CD
cord-260708-l9w5jhsw	169	21	]	]	-RRB-
cord-260708-l9w5jhsw	170	1	(	(	-LRB-
cord-260708-l9w5jhsw	170	2	Fig	Fig	NNP
cord-260708-l9w5jhsw	170	3	.	.	NNP
cord-260708-l9w5jhsw	170	4	4	4	CD
cord-260708-l9w5jhsw	170	5	)	)	-RRB-
cord-260708-l9w5jhsw	170	6	.	.	.
cord-260708-l9w5jhsw	171	1	Motifs	Motifs	NNP
cord-260708-l9w5jhsw	172	1	A	a	DT
cord-260708-l9w5jhsw	172	2	through	through	IN
cord-260708-l9w5jhsw	172	3	D	d	NN
cord-260708-l9w5jhsw	172	4	are	be	VBP
cord-260708-l9w5jhsw	172	5	conserved	conserve	VBN
cord-260708-l9w5jhsw	172	6	among	among	IN
cord-260708-l9w5jhsw	172	7	all	all	DT
cord-260708-l9w5jhsw	172	8	RNA	rna	NN
cord-260708-l9w5jhsw	172	9	-	-	HYPH
cord-260708-l9w5jhsw	172	10	dependent	dependent	JJ
cord-260708-l9w5jhsw	172	11	polymerases	polymerase	NNS
cord-260708-l9w5jhsw	172	12	[	[	-LRB-
cord-260708-l9w5jhsw	172	13	50	50	CD
cord-260708-l9w5jhsw	172	14	,	,	,
cord-260708-l9w5jhsw	172	15	129	129	CD
cord-260708-l9w5jhsw	172	16	]	]	-RRB-
cord-260708-l9w5jhsw	172	17	;	;	:
cord-260708-l9w5jhsw	172	18	motif	motif	NN
cord-260708-l9w5jhsw	172	19	pre	pre	VBN
cord-260708-l9w5jhsw	172	20	-	-	JJ
cord-260708-l9w5jhsw	172	21	A	a	JJ
cord-260708-l9w5jhsw	172	22	,	,	,
cord-260708-l9w5jhsw	172	23	upstream	upstream	RB
cord-260708-l9w5jhsw	172	24	of	of	IN
cord-260708-l9w5jhsw	172	25	motif	motif	NN
cord-260708-l9w5jhsw	172	26	A	a	NN
cord-260708-l9w5jhsw	172	27	,	,	,
cord-260708-l9w5jhsw	172	28	is	be	VBZ
cord-260708-l9w5jhsw	172	29	present	present	JJ
cord-260708-l9w5jhsw	172	30	in	in	IN
cord-260708-l9w5jhsw	172	31	all	all	DT
cord-260708-l9w5jhsw	172	32	RNA	RNA	NNP
cord-260708-l9w5jhsw	172	33	-	-	HYPH
cord-260708-l9w5jhsw	172	34	dependent	dependent	JJ
cord-260708-l9w5jhsw	172	35	RNA	RNA	NNP
cord-260708-l9w5jhsw	172	36	polymerases	polymerase	NNS
cord-260708-l9w5jhsw	172	37	and	and	CC
cord-260708-l9w5jhsw	172	38	reverse	reverse	VB
cord-260708-l9w5jhsw	172	39	transcriptases	transcriptase	NNS
cord-260708-l9w5jhsw	172	40	,	,	,
cord-260708-l9w5jhsw	172	41	and	and	CC
cord-260708-l9w5jhsw	172	42	motif	motif	NN
cord-260708-l9w5jhsw	172	43	E	e	NN
cord-260708-l9w5jhsw	172	44	,	,	,
cord-260708-l9w5jhsw	172	45	which	which	WDT
cord-260708-l9w5jhsw	172	46	is	be	VBZ
cord-260708-l9w5jhsw	172	47	downstream	downstream	JJ
cord-260708-l9w5jhsw	172	48	of	of	IN
cord-260708-l9w5jhsw	172	49	motif	motif	NN
cord-260708-l9w5jhsw	172	50	D	d	NN
cord-260708-l9w5jhsw	172	51	,	,	,
cord-260708-l9w5jhsw	172	52	is	be	VBZ
cord-260708-l9w5jhsw	172	53	conserved	conserve	VBN
cord-260708-l9w5jhsw	172	54	in	in	IN
cord-260708-l9w5jhsw	172	55	segmented	segmented	JJ
cord-260708-l9w5jhsw	172	56	negative	negative	JJ
cord-260708-l9w5jhsw	172	57	-	-	HYPH
cord-260708-l9w5jhsw	172	58	strand	strand	NN
cord-260708-l9w5jhsw	172	59	RNA	RNA	NNP
cord-260708-l9w5jhsw	172	60	viruses	virus	NNS
cord-260708-l9w5jhsw	172	61	[	[	-LRB-
cord-260708-l9w5jhsw	172	62	114	114	CD
cord-260708-l9w5jhsw	172	63	,	,	,
cord-260708-l9w5jhsw	172	64	129	129	CD
cord-260708-l9w5jhsw	172	65	,	,	,
cord-260708-l9w5jhsw	172	66	186	186	CD
cord-260708-l9w5jhsw	172	67	]	]	-RRB-
cord-260708-l9w5jhsw	172	68	.	.	.
cord-260708-l9w5jhsw	173	1	Motifs	Motifs	NNP
cord-260708-l9w5jhsw	173	2	A	A	NNP
cord-260708-l9w5jhsw	173	3	,	,	,
cord-260708-l9w5jhsw	173	4	C	C	NNP
cord-260708-l9w5jhsw	173	5	and	and	CC
cord-260708-l9w5jhsw	173	6	D	D	NNP
cord-260708-l9w5jhsw	173	7	are	be	VBP
cord-260708-l9w5jhsw	173	8	predicted	predict	VBN
cord-260708-l9w5jhsw	173	9	to	to	TO
cord-260708-l9w5jhsw	173	10	bind	bind	VB
cord-260708-l9w5jhsw	173	11	nucleoside	nucleoside	JJ
cord-260708-l9w5jhsw	173	12	triphosphates	triphosphate	NNS
cord-260708-l9w5jhsw	173	13	(	(	-LRB-
cord-260708-l9w5jhsw	173	14	NTPs	ntp	NNS
cord-260708-l9w5jhsw	173	15	)	)	-RRB-
cord-260708-l9w5jhsw	173	16	and	and	CC
cord-260708-l9w5jhsw	173	17	are	be	VBP
cord-260708-l9w5jhsw	173	18	therefore	therefore	RB
cord-260708-l9w5jhsw	173	19	likely	likely	JJ
cord-260708-l9w5jhsw	173	20	to	to	TO
cord-260708-l9w5jhsw	173	21	be	be	VB
cord-260708-l9w5jhsw	173	22	involved	involve	VBN
cord-260708-l9w5jhsw	173	23	in	in	IN
cord-260708-l9w5jhsw	173	24	the	the	DT
cord-260708-l9w5jhsw	173	25	catalytic	catalytic	JJ
cord-260708-l9w5jhsw	173	26	functions	function	NNS
cord-260708-l9w5jhsw	173	27	of	of	IN
cord-260708-l9w5jhsw	173	28	the	the	DT
cord-260708-l9w5jhsw	173	29	polymerase	polymerase	NN
cord-260708-l9w5jhsw	173	30	[	[	-LRB-
cord-260708-l9w5jhsw	173	31	50	50	CD
cord-260708-l9w5jhsw	173	32	,	,	,
cord-260708-l9w5jhsw	173	33	114	114	CD
cord-260708-l9w5jhsw	173	34	]	]	-RRB-
cord-260708-l9w5jhsw	173	35	,	,	,
cord-260708-l9w5jhsw	173	36	while	while	IN
cord-260708-l9w5jhsw	173	37	motifs	motif	NNS
cord-260708-l9w5jhsw	173	38	B	b	NN
cord-260708-l9w5jhsw	173	39	and	and	CC
cord-260708-l9w5jhsw	173	40	E	E	NNS
cord-260708-l9w5jhsw	173	41	are	be	VBP
cord-260708-l9w5jhsw	173	42	predicted	predict	VBN
cord-260708-l9w5jhsw	173	43	to	to	TO
cord-260708-l9w5jhsw	173	44	take	take	VB
cord-260708-l9w5jhsw	173	45	part	part	NN
cord-260708-l9w5jhsw	173	46	in	in	IN
cord-260708-l9w5jhsw	173	47	template	template	NN
cord-260708-l9w5jhsw	173	48	and/or	and/or	CC
cord-260708-l9w5jhsw	173	49	primer	primer	NN
cord-260708-l9w5jhsw	173	50	positioning	position	VBG
cord-260708-l9w5jhsw	173	51	[	[	-LRB-
cord-260708-l9w5jhsw	173	52	114	114	CD
cord-260708-l9w5jhsw	173	53	]	]	-RRB-
cord-260708-l9w5jhsw	173	54	.	.	.
cord-260708-l9w5jhsw	174	1	Motif	motif	NN
cord-260708-l9w5jhsw	174	2	pre	pre	JJ
cord-260708-l9w5jhsw	174	3	-	-	JJ
cord-260708-l9w5jhsw	174	4	A	a	NN
cord-260708-l9w5jhsw	174	5	is	be	VBZ
cord-260708-l9w5jhsw	174	6	also	also	RB
cord-260708-l9w5jhsw	174	7	predicted	predict	VBN
cord-260708-l9w5jhsw	174	8	to	to	TO
cord-260708-l9w5jhsw	174	9	be	be	VB
cord-260708-l9w5jhsw	174	10	involved	involve	VBN
cord-260708-l9w5jhsw	174	11	in	in	IN
cord-260708-l9w5jhsw	174	12	template	template	NN
cord-260708-l9w5jhsw	174	13	positioning	positioning	NN
cord-260708-l9w5jhsw	174	14	[	[	-LRB-
cord-260708-l9w5jhsw	174	15	94	94	CD
cord-260708-l9w5jhsw	174	16	,	,	,
cord-260708-l9w5jhsw	174	17	114	114	CD
cord-260708-l9w5jhsw	174	18	]	]	-RRB-
cord-260708-l9w5jhsw	174	19	.	.	.
cord-260708-l9w5jhsw	175	1	The	the	DT
cord-260708-l9w5jhsw	175	2	fact	fact	NN
cord-260708-l9w5jhsw	175	3	that	that	IN
cord-260708-l9w5jhsw	175	4	the	the	DT
cord-260708-l9w5jhsw	175	5	inter	inter	JJ
cord-260708-l9w5jhsw	175	6	-	-	JJ
cord-260708-l9w5jhsw	175	7	motif	motif	JJ
cord-260708-l9w5jhsw	175	8	distances	distance	NNS
cord-260708-l9w5jhsw	175	9	are	be	VBP
cord-260708-l9w5jhsw	175	10	more	more	RBR
cord-260708-l9w5jhsw	175	11	or	or	CC
cord-260708-l9w5jhsw	175	12	less	less	RBR
cord-260708-l9w5jhsw	175	13	constant	constant	JJ
cord-260708-l9w5jhsw	175	14	suggests	suggest	VBZ
cord-260708-l9w5jhsw	175	15	that	that	IN
cord-260708-l9w5jhsw	175	16	the	the	DT
cord-260708-l9w5jhsw	175	17	polymerase	polymerase	NN
cord-260708-l9w5jhsw	175	18	module	module	NN
cord-260708-l9w5jhsw	175	19	functions	function	NNS
cord-260708-l9w5jhsw	175	20	in	in	IN
cord-260708-l9w5jhsw	175	21	a	a	DT
cord-260708-l9w5jhsw	175	22	structurally	structurally	RB
cord-260708-l9w5jhsw	175	23	dependent	dependent	JJ
cord-260708-l9w5jhsw	175	24	manner	manner	NN
cord-260708-l9w5jhsw	175	25	[	[	-LRB-
cord-260708-l9w5jhsw	175	26	94	94	CD
cord-260708-l9w5jhsw	175	27	]	]	-RRB-
cord-260708-l9w5jhsw	175	28	.	.	.
cord-260708-l9w5jhsw	176	1	Upstream	upstream	RB
cord-260708-l9w5jhsw	176	2	of	of	IN
cord-260708-l9w5jhsw	176	3	the	the	DT
cord-260708-l9w5jhsw	176	4	polymerase	polymerase	NN
cord-260708-l9w5jhsw	176	5	module	module	NN
cord-260708-l9w5jhsw	176	6	are	be	VBP
cord-260708-l9w5jhsw	176	7	regions	region	NNS
cord-260708-l9w5jhsw	176	8	1	1	CD
cord-260708-l9w5jhsw	176	9	and	and	CC
cord-260708-l9w5jhsw	176	10	2	2	CD
cord-260708-l9w5jhsw	177	1	(	(	-LRB-
cord-260708-l9w5jhsw	177	2	Fig	Fig	NNP
cord-260708-l9w5jhsw	177	3	.	.	NNP
cord-260708-l9w5jhsw	177	4	4	4	LS
cord-260708-l9w5jhsw	177	5	)	)	-RRB-
cord-260708-l9w5jhsw	177	6	which	which	WDT
cord-260708-l9w5jhsw	177	7	are	be	VBP
cord-260708-l9w5jhsw	177	8	conserved	conserve	VBN
cord-260708-l9w5jhsw	177	9	in	in	IN
cord-260708-l9w5jhsw	177	10	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	177	11	and	and	CC
cord-260708-l9w5jhsw	177	12	arenaviruses	arenaviruses	NNP
cord-260708-l9w5jhsw	177	13	[	[	-LRB-
cord-260708-l9w5jhsw	177	14	94	94	CD
cord-260708-l9w5jhsw	177	15	,	,	,
cord-260708-l9w5jhsw	177	16	114	114	CD
cord-260708-l9w5jhsw	177	17	]	]	-RRB-
cord-260708-l9w5jhsw	177	18	,	,	,
cord-260708-l9w5jhsw	177	19	while	while	IN
cord-260708-l9w5jhsw	177	20	downstream	downstream	RB
cord-260708-l9w5jhsw	177	21	of	of	IN
cord-260708-l9w5jhsw	177	22	the	the	DT
cord-260708-l9w5jhsw	177	23	polymerase	polymerase	NN
cord-260708-l9w5jhsw	177	24	module	module	NN
cord-260708-l9w5jhsw	177	25	is	be	VBZ
cord-260708-l9w5jhsw	177	26	region	region	NN
cord-260708-l9w5jhsw	177	27	4	4	CD
cord-260708-l9w5jhsw	178	1	(	(	-LRB-
cord-260708-l9w5jhsw	178	2	Fig	Fig	NNP
cord-260708-l9w5jhsw	178	3	.	.	NNP
cord-260708-l9w5jhsw	178	4	4	4	CD
cord-260708-l9w5jhsw	178	5	)	)	-RRB-
cord-260708-l9w5jhsw	178	6	,	,	,
cord-260708-l9w5jhsw	178	7	which	which	WDT
cord-260708-l9w5jhsw	178	8	,	,	,
cord-260708-l9w5jhsw	178	9	although	although	IN
cord-260708-l9w5jhsw	178	10	originally	originally	RB
cord-260708-l9w5jhsw	178	11	suggested	suggest	VBN
cord-260708-l9w5jhsw	178	12	to	to	TO
cord-260708-l9w5jhsw	178	13	be	be	VB
cord-260708-l9w5jhsw	178	14	specific	specific	JJ
cord-260708-l9w5jhsw	178	15	for	for	IN
cord-260708-l9w5jhsw	178	16	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	178	17	[	[	-LRB-
cord-260708-l9w5jhsw	178	18	8	8	CD
cord-260708-l9w5jhsw	178	19	]	]	-RRB-
cord-260708-l9w5jhsw	178	20	,	,	,
cord-260708-l9w5jhsw	178	21	appears	appear	VBZ
cord-260708-l9w5jhsw	178	22	to	to	TO
cord-260708-l9w5jhsw	178	23	be	be	VB
cord-260708-l9w5jhsw	178	24	conserved	conserve	VBN
cord-260708-l9w5jhsw	178	25	in	in	IN
cord-260708-l9w5jhsw	178	26	other	other	JJ
cord-260708-l9w5jhsw	178	27	segmented	segmented	JJ
cord-260708-l9w5jhsw	178	28	negative	negative	JJ
cord-260708-l9w5jhsw	178	29	-	-	HYPH
cord-260708-l9w5jhsw	178	30	strand	strand	NN
cord-260708-l9w5jhsw	178	31	RNA	RNA	NNP
cord-260708-l9w5jhsw	178	32	viruses	virus	NNS
cord-260708-l9w5jhsw	178	33	[	[	-LRB-
cord-260708-l9w5jhsw	178	34	94	94	CD
cord-260708-l9w5jhsw	178	35	]	]	-RRB-
cord-260708-l9w5jhsw	178	36	.	.	.
cord-260708-l9w5jhsw	179	1	Protein	protein	NN
cord-260708-l9w5jhsw	179	2	sequence	sequence	NN
cord-260708-l9w5jhsw	179	3	analysis	analysis	NN
cord-260708-l9w5jhsw	179	4	shows	show	VBZ
cord-260708-l9w5jhsw	179	5	that	that	IN
cord-260708-l9w5jhsw	179	6	the	the	DT
cord-260708-l9w5jhsw	179	7	distances	distance	NNS
cord-260708-l9w5jhsw	179	8	between	between	IN
cord-260708-l9w5jhsw	179	9	regions	region	NNS
cord-260708-l9w5jhsw	179	10	appear	appear	VBP
cord-260708-l9w5jhsw	179	11	to	to	TO
cord-260708-l9w5jhsw	179	12	be	be	VB
cord-260708-l9w5jhsw	179	13	conserved	conserve	VBN
cord-260708-l9w5jhsw	179	14	among	among	IN
cord-260708-l9w5jhsw	179	15	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	179	16	,	,	,
cord-260708-l9w5jhsw	179	17	with	with	IN
cord-260708-l9w5jhsw	179	18	the	the	DT
cord-260708-l9w5jhsw	179	19	exception	exception	NN
cord-260708-l9w5jhsw	179	20	of	of	IN
cord-260708-l9w5jhsw	179	21	the	the	DT
cord-260708-l9w5jhsw	179	22	interval	interval	NN
cord-260708-l9w5jhsw	179	23	between	between	IN
cord-260708-l9w5jhsw	179	24	regions	region	NNS
cord-260708-l9w5jhsw	179	25	2	2	CD
cord-260708-l9w5jhsw	179	26	and	and	CC
cord-260708-l9w5jhsw	179	27	3	3	CD
cord-260708-l9w5jhsw	179	28	,	,	,
cord-260708-l9w5jhsw	179	29	where	where	WRB
cord-260708-l9w5jhsw	179	30	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	179	31	appear	appear	VBP
cord-260708-l9w5jhsw	179	32	to	to	TO
cord-260708-l9w5jhsw	179	33	have	have	VB
cord-260708-l9w5jhsw	179	34	much	much	RB
cord-260708-l9w5jhsw	179	35	longer	long	JJR
cord-260708-l9w5jhsw	179	36	amino	amino	NN
cord-260708-l9w5jhsw	179	37	acid	acid	NN
cord-260708-l9w5jhsw	179	38	sequences	sequence	NNS
cord-260708-l9w5jhsw	179	39	than	than	IN
cord-260708-l9w5jhsw	179	40	other	other	JJ
cord-260708-l9w5jhsw	179	41	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	179	42	(	(	-LRB-
cord-260708-l9w5jhsw	179	43	Fig	Fig	NNP
cord-260708-l9w5jhsw	179	44	.	.	NNP
cord-260708-l9w5jhsw	179	45	4	4	CD
cord-260708-l9w5jhsw	179	46	)	)	-RRB-
cord-260708-l9w5jhsw	179	47	.	.	.
cord-260708-l9w5jhsw	180	1	Region	region	NN
cord-260708-l9w5jhsw	180	2	1	1	CD
cord-260708-l9w5jhsw	180	3	,	,	,
cord-260708-l9w5jhsw	180	4	based	base	VBN
cord-260708-l9w5jhsw	180	5	on	on	IN
cord-260708-l9w5jhsw	180	6	sequence	sequence	NN
cord-260708-l9w5jhsw	180	7	similarity	similarity	NN
cord-260708-l9w5jhsw	180	8	with	with	IN
cord-260708-l9w5jhsw	180	9	other	other	JJ
cord-260708-l9w5jhsw	180	10	viruses	virus	NNS
cord-260708-l9w5jhsw	180	11	,	,	,
cord-260708-l9w5jhsw	180	12	appears	appear	VBZ
cord-260708-l9w5jhsw	180	13	to	to	TO
cord-260708-l9w5jhsw	180	14	be	be	VB
cord-260708-l9w5jhsw	180	15	responsible	responsible	JJ
cord-260708-l9w5jhsw	180	16	for	for	IN
cord-260708-l9w5jhsw	180	17	capsnatching	capsnatche	VBG
cord-260708-l9w5jhsw	180	18	endonuclease	endonuclease	NN
cord-260708-l9w5jhsw	180	19	activity	activity	NN
cord-260708-l9w5jhsw	180	20	[	[	-LRB-
cord-260708-l9w5jhsw	180	21	52	52	CD
cord-260708-l9w5jhsw	180	22	,	,	,
cord-260708-l9w5jhsw	180	23	136	136	CD
cord-260708-l9w5jhsw	180	24	,	,	,
cord-260708-l9w5jhsw	180	25	189	189	CD
cord-260708-l9w5jhsw	180	26	]	]	-RRB-
cord-260708-l9w5jhsw	180	27	;	;	:
cord-260708-l9w5jhsw	180	28	however	however	RB
cord-260708-l9w5jhsw	180	29	,	,	,
cord-260708-l9w5jhsw	180	30	this	this	DT
cord-260708-l9w5jhsw	180	31	needs	need	VBZ
cord-260708-l9w5jhsw	180	32	to	to	TO
cord-260708-l9w5jhsw	180	33	be	be	VB
cord-260708-l9w5jhsw	180	34	confirmed	confirm	VBN
cord-260708-l9w5jhsw	180	35	experimentally	experimentally	RB
cord-260708-l9w5jhsw	180	36	.	.	.
cord-260708-l9w5jhsw	181	1	In	in	IN
cord-260708-l9w5jhsw	181	2	the	the	DT
cord-260708-l9w5jhsw	181	3	case	case	NN
cord-260708-l9w5jhsw	181	4	of	of	IN
cord-260708-l9w5jhsw	181	5	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	181	6	,	,	,
cord-260708-l9w5jhsw	181	7	the	the	DT
cord-260708-l9w5jhsw	181	8	RdRp	RdRp	NNP
cord-260708-l9w5jhsw	181	9	accounts	account	NNS
cord-260708-l9w5jhsw	181	10	for	for	IN
cord-260708-l9w5jhsw	181	11	only	only	RB
cord-260708-l9w5jhsw	181	12	one	one	CD
cord-260708-l9w5jhsw	181	13	-	-	HYPH
cord-260708-l9w5jhsw	181	14	third	third	NN
cord-260708-l9w5jhsw	181	15	of	of	IN
cord-260708-l9w5jhsw	181	16	the	the	DT
cord-260708-l9w5jhsw	181	17	entire	entire	JJ
cord-260708-l9w5jhsw	181	18	L	l	NN
cord-260708-l9w5jhsw	181	19	protein	protein	NN
cord-260708-l9w5jhsw	181	20	(	(	-LRB-
cord-260708-l9w5jhsw	181	21	Fig	Fig	NNP
cord-260708-l9w5jhsw	181	22	.	.	.
cord-260708-l9w5jhsw	181	23	4	4	CD
cord-260708-l9w5jhsw	181	24	)	)	-RRB-
cord-260708-l9w5jhsw	181	25	,	,	,
cord-260708-l9w5jhsw	181	26	with	with	IN
cord-260708-l9w5jhsw	181	27	regions	region	NNS
cord-260708-l9w5jhsw	181	28	of	of	IN
cord-260708-l9w5jhsw	181	29	unidentified	unidentified	JJ
cord-260708-l9w5jhsw	181	30	function	function	NN
cord-260708-l9w5jhsw	181	31	in	in	IN
cord-260708-l9w5jhsw	181	32	both	both	CC
cord-260708-l9w5jhsw	181	33	the	the	DT
cord-260708-l9w5jhsw	181	34	amino	amino	NNS
cord-260708-l9w5jhsw	181	35	(	(	-LRB-
cord-260708-l9w5jhsw	181	36	N	N	NNP
cord-260708-l9w5jhsw	181	37	)	)	-RRB-
cord-260708-l9w5jhsw	181	38	and	and	CC
cord-260708-l9w5jhsw	181	39	carboxy	carboxy	NNP
cord-260708-l9w5jhsw	181	40	(	(	-LRB-
cord-260708-l9w5jhsw	181	41	C	C	NNP
cord-260708-l9w5jhsw	181	42	)	)	-RRB-
cord-260708-l9w5jhsw	181	43	termini	termini	NNP
cord-260708-l9w5jhsw	181	44	[	[	-LRB-
cord-260708-l9w5jhsw	181	45	94	94	CD
cord-260708-l9w5jhsw	181	46	]	]	-RRB-
cord-260708-l9w5jhsw	181	47	.	.	.
cord-260708-l9w5jhsw	182	1	All	all	DT
cord-260708-l9w5jhsw	182	2	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	182	3	have	have	VBP
cord-260708-l9w5jhsw	182	4	a	a	DT
cord-260708-l9w5jhsw	182	5	significant	significant	JJ
cord-260708-l9w5jhsw	182	6	C	c	NN
cord-260708-l9w5jhsw	182	7	-	-	HYPH
cord-260708-l9w5jhsw	182	8	terminal	terminal	NN
cord-260708-l9w5jhsw	182	9	section	section	NN
cord-260708-l9w5jhsw	182	10	after	after	IN
cord-260708-l9w5jhsw	182	11	the	the	DT
cord-260708-l9w5jhsw	182	12	RdRp	RdRp	NNP
cord-260708-l9w5jhsw	182	13	,	,	,
cord-260708-l9w5jhsw	182	14	although	although	IN
cord-260708-l9w5jhsw	182	15	the	the	DT
cord-260708-l9w5jhsw	182	16	function	function	NN
cord-260708-l9w5jhsw	182	17	of	of	IN
cord-260708-l9w5jhsw	182	18	this	this	DT
cord-260708-l9w5jhsw	182	19	region	region	NN
cord-260708-l9w5jhsw	182	20	is	be	VBZ
cord-260708-l9w5jhsw	182	21	so	so	RB
cord-260708-l9w5jhsw	182	22	far	far	RB
cord-260708-l9w5jhsw	182	23	unknown	unknown	JJ
cord-260708-l9w5jhsw	182	24	in	in	IN
cord-260708-l9w5jhsw	182	25	any	any	DT
cord-260708-l9w5jhsw	182	26	of	of	IN
cord-260708-l9w5jhsw	182	27	the	the	DT
cord-260708-l9w5jhsw	182	28	viruses	virus	NNS
cord-260708-l9w5jhsw	182	29	of	of	IN
cord-260708-l9w5jhsw	182	30	this	this	DT
cord-260708-l9w5jhsw	182	31	family	family	NN
cord-260708-l9w5jhsw	182	32	,	,	,
cord-260708-l9w5jhsw	182	33	and	and	CC
cord-260708-l9w5jhsw	182	34	there	there	EX
cord-260708-l9w5jhsw	182	35	appear	appear	VBP
cord-260708-l9w5jhsw	182	36	to	to	TO
cord-260708-l9w5jhsw	182	37	be	be	VB
cord-260708-l9w5jhsw	182	38	no	no	DT
cord-260708-l9w5jhsw	182	39	cross	cross	NN
cord-260708-l9w5jhsw	182	40	-	-	JJ
cord-260708-l9w5jhsw	182	41	genera	genera	RB
cord-260708-l9w5jhsw	182	42	-	-	HYPH
cord-260708-l9w5jhsw	182	43	conserved	conserve	VBN
cord-260708-l9w5jhsw	182	44	motifs	motif	NNS
cord-260708-l9w5jhsw	182	45	[	[	-LRB-
cord-260708-l9w5jhsw	182	46	136	136	CD
cord-260708-l9w5jhsw	182	47	]	]	-RRB-
cord-260708-l9w5jhsw	182	48	.	.	.
cord-260708-l9w5jhsw	183	1	N	n	CD
cord-260708-l9w5jhsw	183	2	-	-	HYPH
cord-260708-l9w5jhsw	183	3	terminal	terminal	NN
cord-260708-l9w5jhsw	183	4	to	to	IN
cord-260708-l9w5jhsw	183	5	the	the	DT
cord-260708-l9w5jhsw	183	6	RdRp	RdRp	NNP
cord-260708-l9w5jhsw	183	7	motifs	motif	NNS
cord-260708-l9w5jhsw	183	8	,	,	,
cord-260708-l9w5jhsw	183	9	the	the	DT
cord-260708-l9w5jhsw	183	10	L	l	NN
cord-260708-l9w5jhsw	183	11	proteins	protein	NNS
cord-260708-l9w5jhsw	183	12	of	of	IN
cord-260708-l9w5jhsw	183	13	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	183	14	contain	contain	VBP
cord-260708-l9w5jhsw	183	15	several	several	JJ
cord-260708-l9w5jhsw	183	16	additional	additional	JJ
cord-260708-l9w5jhsw	183	17	domains	domain	NNS
cord-260708-l9w5jhsw	183	18	that	that	WDT
cord-260708-l9w5jhsw	183	19	are	be	VBP
cord-260708-l9w5jhsw	183	20	unique	unique	JJ
cord-260708-l9w5jhsw	183	21	to	to	IN
cord-260708-l9w5jhsw	183	22	this	this	DT
cord-260708-l9w5jhsw	183	23	genus	genus	NN
cord-260708-l9w5jhsw	183	24	,	,	,
cord-260708-l9w5jhsw	183	25	of	of	IN
cord-260708-l9w5jhsw	183	26	which	which	WDT
cord-260708-l9w5jhsw	183	27	the	the	DT
cord-260708-l9w5jhsw	183	28	ovarian	ovarian	JJ
cord-260708-l9w5jhsw	183	29	-	-	HYPH
cord-260708-l9w5jhsw	183	30	tumour	tumour	NN
cord-260708-l9w5jhsw	184	1	(	(	-LRB-
cord-260708-l9w5jhsw	184	2	OTU)like	otu)like	IN
cord-260708-l9w5jhsw	184	3	protease	protease	NN
cord-260708-l9w5jhsw	184	4	domain	domain	NN
cord-260708-l9w5jhsw	184	5	is	be	VBZ
cord-260708-l9w5jhsw	184	6	the	the	DT
cord-260708-l9w5jhsw	184	7	most	most	RBS
cord-260708-l9w5jhsw	184	8	studied	study	VBN
cord-260708-l9w5jhsw	184	9	[	[	-LRB-
cord-260708-l9w5jhsw	184	10	2	2	CD
cord-260708-l9w5jhsw	184	11	,	,	,
cord-260708-l9w5jhsw	184	12	29	29	CD
cord-260708-l9w5jhsw	184	13	,	,	,
cord-260708-l9w5jhsw	184	14	85	85	CD
cord-260708-l9w5jhsw	184	15	,	,	,
cord-260708-l9w5jhsw	184	16	89	89	CD
cord-260708-l9w5jhsw	184	17	,	,	,
cord-260708-l9w5jhsw	184	18	94	94	CD
cord-260708-l9w5jhsw	184	19	]	]	-RRB-
cord-260708-l9w5jhsw	184	20	.	.	.
cord-260708-l9w5jhsw	185	1	This	this	DT
cord-260708-l9w5jhsw	185	2	domain	domain	NN
cord-260708-l9w5jhsw	185	3	belongs	belong	VBZ
cord-260708-l9w5jhsw	185	4	to	to	IN
cord-260708-l9w5jhsw	185	5	a	a	DT
cord-260708-l9w5jhsw	185	6	larger	large	JJR
cord-260708-l9w5jhsw	185	7	papain	papain	NN
cord-260708-l9w5jhsw	185	8	-	-	HYPH
cord-260708-l9w5jhsw	185	9	like	like	JJ
cord-260708-l9w5jhsw	185	10	cysteine	cysteine	NN
cord-260708-l9w5jhsw	185	11	protease	protease	NN
cord-260708-l9w5jhsw	185	12	family	family	NN
cord-260708-l9w5jhsw	185	13	also	also	RB
cord-260708-l9w5jhsw	185	14	found	find	VBD
cord-260708-l9w5jhsw	185	15	in	in	IN
cord-260708-l9w5jhsw	185	16	other	other	JJ
cord-260708-l9w5jhsw	185	17	viruses	virus	NNS
cord-260708-l9w5jhsw	185	18	(	(	-LRB-
cord-260708-l9w5jhsw	185	19	e.g.	e.g.	RB
cord-260708-l9w5jhsw	185	20	,	,	,
cord-260708-l9w5jhsw	185	21	blueberry	blueberry	NN
cord-260708-l9w5jhsw	185	22	scorch	scorch	VBP
cord-260708-l9w5jhsw	185	23	virus	virus	NN
cord-260708-l9w5jhsw	185	24	(	(	-LRB-
cord-260708-l9w5jhsw	185	25	BlScV	BlScV	NNP
cord-260708-l9w5jhsw	185	26	)	)	-RRB-
cord-260708-l9w5jhsw	185	27	of	of	IN
cord-260708-l9w5jhsw	185	28	the	the	DT
cord-260708-l9w5jhsw	185	29	genus	genus	JJ
cord-260708-l9w5jhsw	185	30	Carlavirus	Carlavirus	NNP
cord-260708-l9w5jhsw	185	31	,	,	,
cord-260708-l9w5jhsw	185	32	and	and	CC
cord-260708-l9w5jhsw	185	33	equine	equine	JJ
cord-260708-l9w5jhsw	185	34	arteritis	arteritis	NN
cord-260708-l9w5jhsw	185	35	virus	virus	NN
cord-260708-l9w5jhsw	185	36	(	(	-LRB-
cord-260708-l9w5jhsw	185	37	EAV	EAV	NNP
cord-260708-l9w5jhsw	185	38	)	)	-RRB-
cord-260708-l9w5jhsw	185	39	and	and	CC
cord-260708-l9w5jhsw	185	40	porcine	porcine	JJ
cord-260708-l9w5jhsw	185	41	respiratory	respiratory	JJ
cord-260708-l9w5jhsw	185	42	and	and	CC
cord-260708-l9w5jhsw	185	43	reproductive	reproductive	JJ
cord-260708-l9w5jhsw	185	44	syndrome	syndrome	NN
cord-260708-l9w5jhsw	185	45	virus	virus	NN
cord-260708-l9w5jhsw	185	46	(	(	-LRB-
cord-260708-l9w5jhsw	185	47	PRRSV	PRRSV	NNP
cord-260708-l9w5jhsw	185	48	)	)	-RRB-
cord-260708-l9w5jhsw	185	49	of	of	IN
cord-260708-l9w5jhsw	185	50	the	the	DT
cord-260708-l9w5jhsw	185	51	genus	genus	NN
cord-260708-l9w5jhsw	185	52	Arterivirus	Arterivirus	NNP
cord-260708-l9w5jhsw	185	53	)	)	-RRB-
cord-260708-l9w5jhsw	185	54	,	,	,
cord-260708-l9w5jhsw	185	55	in	in	IN
cord-260708-l9w5jhsw	185	56	Saccharomyces	Saccharomyces	NNP
cord-260708-l9w5jhsw	185	57	cerevisiae	cerevisiae	NNS
cord-260708-l9w5jhsw	185	58	,	,	,
cord-260708-l9w5jhsw	185	59	in	in	IN
cord-260708-l9w5jhsw	185	60	Drosophila	Drosophila	NNP
cord-260708-l9w5jhsw	185	61	melanogaster	melanogaster	NN
cord-260708-l9w5jhsw	185	62	and	and	CC
cord-260708-l9w5jhsw	185	63	in	in	IN
cord-260708-l9w5jhsw	185	64	mammalian	mammalian	JJ
cord-260708-l9w5jhsw	185	65	cells	cell	NNS
cord-260708-l9w5jhsw	185	66	[	[	-LRB-
cord-260708-l9w5jhsw	185	67	11	11	CD
cord-260708-l9w5jhsw	185	68	,	,	,
cord-260708-l9w5jhsw	185	69	103	103	CD
cord-260708-l9w5jhsw	185	70	]	]	-RRB-
cord-260708-l9w5jhsw	185	71	.	.	.
cord-260708-l9w5jhsw	186	1	Curiously	curiously	RB
cord-260708-l9w5jhsw	186	2	,	,	,
cord-260708-l9w5jhsw	186	3	the	the	DT
cord-260708-l9w5jhsw	186	4	region	region	NN
cord-260708-l9w5jhsw	186	5	containing	contain	VBG
cord-260708-l9w5jhsw	186	6	the	the	DT
cord-260708-l9w5jhsw	186	7	OTU	OTU	NNP
cord-260708-l9w5jhsw	186	8	domain	domain	NN
cord-260708-l9w5jhsw	186	9	also	also	RB
cord-260708-l9w5jhsw	186	10	contains	contain	VBZ
cord-260708-l9w5jhsw	186	11	a	a	DT
cord-260708-l9w5jhsw	186	12	sequence	sequence	NN
cord-260708-l9w5jhsw	186	13	resembling	resemble	VBG
cord-260708-l9w5jhsw	186	14	a	a	DT
cord-260708-l9w5jhsw	186	15	topoisomerase	topoisomerase	NN
cord-260708-l9w5jhsw	186	16	-	-	HYPH
cord-260708-l9w5jhsw	186	17	like	like	JJ
cord-260708-l9w5jhsw	186	18	domain	domain	NN
cord-260708-l9w5jhsw	186	19	,	,	,
cord-260708-l9w5jhsw	186	20	located	locate	VBN
cord-260708-l9w5jhsw	186	21	at	at	IN
cord-260708-l9w5jhsw	186	22	amino	amino	NN
cord-260708-l9w5jhsw	186	23	acids	acid	NNS
cord-260708-l9w5jhsw	186	24	,	,	,
cord-260708-l9w5jhsw	186	25	and	and	CC
cord-260708-l9w5jhsw	186	26	therefore	therefore	RB
cord-260708-l9w5jhsw	186	27	lying	lie	VBG
cord-260708-l9w5jhsw	186	28	between	between	IN
cord-260708-l9w5jhsw	186	29	amino	amino	JJ
cord-260708-l9w5jhsw	186	30	acids	acid	NNS
cord-260708-l9w5jhsw	186	31	that	that	WDT
cord-260708-l9w5jhsw	186	32	form	form	VBP
cord-260708-l9w5jhsw	186	33	part	part	NN
cord-260708-l9w5jhsw	186	34	of	of	IN
cord-260708-l9w5jhsw	186	35	the	the	DT
cord-260708-l9w5jhsw	186	36	of	of	IN
cord-260708-l9w5jhsw	186	37	the	the	DT
cord-260708-l9w5jhsw	186	38	OTU	OTU	NNP
cord-260708-l9w5jhsw	186	39	catalytic	catalytic	JJ
cord-260708-l9w5jhsw	186	40	site	site	NN
cord-260708-l9w5jhsw	186	41	-cysteine	-cysteine	SYM
cord-260708-l9w5jhsw	186	42	40	40	CD
cord-260708-l9w5jhsw	186	43	and	and	CC
cord-260708-l9w5jhsw	186	44	histidine	histidine	NN
cord-260708-l9w5jhsw	186	45	151	151	CD
cord-260708-l9w5jhsw	186	46	[	[	-LRB-
cord-260708-l9w5jhsw	186	47	85	85	CD
cord-260708-l9w5jhsw	186	48	,	,	,
cord-260708-l9w5jhsw	186	49	94	94	CD
cord-260708-l9w5jhsw	186	50	]	]	-RRB-
cord-260708-l9w5jhsw	186	51	.	.	.
cord-260708-l9w5jhsw	187	1	The	the	DT
cord-260708-l9w5jhsw	187	2	consensus	consensus	NN
cord-260708-l9w5jhsw	187	3	topoisomerase	topoisomerase	NN
cord-260708-l9w5jhsw	187	4	motif	motif	NN
cord-260708-l9w5jhsw	188	1	The	the	DT
cord-260708-l9w5jhsw	188	2	approximate	approximate	JJ
cord-260708-l9w5jhsw	188	3	size	size	NN
cord-260708-l9w5jhsw	188	4	,	,	,
cord-260708-l9w5jhsw	188	5	expressed	express	VBN
cord-260708-l9w5jhsw	188	6	as	as	IN
cord-260708-l9w5jhsw	188	7	the	the	DT
cord-260708-l9w5jhsw	188	8	number	number	NN
cord-260708-l9w5jhsw	188	9	of	of	IN
cord-260708-l9w5jhsw	188	10	amino	amino	JJ
cord-260708-l9w5jhsw	188	11	acids	acid	NNS
cord-260708-l9w5jhsw	188	12	(	(	-LRB-
cord-260708-l9w5jhsw	188	13	aa	aa	NNP
cord-260708-l9w5jhsw	188	14	)	)	-RRB-
cord-260708-l9w5jhsw	188	15	,	,	,
cord-260708-l9w5jhsw	188	16	is	be	VBZ
cord-260708-l9w5jhsw	188	17	indicated	indicate	VBN
cord-260708-l9w5jhsw	188	18	for	for	IN
cord-260708-l9w5jhsw	188	19	each	each	DT
cord-260708-l9w5jhsw	188	20	protein	protein	NN
cord-260708-l9w5jhsw	188	21	,	,	,
cord-260708-l9w5jhsw	188	22	and	and	CC
cord-260708-l9w5jhsw	188	23	the	the	DT
cord-260708-l9w5jhsw	188	24	diagram	diagram	NN
cord-260708-l9w5jhsw	188	25	is	be	VBZ
cord-260708-l9w5jhsw	188	26	drawn	draw	VBN
cord-260708-l9w5jhsw	188	27	approximately	approximately	RB
cord-260708-l9w5jhsw	188	28	to	to	TO
cord-260708-l9w5jhsw	188	29	scale	scale	VB
cord-260708-l9w5jhsw	188	30	.	.	.
cord-260708-l9w5jhsw	189	1	See	see	VB
cord-260708-l9w5jhsw	189	2	text	text	NN
cord-260708-l9w5jhsw	189	3	for	for	IN
cord-260708-l9w5jhsw	189	4	details	detail	NNS
cord-260708-l9w5jhsw	189	5	of	of	IN
cord-260708-l9w5jhsw	189	6	the	the	DT
cord-260708-l9w5jhsw	189	7	various	various	JJ
cord-260708-l9w5jhsw	189	8	motifs	motif	NNS
cord-260708-l9w5jhsw	189	9	.	.	.
cord-260708-l9w5jhsw	190	1	Adapted	adapt	VBN
cord-260708-l9w5jhsw	190	2	from	from	IN
cord-260708-l9w5jhsw	190	3	ref	ref	NN
cord-260708-l9w5jhsw	190	4	.	.	.
cord-260708-l9w5jhsw	191	1	[	[	-LRB-
cord-260708-l9w5jhsw	191	2	91	91	CD
cord-260708-l9w5jhsw	191	3	]	]	-RRB-
cord-260708-l9w5jhsw	192	1	(	(	-LRB-
cord-260708-l9w5jhsw	192	2	SKXXY	SKXXY	NNP
cord-260708-l9w5jhsw	192	3	)	)	-RRB-
cord-260708-l9w5jhsw	192	4	is	be	VBZ
cord-260708-l9w5jhsw	192	5	not	not	RB
cord-260708-l9w5jhsw	192	6	conserved	conserve	VBN
cord-260708-l9w5jhsw	192	7	across	across	IN
cord-260708-l9w5jhsw	192	8	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	192	9	,	,	,
cord-260708-l9w5jhsw	192	10	being	be	VBG
cord-260708-l9w5jhsw	192	11	mostly	mostly	RB
cord-260708-l9w5jhsw	192	12	SLXXY	SLXXY	NNP
cord-260708-l9w5jhsw	192	13	in	in	IN
cord-260708-l9w5jhsw	192	14	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	192	15	and	and	CC
cord-260708-l9w5jhsw	192	16	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	192	17	/	/	SYM
cord-260708-l9w5jhsw	192	18	GV	GV	NNP
cord-260708-l9w5jhsw	192	19	,	,	,
cord-260708-l9w5jhsw	192	20	but	but	CC
cord-260708-l9w5jhsw	192	21	the	the	DT
cord-260708-l9w5jhsw	192	22	activesite	activesite	JJ
cord-260708-l9w5jhsw	192	23	tyrosine	tyrosine	NN
cord-260708-l9w5jhsw	192	24	is	be	VBZ
cord-260708-l9w5jhsw	192	25	conserved	conserve	VBN
cord-260708-l9w5jhsw	192	26	across	across	IN
cord-260708-l9w5jhsw	192	27	all	all	DT
cord-260708-l9w5jhsw	192	28	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	192	29	so	so	RB
cord-260708-l9w5jhsw	192	30	far	far	RB
cord-260708-l9w5jhsw	192	31	sequenced	sequence	VBN
cord-260708-l9w5jhsw	192	32	.	.	.
cord-260708-l9w5jhsw	193	1	Given	give	VBN
cord-260708-l9w5jhsw	193	2	the	the	DT
cord-260708-l9w5jhsw	193	3	structural	structural	JJ
cord-260708-l9w5jhsw	193	4	similarities	similarity	NNS
cord-260708-l9w5jhsw	193	5	between	between	IN
cord-260708-l9w5jhsw	193	6	topoisomerases	topoisomerase	NNS
cord-260708-l9w5jhsw	193	7	and	and	CC
cord-260708-l9w5jhsw	193	8	strand	strand	NN
cord-260708-l9w5jhsw	193	9	-	-	HYPH
cord-260708-l9w5jhsw	193	10	specific	specific	JJ
cord-260708-l9w5jhsw	193	11	recombinases	recombinase	NNS
cord-260708-l9w5jhsw	193	12	[	[	-LRB-
cord-260708-l9w5jhsw	193	13	35	35	CD
cord-260708-l9w5jhsw	193	14	]	]	-RRB-
cord-260708-l9w5jhsw	193	15	,	,	,
cord-260708-l9w5jhsw	193	16	this	this	DT
cord-260708-l9w5jhsw	193	17	motif	motif	NN
cord-260708-l9w5jhsw	193	18	may	may	MD
cord-260708-l9w5jhsw	193	19	indicate	indicate	VB
cord-260708-l9w5jhsw	193	20	a	a	DT
cord-260708-l9w5jhsw	193	21	role	role	NN
cord-260708-l9w5jhsw	193	22	for	for	IN
cord-260708-l9w5jhsw	193	23	this	this	DT
cord-260708-l9w5jhsw	193	24	region	region	NN
cord-260708-l9w5jhsw	193	25	of	of	IN
cord-260708-l9w5jhsw	193	26	L	L	NNP
cord-260708-l9w5jhsw	193	27	in	in	IN
cord-260708-l9w5jhsw	193	28	RNA	RNA	NNP
cord-260708-l9w5jhsw	193	29	strand	strand	NN
cord-260708-l9w5jhsw	193	30	manipulation	manipulation	NN
cord-260708-l9w5jhsw	193	31	as	as	RB
cord-260708-l9w5jhsw	193	32	well	well	RB
cord-260708-l9w5jhsw	193	33	as	as	IN
cord-260708-l9w5jhsw	193	34	its	-PRON-	PRP$
cord-260708-l9w5jhsw	193	35	function	function	NN
cord-260708-l9w5jhsw	193	36	as	as	IN
cord-260708-l9w5jhsw	193	37	a	a	DT
cord-260708-l9w5jhsw	193	38	protease	protease	NN
cord-260708-l9w5jhsw	193	39	.	.	.
cord-260708-l9w5jhsw	194	1	Alternatively	alternatively	RB
cord-260708-l9w5jhsw	194	2	,	,	,
cord-260708-l9w5jhsw	194	3	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	194	4	L	L	NNP
cord-260708-l9w5jhsw	194	5	proteins	protein	NNS
cord-260708-l9w5jhsw	194	6	may	may	MD
cord-260708-l9w5jhsw	194	7	include	include	VB
cord-260708-l9w5jhsw	194	8	their	-PRON-	PRP$
cord-260708-l9w5jhsw	194	9	own	own	JJ
cord-260708-l9w5jhsw	194	10	topoisomerase	topoisomerase	NN
cord-260708-l9w5jhsw	194	11	activity	activity	NN
cord-260708-l9w5jhsw	194	12	,	,	,
cord-260708-l9w5jhsw	194	13	rather	rather	RB
cord-260708-l9w5jhsw	194	14	than	than	IN
cord-260708-l9w5jhsw	194	15	having	have	VBG
cord-260708-l9w5jhsw	194	16	to	to	TO
cord-260708-l9w5jhsw	194	17	recruit	recruit	VB
cord-260708-l9w5jhsw	194	18	the	the	DT
cord-260708-l9w5jhsw	194	19	host	host	NN
cord-260708-l9w5jhsw	194	20	-	-	HYPH
cord-260708-l9w5jhsw	194	21	cell	cell	NN
cord-260708-l9w5jhsw	195	1	topoisomerase	topoisomerase	NNP
cord-260708-l9w5jhsw	196	1	I	-PRON-	PRP
cord-260708-l9w5jhsw	196	2	,	,	,
cord-260708-l9w5jhsw	196	3	as	as	IN
cord-260708-l9w5jhsw	196	4	has	have	VBZ
cord-260708-l9w5jhsw	196	5	been	be	VBN
cord-260708-l9w5jhsw	196	6	shown	show	VBN
cord-260708-l9w5jhsw	196	7	for	for	IN
cord-260708-l9w5jhsw	196	8	at	at	RB
cord-260708-l9w5jhsw	196	9	least	least	RBS
cord-260708-l9w5jhsw	196	10	one	one	CD
cord-260708-l9w5jhsw	196	11	non	non	JJ
cord-260708-l9w5jhsw	196	12	-	-	JJ
cord-260708-l9w5jhsw	196	13	segmented	segmented	JJ
cord-260708-l9w5jhsw	196	14	RNA	RNA	NNP
cord-260708-l9w5jhsw	196	15	virus	virus	NN
cord-260708-l9w5jhsw	196	16	[	[	-LRB-
cord-260708-l9w5jhsw	196	17	159	159	CD
cord-260708-l9w5jhsw	196	18	]	]	-RRB-
cord-260708-l9w5jhsw	196	19	.	.	.
cord-260708-l9w5jhsw	197	1	Downstream	downstream	IN
cord-260708-l9w5jhsw	197	2	of	of	IN
cord-260708-l9w5jhsw	197	3	the	the	DT
cord-260708-l9w5jhsw	197	4	OTU	OTU	NNP
cord-260708-l9w5jhsw	197	5	domain	domain	NN
cord-260708-l9w5jhsw	197	6	,	,	,
cord-260708-l9w5jhsw	197	7	the	the	DT
cord-260708-l9w5jhsw	197	8	L	L	NNP
cord-260708-l9w5jhsw	197	9	protein	protein	NN
cord-260708-l9w5jhsw	197	10	of	of	IN
cord-260708-l9w5jhsw	197	11	nairoviruses	nairoviruses	NNP
cord-260708-l9w5jhsw	197	12	contains	contain	VBZ
cord-260708-l9w5jhsw	197	13	a	a	DT
cord-260708-l9w5jhsw	197	14	C2H2-type	C2H2-type	NNP
cord-260708-l9w5jhsw	197	15	zinc	zinc	NN
cord-260708-l9w5jhsw	197	16	finger	finger	NN
cord-260708-l9w5jhsw	197	17	domain	domain	NN
cord-260708-l9w5jhsw	197	18	and	and	CC
cord-260708-l9w5jhsw	197	19	a	a	DT
cord-260708-l9w5jhsw	197	20	leucine	leucine	NN
cord-260708-l9w5jhsw	197	21	zipper	zipper	NN
cord-260708-l9w5jhsw	197	22	motif	motif	NN
cord-260708-l9w5jhsw	197	23	[	[	-LRB-
cord-260708-l9w5jhsw	197	24	85	85	CD
cord-260708-l9w5jhsw	197	25	,	,	,
cord-260708-l9w5jhsw	197	26	94	94	CD
cord-260708-l9w5jhsw	197	27	]	]	-RRB-
cord-260708-l9w5jhsw	197	28	,	,	,
cord-260708-l9w5jhsw	197	29	both	both	DT
cord-260708-l9w5jhsw	197	30	of	of	IN
cord-260708-l9w5jhsw	197	31	which	which	WDT
cord-260708-l9w5jhsw	197	32	are	be	VBP
cord-260708-l9w5jhsw	197	33	highly	highly	RB
cord-260708-l9w5jhsw	197	34	conserved	conserve	VBN
cord-260708-l9w5jhsw	197	35	among	among	IN
cord-260708-l9w5jhsw	197	36	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	197	37	,	,	,
cord-260708-l9w5jhsw	197	38	but	but	CC
cord-260708-l9w5jhsw	197	39	the	the	DT
cord-260708-l9w5jhsw	197	40	function	function	NN
cord-260708-l9w5jhsw	197	41	of	of	IN
cord-260708-l9w5jhsw	197	42	which	which	WDT
cord-260708-l9w5jhsw	197	43	in	in	IN
cord-260708-l9w5jhsw	197	44	the	the	DT
cord-260708-l9w5jhsw	197	45	viral	viral	JJ
cord-260708-l9w5jhsw	197	46	replication	replication	NN
cord-260708-l9w5jhsw	197	47	cycle	cycle	NN
cord-260708-l9w5jhsw	197	48	is	be	VBZ
cord-260708-l9w5jhsw	197	49	still	still	RB
cord-260708-l9w5jhsw	197	50	to	to	TO
cord-260708-l9w5jhsw	197	51	be	be	VB
cord-260708-l9w5jhsw	197	52	determined	determine	VBN
cord-260708-l9w5jhsw	197	53	.	.	.
cord-260708-l9w5jhsw	198	1	Interestingly	interestingly	RB
cord-260708-l9w5jhsw	198	2	,	,	,
cord-260708-l9w5jhsw	198	3	the	the	DT
cord-260708-l9w5jhsw	198	4	zinc	zinc	NN
cord-260708-l9w5jhsw	198	5	-	-	HYPH
cord-260708-l9w5jhsw	198	6	finger	finger	NN
cord-260708-l9w5jhsw	198	7	domain	domain	NN
cord-260708-l9w5jhsw	198	8	and	and	CC
cord-260708-l9w5jhsw	198	9	leucine	leucine	NN
cord-260708-l9w5jhsw	198	10	zipper	zipper	NN
cord-260708-l9w5jhsw	198	11	motif	motif	NN
cord-260708-l9w5jhsw	198	12	are	be	VBP
cord-260708-l9w5jhsw	198	13	located	locate	VBN
cord-260708-l9w5jhsw	198	14	in	in	IN
cord-260708-l9w5jhsw	198	15	region	region	NN
cord-260708-l9w5jhsw	198	16	1	1	CD
cord-260708-l9w5jhsw	198	17	and	and	CC
cord-260708-l9w5jhsw	198	18	region	region	NN
cord-260708-l9w5jhsw	198	19	2	2	CD
cord-260708-l9w5jhsw	198	20	,	,	,
cord-260708-l9w5jhsw	198	21	respectively	respectively	RB
cord-260708-l9w5jhsw	198	22	,	,	,
cord-260708-l9w5jhsw	198	23	of	of	IN
cord-260708-l9w5jhsw	198	24	the	the	DT
cord-260708-l9w5jhsw	198	25	nairoviral	nairoviral	NNP
cord-260708-l9w5jhsw	198	26	L	L	NNP
cord-260708-l9w5jhsw	198	27	proteins	protein	NNS
cord-260708-l9w5jhsw	198	28	but	but	CC
cord-260708-l9w5jhsw	198	29	do	do	VBP
cord-260708-l9w5jhsw	198	30	not	not	RB
cord-260708-l9w5jhsw	198	31	appear	appear	VB
cord-260708-l9w5jhsw	198	32	to	to	TO
cord-260708-l9w5jhsw	198	33	be	be	VB
cord-260708-l9w5jhsw	198	34	present	present	JJ
cord-260708-l9w5jhsw	198	35	in	in	IN
cord-260708-l9w5jhsw	198	36	these	these	DT
cord-260708-l9w5jhsw	198	37	regions	region	NNS
cord-260708-l9w5jhsw	198	38	in	in	IN
cord-260708-l9w5jhsw	198	39	the	the	DT
cord-260708-l9w5jhsw	198	40	L	l	NN
cord-260708-l9w5jhsw	198	41	proteins	protein	NNS
cord-260708-l9w5jhsw	198	42	of	of	IN
cord-260708-l9w5jhsw	198	43	other	other	JJ
cord-260708-l9w5jhsw	198	44	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	198	45	.	.	.
cord-260708-l9w5jhsw	199	1	The	the	DT
cord-260708-l9w5jhsw	199	2	OTU	otu	NN
cord-260708-l9w5jhsw	199	3	-	-	HYPH
cord-260708-l9w5jhsw	199	4	domain	domain	NN
cord-260708-l9w5jhsw	199	5	protease	protease	NN
cord-260708-l9w5jhsw	199	6	activity	activity	NN
cord-260708-l9w5jhsw	199	7	is	be	VBZ
cord-260708-l9w5jhsw	199	8	dispensable	dispensable	JJ
cord-260708-l9w5jhsw	199	9	for	for	IN
cord-260708-l9w5jhsw	199	10	virus	virus	NN
cord-260708-l9w5jhsw	199	11	genome	genome	NN
cord-260708-l9w5jhsw	199	12	replication	replication	NN
cord-260708-l9w5jhsw	199	13	[	[	-LRB-
cord-260708-l9w5jhsw	199	14	16	16	CD
cord-260708-l9w5jhsw	199	15	]	]	-RRB-
cord-260708-l9w5jhsw	199	16	,	,	,
cord-260708-l9w5jhsw	199	17	and	and	CC
cord-260708-l9w5jhsw	199	18	most	most	JJS
cord-260708-l9w5jhsw	199	19	recent	recent	JJ
cord-260708-l9w5jhsw	199	20	studies	study	NNS
cord-260708-l9w5jhsw	199	21	have	have	VBP
cord-260708-l9w5jhsw	199	22	focussed	focusse	VBN
cord-260708-l9w5jhsw	199	23	on	on	IN
cord-260708-l9w5jhsw	199	24	the	the	DT
cord-260708-l9w5jhsw	199	25	effects	effect	NNS
cord-260708-l9w5jhsw	199	26	of	of	IN
cord-260708-l9w5jhsw	199	27	this	this	DT
cord-260708-l9w5jhsw	199	28	enzymatic	enzymatic	JJ
cord-260708-l9w5jhsw	199	29	activity	activity	NN
cord-260708-l9w5jhsw	199	30	on	on	IN
cord-260708-l9w5jhsw	199	31	host	host	NN
cord-260708-l9w5jhsw	199	32	proteins	protein	NNS
cord-260708-l9w5jhsw	199	33	.	.	.
cord-260708-l9w5jhsw	200	1	Mammalian	mammalian	JJ
cord-260708-l9w5jhsw	200	2	OTU	otu	NN
cord-260708-l9w5jhsw	200	3	-	-	HYPH
cord-260708-l9w5jhsw	200	4	domain	domain	NN
cord-260708-l9w5jhsw	200	5	proteins	protein	NNS
cord-260708-l9w5jhsw	200	6	are	be	VBP
cord-260708-l9w5jhsw	200	7	primarily	primarily	RB
cord-260708-l9w5jhsw	200	8	deubiquitinating	deubiquitinate	VBG
cord-260708-l9w5jhsw	200	9	enzymes	enzyme	NNS
cord-260708-l9w5jhsw	200	10	(	(	-LRB-
cord-260708-l9w5jhsw	200	11	DUBs	dub	NNS
cord-260708-l9w5jhsw	200	12	)	)	-RRB-
cord-260708-l9w5jhsw	200	13	,	,	,
cord-260708-l9w5jhsw	200	14	responsible	responsible	JJ
cord-260708-l9w5jhsw	200	15	for	for	IN
cord-260708-l9w5jhsw	200	16	cleaving	cleave	VBG
cord-260708-l9w5jhsw	200	17	the	the	DT
cord-260708-l9w5jhsw	200	18	modified	modify	VBN
cord-260708-l9w5jhsw	200	19	peptide	peptide	NN
cord-260708-l9w5jhsw	200	20	bond	bond	NN
cord-260708-l9w5jhsw	200	21	that	that	WDT
cord-260708-l9w5jhsw	200	22	links	link	VBZ
cord-260708-l9w5jhsw	200	23	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	200	24	(	(	-LRB-
cord-260708-l9w5jhsw	200	25	Ub	Ub	NNP
cord-260708-l9w5jhsw	200	26	)	)	-RRB-
cord-260708-l9w5jhsw	200	27	to	to	IN
cord-260708-l9w5jhsw	200	28	hostcell	hostcell	NNP
cord-260708-l9w5jhsw	200	29	proteins	protein	NNS
cord-260708-l9w5jhsw	200	30	or	or	CC
cord-260708-l9w5jhsw	200	31	to	to	IN
cord-260708-l9w5jhsw	200	32	other	other	JJ
cord-260708-l9w5jhsw	200	33	Ub	ub	JJ
cord-260708-l9w5jhsw	200	34	molecules	molecule	NNS
cord-260708-l9w5jhsw	200	35	.	.	.
cord-260708-l9w5jhsw	201	1	Most	Most	JJS
cord-260708-l9w5jhsw	201	2	mammalian	mammalian	JJ
cord-260708-l9w5jhsw	201	3	DUBs	dub	NNS
cord-260708-l9w5jhsw	201	4	are	be	VBP
cord-260708-l9w5jhsw	201	5	only	only	RB
cord-260708-l9w5jhsw	201	6	able	able	JJ
cord-260708-l9w5jhsw	201	7	to	to	TO
cord-260708-l9w5jhsw	201	8	deubiquitinate	deubiquitinate	VB
cord-260708-l9w5jhsw	201	9	and	and	CC
cord-260708-l9w5jhsw	201	10	usually	usually	RB
cord-260708-l9w5jhsw	201	11	have	have	VBP
cord-260708-l9w5jhsw	201	12	a	a	DT
cord-260708-l9w5jhsw	201	13	limited	limited	JJ
cord-260708-l9w5jhsw	201	14	set	set	NN
cord-260708-l9w5jhsw	201	15	of	of	IN
cord-260708-l9w5jhsw	201	16	targets	target	NNS
cord-260708-l9w5jhsw	201	17	that	that	WDT
cord-260708-l9w5jhsw	201	18	they	-PRON-	PRP
cord-260708-l9w5jhsw	201	19	de	de	VBP
cord-260708-l9w5jhsw	201	20	-	-	NN
cord-260708-l9w5jhsw	201	21	conjugate	conjugate	NNP
cord-260708-l9w5jhsw	201	22	in	in	IN
cord-260708-l9w5jhsw	201	23	this	this	DT
cord-260708-l9w5jhsw	201	24	way	way	NN
cord-260708-l9w5jhsw	201	25	(	(	-LRB-
cord-260708-l9w5jhsw	201	26	reviewed	review	VBN
cord-260708-l9w5jhsw	201	27	in	in	IN
cord-260708-l9w5jhsw	201	28	ref	ref	NN
cord-260708-l9w5jhsw	201	29	.	.	.
cord-260708-l9w5jhsw	202	1	[	[	-LRB-
cord-260708-l9w5jhsw	202	2	96	96	CD
cord-260708-l9w5jhsw	202	3	]	]	-RRB-
cord-260708-l9w5jhsw	202	4	)	)	-RRB-
cord-260708-l9w5jhsw	202	5	.	.	.
cord-260708-l9w5jhsw	203	1	The	the	DT
cord-260708-l9w5jhsw	203	2	OTU	OTU	NNP
cord-260708-l9w5jhsw	203	3	domains	domain	NNS
cord-260708-l9w5jhsw	203	4	of	of	IN
cord-260708-l9w5jhsw	203	5	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	203	6	,	,	,
cord-260708-l9w5jhsw	203	7	in	in	IN
cord-260708-l9w5jhsw	203	8	contrast	contrast	NN
cord-260708-l9w5jhsw	203	9	,	,	,
cord-260708-l9w5jhsw	203	10	are	be	VBP
cord-260708-l9w5jhsw	203	11	capable	capable	JJ
cord-260708-l9w5jhsw	203	12	of	of	IN
cord-260708-l9w5jhsw	203	13	de	de	NN
cord-260708-l9w5jhsw	203	14	-	-	NN
cord-260708-l9w5jhsw	203	15	conjugating	conjugate	VBG
cord-260708-l9w5jhsw	203	16	not	not	RB
cord-260708-l9w5jhsw	203	17	only	only	RB
cord-260708-l9w5jhsw	203	18	Ub	Ub	NNP
cord-260708-l9w5jhsw	203	19	but	but	CC
cord-260708-l9w5jhsw	203	20	also	also	RB
cord-260708-l9w5jhsw	203	21	other	other	JJ
cord-260708-l9w5jhsw	203	22	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	203	23	-	-	HYPH
cord-260708-l9w5jhsw	203	24	like	like	JJ
cord-260708-l9w5jhsw	203	25	peptides	peptide	NNS
cord-260708-l9w5jhsw	203	26	,	,	,
cord-260708-l9w5jhsw	203	27	notably	notably	RB
cord-260708-l9w5jhsw	203	28	the	the	DT
cord-260708-l9w5jhsw	203	29	interferonstimulated	interferonstimulate	VBN
cord-260708-l9w5jhsw	203	30	gene	gene	NN
cord-260708-l9w5jhsw	203	31	15	15	CD
cord-260708-l9w5jhsw	203	32	protein	protein	NN
cord-260708-l9w5jhsw	203	33	(	(	-LRB-
cord-260708-l9w5jhsw	203	34	ISG15	ISG15	NNP
cord-260708-l9w5jhsw	203	35	)	)	-RRB-
cord-260708-l9w5jhsw	203	36	,	,	,
cord-260708-l9w5jhsw	203	37	removing	remove	VBG
cord-260708-l9w5jhsw	203	38	these	these	DT
cord-260708-l9w5jhsw	203	39	peptides	peptide	NNS
cord-260708-l9w5jhsw	203	40	from	from	IN
cord-260708-l9w5jhsw	203	41	a	a	DT
cord-260708-l9w5jhsw	203	42	variety	variety	NN
cord-260708-l9w5jhsw	203	43	of	of	IN
cord-260708-l9w5jhsw	203	44	protein	protein	NN
cord-260708-l9w5jhsw	203	45	targets	target	NNS
cord-260708-l9w5jhsw	203	46	[	[	-LRB-
cord-260708-l9w5jhsw	203	47	10	10	CD
cord-260708-l9w5jhsw	203	48	,	,	,
cord-260708-l9w5jhsw	203	49	69	69	CD
cord-260708-l9w5jhsw	203	50	,	,	,
cord-260708-l9w5jhsw	203	51	84	84	CD
cord-260708-l9w5jhsw	203	52	]	]	-RRB-
cord-260708-l9w5jhsw	203	53	.	.	.
cord-260708-l9w5jhsw	204	1	It	-PRON-	PRP
cord-260708-l9w5jhsw	204	2	has	have	VBZ
cord-260708-l9w5jhsw	204	3	been	be	VBN
cord-260708-l9w5jhsw	204	4	shown	show	VBN
cord-260708-l9w5jhsw	204	5	that	that	IN
cord-260708-l9w5jhsw	204	6	amino	amino	JJ
cord-260708-l9w5jhsw	204	7	acids	acid	NNS
cord-260708-l9w5jhsw	204	8	1	1	CD
cord-260708-l9w5jhsw	204	9	to	to	IN
cord-260708-l9w5jhsw	204	10	169	169	CD
cord-260708-l9w5jhsw	204	11	of	of	IN
cord-260708-l9w5jhsw	204	12	the	the	DT
cord-260708-l9w5jhsw	204	13	L	l	NN
cord-260708-l9w5jhsw	204	14	proteins	protein	NNS
cord-260708-l9w5jhsw	204	15	of	of	IN
cord-260708-l9w5jhsw	204	16	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	204	17	,	,	,
cord-260708-l9w5jhsw	204	18	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	204	19	or	or	CC
cord-260708-l9w5jhsw	204	20	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	204	21	are	be	VBP
cord-260708-l9w5jhsw	204	22	sufficient	sufficient	JJ
cord-260708-l9w5jhsw	204	23	for	for	IN
cord-260708-l9w5jhsw	204	24	enzymatic	enzymatic	JJ
cord-260708-l9w5jhsw	204	25	activity	activity	NN
cord-260708-l9w5jhsw	204	26	,	,	,
cord-260708-l9w5jhsw	204	27	and	and	CC
cord-260708-l9w5jhsw	204	28	conserved	conserve	VBN
cord-260708-l9w5jhsw	204	29	active	active	JJ
cord-260708-l9w5jhsw	204	30	site	site	NN
cord-260708-l9w5jhsw	204	31	residues	residue	NNS
cord-260708-l9w5jhsw	204	32	that	that	WDT
cord-260708-l9w5jhsw	204	33	are	be	VBP
cord-260708-l9w5jhsw	204	34	critical	critical	JJ
cord-260708-l9w5jhsw	204	35	for	for	IN
cord-260708-l9w5jhsw	204	36	its	-PRON-	PRP$
cord-260708-l9w5jhsw	204	37	catalytic	catalytic	JJ
cord-260708-l9w5jhsw	204	38	activity	activity	NN
cord-260708-l9w5jhsw	204	39	have	have	VBP
cord-260708-l9w5jhsw	204	40	been	be	VBN
cord-260708-l9w5jhsw	204	41	identified	identify	VBN
cord-260708-l9w5jhsw	204	42	[	[	-LRB-
cord-260708-l9w5jhsw	204	43	10	10	CD
cord-260708-l9w5jhsw	204	44	,	,	,
cord-260708-l9w5jhsw	204	45	69	69	CD
cord-260708-l9w5jhsw	204	46	,	,	,
cord-260708-l9w5jhsw	204	47	84	84	CD
cord-260708-l9w5jhsw	204	48	]	]	-RRB-
cord-260708-l9w5jhsw	204	49	.	.	.
cord-260708-l9w5jhsw	205	1	In	in	IN
cord-260708-l9w5jhsw	205	2	the	the	DT
cord-260708-l9w5jhsw	205	3	last	last	JJ
cord-260708-l9w5jhsw	205	4	few	few	JJ
cord-260708-l9w5jhsw	205	5	years	year	NNS
cord-260708-l9w5jhsw	205	6	,	,	,
cord-260708-l9w5jhsw	205	7	the	the	DT
cord-260708-l9w5jhsw	205	8	crystal	crystal	NN
cord-260708-l9w5jhsw	205	9	structures	structure	NNS
cord-260708-l9w5jhsw	205	10	of	of	IN
cord-260708-l9w5jhsw	205	11	the	the	DT
cord-260708-l9w5jhsw	205	12	OTU	OTU	NNP
cord-260708-l9w5jhsw	205	13	domain	domain	NN
cord-260708-l9w5jhsw	205	14	with	with	IN
cord-260708-l9w5jhsw	205	15	and	and	CC
cord-260708-l9w5jhsw	205	16	without	without	IN
cord-260708-l9w5jhsw	205	17	a	a	DT
cord-260708-l9w5jhsw	205	18	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	205	19	molecule	molecule	NN
cord-260708-l9w5jhsw	205	20	have	have	VBP
cord-260708-l9w5jhsw	205	21	been	be	VBN
cord-260708-l9w5jhsw	205	22	determined	determine	VBN
cord-260708-l9w5jhsw	205	23	[	[	-LRB-
cord-260708-l9w5jhsw	205	24	2	2	CD
cord-260708-l9w5jhsw	205	25	,	,	,
cord-260708-l9w5jhsw	205	26	29	29	CD
cord-260708-l9w5jhsw	205	27	,	,	,
cord-260708-l9w5jhsw	205	28	89	89	CD
cord-260708-l9w5jhsw	205	29	]	]	-RRB-
cord-260708-l9w5jhsw	205	30	.	.	.
cord-260708-l9w5jhsw	206	1	The	the	DT
cord-260708-l9w5jhsw	206	2	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	206	3	OTU	OTU	NNP
cord-260708-l9w5jhsw	206	4	showed	show	VBD
cord-260708-l9w5jhsw	206	5	an	an	DT
cord-260708-l9w5jhsw	206	6	overall	overall	JJ
cord-260708-l9w5jhsw	206	7	similar	similar	JJ
cord-260708-l9w5jhsw	206	8	structure	structure	NN
cord-260708-l9w5jhsw	206	9	to	to	IN
cord-260708-l9w5jhsw	206	10	yeast	yeast	NN
cord-260708-l9w5jhsw	206	11	Otu1	Otu1	NNP
cord-260708-l9w5jhsw	206	12	,	,	,
cord-260708-l9w5jhsw	206	13	but	but	CC
cord-260708-l9w5jhsw	206	14	with	with	IN
cord-260708-l9w5jhsw	206	15	an	an	DT
cord-260708-l9w5jhsw	206	16	additional	additional	JJ
cord-260708-l9w5jhsw	206	17	domain	domain	NN
cord-260708-l9w5jhsw	206	18	formed	form	VBN
cord-260708-l9w5jhsw	206	19	by	by	IN
cord-260708-l9w5jhsw	206	20	two	two	CD
cord-260708-l9w5jhsw	206	21	antiparallel	antiparallel	NN
cord-260708-l9w5jhsw	206	22	b	b	NN
cord-260708-l9w5jhsw	206	23	-	-	HYPH
cord-260708-l9w5jhsw	206	24	strands	strand	NNS
cord-260708-l9w5jhsw	206	25	that	that	WDT
cord-260708-l9w5jhsw	206	26	allow	allow	VBP
cord-260708-l9w5jhsw	206	27	the	the	DT
cord-260708-l9w5jhsw	206	28	viral	viral	JJ
cord-260708-l9w5jhsw	206	29	OTUs	otu	NNS
cord-260708-l9w5jhsw	206	30	to	to	TO
cord-260708-l9w5jhsw	206	31	bind	bind	VB
cord-260708-l9w5jhsw	206	32	both	both	CC
cord-260708-l9w5jhsw	206	33	Ub	Ub	NNP
cord-260708-l9w5jhsw	206	34	and	and	CC
cord-260708-l9w5jhsw	206	35	ISG15	isg15	NN
cord-260708-l9w5jhsw	206	36	[	[	-LRB-
cord-260708-l9w5jhsw	206	37	2	2	CD
cord-260708-l9w5jhsw	206	38	,	,	,
cord-260708-l9w5jhsw	206	39	89	89	CD
cord-260708-l9w5jhsw	206	40	]	]	-RRB-
cord-260708-l9w5jhsw	206	41	.	.	.
cord-260708-l9w5jhsw	207	1	Specific	specific	JJ
cord-260708-l9w5jhsw	207	2	cleavage	cleavage	NN
cord-260708-l9w5jhsw	207	3	targets	target	NNS
cord-260708-l9w5jhsw	207	4	,	,	,
cord-260708-l9w5jhsw	207	5	other	other	JJ
cord-260708-l9w5jhsw	207	6	than	than	IN
cord-260708-l9w5jhsw	207	7	host	host	NN
cord-260708-l9w5jhsw	207	8	ubiquitinated	ubiquitinate	VBN
cord-260708-l9w5jhsw	207	9	or	or	CC
cord-260708-l9w5jhsw	207	10	ISGylated	isgylate	VBN
cord-260708-l9w5jhsw	207	11	proteins	protein	NNS
cord-260708-l9w5jhsw	207	12	,	,	,
cord-260708-l9w5jhsw	207	13	for	for	IN
cord-260708-l9w5jhsw	207	14	the	the	DT
cord-260708-l9w5jhsw	207	15	viral	viral	JJ
cord-260708-l9w5jhsw	207	16	OTU	otu	NN
cord-260708-l9w5jhsw	207	17	-	-	HYPH
cord-260708-l9w5jhsw	207	18	like	like	JJ
cord-260708-l9w5jhsw	207	19	protease	protease	NN
cord-260708-l9w5jhsw	207	20	have	have	VBP
cord-260708-l9w5jhsw	207	21	not	not	RB
cord-260708-l9w5jhsw	207	22	yet	yet	RB
cord-260708-l9w5jhsw	207	23	been	be	VBN
cord-260708-l9w5jhsw	207	24	described	describe	VBN
cord-260708-l9w5jhsw	207	25	.	.	.
cord-260708-l9w5jhsw	208	1	As	as	IN
cord-260708-l9w5jhsw	208	2	several	several	JJ
cord-260708-l9w5jhsw	208	3	potential	potential	JJ
cord-260708-l9w5jhsw	208	4	cysteine	cysteine	NN
cord-260708-l9w5jhsw	208	5	-	-	HYPH
cord-260708-l9w5jhsw	208	6	protease	protease	NN
cord-260708-l9w5jhsw	208	7	-	-	HYPH
cord-260708-l9w5jhsw	208	8	like	like	JJ
cord-260708-l9w5jhsw	208	9	cleavage	cleavage	NN
cord-260708-l9w5jhsw	208	10	sites	site	NNS
cord-260708-l9w5jhsw	208	11	have	have	VBP
cord-260708-l9w5jhsw	208	12	been	be	VBN
cord-260708-l9w5jhsw	208	13	identified	identify	VBN
cord-260708-l9w5jhsw	208	14	in	in	IN
cord-260708-l9w5jhsw	208	15	the	the	DT
cord-260708-l9w5jhsw	208	16	L	L	NNP
cord-260708-l9w5jhsw	208	17	protein	protein	NN
cord-260708-l9w5jhsw	208	18	sequence	sequence	NN
cord-260708-l9w5jhsw	208	19	of	of	IN
cord-260708-l9w5jhsw	208	20	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	208	21	[	[	-LRB-
cord-260708-l9w5jhsw	208	22	94	94	CD
cord-260708-l9w5jhsw	208	23	]	]	-RRB-
cord-260708-l9w5jhsw	208	24	and	and	CC
cord-260708-l9w5jhsw	208	25	some	some	DT
cord-260708-l9w5jhsw	208	26	viral	viral	JJ
cord-260708-l9w5jhsw	208	27	proteins	protein	NNS
cord-260708-l9w5jhsw	208	28	containing	contain	VBG
cord-260708-l9w5jhsw	208	29	an	an	DT
cord-260708-l9w5jhsw	208	30	OTU	OTU	NNP
cord-260708-l9w5jhsw	208	31	-	-	HYPH
cord-260708-l9w5jhsw	208	32	like	like	JJ
cord-260708-l9w5jhsw	208	33	protease	protease	NN
cord-260708-l9w5jhsw	208	34	domain	domain	NN
cord-260708-l9w5jhsw	208	35	have	have	VBP
cord-260708-l9w5jhsw	208	36	also	also	RB
cord-260708-l9w5jhsw	208	37	been	be	VBN
cord-260708-l9w5jhsw	208	38	shown	show	VBN
cord-260708-l9w5jhsw	208	39	to	to	TO
cord-260708-l9w5jhsw	208	40	undergo	undergo	VB
cord-260708-l9w5jhsw	208	41	autoproteolytic	autoproteolytic	JJ
cord-260708-l9w5jhsw	208	42	cleavage	cleavage	NN
cord-260708-l9w5jhsw	208	43	to	to	TO
cord-260708-l9w5jhsw	208	44	generate	generate	VB
cord-260708-l9w5jhsw	208	45	multiple	multiple	JJ
cord-260708-l9w5jhsw	208	46	mature	mature	JJ
cord-260708-l9w5jhsw	208	47	proteins	protein	NNS
cord-260708-l9w5jhsw	208	48	,	,	,
cord-260708-l9w5jhsw	209	1	e.g.	e.g.	RB
cord-260708-l9w5jhsw	209	2	,	,	,
cord-260708-l9w5jhsw	209	3	the	the	DT
cord-260708-l9w5jhsw	209	4	replicase	replicase	NN
cord-260708-l9w5jhsw	209	5	of	of	IN
cord-260708-l9w5jhsw	209	6	BlScV	BlScV	NNP
cord-260708-l9w5jhsw	209	7	[	[	-LRB-
cord-260708-l9w5jhsw	209	8	98	98	CD
cord-260708-l9w5jhsw	209	9	]	]	-RRB-
cord-260708-l9w5jhsw	209	10	,	,	,
cord-260708-l9w5jhsw	209	11	it	-PRON-	PRP
cord-260708-l9w5jhsw	209	12	has	have	VBZ
cord-260708-l9w5jhsw	209	13	been	be	VBN
cord-260708-l9w5jhsw	209	14	suggested	suggest	VBN
cord-260708-l9w5jhsw	209	15	that	that	IN
cord-260708-l9w5jhsw	209	16	the	the	DT
cord-260708-l9w5jhsw	209	17	L	L	NNP
cord-260708-l9w5jhsw	209	18	proteins	protein	NNS
cord-260708-l9w5jhsw	209	19	of	of	IN
cord-260708-l9w5jhsw	209	20	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	209	21	may	may	MD
cord-260708-l9w5jhsw	209	22	also	also	RB
cord-260708-l9w5jhsw	209	23	be	be	VB
cord-260708-l9w5jhsw	209	24	autoproteolytically	autoproteolytically	RB
cord-260708-l9w5jhsw	209	25	cleaved	cleave	VBN
cord-260708-l9w5jhsw	209	26	into	into	IN
cord-260708-l9w5jhsw	209	27	an	an	DT
cord-260708-l9w5jhsw	209	28	active	active	JJ
cord-260708-l9w5jhsw	209	29	RNA	RNA	NNP
cord-260708-l9w5jhsw	209	30	polymerase	polymerase	NN
cord-260708-l9w5jhsw	209	31	and	and	CC
cord-260708-l9w5jhsw	209	32	protein(s	protein(s	NNP
cord-260708-l9w5jhsw	209	33	)	)	-RRB-
cord-260708-l9w5jhsw	209	34	with	with	IN
cord-260708-l9w5jhsw	209	35	additional	additional	JJ
cord-260708-l9w5jhsw	209	36	function	function	NN
cord-260708-l9w5jhsw	209	37	[	[	-LRB-
cord-260708-l9w5jhsw	209	38	85	85	CD
cord-260708-l9w5jhsw	209	39	]	]	-RRB-
cord-260708-l9w5jhsw	209	40	.	.	.
cord-260708-l9w5jhsw	210	1	We	-PRON-	PRP
cord-260708-l9w5jhsw	210	2	have	have	VBP
cord-260708-l9w5jhsw	210	3	raised	raise	VBN
cord-260708-l9w5jhsw	210	4	specific	specific	JJ
cord-260708-l9w5jhsw	210	5	antibodies	antibody	NNS
cord-260708-l9w5jhsw	210	6	to	to	IN
cord-260708-l9w5jhsw	210	7	the	the	DT
cord-260708-l9w5jhsw	210	8	Nand	Nand	NNP
cord-260708-l9w5jhsw	210	9	C	C	NNP
cord-260708-l9w5jhsw	210	10	-	-	HYPH
cord-260708-l9w5jhsw	210	11	termini	termini	NNP
cord-260708-l9w5jhsw	210	12	of	of	IN
cord-260708-l9w5jhsw	210	13	the	the	DT
cord-260708-l9w5jhsw	210	14	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	210	15	L	L	NNP
cord-260708-l9w5jhsw	210	16	protein	protein	NN
cord-260708-l9w5jhsw	210	17	and	and	CC
cord-260708-l9w5jhsw	210	18	shown	show	VBN
cord-260708-l9w5jhsw	210	19	that	that	IN
cord-260708-l9w5jhsw	210	20	such	such	JJ
cord-260708-l9w5jhsw	210	21	cleavage	cleavage	NN
cord-260708-l9w5jhsw	210	22	does	do	VBZ
cord-260708-l9w5jhsw	210	23	not	not	RB
cord-260708-l9w5jhsw	210	24	occur	occur	VB
cord-260708-l9w5jhsw	210	25	in	in	IN
cord-260708-l9w5jhsw	210	26	infected	infected	JJ
cord-260708-l9w5jhsw	210	27	cells	cell	NNS
cord-260708-l9w5jhsw	210	28	(	(	-LRB-
cord-260708-l9w5jhsw	210	29	Lasecka	Lasecka	NNPS
cord-260708-l9w5jhsw	210	30	and	and	CC
cord-260708-l9w5jhsw	210	31	Baron	Baron	NNP
cord-260708-l9w5jhsw	210	32	,	,	,
cord-260708-l9w5jhsw	210	33	unpublished	unpublished	JJ
cord-260708-l9w5jhsw	210	34	)	)	-RRB-
cord-260708-l9w5jhsw	210	35	.	.	.
cord-260708-l9w5jhsw	211	1	Early	early	JJ
cord-260708-l9w5jhsw	211	2	studies	study	NNS
cord-260708-l9w5jhsw	211	3	on	on	IN
cord-260708-l9w5jhsw	211	4	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	211	5	showed	show	VBD
cord-260708-l9w5jhsw	211	6	that	that	IN
cord-260708-l9w5jhsw	211	7	,	,	,
cord-260708-l9w5jhsw	211	8	unlike	unlike	IN
cord-260708-l9w5jhsw	211	9	other	other	JJ
cord-260708-l9w5jhsw	211	10	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	211	11	,	,	,
cord-260708-l9w5jhsw	211	12	they	-PRON-	PRP
cord-260708-l9w5jhsw	211	13	do	do	VBP
cord-260708-l9w5jhsw	211	14	not	not	RB
cord-260708-l9w5jhsw	211	15	shut	shut	VB
cord-260708-l9w5jhsw	211	16	off	off	RP
cord-260708-l9w5jhsw	211	17	host	host	NN
cord-260708-l9w5jhsw	211	18	protein	protein	NN
cord-260708-l9w5jhsw	211	19	synthesis	synthesis	NN
cord-260708-l9w5jhsw	211	20	[	[	-LRB-
cord-260708-l9w5jhsw	211	21	33	33	CD
cord-260708-l9w5jhsw	211	22	,	,	,
cord-260708-l9w5jhsw	211	23	176	176	CD
cord-260708-l9w5jhsw	211	24	]	]	-RRB-
cord-260708-l9w5jhsw	211	25	,	,	,
cord-260708-l9w5jhsw	211	26	so	so	IN
cord-260708-l9w5jhsw	211	27	the	the	DT
cord-260708-l9w5jhsw	211	28	viruses	virus	NNS
cord-260708-l9w5jhsw	211	29	must	must	MD
cord-260708-l9w5jhsw	211	30	have	have	VB
cord-260708-l9w5jhsw	211	31	a	a	DT
cord-260708-l9w5jhsw	211	32	different	different	JJ
cord-260708-l9w5jhsw	211	33	way	way	NN
cord-260708-l9w5jhsw	211	34	of	of	IN
cord-260708-l9w5jhsw	211	35	controlling	control	VBG
cord-260708-l9w5jhsw	211	36	the	the	DT
cord-260708-l9w5jhsw	211	37	immediate	immediate	JJ
cord-260708-l9w5jhsw	211	38	host	host	NN
cord-260708-l9w5jhsw	211	39	cell	cell	NN
cord-260708-l9w5jhsw	211	40	responses	response	NNS
cord-260708-l9w5jhsw	211	41	to	to	IN
cord-260708-l9w5jhsw	211	42	infection	infection	NN
cord-260708-l9w5jhsw	211	43	,	,	,
cord-260708-l9w5jhsw	211	44	such	such	JJ
cord-260708-l9w5jhsw	211	45	as	as	IN
cord-260708-l9w5jhsw	211	46	the	the	DT
cord-260708-l9w5jhsw	211	47	innate	innate	JJ
cord-260708-l9w5jhsw	211	48	immune	immune	JJ
cord-260708-l9w5jhsw	211	49	response	response	NN
cord-260708-l9w5jhsw	211	50	and	and	CC
cord-260708-l9w5jhsw	211	51	apoptosis	apoptosis	NN
cord-260708-l9w5jhsw	211	52	.	.	.
cord-260708-l9w5jhsw	212	1	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	212	2	infection	infection	NN
cord-260708-l9w5jhsw	212	3	in	in	IN
cord-260708-l9w5jhsw	212	4	cultured	cultured	JJ
cord-260708-l9w5jhsw	212	5	cells	cell	NNS
cord-260708-l9w5jhsw	212	6	induced	induce	VBN
cord-260708-l9w5jhsw	212	7	apoptosis	apoptosis	NN
cord-260708-l9w5jhsw	212	8	,	,	,
cord-260708-l9w5jhsw	212	9	albeit	albeit	IN
cord-260708-l9w5jhsw	212	10	at	at	IN
cord-260708-l9w5jhsw	212	11	late	late	JJ
cord-260708-l9w5jhsw	212	12	stages	stage	NNS
cord-260708-l9w5jhsw	212	13	of	of	IN
cord-260708-l9w5jhsw	212	14	infection	infection	NN
cord-260708-l9w5jhsw	212	15	[	[	-LRB-
cord-260708-l9w5jhsw	212	16	91	91	CD
cord-260708-l9w5jhsw	212	17	,	,	,
cord-260708-l9w5jhsw	212	18	141	141	CD
cord-260708-l9w5jhsw	212	19	]	]	-RRB-
cord-260708-l9w5jhsw	212	20	.	.	.
cord-260708-l9w5jhsw	213	1	One	one	CD
cord-260708-l9w5jhsw	213	2	of	of	IN
cord-260708-l9w5jhsw	213	3	the	the	DT
cord-260708-l9w5jhsw	213	4	ways	way	NNS
cord-260708-l9w5jhsw	213	5	in	in	IN
cord-260708-l9w5jhsw	213	6	which	which	WDT
cord-260708-l9w5jhsw	213	7	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	213	8	might	may	MD
cord-260708-l9w5jhsw	213	9	induce	induce	VB
cord-260708-l9w5jhsw	213	10	apoptosis	apoptosis	NN
cord-260708-l9w5jhsw	213	11	has	have	VBZ
cord-260708-l9w5jhsw	213	12	been	be	VBN
cord-260708-l9w5jhsw	213	13	suggested	suggest	VBN
cord-260708-l9w5jhsw	213	14	to	to	TO
cord-260708-l9w5jhsw	213	15	be	be	VB
cord-260708-l9w5jhsw	213	16	via	via	IN
cord-260708-l9w5jhsw	213	17	the	the	DT
cord-260708-l9w5jhsw	213	18	induction	induction	NN
cord-260708-l9w5jhsw	213	19	of	of	IN
cord-260708-l9w5jhsw	213	20	ER	ER	NNP
cord-260708-l9w5jhsw	213	21	stress	stress	NN
cord-260708-l9w5jhsw	213	22	[	[	-LRB-
cord-260708-l9w5jhsw	213	23	141	141	CD
cord-260708-l9w5jhsw	213	24	]	]	-RRB-
cord-260708-l9w5jhsw	213	25	.	.	.
cord-260708-l9w5jhsw	214	1	Certainly	certainly	RB
cord-260708-l9w5jhsw	214	2	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	214	3	and	and	CC
cord-260708-l9w5jhsw	214	4	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	214	5	have	have	VBP
cord-260708-l9w5jhsw	214	6	both	both	DT
cord-260708-l9w5jhsw	214	7	been	be	VBN
cord-260708-l9w5jhsw	214	8	shown	show	VBN
cord-260708-l9w5jhsw	214	9	to	to	TO
cord-260708-l9w5jhsw	214	10	induce	induce	VB
cord-260708-l9w5jhsw	214	11	ER	ER	NNP
cord-260708-l9w5jhsw	214	12	stress	stress	NN
cord-260708-l9w5jhsw	214	13	[	[	-LRB-
cord-260708-l9w5jhsw	214	14	141	141	CD
cord-260708-l9w5jhsw	214	15	]	]	-RRB-
cord-260708-l9w5jhsw	214	16	,	,	,
cord-260708-l9w5jhsw	214	17	and	and	CC
cord-260708-l9w5jhsw	214	18	we	-PRON-	PRP
cord-260708-l9w5jhsw	214	19	have	have	VBP
cord-260708-l9w5jhsw	214	20	observed	observe	VBN
cord-260708-l9w5jhsw	214	21	the	the	DT
cord-260708-l9w5jhsw	214	22	same	same	JJ
cord-260708-l9w5jhsw	214	23	in	in	IN
cord-260708-l9w5jhsw	214	24	cells	cell	NNS
cord-260708-l9w5jhsw	214	25	infected	infect	VBN
cord-260708-l9w5jhsw	214	26	with	with	IN
cord-260708-l9w5jhsw	214	27	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	214	28	(	(	-LRB-
cord-260708-l9w5jhsw	214	29	Lasecka	Lasecka	NNPS
cord-260708-l9w5jhsw	214	30	,	,	,
cord-260708-l9w5jhsw	214	31	unpublished	unpublished	JJ
cord-260708-l9w5jhsw	214	32	data	datum	NNS
cord-260708-l9w5jhsw	214	33	)	)	-RRB-
cord-260708-l9w5jhsw	214	34	.	.	.
cord-260708-l9w5jhsw	215	1	During	during	IN
cord-260708-l9w5jhsw	215	2	replication	replication	NN
cord-260708-l9w5jhsw	215	3	,	,	,
cord-260708-l9w5jhsw	215	4	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	215	5	synthesise	synthesise	VBP
cord-260708-l9w5jhsw	215	6	large	large	JJ
cord-260708-l9w5jhsw	215	7	amounts	amount	NNS
cord-260708-l9w5jhsw	215	8	of	of	IN
cord-260708-l9w5jhsw	215	9	their	-PRON-	PRP$
cord-260708-l9w5jhsw	215	10	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	215	11	,	,	,
cord-260708-l9w5jhsw	215	12	which	which	WDT
cord-260708-l9w5jhsw	215	13	mature	mature	VBP
cord-260708-l9w5jhsw	215	14	in	in	IN
cord-260708-l9w5jhsw	215	15	the	the	DT
cord-260708-l9w5jhsw	215	16	ER	ER	NNP
cord-260708-l9w5jhsw	215	17	and	and	CC
cord-260708-l9w5jhsw	215	18	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	215	19	[	[	-LRB-
cord-260708-l9w5jhsw	215	20	17	17	CD
cord-260708-l9w5jhsw	215	21	,	,	,
cord-260708-l9w5jhsw	215	22	21	21	CD
cord-260708-l9w5jhsw	215	23	,	,	,
cord-260708-l9w5jhsw	215	24	142	142	CD
cord-260708-l9w5jhsw	215	25	]	]	-RRB-
cord-260708-l9w5jhsw	215	26	and	and	CC
cord-260708-l9w5jhsw	215	27	are	be	VBP
cord-260708-l9w5jhsw	215	28	likely	likely	JJ
cord-260708-l9w5jhsw	215	29	to	to	TO
cord-260708-l9w5jhsw	215	30	overload	overload	VB
cord-260708-l9w5jhsw	215	31	the	the	DT
cord-260708-l9w5jhsw	215	32	normal	normal	JJ
cord-260708-l9w5jhsw	215	33	ER	ER	NNP
cord-260708-l9w5jhsw	215	34	protein	protein	NN
cord-260708-l9w5jhsw	215	35	synthesis	synthesis	NN
cord-260708-l9w5jhsw	215	36	machinery	machinery	NN
cord-260708-l9w5jhsw	215	37	.	.	.
cord-260708-l9w5jhsw	216	1	As	as	RB
cord-260708-l9w5jhsw	216	2	long	long	RB
cord-260708-l9w5jhsw	216	3	as	as	IN
cord-260708-l9w5jhsw	216	4	the	the	DT
cord-260708-l9w5jhsw	216	5	apoptosis	apoptosis	NN
cord-260708-l9w5jhsw	216	6	occurs	occur	VBZ
cord-260708-l9w5jhsw	216	7	after	after	IN
cord-260708-l9w5jhsw	216	8	the	the	DT
cord-260708-l9w5jhsw	216	9	virus	virus	NN
cord-260708-l9w5jhsw	216	10	has	have	VBZ
cord-260708-l9w5jhsw	216	11	completed	complete	VBN
cord-260708-l9w5jhsw	216	12	the	the	DT
cord-260708-l9w5jhsw	216	13	assembly	assembly	NN
cord-260708-l9w5jhsw	216	14	and	and	CC
cord-260708-l9w5jhsw	216	15	release	release	NN
cord-260708-l9w5jhsw	216	16	of	of	IN
cord-260708-l9w5jhsw	216	17	progeny	progeny	JJ
cord-260708-l9w5jhsw	216	18	virus	virus	NN
cord-260708-l9w5jhsw	216	19	,	,	,
cord-260708-l9w5jhsw	216	20	apoptosis	apoptosis	NN
cord-260708-l9w5jhsw	216	21	is	be	VBZ
cord-260708-l9w5jhsw	216	22	not	not	RB
cord-260708-l9w5jhsw	216	23	a	a	DT
cord-260708-l9w5jhsw	216	24	major	major	JJ
cord-260708-l9w5jhsw	216	25	problem	problem	NN
cord-260708-l9w5jhsw	216	26	,	,	,
cord-260708-l9w5jhsw	216	27	but	but	CC
cord-260708-l9w5jhsw	216	28	it	-PRON-	PRP
cord-260708-l9w5jhsw	216	29	is	be	VBZ
cord-260708-l9w5jhsw	216	30	unclear	unclear	JJ
cord-260708-l9w5jhsw	216	31	as	as	IN
cord-260708-l9w5jhsw	216	32	yet	yet	RB
cord-260708-l9w5jhsw	216	33	whether	whether	IN
cord-260708-l9w5jhsw	216	34	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	216	35	take	take	VBP
cord-260708-l9w5jhsw	216	36	active	active	JJ
cord-260708-l9w5jhsw	216	37	steps	step	NNS
cord-260708-l9w5jhsw	216	38	to	to	TO
cord-260708-l9w5jhsw	216	39	inhibit	inhibit	VB
cord-260708-l9w5jhsw	216	40	apoptotic	apoptotic	JJ
cord-260708-l9w5jhsw	216	41	pathways	pathway	NNS
cord-260708-l9w5jhsw	216	42	.	.	.
cord-260708-l9w5jhsw	217	1	There	there	EX
cord-260708-l9w5jhsw	217	2	is	be	VBZ
cord-260708-l9w5jhsw	217	3	the	the	DT
cord-260708-l9w5jhsw	217	4	possibility	possibility	NN
cord-260708-l9w5jhsw	217	5	that	that	IN
cord-260708-l9w5jhsw	217	6	apoptosis	apoptosis	NN
cord-260708-l9w5jhsw	217	7	may	may	MD
cord-260708-l9w5jhsw	217	8	be	be	VB
cord-260708-l9w5jhsw	217	9	delayed	delay	VBN
cord-260708-l9w5jhsw	217	10	or	or	CC
cord-260708-l9w5jhsw	217	11	inhibited	inhibit	VBN
cord-260708-l9w5jhsw	217	12	in	in	IN
cord-260708-l9w5jhsw	217	13	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	217	14	infections	infection	NNS
cord-260708-l9w5jhsw	217	15	by	by	IN
cord-260708-l9w5jhsw	217	16	the	the	DT
cord-260708-l9w5jhsw	217	17	presence	presence	NN
cord-260708-l9w5jhsw	217	18	of	of	IN
cord-260708-l9w5jhsw	217	19	a	a	DT
cord-260708-l9w5jhsw	217	20	highly	highly	RB
cord-260708-l9w5jhsw	217	21	conserved	conserve	VBN
cord-260708-l9w5jhsw	217	22	caspase-3	caspase-3	NNP
cord-260708-l9w5jhsw	217	23	cleavage	cleavage	NN
cord-260708-l9w5jhsw	217	24	site	site	NN
cord-260708-l9w5jhsw	217	25	(	(	-LRB-
cord-260708-l9w5jhsw	217	26	DEVD	DEVD	NNP
cord-260708-l9w5jhsw	217	27	)	)	-RRB-
cord-260708-l9w5jhsw	217	28	in	in	IN
cord-260708-l9w5jhsw	217	29	the	the	DT
cord-260708-l9w5jhsw	217	30	N	N	NNP
cord-260708-l9w5jhsw	217	31	protein	protein	NN
cord-260708-l9w5jhsw	217	32	[	[	-LRB-
cord-260708-l9w5jhsw	217	33	31	31	CD
cord-260708-l9w5jhsw	217	34	,	,	,
cord-260708-l9w5jhsw	217	35	91	91	CD
cord-260708-l9w5jhsw	217	36	]	]	-RRB-
cord-260708-l9w5jhsw	217	37	,	,	,
cord-260708-l9w5jhsw	217	38	which	which	WDT
cord-260708-l9w5jhsw	217	39	may	may	MD
cord-260708-l9w5jhsw	217	40	act	act	VB
cord-260708-l9w5jhsw	217	41	as	as	IN
cord-260708-l9w5jhsw	217	42	a	a	DT
cord-260708-l9w5jhsw	217	43	decoy	decoy	NN
cord-260708-l9w5jhsw	217	44	substrate	substrate	NN
cord-260708-l9w5jhsw	217	45	for	for	IN
cord-260708-l9w5jhsw	217	46	caspase-3	caspase-3	NNP
cord-260708-l9w5jhsw	217	47	.	.	.
cord-260708-l9w5jhsw	218	1	Although	although	IN
cord-260708-l9w5jhsw	218	2	this	this	DT
cord-260708-l9w5jhsw	218	3	motif	motif	NN
cord-260708-l9w5jhsw	218	4	has	have	VBZ
cord-260708-l9w5jhsw	218	5	been	be	VBN
cord-260708-l9w5jhsw	218	6	suggested	suggest	VBN
cord-260708-l9w5jhsw	218	7	to	to	TO
cord-260708-l9w5jhsw	218	8	be	be	VB
cord-260708-l9w5jhsw	218	9	involved	involve	VBN
cord-260708-l9w5jhsw	218	10	in	in	IN
cord-260708-l9w5jhsw	218	11	control	control	NN
cord-260708-l9w5jhsw	218	12	of	of	IN
cord-260708-l9w5jhsw	218	13	apoptosis	apoptosis	NN
cord-260708-l9w5jhsw	218	14	[	[	-LRB-
cord-260708-l9w5jhsw	218	15	31	31	CD
cord-260708-l9w5jhsw	218	16	,	,	,
cord-260708-l9w5jhsw	218	17	91	91	CD
cord-260708-l9w5jhsw	218	18	]	]	-RRB-
cord-260708-l9w5jhsw	218	19	,	,	,
cord-260708-l9w5jhsw	218	20	the	the	DT
cord-260708-l9w5jhsw	218	21	cleavage	cleavage	NN
cord-260708-l9w5jhsw	218	22	of	of	IN
cord-260708-l9w5jhsw	218	23	N	n	CD
cord-260708-l9w5jhsw	218	24	protein	protein	NN
cord-260708-l9w5jhsw	218	25	by	by	IN
cord-260708-l9w5jhsw	218	26	caspase-3	caspase-3	NNP
cord-260708-l9w5jhsw	218	27	is	be	VBZ
cord-260708-l9w5jhsw	218	28	not	not	RB
cord-260708-l9w5jhsw	218	29	required	require	VBN
cord-260708-l9w5jhsw	218	30	for	for	IN
cord-260708-l9w5jhsw	218	31	replication	replication	NN
cord-260708-l9w5jhsw	218	32	/	/	SYM
cord-260708-l9w5jhsw	218	33	transcription	transcription	NN
cord-260708-l9w5jhsw	218	34	of	of	IN
cord-260708-l9w5jhsw	218	35	a	a	DT
cord-260708-l9w5jhsw	218	36	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	218	37	minigenome	minigenome	NNP
cord-260708-l9w5jhsw	218	38	[	[	-LRB-
cord-260708-l9w5jhsw	218	39	31	31	CD
cord-260708-l9w5jhsw	218	40	]	]	-RRB-
cord-260708-l9w5jhsw	218	41	.	.	.
cord-260708-l9w5jhsw	219	1	In	in	IN
cord-260708-l9w5jhsw	219	2	addition	addition	NN
cord-260708-l9w5jhsw	219	3	,	,	,
cord-260708-l9w5jhsw	219	4	this	this	DT
cord-260708-l9w5jhsw	219	5	DEVD	devd	JJ
cord-260708-l9w5jhsw	219	6	motif	motif	NN
cord-260708-l9w5jhsw	219	7	appears	appear	VBZ
cord-260708-l9w5jhsw	219	8	to	to	TO
cord-260708-l9w5jhsw	219	9	be	be	VB
cord-260708-l9w5jhsw	219	10	inaccessible	inaccessible	JJ
cord-260708-l9w5jhsw	219	11	to	to	IN
cord-260708-l9w5jhsw	219	12	caspase-3	caspase-3	NNP
cord-260708-l9w5jhsw	219	13	in	in	IN
cord-260708-l9w5jhsw	219	14	the	the	DT
cord-260708-l9w5jhsw	219	15	oligomeric	oligomeric	JJ
cord-260708-l9w5jhsw	219	16	form	form	NN
cord-260708-l9w5jhsw	219	17	of	of	IN
cord-260708-l9w5jhsw	219	18	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	219	19	N	N	NNP
cord-260708-l9w5jhsw	219	20	,	,	,
cord-260708-l9w5jhsw	219	21	suggesting	suggest	VBG
cord-260708-l9w5jhsw	219	22	that	that	IN
cord-260708-l9w5jhsw	219	23	only	only	RB
cord-260708-l9w5jhsw	219	24	N	n	CD
cord-260708-l9w5jhsw	219	25	monomers	monomer	NNS
cord-260708-l9w5jhsw	219	26	are	be	VBP
cord-260708-l9w5jhsw	219	27	caspase-3	caspase-3	NNP
cord-260708-l9w5jhsw	219	28	sensitive	sensitive	JJ
cord-260708-l9w5jhsw	219	29	[	[	-LRB-
cord-260708-l9w5jhsw	219	30	174	174	CD
cord-260708-l9w5jhsw	219	31	]	]	-RRB-
cord-260708-l9w5jhsw	219	32	.	.	.
cord-260708-l9w5jhsw	220	1	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	220	2	also	also	RB
cord-260708-l9w5jhsw	220	3	appears	appear	VBZ
cord-260708-l9w5jhsw	220	4	to	to	TO
cord-260708-l9w5jhsw	220	5	be	be	VB
cord-260708-l9w5jhsw	220	6	the	the	DT
cord-260708-l9w5jhsw	220	7	only	only	JJ
cord-260708-l9w5jhsw	220	8	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	220	9	that	that	WDT
cord-260708-l9w5jhsw	220	10	contains	contain	VBZ
cord-260708-l9w5jhsw	220	11	the	the	DT
cord-260708-l9w5jhsw	220	12	DEVD	devd	JJ
cord-260708-l9w5jhsw	220	13	motif	motif	NN
cord-260708-l9w5jhsw	220	14	[	[	-LRB-
cord-260708-l9w5jhsw	220	15	174	174	CD
cord-260708-l9w5jhsw	220	16	]	]	-RRB-
cord-260708-l9w5jhsw	220	17	;	;	:
cord-260708-l9w5jhsw	220	18	other	other	JJ
cord-260708-l9w5jhsw	220	19	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	220	20	,	,	,
cord-260708-l9w5jhsw	220	21	such	such	JJ
cord-260708-l9w5jhsw	220	22	as	as	IN
cord-260708-l9w5jhsw	220	23	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	220	24	/	/	SYM
cord-260708-l9w5jhsw	220	25	GV	GV	NNP
cord-260708-l9w5jhsw	220	26	,	,	,
cord-260708-l9w5jhsw	220	27	do	do	VBP
cord-260708-l9w5jhsw	220	28	not	not	RB
cord-260708-l9w5jhsw	220	29	have	have	VB
cord-260708-l9w5jhsw	220	30	the	the	DT
cord-260708-l9w5jhsw	220	31	motif	motif	NN
cord-260708-l9w5jhsw	220	32	,	,	,
cord-260708-l9w5jhsw	220	33	yet	yet	CC
cord-260708-l9w5jhsw	220	34	are	be	VBP
cord-260708-l9w5jhsw	220	35	still	still	RB
cord-260708-l9w5jhsw	220	36	highly	highly	RB
cord-260708-l9w5jhsw	220	37	pathogenic	pathogenic	JJ
cord-260708-l9w5jhsw	220	38	.	.	.
cord-260708-l9w5jhsw	221	1	The	the	DT
cord-260708-l9w5jhsw	221	2	innate	innate	JJ
cord-260708-l9w5jhsw	221	3	immune	immune	JJ
cord-260708-l9w5jhsw	221	4	response	response	NN
cord-260708-l9w5jhsw	221	5	to	to	IN
cord-260708-l9w5jhsw	221	6	viral	viral	JJ
cord-260708-l9w5jhsw	221	7	infection	infection	NN
cord-260708-l9w5jhsw	221	8	has	have	VBZ
cord-260708-l9w5jhsw	221	9	been	be	VBN
cord-260708-l9w5jhsw	221	10	described	describe	VBN
cord-260708-l9w5jhsw	221	11	in	in	IN
cord-260708-l9w5jhsw	221	12	a	a	DT
cord-260708-l9w5jhsw	221	13	number	number	NN
cord-260708-l9w5jhsw	221	14	of	of	IN
cord-260708-l9w5jhsw	221	15	recent	recent	JJ
cord-260708-l9w5jhsw	221	16	reviews	review	NNS
cord-260708-l9w5jhsw	221	17	[	[	-LRB-
cord-260708-l9w5jhsw	221	18	72	72	CD
cord-260708-l9w5jhsw	221	19	,	,	,
cord-260708-l9w5jhsw	221	20	105	105	CD
cord-260708-l9w5jhsw	221	21	,	,	,
cord-260708-l9w5jhsw	221	22	132	132	CD
cord-260708-l9w5jhsw	221	23	,	,	,
cord-260708-l9w5jhsw	221	24	143	143	CD
cord-260708-l9w5jhsw	221	25	]	]	-RRB-
cord-260708-l9w5jhsw	221	26	.	.	.
cord-260708-l9w5jhsw	222	1	Cells	cell	NNS
cord-260708-l9w5jhsw	222	2	detect	detect	VBP
cord-260708-l9w5jhsw	222	3	viral	viral	JJ
cord-260708-l9w5jhsw	222	4	pathogen	pathogen	NN
cord-260708-l9w5jhsw	222	5	-	-	HYPH
cord-260708-l9w5jhsw	222	6	associated	associate	VBN
cord-260708-l9w5jhsw	222	7	molecular	molecular	JJ
cord-260708-l9w5jhsw	222	8	patterns	pattern	NNS
cord-260708-l9w5jhsw	222	9	(	(	-LRB-
cord-260708-l9w5jhsw	222	10	PAMPs	pamp	NNS
cord-260708-l9w5jhsw	222	11	)	)	-RRB-
cord-260708-l9w5jhsw	222	12	(	(	-LRB-
cord-260708-l9w5jhsw	222	13	e.g.	e.g.	RB
cord-260708-l9w5jhsw	222	14	,	,	,
cord-260708-l9w5jhsw	222	15	double	double	RB
cord-260708-l9w5jhsw	222	16	-	-	HYPH
cord-260708-l9w5jhsw	222	17	stranded	strand	VBN
cord-260708-l9w5jhsw	222	18	RNA	RNA	NNP
cord-260708-l9w5jhsw	222	19	(	(	-LRB-
cord-260708-l9w5jhsw	222	20	dsRNA	dsrna	NN
cord-260708-l9w5jhsw	222	21	)	)	-RRB-
cord-260708-l9w5jhsw	222	22	or	or	CC
cord-260708-l9w5jhsw	222	23	DNA	DNA	NNP
cord-260708-l9w5jhsw	222	24	with	with	IN
cord-260708-l9w5jhsw	222	25	unmethylated	unmethylate	VBN
cord-260708-l9w5jhsw	222	26	CpG	CpG	NNP
cord-260708-l9w5jhsw	222	27	motifs	motifs	NNP
cord-260708-l9w5jhsw	222	28	)	)	-RRB-
cord-260708-l9w5jhsw	222	29	using	use	VBG
cord-260708-l9w5jhsw	222	30	pattern	pattern	NN
cord-260708-l9w5jhsw	222	31	recognition	recognition	NN
cord-260708-l9w5jhsw	222	32	receptors	receptor	NNS
cord-260708-l9w5jhsw	222	33	(	(	-LRB-
cord-260708-l9w5jhsw	222	34	PRRs	PRRs	NNP
cord-260708-l9w5jhsw	222	35	)	)	-RRB-
cord-260708-l9w5jhsw	222	36	,	,	,
cord-260708-l9w5jhsw	222	37	of	of	IN
cord-260708-l9w5jhsw	222	38	which	which	WDT
cord-260708-l9w5jhsw	222	39	the	the	DT
cord-260708-l9w5jhsw	222	40	most	most	RBS
cord-260708-l9w5jhsw	222	41	well	well	RB
cord-260708-l9w5jhsw	222	42	-	-	HYPH
cord-260708-l9w5jhsw	222	43	known	know	VBN
cord-260708-l9w5jhsw	222	44	are	be	VBP
cord-260708-l9w5jhsw	222	45	the	the	DT
cord-260708-l9w5jhsw	222	46	Toll	Toll	NNP
cord-260708-l9w5jhsw	222	47	-	-	HYPH
cord-260708-l9w5jhsw	222	48	like	like	JJ
cord-260708-l9w5jhsw	222	49	receptors	receptor	NNS
cord-260708-l9w5jhsw	222	50	(	(	-LRB-
cord-260708-l9w5jhsw	222	51	TLRs	TLRs	NNP
cord-260708-l9w5jhsw	222	52	)	)	-RRB-
cord-260708-l9w5jhsw	222	53	,	,	,
cord-260708-l9w5jhsw	222	54	which	which	WDT
cord-260708-l9w5jhsw	222	55	scan	scan	VBP
cord-260708-l9w5jhsw	222	56	extra	extra	JJ
cord-260708-l9w5jhsw	222	57	-	-	JJ
cord-260708-l9w5jhsw	222	58	cytoplasmic	cytoplasmic	JJ
cord-260708-l9w5jhsw	222	59	spaces	space	NNS
cord-260708-l9w5jhsw	222	60	including	include	VBG
cord-260708-l9w5jhsw	222	61	the	the	DT
cord-260708-l9w5jhsw	222	62	interior	interior	NN
cord-260708-l9w5jhsw	222	63	of	of	IN
cord-260708-l9w5jhsw	222	64	endosomes	endosome	NNS
cord-260708-l9w5jhsw	222	65	and	and	CC
cord-260708-l9w5jhsw	222	66	lysosomes	lysosome	NNS
cord-260708-l9w5jhsw	222	67	,	,	,
cord-260708-l9w5jhsw	222	68	and	and	CC
cord-260708-l9w5jhsw	222	69	the	the	DT
cord-260708-l9w5jhsw	222	70	cytosolic	cytosolic	JJ
cord-260708-l9w5jhsw	222	71	proteins	protein	NNS
cord-260708-l9w5jhsw	222	72	melanoma	melanoma	NN
cord-260708-l9w5jhsw	222	73	-	-	HYPH
cord-260708-l9w5jhsw	222	74	associated	associate	VBN
cord-260708-l9w5jhsw	222	75	differentiation	differentiation	NN
cord-260708-l9w5jhsw	222	76	gene-5	gene-5	VBD
cord-260708-l9w5jhsw	222	77	protein	protein	NN
cord-260708-l9w5jhsw	222	78	(	(	-LRB-
cord-260708-l9w5jhsw	222	79	MDA-5	MDA-5	NNP
cord-260708-l9w5jhsw	222	80	)	)	-RRB-
cord-260708-l9w5jhsw	222	81	and	and	CC
cord-260708-l9w5jhsw	222	82	retinoic	retinoic	JJ
cord-260708-l9w5jhsw	222	83	acidinducible	acidinducible	JJ
cord-260708-l9w5jhsw	222	84	gene	gene	NN
cord-260708-l9w5jhsw	222	85	-	-	:
cord-260708-l9w5jhsw	222	86	I	-PRON-	PRP
cord-260708-l9w5jhsw	222	87	protein	protein	NN
cord-260708-l9w5jhsw	222	88	(	(	-LRB-
cord-260708-l9w5jhsw	222	89	RIG	rig	NN
cord-260708-l9w5jhsw	222	90	-	-	:
cord-260708-l9w5jhsw	222	91	I	I	NNP
cord-260708-l9w5jhsw	222	92	)	)	-RRB-
cord-260708-l9w5jhsw	222	93	,	,	,
cord-260708-l9w5jhsw	222	94	which	which	WDT
cord-260708-l9w5jhsw	222	95	detect	detect	VBP
cord-260708-l9w5jhsw	222	96	virus	virus	NN
cord-260708-l9w5jhsw	222	97	-	-	HYPH
cord-260708-l9w5jhsw	222	98	associated	associate	VBN
cord-260708-l9w5jhsw	222	99	PAMPS	PAMPS	NNP
cord-260708-l9w5jhsw	222	100	in	in	IN
cord-260708-l9w5jhsw	222	101	the	the	DT
cord-260708-l9w5jhsw	222	102	cytoplasm	cytoplasm	NN
cord-260708-l9w5jhsw	222	103	.	.	.
cord-260708-l9w5jhsw	223	1	Recognition	recognition	NN
cord-260708-l9w5jhsw	223	2	of	of	IN
cord-260708-l9w5jhsw	223	3	a	a	DT
cord-260708-l9w5jhsw	223	4	PAMP	pamp	NN
cord-260708-l9w5jhsw	223	5	leads	lead	VBZ
cord-260708-l9w5jhsw	223	6	to	to	IN
cord-260708-l9w5jhsw	223	7	activation	activation	NN
cord-260708-l9w5jhsw	223	8	of	of	IN
cord-260708-l9w5jhsw	223	9	the	the	DT
cord-260708-l9w5jhsw	223	10	PRR	PRR	NNP
cord-260708-l9w5jhsw	223	11	,	,	,
cord-260708-l9w5jhsw	223	12	followed	follow	VBN
cord-260708-l9w5jhsw	223	13	by	by	IN
cord-260708-l9w5jhsw	223	14	an	an	DT
cord-260708-l9w5jhsw	223	15	intracellular	intracellular	JJ
cord-260708-l9w5jhsw	223	16	signalling	signal	VBG
cord-260708-l9w5jhsw	223	17	cascade	cascade	NN
cord-260708-l9w5jhsw	223	18	leading	lead	VBG
cord-260708-l9w5jhsw	223	19	to	to	IN
cord-260708-l9w5jhsw	223	20	the	the	DT
cord-260708-l9w5jhsw	223	21	transcription	transcription	NN
cord-260708-l9w5jhsw	223	22	of	of	IN
cord-260708-l9w5jhsw	223	23	interferon	interferon	NN
cord-260708-l9w5jhsw	223	24	b	b	NN
cord-260708-l9w5jhsw	223	25	(	(	-LRB-
cord-260708-l9w5jhsw	223	26	IFNb	IFNb	NNPS
cord-260708-l9w5jhsw	223	27	)	)	-RRB-
cord-260708-l9w5jhsw	223	28	mRNA	mrna	NN
cord-260708-l9w5jhsw	223	29	.	.	.
cord-260708-l9w5jhsw	224	1	Secreted	secreted	JJ
cord-260708-l9w5jhsw	224	2	IFNb	IFNb	NNS
cord-260708-l9w5jhsw	224	3	works	work	NNS
cord-260708-l9w5jhsw	224	4	in	in	IN
cord-260708-l9w5jhsw	224	5	an	an	DT
cord-260708-l9w5jhsw	224	6	autocrine	autocrine	JJ
cord-260708-l9w5jhsw	224	7	and	and	CC
cord-260708-l9w5jhsw	224	8	paracrine	paracrine	JJ
cord-260708-l9w5jhsw	224	9	manner	manner	NN
cord-260708-l9w5jhsw	224	10	by	by	IN
cord-260708-l9w5jhsw	224	11	binding	bind	VBG
cord-260708-l9w5jhsw	224	12	to	to	IN
cord-260708-l9w5jhsw	224	13	the	the	DT
cord-260708-l9w5jhsw	224	14	IFNa	IFNa	NNS
cord-260708-l9w5jhsw	224	15	/	/	SYM
cord-260708-l9w5jhsw	224	16	b	b	NN
cord-260708-l9w5jhsw	224	17	receptor	receptor	NN
cord-260708-l9w5jhsw	224	18	of	of	IN
cord-260708-l9w5jhsw	224	19	both	both	CC
cord-260708-l9w5jhsw	224	20	infected	infected	JJ
cord-260708-l9w5jhsw	224	21	and	and	CC
cord-260708-l9w5jhsw	224	22	uninfected	uninfected	JJ
cord-260708-l9w5jhsw	224	23	cells	cell	NNS
cord-260708-l9w5jhsw	224	24	.	.	.
cord-260708-l9w5jhsw	225	1	This	this	DT
cord-260708-l9w5jhsw	225	2	in	in	IN
cord-260708-l9w5jhsw	225	3	turn	turn	NN
cord-260708-l9w5jhsw	225	4	activates	activate	VBZ
cord-260708-l9w5jhsw	225	5	a	a	DT
cord-260708-l9w5jhsw	225	6	signalling	signal	VBG
cord-260708-l9w5jhsw	225	7	pathway	pathway	NN
cord-260708-l9w5jhsw	225	8	,	,	,
cord-260708-l9w5jhsw	225	9	which	which	WDT
cord-260708-l9w5jhsw	225	10	up	up	RB
cord-260708-l9w5jhsw	225	11	-	-	HYPH
cord-260708-l9w5jhsw	225	12	regulates	regulate	VBZ
cord-260708-l9w5jhsw	225	13	interferon	interferon	NN
cord-260708-l9w5jhsw	225	14	-	-	HYPH
cord-260708-l9w5jhsw	225	15	stimulated	stimulate	VBN
cord-260708-l9w5jhsw	225	16	genes	gene	NNS
cord-260708-l9w5jhsw	225	17	(	(	-LRB-
cord-260708-l9w5jhsw	225	18	ISGs	ISGs	NNP
cord-260708-l9w5jhsw	225	19	)	)	-RRB-
cord-260708-l9w5jhsw	225	20	,	,	,
cord-260708-l9w5jhsw	225	21	including	include	VBG
cord-260708-l9w5jhsw	225	22	IFNa	IFNa	NNS
cord-260708-l9w5jhsw	225	23	,	,	,
cord-260708-l9w5jhsw	225	24	which	which	WDT
cord-260708-l9w5jhsw	225	25	increases	increase	VBZ
cord-260708-l9w5jhsw	225	26	the	the	DT
cord-260708-l9w5jhsw	225	27	stimulus	stimulus	NN
cord-260708-l9w5jhsw	225	28	to	to	IN
cord-260708-l9w5jhsw	225	29	other	other	JJ
cord-260708-l9w5jhsw	225	30	ISGs	isg	NNS
cord-260708-l9w5jhsw	225	31	.	.	.
cord-260708-l9w5jhsw	226	1	Finally	finally	RB
cord-260708-l9w5jhsw	226	2	,	,	,
cord-260708-l9w5jhsw	226	3	the	the	DT
cord-260708-l9w5jhsw	226	4	products	product	NNS
cord-260708-l9w5jhsw	226	5	of	of	IN
cord-260708-l9w5jhsw	226	6	ISGs	ISGs	NNPS
cord-260708-l9w5jhsw	226	7	(	(	-LRB-
cord-260708-l9w5jhsw	226	8	directly	directly	RB
cord-260708-l9w5jhsw	226	9	or	or	CC
cord-260708-l9w5jhsw	226	10	indirectly	indirectly	RB
cord-260708-l9w5jhsw	226	11	)	)	-RRB-
cord-260708-l9w5jhsw	226	12	lead	lead	VBP
cord-260708-l9w5jhsw	226	13	to	to	IN
cord-260708-l9w5jhsw	226	14	the	the	DT
cord-260708-l9w5jhsw	226	15	cell	cell	NN
cord-260708-l9w5jhsw	226	16	entering	enter	VBG
cord-260708-l9w5jhsw	226	17	the	the	DT
cord-260708-l9w5jhsw	226	18	so	so	RB
cord-260708-l9w5jhsw	226	19	-	-	HYPH
cord-260708-l9w5jhsw	226	20	called	call	VBN
cord-260708-l9w5jhsw	226	21	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	226	22	state	state	NN
cord-260708-l9w5jhsw	226	23	,	,	,
cord-260708-l9w5jhsw	226	24	in	in	IN
cord-260708-l9w5jhsw	226	25	which	which	WDT
cord-260708-l9w5jhsw	226	26	many	many	JJ
cord-260708-l9w5jhsw	226	27	proteins	protein	NNS
cord-260708-l9w5jhsw	226	28	are	be	VBP
cord-260708-l9w5jhsw	226	29	present	present	JJ
cord-260708-l9w5jhsw	226	30	that	that	WDT
cord-260708-l9w5jhsw	226	31	can	can	MD
cord-260708-l9w5jhsw	226	32	inhibit	inhibit	VB
cord-260708-l9w5jhsw	226	33	different	different	JJ
cord-260708-l9w5jhsw	226	34	viruses	virus	NNS
cord-260708-l9w5jhsw	226	35	.	.	.
cord-260708-l9w5jhsw	227	1	Interferon	interferon	NN
cord-260708-l9w5jhsw	227	2	and	and	CC
cord-260708-l9w5jhsw	227	3	its	-PRON-	PRP$
cord-260708-l9w5jhsw	227	4	actions	action	NNS
cord-260708-l9w5jhsw	227	5	have	have	VBP
cord-260708-l9w5jhsw	227	6	strong	strong	JJ
cord-260708-l9w5jhsw	227	7	inhibitory	inhibitory	JJ
cord-260708-l9w5jhsw	227	8	effects	effect	NNS
cord-260708-l9w5jhsw	227	9	on	on	IN
cord-260708-l9w5jhsw	227	10	the	the	DT
cord-260708-l9w5jhsw	227	11	replication	replication	NN
cord-260708-l9w5jhsw	227	12	of	of	IN
cord-260708-l9w5jhsw	227	13	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	227	14	.	.	.
cord-260708-l9w5jhsw	228	1	For	for	IN
cord-260708-l9w5jhsw	228	2	instance	instance	NN
cord-260708-l9w5jhsw	228	3	,	,	,
cord-260708-l9w5jhsw	228	4	treatment	treatment	NN
cord-260708-l9w5jhsw	228	5	of	of	IN
cord-260708-l9w5jhsw	228	6	human	human	JJ
cord-260708-l9w5jhsw	228	7	endothelial	endothelial	JJ
cord-260708-l9w5jhsw	228	8	cells	cell	NNS
cord-260708-l9w5jhsw	228	9	with	with	IN
cord-260708-l9w5jhsw	228	10	IFNa	IFNa	NNS
cord-260708-l9w5jhsw	228	11	significantly	significantly	RB
cord-260708-l9w5jhsw	228	12	reduced	reduce	VBD
cord-260708-l9w5jhsw	228	13	the	the	DT
cord-260708-l9w5jhsw	228	14	yield	yield	NN
cord-260708-l9w5jhsw	228	15	of	of	IN
cord-260708-l9w5jhsw	228	16	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	228	17	[	[	-LRB-
cord-260708-l9w5jhsw	228	18	6	6	CD
cord-260708-l9w5jhsw	228	19	]	]	-RRB-
cord-260708-l9w5jhsw	228	20	,	,	,
cord-260708-l9w5jhsw	228	21	while	while	IN
cord-260708-l9w5jhsw	228	22	the	the	DT
cord-260708-l9w5jhsw	228	23	replication	replication	NN
cord-260708-l9w5jhsw	228	24	of	of	IN
cord-260708-l9w5jhsw	228	25	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	228	26	and	and	CC
cord-260708-l9w5jhsw	228	27	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	228	28	is	be	VBZ
cord-260708-l9w5jhsw	228	29	impaired	impair	VBN
cord-260708-l9w5jhsw	228	30	in	in	IN
cord-260708-l9w5jhsw	228	31	Vero	Vero	NNP
cord-260708-l9w5jhsw	228	32	cells	cell	NNS
cord-260708-l9w5jhsw	228	33	stably	stably	RB
cord-260708-l9w5jhsw	228	34	expressing	express	VBG
cord-260708-l9w5jhsw	228	35	the	the	DT
cord-260708-l9w5jhsw	228	36	human	human	JJ
cord-260708-l9w5jhsw	228	37	Mx	Mx	NNP
cord-260708-l9w5jhsw	228	38	(	(	-LRB-
cord-260708-l9w5jhsw	228	39	MxA	MxA	NNP
cord-260708-l9w5jhsw	228	40	)	)	-RRB-
cord-260708-l9w5jhsw	228	41	protein	protein	NN
cord-260708-l9w5jhsw	228	42	;	;	:
cord-260708-l9w5jhsw	228	43	MxA	MxA	NNP
cord-260708-l9w5jhsw	228	44	is	be	VBZ
cord-260708-l9w5jhsw	228	45	the	the	DT
cord-260708-l9w5jhsw	228	46	product	product	NN
cord-260708-l9w5jhsw	228	47	of	of	IN
cord-260708-l9w5jhsw	228	48	an	an	DT
cord-260708-l9w5jhsw	228	49	ISG	ISG	NNP
cord-260708-l9w5jhsw	228	50	and	and	CC
cord-260708-l9w5jhsw	228	51	appears	appear	VBZ
cord-260708-l9w5jhsw	228	52	to	to	TO
cord-260708-l9w5jhsw	228	53	act	act	VB
cord-260708-l9w5jhsw	228	54	through	through	IN
cord-260708-l9w5jhsw	228	55	sequestration	sequestration	NN
cord-260708-l9w5jhsw	228	56	of	of	IN
cord-260708-l9w5jhsw	228	57	the	the	DT
cord-260708-l9w5jhsw	228	58	N	N	NNP
cord-260708-l9w5jhsw	228	59	protein	protein	NN
cord-260708-l9w5jhsw	228	60	of	of	IN
cord-260708-l9w5jhsw	228	61	these	these	DT
cord-260708-l9w5jhsw	228	62	viruses	virus	NNS
cord-260708-l9w5jhsw	228	63	in	in	IN
cord-260708-l9w5jhsw	228	64	a	a	DT
cord-260708-l9w5jhsw	228	65	perinuclear	perinuclear	JJ
cord-260708-l9w5jhsw	228	66	region	region	NN
cord-260708-l9w5jhsw	228	67	[	[	-LRB-
cord-260708-l9w5jhsw	228	68	4	4	CD
cord-260708-l9w5jhsw	228	69	,	,	,
cord-260708-l9w5jhsw	228	70	25	25	CD
cord-260708-l9w5jhsw	228	71	]	]	-RRB-
cord-260708-l9w5jhsw	228	72	.	.	.
cord-260708-l9w5jhsw	229	1	However	however	RB
cord-260708-l9w5jhsw	229	2	,	,	,
cord-260708-l9w5jhsw	229	3	as	as	IN
cord-260708-l9w5jhsw	229	4	with	with	IN
cord-260708-l9w5jhsw	229	5	other	other	JJ
cord-260708-l9w5jhsw	229	6	viruses	virus	NNS
cord-260708-l9w5jhsw	229	7	,	,	,
cord-260708-l9w5jhsw	229	8	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	229	9	have	have	VBP
cord-260708-l9w5jhsw	229	10	developed	develop	VBN
cord-260708-l9w5jhsw	229	11	mechanisms	mechanism	NNS
cord-260708-l9w5jhsw	229	12	to	to	TO
cord-260708-l9w5jhsw	229	13	evade	evade	VB
cord-260708-l9w5jhsw	229	14	this	this	DT
cord-260708-l9w5jhsw	229	15	innate	innate	JJ
cord-260708-l9w5jhsw	229	16	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	229	17	response	response	NN
cord-260708-l9w5jhsw	229	18	.	.	.
cord-260708-l9w5jhsw	230	1	Some	some	DT
cord-260708-l9w5jhsw	230	2	of	of	IN
cord-260708-l9w5jhsw	230	3	these	these	DT
cord-260708-l9w5jhsw	230	4	mechanisms	mechanism	NNS
cord-260708-l9w5jhsw	230	5	appear	appear	VBP
cord-260708-l9w5jhsw	230	6	to	to	TO
cord-260708-l9w5jhsw	230	7	be	be	VB
cord-260708-l9w5jhsw	230	8	unique	unique	JJ
cord-260708-l9w5jhsw	230	9	to	to	IN
cord-260708-l9w5jhsw	230	10	one	one	CD
cord-260708-l9w5jhsw	230	11	virus	virus	NN
cord-260708-l9w5jhsw	230	12	;	;	:
cord-260708-l9w5jhsw	230	13	others	other	NNS
cord-260708-l9w5jhsw	230	14	appear	appear	VBP
cord-260708-l9w5jhsw	230	15	to	to	TO
cord-260708-l9w5jhsw	230	16	be	be	VB
cord-260708-l9w5jhsw	230	17	common	common	JJ
cord-260708-l9w5jhsw	230	18	to	to	IN
cord-260708-l9w5jhsw	230	19	all	all	PDT
cord-260708-l9w5jhsw	230	20	the	the	DT
cord-260708-l9w5jhsw	230	21	viruses	virus	NNS
cord-260708-l9w5jhsw	230	22	in	in	IN
cord-260708-l9w5jhsw	230	23	the	the	DT
cord-260708-l9w5jhsw	230	24	genus	genus	NN
cord-260708-l9w5jhsw	230	25	that	that	WDT
cord-260708-l9w5jhsw	230	26	have	have	VBP
cord-260708-l9w5jhsw	230	27	been	be	VBN
cord-260708-l9w5jhsw	230	28	studied	study	VBN
cord-260708-l9w5jhsw	230	29	.	.	.
cord-260708-l9w5jhsw	231	1	For	for	IN
cord-260708-l9w5jhsw	231	2	example	example	NN
cord-260708-l9w5jhsw	231	3	,	,	,
cord-260708-l9w5jhsw	231	4	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	231	5	can	can	MD
cord-260708-l9w5jhsw	231	6	delay	delay	VB
cord-260708-l9w5jhsw	231	7	IFNa	IFNa	NNS
cord-260708-l9w5jhsw	231	8	/	/	SYM
cord-260708-l9w5jhsw	231	9	b	b	NN
cord-260708-l9w5jhsw	231	10	production	production	NN
cord-260708-l9w5jhsw	231	11	in	in	IN
cord-260708-l9w5jhsw	231	12	infected	infected	JJ
cord-260708-l9w5jhsw	231	13	cells	cell	NNS
cord-260708-l9w5jhsw	231	14	;	;	:
cord-260708-l9w5jhsw	231	15	Andersson	Andersson	NNP
cord-260708-l9w5jhsw	231	16	et	et	NNP
cord-260708-l9w5jhsw	231	17	al	al	NNP
cord-260708-l9w5jhsw	231	18	.	.	NNP
cord-260708-l9w5jhsw	231	19	showed	show	VBD
cord-260708-l9w5jhsw	231	20	that	that	IN
cord-260708-l9w5jhsw	231	21	,	,	,
cord-260708-l9w5jhsw	231	22	in	in	IN
cord-260708-l9w5jhsw	231	23	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	231	24	-	-	HYPH
cord-260708-l9w5jhsw	231	25	infected	infect	VBN
cord-260708-l9w5jhsw	231	26	cells	cell	NNS
cord-260708-l9w5jhsw	231	27	,	,	,
cord-260708-l9w5jhsw	231	28	an	an	DT
cord-260708-l9w5jhsw	231	29	increase	increase	NN
cord-260708-l9w5jhsw	231	30	in	in	IN
cord-260708-l9w5jhsw	231	31	IFNb	IFNb	NNS
cord-260708-l9w5jhsw	231	32	mRNA	mrna	NN
cord-260708-l9w5jhsw	231	33	could	could	MD
cord-260708-l9w5jhsw	231	34	only	only	RB
cord-260708-l9w5jhsw	231	35	be	be	VB
cord-260708-l9w5jhsw	231	36	detected	detect	VBN
cord-260708-l9w5jhsw	231	37	48	48	CD
cord-260708-l9w5jhsw	231	38	h	h	NN
cord-260708-l9w5jhsw	231	39	after	after	IN
cord-260708-l9w5jhsw	231	40	infection	infection	NN
cord-260708-l9w5jhsw	231	41	,	,	,
cord-260708-l9w5jhsw	231	42	which	which	WDT
cord-260708-l9w5jhsw	231	43	leaves	leave	VBZ
cord-260708-l9w5jhsw	231	44	the	the	DT
cord-260708-l9w5jhsw	231	45	virus	virus	NN
cord-260708-l9w5jhsw	231	46	a	a	DT
cord-260708-l9w5jhsw	231	47	replication	replication	NN
cord-260708-l9w5jhsw	231	48	window	window	NN
cord-260708-l9w5jhsw	231	49	with	with	IN
cord-260708-l9w5jhsw	231	50	no	no	DT
cord-260708-l9w5jhsw	231	51	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	231	52	state	state	NN
cord-260708-l9w5jhsw	231	53	[	[	-LRB-
cord-260708-l9w5jhsw	231	54	7	7	CD
cord-260708-l9w5jhsw	231	55	]	]	-RRB-
cord-260708-l9w5jhsw	231	56	.	.	.
cord-260708-l9w5jhsw	232	1	This	this	DT
cord-260708-l9w5jhsw	232	2	delay	delay	NN
cord-260708-l9w5jhsw	232	3	is	be	VBZ
cord-260708-l9w5jhsw	232	4	related	relate	VBN
cord-260708-l9w5jhsw	232	5	to	to	IN
cord-260708-l9w5jhsw	232	6	a	a	DT
cord-260708-l9w5jhsw	232	7	delay	delay	NN
cord-260708-l9w5jhsw	232	8	in	in	IN
cord-260708-l9w5jhsw	232	9	translocation	translocation	NN
cord-260708-l9w5jhsw	232	10	of	of	IN
cord-260708-l9w5jhsw	232	11	the	the	DT
cord-260708-l9w5jhsw	232	12	transcription	transcription	NN
cord-260708-l9w5jhsw	232	13	factor	factor	NN
cord-260708-l9w5jhsw	232	14	interferon	interferon	NN
cord-260708-l9w5jhsw	232	15	regulatory	regulatory	JJ
cord-260708-l9w5jhsw	232	16	factor-3	factor-3	NNP
cord-260708-l9w5jhsw	232	17	(	(	-LRB-
cord-260708-l9w5jhsw	232	18	IRF-3	IRF-3	NNP
cord-260708-l9w5jhsw	232	19	)	)	-RRB-
cord-260708-l9w5jhsw	232	20	to	to	IN
cord-260708-l9w5jhsw	232	21	the	the	DT
cord-260708-l9w5jhsw	232	22	nucleus	nucleus	NN
cord-260708-l9w5jhsw	232	23	[	[	-LRB-
cord-260708-l9w5jhsw	232	24	7	7	CD
cord-260708-l9w5jhsw	232	25	]	]	-RRB-
cord-260708-l9w5jhsw	232	26	and	and	CC
cord-260708-l9w5jhsw	232	27	hence	hence	RB
cord-260708-l9w5jhsw	232	28	a	a	DT
cord-260708-l9w5jhsw	232	29	delay	delay	NN
cord-260708-l9w5jhsw	232	30	in	in	IN
cord-260708-l9w5jhsw	232	31	the	the	DT
cord-260708-l9w5jhsw	232	32	induction	induction	NN
cord-260708-l9w5jhsw	232	33	of	of	IN
cord-260708-l9w5jhsw	232	34	ISG56	ISG56	NNP
cord-260708-l9w5jhsw	232	35	,	,	,
cord-260708-l9w5jhsw	232	36	one	one	CD
cord-260708-l9w5jhsw	232	37	of	of	IN
cord-260708-l9w5jhsw	232	38	the	the	DT
cord-260708-l9w5jhsw	232	39	genes	gene	NNS
cord-260708-l9w5jhsw	232	40	whose	whose	WP$
cord-260708-l9w5jhsw	232	41	transcription	transcription	NN
cord-260708-l9w5jhsw	232	42	is	be	VBZ
cord-260708-l9w5jhsw	232	43	regulated	regulate	VBN
cord-260708-l9w5jhsw	232	44	by	by	IN
cord-260708-l9w5jhsw	232	45	IRF-3	IRF-3	NNP
cord-260708-l9w5jhsw	232	46	.	.	.
cord-260708-l9w5jhsw	233	1	The	the	DT
cord-260708-l9w5jhsw	233	2	ISG56	ISG56	NNP
cord-260708-l9w5jhsw	233	3	protein	protein	NN
cord-260708-l9w5jhsw	233	4	is	be	VBZ
cord-260708-l9w5jhsw	233	5	a	a	DT
cord-260708-l9w5jhsw	233	6	cytoplasmic	cytoplasmic	JJ
cord-260708-l9w5jhsw	233	7	protein	protein	NN
cord-260708-l9w5jhsw	233	8	(	(	-LRB-
cord-260708-l9w5jhsw	233	9	p56	p56	NN
cord-260708-l9w5jhsw	233	10	)	)	-RRB-
cord-260708-l9w5jhsw	233	11	that	that	WDT
cord-260708-l9w5jhsw	233	12	is	be	VBZ
cord-260708-l9w5jhsw	233	13	involved	involve	VBN
cord-260708-l9w5jhsw	233	14	in	in	IN
cord-260708-l9w5jhsw	233	15	the	the	DT
cord-260708-l9w5jhsw	233	16	global	global	JJ
cord-260708-l9w5jhsw	233	17	inhibition	inhibition	NN
cord-260708-l9w5jhsw	233	18	of	of	IN
cord-260708-l9w5jhsw	233	19	translation	translation	NN
cord-260708-l9w5jhsw	233	20	in	in	IN
cord-260708-l9w5jhsw	233	21	response	response	NN
cord-260708-l9w5jhsw	233	22	to	to	IN
cord-260708-l9w5jhsw	233	23	infection	infection	NN
cord-260708-l9w5jhsw	233	24	(	(	-LRB-
cord-260708-l9w5jhsw	233	25	reviewed	review	VBN
cord-260708-l9w5jhsw	233	26	in	in	IN
cord-260708-l9w5jhsw	233	27	ref	ref	NN
cord-260708-l9w5jhsw	233	28	.	.	.
cord-260708-l9w5jhsw	234	1	[	[	-LRB-
cord-260708-l9w5jhsw	234	2	63	63	CD
cord-260708-l9w5jhsw	234	3	]	]	-RRB-
cord-260708-l9w5jhsw	234	4	)	)	-RRB-
cord-260708-l9w5jhsw	234	5	.	.	.
cord-260708-l9w5jhsw	235	1	The	the	DT
cord-260708-l9w5jhsw	235	2	delay	delay	NN
cord-260708-l9w5jhsw	235	3	in	in	IN
cord-260708-l9w5jhsw	235	4	ISG56	ISG56	NNP
cord-260708-l9w5jhsw	235	5	expression	expression	NN
cord-260708-l9w5jhsw	235	6	correlates	correlate	VBZ
cord-260708-l9w5jhsw	235	7	with	with	IN
cord-260708-l9w5jhsw	235	8	earlier	early	JJR
cord-260708-l9w5jhsw	235	9	findings	finding	NNS
cord-260708-l9w5jhsw	235	10	that	that	IN
cord-260708-l9w5jhsw	235	11	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	235	12	do	do	VBP
cord-260708-l9w5jhsw	235	13	not	not	RB
cord-260708-l9w5jhsw	235	14	appear	appear	VB
cord-260708-l9w5jhsw	235	15	to	to	TO
cord-260708-l9w5jhsw	235	16	shut	shut	VB
cord-260708-l9w5jhsw	235	17	off	off	RP
cord-260708-l9w5jhsw	235	18	cellular	cellular	JJ
cord-260708-l9w5jhsw	235	19	protein	protein	NN
cord-260708-l9w5jhsw	235	20	synthesis	synthesis	NN
cord-260708-l9w5jhsw	235	21	[	[	-LRB-
cord-260708-l9w5jhsw	235	22	33	33	CD
cord-260708-l9w5jhsw	235	23	,	,	,
cord-260708-l9w5jhsw	235	24	176	176	CD
cord-260708-l9w5jhsw	235	25	]	]	-RRB-
cord-260708-l9w5jhsw	235	26	.	.	.
cord-260708-l9w5jhsw	236	1	In	in	IN
cord-260708-l9w5jhsw	236	2	contrast	contrast	NN
cord-260708-l9w5jhsw	236	3	to	to	IN
cord-260708-l9w5jhsw	236	4	the	the	DT
cord-260708-l9w5jhsw	236	5	findings	finding	NNS
cord-260708-l9w5jhsw	236	6	with	with	IN
cord-260708-l9w5jhsw	236	7	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	236	8	,	,	,
cord-260708-l9w5jhsw	236	9	IFNb	ifnb	JJ
cord-260708-l9w5jhsw	236	10	induction	induction	NN
cord-260708-l9w5jhsw	236	11	was	be	VBD
cord-260708-l9w5jhsw	236	12	seen	see	VBN
cord-260708-l9w5jhsw	236	13	in	in	IN
cord-260708-l9w5jhsw	236	14	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	236	15	/	/	SYM
cord-260708-l9w5jhsw	236	16	GV	GV	NNP
cord-260708-l9w5jhsw	236	17	-	-	HYPH
cord-260708-l9w5jhsw	236	18	infected	infect	VBN
cord-260708-l9w5jhsw	236	19	cells	cell	NNS
cord-260708-l9w5jhsw	236	20	after	after	IN
cord-260708-l9w5jhsw	236	21	about	about	RB
cord-260708-l9w5jhsw	236	22	16	16	CD
cord-260708-l9w5jhsw	236	23	hours	hour	NNS
cord-260708-l9w5jhsw	236	24	;	;	:
cord-260708-l9w5jhsw	236	25	however	however	RB
cord-260708-l9w5jhsw	236	26	,	,	,
cord-260708-l9w5jhsw	236	27	during	during	IN
cord-260708-l9w5jhsw	236	28	those	those	DT
cord-260708-l9w5jhsw	236	29	16	16	CD
cord-260708-l9w5jhsw	236	30	hours	hour	NNS
cord-260708-l9w5jhsw	236	31	,	,	,
cord-260708-l9w5jhsw	236	32	the	the	DT
cord-260708-l9w5jhsw	236	33	virus	virus	NN
cord-260708-l9w5jhsw	236	34	actively	actively	RB
cord-260708-l9w5jhsw	236	35	blocked	block	VBD
cord-260708-l9w5jhsw	236	36	induction	induction	NN
cord-260708-l9w5jhsw	236	37	of	of	IN
cord-260708-l9w5jhsw	236	38	IFNb	IFNb	NNS
cord-260708-l9w5jhsw	236	39	[	[	-LRB-
cord-260708-l9w5jhsw	236	40	84	84	CD
cord-260708-l9w5jhsw	236	41	]	]	-RRB-
cord-260708-l9w5jhsw	236	42	.	.	.
cord-260708-l9w5jhsw	237	1	NSDV/	NSDV/	NNP
cord-260708-l9w5jhsw	237	2	GV	GV	NNP
cord-260708-l9w5jhsw	237	3	infection	infection	NN
cord-260708-l9w5jhsw	237	4	also	also	RB
cord-260708-l9w5jhsw	237	5	blocked	block	VBD
cord-260708-l9w5jhsw	237	6	the	the	DT
cord-260708-l9w5jhsw	237	7	signalling	signal	VBG
cord-260708-l9w5jhsw	237	8	pathways	pathway	NNS
cord-260708-l9w5jhsw	237	9	activated	activate	VBN
cord-260708-l9w5jhsw	237	10	by	by	IN
cord-260708-l9w5jhsw	237	11	external	external	JJ
cord-260708-l9w5jhsw	237	12	IFNa	IFNa	NNS
cord-260708-l9w5jhsw	237	13	or	or	CC
cord-260708-l9w5jhsw	237	14	IFNc	IFNc	NNS
cord-260708-l9w5jhsw	237	15	,	,	,
cord-260708-l9w5jhsw	237	16	blocking	block	VBG
cord-260708-l9w5jhsw	237	17	the	the	DT
cord-260708-l9w5jhsw	237	18	activation	activation	NN
cord-260708-l9w5jhsw	237	19	of	of	IN
cord-260708-l9w5jhsw	237	20	transcription	transcription	NN
cord-260708-l9w5jhsw	237	21	from	from	IN
cord-260708-l9w5jhsw	237	22	promoters	promoter	NNS
cord-260708-l9w5jhsw	237	23	normally	normally	RB
cord-260708-l9w5jhsw	237	24	activated	activate	VBN
cord-260708-l9w5jhsw	237	25	by	by	IN
cord-260708-l9w5jhsw	237	26	one	one	CD
cord-260708-l9w5jhsw	237	27	or	or	CC
cord-260708-l9w5jhsw	237	28	the	the	DT
cord-260708-l9w5jhsw	237	29	other	other	JJ
cord-260708-l9w5jhsw	237	30	of	of	IN
cord-260708-l9w5jhsw	237	31	these	these	DT
cord-260708-l9w5jhsw	237	32	cytokines	cytokine	NNS
cord-260708-l9w5jhsw	237	33	by	by	IN
cord-260708-l9w5jhsw	237	34	directly	directly	RB
cord-260708-l9w5jhsw	237	35	inhibiting	inhibit	VBG
cord-260708-l9w5jhsw	237	36	the	the	DT
cord-260708-l9w5jhsw	237	37	phosphorylation	phosphorylation	NN
cord-260708-l9w5jhsw	237	38	of	of	IN
cord-260708-l9w5jhsw	237	39	the	the	DT
cord-260708-l9w5jhsw	237	40	transcription	transcription	NN
cord-260708-l9w5jhsw	237	41	factors	factor	NNS
cord-260708-l9w5jhsw	237	42	STAT1	stat1	XX
cord-260708-l9w5jhsw	238	1	and	and	CC
cord-260708-l9w5jhsw	238	2	STAT2	STAT2	NNS
cord-260708-l9w5jhsw	238	3	[	[	-LRB-
cord-260708-l9w5jhsw	238	4	84	84	CD
cord-260708-l9w5jhsw	238	5	]	]	-RRB-
cord-260708-l9w5jhsw	238	6	.	.	.
cord-260708-l9w5jhsw	239	1	Of	of	IN
cord-260708-l9w5jhsw	239	2	the	the	DT
cord-260708-l9w5jhsw	239	3	cytoplasmic	cytoplasmic	JJ
cord-260708-l9w5jhsw	239	4	PRRs	prr	NNS
cord-260708-l9w5jhsw	239	5	,	,	,
cord-260708-l9w5jhsw	239	6	RIG	rig	NN
cord-260708-l9w5jhsw	239	7	-	-	:
cord-260708-l9w5jhsw	239	8	I	-PRON-	PRP
cord-260708-l9w5jhsw	239	9	is	be	VBZ
cord-260708-l9w5jhsw	239	10	activated	activate	VBN
cord-260708-l9w5jhsw	239	11	by	by	IN
cord-260708-l9w5jhsw	239	12	RNAs	rna	NNS
cord-260708-l9w5jhsw	239	13	with	with	IN
cord-260708-l9w5jhsw	239	14	a	a	DT
cord-260708-l9w5jhsw	239	15	5	5	CD
cord-260708-l9w5jhsw	239	16	'	'	''
cord-260708-l9w5jhsw	239	17	triphosphate	triphosphate	NN
cord-260708-l9w5jhsw	239	18	group	group	NN
cord-260708-l9w5jhsw	239	19	,	,	,
cord-260708-l9w5jhsw	239	20	such	such	JJ
cord-260708-l9w5jhsw	239	21	as	as	IN
cord-260708-l9w5jhsw	239	22	viral	viral	JJ
cord-260708-l9w5jhsw	239	23	vRNAs	vRNAs	.
cord-260708-l9w5jhsw	240	1	and	and	CC
cord-260708-l9w5jhsw	240	2	cRNAs	crna	NNS
cord-260708-l9w5jhsw	240	3	,	,	,
cord-260708-l9w5jhsw	240	4	while	while	IN
cord-260708-l9w5jhsw	240	5	MDA-5	MDA-5	NNP
cord-260708-l9w5jhsw	240	6	is	be	VBZ
cord-260708-l9w5jhsw	240	7	activated	activate	VBN
cord-260708-l9w5jhsw	240	8	by	by	IN
cord-260708-l9w5jhsw	240	9	binding	bind	VBG
cord-260708-l9w5jhsw	240	10	dsRNAs	dsRNAs	NNP
cord-260708-l9w5jhsw	240	11	[	[	-LRB-
cord-260708-l9w5jhsw	240	12	44	44	CD
cord-260708-l9w5jhsw	240	13	,	,	,
cord-260708-l9w5jhsw	240	14	86	86	CD
cord-260708-l9w5jhsw	240	15	,	,	,
cord-260708-l9w5jhsw	240	16	92	92	CD
cord-260708-l9w5jhsw	240	17	,	,	,
cord-260708-l9w5jhsw	240	18	128	128	CD
cord-260708-l9w5jhsw	240	19	]	]	-RRB-
cord-260708-l9w5jhsw	240	20	.	.	.
cord-260708-l9w5jhsw	241	1	Like	like	IN
cord-260708-l9w5jhsw	241	2	other	other	JJ
cord-260708-l9w5jhsw	241	3	negative	negative	JJ
cord-260708-l9w5jhsw	241	4	-	-	HYPH
cord-260708-l9w5jhsw	241	5	sense	sense	NN
cord-260708-l9w5jhsw	241	6	RNA	RNA	NNP
cord-260708-l9w5jhsw	241	7	viruses	virus	NNS
cord-260708-l9w5jhsw	241	8	,	,	,
cord-260708-l9w5jhsw	241	9	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	241	10	do	do	VBP
cord-260708-l9w5jhsw	241	11	not	not	RB
cord-260708-l9w5jhsw	241	12	produce	produce	VB
cord-260708-l9w5jhsw	241	13	detectable	detectable	JJ
cord-260708-l9w5jhsw	241	14	amounts	amount	NNS
cord-260708-l9w5jhsw	241	15	of	of	IN
cord-260708-l9w5jhsw	241	16	dsRNA	dsrna	NN
cord-260708-l9w5jhsw	241	17	during	during	IN
cord-260708-l9w5jhsw	241	18	replication	replication	NN
cord-260708-l9w5jhsw	241	19	[	[	-LRB-
cord-260708-l9w5jhsw	241	20	178	178	CD
cord-260708-l9w5jhsw	241	21	]	]	-RRB-
cord-260708-l9w5jhsw	241	22	and	and	CC
cord-260708-l9w5jhsw	241	23	hence	hence	RB
cord-260708-l9w5jhsw	241	24	avoid	avoid	VB
cord-260708-l9w5jhsw	241	25	activation	activation	NN
cord-260708-l9w5jhsw	241	26	of	of	IN
cord-260708-l9w5jhsw	241	27	a	a	DT
cord-260708-l9w5jhsw	241	28	number	number	NN
cord-260708-l9w5jhsw	241	29	of	of	IN
cord-260708-l9w5jhsw	241	30	dsRNA	dsrna	JJ
cord-260708-l9w5jhsw	241	31	-	-	HYPH
cord-260708-l9w5jhsw	241	32	sensitive	sensitive	JJ
cord-260708-l9w5jhsw	241	33	PRRs	prr	NNS
cord-260708-l9w5jhsw	241	34	(	(	-LRB-
cord-260708-l9w5jhsw	241	35	e.g.	e.g.	RB
cord-260708-l9w5jhsw	241	36	,	,	,
cord-260708-l9w5jhsw	241	37	MDA-5	MDA-5	NNP
cord-260708-l9w5jhsw	241	38	,	,	,
cord-260708-l9w5jhsw	241	39	TLR3	TLR3	NNP
cord-260708-l9w5jhsw	241	40	)	)	-RRB-
cord-260708-l9w5jhsw	241	41	and	and	CC
cord-260708-l9w5jhsw	241	42	dsRNA	dsrna	JJ
cord-260708-l9w5jhsw	241	43	-	-	HYPH
cord-260708-l9w5jhsw	241	44	dependent	dependent	JJ
cord-260708-l9w5jhsw	241	45	enzymes	enzyme	NNS
cord-260708-l9w5jhsw	241	46	(	(	-LRB-
cord-260708-l9w5jhsw	241	47	e.g.	e.g.	RB
cord-260708-l9w5jhsw	241	48	,	,	,
cord-260708-l9w5jhsw	241	49	dsRNA	dsrna	RB
cord-260708-l9w5jhsw	241	50	-	-	HYPH
cord-260708-l9w5jhsw	241	51	activated	activate	VBN
cord-260708-l9w5jhsw	241	52	protein	protein	NN
cord-260708-l9w5jhsw	241	53	kinase	kinase	NN
cord-260708-l9w5jhsw	241	54	R	r	NN
cord-260708-l9w5jhsw	241	55	[	[	-LRB-
cord-260708-l9w5jhsw	241	56	PKR	PKR	NNP
cord-260708-l9w5jhsw	241	57	]	]	-RRB-
cord-260708-l9w5jhsw	241	58	and	and	CC
cord-260708-l9w5jhsw	241	59	2'5'-oligoadenylate	2'5'-oligoadenylate	CD
cord-260708-l9w5jhsw	241	60	synthetase	synthetase	NN
cord-260708-l9w5jhsw	241	61	[	[	-LRB-
cord-260708-l9w5jhsw	241	62	2'5	2'5	CD
cord-260708-l9w5jhsw	241	63	'	'	''
cord-260708-l9w5jhsw	241	64	OAS	OAS	NNP
cord-260708-l9w5jhsw	241	65	]	]	-RRB-
cord-260708-l9w5jhsw	241	66	)	)	-RRB-
cord-260708-l9w5jhsw	241	67	.	.	.
cord-260708-l9w5jhsw	242	1	The	the	DT
cord-260708-l9w5jhsw	242	2	newly	newly	RB
cord-260708-l9w5jhsw	242	3	synthesised	synthesise	VBN
cord-260708-l9w5jhsw	242	4	vRNA	vrna	RP
cord-260708-l9w5jhsw	242	5	and	and	CC
cord-260708-l9w5jhsw	242	6	cRNA	cRNA	NNS
cord-260708-l9w5jhsw	242	7	of	of	IN
cord-260708-l9w5jhsw	242	8	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	242	9	,	,	,
cord-260708-l9w5jhsw	242	10	as	as	IN
cord-260708-l9w5jhsw	242	11	for	for	IN
cord-260708-l9w5jhsw	242	12	other	other	JJ
cord-260708-l9w5jhsw	242	13	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	242	14	,	,	,
cord-260708-l9w5jhsw	242	15	is	be	VBZ
cord-260708-l9w5jhsw	242	16	cotranscriptionally	cotranscriptionally	RB
cord-260708-l9w5jhsw	242	17	encapsidated	encapsidate	VBN
cord-260708-l9w5jhsw	242	18	by	by	IN
cord-260708-l9w5jhsw	242	19	the	the	DT
cord-260708-l9w5jhsw	242	20	N	N	NNP
cord-260708-l9w5jhsw	242	21	protein	protein	NN
cord-260708-l9w5jhsw	242	22	,	,	,
cord-260708-l9w5jhsw	242	23	minimising	minimise	VBG
cord-260708-l9w5jhsw	242	24	the	the	DT
cord-260708-l9w5jhsw	242	25	exposure	exposure	NN
cord-260708-l9w5jhsw	242	26	of	of	IN
cord-260708-l9w5jhsw	242	27	vRNAs	vrna	NNS
cord-260708-l9w5jhsw	242	28	and	and	CC
cord-260708-l9w5jhsw	242	29	preventing	prevent	VBG
cord-260708-l9w5jhsw	242	30	formation	formation	NN
cord-260708-l9w5jhsw	242	31	of	of	IN
cord-260708-l9w5jhsw	242	32	dsRNA	dsrna	NN
cord-260708-l9w5jhsw	242	33	intermediates	intermediate	NNS
cord-260708-l9w5jhsw	242	34	[	[	-LRB-
cord-260708-l9w5jhsw	242	35	127	127	CD
cord-260708-l9w5jhsw	242	36	,	,	,
cord-260708-l9w5jhsw	242	37	135	135	CD
cord-260708-l9w5jhsw	242	38	,	,	,
cord-260708-l9w5jhsw	242	39	173	173	CD
cord-260708-l9w5jhsw	242	40	]	]	-RRB-
cord-260708-l9w5jhsw	242	41	.	.	.
cord-260708-l9w5jhsw	243	1	It	-PRON-	PRP
cord-260708-l9w5jhsw	243	2	is	be	VBZ
cord-260708-l9w5jhsw	243	3	thought	think	VBN
cord-260708-l9w5jhsw	243	4	that	that	IN
cord-260708-l9w5jhsw	243	5	the	the	DT
cord-260708-l9w5jhsw	243	6	major	major	JJ
cord-260708-l9w5jhsw	243	7	sensor	sensor	NN
cord-260708-l9w5jhsw	243	8	for	for	IN
cord-260708-l9w5jhsw	243	9	bunyavirus	bunyavirus	NNP
cord-260708-l9w5jhsw	243	10	infection	infection	NN
cord-260708-l9w5jhsw	243	11	is	be	VBZ
cord-260708-l9w5jhsw	243	12	therefore	therefore	RB
cord-260708-l9w5jhsw	243	13	RIG	rig	NN
cord-260708-l9w5jhsw	243	14	-	-	HYPH
cord-260708-l9w5jhsw	243	15	I.	i.	NN
cord-260708-l9w5jhsw	243	16	5'triphosphate	5'triphosphate	CD
cord-260708-l9w5jhsw	243	17	groups	group	NNS
cord-260708-l9w5jhsw	243	18	are	be	VBP
cord-260708-l9w5jhsw	243	19	present	present	JJ
cord-260708-l9w5jhsw	243	20	on	on	IN
cord-260708-l9w5jhsw	243	21	RNA	RNA	NNP
cord-260708-l9w5jhsw	243	22	molecules	molecule	NNS
cord-260708-l9w5jhsw	243	23	generated	generate	VBN
cord-260708-l9w5jhsw	243	24	during	during	IN
cord-260708-l9w5jhsw	243	25	viral	viral	JJ
cord-260708-l9w5jhsw	243	26	replication	replication	NN
cord-260708-l9w5jhsw	243	27	but	but	CC
cord-260708-l9w5jhsw	243	28	are	be	VBP
cord-260708-l9w5jhsw	243	29	absent	absent	JJ
cord-260708-l9w5jhsw	243	30	on	on	IN
cord-260708-l9w5jhsw	243	31	cellular	cellular	JJ
cord-260708-l9w5jhsw	243	32	RNAs	rna	NNS
cord-260708-l9w5jhsw	243	33	,	,	,
cord-260708-l9w5jhsw	243	34	as	as	IN
cord-260708-l9w5jhsw	243	35	cellular	cellular	JJ
cord-260708-l9w5jhsw	243	36	mRNA	mRNA	NNP
cord-260708-l9w5jhsw	243	37	contains	contain	VBZ
cord-260708-l9w5jhsw	243	38	a	a	DT
cord-260708-l9w5jhsw	243	39	cap	cap	NN
cord-260708-l9w5jhsw	243	40	structure	structure	NN
cord-260708-l9w5jhsw	243	41	at	at	IN
cord-260708-l9w5jhsw	243	42	the	the	DT
cord-260708-l9w5jhsw	243	43	5	5	CD
cord-260708-l9w5jhsw	243	44	'	'	NN
cord-260708-l9w5jhsw	243	45	end	end	NN
cord-260708-l9w5jhsw	243	46	,	,	,
cord-260708-l9w5jhsw	243	47	and	and	CC
cord-260708-l9w5jhsw	243	48	the	the	DT
cord-260708-l9w5jhsw	243	49	transcription	transcription	NN
cord-260708-l9w5jhsw	243	50	products	product	NNS
cord-260708-l9w5jhsw	243	51	of	of	IN
cord-260708-l9w5jhsw	243	52	other	other	JJ
cord-260708-l9w5jhsw	243	53	cellular	cellular	JJ
cord-260708-l9w5jhsw	243	54	RNA	RNA	NNP
cord-260708-l9w5jhsw	243	55	polymerases	polymerase	NNS
cord-260708-l9w5jhsw	243	56	(	(	-LRB-
cord-260708-l9w5jhsw	243	57	RNA	RNA	NNP
cord-260708-l9w5jhsw	243	58	polymerases	polymerase	NNS
cord-260708-l9w5jhsw	243	59	I	-PRON-	PRP
cord-260708-l9w5jhsw	243	60	and	and	CC
cord-260708-l9w5jhsw	243	61	III	III	NNP
cord-260708-l9w5jhsw	243	62	)	)	-RRB-
cord-260708-l9w5jhsw	243	63	contain	contain	VBP
cord-260708-l9w5jhsw	243	64	a	a	DT
cord-260708-l9w5jhsw	243	65	monophosphate	monophosphate	NN
cord-260708-l9w5jhsw	243	66	at	at	IN
cord-260708-l9w5jhsw	243	67	the	the	DT
cord-260708-l9w5jhsw	243	68	5	5	CD
cord-260708-l9w5jhsw	243	69	'	'	NN
cord-260708-l9w5jhsw	243	70	end	end	NN
cord-260708-l9w5jhsw	243	71	.	.	.
cord-260708-l9w5jhsw	244	1	By	by	IN
cord-260708-l9w5jhsw	244	2	utilising	utilise	VBG
cord-260708-l9w5jhsw	244	3	capped	cap	VBN
cord-260708-l9w5jhsw	244	4	,	,	,
cord-260708-l9w5jhsw	244	5	short	short	JJ
cord-260708-l9w5jhsw	244	6	nucleotide	nucleotide	NN
cord-260708-l9w5jhsw	244	7	sequences	sequence	NNS
cord-260708-l9w5jhsw	244	8	snatched	snatch	VBN
cord-260708-l9w5jhsw	244	9	from	from	IN
cord-260708-l9w5jhsw	244	10	host	host	NN
cord-260708-l9w5jhsw	244	11	mRNA	mRNA	NNP
cord-260708-l9w5jhsw	244	12	to	to	TO
cord-260708-l9w5jhsw	244	13	initiate	initiate	VB
cord-260708-l9w5jhsw	244	14	viral	viral	JJ
cord-260708-l9w5jhsw	244	15	mRNA	mrna	NN
cord-260708-l9w5jhsw	244	16	transcription	transcription	NN
cord-260708-l9w5jhsw	244	17	[	[	-LRB-
cord-260708-l9w5jhsw	244	18	90	90	CD
cord-260708-l9w5jhsw	244	19	]	]	-RRB-
cord-260708-l9w5jhsw	244	20	,	,	,
cord-260708-l9w5jhsw	244	21	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	244	22	prevent	prevent	VBP
cord-260708-l9w5jhsw	244	23	recognition	recognition	NN
cord-260708-l9w5jhsw	244	24	of	of	IN
cord-260708-l9w5jhsw	244	25	viral	viral	JJ
cord-260708-l9w5jhsw	244	26	mRNA	mRNA	NNP
cord-260708-l9w5jhsw	244	27	by	by	IN
cord-260708-l9w5jhsw	244	28	PRRs	prr	NNS
cord-260708-l9w5jhsw	244	29	.	.	.
cord-260708-l9w5jhsw	245	1	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	245	2	further	further	RB
cord-260708-l9w5jhsw	245	3	avoids	avoid	VBZ
cord-260708-l9w5jhsw	245	4	activation	activation	NN
cord-260708-l9w5jhsw	245	5	of	of	IN
cord-260708-l9w5jhsw	245	6	RIG	rig	NN
cord-260708-l9w5jhsw	245	7	-	-	:
cord-260708-l9w5jhsw	245	8	I	-PRON-	PRP
cord-260708-l9w5jhsw	245	9	as	as	IN
cord-260708-l9w5jhsw	245	10	its	-PRON-	PRP$
cord-260708-l9w5jhsw	245	11	vRNA	vrna	JJ
cord-260708-l9w5jhsw	245	12	and	and	CC
cord-260708-l9w5jhsw	245	13	cRNA	cRNA	NNS
cord-260708-l9w5jhsw	245	14	have	have	VBP
cord-260708-l9w5jhsw	245	15	a	a	DT
cord-260708-l9w5jhsw	245	16	monophosphate	monophosphate	NN
cord-260708-l9w5jhsw	245	17	group	group	NN
cord-260708-l9w5jhsw	245	18	rather	rather	RB
cord-260708-l9w5jhsw	245	19	than	than	IN
cord-260708-l9w5jhsw	245	20	the	the	DT
cord-260708-l9w5jhsw	245	21	triphosphate	triphosphate	NN
cord-260708-l9w5jhsw	245	22	group	group	NN
cord-260708-l9w5jhsw	245	23	found	find	VBD
cord-260708-l9w5jhsw	245	24	at	at	IN
cord-260708-l9w5jhsw	245	25	the	the	DT
cord-260708-l9w5jhsw	245	26	5	5	CD
cord-260708-l9w5jhsw	245	27	'	'	NN
cord-260708-l9w5jhsw	245	28	end	end	NN
cord-260708-l9w5jhsw	245	29	of	of	IN
cord-260708-l9w5jhsw	245	30	most	most	JJS
cord-260708-l9w5jhsw	245	31	viral	viral	JJ
cord-260708-l9w5jhsw	245	32	RNAs	rna	NNS
cord-260708-l9w5jhsw	245	33	[	[	-LRB-
cord-260708-l9w5jhsw	245	34	78	78	CD
cord-260708-l9w5jhsw	245	35	]	]	-RRB-
cord-260708-l9w5jhsw	245	36	,	,	,
cord-260708-l9w5jhsw	245	37	though	though	IN
cord-260708-l9w5jhsw	245	38	the	the	DT
cord-260708-l9w5jhsw	245	39	mechanism	mechanism	NN
cord-260708-l9w5jhsw	245	40	of	of	IN
cord-260708-l9w5jhsw	245	41	5	5	CD
cord-260708-l9w5jhsw	245	42	'	'	POS
cord-260708-l9w5jhsw	245	43	monophosphate	monophosphate	NN
cord-260708-l9w5jhsw	245	44	generation	generation	NN
cord-260708-l9w5jhsw	245	45	during	during	IN
cord-260708-l9w5jhsw	245	46	replication	replication	NN
cord-260708-l9w5jhsw	245	47	of	of	IN
cord-260708-l9w5jhsw	245	48	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	245	49	remains	remain	VBZ
cord-260708-l9w5jhsw	245	50	unknown	unknown	JJ
cord-260708-l9w5jhsw	245	51	.	.	.
cord-260708-l9w5jhsw	246	1	Strategies	strategy	NNS
cord-260708-l9w5jhsw	246	2	to	to	TO
cord-260708-l9w5jhsw	246	3	generate	generate	VB
cord-260708-l9w5jhsw	246	4	5'monophosphates	5'monophosphates	CD
cord-260708-l9w5jhsw	246	5	on	on	IN
cord-260708-l9w5jhsw	246	6	viral	viral	JJ
cord-260708-l9w5jhsw	246	7	RNA	RNA	NNP
cord-260708-l9w5jhsw	246	8	have	have	VBP
cord-260708-l9w5jhsw	246	9	been	be	VBN
cord-260708-l9w5jhsw	246	10	shown	show	VBN
cord-260708-l9w5jhsw	246	11	for	for	IN
cord-260708-l9w5jhsw	246	12	other	other	JJ
cord-260708-l9w5jhsw	246	13	viruses	virus	NNS
cord-260708-l9w5jhsw	246	14	:	:	:
cord-260708-l9w5jhsw	246	15	HTNV	HTNV	NNP
cord-260708-l9w5jhsw	246	16	utilises	utilise	VBZ
cord-260708-l9w5jhsw	246	17	a	a	DT
cord-260708-l9w5jhsw	246	18	prime	prime	JJ
cord-260708-l9w5jhsw	246	19	-	-	HYPH
cord-260708-l9w5jhsw	246	20	and	and	CC
cord-260708-l9w5jhsw	246	21	-	-	HYPH
cord-260708-l9w5jhsw	246	22	realign	realign	VB
cord-260708-l9w5jhsw	246	23	mechanism	mechanism	NN
cord-260708-l9w5jhsw	246	24	to	to	TO
cord-260708-l9w5jhsw	246	25	generate	generate	VB
cord-260708-l9w5jhsw	246	26	5	5	CD
cord-260708-l9w5jhsw	246	27	'	'	''
cord-260708-l9w5jhsw	246	28	and	and	CC
cord-260708-l9w5jhsw	246	29	3	3	CD
cord-260708-l9w5jhsw	246	30	'	'	POS
cord-260708-l9w5jhsw	246	31	complementary	complementary	JJ
cord-260708-l9w5jhsw	246	32	ends	end	NNS
cord-260708-l9w5jhsw	246	33	,	,	,
cord-260708-l9w5jhsw	246	34	where	where	WRB
cord-260708-l9w5jhsw	246	35	a	a	DT
cord-260708-l9w5jhsw	246	36	viral	viral	JJ
cord-260708-l9w5jhsw	246	37	endonuclease	endonuclease	NN
cord-260708-l9w5jhsw	246	38	(	(	-LRB-
cord-260708-l9w5jhsw	246	39	which	which	WDT
cord-260708-l9w5jhsw	246	40	is	be	VBZ
cord-260708-l9w5jhsw	246	41	probably	probably	RB
cord-260708-l9w5jhsw	246	42	also	also	RB
cord-260708-l9w5jhsw	246	43	involved	involve	VBN
cord-260708-l9w5jhsw	246	44	in	in	IN
cord-260708-l9w5jhsw	246	45	cap	cap	NN
cord-260708-l9w5jhsw	246	46	-	-	HYPH
cord-260708-l9w5jhsw	246	47	snatching	snatching	NN
cord-260708-l9w5jhsw	246	48	)	)	-RRB-
cord-260708-l9w5jhsw	246	49	is	be	VBZ
cord-260708-l9w5jhsw	246	50	proposed	propose	VBN
cord-260708-l9w5jhsw	246	51	to	to	TO
cord-260708-l9w5jhsw	246	52	remove	remove	VB
cord-260708-l9w5jhsw	246	53	5'-terminal	5'-terminal	CD
cord-260708-l9w5jhsw	246	54	extensions	extension	NNS
cord-260708-l9w5jhsw	246	55	,	,	,
cord-260708-l9w5jhsw	246	56	leading	lead	VBG
cord-260708-l9w5jhsw	246	57	to	to	IN
cord-260708-l9w5jhsw	246	58	a	a	DT
cord-260708-l9w5jhsw	246	59	5	5	CD
cord-260708-l9w5jhsw	246	60	'	'	''
cord-260708-l9w5jhsw	246	61	monophosphate	monophosphate	NN
cord-260708-l9w5jhsw	246	62	on	on	IN
cord-260708-l9w5jhsw	246	63	the	the	DT
cord-260708-l9w5jhsw	246	64	final	final	JJ
cord-260708-l9w5jhsw	246	65	RNA	RNA	NNP
cord-260708-l9w5jhsw	246	66	[	[	-LRB-
cord-260708-l9w5jhsw	246	67	73	73	CD
cord-260708-l9w5jhsw	246	68	]	]	-RRB-
cord-260708-l9w5jhsw	246	69	.	.	.
cord-260708-l9w5jhsw	247	1	Interestingly	interestingly	RB
cord-260708-l9w5jhsw	247	2	,	,	,
cord-260708-l9w5jhsw	247	3	this	this	DT
cord-260708-l9w5jhsw	247	4	mechanism	mechanism	NN
cord-260708-l9w5jhsw	247	5	is	be	VBZ
cord-260708-l9w5jhsw	247	6	not	not	RB
cord-260708-l9w5jhsw	247	7	common	common	JJ
cord-260708-l9w5jhsw	247	8	to	to	IN
cord-260708-l9w5jhsw	247	9	all	all	DT
cord-260708-l9w5jhsw	247	10	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	247	11	,	,	,
cord-260708-l9w5jhsw	247	12	as	as	IN
cord-260708-l9w5jhsw	247	13	RVFV	RVFV	NNP
cord-260708-l9w5jhsw	247	14	was	be	VBD
cord-260708-l9w5jhsw	247	15	shown	show	VBN
cord-260708-l9w5jhsw	247	16	to	to	TO
cord-260708-l9w5jhsw	247	17	contain	contain	VB
cord-260708-l9w5jhsw	247	18	triphosphate	triphosphate	NN
cord-260708-l9w5jhsw	247	19	groups	group	NNS
cord-260708-l9w5jhsw	247	20	at	at	IN
cord-260708-l9w5jhsw	247	21	the	the	DT
cord-260708-l9w5jhsw	247	22	5	5	CD
cord-260708-l9w5jhsw	247	23	'	'	POS
cord-260708-l9w5jhsw	247	24	ends	end	NNS
cord-260708-l9w5jhsw	247	25	of	of	IN
cord-260708-l9w5jhsw	247	26	its	-PRON-	PRP$
cord-260708-l9w5jhsw	247	27	vRNAs	vrna	NNS
cord-260708-l9w5jhsw	247	28	,	,	,
cord-260708-l9w5jhsw	247	29	which	which	WDT
cord-260708-l9w5jhsw	247	30	can	can	MD
cord-260708-l9w5jhsw	247	31	activate	activate	VB
cord-260708-l9w5jhsw	247	32	IFNb	IFNb	NNS
cord-260708-l9w5jhsw	247	33	via	via	IN
cord-260708-l9w5jhsw	247	34	the	the	DT
cord-260708-l9w5jhsw	247	35	RIG	rig	NN
cord-260708-l9w5jhsw	247	36	-	-	:
cord-260708-l9w5jhsw	247	37	I	-PRON-	PRP
cord-260708-l9w5jhsw	247	38	pathway	pathway	VBP
cord-260708-l9w5jhsw	247	39	[	[	-LRB-
cord-260708-l9w5jhsw	247	40	78	78	CD
cord-260708-l9w5jhsw	247	41	]	]	-RRB-
cord-260708-l9w5jhsw	247	42	.	.	.
cord-260708-l9w5jhsw	248	1	It	-PRON-	PRP
cord-260708-l9w5jhsw	248	2	will	will	MD
cord-260708-l9w5jhsw	248	3	be	be	VB
cord-260708-l9w5jhsw	248	4	interesting	interesting	JJ
cord-260708-l9w5jhsw	248	5	to	to	TO
cord-260708-l9w5jhsw	248	6	see	see	VB
cord-260708-l9w5jhsw	248	7	if	if	IN
cord-260708-l9w5jhsw	248	8	other	other	JJ
cord-260708-l9w5jhsw	248	9	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	248	10	adopt	adopt	VBP
cord-260708-l9w5jhsw	248	11	the	the	DT
cord-260708-l9w5jhsw	248	12	RNA	RNA	NNP
cord-260708-l9w5jhsw	248	13	processing	processing	NN
cord-260708-l9w5jhsw	248	14	seen	see	VBN
cord-260708-l9w5jhsw	248	15	for	for	IN
cord-260708-l9w5jhsw	248	16	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	248	17	.	.	.
cord-260708-l9w5jhsw	249	1	It	-PRON-	PRP
cord-260708-l9w5jhsw	249	2	is	be	VBZ
cord-260708-l9w5jhsw	249	3	possible	possible	JJ
cord-260708-l9w5jhsw	249	4	that	that	IN
cord-260708-l9w5jhsw	249	5	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	249	6	that	that	WDT
cord-260708-l9w5jhsw	249	7	have	have	VBP
cord-260708-l9w5jhsw	249	8	developed	develop	VBN
cord-260708-l9w5jhsw	249	9	methods	method	NNS
cord-260708-l9w5jhsw	249	10	of	of	IN
cord-260708-l9w5jhsw	249	11	blocking	block	VBG
cord-260708-l9w5jhsw	249	12	the	the	DT
cord-260708-l9w5jhsw	249	13	RIG	rig	NN
cord-260708-l9w5jhsw	249	14	-	-	HYPH
cord-260708-l9w5jhsw	249	15	I	-PRON-	PRP
cord-260708-l9w5jhsw	249	16	-	-	HYPH
cord-260708-l9w5jhsw	249	17	activated	activate	VBN
cord-260708-l9w5jhsw	249	18	pathway	pathway	NN
cord-260708-l9w5jhsw	249	19	(	(	-LRB-
cord-260708-l9w5jhsw	249	20	e.g.	e.g.	RB
cord-260708-l9w5jhsw	249	21	,	,	,
cord-260708-l9w5jhsw	249	22	by	by	IN
cord-260708-l9w5jhsw	249	23	the	the	DT
cord-260708-l9w5jhsw	249	24	activities	activity	NNS
cord-260708-l9w5jhsw	249	25	of	of	IN
cord-260708-l9w5jhsw	249	26	a	a	DT
cord-260708-l9w5jhsw	249	27	nonstructural	nonstructural	JJ
cord-260708-l9w5jhsw	249	28	protein	protein	NN
cord-260708-l9w5jhsw	249	29	such	such	JJ
cord-260708-l9w5jhsw	249	30	as	as	IN
cord-260708-l9w5jhsw	249	31	the	the	DT
cord-260708-l9w5jhsw	249	32	phlebovirus	phlebovirus	NNP
cord-260708-l9w5jhsw	249	33	NSs	NSs	NNP
cord-260708-l9w5jhsw	249	34	protein	protein	NNP
cord-260708-l9w5jhsw	249	35	)	)	-RRB-
cord-260708-l9w5jhsw	249	36	can	can	MD
cord-260708-l9w5jhsw	249	37	have	have	VB
cord-260708-l9w5jhsw	249	38	triphosphates	triphosphate	NNS
cord-260708-l9w5jhsw	249	39	at	at	IN
cord-260708-l9w5jhsw	249	40	the	the	DT
cord-260708-l9w5jhsw	249	41	5	5	CD
cord-260708-l9w5jhsw	249	42	'	'	NN
cord-260708-l9w5jhsw	249	43	end	end	NN
cord-260708-l9w5jhsw	249	44	of	of	IN
cord-260708-l9w5jhsw	249	45	their	-PRON-	PRP$
cord-260708-l9w5jhsw	249	46	vRNAs	vrna	NNS
cord-260708-l9w5jhsw	249	47	while	while	IN
cord-260708-l9w5jhsw	249	48	viruses	virus	NNS
cord-260708-l9w5jhsw	249	49	that	that	WDT
cord-260708-l9w5jhsw	249	50	do	do	VBP
cord-260708-l9w5jhsw	249	51	not	not	RB
cord-260708-l9w5jhsw	249	52	have	have	VB
cord-260708-l9w5jhsw	249	53	an	an	DT
cord-260708-l9w5jhsw	249	54	NSs	NSs	NNP
cord-260708-l9w5jhsw	249	55	activity	activity	NN
cord-260708-l9w5jhsw	249	56	must	must	MD
cord-260708-l9w5jhsw	249	57	generate	generate	VB
cord-260708-l9w5jhsw	249	58	monophosphates	monophosphate	NNS
cord-260708-l9w5jhsw	249	59	to	to	TO
cord-260708-l9w5jhsw	249	60	avoid	avoid	VB
cord-260708-l9w5jhsw	249	61	activating	activate	VBG
cord-260708-l9w5jhsw	249	62	the	the	DT
cord-260708-l9w5jhsw	249	63	RIG	rig	NN
cord-260708-l9w5jhsw	249	64	-	-	:
cord-260708-l9w5jhsw	249	65	I	-PRON-	PRP
cord-260708-l9w5jhsw	249	66	pathway	pathway	VBP
cord-260708-l9w5jhsw	249	67	in	in	IN
cord-260708-l9w5jhsw	249	68	the	the	DT
cord-260708-l9w5jhsw	249	69	first	first	JJ
cord-260708-l9w5jhsw	249	70	place	place	NN
cord-260708-l9w5jhsw	249	71	[	[	-LRB-
cord-260708-l9w5jhsw	249	72	18	18	CD
cord-260708-l9w5jhsw	249	73	,	,	,
cord-260708-l9w5jhsw	249	74	19	19	CD
cord-260708-l9w5jhsw	249	75	,	,	,
cord-260708-l9w5jhsw	249	76	23	23	CD
cord-260708-l9w5jhsw	249	77	,	,	,
cord-260708-l9w5jhsw	249	78	73	73	CD
cord-260708-l9w5jhsw	249	79	]	]	-RRB-
cord-260708-l9w5jhsw	249	80	.	.	.
cord-260708-l9w5jhsw	250	1	Ubiquitin	Ubiquitin	NNP
cord-260708-l9w5jhsw	250	2	and	and	CC
cord-260708-l9w5jhsw	250	3	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	250	4	-	-	HYPH
cord-260708-l9w5jhsw	250	5	like	like	JJ
cord-260708-l9w5jhsw	250	6	molecules	molecule	NNS
cord-260708-l9w5jhsw	250	7	play	play	VBP
cord-260708-l9w5jhsw	250	8	important	important	JJ
cord-260708-l9w5jhsw	250	9	roles	role	NNS
cord-260708-l9w5jhsw	250	10	in	in	IN
cord-260708-l9w5jhsw	250	11	the	the	DT
cord-260708-l9w5jhsw	250	12	initiation	initiation	NN
cord-260708-l9w5jhsw	250	13	and	and	CC
cord-260708-l9w5jhsw	250	14	maintenance	maintenance	NN
cord-260708-l9w5jhsw	250	15	of	of	IN
cord-260708-l9w5jhsw	250	16	immune	immune	JJ
cord-260708-l9w5jhsw	250	17	response	response	NN
cord-260708-l9w5jhsw	250	18	.	.	.
cord-260708-l9w5jhsw	251	1	For	for	IN
cord-260708-l9w5jhsw	251	2	example	example	NN
cord-260708-l9w5jhsw	251	3	,	,	,
cord-260708-l9w5jhsw	251	4	they	-PRON-	PRP
cord-260708-l9w5jhsw	251	5	are	be	VBP
cord-260708-l9w5jhsw	251	6	essential	essential	JJ
cord-260708-l9w5jhsw	251	7	for	for	IN
cord-260708-l9w5jhsw	251	8	the	the	DT
cord-260708-l9w5jhsw	251	9	action	action	NN
cord-260708-l9w5jhsw	251	10	of	of	IN
cord-260708-l9w5jhsw	251	11	cytokines	cytokine	NNS
cord-260708-l9w5jhsw	251	12	such	such	JJ
cord-260708-l9w5jhsw	251	13	as	as	IN
cord-260708-l9w5jhsw	251	14	IFNa	IFNa	NNS
cord-260708-l9w5jhsw	251	15	/	/	SYM
cord-260708-l9w5jhsw	251	16	b	b	NN
cord-260708-l9w5jhsw	251	17	and	and	CC
cord-260708-l9w5jhsw	251	18	tumour	tumour	NN
cord-260708-l9w5jhsw	251	19	necrosis	necrosis	NN
cord-260708-l9w5jhsw	251	20	factor	factor	NN
cord-260708-l9w5jhsw	251	21	alpha	alpha	NN
cord-260708-l9w5jhsw	251	22	(	(	-LRB-
cord-260708-l9w5jhsw	251	23	TNFa	TNFa	NNP
cord-260708-l9w5jhsw	251	24	)	)	-RRB-
cord-260708-l9w5jhsw	251	25	(	(	-LRB-
cord-260708-l9w5jhsw	251	26	reviewed	review	VBN
cord-260708-l9w5jhsw	251	27	in	in	IN
cord-260708-l9w5jhsw	251	28	ref	ref	NN
cord-260708-l9w5jhsw	251	29	.	.	.
cord-260708-l9w5jhsw	252	1	[	[	-LRB-
cord-260708-l9w5jhsw	252	2	95	95	CD
cord-260708-l9w5jhsw	252	3	]	]	-RRB-
cord-260708-l9w5jhsw	252	4	)	)	-RRB-
cord-260708-l9w5jhsw	252	5	.	.	.
cord-260708-l9w5jhsw	253	1	Ubiquitination	Ubiquitination	NNP
cord-260708-l9w5jhsw	253	2	allows	allow	VBZ
cord-260708-l9w5jhsw	253	3	for	for	IN
cord-260708-l9w5jhsw	253	4	the	the	DT
cord-260708-l9w5jhsw	253	5	activation	activation	NN
cord-260708-l9w5jhsw	253	6	of	of	IN
cord-260708-l9w5jhsw	253	7	nuclear	nuclear	JJ
cord-260708-l9w5jhsw	253	8	factor	factor	NN
cord-260708-l9w5jhsw	253	9	kappa	kappa	NN
cord-260708-l9w5jhsw	253	10	B	B	NNP
cord-260708-l9w5jhsw	253	11	(	(	-LRB-
cord-260708-l9w5jhsw	253	12	NF	NF	NNP
cord-260708-l9w5jhsw	253	13	-	-	HYPH
cord-260708-l9w5jhsw	253	14	jB	jB	NNP
cord-260708-l9w5jhsw	253	15	)	)	-RRB-
cord-260708-l9w5jhsw	253	16	by	by	IN
cord-260708-l9w5jhsw	253	17	targeting	target	VBG
cord-260708-l9w5jhsw	253	18	the	the	DT
cord-260708-l9w5jhsw	253	19	inhibitor	inhibitor	NN
cord-260708-l9w5jhsw	253	20	of	of	IN
cord-260708-l9w5jhsw	253	21	NF	nf	NN
cord-260708-l9w5jhsw	253	22	-	-	HYPH
cord-260708-l9w5jhsw	253	23	jB	jb	XX
cord-260708-l9w5jhsw	254	1	(	(	-LRB-
cord-260708-l9w5jhsw	254	2	I	i	NN
cord-260708-l9w5jhsw	254	3	-	-	HYPH
cord-260708-l9w5jhsw	254	4	jB	jB	NNP
cord-260708-l9w5jhsw	254	5	)	)	-RRB-
cord-260708-l9w5jhsw	255	1	for	for	IN
cord-260708-l9w5jhsw	255	2	degradation	degradation	NN
cord-260708-l9w5jhsw	255	3	[	[	-LRB-
cord-260708-l9w5jhsw	255	4	163	163	CD
cord-260708-l9w5jhsw	255	5	]	]	-RRB-
cord-260708-l9w5jhsw	255	6	.	.	.
cord-260708-l9w5jhsw	256	1	K63-linked	k63-linked	JJ
cord-260708-l9w5jhsw	256	2	ubiquitination	ubiquitination	NN
cord-260708-l9w5jhsw	256	3	activates	activate	VBZ
cord-260708-l9w5jhsw	256	4	several	several	JJ
cord-260708-l9w5jhsw	256	5	molecules	molecule	NNS
cord-260708-l9w5jhsw	256	6	of	of	IN
cord-260708-l9w5jhsw	256	7	the	the	DT
cord-260708-l9w5jhsw	256	8	IFNb	IFNb	NNP
cord-260708-l9w5jhsw	256	9	induction	induction	NN
cord-260708-l9w5jhsw	256	10	pathway	pathway	NN
cord-260708-l9w5jhsw	256	11	,	,	,
cord-260708-l9w5jhsw	256	12	including	include	VBG
cord-260708-l9w5jhsw	256	13	RIG	rig	NN
cord-260708-l9w5jhsw	256	14	-	-	HYPH
cord-260708-l9w5jhsw	256	15	I	i	NN
cord-260708-l9w5jhsw	256	16	,	,	,
cord-260708-l9w5jhsw	256	17	mitochondrial	mitochondrial	JJ
cord-260708-l9w5jhsw	256	18	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	256	19	signalling	signal	VBG
cord-260708-l9w5jhsw	256	20	protein	protein	NN
cord-260708-l9w5jhsw	256	21	(	(	-LRB-
cord-260708-l9w5jhsw	256	22	MAVS	MAVS	NNP
cord-260708-l9w5jhsw	256	23	)	)	-RRB-
cord-260708-l9w5jhsw	256	24	,	,	,
cord-260708-l9w5jhsw	256	25	TANK	tank	NN
cord-260708-l9w5jhsw	256	26	-	-	HYPH
cord-260708-l9w5jhsw	256	27	binding	bind	VBG
cord-260708-l9w5jhsw	256	28	kinase-1	kinase-1	NNP
cord-260708-l9w5jhsw	256	29	(	(	-LRB-
cord-260708-l9w5jhsw	256	30	TBK1	TBK1	NNP
cord-260708-l9w5jhsw	256	31	)	)	-RRB-
cord-260708-l9w5jhsw	256	32	,	,	,
cord-260708-l9w5jhsw	256	33	IjB	ijb	NN
cord-260708-l9w5jhsw	256	34	kinase	kinase	NN
cord-260708-l9w5jhsw	256	35	-	-	HYPH
cord-260708-l9w5jhsw	256	36	e	e	NN
cord-260708-l9w5jhsw	256	37	(	(	-LRB-
cord-260708-l9w5jhsw	256	38	IKK	IKK	NNP
cord-260708-l9w5jhsw	256	39	-	-	HYPH
cord-260708-l9w5jhsw	256	40	e	e	NNP
cord-260708-l9w5jhsw	256	41	)	)	-RRB-
cord-260708-l9w5jhsw	256	42	,	,	,
cord-260708-l9w5jhsw	256	43	tumour	tumour	NN
cord-260708-l9w5jhsw	256	44	necrosis	necrosis	NN
cord-260708-l9w5jhsw	256	45	factor	factor	NN
cord-260708-l9w5jhsw	256	46	receptor	receptor	NN
cord-260708-l9w5jhsw	256	47	-	-	HYPH
cord-260708-l9w5jhsw	256	48	associated	associate	VBN
cord-260708-l9w5jhsw	256	49	factor	factor	NN
cord-260708-l9w5jhsw	256	50	3	3	CD
cord-260708-l9w5jhsw	256	51	(	(	-LRB-
cord-260708-l9w5jhsw	256	52	TRAF3	traf3	NN
cord-260708-l9w5jhsw	256	53	)	)	-RRB-
cord-260708-l9w5jhsw	257	1	and	and	CC
cord-260708-l9w5jhsw	257	2	TRAF6	TRAF6	NNP
cord-260708-l9w5jhsw	257	3	[	[	-LRB-
cord-260708-l9w5jhsw	257	4	70	70	CD
cord-260708-l9w5jhsw	257	5	,	,	,
cord-260708-l9w5jhsw	257	6	125	125	CD
cord-260708-l9w5jhsw	257	7	,	,	,
cord-260708-l9w5jhsw	257	8	126	126	CD
cord-260708-l9w5jhsw	257	9	,	,	,
cord-260708-l9w5jhsw	257	10	166	166	CD
cord-260708-l9w5jhsw	257	11	]	]	-RRB-
cord-260708-l9w5jhsw	257	12	.	.	.
cord-260708-l9w5jhsw	258	1	In	in	IN
cord-260708-l9w5jhsw	258	2	addition	addition	NN
cord-260708-l9w5jhsw	258	3	to	to	IN
cord-260708-l9w5jhsw	258	4	modulation	modulation	NN
cord-260708-l9w5jhsw	258	5	of	of	IN
cord-260708-l9w5jhsw	258	6	the	the	DT
cord-260708-l9w5jhsw	258	7	innate	innate	JJ
cord-260708-l9w5jhsw	258	8	immune	immune	JJ
cord-260708-l9w5jhsw	258	9	signalling	signalling	NN
cord-260708-l9w5jhsw	258	10	,	,	,
cord-260708-l9w5jhsw	258	11	ubiquitination	ubiquitination	NN
cord-260708-l9w5jhsw	258	12	also	also	RB
cord-260708-l9w5jhsw	258	13	plays	play	VBZ
cord-260708-l9w5jhsw	258	14	an	an	DT
cord-260708-l9w5jhsw	258	15	important	important	JJ
cord-260708-l9w5jhsw	258	16	role	role	NN
cord-260708-l9w5jhsw	258	17	in	in	IN
cord-260708-l9w5jhsw	258	18	antigen	antigen	NN
cord-260708-l9w5jhsw	258	19	presentation	presentation	NN
cord-260708-l9w5jhsw	258	20	by	by	IN
cord-260708-l9w5jhsw	258	21	major	major	JJ
cord-260708-l9w5jhsw	258	22	histocompatibility	histocompatibility	NN
cord-260708-l9w5jhsw	258	23	complex	complex	NN
cord-260708-l9w5jhsw	258	24	(	(	-LRB-
cord-260708-l9w5jhsw	258	25	MHC	MHC	NNP
cord-260708-l9w5jhsw	258	26	)	)	-RRB-
cord-260708-l9w5jhsw	258	27	class	class	NN
cord-260708-l9w5jhsw	258	28	I	i	NN
cord-260708-l9w5jhsw	258	29	and	and	CC
cord-260708-l9w5jhsw	258	30	II	II	NNP
cord-260708-l9w5jhsw	258	31	proteins	protein	NNS
cord-260708-l9w5jhsw	258	32	[	[	-LRB-
cord-260708-l9w5jhsw	258	33	152	152	CD
cord-260708-l9w5jhsw	258	34	]	]	-RRB-
cord-260708-l9w5jhsw	258	35	.	.	.
cord-260708-l9w5jhsw	259	1	ISG15	ISG15	NNP
cord-260708-l9w5jhsw	259	2	is	be	VBZ
cord-260708-l9w5jhsw	259	3	an	an	DT
cord-260708-l9w5jhsw	259	4	IFNinduced	ifninduced	JJ
cord-260708-l9w5jhsw	259	5	15-kDa	15-kda	CD
cord-260708-l9w5jhsw	259	6	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	259	7	-	-	HYPH
cord-260708-l9w5jhsw	259	8	like	like	JJ
cord-260708-l9w5jhsw	259	9	molecule	molecule	NN
cord-260708-l9w5jhsw	259	10	that	that	WDT
cord-260708-l9w5jhsw	259	11	is	be	VBZ
cord-260708-l9w5jhsw	259	12	composed	compose	VBN
cord-260708-l9w5jhsw	259	13	of	of	IN
cord-260708-l9w5jhsw	259	14	two	two	CD
cord-260708-l9w5jhsw	259	15	-	-	HYPH
cord-260708-l9w5jhsw	259	16	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	259	17	-	-	HYPH
cord-260708-l9w5jhsw	259	18	like	like	JJ
cord-260708-l9w5jhsw	259	19	domains	domain	NNS
cord-260708-l9w5jhsw	259	20	[	[	-LRB-
cord-260708-l9w5jhsw	259	21	20	20	CD
cord-260708-l9w5jhsw	259	22	,	,	,
cord-260708-l9w5jhsw	259	23	117	117	CD
cord-260708-l9w5jhsw	259	24	]	]	-RRB-
cord-260708-l9w5jhsw	259	25	.	.	.
cord-260708-l9w5jhsw	260	1	Although	although	IN
cord-260708-l9w5jhsw	260	2	the	the	DT
cord-260708-l9w5jhsw	260	3	precise	precise	JJ
cord-260708-l9w5jhsw	260	4	role	role	NN
cord-260708-l9w5jhsw	260	5	of	of	IN
cord-260708-l9w5jhsw	260	6	ISG15	isg15	NN
cord-260708-l9w5jhsw	260	7	in	in	IN
cord-260708-l9w5jhsw	260	8	modulation	modulation	NN
cord-260708-l9w5jhsw	260	9	of	of	IN
cord-260708-l9w5jhsw	260	10	protein	protein	NN
cord-260708-l9w5jhsw	260	11	function	function	NN
cord-260708-l9w5jhsw	260	12	is	be	VBZ
cord-260708-l9w5jhsw	260	13	unknown	unknown	JJ
cord-260708-l9w5jhsw	260	14	,	,	,
cord-260708-l9w5jhsw	260	15	conjugation	conjugation	NN
cord-260708-l9w5jhsw	260	16	by	by	IN
cord-260708-l9w5jhsw	260	17	ISG15	ISG15	NNP
cord-260708-l9w5jhsw	260	18	is	be	VBZ
cord-260708-l9w5jhsw	260	19	also	also	RB
cord-260708-l9w5jhsw	260	20	known	know	VBN
cord-260708-l9w5jhsw	260	21	to	to	TO
cord-260708-l9w5jhsw	260	22	modify	modify	VB
cord-260708-l9w5jhsw	260	23	hundreds	hundred	NNS
cord-260708-l9w5jhsw	260	24	of	of	IN
cord-260708-l9w5jhsw	260	25	cellular	cellular	JJ
cord-260708-l9w5jhsw	260	26	proteins	protein	NNS
cord-260708-l9w5jhsw	260	27	,	,	,
cord-260708-l9w5jhsw	260	28	including	include	VBG
cord-260708-l9w5jhsw	260	29	several	several	JJ
cord-260708-l9w5jhsw	260	30	of	of	IN
cord-260708-l9w5jhsw	260	31	those	those	DT
cord-260708-l9w5jhsw	260	32	involved	involve	VBN
cord-260708-l9w5jhsw	260	33	in	in	IN
cord-260708-l9w5jhsw	260	34	the	the	DT
cord-260708-l9w5jhsw	260	35	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	260	36	response	response	NN
cord-260708-l9w5jhsw	260	37	,	,	,
cord-260708-l9w5jhsw	260	38	e.g.	e.g.	RB
cord-260708-l9w5jhsw	260	39	,	,	,
cord-260708-l9w5jhsw	260	40	PKR	PKR	NNP
cord-260708-l9w5jhsw	260	41	,	,	,
cord-260708-l9w5jhsw	260	42	MxA	mxa	NN
cord-260708-l9w5jhsw	260	43	,	,	,
cord-260708-l9w5jhsw	260	44	STAT1	stat1	XX
cord-260708-l9w5jhsw	260	45	,	,	,
cord-260708-l9w5jhsw	260	46	RIG	rig	NN
cord-260708-l9w5jhsw	260	47	-	-	:
cord-260708-l9w5jhsw	260	48	I	I	NNP
cord-260708-l9w5jhsw	260	49	,	,	,
cord-260708-l9w5jhsw	260	50	Janus	Janus	NNP
cord-260708-l9w5jhsw	260	51	kinase	kinase	VBD
cord-260708-l9w5jhsw	260	52	1	1	CD
cord-260708-l9w5jhsw	260	53	(	(	-LRB-
cord-260708-l9w5jhsw	260	54	JAK1	JAK1	NNP
cord-260708-l9w5jhsw	260	55	)	)	-RRB-
cord-260708-l9w5jhsw	260	56	,	,	,
cord-260708-l9w5jhsw	260	57	and	and	CC
cord-260708-l9w5jhsw	260	58	IRF-3	IRF-3	NNP
cord-260708-l9w5jhsw	260	59	[	[	-LRB-
cord-260708-l9w5jhsw	260	60	75	75	CD
cord-260708-l9w5jhsw	260	61	,	,	,
cord-260708-l9w5jhsw	260	62	104	104	CD
cord-260708-l9w5jhsw	260	63	,	,	,
cord-260708-l9w5jhsw	260	64	138	138	CD
cord-260708-l9w5jhsw	260	65	,	,	,
cord-260708-l9w5jhsw	260	66	192	192	CD
cord-260708-l9w5jhsw	260	67	]	]	-RRB-
cord-260708-l9w5jhsw	260	68	.	.	.
cord-260708-l9w5jhsw	261	1	Both	both	CC
cord-260708-l9w5jhsw	261	2	Ub	Ub	NNP
cord-260708-l9w5jhsw	261	3	and	and	CC
cord-260708-l9w5jhsw	261	4	ISG15	isg15	NN
cord-260708-l9w5jhsw	261	5	are	be	VBP
cord-260708-l9w5jhsw	261	6	synthesised	synthesise	VBN
cord-260708-l9w5jhsw	261	7	as	as	IN
cord-260708-l9w5jhsw	261	8	precursors	precursor	NNS
cord-260708-l9w5jhsw	261	9	,	,	,
cord-260708-l9w5jhsw	261	10	which	which	WDT
cord-260708-l9w5jhsw	261	11	are	be	VBP
cord-260708-l9w5jhsw	261	12	cleaved	cleave	VBN
cord-260708-l9w5jhsw	261	13	in	in	IN
cord-260708-l9w5jhsw	261	14	order	order	NN
cord-260708-l9w5jhsw	261	15	to	to	TO
cord-260708-l9w5jhsw	261	16	expose	expose	VB
cord-260708-l9w5jhsw	261	17	the	the	DT
cord-260708-l9w5jhsw	261	18	conjugation	conjugation	NN
cord-260708-l9w5jhsw	261	19	sequence	sequence	NN
cord-260708-l9w5jhsw	261	20	(	(	-LRB-
cord-260708-l9w5jhsw	261	21	LRLRGG	LRLRGG	NNP
cord-260708-l9w5jhsw	261	22	)	)	-RRB-
cord-260708-l9w5jhsw	261	23	by	by	IN
cord-260708-l9w5jhsw	261	24	which	which	WDT
cord-260708-l9w5jhsw	261	25	they	-PRON-	PRP
cord-260708-l9w5jhsw	261	26	are	be	VBP
cord-260708-l9w5jhsw	261	27	attached	attach	VBN
cord-260708-l9w5jhsw	261	28	to	to	IN
cord-260708-l9w5jhsw	261	29	other	other	JJ
cord-260708-l9w5jhsw	261	30	proteins	protein	NNS
cord-260708-l9w5jhsw	261	31	.	.	.
cord-260708-l9w5jhsw	262	1	The	the	DT
cord-260708-l9w5jhsw	262	2	conjugation	conjugation	NN
cord-260708-l9w5jhsw	262	3	is	be	VBZ
cord-260708-l9w5jhsw	262	4	mediated	mediate	VBN
cord-260708-l9w5jhsw	262	5	by	by	IN
cord-260708-l9w5jhsw	262	6	a	a	DT
cord-260708-l9w5jhsw	262	7	sequence	sequence	NN
cord-260708-l9w5jhsw	262	8	involving	involve	VBG
cord-260708-l9w5jhsw	262	9	activating	activate	VBG
cord-260708-l9w5jhsw	262	10	enzymes	enzyme	NNS
cord-260708-l9w5jhsw	262	11	(	(	-LRB-
cord-260708-l9w5jhsw	262	12	E1	E1	NNP
cord-260708-l9w5jhsw	262	13	)	)	-RRB-
cord-260708-l9w5jhsw	262	14	,	,	,
cord-260708-l9w5jhsw	262	15	conjugating	conjugate	VBG
cord-260708-l9w5jhsw	262	16	enzymes	enzyme	NNS
cord-260708-l9w5jhsw	262	17	(	(	-LRB-
cord-260708-l9w5jhsw	262	18	E2	E2	NNP
cord-260708-l9w5jhsw	262	19	)	)	-RRB-
cord-260708-l9w5jhsw	262	20	and	and	CC
cord-260708-l9w5jhsw	262	21	protein	protein	NN
cord-260708-l9w5jhsw	262	22	ligases	ligase	NNS
cord-260708-l9w5jhsw	262	23	(	(	-LRB-
cord-260708-l9w5jhsw	262	24	E3	E3	NNP
cord-260708-l9w5jhsw	262	25	)	)	-RRB-
cord-260708-l9w5jhsw	262	26	[	[	-LRB-
cord-260708-l9w5jhsw	262	27	157	157	CD
cord-260708-l9w5jhsw	262	28	,	,	,
cord-260708-l9w5jhsw	262	29	180	180	CD
cord-260708-l9w5jhsw	262	30	,	,	,
cord-260708-l9w5jhsw	262	31	191	191	CD
cord-260708-l9w5jhsw	262	32	]	]	-RRB-
cord-260708-l9w5jhsw	262	33	(	(	-LRB-
cord-260708-l9w5jhsw	262	34	reviewed	review	VBN
cord-260708-l9w5jhsw	262	35	in	in	IN
cord-260708-l9w5jhsw	262	36	ref	ref	NN
cord-260708-l9w5jhsw	262	37	.	.	.
cord-260708-l9w5jhsw	263	1	[	[	-LRB-
cord-260708-l9w5jhsw	263	2	169	169	CD
cord-260708-l9w5jhsw	263	3	]	]	-RRB-
cord-260708-l9w5jhsw	263	4	)	)	-RRB-
cord-260708-l9w5jhsw	263	5	.	.	.
cord-260708-l9w5jhsw	264	1	Removal	removal	NN
cord-260708-l9w5jhsw	264	2	of	of	IN
cord-260708-l9w5jhsw	264	3	these	these	DT
cord-260708-l9w5jhsw	264	4	conjugated	conjugate	VBN
cord-260708-l9w5jhsw	264	5	proteins	protein	NNS
cord-260708-l9w5jhsw	264	6	is	be	VBZ
cord-260708-l9w5jhsw	264	7	carried	carry	VBN
cord-260708-l9w5jhsw	264	8	out	out	RP
cord-260708-l9w5jhsw	264	9	by	by	IN
cord-260708-l9w5jhsw	264	10	cellular	cellular	JJ
cord-260708-l9w5jhsw	264	11	deubiquitinating	deubiquitinating	NN
cord-260708-l9w5jhsw	264	12	enzymes	enzyme	NNS
cord-260708-l9w5jhsw	264	13	and	and	CC
cord-260708-l9w5jhsw	264	14	deISGylating	deisgylate	VBG
cord-260708-l9w5jhsw	264	15	enzymes	enzyme	NNS
cord-260708-l9w5jhsw	264	16	,	,	,
cord-260708-l9w5jhsw	264	17	which	which	WDT
cord-260708-l9w5jhsw	264	18	have	have	VBP
cord-260708-l9w5jhsw	264	19	roles	role	NNS
cord-260708-l9w5jhsw	264	20	,	,	,
cord-260708-l9w5jhsw	264	21	as	as	IN
cord-260708-l9w5jhsw	264	22	expected	expect	VBN
cord-260708-l9w5jhsw	264	23	,	,	,
cord-260708-l9w5jhsw	264	24	in	in	IN
cord-260708-l9w5jhsw	264	25	negative	negative	JJ
cord-260708-l9w5jhsw	264	26	feedback	feedback	NN
cord-260708-l9w5jhsw	264	27	regulation	regulation	NN
cord-260708-l9w5jhsw	264	28	of	of	IN
cord-260708-l9w5jhsw	264	29	IFN	IFN	NNP
cord-260708-l9w5jhsw	264	30	induction	induction	NN
cord-260708-l9w5jhsw	264	31	and	and	CC
cord-260708-l9w5jhsw	264	32	action	action	NN
cord-260708-l9w5jhsw	264	33	[	[	-LRB-
cord-260708-l9w5jhsw	264	34	93	93	CD
cord-260708-l9w5jhsw	264	35	,	,	,
cord-260708-l9w5jhsw	264	36	99	99	CD
cord-260708-l9w5jhsw	264	37	]	]	-RRB-
cord-260708-l9w5jhsw	264	38	.	.	.
cord-260708-l9w5jhsw	265	1	As	as	IN
cord-260708-l9w5jhsw	265	2	described	describe	VBN
cord-260708-l9w5jhsw	265	3	in	in	IN
cord-260708-l9w5jhsw	265	4	the	the	DT
cord-260708-l9w5jhsw	265	5	discussion	discussion	NN
cord-260708-l9w5jhsw	265	6	of	of	IN
cord-260708-l9w5jhsw	265	7	the	the	DT
cord-260708-l9w5jhsw	265	8	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	265	9	L	L	NNP
cord-260708-l9w5jhsw	265	10	protein	protein	NN
cord-260708-l9w5jhsw	265	11	,	,	,
cord-260708-l9w5jhsw	265	12	the	the	DT
cord-260708-l9w5jhsw	265	13	N	n	NN
cord-260708-l9w5jhsw	265	14	-	-	HYPH
cord-260708-l9w5jhsw	265	15	terminus	terminus	NN
cord-260708-l9w5jhsw	265	16	of	of	IN
cord-260708-l9w5jhsw	265	17	these	these	DT
cord-260708-l9w5jhsw	265	18	proteins	protein	NNS
cord-260708-l9w5jhsw	265	19	contains	contain	VBZ
cord-260708-l9w5jhsw	265	20	an	an	DT
cord-260708-l9w5jhsw	265	21	OTU	OTU	NNP
cord-260708-l9w5jhsw	265	22	proteaselike	proteaselike	JJ
cord-260708-l9w5jhsw	265	23	domain	domain	NN
cord-260708-l9w5jhsw	265	24	[	[	-LRB-
cord-260708-l9w5jhsw	265	25	85	85	CD
cord-260708-l9w5jhsw	265	26	]	]	-RRB-
cord-260708-l9w5jhsw	265	27	similar	similar	JJ
cord-260708-l9w5jhsw	265	28	to	to	IN
cord-260708-l9w5jhsw	265	29	that	that	DT
cord-260708-l9w5jhsw	265	30	often	often	RB
cord-260708-l9w5jhsw	265	31	found	find	VBN
cord-260708-l9w5jhsw	265	32	in	in	IN
cord-260708-l9w5jhsw	265	33	mammalian	mammalian	JJ
cord-260708-l9w5jhsw	265	34	DUBs	dub	NNS
cord-260708-l9w5jhsw	265	35	,	,	,
cord-260708-l9w5jhsw	265	36	and	and	CC
cord-260708-l9w5jhsw	265	37	experimental	experimental	JJ
cord-260708-l9w5jhsw	265	38	evidence	evidence	NN
cord-260708-l9w5jhsw	265	39	showed	show	VBD
cord-260708-l9w5jhsw	265	40	that	that	IN
cord-260708-l9w5jhsw	265	41	this	this	DT
cord-260708-l9w5jhsw	265	42	protease	protease	NN
cord-260708-l9w5jhsw	265	43	domain	domain	NN
cord-260708-l9w5jhsw	265	44	in	in	IN
cord-260708-l9w5jhsw	265	45	the	the	DT
cord-260708-l9w5jhsw	265	46	viral	viral	JJ
cord-260708-l9w5jhsw	265	47	protein	protein	NN
cord-260708-l9w5jhsw	265	48	indeed	indeed	RB
cord-260708-l9w5jhsw	265	49	deconjugated	deconjugate	VBD
cord-260708-l9w5jhsw	265	50	Ub	Ub	NNP
cord-260708-l9w5jhsw	265	51	and	and	CC
cord-260708-l9w5jhsw	265	52	ISG15	isg15	NN
cord-260708-l9w5jhsw	265	53	.	.	.
cord-260708-l9w5jhsw	266	1	Global	global	JJ
cord-260708-l9w5jhsw	266	2	ubiquitination	ubiquitination	NN
cord-260708-l9w5jhsw	266	3	and	and	CC
cord-260708-l9w5jhsw	266	4	ISGylation	isgylation	NN
cord-260708-l9w5jhsw	266	5	levels	level	NNS
cord-260708-l9w5jhsw	266	6	were	be	VBD
cord-260708-l9w5jhsw	266	7	greatly	greatly	RB
cord-260708-l9w5jhsw	266	8	reduced	reduce	VBN
cord-260708-l9w5jhsw	266	9	in	in	IN
cord-260708-l9w5jhsw	266	10	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	266	11	/	/	SYM
cord-260708-l9w5jhsw	266	12	GV	GV	NNP
cord-260708-l9w5jhsw	266	13	-	-	HYPH
cord-260708-l9w5jhsw	266	14	infected	infect	VBN
cord-260708-l9w5jhsw	266	15	cells	cell	NNS
cord-260708-l9w5jhsw	266	16	[	[	-LRB-
cord-260708-l9w5jhsw	266	17	84	84	CD
cord-260708-l9w5jhsw	266	18	]	]	-RRB-
cord-260708-l9w5jhsw	266	19	,	,	,
cord-260708-l9w5jhsw	266	20	and	and	CC
cord-260708-l9w5jhsw	266	21	overexpression	overexpression	NN
cord-260708-l9w5jhsw	266	22	of	of	IN
cord-260708-l9w5jhsw	266	23	the	the	DT
cord-260708-l9w5jhsw	266	24	amino	amino	NN
cord-260708-l9w5jhsw	266	25	-	-	HYPH
cord-260708-l9w5jhsw	266	26	terminal	terminal	NN
cord-260708-l9w5jhsw	266	27	end	end	NN
cord-260708-l9w5jhsw	266	28	of	of	IN
cord-260708-l9w5jhsw	266	29	the	the	DT
cord-260708-l9w5jhsw	266	30	L	l	NN
cord-260708-l9w5jhsw	266	31	proteins	protein	NNS
cord-260708-l9w5jhsw	266	32	of	of	IN
cord-260708-l9w5jhsw	266	33	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	266	34	,	,	,
cord-260708-l9w5jhsw	266	35	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	266	36	or	or	CC
cord-260708-l9w5jhsw	266	37	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	266	38	in	in	IN
cord-260708-l9w5jhsw	266	39	cell	cell	NN
cord-260708-l9w5jhsw	266	40	culture	culture	NN
cord-260708-l9w5jhsw	266	41	resulted	result	VBD
cord-260708-l9w5jhsw	266	42	in	in	IN
cord-260708-l9w5jhsw	266	43	a	a	DT
cord-260708-l9w5jhsw	266	44	similar	similar	JJ
cord-260708-l9w5jhsw	266	45	reduction	reduction	NN
cord-260708-l9w5jhsw	266	46	in	in	IN
cord-260708-l9w5jhsw	266	47	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	266	48	-	-	:
cord-260708-l9w5jhsw	266	49	and	and	CC
cord-260708-l9w5jhsw	266	50	ISG15-conjugated	isg15-conjugate	VBN
cord-260708-l9w5jhsw	266	51	proteins	protein	NNS
cord-260708-l9w5jhsw	266	52	[	[	-LRB-
cord-260708-l9w5jhsw	266	53	10	10	CD
cord-260708-l9w5jhsw	266	54	,	,	,
cord-260708-l9w5jhsw	266	55	30	30	CD
cord-260708-l9w5jhsw	266	56	,	,	,
cord-260708-l9w5jhsw	266	57	69	69	CD
cord-260708-l9w5jhsw	266	58	,	,	,
cord-260708-l9w5jhsw	266	59	84	84	CD
cord-260708-l9w5jhsw	266	60	]	]	-RRB-
cord-260708-l9w5jhsw	266	61	.	.	.
cord-260708-l9w5jhsw	267	1	The	the	DT
cord-260708-l9w5jhsw	267	2	L	L	NNP
cord-260708-l9w5jhsw	267	3	protein	protein	NN
cord-260708-l9w5jhsw	267	4	OTU	otu	NN
cord-260708-l9w5jhsw	267	5	domains	domain	NNS
cord-260708-l9w5jhsw	267	6	of	of	IN
cord-260708-l9w5jhsw	267	7	several	several	JJ
cord-260708-l9w5jhsw	267	8	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	267	9	have	have	VBP
cord-260708-l9w5jhsw	267	10	been	be	VBN
cord-260708-l9w5jhsw	267	11	shown	show	VBN
cord-260708-l9w5jhsw	267	12	to	to	TO
cord-260708-l9w5jhsw	267	13	block	block	VB
cord-260708-l9w5jhsw	267	14	IFNb	IFNb	NNS
cord-260708-l9w5jhsw	267	15	induction	induction	NN
cord-260708-l9w5jhsw	267	16	and	and	CC
cord-260708-l9w5jhsw	267	17	the	the	DT
cord-260708-l9w5jhsw	267	18	actions	action	NNS
cord-260708-l9w5jhsw	267	19	of	of	IN
cord-260708-l9w5jhsw	267	20	type	type	NN
cord-260708-l9w5jhsw	267	21	I	-PRON-	PRP
cord-260708-l9w5jhsw	267	22	and	and	CC
cord-260708-l9w5jhsw	267	23	type	type	NN
cord-260708-l9w5jhsw	267	24	II	ii	CD
cord-260708-l9w5jhsw	267	25	IFNs	IFNs	NNP
cord-260708-l9w5jhsw	267	26	[	[	-LRB-
cord-260708-l9w5jhsw	267	27	10	10	CD
cord-260708-l9w5jhsw	267	28	,	,	,
cord-260708-l9w5jhsw	267	29	69	69	CD
cord-260708-l9w5jhsw	267	30	,	,	,
cord-260708-l9w5jhsw	267	31	84	84	CD
cord-260708-l9w5jhsw	267	32	]	]	-RRB-
cord-260708-l9w5jhsw	267	33	.	.	.
cord-260708-l9w5jhsw	268	1	Interestingly	interestingly	RB
cord-260708-l9w5jhsw	268	2	,	,	,
cord-260708-l9w5jhsw	268	3	at	at	IN
cord-260708-l9w5jhsw	268	4	high	high	JJ
cord-260708-l9w5jhsw	268	5	enough	enough	JJ
cord-260708-l9w5jhsw	268	6	concentrations	concentration	NNS
cord-260708-l9w5jhsw	268	7	,	,	,
cord-260708-l9w5jhsw	268	8	even	even	RB
cord-260708-l9w5jhsw	268	9	catalytically	catalytically	RB
cord-260708-l9w5jhsw	268	10	inactive	inactive	JJ
cord-260708-l9w5jhsw	268	11	OTUs	otu	NNS
cord-260708-l9w5jhsw	268	12	are	be	VBP
cord-260708-l9w5jhsw	268	13	capable	capable	JJ
cord-260708-l9w5jhsw	268	14	of	of	IN
cord-260708-l9w5jhsw	268	15	blocking	block	VBG
cord-260708-l9w5jhsw	268	16	IFNainduced	ifnainduced	JJ
cord-260708-l9w5jhsw	268	17	transcription	transcription	NN
cord-260708-l9w5jhsw	268	18	[	[	-LRB-
cord-260708-l9w5jhsw	268	19	10	10	CD
cord-260708-l9w5jhsw	268	20	,	,	,
cord-260708-l9w5jhsw	268	21	69	69	CD
cord-260708-l9w5jhsw	268	22	]	]	-RRB-
cord-260708-l9w5jhsw	268	23	.	.	.
cord-260708-l9w5jhsw	269	1	This	this	DT
cord-260708-l9w5jhsw	269	2	suggests	suggest	VBZ
cord-260708-l9w5jhsw	269	3	that	that	IN
cord-260708-l9w5jhsw	269	4	catalytically	catalytically	RB
cord-260708-l9w5jhsw	269	5	inactive	inactive	JJ
cord-260708-l9w5jhsw	269	6	OTU	otu	NN
cord-260708-l9w5jhsw	269	7	domain	domain	NN
cord-260708-l9w5jhsw	269	8	proteins	protein	NNS
cord-260708-l9w5jhsw	269	9	are	be	VBP
cord-260708-l9w5jhsw	269	10	still	still	RB
cord-260708-l9w5jhsw	269	11	capable	capable	JJ
cord-260708-l9w5jhsw	269	12	of	of	IN
cord-260708-l9w5jhsw	269	13	sequestering	sequester	VBG
cord-260708-l9w5jhsw	269	14	specific	specific	JJ
cord-260708-l9w5jhsw	269	15	ubiquitinated	ubiquitinated	JJ
cord-260708-l9w5jhsw	269	16	or	or	CC
cord-260708-l9w5jhsw	269	17	ISG15ylated	isg15ylated	JJ
cord-260708-l9w5jhsw	269	18	targets	target	NNS
cord-260708-l9w5jhsw	269	19	by	by	IN
cord-260708-l9w5jhsw	269	20	binding	bind	VBG
cord-260708-l9w5jhsw	269	21	to	to	IN
cord-260708-l9w5jhsw	269	22	them	-PRON-	PRP
cord-260708-l9w5jhsw	269	23	.	.	.
cord-260708-l9w5jhsw	270	1	The	the	DT
cord-260708-l9w5jhsw	270	2	nsp2	nsp2	NNP
cord-260708-l9w5jhsw	270	3	protein	protein	NN
cord-260708-l9w5jhsw	270	4	of	of	IN
cord-260708-l9w5jhsw	270	5	EAV	EAV	NNP
cord-260708-l9w5jhsw	270	6	and	and	CC
cord-260708-l9w5jhsw	270	7	PRRSV	PRRSV	NNP
cord-260708-l9w5jhsw	270	8	also	also	RB
cord-260708-l9w5jhsw	270	9	contain	contain	VBP
cord-260708-l9w5jhsw	270	10	OTUlike	otulike	JJ
cord-260708-l9w5jhsw	270	11	domains	domain	NNS
cord-260708-l9w5jhsw	270	12	[	[	-LRB-
cord-260708-l9w5jhsw	270	13	69	69	CD
cord-260708-l9w5jhsw	270	14	]	]	-RRB-
cord-260708-l9w5jhsw	270	15	.	.	.
cord-260708-l9w5jhsw	271	1	Recently	recently	RB
cord-260708-l9w5jhsw	271	2	,	,	,
cord-260708-l9w5jhsw	271	3	it	-PRON-	PRP
cord-260708-l9w5jhsw	271	4	was	be	VBD
cord-260708-l9w5jhsw	271	5	shown	show	VBN
cord-260708-l9w5jhsw	271	6	that	that	IN
cord-260708-l9w5jhsw	271	7	both	both	CC
cord-260708-l9w5jhsw	271	8	the	the	DT
cord-260708-l9w5jhsw	271	9	nsp2	nsp2	NNP
cord-260708-l9w5jhsw	271	10	of	of	IN
cord-260708-l9w5jhsw	271	11	EAV	EAV	NNP
cord-260708-l9w5jhsw	271	12	and	and	CC
cord-260708-l9w5jhsw	271	13	the	the	DT
cord-260708-l9w5jhsw	271	14	OTU	OTU	NNP
cord-260708-l9w5jhsw	271	15	domain	domain	NN
cord-260708-l9w5jhsw	271	16	of	of	IN
cord-260708-l9w5jhsw	271	17	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	271	18	L	L	NNP
cord-260708-l9w5jhsw	271	19	protein	protein	NN
cord-260708-l9w5jhsw	271	20	are	be	VBP
cord-260708-l9w5jhsw	271	21	able	able	JJ
cord-260708-l9w5jhsw	271	22	to	to	TO
cord-260708-l9w5jhsw	271	23	deubiquitinate	deubiquitinate	VB
cord-260708-l9w5jhsw	271	24	RIG	RIG	NNP
cord-260708-l9w5jhsw	271	25	-	-	:
cord-260708-l9w5jhsw	271	26	I	I	NNP
cord-260708-l9w5jhsw	271	27	and	and	CC
cord-260708-l9w5jhsw	271	28	hence	hence	RB
cord-260708-l9w5jhsw	271	29	block	block	VB
cord-260708-l9w5jhsw	271	30	RIG	rig	NN
cord-260708-l9w5jhsw	271	31	-	-	HYPH
cord-260708-l9w5jhsw	271	32	I	i	NN
cord-260708-l9w5jhsw	271	33	-	-	HYPH
cord-260708-l9w5jhsw	271	34	mediated	mediate	VBN
cord-260708-l9w5jhsw	271	35	activation	activation	NN
cord-260708-l9w5jhsw	271	36	of	of	IN
cord-260708-l9w5jhsw	271	37	IFNb	IFNb	NNPS
cord-260708-l9w5jhsw	271	38	[	[	-LRB-
cord-260708-l9w5jhsw	271	39	168	168	CD
cord-260708-l9w5jhsw	271	40	]	]	-RRB-
cord-260708-l9w5jhsw	271	41	.	.	.
cord-260708-l9w5jhsw	272	1	Interestingly	interestingly	RB
cord-260708-l9w5jhsw	272	2	,	,	,
cord-260708-l9w5jhsw	272	3	the	the	DT
cord-260708-l9w5jhsw	272	4	RNA	RNA	NNP
cord-260708-l9w5jhsw	272	5	of	of	IN
cord-260708-l9w5jhsw	272	6	neither	neither	CC
cord-260708-l9w5jhsw	272	7	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	272	8	nor	nor	CC
cord-260708-l9w5jhsw	272	9	EAV	EAV	NNP
cord-260708-l9w5jhsw	272	10	appears	appear	VBZ
cord-260708-l9w5jhsw	272	11	to	to	TO
cord-260708-l9w5jhsw	272	12	activate	activate	VB
cord-260708-l9w5jhsw	272	13	RIG	rig	NN
cord-260708-l9w5jhsw	272	14	-	-	:
cord-260708-l9w5jhsw	272	15	I	i	NN
cord-260708-l9w5jhsw	272	16	[	[	-LRB-
cord-260708-l9w5jhsw	272	17	78	78	CD
cord-260708-l9w5jhsw	272	18	,	,	,
cord-260708-l9w5jhsw	272	19	168	168	CD
cord-260708-l9w5jhsw	272	20	]	]	-RRB-
cord-260708-l9w5jhsw	272	21	,	,	,
cord-260708-l9w5jhsw	272	22	so	so	RB
cord-260708-l9w5jhsw	273	1	the	the	DT
cord-260708-l9w5jhsw	273	2	fact	fact	NN
cord-260708-l9w5jhsw	273	3	that	that	IN
cord-260708-l9w5jhsw	273	4	these	these	DT
cord-260708-l9w5jhsw	273	5	viruses	virus	NNS
cord-260708-l9w5jhsw	273	6	have	have	VBP
cord-260708-l9w5jhsw	273	7	evolved	evolve	VBN
cord-260708-l9w5jhsw	273	8	specific	specific	JJ
cord-260708-l9w5jhsw	273	9	mechanisms	mechanism	NNS
cord-260708-l9w5jhsw	273	10	to	to	TO
cord-260708-l9w5jhsw	273	11	inhibit	inhibit	VB
cord-260708-l9w5jhsw	273	12	the	the	DT
cord-260708-l9w5jhsw	273	13	RIG	rig	NN
cord-260708-l9w5jhsw	273	14	-	-	HYPH
cord-260708-l9w5jhsw	273	15	I	i	NN
cord-260708-l9w5jhsw	273	16	-	-	HYPH
cord-260708-l9w5jhsw	273	17	mediated	mediate	VBN
cord-260708-l9w5jhsw	273	18	induction	induction	NN
cord-260708-l9w5jhsw	273	19	of	of	IN
cord-260708-l9w5jhsw	273	20	IFNb	IFNb	NNS
cord-260708-l9w5jhsw	273	21	suggests	suggest	VBZ
cord-260708-l9w5jhsw	273	22	that	that	IN
cord-260708-l9w5jhsw	273	23	RIG	rig	NN
cord-260708-l9w5jhsw	273	24	-	-	:
cord-260708-l9w5jhsw	273	25	I	-PRON-	PRP
cord-260708-l9w5jhsw	273	26	still	still	RB
cord-260708-l9w5jhsw	273	27	has	have	VBZ
cord-260708-l9w5jhsw	273	28	a	a	DT
cord-260708-l9w5jhsw	273	29	function	function	NN
cord-260708-l9w5jhsw	273	30	in	in	IN
cord-260708-l9w5jhsw	273	31	the	the	DT
cord-260708-l9w5jhsw	273	32	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	273	33	response	response	NN
cord-260708-l9w5jhsw	273	34	to	to	IN
cord-260708-l9w5jhsw	273	35	these	these	DT
cord-260708-l9w5jhsw	273	36	viruses	virus	NNS
cord-260708-l9w5jhsw	273	37	.	.	.
cord-260708-l9w5jhsw	274	1	However	however	RB
cord-260708-l9w5jhsw	274	2	,	,	,
cord-260708-l9w5jhsw	274	3	unlike	unlike	IN
cord-260708-l9w5jhsw	274	4	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	274	5	,	,	,
cord-260708-l9w5jhsw	274	6	the	the	DT
cord-260708-l9w5jhsw	274	7	vRNA	vrna	JJ
cord-260708-l9w5jhsw	274	8	of	of	IN
cord-260708-l9w5jhsw	274	9	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	274	10	/	/	SYM
cord-260708-l9w5jhsw	274	11	GV	GV	NNP
cord-260708-l9w5jhsw	274	12	does	do	VBZ
cord-260708-l9w5jhsw	274	13	activate	activate	VB
cord-260708-l9w5jhsw	274	14	transcription	transcription	NN
cord-260708-l9w5jhsw	274	15	from	from	IN
cord-260708-l9w5jhsw	274	16	the	the	DT
cord-260708-l9w5jhsw	274	17	IFNb	ifnb	JJ
cord-260708-l9w5jhsw	274	18	promoter	promoter	NN
cord-260708-l9w5jhsw	274	19	(	(	-LRB-
cord-260708-l9w5jhsw	274	20	Lasecka	Lasecka	NNPS
cord-260708-l9w5jhsw	274	21	and	and	CC
cord-260708-l9w5jhsw	274	22	Baron	Baron	NNP
cord-260708-l9w5jhsw	274	23	,	,	,
cord-260708-l9w5jhsw	274	24	unpublished	unpublished	JJ
cord-260708-l9w5jhsw	274	25	observations	observation	NNS
cord-260708-l9w5jhsw	274	26	)	)	-RRB-
cord-260708-l9w5jhsw	274	27	.	.	.
cord-260708-l9w5jhsw	275	1	The	the	DT
cord-260708-l9w5jhsw	275	2	ability	ability	NN
cord-260708-l9w5jhsw	275	3	to	to	TO
cord-260708-l9w5jhsw	275	4	directly	directly	RB
cord-260708-l9w5jhsw	275	5	block	block	VB
cord-260708-l9w5jhsw	275	6	the	the	DT
cord-260708-l9w5jhsw	275	7	RIG	rig	NN
cord-260708-l9w5jhsw	275	8	-	-	:
cord-260708-l9w5jhsw	275	9	I	-PRON-	PRP
cord-260708-l9w5jhsw	275	10	pathway	pathway	NN
cord-260708-l9w5jhsw	275	11	would	would	MD
cord-260708-l9w5jhsw	275	12	therefore	therefore	RB
cord-260708-l9w5jhsw	275	13	be	be	VB
cord-260708-l9w5jhsw	275	14	particularly	particularly	RB
cord-260708-l9w5jhsw	275	15	important	important	JJ
cord-260708-l9w5jhsw	275	16	for	for	IN
cord-260708-l9w5jhsw	275	17	this	this	DT
cord-260708-l9w5jhsw	275	18	virus	virus	NN
cord-260708-l9w5jhsw	275	19	.	.	.
cord-260708-l9w5jhsw	276	1	Comparison	comparison	NN
cord-260708-l9w5jhsw	276	2	of	of	IN
cord-260708-l9w5jhsw	276	3	the	the	DT
cord-260708-l9w5jhsw	276	4	OTU	OTU	NNP
cord-260708-l9w5jhsw	276	5	domains	domain	NNS
cord-260708-l9w5jhsw	276	6	of	of	IN
cord-260708-l9w5jhsw	276	7	different	different	JJ
cord-260708-l9w5jhsw	276	8	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	276	9	revealed	reveal	VBD
cord-260708-l9w5jhsw	276	10	some	some	DT
cord-260708-l9w5jhsw	276	11	differences	difference	NNS
cord-260708-l9w5jhsw	276	12	between	between	IN
cord-260708-l9w5jhsw	276	13	their	-PRON-	PRP$
cord-260708-l9w5jhsw	276	14	affinity	affinity	NN
cord-260708-l9w5jhsw	276	15	for	for	IN
cord-260708-l9w5jhsw	276	16	different	different	JJ
cord-260708-l9w5jhsw	276	17	types	type	NNS
cord-260708-l9w5jhsw	276	18	of	of	IN
cord-260708-l9w5jhsw	276	19	poly	poly	JJ
cord-260708-l9w5jhsw	276	20	-	-	HYPH
cord-260708-l9w5jhsw	276	21	Ub	ub	JJ
cord-260708-l9w5jhsw	276	22	and	and	CC
cord-260708-l9w5jhsw	276	23	ISG15	isg15	NN
cord-260708-l9w5jhsw	276	24	[	[	-LRB-
cord-260708-l9w5jhsw	276	25	30	30	CD
cord-260708-l9w5jhsw	276	26	]	]	-RRB-
cord-260708-l9w5jhsw	276	27	.	.	.
cord-260708-l9w5jhsw	277	1	For	for	IN
cord-260708-l9w5jhsw	277	2	instance	instance	NN
cord-260708-l9w5jhsw	277	3	,	,	,
cord-260708-l9w5jhsw	277	4	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	277	5	shows	show	VBZ
cord-260708-l9w5jhsw	277	6	a	a	DT
cord-260708-l9w5jhsw	277	7	higher	high	JJR
cord-260708-l9w5jhsw	277	8	affinity	affinity	NN
cord-260708-l9w5jhsw	277	9	for	for	IN
cord-260708-l9w5jhsw	277	10	K63-poly	K63-poly	NNP
cord-260708-l9w5jhsw	277	11	-	-	HYPH
cord-260708-l9w5jhsw	277	12	Ub	Ub	NNP
cord-260708-l9w5jhsw	277	13	than	than	IN
cord-260708-l9w5jhsw	277	14	K48-poly	K48-poly	NNP
cord-260708-l9w5jhsw	277	15	-	-	HYPH
cord-260708-l9w5jhsw	277	16	Ub	Ub	NNP
cord-260708-l9w5jhsw	277	17	,	,	,
cord-260708-l9w5jhsw	277	18	and	and	CC
cord-260708-l9w5jhsw	277	19	the	the	DT
cord-260708-l9w5jhsw	277	20	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	277	21	OTU	OTU	NNP
cord-260708-l9w5jhsw	277	22	was	be	VBD
cord-260708-l9w5jhsw	277	23	more	more	RBR
cord-260708-l9w5jhsw	277	24	active	active	JJ
cord-260708-l9w5jhsw	277	25	in	in	IN
cord-260708-l9w5jhsw	277	26	the	the	DT
cord-260708-l9w5jhsw	277	27	deubiquitination	deubiquitination	NN
cord-260708-l9w5jhsw	277	28	of	of	IN
cord-260708-l9w5jhsw	277	29	host	host	NN
cord-260708-l9w5jhsw	277	30	proteins	protein	NNS
cord-260708-l9w5jhsw	277	31	than	than	IN
cord-260708-l9w5jhsw	277	32	the	the	DT
cord-260708-l9w5jhsw	277	33	OTUs	otu	NNS
cord-260708-l9w5jhsw	277	34	of	of	IN
cord-260708-l9w5jhsw	277	35	either	either	CC
cord-260708-l9w5jhsw	277	36	NSDV	NSDV	NNP
cord-260708-l9w5jhsw	277	37	or	or	CC
cord-260708-l9w5jhsw	277	38	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	277	39	[	[	-LRB-
cord-260708-l9w5jhsw	277	40	10	10	CD
cord-260708-l9w5jhsw	277	41	,	,	,
cord-260708-l9w5jhsw	277	42	30	30	CD
cord-260708-l9w5jhsw	277	43	,	,	,
cord-260708-l9w5jhsw	277	44	84	84	CD
cord-260708-l9w5jhsw	277	45	]	]	-RRB-
cord-260708-l9w5jhsw	277	46	.	.	.
cord-260708-l9w5jhsw	278	1	On	on	IN
cord-260708-l9w5jhsw	278	2	the	the	DT
cord-260708-l9w5jhsw	278	3	other	other	JJ
cord-260708-l9w5jhsw	278	4	hand	hand	NN
cord-260708-l9w5jhsw	278	5	,	,	,
cord-260708-l9w5jhsw	278	6	while	while	IN
cord-260708-l9w5jhsw	278	7	the	the	DT
cord-260708-l9w5jhsw	278	8	ERVEV	ERVEV	NNP
cord-260708-l9w5jhsw	278	9	OTU	OTU	NNP
cord-260708-l9w5jhsw	278	10	appears	appear	VBZ
cord-260708-l9w5jhsw	278	11	to	to	TO
cord-260708-l9w5jhsw	278	12	bind	bind	VB
cord-260708-l9w5jhsw	278	13	any	any	DT
cord-260708-l9w5jhsw	278	14	poly	poly	JJ
cord-260708-l9w5jhsw	278	15	-	-	HYPH
cord-260708-l9w5jhsw	278	16	Ub	Ub	NNP
cord-260708-l9w5jhsw	278	17	weakly	weakly	RB
cord-260708-l9w5jhsw	278	18	(	(	-LRB-
cord-260708-l9w5jhsw	278	19	when	when	WRB
cord-260708-l9w5jhsw	278	20	compared	compare	VBN
cord-260708-l9w5jhsw	278	21	to	to	IN
cord-260708-l9w5jhsw	278	22	those	those	DT
cord-260708-l9w5jhsw	278	23	of	of	IN
cord-260708-l9w5jhsw	278	24	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	278	25	and	and	CC
cord-260708-l9w5jhsw	278	26	DUGV	DUGV	NNP
cord-260708-l9w5jhsw	278	27	)	)	-RRB-
cord-260708-l9w5jhsw	278	28	,	,	,
cord-260708-l9w5jhsw	278	29	it	-PRON-	PRP
cord-260708-l9w5jhsw	278	30	had	have	VBD
cord-260708-l9w5jhsw	278	31	higher	high	JJR
cord-260708-l9w5jhsw	278	32	affinity	affinity	NN
cord-260708-l9w5jhsw	278	33	for	for	IN
cord-260708-l9w5jhsw	278	34	ISG15	isg15	NN
cord-260708-l9w5jhsw	278	35	[	[	-LRB-
cord-260708-l9w5jhsw	278	36	30	30	CD
cord-260708-l9w5jhsw	278	37	]	]	-RRB-
cord-260708-l9w5jhsw	278	38	.	.	.
cord-260708-l9w5jhsw	279	1	This	this	DT
cord-260708-l9w5jhsw	279	2	may	may	MD
cord-260708-l9w5jhsw	279	3	indicate	indicate	VB
cord-260708-l9w5jhsw	279	4	that	that	IN
cord-260708-l9w5jhsw	279	5	different	different	JJ
cord-260708-l9w5jhsw	279	6	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	279	7	have	have	VBP
cord-260708-l9w5jhsw	279	8	adopted	adopt	VBN
cord-260708-l9w5jhsw	279	9	slightly	slightly	RB
cord-260708-l9w5jhsw	279	10	different	different	JJ
cord-260708-l9w5jhsw	279	11	ways	way	NNS
cord-260708-l9w5jhsw	279	12	of	of	IN
cord-260708-l9w5jhsw	279	13	utilising	utilise	VBG
cord-260708-l9w5jhsw	279	14	their	-PRON-	PRP$
cord-260708-l9w5jhsw	279	15	core	core	NN
cord-260708-l9w5jhsw	279	16	deubiquitinating	deubiquitinating	NN
cord-260708-l9w5jhsw	279	17	and	and	CC
cord-260708-l9w5jhsw	279	18	deISGylating	deisgylate	VBG
cord-260708-l9w5jhsw	279	19	activities	activity	NNS
cord-260708-l9w5jhsw	279	20	,	,	,
cord-260708-l9w5jhsw	279	21	which	which	WDT
cord-260708-l9w5jhsw	279	22	might	may	MD
cord-260708-l9w5jhsw	279	23	reflect	reflect	VB
cord-260708-l9w5jhsw	279	24	the	the	DT
cord-260708-l9w5jhsw	279	25	wide	wide	JJ
cord-260708-l9w5jhsw	279	26	range	range	NN
cord-260708-l9w5jhsw	279	27	of	of	IN
cord-260708-l9w5jhsw	279	28	pathogenicity	pathogenicity	NN
cord-260708-l9w5jhsw	279	29	caused	cause	VBN
cord-260708-l9w5jhsw	279	30	by	by	IN
cord-260708-l9w5jhsw	279	31	these	these	DT
cord-260708-l9w5jhsw	279	32	viruses	virus	NNS
cord-260708-l9w5jhsw	279	33	,	,	,
cord-260708-l9w5jhsw	279	34	or	or	CC
cord-260708-l9w5jhsw	279	35	differences	difference	NNS
cord-260708-l9w5jhsw	279	36	in	in	IN
cord-260708-l9w5jhsw	279	37	the	the	DT
cord-260708-l9w5jhsw	279	38	requirements	requirement	NNS
cord-260708-l9w5jhsw	279	39	imposed	impose	VBN
cord-260708-l9w5jhsw	279	40	on	on	IN
cord-260708-l9w5jhsw	279	41	these	these	DT
cord-260708-l9w5jhsw	279	42	viruses	virus	NNS
cord-260708-l9w5jhsw	279	43	by	by	IN
cord-260708-l9w5jhsw	279	44	their	-PRON-	PRP$
cord-260708-l9w5jhsw	279	45	arthropod	arthropod	JJ
cord-260708-l9w5jhsw	279	46	hosts	host	NNS
cord-260708-l9w5jhsw	279	47	,	,	,
cord-260708-l9w5jhsw	279	48	about	about	IN
cord-260708-l9w5jhsw	279	49	which	which	WDT
cord-260708-l9w5jhsw	279	50	we	-PRON-	PRP
cord-260708-l9w5jhsw	279	51	know	know	VBP
cord-260708-l9w5jhsw	279	52	very	very	RB
cord-260708-l9w5jhsw	279	53	little	little	JJ
cord-260708-l9w5jhsw	279	54	.	.	.
cord-260708-l9w5jhsw	280	1	ISG15	ISG15	NNP
cord-260708-l9w5jhsw	280	2	is	be	VBZ
cord-260708-l9w5jhsw	280	3	not	not	RB
cord-260708-l9w5jhsw	280	4	as	as	RB
cord-260708-l9w5jhsw	280	5	strongly	strongly	RB
cord-260708-l9w5jhsw	280	6	conserved	conserve	VBN
cord-260708-l9w5jhsw	280	7	as	as	IN
cord-260708-l9w5jhsw	280	8	ubiquitin	ubiquitin	JJ
cord-260708-l9w5jhsw	280	9	among	among	IN
cord-260708-l9w5jhsw	280	10	different	different	JJ
cord-260708-l9w5jhsw	280	11	species	specie	NNS
cord-260708-l9w5jhsw	280	12	,	,	,
cord-260708-l9w5jhsw	280	13	even	even	RB
cord-260708-l9w5jhsw	280	14	mammals	mammal	NNS
cord-260708-l9w5jhsw	280	15	,	,	,
cord-260708-l9w5jhsw	280	16	so	so	CC
cord-260708-l9w5jhsw	280	17	there	there	EX
cord-260708-l9w5jhsw	280	18	can	can	MD
cord-260708-l9w5jhsw	280	19	be	be	VB
cord-260708-l9w5jhsw	280	20	real	real	JJ
cord-260708-l9w5jhsw	280	21	effects	effect	NNS
cord-260708-l9w5jhsw	280	22	of	of	IN
cord-260708-l9w5jhsw	280	23	species	species	NN
cord-260708-l9w5jhsw	280	24	preference	preference	NN
cord-260708-l9w5jhsw	280	25	in	in	IN
cord-260708-l9w5jhsw	280	26	ISG15	isg15	NN
cord-260708-l9w5jhsw	280	27	binding	binding	NN
cord-260708-l9w5jhsw	280	28	/	/	SYM
cord-260708-l9w5jhsw	280	29	cleavage	cleavage	NN
cord-260708-l9w5jhsw	280	30	,	,	,
cord-260708-l9w5jhsw	280	31	e.g.	e.g.	RB
cord-260708-l9w5jhsw	280	32	,	,	,
cord-260708-l9w5jhsw	280	33	the	the	DT
cord-260708-l9w5jhsw	280	34	CCHFV	CCHFV	NNP
cord-260708-l9w5jhsw	280	35	OTU	OTU	NNP
cord-260708-l9w5jhsw	280	36	appears	appear	VBZ
cord-260708-l9w5jhsw	280	37	to	to	TO
cord-260708-l9w5jhsw	280	38	show	show	VB
cord-260708-l9w5jhsw	280	39	a	a	DT
cord-260708-l9w5jhsw	280	40	preference	preference	NN
cord-260708-l9w5jhsw	280	41	for	for	IN
cord-260708-l9w5jhsw	280	42	ISG15	isg15	NN
cord-260708-l9w5jhsw	280	43	of	of	IN
cord-260708-l9w5jhsw	280	44	human	human	JJ
cord-260708-l9w5jhsw	280	45	origin	origin	NN
cord-260708-l9w5jhsw	280	46	over	over	IN
cord-260708-l9w5jhsw	280	47	that	that	DT
cord-260708-l9w5jhsw	280	48	of	of	IN
cord-260708-l9w5jhsw	280	49	mouse	mouse	NN
cord-260708-l9w5jhsw	280	50	origin	origin	NN
cord-260708-l9w5jhsw	280	51	,	,	,
cord-260708-l9w5jhsw	280	52	while	while	IN
cord-260708-l9w5jhsw	280	53	ERVEV	ERVEV	NNP
cord-260708-l9w5jhsw	280	54	appears	appear	VBZ
cord-260708-l9w5jhsw	280	55	to	to	TO
cord-260708-l9w5jhsw	280	56	recognise	recognise	VB
cord-260708-l9w5jhsw	280	57	both	both	DT
cord-260708-l9w5jhsw	280	58	human	human	JJ
cord-260708-l9w5jhsw	280	59	and	and	CC
cord-260708-l9w5jhsw	280	60	mouse	mouse	NN
cord-260708-l9w5jhsw	280	61	ISG15s	isg15s	NN
cord-260708-l9w5jhsw	280	62	equally	equally	RB
cord-260708-l9w5jhsw	280	63	[	[	-LRB-
cord-260708-l9w5jhsw	280	64	30	30	CD
cord-260708-l9w5jhsw	280	65	]	]	-RRB-
cord-260708-l9w5jhsw	280	66	.	.	.
cord-260708-l9w5jhsw	281	1	The	the	DT
cord-260708-l9w5jhsw	281	2	better	well	RBR
cord-260708-l9w5jhsw	281	3	binding	binding	NN
cord-260708-l9w5jhsw	281	4	of	of	IN
cord-260708-l9w5jhsw	281	5	the	the	DT
cord-260708-l9w5jhsw	281	6	murine	murine	NN
cord-260708-l9w5jhsw	281	7	ISG15	isg15	NN
cord-260708-l9w5jhsw	281	8	by	by	IN
cord-260708-l9w5jhsw	281	9	the	the	DT
cord-260708-l9w5jhsw	281	10	ERVEV	ERVEV	NNP
cord-260708-l9w5jhsw	281	11	OTU	OTU	NNP
cord-260708-l9w5jhsw	281	12	may	may	MD
cord-260708-l9w5jhsw	281	13	be	be	VB
cord-260708-l9w5jhsw	281	14	associated	associate	VBN
cord-260708-l9w5jhsw	281	15	with	with	IN
cord-260708-l9w5jhsw	281	16	the	the	DT
cord-260708-l9w5jhsw	281	17	homology	homology	NN
cord-260708-l9w5jhsw	281	18	between	between	IN
cord-260708-l9w5jhsw	281	19	the	the	DT
cord-260708-l9w5jhsw	281	20	ISG15	isg15	NN
cord-260708-l9w5jhsw	281	21	of	of	IN
cord-260708-l9w5jhsw	281	22	mouse	mouse	NN
cord-260708-l9w5jhsw	281	23	and	and	CC
cord-260708-l9w5jhsw	281	24	the	the	DT
cord-260708-l9w5jhsw	281	25	white	white	JJ
cord-260708-l9w5jhsw	281	26	-	-	HYPH
cord-260708-l9w5jhsw	281	27	toothed	toothed	JJ
cord-260708-l9w5jhsw	281	28	shrew	shrew	NN
cord-260708-l9w5jhsw	281	29	from	from	IN
cord-260708-l9w5jhsw	281	30	which	which	WDT
cord-260708-l9w5jhsw	281	31	ERVEV	ERVEV	NNP
cord-260708-l9w5jhsw	281	32	is	be	VBZ
cord-260708-l9w5jhsw	281	33	commonly	commonly	RB
cord-260708-l9w5jhsw	281	34	isolated	isolate	VBN
cord-260708-l9w5jhsw	281	35	[	[	-LRB-
cord-260708-l9w5jhsw	281	36	34	34	CD
cord-260708-l9w5jhsw	281	37	,	,	,
cord-260708-l9w5jhsw	281	38	184	184	CD
cord-260708-l9w5jhsw	281	39	]	]	-RRB-
cord-260708-l9w5jhsw	281	40	.	.	.
cord-260708-l9w5jhsw	282	1	Nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	282	2	share	share	VBP
cord-260708-l9w5jhsw	282	3	many	many	JJ
cord-260708-l9w5jhsw	282	4	of	of	IN
cord-260708-l9w5jhsw	282	5	their	-PRON-	PRP$
cord-260708-l9w5jhsw	282	6	features	feature	NNS
cord-260708-l9w5jhsw	282	7	with	with	IN
cord-260708-l9w5jhsw	282	8	other	other	JJ
cord-260708-l9w5jhsw	282	9	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	282	10	,	,	,
cord-260708-l9w5jhsw	283	1	e.g.	e.g.	RB
cord-260708-l9w5jhsw	283	2	,	,	,
cord-260708-l9w5jhsw	283	3	replication	replication	NN
cord-260708-l9w5jhsw	283	4	in	in	IN
cord-260708-l9w5jhsw	283	5	the	the	DT
cord-260708-l9w5jhsw	283	6	cytoplasm	cytoplasm	NN
cord-260708-l9w5jhsw	283	7	,	,	,
cord-260708-l9w5jhsw	283	8	budding	bud	VBG
cord-260708-l9w5jhsw	283	9	in	in	IN
cord-260708-l9w5jhsw	283	10	the	the	DT
cord-260708-l9w5jhsw	283	11	Golgi	Golgi	NNP
cord-260708-l9w5jhsw	283	12	,	,	,
cord-260708-l9w5jhsw	283	13	and	and	CC
cord-260708-l9w5jhsw	283	14	their	-PRON-	PRP$
cord-260708-l9w5jhsw	283	15	coding	coding	NN
cord-260708-l9w5jhsw	283	16	and	and	CC
cord-260708-l9w5jhsw	283	17	RNA	RNA	NNP
cord-260708-l9w5jhsw	283	18	replication	replication	NN
cord-260708-l9w5jhsw	283	19	strategy	strategy	NN
cord-260708-l9w5jhsw	283	20	.	.	.
cord-260708-l9w5jhsw	284	1	From	from	IN
cord-260708-l9w5jhsw	284	2	phylogenetic	phylogenetic	JJ
cord-260708-l9w5jhsw	284	3	studies	study	NNS
cord-260708-l9w5jhsw	284	4	,	,	,
cord-260708-l9w5jhsw	284	5	the	the	DT
cord-260708-l9w5jhsw	284	6	members	member	NNS
cord-260708-l9w5jhsw	284	7	of	of	IN
cord-260708-l9w5jhsw	284	8	the	the	DT
cord-260708-l9w5jhsw	284	9	genus	genus	NN
cord-260708-l9w5jhsw	284	10	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	284	11	appear	appear	VBP
cord-260708-l9w5jhsw	284	12	to	to	TO
cord-260708-l9w5jhsw	284	13	be	be	VB
cord-260708-l9w5jhsw	284	14	most	most	RBS
cord-260708-l9w5jhsw	284	15	closely	closely	RB
cord-260708-l9w5jhsw	284	16	related	related	JJ
cord-260708-l9w5jhsw	284	17	to	to	IN
cord-260708-l9w5jhsw	284	18	those	those	DT
cord-260708-l9w5jhsw	284	19	of	of	IN
cord-260708-l9w5jhsw	284	20	the	the	DT
cord-260708-l9w5jhsw	284	21	genus	genus	NN
cord-260708-l9w5jhsw	284	22	Phlebovirus	Phlebovirus	NNP
cord-260708-l9w5jhsw	284	23	of	of	IN
cord-260708-l9w5jhsw	284	24	all	all	DT
cord-260708-l9w5jhsw	284	25	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	284	26	[	[	-LRB-
cord-260708-l9w5jhsw	284	27	108	108	CD
cord-260708-l9w5jhsw	284	28	,	,	,
cord-260708-l9w5jhsw	284	29	131	131	CD
cord-260708-l9w5jhsw	284	30	,	,	,
cord-260708-l9w5jhsw	284	31	139	139	CD
cord-260708-l9w5jhsw	284	32	,	,	,
cord-260708-l9w5jhsw	284	33	177	177	CD
cord-260708-l9w5jhsw	284	34	]	]	-RRB-
cord-260708-l9w5jhsw	284	35	.	.	.
cord-260708-l9w5jhsw	285	1	However	however	RB
cord-260708-l9w5jhsw	285	2	,	,	,
cord-260708-l9w5jhsw	285	3	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	285	4	possess	possess	VBP
cord-260708-l9w5jhsw	285	5	many	many	JJ
cord-260708-l9w5jhsw	285	6	features	feature	NNS
cord-260708-l9w5jhsw	285	7	not	not	RB
cord-260708-l9w5jhsw	285	8	found	find	VBN
cord-260708-l9w5jhsw	285	9	in	in	IN
cord-260708-l9w5jhsw	285	10	other	other	JJ
cord-260708-l9w5jhsw	285	11	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	285	12	.	.	.
cord-260708-l9w5jhsw	286	1	Nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	286	2	appear	appear	VBP
cord-260708-l9w5jhsw	286	3	to	to	TO
cord-260708-l9w5jhsw	286	4	have	have	VB
cord-260708-l9w5jhsw	286	5	complex	complex	JJ
cord-260708-l9w5jhsw	286	6	processing	processing	NN
cord-260708-l9w5jhsw	286	7	of	of	IN
cord-260708-l9w5jhsw	286	8	their	-PRON-	PRP$
cord-260708-l9w5jhsw	286	9	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	286	10	,	,	,
cord-260708-l9w5jhsw	286	11	which	which	WDT
cord-260708-l9w5jhsw	286	12	involves	involve	VBZ
cord-260708-l9w5jhsw	286	13	the	the	DT
cord-260708-l9w5jhsw	286	14	actions	action	NNS
cord-260708-l9w5jhsw	286	15	of	of	IN
cord-260708-l9w5jhsw	286	16	cellular	cellular	JJ
cord-260708-l9w5jhsw	286	17	proteases	protease	NNS
cord-260708-l9w5jhsw	286	18	such	such	JJ
cord-260708-l9w5jhsw	286	19	as	as	IN
cord-260708-l9w5jhsw	286	20	SKI-1	SKI-1	NNP
cord-260708-l9w5jhsw	286	21	/	/	SYM
cord-260708-l9w5jhsw	286	22	S1P	s1p	NN
cord-260708-l9w5jhsw	286	23	-	-	HYPH
cord-260708-l9w5jhsw	286	24	like	like	JJ
cord-260708-l9w5jhsw	286	25	proteases	protease	NNS
cord-260708-l9w5jhsw	286	26	and	and	CC
cord-260708-l9w5jhsw	286	27	furin	furin	NN
cord-260708-l9w5jhsw	286	28	.	.	.
cord-260708-l9w5jhsw	287	1	The	the	DT
cord-260708-l9w5jhsw	287	2	proteins	protein	NNS
cord-260708-l9w5jhsw	287	3	of	of	IN
cord-260708-l9w5jhsw	287	4	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	287	5	also	also	RB
cord-260708-l9w5jhsw	287	6	contain	contain	VBP
cord-260708-l9w5jhsw	287	7	domains	domain	NNS
cord-260708-l9w5jhsw	287	8	that	that	WDT
cord-260708-l9w5jhsw	287	9	have	have	VBP
cord-260708-l9w5jhsw	287	10	not	not	RB
cord-260708-l9w5jhsw	287	11	been	be	VBN
cord-260708-l9w5jhsw	287	12	observed	observe	VBN
cord-260708-l9w5jhsw	287	13	in	in	IN
cord-260708-l9w5jhsw	287	14	other	other	JJ
cord-260708-l9w5jhsw	287	15	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	287	16	,	,	,
cord-260708-l9w5jhsw	287	17	such	such	JJ
cord-260708-l9w5jhsw	287	18	as	as	IN
cord-260708-l9w5jhsw	287	19	the	the	DT
cord-260708-l9w5jhsw	287	20	L	L	NNP
cord-260708-l9w5jhsw	287	21	protein	protein	NN
cord-260708-l9w5jhsw	287	22	OTU	OTU	NNP
cord-260708-l9w5jhsw	287	23	domain	domain	NN
cord-260708-l9w5jhsw	287	24	.	.	.
cord-260708-l9w5jhsw	288	1	Nairoviruses	Nairoviruses	NNP
cord-260708-l9w5jhsw	288	2	express	express	VBP
cord-260708-l9w5jhsw	288	3	a	a	DT
cord-260708-l9w5jhsw	288	4	secreted	secrete	VBN
cord-260708-l9w5jhsw	288	5	mucin	mucin	NN
cord-260708-l9w5jhsw	288	6	-	-	HYPH
cord-260708-l9w5jhsw	288	7	like	like	JJ
cord-260708-l9w5jhsw	288	8	domain	domain	NN
cord-260708-l9w5jhsw	288	9	,	,	,
cord-260708-l9w5jhsw	288	10	which	which	WDT
cord-260708-l9w5jhsw	288	11	may	may	MD
cord-260708-l9w5jhsw	288	12	play	play	VB
cord-260708-l9w5jhsw	288	13	an	an	DT
cord-260708-l9w5jhsw	288	14	essential	essential	JJ
cord-260708-l9w5jhsw	288	15	role	role	NN
cord-260708-l9w5jhsw	288	16	in	in	IN
cord-260708-l9w5jhsw	288	17	the	the	DT
cord-260708-l9w5jhsw	288	18	pathogenicity	pathogenicity	NN
cord-260708-l9w5jhsw	288	19	of	of	IN
cord-260708-l9w5jhsw	288	20	the	the	DT
cord-260708-l9w5jhsw	288	21	virus	virus	NN
cord-260708-l9w5jhsw	288	22	[	[	-LRB-
cord-260708-l9w5jhsw	288	23	154	154	CD
cord-260708-l9w5jhsw	288	24	,	,	,
cord-260708-l9w5jhsw	288	25	188	188	CD
cord-260708-l9w5jhsw	288	26	]	]	-RRB-
cord-260708-l9w5jhsw	288	27	.	.	.
cord-260708-l9w5jhsw	289	1	Structural	structural	JJ
cord-260708-l9w5jhsw	289	2	similarity	similarity	NN
cord-260708-l9w5jhsw	289	3	between	between	IN
cord-260708-l9w5jhsw	289	4	the	the	DT
cord-260708-l9w5jhsw	289	5	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	289	6	N	N	NNP
cord-260708-l9w5jhsw	289	7	protein	protein	NN
cord-260708-l9w5jhsw	289	8	globular	globular	JJ
cord-260708-l9w5jhsw	289	9	domain	domain	NN
cord-260708-l9w5jhsw	289	10	or	or	CC
cord-260708-l9w5jhsw	289	11	the	the	DT
cord-260708-l9w5jhsw	289	12	RdRp	RdRp	NNP
cord-260708-l9w5jhsw	289	13	region	region	NN
cord-260708-l9w5jhsw	289	14	of	of	IN
cord-260708-l9w5jhsw	289	15	its	-PRON-	PRP$
cord-260708-l9w5jhsw	289	16	L	L	NNP
cord-260708-l9w5jhsw	289	17	protein	protein	NN
cord-260708-l9w5jhsw	289	18	and	and	CC
cord-260708-l9w5jhsw	289	19	equivalent	equivalent	JJ
cord-260708-l9w5jhsw	289	20	proteins	protein	NNS
cord-260708-l9w5jhsw	289	21	of	of	IN
cord-260708-l9w5jhsw	289	22	arenaviruses	arenavirus	NNS
cord-260708-l9w5jhsw	289	23	has	have	VBZ
cord-260708-l9w5jhsw	289	24	been	be	VBN
cord-260708-l9w5jhsw	289	25	taken	take	VBN
cord-260708-l9w5jhsw	289	26	to	to	TO
cord-260708-l9w5jhsw	289	27	suggest	suggest	VB
cord-260708-l9w5jhsw	289	28	that	that	IN
cord-260708-l9w5jhsw	289	29	the	the	DT
cord-260708-l9w5jhsw	289	30	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	289	31	are	be	VBP
cord-260708-l9w5jhsw	289	32	more	more	RBR
cord-260708-l9w5jhsw	289	33	closely	closely	RB
cord-260708-l9w5jhsw	289	34	related	relate	VBN
cord-260708-l9w5jhsw	289	35	to	to	IN
cord-260708-l9w5jhsw	289	36	arenaviruses	arenavirus	NNS
cord-260708-l9w5jhsw	289	37	than	than	IN
cord-260708-l9w5jhsw	289	38	to	to	IN
cord-260708-l9w5jhsw	289	39	members	member	NNS
cord-260708-l9w5jhsw	289	40	other	other	JJ
cord-260708-l9w5jhsw	289	41	genera	genus	NNS
cord-260708-l9w5jhsw	289	42	of	of	IN
cord-260708-l9w5jhsw	289	43	the	the	DT
cord-260708-l9w5jhsw	289	44	family	family	NN
cord-260708-l9w5jhsw	289	45	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	289	46	[	[	-LRB-
cord-260708-l9w5jhsw	289	47	31	31	CD
cord-260708-l9w5jhsw	289	48	,	,	,
cord-260708-l9w5jhsw	289	49	170	170	CD
cord-260708-l9w5jhsw	289	50	]	]	-RRB-
cord-260708-l9w5jhsw	289	51	,	,	,
cord-260708-l9w5jhsw	289	52	with	with	IN
cord-260708-l9w5jhsw	289	53	some	some	DT
cord-260708-l9w5jhsw	289	54	authors	author	NNS
cord-260708-l9w5jhsw	289	55	even	even	RB
cord-260708-l9w5jhsw	289	56	suggesting	suggest	VBG
cord-260708-l9w5jhsw	289	57	that	that	IN
cord-260708-l9w5jhsw	289	58	the	the	DT
cord-260708-l9w5jhsw	289	59	current	current	JJ
cord-260708-l9w5jhsw	289	60	classification	classification	NN
cord-260708-l9w5jhsw	289	61	of	of	IN
cord-260708-l9w5jhsw	289	62	the	the	DT
cord-260708-l9w5jhsw	289	63	Nairoviridae	Nairoviridae	NNP
cord-260708-l9w5jhsw	289	64	might	may	MD
cord-260708-l9w5jhsw	289	65	need	need	VB
cord-260708-l9w5jhsw	289	66	re	re	NN
cord-260708-l9w5jhsw	289	67	-	-	NN
cord-260708-l9w5jhsw	289	68	evaluation	evaluation	NN
cord-260708-l9w5jhsw	289	69	in	in	IN
cord-260708-l9w5jhsw	289	70	the	the	DT
cord-260708-l9w5jhsw	289	71	future	future	NN
cord-260708-l9w5jhsw	289	72	[	[	-LRB-
cord-260708-l9w5jhsw	289	73	31	31	CD
cord-260708-l9w5jhsw	289	74	]	]	-RRB-
cord-260708-l9w5jhsw	289	75	.	.	.
cord-260708-l9w5jhsw	290	1	Several	several	JJ
cord-260708-l9w5jhsw	290	2	areas	area	NNS
cord-260708-l9w5jhsw	290	3	for	for	IN
cord-260708-l9w5jhsw	290	4	future	future	JJ
cord-260708-l9w5jhsw	290	5	study	study	NN
cord-260708-l9w5jhsw	290	6	stand	stand	VB
cord-260708-l9w5jhsw	290	7	out	out	RP
cord-260708-l9w5jhsw	290	8	.	.	.
cord-260708-l9w5jhsw	291	1	Given	give	VBN
cord-260708-l9w5jhsw	291	2	that	that	IN
cord-260708-l9w5jhsw	291	3	the	the	DT
cord-260708-l9w5jhsw	291	4	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	291	5	are	be	VBP
cord-260708-l9w5jhsw	291	6	,	,	,
cord-260708-l9w5jhsw	291	7	in	in	IN
cord-260708-l9w5jhsw	291	8	general	general	JJ
cord-260708-l9w5jhsw	291	9	,	,	,
cord-260708-l9w5jhsw	291	10	tick	tick	NN
cord-260708-l9w5jhsw	291	11	-	-	HYPH
cord-260708-l9w5jhsw	291	12	borne	bear	VBN
cord-260708-l9w5jhsw	291	13	,	,	,
cord-260708-l9w5jhsw	291	14	while	while	IN
cord-260708-l9w5jhsw	291	15	most	most	JJS
cord-260708-l9w5jhsw	291	16	other	other	JJ
cord-260708-l9w5jhsw	291	17	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	291	18	are	be	VBP
cord-260708-l9w5jhsw	291	19	insect	insect	NN
cord-260708-l9w5jhsw	291	20	-	-	HYPH
cord-260708-l9w5jhsw	291	21	borne	bear	VBN
cord-260708-l9w5jhsw	291	22	,	,	,
cord-260708-l9w5jhsw	291	23	it	-PRON-	PRP
cord-260708-l9w5jhsw	291	24	is	be	VBZ
cord-260708-l9w5jhsw	291	25	to	to	TO
cord-260708-l9w5jhsw	291	26	be	be	VB
cord-260708-l9w5jhsw	291	27	expected	expect	VBN
cord-260708-l9w5jhsw	291	28	that	that	IN
cord-260708-l9w5jhsw	291	29	the	the	DT
cord-260708-l9w5jhsw	291	30	interaction	interaction	NN
cord-260708-l9w5jhsw	291	31	of	of	IN
cord-260708-l9w5jhsw	291	32	these	these	DT
cord-260708-l9w5jhsw	291	33	viruses	virus	NNS
cord-260708-l9w5jhsw	291	34	with	with	IN
cord-260708-l9w5jhsw	291	35	their	-PRON-	PRP$
cord-260708-l9w5jhsw	291	36	arthropod	arthropod	JJ
cord-260708-l9w5jhsw	291	37	hosts	host	NNS
cord-260708-l9w5jhsw	291	38	will	will	MD
cord-260708-l9w5jhsw	291	39	be	be	VB
cord-260708-l9w5jhsw	291	40	specific	specific	JJ
cord-260708-l9w5jhsw	291	41	to	to	IN
cord-260708-l9w5jhsw	291	42	the	the	DT
cord-260708-l9w5jhsw	291	43	virus	virus	NN
cord-260708-l9w5jhsw	291	44	genus	genus	NN
cord-260708-l9w5jhsw	291	45	and	and	CC
cord-260708-l9w5jhsw	291	46	need	need	VB
cord-260708-l9w5jhsw	291	47	specific	specific	JJ
cord-260708-l9w5jhsw	291	48	study	study	NN
cord-260708-l9w5jhsw	291	49	.	.	.
cord-260708-l9w5jhsw	292	1	Fortunately	fortunately	RB
cord-260708-l9w5jhsw	292	2	,	,	,
cord-260708-l9w5jhsw	292	3	expertise	expertise	NN
cord-260708-l9w5jhsw	292	4	with	with	IN
cord-260708-l9w5jhsw	292	5	handling	handle	VBG
cord-260708-l9w5jhsw	292	6	ixodid	ixodid	NN
cord-260708-l9w5jhsw	292	7	ticks	tick	NNS
cord-260708-l9w5jhsw	292	8	and	and	CC
cord-260708-l9w5jhsw	292	9	tick	tick	VB
cord-260708-l9w5jhsw	292	10	cell	cell	NN
cord-260708-l9w5jhsw	292	11	lines	line	NNS
cord-260708-l9w5jhsw	292	12	is	be	VBZ
cord-260708-l9w5jhsw	292	13	rapidly	rapidly	RB
cord-260708-l9w5jhsw	292	14	increasing	increase	VBG
cord-260708-l9w5jhsw	292	15	,	,	,
cord-260708-l9w5jhsw	292	16	and	and	CC
cord-260708-l9w5jhsw	292	17	it	-PRON-	PRP
cord-260708-l9w5jhsw	292	18	is	be	VBZ
cord-260708-l9w5jhsw	292	19	to	to	TO
cord-260708-l9w5jhsw	292	20	be	be	VB
cord-260708-l9w5jhsw	292	21	hoped	hope	VBN
cord-260708-l9w5jhsw	292	22	that	that	IN
cord-260708-l9w5jhsw	292	23	our	-PRON-	PRP$
cord-260708-l9w5jhsw	292	24	understanding	understanding	NN
cord-260708-l9w5jhsw	292	25	of	of	IN
cord-260708-l9w5jhsw	292	26	the	the	DT
cord-260708-l9w5jhsw	292	27	replication	replication	NN
cord-260708-l9w5jhsw	292	28	of	of	IN
cord-260708-l9w5jhsw	292	29	these	these	DT
cord-260708-l9w5jhsw	292	30	viruses	virus	NNS
cord-260708-l9w5jhsw	292	31	in	in	IN
cord-260708-l9w5jhsw	292	32	their	-PRON-	PRP$
cord-260708-l9w5jhsw	292	33	tick	tick	NN
cord-260708-l9w5jhsw	292	34	hosts	host	NNS
cord-260708-l9w5jhsw	292	35	will	will	MD
cord-260708-l9w5jhsw	292	36	catch	catch	VB
cord-260708-l9w5jhsw	292	37	up	up	RP
cord-260708-l9w5jhsw	292	38	with	with	IN
cord-260708-l9w5jhsw	292	39	our	-PRON-	PRP$
cord-260708-l9w5jhsw	292	40	knowledge	knowledge	NN
cord-260708-l9w5jhsw	292	41	of	of	IN
cord-260708-l9w5jhsw	292	42	what	what	WP
cord-260708-l9w5jhsw	292	43	is	be	VBZ
cord-260708-l9w5jhsw	292	44	happening	happen	VBG
cord-260708-l9w5jhsw	292	45	in	in	IN
cord-260708-l9w5jhsw	292	46	mammals	mammal	NNS
cord-260708-l9w5jhsw	292	47	.	.	.
cord-260708-l9w5jhsw	293	1	The	the	DT
cord-260708-l9w5jhsw	293	2	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	293	3	have	have	VBP
cord-260708-l9w5jhsw	293	4	been	be	VBN
cord-260708-l9w5jhsw	293	5	more	more	RBR
cord-260708-l9w5jhsw	293	6	resistant	resistant	JJ
cord-260708-l9w5jhsw	293	7	to	to	IN
cord-260708-l9w5jhsw	293	8	the	the	DT
cord-260708-l9w5jhsw	293	9	development	development	NN
cord-260708-l9w5jhsw	293	10	of	of	IN
cord-260708-l9w5jhsw	293	11	successful	successful	JJ
cord-260708-l9w5jhsw	293	12	reverse	reverse	NN
cord-260708-l9w5jhsw	293	13	genetics	genetic	NNS
cord-260708-l9w5jhsw	293	14	than	than	IN
cord-260708-l9w5jhsw	293	15	e.g.	e.g.	RB
cord-260708-l9w5jhsw	293	16	the	the	DT
cord-260708-l9w5jhsw	293	17	orthobunyaviruses	orthobunyaviruse	NNS
cord-260708-l9w5jhsw	293	18	or	or	CC
cord-260708-l9w5jhsw	293	19	the	the	DT
cord-260708-l9w5jhsw	293	20	phleboviruses	phleboviruse	NNS
cord-260708-l9w5jhsw	293	21	,	,	,
cord-260708-l9w5jhsw	293	22	and	and	CC
cord-260708-l9w5jhsw	293	23	development	development	NN
cord-260708-l9w5jhsw	293	24	of	of	IN
cord-260708-l9w5jhsw	293	25	such	such	PDT
cord-260708-l9w5jhsw	293	26	a	a	DT
cord-260708-l9w5jhsw	293	27	system	system	NN
cord-260708-l9w5jhsw	293	28	for	for	IN
cord-260708-l9w5jhsw	293	29	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	293	30	will	will	MD
cord-260708-l9w5jhsw	293	31	be	be	VB
cord-260708-l9w5jhsw	293	32	invaluable	invaluable	JJ
cord-260708-l9w5jhsw	293	33	in	in	IN
cord-260708-l9w5jhsw	293	34	helping	help	VBG
cord-260708-l9w5jhsw	293	35	us	-PRON-	PRP
cord-260708-l9w5jhsw	293	36	understand	understand	VB
cord-260708-l9w5jhsw	293	37	the	the	DT
cord-260708-l9w5jhsw	293	38	roles	role	NNS
cord-260708-l9w5jhsw	293	39	of	of	IN
cord-260708-l9w5jhsw	293	40	various	various	JJ
cord-260708-l9w5jhsw	293	41	nairovirus	nairovirus	JJ
cord-260708-l9w5jhsw	293	42	-	-	HYPH
cord-260708-l9w5jhsw	293	43	specific	specific	JJ
cord-260708-l9w5jhsw	293	44	domains	domain	NNS
cord-260708-l9w5jhsw	293	45	such	such	JJ
cord-260708-l9w5jhsw	293	46	as	as	IN
cord-260708-l9w5jhsw	293	47	the	the	DT
cord-260708-l9w5jhsw	293	48	topoisomerase	topoisomerase	NN
cord-260708-l9w5jhsw	293	49	-	-	HYPH
cord-260708-l9w5jhsw	293	50	like	like	JJ
cord-260708-l9w5jhsw	293	51	domain	domain	NN
cord-260708-l9w5jhsw	293	52	,	,	,
cord-260708-l9w5jhsw	293	53	C2H2-zinc	C2H2-zinc	NNP
cord-260708-l9w5jhsw	293	54	finger	finger	NN
cord-260708-l9w5jhsw	293	55	domain	domain	NN
cord-260708-l9w5jhsw	293	56	,	,	,
cord-260708-l9w5jhsw	293	57	leucine	leucine	NN
cord-260708-l9w5jhsw	293	58	zipper	zipper	NN
cord-260708-l9w5jhsw	293	59	motif	motif	NN
cord-260708-l9w5jhsw	293	60	,	,	,
cord-260708-l9w5jhsw	293	61	and	and	CC
cord-260708-l9w5jhsw	293	62	OTU	OTU	NNP
cord-260708-l9w5jhsw	293	63	domain	domain	NN
cord-260708-l9w5jhsw	293	64	of	of	IN
cord-260708-l9w5jhsw	293	65	the	the	DT
cord-260708-l9w5jhsw	293	66	L	L	NNP
cord-260708-l9w5jhsw	293	67	protein	protein	NN
cord-260708-l9w5jhsw	293	68	,	,	,
cord-260708-l9w5jhsw	293	69	or	or	CC
cord-260708-l9w5jhsw	293	70	the	the	DT
cord-260708-l9w5jhsw	293	71	NS	NS	NNP
cord-260708-l9w5jhsw	293	72	M	M	NNP
cord-260708-l9w5jhsw	293	73	and	and	CC
cord-260708-l9w5jhsw	293	74	mucinlike	mucinlike	JJ
cord-260708-l9w5jhsw	293	75	domain	domain	NN
cord-260708-l9w5jhsw	293	76	from	from	IN
cord-260708-l9w5jhsw	293	77	the	the	DT
cord-260708-l9w5jhsw	293	78	M	M	NNP
cord-260708-l9w5jhsw	293	79	segment	segment	NN
cord-260708-l9w5jhsw	293	80	,	,	,
cord-260708-l9w5jhsw	293	81	both	both	CC
cord-260708-l9w5jhsw	293	82	in	in	IN
cord-260708-l9w5jhsw	293	83	mammalian	mammalian	JJ
cord-260708-l9w5jhsw	293	84	and	and	CC
cord-260708-l9w5jhsw	293	85	arthropod	arthropod	JJ
cord-260708-l9w5jhsw	293	86	hosts	host	NNS
cord-260708-l9w5jhsw	293	87	.	.	.
cord-260708-l9w5jhsw	294	1	The	the	DT
cord-260708-l9w5jhsw	294	2	ability	ability	NN
cord-260708-l9w5jhsw	294	3	to	to	TO
cord-260708-l9w5jhsw	294	4	create	create	VB
cord-260708-l9w5jhsw	294	5	targeted	target	VBN
cord-260708-l9w5jhsw	294	6	mutations	mutation	NNS
cord-260708-l9w5jhsw	294	7	will	will	MD
cord-260708-l9w5jhsw	294	8	also	also	RB
cord-260708-l9w5jhsw	294	9	enable	enable	VB
cord-260708-l9w5jhsw	294	10	us	-PRON-	PRP
cord-260708-l9w5jhsw	294	11	to	to	TO
cord-260708-l9w5jhsw	294	12	more	more	RBR
cord-260708-l9w5jhsw	294	13	rapidly	rapidly	RB
cord-260708-l9w5jhsw	294	14	develop	develop	VB
cord-260708-l9w5jhsw	294	15	stably	stably	RB
cord-260708-l9w5jhsw	294	16	attenuated	attenuate	VBN
cord-260708-l9w5jhsw	294	17	viruses	virus	NNS
cord-260708-l9w5jhsw	294	18	that	that	WDT
cord-260708-l9w5jhsw	294	19	could	could	MD
cord-260708-l9w5jhsw	294	20	act	act	VB
cord-260708-l9w5jhsw	294	21	as	as	IN
cord-260708-l9w5jhsw	294	22	vaccines	vaccine	NNS
cord-260708-l9w5jhsw	294	23	.	.	.
cord-260708-l9w5jhsw	295	1	Presence	presence	NN
cord-260708-l9w5jhsw	295	2	of	of	IN
cord-260708-l9w5jhsw	295	3	broadly	broadly	RB
cord-260708-l9w5jhsw	295	4	reactive	reactive	JJ
cord-260708-l9w5jhsw	295	5	and	and	CC
cord-260708-l9w5jhsw	295	6	group	group	NN
cord-260708-l9w5jhsw	295	7	-	-	HYPH
cord-260708-l9w5jhsw	295	8	specific	specific	JJ
cord-260708-l9w5jhsw	295	9	neutralizing	neutralize	VBG
cord-260708-l9w5jhsw	295	10	epitopes	epitope	NNS
cord-260708-l9w5jhsw	295	11	on	on	IN
cord-260708-l9w5jhsw	295	12	newly	newly	RB
cord-260708-l9w5jhsw	295	13	described	describe	VBN
cord-260708-l9w5jhsw	295	14	isolates	isolate	NNS
cord-260708-l9w5jhsw	295	15	of	of	IN
cord-260708-l9w5jhsw	295	16	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	295	17	-	-	HYPH
cord-260708-l9w5jhsw	295	18	Congo	Congo	NNP
cord-260708-l9w5jhsw	295	19	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	295	20	fever	fever	NN
cord-260708-l9w5jhsw	295	21	virus	virus	NN
cord-260708-l9w5jhsw	295	22	Molecular	molecular	JJ
cord-260708-l9w5jhsw	295	23	basis	basis	NN
cord-260708-l9w5jhsw	295	24	for	for	IN
cord-260708-l9w5jhsw	295	25	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	295	26	and	and	CC
cord-260708-l9w5jhsw	295	27	ISG15	ISG15	NNP
cord-260708-l9w5jhsw	295	28	cross	cross	NN
cord-260708-l9w5jhsw	295	29	-	-	NN
cord-260708-l9w5jhsw	295	30	reactivity	reactivity	NN
cord-260708-l9w5jhsw	295	31	in	in	IN
cord-260708-l9w5jhsw	295	32	viral	viral	JJ
cord-260708-l9w5jhsw	295	33	ovarian	ovarian	JJ
cord-260708-l9w5jhsw	295	34	tumor	tumor	NN
cord-260708-l9w5jhsw	295	35	domains	domain	NNS
cord-260708-l9w5jhsw	295	36	Identification	identification	NN
cord-260708-l9w5jhsw	295	37	of	of	IN
cord-260708-l9w5jhsw	295	38	a	a	DT
cord-260708-l9w5jhsw	295	39	novel	novel	JJ
cord-260708-l9w5jhsw	295	40	C	c	NN
cord-260708-l9w5jhsw	295	41	-	-	HYPH
cord-260708-l9w5jhsw	295	42	terminal	terminal	NN
cord-260708-l9w5jhsw	295	43	cleavage	cleavage	NN
cord-260708-l9w5jhsw	295	44	of	of	IN
cord-260708-l9w5jhsw	295	45	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	295	46	-	-	HYPH
cord-260708-l9w5jhsw	295	47	Congo	Congo	NNP
cord-260708-l9w5jhsw	295	48	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	295	49	fever	fever	NN
cord-260708-l9w5jhsw	295	50	virus	virus	NN
cord-260708-l9w5jhsw	295	51	PreGN	pregn	NN
cord-260708-l9w5jhsw	295	52	that	that	WDT
cord-260708-l9w5jhsw	295	53	leads	lead	VBZ
cord-260708-l9w5jhsw	295	54	to	to	IN
cord-260708-l9w5jhsw	295	55	generation	generation	NN
cord-260708-l9w5jhsw	295	56	of	of	IN
cord-260708-l9w5jhsw	295	57	an	an	DT
cord-260708-l9w5jhsw	295	58	NSM	NSM	NNP
cord-260708-l9w5jhsw	295	59	protein	protein	NN
cord-260708-l9w5jhsw	295	60	Human	human	JJ
cord-260708-l9w5jhsw	295	61	MxA	mxa	NN
cord-260708-l9w5jhsw	295	62	protein	protein	NN
cord-260708-l9w5jhsw	295	63	inhibits	inhibit	VBZ
cord-260708-l9w5jhsw	295	64	the	the	DT
cord-260708-l9w5jhsw	295	65	replication	replication	NN
cord-260708-l9w5jhsw	295	66	of	of	IN
cord-260708-l9w5jhsw	295	67	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	295	68	-	-	HYPH
cord-260708-l9w5jhsw	295	69	Congo	Congo	NNP
cord-260708-l9w5jhsw	295	70	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	295	71	fever	fever	NN
cord-260708-l9w5jhsw	295	72	virus	virus	NN
cord-260708-l9w5jhsw	295	73	Role	role	NN
cord-260708-l9w5jhsw	295	74	of	of	IN
cord-260708-l9w5jhsw	295	75	actin	actin	NN
cord-260708-l9w5jhsw	295	76	filaments	filament	NNS
cord-260708-l9w5jhsw	295	77	in	in	IN
cord-260708-l9w5jhsw	295	78	targeting	target	VBG
cord-260708-l9w5jhsw	295	79	of	of	IN
cord-260708-l9w5jhsw	295	80	Crimean	crimean	JJ
cord-260708-l9w5jhsw	295	81	Congo	Congo	NNP
cord-260708-l9w5jhsw	295	82	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	295	83	fever	fever	NN
cord-260708-l9w5jhsw	295	84	virus	virus	NN
cord-260708-l9w5jhsw	295	85	nucleocapsid	nucleocapsid	NN
cord-260708-l9w5jhsw	295	86	protein	protein	NN
cord-260708-l9w5jhsw	295	87	to	to	IN
cord-260708-l9w5jhsw	295	88	perinuclear	perinuclear	NNP
cord-260708-l9w5jhsw	295	89	regions	region	NNS
cord-260708-l9w5jhsw	295	90	of	of	IN
cord-260708-l9w5jhsw	295	91	mammalian	mammalian	JJ
cord-260708-l9w5jhsw	295	92	cells	cell	NNS
cord-260708-l9w5jhsw	296	1	Type	type	NN
cord-260708-l9w5jhsw	297	1	I	-PRON-	PRP
cord-260708-l9w5jhsw	298	1	interferon	interferon	NN
cord-260708-l9w5jhsw	298	2	inhibits	inhibit	VBZ
cord-260708-l9w5jhsw	298	3	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	298	4	-	-	HYPH
cord-260708-l9w5jhsw	298	5	Congo	Congo	NNP
cord-260708-l9w5jhsw	298	6	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	298	7	fever	fever	NN
cord-260708-l9w5jhsw	298	8	virus	virus	NN
cord-260708-l9w5jhsw	298	9	in	in	IN
cord-260708-l9w5jhsw	298	10	human	human	JJ
cord-260708-l9w5jhsw	298	11	target	target	NN
cord-260708-l9w5jhsw	298	12	cells	cell	NNS
cord-260708-l9w5jhsw	299	1	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	299	2	-	-	HYPH
cord-260708-l9w5jhsw	299	3	Congo	Congo	NNP
cord-260708-l9w5jhsw	299	4	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	299	5	fever	fever	NN
cord-260708-l9w5jhsw	299	6	virus	virus	NN
cord-260708-l9w5jhsw	299	7	delays	delay	VBZ
cord-260708-l9w5jhsw	299	8	activation	activation	NN
cord-260708-l9w5jhsw	299	9	of	of	IN
cord-260708-l9w5jhsw	299	10	the	the	DT
cord-260708-l9w5jhsw	299	11	innate	innate	JJ
cord-260708-l9w5jhsw	299	12	immune	immune	JJ
cord-260708-l9w5jhsw	299	13	response	response	NN
cord-260708-l9w5jhsw	299	14	Analysis	Analysis	NNP
cord-260708-l9w5jhsw	299	15	of	of	IN
cord-260708-l9w5jhsw	299	16	oropouche	oropouche	NNP
cord-260708-l9w5jhsw	299	17	virus	virus	NN
cord-260708-l9w5jhsw	299	18	L	L	NNP
cord-260708-l9w5jhsw	299	19	protein	protein	NN
cord-260708-l9w5jhsw	299	20	amino	amino	NN
cord-260708-l9w5jhsw	299	21	acid	acid	NN
cord-260708-l9w5jhsw	299	22	sequence	sequence	NN
cord-260708-l9w5jhsw	299	23	showed	show	VBD
cord-260708-l9w5jhsw	299	24	the	the	DT
cord-260708-l9w5jhsw	299	25	presence	presence	NN
cord-260708-l9w5jhsw	299	26	of	of	IN
cord-260708-l9w5jhsw	299	27	an	an	DT
cord-260708-l9w5jhsw	299	28	additional	additional	JJ
cord-260708-l9w5jhsw	299	29	conserved	conserved	JJ
cord-260708-l9w5jhsw	299	30	region	region	NN
cord-260708-l9w5jhsw	299	31	that	that	WDT
cord-260708-l9w5jhsw	299	32	could	could	MD
cord-260708-l9w5jhsw	299	33	harbour	harbour	VB
cord-260708-l9w5jhsw	299	34	an	an	DT
cord-260708-l9w5jhsw	299	35	important	important	JJ
cord-260708-l9w5jhsw	299	36	role	role	NN
cord-260708-l9w5jhsw	299	37	for	for	IN
cord-260708-l9w5jhsw	299	38	the	the	DT
cord-260708-l9w5jhsw	299	39	polymerase	polymerase	NN
cord-260708-l9w5jhsw	299	40	activity	activity	NN
cord-260708-l9w5jhsw	299	41	Nucleocapsid	Nucleocapsid	NNP
cord-260708-l9w5jhsw	299	42	protein	protein	NN
cord-260708-l9w5jhsw	299	43	structures	structure	NNS
cord-260708-l9w5jhsw	299	44	from	from	IN
cord-260708-l9w5jhsw	299	45	orthobunyaviruses	orthobunyaviruse	NNS
cord-260708-l9w5jhsw	299	46	reveal	reveal	VBP
cord-260708-l9w5jhsw	299	47	insight	insight	NN
cord-260708-l9w5jhsw	299	48	into	into	IN
cord-260708-l9w5jhsw	299	49	ribonucleoprotein	ribonucleoprotein	NN
cord-260708-l9w5jhsw	299	50	architecture	architecture	NN
cord-260708-l9w5jhsw	299	51	and	and	CC
cord-260708-l9w5jhsw	299	52	RNA	RNA	NNP
cord-260708-l9w5jhsw	299	53	polymerization	polymerization	NN
cord-260708-l9w5jhsw	299	54	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	299	55	virus	virus	NN
cord-260708-l9w5jhsw	299	56	ovarian	ovarian	JJ
cord-260708-l9w5jhsw	299	57	tumour	tumour	NN
cord-260708-l9w5jhsw	299	58	domain	domain	NN
cord-260708-l9w5jhsw	299	59	interferes	interfere	VBZ
cord-260708-l9w5jhsw	299	60	with	with	IN
cord-260708-l9w5jhsw	299	61	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	299	62	/	/	SYM
cord-260708-l9w5jhsw	299	63	ISG15-regulated	isg15-regulate	VBN
cord-260708-l9w5jhsw	299	64	innate	innate	JJ
cord-260708-l9w5jhsw	299	65	immune	immune	JJ
cord-260708-l9w5jhsw	299	66	cell	cell	NN
cord-260708-l9w5jhsw	299	67	signalling	signal	VBG
cord-260708-l9w5jhsw	299	68	Otubains	Otubains	NNP
cord-260708-l9w5jhsw	299	69	:	:	:
cord-260708-l9w5jhsw	299	70	a	a	DT
cord-260708-l9w5jhsw	299	71	new	new	JJ
cord-260708-l9w5jhsw	299	72	family	family	NN
cord-260708-l9w5jhsw	299	73	of	of	IN
cord-260708-l9w5jhsw	299	74	cysteine	cysteine	NN
cord-260708-l9w5jhsw	299	75	proteases	protease	NNS
cord-260708-l9w5jhsw	299	76	in	in	IN
cord-260708-l9w5jhsw	299	77	the	the	DT
cord-260708-l9w5jhsw	299	78	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	299	79	pathway	pathway	NN
cord-260708-l9w5jhsw	299	80	5'-terminal	5'-terminal	CD
cord-260708-l9w5jhsw	299	81	cap	cap	NN
cord-260708-l9w5jhsw	299	82	structure	structure	NN
cord-260708-l9w5jhsw	299	83	in	in	IN
cord-260708-l9w5jhsw	299	84	eucaryotic	eucaryotic	JJ
cord-260708-l9w5jhsw	299	85	messenger	messenger	NN
cord-260708-l9w5jhsw	299	86	ribonucleic	ribonucleic	JJ
cord-260708-l9w5jhsw	299	87	acids	acid	NNS
cord-260708-l9w5jhsw	299	88	Viral	viral	JJ
cord-260708-l9w5jhsw	299	89	infections	infection	NNS
cord-260708-l9w5jhsw	299	90	in	in	IN
cord-260708-l9w5jhsw	299	91	laboratory	laboratory	NN
cord-260708-l9w5jhsw	299	92	personnel	personnel	NNS
cord-260708-l9w5jhsw	299	93	Role	role	NN
cord-260708-l9w5jhsw	299	94	of	of	IN
cord-260708-l9w5jhsw	299	95	the	the	DT
cord-260708-l9w5jhsw	299	96	conserved	conserve	VBN
cord-260708-l9w5jhsw	299	97	nucleotide	nucleotide	JJ
cord-260708-l9w5jhsw	299	98	mismatch	mismatch	NN
cord-260708-l9w5jhsw	299	99	within	within	IN
cord-260708-l9w5jhsw	299	100	3'-and	3'-and	CD
cord-260708-l9w5jhsw	299	101	5'-terminal	5'-terminal	CD
cord-260708-l9w5jhsw	299	102	regions	region	NNS
cord-260708-l9w5jhsw	299	103	of	of	IN
cord-260708-l9w5jhsw	299	104	Bunyamwera	Bunyamwera	NNP
cord-260708-l9w5jhsw	299	105	virus	virus	NN
cord-260708-l9w5jhsw	299	106	in	in	IN
cord-260708-l9w5jhsw	299	107	signaling	signal	VBG
cord-260708-l9w5jhsw	299	108	transcription	transcription	NN
cord-260708-l9w5jhsw	299	109	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	299	110	-	-	HYPH
cord-260708-l9w5jhsw	299	111	Congo	Congo	NNP
cord-260708-l9w5jhsw	299	112	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	299	113	fever	fever	NN
cord-260708-l9w5jhsw	299	114	virus	virus	NN
cord-260708-l9w5jhsw	299	115	glycoprotein	glycoprotein	NN
cord-260708-l9w5jhsw	299	116	processing	process	VBG
cord-260708-l9w5jhsw	299	117	by	by	IN
cord-260708-l9w5jhsw	299	118	the	the	DT
cord-260708-l9w5jhsw	299	119	endoprotease	endoprotease	NN
cord-260708-l9w5jhsw	300	1	SKI-1/	ski-1/	NN
cord-260708-l9w5jhsw	301	1	S1P	S1P	NNP
cord-260708-l9w5jhsw	301	2	is	be	VBZ
cord-260708-l9w5jhsw	301	3	critical	critical	JJ
cord-260708-l9w5jhsw	301	4	for	for	IN
cord-260708-l9w5jhsw	301	5	virus	virus	NN
cord-260708-l9w5jhsw	301	6	infectivity	infectivity	NN
cord-260708-l9w5jhsw	301	7	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	301	8	-	-	HYPH
cord-260708-l9w5jhsw	301	9	Congo	Congo	NNP
cord-260708-l9w5jhsw	301	10	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	301	11	fever	fever	NN
cord-260708-l9w5jhsw	301	12	virus	virus	NN
cord-260708-l9w5jhsw	301	13	-	-	HYPH
cord-260708-l9w5jhsw	301	14	encoded	encode	VBN
cord-260708-l9w5jhsw	301	15	ovarian	ovarian	JJ
cord-260708-l9w5jhsw	301	16	tumor	tumor	NN
cord-260708-l9w5jhsw	301	17	protease	protease	NN
cord-260708-l9w5jhsw	301	18	activity	activity	NN
cord-260708-l9w5jhsw	301	19	is	be	VBZ
cord-260708-l9w5jhsw	301	20	dispensable	dispensable	JJ
cord-260708-l9w5jhsw	301	21	for	for	IN
cord-260708-l9w5jhsw	301	22	virus	virus	NN
cord-260708-l9w5jhsw	301	23	RNA	rna	NN
cord-260708-l9w5jhsw	301	24	polymerase	polymerase	NN
cord-260708-l9w5jhsw	301	25	function	function	VBP
cord-260708-l9w5jhsw	301	26	Cellular	cellular	JJ
cord-260708-l9w5jhsw	301	27	localization	localization	NN
cord-260708-l9w5jhsw	301	28	and	and	CC
cord-260708-l9w5jhsw	301	29	antigenic	antigenic	JJ
cord-260708-l9w5jhsw	301	30	characterization	characterization	NN
cord-260708-l9w5jhsw	301	31	of	of	IN
cord-260708-l9w5jhsw	301	32	crimean	crimean	NNP
cord-260708-l9w5jhsw	301	33	-	-	HYPH
cord-260708-l9w5jhsw	301	34	congo	congo	NNP
cord-260708-l9w5jhsw	301	35	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	301	36	fever	fever	NN
cord-260708-l9w5jhsw	301	37	virus	virus	NN
cord-260708-l9w5jhsw	301	38	glycoproteins	glycoprotein	VBZ
cord-260708-l9w5jhsw	301	39	NSs	NSs	NNP
cord-260708-l9w5jhsw	301	40	protein	protein	NN
cord-260708-l9w5jhsw	301	41	of	of	IN
cord-260708-l9w5jhsw	301	42	Rift	Rift	NNP
cord-260708-l9w5jhsw	301	43	Valley	Valley	NNP
cord-260708-l9w5jhsw	301	44	fever	fever	NN
cord-260708-l9w5jhsw	301	45	virus	virus	NN
cord-260708-l9w5jhsw	302	1	blocks	block	NNS
cord-260708-l9w5jhsw	302	2	interferon	interferon	NN
cord-260708-l9w5jhsw	302	3	production	production	NN
cord-260708-l9w5jhsw	302	4	by	by	IN
cord-260708-l9w5jhsw	302	5	inhibiting	inhibit	VBG
cord-260708-l9w5jhsw	302	6	host	host	NN
cord-260708-l9w5jhsw	302	7	gene	gene	NN
cord-260708-l9w5jhsw	302	8	transcription	transcription	NN
cord-260708-l9w5jhsw	302	9	La	La	NNP
cord-260708-l9w5jhsw	302	10	Crosse	Crosse	NNP
cord-260708-l9w5jhsw	302	11	bunyavirus	bunyavirus	NN
cord-260708-l9w5jhsw	302	12	nonstructural	nonstructural	JJ
cord-260708-l9w5jhsw	302	13	protein	protein	NN
cord-260708-l9w5jhsw	302	14	NSs	NSs	NNP
cord-260708-l9w5jhsw	303	1	serves	serve	VBZ
cord-260708-l9w5jhsw	303	2	to	to	TO
cord-260708-l9w5jhsw	303	3	suppress	suppress	VB
cord-260708-l9w5jhsw	303	4	the	the	DT
cord-260708-l9w5jhsw	303	5	type	type	NN
cord-260708-l9w5jhsw	304	1	I	-PRON-	PRP
cord-260708-l9w5jhsw	304	2	interferon	interferon	VBD
cord-260708-l9w5jhsw	304	3	system	system	NN
cord-260708-l9w5jhsw	304	4	of	of	IN
cord-260708-l9w5jhsw	304	5	mammalian	mammalian	JJ
cord-260708-l9w5jhsw	304	6	hosts	host	NNS
cord-260708-l9w5jhsw	304	7	Molecular	molecular	JJ
cord-260708-l9w5jhsw	304	8	characterization	characterization	NN
cord-260708-l9w5jhsw	304	9	of	of	IN
cord-260708-l9w5jhsw	304	10	the	the	DT
cord-260708-l9w5jhsw	304	11	interferon	interferon	NN
cord-260708-l9w5jhsw	304	12	-	-	HYPH
cord-260708-l9w5jhsw	304	13	induced	induce	VBN
cord-260708-l9w5jhsw	304	14	15-kDa	15-kda	CD
cord-260708-l9w5jhsw	304	15	protein	protein	NN
cord-260708-l9w5jhsw	304	16	.	.	.
cord-260708-l9w5jhsw	305	1	Molecular	molecular	JJ
cord-260708-l9w5jhsw	305	2	cloning	cloning	NN
cord-260708-l9w5jhsw	305	3	and	and	CC
cord-260708-l9w5jhsw	305	4	nucleotide	nucleotide	JJ
cord-260708-l9w5jhsw	305	5	and	and	CC
cord-260708-l9w5jhsw	305	6	amino	amino	NN
cord-260708-l9w5jhsw	305	7	acid	acid	NN
cord-260708-l9w5jhsw	305	8	sequence	sequence	NN
cord-260708-l9w5jhsw	305	9	Structure	structure	NN
cord-260708-l9w5jhsw	305	10	and	and	CC
cord-260708-l9w5jhsw	305	11	morphogenesis	morphogenesis	NN
cord-260708-l9w5jhsw	305	12	of	of	IN
cord-260708-l9w5jhsw	305	13	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	305	14	virus	virus	NN
cord-260708-l9w5jhsw	305	15	(	(	-LRB-
cord-260708-l9w5jhsw	305	16	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	305	17	,	,	,
cord-260708-l9w5jhsw	305	18	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	305	19	)	)	-RRB-
cord-260708-l9w5jhsw	305	20	studied	study	VBN
cord-260708-l9w5jhsw	305	21	by	by	IN
cord-260708-l9w5jhsw	305	22	immunogold	immunogold	NNP
cord-260708-l9w5jhsw	305	23	electron	electron	NN
cord-260708-l9w5jhsw	305	24	microscopy	microscopy	NN
cord-260708-l9w5jhsw	305	25	of	of	IN
cord-260708-l9w5jhsw	305	26	ultrathin	ultrathin	JJ
cord-260708-l9w5jhsw	305	27	cryosections	cryosection	NNS
cord-260708-l9w5jhsw	305	28	Role	role	NN
cord-260708-l9w5jhsw	305	29	of	of	IN
cord-260708-l9w5jhsw	305	30	nucleolin	nucleolin	NNP
cord-260708-l9w5jhsw	305	31	in	in	IN
cord-260708-l9w5jhsw	305	32	human	human	JJ
cord-260708-l9w5jhsw	305	33	parainfluenza	parainfluenza	NNP
cord-260708-l9w5jhsw	305	34	virus	virus	NNP
cord-260708-l9w5jhsw	305	35	type	type	NN
cord-260708-l9w5jhsw	305	36	3	3	CD
cord-260708-l9w5jhsw	305	37	infection	infection	NN
cord-260708-l9w5jhsw	305	38	of	of	IN
cord-260708-l9w5jhsw	305	39	human	human	JJ
cord-260708-l9w5jhsw	305	40	lung	lung	NN
cord-260708-l9w5jhsw	305	41	epithelial	epithelial	NN
cord-260708-l9w5jhsw	305	42	cells	cell	NNS
cord-260708-l9w5jhsw	305	43	Genetic	genetic	JJ
cord-260708-l9w5jhsw	305	44	evidence	evidence	NN
cord-260708-l9w5jhsw	305	45	for	for	IN
cord-260708-l9w5jhsw	305	46	an	an	DT
cord-260708-l9w5jhsw	305	47	interferon	interferon	NN
cord-260708-l9w5jhsw	305	48	-	-	HYPH
cord-260708-l9w5jhsw	305	49	antagonistic	antagonistic	JJ
cord-260708-l9w5jhsw	305	50	function	function	NN
cord-260708-l9w5jhsw	305	51	of	of	IN
cord-260708-l9w5jhsw	305	52	rift	rift	NNP
cord-260708-l9w5jhsw	305	53	valley	valley	NNP
cord-260708-l9w5jhsw	305	54	fever	fever	NN
cord-260708-l9w5jhsw	305	55	virus	virus	NN
cord-260708-l9w5jhsw	305	56	nonstructural	nonstructural	JJ
cord-260708-l9w5jhsw	305	57	protein	protein	NN
cord-260708-l9w5jhsw	305	58	NSs	NSs	NNP
cord-260708-l9w5jhsw	305	59	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	305	60	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	305	61	S	S	NNP
cord-260708-l9w5jhsw	305	62	segment	segment	NN
cord-260708-l9w5jhsw	305	63	:	:	:
cord-260708-l9w5jhsw	305	64	correction	correction	NN
cord-260708-l9w5jhsw	305	65	of	of	IN
cord-260708-l9w5jhsw	305	66	published	publish	VBN
cord-260708-l9w5jhsw	305	67	sequence	sequence	NN
cord-260708-l9w5jhsw	305	68	and	and	CC
cord-260708-l9w5jhsw	305	69	comparison	comparison	NN
cord-260708-l9w5jhsw	305	70	of	of	IN
cord-260708-l9w5jhsw	305	71	five	five	CD
cord-260708-l9w5jhsw	305	72	isolates	isolate	NNS
cord-260708-l9w5jhsw	305	73	Inhibition	inhibition	NN
cord-260708-l9w5jhsw	305	74	of	of	IN
cord-260708-l9w5jhsw	305	75	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	305	76	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	305	77	replication	replication	NN
cord-260708-l9w5jhsw	305	78	by	by	IN
cord-260708-l9w5jhsw	305	79	human	human	JJ
cord-260708-l9w5jhsw	305	80	MxA	MxA	NNP
cord-260708-l9w5jhsw	305	81	protein	protein	NN
cord-260708-l9w5jhsw	306	1	Nosocomial	nosocomial	JJ
cord-260708-l9w5jhsw	306	2	outbreak	outbreak	NN
cord-260708-l9w5jhsw	306	3	of	of	IN
cord-260708-l9w5jhsw	306	4	viral	viral	JJ
cord-260708-l9w5jhsw	306	5	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	306	6	fever	fever	NN
cord-260708-l9w5jhsw	306	7	caused	cause	VBN
cord-260708-l9w5jhsw	306	8	by	by	IN
cord-260708-l9w5jhsw	306	9	Crimean	crimean	JJ
cord-260708-l9w5jhsw	306	10	Hemorrhagic	Hemorrhagic	NNP
cord-260708-l9w5jhsw	306	11	fever	fever	NN
cord-260708-l9w5jhsw	306	12	-	-	:
cord-260708-l9w5jhsw	306	13	Congo	Congo	NNP
cord-260708-l9w5jhsw	306	14	virus	virus	NN
cord-260708-l9w5jhsw	306	15	in	in	IN
cord-260708-l9w5jhsw	306	16	Pakistan	Pakistan	NNP
cord-260708-l9w5jhsw	306	17	Investigation	Investigation	NNP
cord-260708-l9w5jhsw	306	18	of	of	IN
cord-260708-l9w5jhsw	306	19	tick	tick	VB
cord-260708-l9w5jhsw	306	20	-	-	HYPH
cord-260708-l9w5jhsw	306	21	borne	bear	VBN
cord-260708-l9w5jhsw	306	22	viruses	virus	NNS
cord-260708-l9w5jhsw	306	23	as	as	IN
cord-260708-l9w5jhsw	306	24	pathogens	pathogen	NNS
cord-260708-l9w5jhsw	306	25	of	of	IN
cord-260708-l9w5jhsw	306	26	humans	human	NNS
cord-260708-l9w5jhsw	306	27	in	in	IN
cord-260708-l9w5jhsw	306	28	South	South	NNP
cord-260708-l9w5jhsw	306	29	Africa	Africa	NNP
cord-260708-l9w5jhsw	306	30	and	and	CC
cord-260708-l9w5jhsw	306	31	evidence	evidence	NN
cord-260708-l9w5jhsw	306	32	of	of	IN
cord-260708-l9w5jhsw	306	33	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	306	34	virus	virus	NN
cord-260708-l9w5jhsw	306	35	infection	infection	NN
cord-260708-l9w5jhsw	306	36	in	in	IN
cord-260708-l9w5jhsw	306	37	a	a	DT
cord-260708-l9w5jhsw	306	38	patient	patient	NN
cord-260708-l9w5jhsw	306	39	with	with	IN
cord-260708-l9w5jhsw	306	40	prolonged	prolonged	JJ
cord-260708-l9w5jhsw	306	41	thrombocytopenia	thrombocytopenia	NN
cord-260708-l9w5jhsw	306	42	Immunohistochemical	Immunohistochemical	NNP
cord-260708-l9w5jhsw	306	43	and	and	CC
cord-260708-l9w5jhsw	306	44	in	in	IN
cord-260708-l9w5jhsw	306	45	situ	situ	JJ
cord-260708-l9w5jhsw	306	46	localization	localization	NN
cord-260708-l9w5jhsw	306	47	of	of	IN
cord-260708-l9w5jhsw	306	48	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	306	49	-	-	HYPH
cord-260708-l9w5jhsw	306	50	Congo	Congo	NNP
cord-260708-l9w5jhsw	306	51	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	306	52	fever	fever	NN
cord-260708-l9w5jhsw	306	53	(	(	-LRB-
cord-260708-l9w5jhsw	306	54	CCHF	CCHF	NNP
cord-260708-l9w5jhsw	306	55	)	)	-RRB-
cord-260708-l9w5jhsw	306	56	virus	virus	NN
cord-260708-l9w5jhsw	306	57	in	in	IN
cord-260708-l9w5jhsw	306	58	human	human	JJ
cord-260708-l9w5jhsw	306	59	tissues	tissue	NNS
cord-260708-l9w5jhsw	306	60	and	and	CC
cord-260708-l9w5jhsw	306	61	implications	implication	NNS
cord-260708-l9w5jhsw	306	62	for	for	IN
cord-260708-l9w5jhsw	306	63	CCHF	CCHF	NNP
cord-260708-l9w5jhsw	306	64	pathogenesis	pathogenesis	NN
cord-260708-l9w5jhsw	307	1	Structural	structural	JJ
cord-260708-l9w5jhsw	307	2	analysis	analysis	NN
cord-260708-l9w5jhsw	307	3	of	of	IN
cord-260708-l9w5jhsw	307	4	a	a	DT
cord-260708-l9w5jhsw	307	5	viral	viral	JJ
cord-260708-l9w5jhsw	307	6	ovarian	ovarian	JJ
cord-260708-l9w5jhsw	307	7	tumor	tumor	NN
cord-260708-l9w5jhsw	307	8	domain	domain	NN
cord-260708-l9w5jhsw	307	9	protease	protease	NN
cord-260708-l9w5jhsw	307	10	from	from	IN
cord-260708-l9w5jhsw	307	11	the	the	DT
cord-260708-l9w5jhsw	307	12	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	307	13	-	-	HYPH
cord-260708-l9w5jhsw	307	14	Congo	Congo	NNP
cord-260708-l9w5jhsw	307	15	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	307	16	fever	fever	NN
cord-260708-l9w5jhsw	307	17	virus	virus	NN
cord-260708-l9w5jhsw	307	18	in	in	IN
cord-260708-l9w5jhsw	307	19	complex	complex	NN
cord-260708-l9w5jhsw	307	20	with	with	IN
cord-260708-l9w5jhsw	307	21	covalently	covalently	RB
cord-260708-l9w5jhsw	307	22	bonded	bond	VBN
cord-260708-l9w5jhsw	307	23	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	307	24	Diversity	diversity	NN
cord-260708-l9w5jhsw	307	25	of	of	IN
cord-260708-l9w5jhsw	307	26	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	307	27	and	and	CC
cord-260708-l9w5jhsw	307	28	ISG15	isg15	NN
cord-260708-l9w5jhsw	307	29	specificity	specificity	NN
cord-260708-l9w5jhsw	307	30	among	among	IN
cord-260708-l9w5jhsw	307	31	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	307	32	'	'	POS
cord-260708-l9w5jhsw	307	33	viral	viral	JJ
cord-260708-l9w5jhsw	307	34	ovarian	ovarian	JJ
cord-260708-l9w5jhsw	307	35	tumor	tumor	NN
cord-260708-l9w5jhsw	307	36	domain	domain	NN
cord-260708-l9w5jhsw	307	37	proteases	protease	NNS
cord-260708-l9w5jhsw	307	38	Structure	structure	NN
cord-260708-l9w5jhsw	307	39	,	,	,
cord-260708-l9w5jhsw	307	40	function	function	NN
cord-260708-l9w5jhsw	307	41	,	,	,
cord-260708-l9w5jhsw	307	42	and	and	CC
cord-260708-l9w5jhsw	307	43	evolution	evolution	NN
cord-260708-l9w5jhsw	307	44	of	of	IN
cord-260708-l9w5jhsw	307	45	the	the	DT
cord-260708-l9w5jhsw	307	46	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	307	47	-	-	HYPH
cord-260708-l9w5jhsw	307	48	Congo	Congo	NNP
cord-260708-l9w5jhsw	307	49	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	307	50	fever	fever	NN
cord-260708-l9w5jhsw	307	51	virus	virus	NN
cord-260708-l9w5jhsw	307	52	nucleocapsid	nucleocapsid	NN
cord-260708-l9w5jhsw	307	53	protein	protein	NN
cord-260708-l9w5jhsw	307	54	The	the	DT
cord-260708-l9w5jhsw	307	55	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	307	56	genus	genus	NN
cord-260708-l9w5jhsw	307	57	:	:	:
cord-260708-l9w5jhsw	307	58	serological	serological	JJ
cord-260708-l9w5jhsw	307	59	relationships	relationship	NNS
cord-260708-l9w5jhsw	308	1	Polypeptide	polypeptide	JJ
cord-260708-l9w5jhsw	308	2	synthesis	synthesis	NN
cord-260708-l9w5jhsw	308	3	of	of	IN
cord-260708-l9w5jhsw	308	4	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	308	5	virus	virus	NN
cord-260708-l9w5jhsw	308	6	,	,	,
cord-260708-l9w5jhsw	308	7	a	a	DT
cord-260708-l9w5jhsw	308	8	member	member	NN
cord-260708-l9w5jhsw	308	9	of	of	IN
cord-260708-l9w5jhsw	308	10	the	the	DT
cord-260708-l9w5jhsw	308	11	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	308	12	genus	genus	NN
cord-260708-l9w5jhsw	308	13	of	of	IN
cord-260708-l9w5jhsw	308	14	the	the	DT
cord-260708-l9w5jhsw	308	15	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	308	16	Erve	Erve	NNP
cord-260708-l9w5jhsw	308	17	virus	virus	NN
cord-260708-l9w5jhsw	308	18	,	,	,
cord-260708-l9w5jhsw	308	19	a	a	DT
cord-260708-l9w5jhsw	308	20	probable	probable	JJ
cord-260708-l9w5jhsw	308	21	member	member	NN
cord-260708-l9w5jhsw	308	22	of	of	IN
cord-260708-l9w5jhsw	308	23	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	308	24	family	family	NN
cord-260708-l9w5jhsw	308	25	isolated	isolate	VBN
cord-260708-l9w5jhsw	308	26	from	from	IN
cord-260708-l9w5jhsw	308	27	shrews	shrew	NNS
cord-260708-l9w5jhsw	308	28	(	(	-LRB-
cord-260708-l9w5jhsw	308	29	Crocidura	Crocidura	NNP
cord-260708-l9w5jhsw	308	30	russula	russula	NNP
cord-260708-l9w5jhsw	308	31	)	)	-RRB-
cord-260708-l9w5jhsw	308	32	in	in	IN
cord-260708-l9w5jhsw	308	33	France	France	NNP
cord-260708-l9w5jhsw	308	34	Conservation	Conservation	NNP
cord-260708-l9w5jhsw	308	35	of	of	IN
cord-260708-l9w5jhsw	308	36	structure	structure	NN
cord-260708-l9w5jhsw	308	37	and	and	CC
cord-260708-l9w5jhsw	308	38	mechanism	mechanism	NN
cord-260708-l9w5jhsw	308	39	between	between	IN
cord-260708-l9w5jhsw	308	40	eukaryotic	eukaryotic	JJ
cord-260708-l9w5jhsw	309	1	topoisomerase	topoisomerase	NN
cord-260708-l9w5jhsw	309	2	I	-PRON-	PRP
cord-260708-l9w5jhsw	309	3	and	and	CC
cord-260708-l9w5jhsw	309	4	site	site	NN
cord-260708-l9w5jhsw	309	5	-	-	HYPH
cord-260708-l9w5jhsw	309	6	specific	specific	JJ
cord-260708-l9w5jhsw	309	7	recombinases	recombinase	NNS
cord-260708-l9w5jhsw	310	1	Nucleolin	Nucleolin	NNP
cord-260708-l9w5jhsw	310	2	expressed	express	VBD
cord-260708-l9w5jhsw	310	3	at	at	IN
cord-260708-l9w5jhsw	310	4	the	the	DT
cord-260708-l9w5jhsw	310	5	cell	cell	NN
cord-260708-l9w5jhsw	310	6	surface	surface	NN
cord-260708-l9w5jhsw	310	7	is	be	VBZ
cord-260708-l9w5jhsw	310	8	a	a	DT
cord-260708-l9w5jhsw	310	9	marker	marker	NN
cord-260708-l9w5jhsw	310	10	of	of	IN
cord-260708-l9w5jhsw	310	11	endothelial	endothelial	JJ
cord-260708-l9w5jhsw	310	12	cells	cell	NNS
cord-260708-l9w5jhsw	310	13	in	in	IN
cord-260708-l9w5jhsw	310	14	angiogenic	angiogenic	JJ
cord-260708-l9w5jhsw	310	15	blood	blood	NN
cord-260708-l9w5jhsw	310	16	vessels	vessel	NNS
cord-260708-l9w5jhsw	311	1	The	the	DT
cord-260708-l9w5jhsw	311	2	3	3	CD
cord-260708-l9w5jhsw	311	3	'	'	POS
cord-260708-l9w5jhsw	311	4	terminal	terminal	NN
cord-260708-l9w5jhsw	311	5	RNA	RNA	NNP
cord-260708-l9w5jhsw	311	6	sequences	sequence	NNS
cord-260708-l9w5jhsw	311	7	of	of	IN
cord-260708-l9w5jhsw	311	8	bunyaviruses	bunyavirus	NNS
cord-260708-l9w5jhsw	311	9	and	and	CC
cord-260708-l9w5jhsw	311	10	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	311	11	(	(	-LRB-
cord-260708-l9w5jhsw	311	12	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	311	13	)	)	-RRB-
cord-260708-l9w5jhsw	311	14	:	:	:
cord-260708-l9w5jhsw	311	15	evidence	evidence	NN
cord-260708-l9w5jhsw	311	16	of	of	IN
cord-260708-l9w5jhsw	311	17	end	end	NN
cord-260708-l9w5jhsw	311	18	sequence	sequence	NN
cord-260708-l9w5jhsw	311	19	generic	generic	JJ
cord-260708-l9w5jhsw	311	20	differences	difference	NNS
cord-260708-l9w5jhsw	311	21	within	within	IN
cord-260708-l9w5jhsw	311	22	the	the	DT
cord-260708-l9w5jhsw	311	23	virus	virus	NN
cord-260708-l9w5jhsw	311	24	family	family	NN
cord-260708-l9w5jhsw	311	25	Qalyub	Qalyub	NNP
cord-260708-l9w5jhsw	311	26	virus	virus	NN
cord-260708-l9w5jhsw	311	27	,	,	,
cord-260708-l9w5jhsw	311	28	a	a	DT
cord-260708-l9w5jhsw	311	29	member	member	NN
cord-260708-l9w5jhsw	311	30	of	of	IN
cord-260708-l9w5jhsw	311	31	the	the	DT
cord-260708-l9w5jhsw	311	32	newly	newly	RB
cord-260708-l9w5jhsw	311	33	proposed	propose	VBN
cord-260708-l9w5jhsw	311	34	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	311	35	genus	genus	NN
cord-260708-l9w5jhsw	311	36	(	(	-LRB-
cord-260708-l9w5jhsw	311	37	Bunyavividae	Bunyavividae	NNP
cord-260708-l9w5jhsw	311	38	)	)	-RRB-
cord-260708-l9w5jhsw	312	1	Structural	structural	JJ
cord-260708-l9w5jhsw	312	2	characteristics	characteristic	NNS
cord-260708-l9w5jhsw	312	3	of	of	IN
cord-260708-l9w5jhsw	312	4	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	312	5	(	(	-LRB-
cord-260708-l9w5jhsw	312	6	genus	genus	NN
cord-260708-l9w5jhsw	312	7	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	312	8	,	,	,
cord-260708-l9w5jhsw	312	9	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	312	10	)	)	-RRB-
cord-260708-l9w5jhsw	312	11	Fusing	fuse	VBG
cord-260708-l9w5jhsw	312	12	structure	structure	NN
cord-260708-l9w5jhsw	312	13	and	and	CC
cord-260708-l9w5jhsw	312	14	function	function	NN
cord-260708-l9w5jhsw	312	15	:	:	:
cord-260708-l9w5jhsw	312	16	a	a	DT
cord-260708-l9w5jhsw	312	17	structural	structural	JJ
cord-260708-l9w5jhsw	312	18	view	view	NN
cord-260708-l9w5jhsw	312	19	of	of	IN
cord-260708-l9w5jhsw	312	20	the	the	DT
cord-260708-l9w5jhsw	312	21	herpesvirus	herpesvirus	NN
cord-260708-l9w5jhsw	312	22	entry	entry	NN
cord-260708-l9w5jhsw	312	23	machinery	machinery	NN
cord-260708-l9w5jhsw	312	24	Pretoria	Pretoria	NNP
cord-260708-l9w5jhsw	312	25	virus	virus	NN
cord-260708-l9w5jhsw	312	26	:	:	:
cord-260708-l9w5jhsw	312	27	a	a	DT
cord-260708-l9w5jhsw	312	28	new	new	JJ
cord-260708-l9w5jhsw	312	29	African	african	JJ
cord-260708-l9w5jhsw	312	30	agent	agent	NN
cord-260708-l9w5jhsw	312	31	in	in	IN
cord-260708-l9w5jhsw	312	32	the	the	DT
cord-260708-l9w5jhsw	312	33	tickborne	tickborne	JJ
cord-260708-l9w5jhsw	312	34	Dera	Dera	NNP
cord-260708-l9w5jhsw	312	35	Ghazi	Ghazi	NNP
cord-260708-l9w5jhsw	312	36	Khan	Khan	NNP
cord-260708-l9w5jhsw	312	37	(	(	-LRB-
cord-260708-l9w5jhsw	312	38	DGK	DGK	NNP
cord-260708-l9w5jhsw	312	39	)	)	-RRB-
cord-260708-l9w5jhsw	312	40	group	group	NN
cord-260708-l9w5jhsw	312	41	and	and	CC
cord-260708-l9w5jhsw	312	42	antigenic	antigenic	JJ
cord-260708-l9w5jhsw	312	43	relationships	relationship	NNS
cord-260708-l9w5jhsw	312	44	within	within	IN
cord-260708-l9w5jhsw	312	45	the	the	DT
cord-260708-l9w5jhsw	312	46	DGK	DGK	NNP
cord-260708-l9w5jhsw	312	47	group	group	NN
cord-260708-l9w5jhsw	312	48	Soldado	Soldado	NNP
cord-260708-l9w5jhsw	312	49	virus	virus	NN
cord-260708-l9w5jhsw	312	50	(	(	-LRB-
cord-260708-l9w5jhsw	312	51	Hughes	Hughes	NNP
cord-260708-l9w5jhsw	312	52	group	group	NN
cord-260708-l9w5jhsw	312	53	)	)	-RRB-
cord-260708-l9w5jhsw	312	54	from	from	IN
cord-260708-l9w5jhsw	312	55	Ornithodoros	Ornithodoros	NNP
cord-260708-l9w5jhsw	313	1	(	(	-LRB-
cord-260708-l9w5jhsw	313	2	Alectorobius	alectorobius	NN
cord-260708-l9w5jhsw	313	3	)	)	-RRB-
cord-260708-l9w5jhsw	313	4	capensis	capensis	NN
cord-260708-l9w5jhsw	314	1	(	(	-LRB-
cord-260708-l9w5jhsw	314	2	Ixodoidea	Ixodoidea	NNP
cord-260708-l9w5jhsw	314	3	:	:	:
cord-260708-l9w5jhsw	314	4	Argasidae	Argasidae	NNP
cord-260708-l9w5jhsw	314	5	)	)	-RRB-
cord-260708-l9w5jhsw	314	6	infesting	infest	VBG
cord-260708-l9w5jhsw	314	7	Sooty	Sooty	NNP
cord-260708-l9w5jhsw	314	8	Tern	Tern	NNP
cord-260708-l9w5jhsw	314	9	colonies	colony	NNS
cord-260708-l9w5jhsw	314	10	in	in	IN
cord-260708-l9w5jhsw	314	11	the	the	DT
cord-260708-l9w5jhsw	314	12	Seychelles	Seychelles	NNP
cord-260708-l9w5jhsw	314	13	,	,	,
cord-260708-l9w5jhsw	314	14	Indian	Indian	NNP
cord-260708-l9w5jhsw	314	15	Ocean	Ocean	NNP
cord-260708-l9w5jhsw	314	16	Kupe	Kupe	NNP
cord-260708-l9w5jhsw	314	17	virus	virus	NN
cord-260708-l9w5jhsw	314	18	,	,	,
cord-260708-l9w5jhsw	314	19	a	a	DT
cord-260708-l9w5jhsw	314	20	new	new	JJ
cord-260708-l9w5jhsw	314	21	virus	virus	NN
cord-260708-l9w5jhsw	314	22	in	in	IN
cord-260708-l9w5jhsw	314	23	the	the	DT
cord-260708-l9w5jhsw	314	24	family	family	NN
cord-260708-l9w5jhsw	314	25	bunyaviridae	bunyaviridae	NN
cord-260708-l9w5jhsw	314	26	,	,	,
cord-260708-l9w5jhsw	314	27	genus	genus	NNP
cord-260708-l9w5jhsw	314	28	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	314	29	,	,	,
cord-260708-l9w5jhsw	315	1	kenya	kenya	NNP
cord-260708-l9w5jhsw	315	2	The	the	DT
cord-260708-l9w5jhsw	315	3	C	C	NNP
cord-260708-l9w5jhsw	315	4	-	-	HYPH
cord-260708-l9w5jhsw	315	5	terminal	terminal	NN
cord-260708-l9w5jhsw	315	6	regulatory	regulatory	JJ
cord-260708-l9w5jhsw	315	7	domain	domain	NN
cord-260708-l9w5jhsw	315	8	is	be	VBZ
cord-260708-l9w5jhsw	315	9	the	the	DT
cord-260708-l9w5jhsw	315	10	RNA	RNA	NNP
cord-260708-l9w5jhsw	315	11	5'-triphosphate	5'-triphosphate	CD
cord-260708-l9w5jhsw	315	12	sensor	sensor	NN
cord-260708-l9w5jhsw	315	13	of	of	IN
cord-260708-l9w5jhsw	315	14	RIG	rig	NN
cord-260708-l9w5jhsw	315	15	-	-	:
cord-260708-l9w5jhsw	315	16	I	I	NNP
cord-260708-l9w5jhsw	315	17	Isolation	isolation	NN
cord-260708-l9w5jhsw	315	18	of	of	IN
cord-260708-l9w5jhsw	315	19	Ganjam	Ganjam	NNP
cord-260708-l9w5jhsw	315	20	virus	virus	NN
cord-260708-l9w5jhsw	315	21	from	from	IN
cord-260708-l9w5jhsw	315	22	a	a	DT
cord-260708-l9w5jhsw	315	23	human	human	JJ
cord-260708-l9w5jhsw	315	24	case	case	NN
cord-260708-l9w5jhsw	315	25	of	of	IN
cord-260708-l9w5jhsw	315	26	febrile	febrile	JJ
cord-260708-l9w5jhsw	315	27	illness	illness	NN
cord-260708-l9w5jhsw	315	28	:	:	:
cord-260708-l9w5jhsw	315	29	a	a	DT
cord-260708-l9w5jhsw	315	30	report	report	NN
cord-260708-l9w5jhsw	315	31	of	of	IN
cord-260708-l9w5jhsw	315	32	a	a	DT
cord-260708-l9w5jhsw	315	33	laboratory	laboratory	NN
cord-260708-l9w5jhsw	315	34	infection	infection	NN
cord-260708-l9w5jhsw	315	35	and	and	CC
cord-260708-l9w5jhsw	315	36	serological	serological	JJ
cord-260708-l9w5jhsw	315	37	survey	survey	NN
cord-260708-l9w5jhsw	315	38	of	of	IN
cord-260708-l9w5jhsw	315	39	human	human	NNP
cord-260708-l9w5jhsw	315	40	sera	sera	NNP
cord-260708-l9w5jhsw	315	41	from	from	IN
cord-260708-l9w5jhsw	315	42	three	three	CD
cord-260708-l9w5jhsw	315	43	different	different	JJ
cord-260708-l9w5jhsw	315	44	states	state	NNS
cord-260708-l9w5jhsw	315	45	of	of	IN
cord-260708-l9w5jhsw	315	46	India	India	NNP
cord-260708-l9w5jhsw	315	47	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	315	48	virus	virus	NN
cord-260708-l9w5jhsw	315	49	:	:	:
cord-260708-l9w5jhsw	315	50	a	a	DT
cord-260708-l9w5jhsw	315	51	tick	tick	VB
cord-260708-l9w5jhsw	315	52	-	-	HYPH
cord-260708-l9w5jhsw	315	53	borne	bear	VBN
cord-260708-l9w5jhsw	315	54	arbovirus	arbovirus	NN
cord-260708-l9w5jhsw	315	55	from	from	IN
cord-260708-l9w5jhsw	315	56	Nigeria	Nigeria	NNP
cord-260708-l9w5jhsw	316	1	The	the	DT
cord-260708-l9w5jhsw	316	2	serological	serological	JJ
cord-260708-l9w5jhsw	316	3	relationships	relationship	NNS
cord-260708-l9w5jhsw	316	4	of	of	IN
cord-260708-l9w5jhsw	316	5	Nairobi	Nairobi	NNP
cord-260708-l9w5jhsw	316	6	sheep	sheep	NN
cord-260708-l9w5jhsw	316	7	disease	disease	NN
cord-260708-l9w5jhsw	316	8	virus	virus	NN
cord-260708-l9w5jhsw	316	9	Tomato	Tomato	NNP
cord-260708-l9w5jhsw	316	10	spotted	spot	VBD
cord-260708-l9w5jhsw	316	11	wilt	wilt	NN
cord-260708-l9w5jhsw	316	12	virus	virus	NN
cord-260708-l9w5jhsw	316	13	L	L	NNP
cord-260708-l9w5jhsw	316	14	RNA	RNA	NNP
cord-260708-l9w5jhsw	316	15	encodes	encode	VBZ
cord-260708-l9w5jhsw	316	16	a	a	DT
cord-260708-l9w5jhsw	316	17	putative	putative	JJ
cord-260708-l9w5jhsw	316	18	RNA	rna	NN
cord-260708-l9w5jhsw	316	19	polymerase	polymerase	NN
cord-260708-l9w5jhsw	316	20	Characterization	characterization	NN
cord-260708-l9w5jhsw	316	21	of	of	IN
cord-260708-l9w5jhsw	316	22	a	a	DT
cord-260708-l9w5jhsw	316	23	100-kilodalton	100-kilodalton	CD
cord-260708-l9w5jhsw	316	24	binding	bind	VBG
cord-260708-l9w5jhsw	316	25	protein	protein	NN
cord-260708-l9w5jhsw	316	26	for	for	IN
cord-260708-l9w5jhsw	316	27	the	the	DT
cord-260708-l9w5jhsw	316	28	six	six	CD
cord-260708-l9w5jhsw	316	29	serotypes	serotype	NNS
cord-260708-l9w5jhsw	316	30	of	of	IN
cord-260708-l9w5jhsw	316	31	coxsackie	coxsackie	NNS
cord-260708-l9w5jhsw	316	32	B	B	NNP
cord-260708-l9w5jhsw	316	33	viruses	virus	NNS
cord-260708-l9w5jhsw	317	1	An	an	DT
cord-260708-l9w5jhsw	317	2	attempt	attempt	NN
cord-260708-l9w5jhsw	317	3	to	to	TO
cord-260708-l9w5jhsw	317	4	unify	unify	VB
cord-260708-l9w5jhsw	317	5	the	the	DT
cord-260708-l9w5jhsw	317	6	structure	structure	NN
cord-260708-l9w5jhsw	317	7	of	of	IN
cord-260708-l9w5jhsw	317	8	polymerases	polymerase	NNS
cord-260708-l9w5jhsw	317	9	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	317	10	-	-	HYPH
cord-260708-l9w5jhsw	317	11	Congo	Congo	NNP
cord-260708-l9w5jhsw	317	12	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	317	13	fever	fever	NN
cord-260708-l9w5jhsw	317	14	virus	virus	NN
cord-260708-l9w5jhsw	317	15	genomics	genomic	NNS
cord-260708-l9w5jhsw	317	16	and	and	CC
cord-260708-l9w5jhsw	317	17	global	global	JJ
cord-260708-l9w5jhsw	317	18	diversity	diversity	NN
cord-260708-l9w5jhsw	318	1	The	the	DT
cord-260708-l9w5jhsw	318	2	cap	cap	NN
cord-260708-l9w5jhsw	318	3	-	-	HYPH
cord-260708-l9w5jhsw	318	4	snatching	snatch	VBG
cord-260708-l9w5jhsw	318	5	endonuclease	endonuclease	NN
cord-260708-l9w5jhsw	318	6	of	of	IN
cord-260708-l9w5jhsw	318	7	influenza	influenza	NN
cord-260708-l9w5jhsw	318	8	virus	virus	NN
cord-260708-l9w5jhsw	318	9	polymerase	polymerase	NN
cord-260708-l9w5jhsw	318	10	resides	reside	VBZ
cord-260708-l9w5jhsw	318	11	in	in	IN
cord-260708-l9w5jhsw	318	12	the	the	DT
cord-260708-l9w5jhsw	318	13	PA	PA	NNP
cord-260708-l9w5jhsw	318	14	subunit	subunit	NN
cord-260708-l9w5jhsw	318	15	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	318	16	-	-	HYPH
cord-260708-l9w5jhsw	318	17	Congo	Congo	NNP
cord-260708-l9w5jhsw	318	18	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	318	19	fever	fever	NN
cord-260708-l9w5jhsw	318	20	in	in	IN
cord-260708-l9w5jhsw	319	1	Kosovo	Kosovo	NNP
cord-260708-l9w5jhsw	319	2	First	First	NNP
cord-260708-l9w5jhsw	319	3	documentation	documentation	NN
cord-260708-l9w5jhsw	319	4	of	of	IN
cord-260708-l9w5jhsw	319	5	human	human	JJ
cord-260708-l9w5jhsw	319	6	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	319	7	-	-	HYPH
cord-260708-l9w5jhsw	319	8	Congo	Congo	NNP
cord-260708-l9w5jhsw	319	9	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	319	10	fever	fever	NN
cord-260708-l9w5jhsw	319	11	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	319	12	-	-	HYPH
cord-260708-l9w5jhsw	319	13	Congo	Congo	NNP
cord-260708-l9w5jhsw	319	14	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	319	15	fever	fever	NN
cord-260708-l9w5jhsw	319	16	virus	virus	NN
cord-260708-l9w5jhsw	319	17	infection	infection	NN
cord-260708-l9w5jhsw	319	18	in	in	IN
cord-260708-l9w5jhsw	319	19	the	the	DT
cord-260708-l9w5jhsw	319	20	western	western	JJ
cord-260708-l9w5jhsw	319	21	province	province	NN
cord-260708-l9w5jhsw	319	22	of	of	IN
cord-260708-l9w5jhsw	319	23	Saudi	Saudi	NNP
cord-260708-l9w5jhsw	319	24	Arabia	Arabia	NNP
cord-260708-l9w5jhsw	319	25	Biosynthesis	Biosynthesis	NNP
cord-260708-l9w5jhsw	319	26	and	and	CC
cord-260708-l9w5jhsw	319	27	cellular	cellular	JJ
cord-260708-l9w5jhsw	319	28	trafficking	trafficking	NN
cord-260708-l9w5jhsw	319	29	of	of	IN
cord-260708-l9w5jhsw	319	30	the	the	DT
cord-260708-l9w5jhsw	319	31	convertase	convertase	NN
cord-260708-l9w5jhsw	319	32	SKI-1	SKI-1	NNP
cord-260708-l9w5jhsw	319	33	/	/	SYM
cord-260708-l9w5jhsw	319	34	S1P	s1p	NN
cord-260708-l9w5jhsw	320	1	:	:	:
cord-260708-l9w5jhsw	320	2	ectodomain	ectodomain	NNP
cord-260708-l9w5jhsw	320	3	shedding	shedding	NN
cord-260708-l9w5jhsw	320	4	requires	require	VBZ
cord-260708-l9w5jhsw	320	5	SKI-1	SKI-1	NNP
cord-260708-l9w5jhsw	320	6	activity	activity	NN
cord-260708-l9w5jhsw	320	7	Congo	Congo	NNP
cord-260708-l9w5jhsw	320	8	/	/	SYM
cord-260708-l9w5jhsw	320	9	Crimean	crimean	JJ
cord-260708-l9w5jhsw	320	10	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	320	11	fever	fever	NN
cord-260708-l9w5jhsw	320	12	virus	virus	NN
cord-260708-l9w5jhsw	320	13	from	from	IN
cord-260708-l9w5jhsw	320	14	Iraq	Iraq	NNP
cord-260708-l9w5jhsw	320	15	1979	1979	CD
cord-260708-l9w5jhsw	320	16	:	:	:
cord-260708-l9w5jhsw	321	1	I.	I.	NNP
cord-260708-l9w5jhsw	321	2	Morphology	morphology	NN
cord-260708-l9w5jhsw	321	3	in	in	IN
cord-260708-l9w5jhsw	321	4	BHK21	BHK21	NNP
cord-260708-l9w5jhsw	321	5	cells	cell	VBZ
cord-260708-l9w5jhsw	321	6	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	321	7	-	-	HYPH
cord-260708-l9w5jhsw	321	8	Congo	Congo	NNP
cord-260708-l9w5jhsw	321	9	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	321	10	fever	fever	NN
cord-260708-l9w5jhsw	321	11	N	n	NN
cord-260708-l9w5jhsw	321	12	-	-	HYPH
cord-260708-l9w5jhsw	321	13	linked	link	VBN
cord-260708-l9w5jhsw	321	14	glycosylation	glycosylation	NN
cord-260708-l9w5jhsw	321	15	of	of	IN
cord-260708-l9w5jhsw	321	16	Gn	Gn	NNP
cord-260708-l9w5jhsw	321	17	(	(	-LRB-
cord-260708-l9w5jhsw	321	18	but	but	CC
cord-260708-l9w5jhsw	321	19	not	not	RB
cord-260708-l9w5jhsw	321	20	Gc	Gc	NNP
cord-260708-l9w5jhsw	321	21	)	)	-RRB-
cord-260708-l9w5jhsw	321	22	is	be	VBZ
cord-260708-l9w5jhsw	321	23	important	important	JJ
cord-260708-l9w5jhsw	321	24	for	for	IN
cord-260708-l9w5jhsw	321	25	Crimean	crimean	JJ
cord-260708-l9w5jhsw	321	26	Congo	Congo	NNP
cord-260708-l9w5jhsw	321	27	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	321	28	fever	fever	NN
cord-260708-l9w5jhsw	321	29	virus	virus	NN
cord-260708-l9w5jhsw	321	30	glycoprotein	glycoprotein	NN
cord-260708-l9w5jhsw	321	31	localization	localization	NN
cord-260708-l9w5jhsw	321	32	and	and	CC
cord-260708-l9w5jhsw	321	33	transport	transport	NN
cord-260708-l9w5jhsw	321	34	Molecular	molecular	JJ
cord-260708-l9w5jhsw	321	35	biology	biology	NN
cord-260708-l9w5jhsw	321	36	of	of	IN
cord-260708-l9w5jhsw	321	37	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	321	38	1261	1261	CD
cord-260708-l9w5jhsw	322	1	The	the	DT
cord-260708-l9w5jhsw	322	2	Hantavirus	Hantavirus	NNP
cord-260708-l9w5jhsw	322	3	Glycoprotein	Glycoprotein	NNP
cord-260708-l9w5jhsw	322	4	G1	G1	NNP
cord-260708-l9w5jhsw	322	5	Tail	Tail	NNP
cord-260708-l9w5jhsw	322	6	Contains	contain	VBZ
cord-260708-l9w5jhsw	322	7	Dual	dual	JJ
cord-260708-l9w5jhsw	322	8	CCHC	cchc	NN
cord-260708-l9w5jhsw	322	9	-	-	HYPH
cord-260708-l9w5jhsw	322	10	type	type	NN
cord-260708-l9w5jhsw	322	11	Classical	Classical	NNP
cord-260708-l9w5jhsw	322	12	Zinc	Zinc	NNP
cord-260708-l9w5jhsw	322	13	Fingers	Fingers	NNP
cord-260708-l9w5jhsw	322	14	Structural	structural	JJ
cord-260708-l9w5jhsw	322	15	characterization	characterization	NN
cord-260708-l9w5jhsw	322	16	of	of	IN
cord-260708-l9w5jhsw	322	17	the	the	DT
cord-260708-l9w5jhsw	322	18	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	322	19	-	-	HYPH
cord-260708-l9w5jhsw	322	20	Congo	Congo	NNP
cord-260708-l9w5jhsw	322	21	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	322	22	fever	fever	NN
cord-260708-l9w5jhsw	322	23	virus	virus	NN
cord-260708-l9w5jhsw	323	1	Gn	Gn	NNP
cord-260708-l9w5jhsw	323	2	tail	tail	NN
cord-260708-l9w5jhsw	323	3	provides	provide	VBZ
cord-260708-l9w5jhsw	323	4	insight	insight	NN
cord-260708-l9w5jhsw	323	5	into	into	IN
cord-260708-l9w5jhsw	324	1	virus	virus	NN
cord-260708-l9w5jhsw	324	2	assembly	assembly	NNP
cord-260708-l9w5jhsw	324	3	A	a	DT
cord-260708-l9w5jhsw	324	4	SELEX	SELEX	NNP
cord-260708-l9w5jhsw	324	5	-	-	HYPH
cord-260708-l9w5jhsw	324	6	screened	screen	VBN
cord-260708-l9w5jhsw	324	7	aptamer	aptamer	NNP
cord-260708-l9w5jhsw	324	8	of	of	IN
cord-260708-l9w5jhsw	324	9	human	human	JJ
cord-260708-l9w5jhsw	324	10	hepatitis	hepatitis	NNP
cord-260708-l9w5jhsw	324	11	B	B	NNP
cord-260708-l9w5jhsw	324	12	virus	virus	NN
cord-260708-l9w5jhsw	324	13	RNA	rna	NN
cord-260708-l9w5jhsw	324	14	encapsidation	encapsidation	NN
cord-260708-l9w5jhsw	324	15	signal	signal	NN
cord-260708-l9w5jhsw	324	16	suppresses	suppress	VBZ
cord-260708-l9w5jhsw	324	17	viral	viral	JJ
cord-260708-l9w5jhsw	324	18	replication	replication	NN
cord-260708-l9w5jhsw	325	1	The	the	DT
cord-260708-l9w5jhsw	325	2	ISG56	ISG56	NNP
cord-260708-l9w5jhsw	325	3	/	/	SYM
cord-260708-l9w5jhsw	325	4	IFIT1	ifit1	JJ
cord-260708-l9w5jhsw	325	5	gene	gene	NN
cord-260708-l9w5jhsw	325	6	family	family	NN
cord-260708-l9w5jhsw	326	1	The	the	DT
cord-260708-l9w5jhsw	326	2	hexamer	hexamer	JJ
cord-260708-l9w5jhsw	326	3	structure	structure	NN
cord-260708-l9w5jhsw	326	4	of	of	IN
cord-260708-l9w5jhsw	326	5	Rift	Rift	NNP
cord-260708-l9w5jhsw	326	6	Valley	Valley	NNP
cord-260708-l9w5jhsw	326	7	fever	fever	NN
cord-260708-l9w5jhsw	326	8	virus	virus	NN
cord-260708-l9w5jhsw	326	9	nucleoprotein	nucleoprotein	NNP
cord-260708-l9w5jhsw	326	10	suggests	suggest	VBZ
cord-260708-l9w5jhsw	326	11	a	a	DT
cord-260708-l9w5jhsw	326	12	mechanism	mechanism	NN
cord-260708-l9w5jhsw	326	13	for	for	IN
cord-260708-l9w5jhsw	326	14	its	-PRON-	PRP$
cord-260708-l9w5jhsw	326	15	assembly	assembly	NN
cord-260708-l9w5jhsw	326	16	into	into	IN
cord-260708-l9w5jhsw	326	17	ribonucleoprotein	ribonucleoprotein	NN
cord-260708-l9w5jhsw	326	18	complexes	complex	NNS
cord-260708-l9w5jhsw	326	19	Reverse	reverse	VBP
cord-260708-l9w5jhsw	326	20	genetics	genetic	NNS
cord-260708-l9w5jhsw	326	21	system	system	NN
cord-260708-l9w5jhsw	326	22	for	for	IN
cord-260708-l9w5jhsw	326	23	Uukuniemi	Uukuniemi	NNP
cord-260708-l9w5jhsw	326	24	virus	virus	NN
cord-260708-l9w5jhsw	326	25	(	(	-LRB-
cord-260708-l9w5jhsw	326	26	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	326	27	)	)	-RRB-
cord-260708-l9w5jhsw	326	28	:	:	:
cord-260708-l9w5jhsw	327	1	RNA	RNA	NNP
cord-260708-l9w5jhsw	327	2	polymerase	polymerase	NN
cord-260708-l9w5jhsw	327	3	I	i	NN
cord-260708-l9w5jhsw	327	4	-	-	HYPH
cord-260708-l9w5jhsw	327	5	catalyzed	catalyze	VBN
cord-260708-l9w5jhsw	327	6	expression	expression	NN
cord-260708-l9w5jhsw	327	7	of	of	IN
cord-260708-l9w5jhsw	327	8	chimeric	chimeric	JJ
cord-260708-l9w5jhsw	327	9	viral	viral	JJ
cord-260708-l9w5jhsw	327	10	RNAs	rna	NNS
cord-260708-l9w5jhsw	327	11	Mutational	Mutational	NNP
cord-260708-l9w5jhsw	327	12	analysis	analysis	NN
cord-260708-l9w5jhsw	327	13	of	of	IN
cord-260708-l9w5jhsw	327	14	the	the	DT
cord-260708-l9w5jhsw	327	15	Uukuniemi	Uukuniemi	NNP
cord-260708-l9w5jhsw	327	16	virus	virus	NN
cord-260708-l9w5jhsw	327	17	(	(	-LRB-
cord-260708-l9w5jhsw	327	18	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	327	19	family	family	NN
cord-260708-l9w5jhsw	327	20	)	)	-RRB-
cord-260708-l9w5jhsw	327	21	promoter	promoter	NN
cord-260708-l9w5jhsw	327	22	reveals	reveal	VBZ
cord-260708-l9w5jhsw	327	23	two	two	CD
cord-260708-l9w5jhsw	327	24	elements	element	NNS
cord-260708-l9w5jhsw	327	25	of	of	IN
cord-260708-l9w5jhsw	327	26	functional	functional	JJ
cord-260708-l9w5jhsw	327	27	importance	importance	NN
cord-260708-l9w5jhsw	327	28	Reverse	reverse	NN
cord-260708-l9w5jhsw	327	29	genetics	genetics	NN
cord-260708-l9w5jhsw	327	30	for	for	IN
cord-260708-l9w5jhsw	327	31	crimean	crimean	NNP
cord-260708-l9w5jhsw	327	32	-	-	HYPH
cord-260708-l9w5jhsw	327	33	congo	congo	NNP
cord-260708-l9w5jhsw	327	34	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	327	35	fever	fever	NN
cord-260708-l9w5jhsw	327	36	virus	virus	NN
cord-260708-l9w5jhsw	327	37	Structural	structural	JJ
cord-260708-l9w5jhsw	327	38	polypeptides	polypeptide	NNS
cord-260708-l9w5jhsw	327	39	of	of	IN
cord-260708-l9w5jhsw	327	40	Hazara	hazara	JJ
cord-260708-l9w5jhsw	327	41	virus	virus	NN
cord-260708-l9w5jhsw	327	42	Ovarian	ovarian	JJ
cord-260708-l9w5jhsw	327	43	tumor	tumor	NN
cord-260708-l9w5jhsw	327	44	domain	domain	NN
cord-260708-l9w5jhsw	327	45	-	-	HYPH
cord-260708-l9w5jhsw	327	46	containing	contain	VBG
cord-260708-l9w5jhsw	327	47	viral	viral	JJ
cord-260708-l9w5jhsw	327	48	proteases	protease	NNS
cord-260708-l9w5jhsw	327	49	evade	evade	VBP
cord-260708-l9w5jhsw	327	50	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	327	51	-	-	:
cord-260708-l9w5jhsw	327	52	and	and	CC
cord-260708-l9w5jhsw	327	53	ISG15-dependent	isg15-dependent	CD
cord-260708-l9w5jhsw	327	54	innate	innate	JJ
cord-260708-l9w5jhsw	327	55	immune	immune	JJ
cord-260708-l9w5jhsw	327	56	responses	response	NNS
cord-260708-l9w5jhsw	327	57	RING	ring	NN
cord-260708-l9w5jhsw	327	58	-	-	HYPH
cord-260708-l9w5jhsw	327	59	finger	finger	NN
cord-260708-l9w5jhsw	327	60	E3	e3	NN
cord-260708-l9w5jhsw	327	61	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	327	62	ligase	ligase	NN
cord-260708-l9w5jhsw	327	63	is	be	VBZ
cord-260708-l9w5jhsw	327	64	essential	essential	JJ
cord-260708-l9w5jhsw	327	65	for	for	IN
cord-260708-l9w5jhsw	327	66	RIG	rig	NN
cord-260708-l9w5jhsw	327	67	-	-	HYPH
cord-260708-l9w5jhsw	327	68	I	i	NN
cord-260708-l9w5jhsw	327	69	-	-	HYPH
cord-260708-l9w5jhsw	327	70	mediated	mediate	VBN
cord-260708-l9w5jhsw	327	71	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	327	72	activity	activity	NN
cord-260708-l9w5jhsw	328	1	Sticky	sticky	JJ
cord-260708-l9w5jhsw	328	2	fingers	finger	NNS
cord-260708-l9w5jhsw	328	3	:	:	:
cord-260708-l9w5jhsw	328	4	zinc	zinc	NN
cord-260708-l9w5jhsw	328	5	-	-	HYPH
cord-260708-l9w5jhsw	328	6	fingers	finger	NNS
cord-260708-l9w5jhsw	328	7	as	as	IN
cord-260708-l9w5jhsw	328	8	protein	protein	NN
cord-260708-l9w5jhsw	328	9	-	-	HYPH
cord-260708-l9w5jhsw	328	10	recognition	recognition	NN
cord-260708-l9w5jhsw	328	11	motifs	motif	NNS
cord-260708-l9w5jhsw	328	12	Type	type	NN
cord-260708-l9w5jhsw	328	13	1	1	CD
cord-260708-l9w5jhsw	328	14	interferons	interferon	NNS
cord-260708-l9w5jhsw	328	15	and	and	CC
cord-260708-l9w5jhsw	328	16	the	the	DT
cord-260708-l9w5jhsw	328	17	virus	virus	NN
cord-260708-l9w5jhsw	328	18	-	-	HYPH
cord-260708-l9w5jhsw	328	19	host	host	NN
cord-260708-l9w5jhsw	328	20	relationship	relationship	NN
cord-260708-l9w5jhsw	329	1	:	:	:
cord-260708-l9w5jhsw	329	2	a	a	DT
cord-260708-l9w5jhsw	329	3	lesson	lesson	NN
cord-260708-l9w5jhsw	329	4	in	in	IN
cord-260708-l9w5jhsw	329	5	detente	detente	NN
cord-260708-l9w5jhsw	330	1	The	the	DT
cord-260708-l9w5jhsw	330	2	5	5	CD
cord-260708-l9w5jhsw	330	3	'	'	POS
cord-260708-l9w5jhsw	330	4	ends	end	NNS
cord-260708-l9w5jhsw	330	5	of	of	IN
cord-260708-l9w5jhsw	330	6	Hantaan	Hantaan	NNP
cord-260708-l9w5jhsw	330	7	virus	virus	NN
cord-260708-l9w5jhsw	330	8	(	(	-LRB-
cord-260708-l9w5jhsw	330	9	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	330	10	)	)	-RRB-
cord-260708-l9w5jhsw	330	11	RNAs	rna	NNS
cord-260708-l9w5jhsw	330	12	suggest	suggest	VBP
cord-260708-l9w5jhsw	330	13	a	a	DT
cord-260708-l9w5jhsw	330	14	prime	prime	JJ
cord-260708-l9w5jhsw	330	15	-	-	HYPH
cord-260708-l9w5jhsw	330	16	and	and	CC
cord-260708-l9w5jhsw	330	17	-	-	HYPH
cord-260708-l9w5jhsw	330	18	realign	realign	VB
cord-260708-l9w5jhsw	330	19	mechanism	mechanism	NN
cord-260708-l9w5jhsw	330	20	for	for	IN
cord-260708-l9w5jhsw	330	21	the	the	DT
cord-260708-l9w5jhsw	330	22	initiation	initiation	NN
cord-260708-l9w5jhsw	330	23	of	of	IN
cord-260708-l9w5jhsw	330	24	RNA	RNA	NNP
cord-260708-l9w5jhsw	330	25	synthesis	synthesis	NN
cord-260708-l9w5jhsw	330	26	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	330	27	-	-	HYPH
cord-260708-l9w5jhsw	330	28	Congo	Congo	NNP
cord-260708-l9w5jhsw	330	29	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	330	30	fever	fever	NN
cord-260708-l9w5jhsw	330	31	virus	virus	NN
cord-260708-l9w5jhsw	330	32	utilizes	utilize	VBZ
cord-260708-l9w5jhsw	330	33	a	a	DT
cord-260708-l9w5jhsw	330	34	clathrin	clathrin	NN
cord-260708-l9w5jhsw	330	35	-	-	:
cord-260708-l9w5jhsw	330	36	and	and	CC
cord-260708-l9w5jhsw	330	37	early	early	JJ
cord-260708-l9w5jhsw	330	38	endosome	endosome	NN
cord-260708-l9w5jhsw	330	39	-	-	HYPH
cord-260708-l9w5jhsw	330	40	dependent	dependent	JJ
cord-260708-l9w5jhsw	330	41	entry	entry	NN
cord-260708-l9w5jhsw	330	42	pathway	pathway	NN
cord-260708-l9w5jhsw	330	43	Proteomic	Proteomic	NNP
cord-260708-l9w5jhsw	330	44	identification	identification	NN
cord-260708-l9w5jhsw	330	45	of	of	IN
cord-260708-l9w5jhsw	330	46	proteins	protein	NNS
cord-260708-l9w5jhsw	330	47	conjugated	conjugate	VBN
cord-260708-l9w5jhsw	330	48	to	to	IN
cord-260708-l9w5jhsw	330	49	ISG15	isg15	NN
cord-260708-l9w5jhsw	330	50	in	in	IN
cord-260708-l9w5jhsw	330	51	mouse	mouse	NN
cord-260708-l9w5jhsw	330	52	and	and	CC
cord-260708-l9w5jhsw	330	53	human	human	NN
cord-260708-l9w5jhsw	330	54	cells	cell	NNS
cord-260708-l9w5jhsw	330	55	Immunofluorescence	Immunofluorescence	NNP
cord-260708-l9w5jhsw	330	56	studies	study	NNS
cord-260708-l9w5jhsw	330	57	on	on	IN
cord-260708-l9w5jhsw	330	58	the	the	DT
cord-260708-l9w5jhsw	330	59	antigenic	antigenic	JJ
cord-260708-l9w5jhsw	330	60	interrelationships	interrelationship	NNS
cord-260708-l9w5jhsw	330	61	of	of	IN
cord-260708-l9w5jhsw	330	62	the	the	DT
cord-260708-l9w5jhsw	330	63	Hughes	Hughes	NNP
cord-260708-l9w5jhsw	330	64	virus	virus	NN
cord-260708-l9w5jhsw	330	65	serogroup	serogroup	NN
cord-260708-l9w5jhsw	330	66	(	(	-LRB-
cord-260708-l9w5jhsw	330	67	genus	genus	NN
cord-260708-l9w5jhsw	330	68	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	330	69	)	)	-RRB-
cord-260708-l9w5jhsw	330	70	and	and	CC
cord-260708-l9w5jhsw	330	71	identification	identification	NN
cord-260708-l9w5jhsw	330	72	of	of	IN
cord-260708-l9w5jhsw	330	73	a	a	DT
cord-260708-l9w5jhsw	330	74	new	new	JJ
cord-260708-l9w5jhsw	330	75	strain	strain	NN
cord-260708-l9w5jhsw	330	76	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	330	77	-	-	HYPH
cord-260708-l9w5jhsw	330	78	Congo	Congo	NNP
cord-260708-l9w5jhsw	330	79	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	330	80	fever	fever	NN
cord-260708-l9w5jhsw	330	81	virus	virus	NN
cord-260708-l9w5jhsw	330	82	nucleoprotein	nucleoprotein	NNP
cord-260708-l9w5jhsw	330	83	reveals	reveal	VBZ
cord-260708-l9w5jhsw	330	84	endonuclease	endonuclease	NN
cord-260708-l9w5jhsw	330	85	activity	activity	NN
cord-260708-l9w5jhsw	330	86	in	in	IN
cord-260708-l9w5jhsw	330	87	bunyaviruses	bunyaviruses	NNP
cord-260708-l9w5jhsw	330	88	Processing	Processing	NNP
cord-260708-l9w5jhsw	330	89	of	of	IN
cord-260708-l9w5jhsw	330	90	genome	genome	NN
cord-260708-l9w5jhsw	330	91	5	5	CD
cord-260708-l9w5jhsw	330	92	'	'	NN
cord-260708-l9w5jhsw	330	93	termini	termini	NNP
cord-260708-l9w5jhsw	330	94	as	as	IN
cord-260708-l9w5jhsw	330	95	a	a	DT
cord-260708-l9w5jhsw	330	96	strategy	strategy	NN
cord-260708-l9w5jhsw	330	97	of	of	IN
cord-260708-l9w5jhsw	330	98	negative	negative	JJ
cord-260708-l9w5jhsw	330	99	-	-	HYPH
cord-260708-l9w5jhsw	330	100	strand	strand	NN
cord-260708-l9w5jhsw	330	101	RNA	RNA	NNP
cord-260708-l9w5jhsw	330	102	viruses	virus	NNS
cord-260708-l9w5jhsw	330	103	to	to	TO
cord-260708-l9w5jhsw	330	104	avoid	avoid	VB
cord-260708-l9w5jhsw	330	105	RIG	rig	NN
cord-260708-l9w5jhsw	330	106	-	-	HYPH
cord-260708-l9w5jhsw	330	107	I	i	NN
cord-260708-l9w5jhsw	330	108	-	-	HYPH
cord-260708-l9w5jhsw	330	109	dependent	dependent	JJ
cord-260708-l9w5jhsw	330	110	interferon	interferon	NN
cord-260708-l9w5jhsw	330	111	induction	induction	NN
cord-260708-l9w5jhsw	330	112	Structure	Structure	NNP
cord-260708-l9w5jhsw	330	113	of	of	IN
cord-260708-l9w5jhsw	330	114	the	the	DT
cord-260708-l9w5jhsw	330	115	Lassa	Lassa	NNP
cord-260708-l9w5jhsw	330	116	virus	virus	NN
cord-260708-l9w5jhsw	330	117	nucleoprotein	nucleoprotein	NNP
cord-260708-l9w5jhsw	330	118	reveals	reveal	VBZ
cord-260708-l9w5jhsw	330	119	a	a	DT
cord-260708-l9w5jhsw	330	120	dsRNA	dsrna	JJ
cord-260708-l9w5jhsw	330	121	-	-	HYPH
cord-260708-l9w5jhsw	330	122	specific	specific	JJ
cord-260708-l9w5jhsw	330	123	3	3	CD
cord-260708-l9w5jhsw	330	124	'	'	''
cord-260708-l9w5jhsw	330	125	to	to	IN
cord-260708-l9w5jhsw	330	126	5	5	CD
cord-260708-l9w5jhsw	330	127	'	'	''
cord-260708-l9w5jhsw	330	128	exonuclease	exonuclease	NN
cord-260708-l9w5jhsw	330	129	activity	activity	NN
cord-260708-l9w5jhsw	330	130	essential	essential	JJ
cord-260708-l9w5jhsw	330	131	for	for	IN
cord-260708-l9w5jhsw	330	132	immune	immune	JJ
cord-260708-l9w5jhsw	330	133	suppression	suppression	NN
cord-260708-l9w5jhsw	330	134	Crystal	Crystal	NNP
cord-260708-l9w5jhsw	330	135	structure	structure	NN
cord-260708-l9w5jhsw	330	136	of	of	IN
cord-260708-l9w5jhsw	330	137	the	the	DT
cord-260708-l9w5jhsw	330	138	Lassa	Lassa	NNP
cord-260708-l9w5jhsw	330	139	virus	virus	NN
cord-260708-l9w5jhsw	330	140	nucleoprotein	nucleoprotein	NNP
cord-260708-l9w5jhsw	330	141	-	-	HYPH
cord-260708-l9w5jhsw	330	142	RNA	RNA	NNP
cord-260708-l9w5jhsw	330	143	complex	complex	NN
cord-260708-l9w5jhsw	330	144	reveals	reveal	VBZ
cord-260708-l9w5jhsw	330	145	a	a	DT
cord-260708-l9w5jhsw	330	146	gating	gating	NN
cord-260708-l9w5jhsw	330	147	mechanism	mechanism	NN
cord-260708-l9w5jhsw	330	148	for	for	IN
cord-260708-l9w5jhsw	330	149	RNA	RNA	NNP
cord-260708-l9w5jhsw	330	150	binding	bind	VBG
cord-260708-l9w5jhsw	330	151	Lectins	Lectins	NNP
cord-260708-l9w5jhsw	330	152	and	and	CC
cord-260708-l9w5jhsw	330	153	traffic	traffic	NN
cord-260708-l9w5jhsw	330	154	in	in	IN
cord-260708-l9w5jhsw	330	155	the	the	DT
cord-260708-l9w5jhsw	330	156	secretory	secretory	JJ
cord-260708-l9w5jhsw	330	157	pathway	pathway	NN
cord-260708-l9w5jhsw	330	158	Intracellular	Intracellular	NNP
cord-260708-l9w5jhsw	330	159	functions	function	NNS
cord-260708-l9w5jhsw	330	160	of	of	IN
cord-260708-l9w5jhsw	330	161	N	n	CD
cord-260708-l9w5jhsw	330	162	-	-	HYPH
cord-260708-l9w5jhsw	330	163	linked	link	VBN
cord-260708-l9w5jhsw	330	164	glycans	glycan	NNS
cord-260708-l9w5jhsw	330	165	A	a	DT
cord-260708-l9w5jhsw	330	166	multifunctional	multifunctional	JJ
cord-260708-l9w5jhsw	330	167	shuttling	shuttle	VBG
cord-260708-l9w5jhsw	330	168	protein	protein	NN
cord-260708-l9w5jhsw	330	169	nucleolin	nucleolin	NNP
cord-260708-l9w5jhsw	330	170	is	be	VBZ
cord-260708-l9w5jhsw	330	171	a	a	DT
cord-260708-l9w5jhsw	330	172	macrophage	macrophage	NN
cord-260708-l9w5jhsw	330	173	receptor	receptor	NN
cord-260708-l9w5jhsw	330	174	for	for	IN
cord-260708-l9w5jhsw	330	175	apoptotic	apoptotic	JJ
cord-260708-l9w5jhsw	330	176	cells	cell	NNS
cord-260708-l9w5jhsw	331	1	Inhibition	inhibition	NN
cord-260708-l9w5jhsw	331	2	of	of	IN
cord-260708-l9w5jhsw	331	3	interferon	interferon	NN
cord-260708-l9w5jhsw	331	4	induction	induction	NN
cord-260708-l9w5jhsw	331	5	and	and	CC
cord-260708-l9w5jhsw	331	6	action	action	NN
cord-260708-l9w5jhsw	331	7	by	by	IN
cord-260708-l9w5jhsw	331	8	the	the	DT
cord-260708-l9w5jhsw	331	9	nairovirus	nairovirus	JJ
cord-260708-l9w5jhsw	331	10	Nairobi	Nairobi	NNP
cord-260708-l9w5jhsw	331	11	sheep	sheep	NN
cord-260708-l9w5jhsw	331	12	disease	disease	NN
cord-260708-l9w5jhsw	331	13	virus	virus	NN
cord-260708-l9w5jhsw	331	14	/	/	SYM
cord-260708-l9w5jhsw	331	15	Ganjam	Ganjam	NNP
cord-260708-l9w5jhsw	331	16	virus	virus	NN
cord-260708-l9w5jhsw	331	17	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	331	18	-	-	HYPH
cord-260708-l9w5jhsw	331	19	Congo	Congo	NNP
cord-260708-l9w5jhsw	331	20	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	331	21	fever	fever	NN
cord-260708-l9w5jhsw	331	22	virus	virus	NN
cord-260708-l9w5jhsw	331	23	genome	genome	NN
cord-260708-l9w5jhsw	331	24	L	L	NNP
cord-260708-l9w5jhsw	331	25	RNA	RNA	NNP
cord-260708-l9w5jhsw	331	26	segment	segment	NN
cord-260708-l9w5jhsw	331	27	and	and	CC
cord-260708-l9w5jhsw	331	28	encoded	encode	VBD
cord-260708-l9w5jhsw	331	29	protein	protein	NN
cord-260708-l9w5jhsw	331	30	)	)	-RRB-
cord-260708-l9w5jhsw	332	1	5'-Triphosphate	5'-triphosphate	JJ
cord-260708-l9w5jhsw	333	1	RNA	RNA	NNP
cord-260708-l9w5jhsw	333	2	is	be	VBZ
cord-260708-l9w5jhsw	333	3	the	the	DT
cord-260708-l9w5jhsw	333	4	ligand	ligand	NN
cord-260708-l9w5jhsw	333	5	for	for	IN
cord-260708-l9w5jhsw	333	6	RIG	rig	NN
cord-260708-l9w5jhsw	333	7	-	-	:
cord-260708-l9w5jhsw	333	8	I	i	NN
cord-260708-l9w5jhsw	334	1	The	the	DT
cord-260708-l9w5jhsw	334	2	role	role	NN
cord-260708-l9w5jhsw	334	3	of	of	IN
cord-260708-l9w5jhsw	334	4	motor	motor	NN
cord-260708-l9w5jhsw	334	5	proteins	protein	NNS
cord-260708-l9w5jhsw	334	6	in	in	IN
cord-260708-l9w5jhsw	334	7	endosomal	endosomal	NNP
cord-260708-l9w5jhsw	334	8	sorting	sort	VBG
cord-260708-l9w5jhsw	334	9	Cholesterol	cholesterol	NN
cord-260708-l9w5jhsw	334	10	is	be	VBZ
cord-260708-l9w5jhsw	334	11	required	require	VBN
cord-260708-l9w5jhsw	334	12	for	for	IN
cord-260708-l9w5jhsw	334	13	endocytosis	endocytosis	NN
cord-260708-l9w5jhsw	334	14	and	and	CC
cord-260708-l9w5jhsw	334	15	endosomal	endosomal	NN
cord-260708-l9w5jhsw	334	16	escape	escape	NN
cord-260708-l9w5jhsw	334	17	of	of	IN
cord-260708-l9w5jhsw	334	18	adenovirus	adenovirus	NN
cord-260708-l9w5jhsw	334	19	type	type	NN
cord-260708-l9w5jhsw	334	20	2	2	CD
cord-260708-l9w5jhsw	334	21	Structural	structural	JJ
cord-260708-l9w5jhsw	334	22	basis	basis	NN
cord-260708-l9w5jhsw	334	23	for	for	IN
cord-260708-l9w5jhsw	334	24	the	the	DT
cord-260708-l9w5jhsw	334	25	removal	removal	NN
cord-260708-l9w5jhsw	334	26	of	of	IN
cord-260708-l9w5jhsw	334	27	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	334	28	and	and	CC
cord-260708-l9w5jhsw	334	29	interferon	interferon	NN
cord-260708-l9w5jhsw	334	30	-	-	HYPH
cord-260708-l9w5jhsw	334	31	stimulated	stimulate	VBN
cord-260708-l9w5jhsw	334	32	gene	gene	NN
cord-260708-l9w5jhsw	334	33	15	15	CD
cord-260708-l9w5jhsw	334	34	by	by	IN
cord-260708-l9w5jhsw	334	35	a	a	DT
cord-260708-l9w5jhsw	334	36	viral	viral	JJ
cord-260708-l9w5jhsw	334	37	ovarian	ovarian	JJ
cord-260708-l9w5jhsw	334	38	tumor	tumor	NN
cord-260708-l9w5jhsw	334	39	domain	domain	NN
cord-260708-l9w5jhsw	334	40	-	-	HYPH
cord-260708-l9w5jhsw	334	41	containing	contain	VBG
cord-260708-l9w5jhsw	334	42	protease	protease	NN
cord-260708-l9w5jhsw	334	43	Non	non	JJ
cord-260708-l9w5jhsw	334	44	-	-	JJ
cord-260708-l9w5jhsw	334	45	viral	viral	JJ
cord-260708-l9w5jhsw	334	46	sequences	sequence	NNS
cord-260708-l9w5jhsw	334	47	at	at	IN
cord-260708-l9w5jhsw	334	48	the	the	DT
cord-260708-l9w5jhsw	334	49	5	5	CD
cord-260708-l9w5jhsw	334	50	'	'	POS
cord-260708-l9w5jhsw	334	51	ends	end	NNS
cord-260708-l9w5jhsw	334	52	of	of	IN
cord-260708-l9w5jhsw	334	53	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	334	54	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	334	55	S	S	NNP
cord-260708-l9w5jhsw	335	1	mRNAs	mRNAs	.
cord-260708-l9w5jhsw	336	1	Induction	induction	NN
cord-260708-l9w5jhsw	336	2	of	of	IN
cord-260708-l9w5jhsw	336	3	caspase	caspase	NN
cord-260708-l9w5jhsw	336	4	activation	activation	NN
cord-260708-l9w5jhsw	336	5	and	and	CC
cord-260708-l9w5jhsw	336	6	cleavage	cleavage	NN
cord-260708-l9w5jhsw	336	7	of	of	IN
cord-260708-l9w5jhsw	336	8	the	the	DT
cord-260708-l9w5jhsw	336	9	viral	viral	JJ
cord-260708-l9w5jhsw	336	10	nucleocapsid	nucleocapsid	NNP
cord-260708-l9w5jhsw	336	11	protein	protein	NN
cord-260708-l9w5jhsw	336	12	in	in	IN
cord-260708-l9w5jhsw	336	13	different	different	JJ
cord-260708-l9w5jhsw	336	14	cell	cell	NN
cord-260708-l9w5jhsw	336	15	types	type	NNS
cord-260708-l9w5jhsw	336	16	during	during	IN
cord-260708-l9w5jhsw	336	17	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	336	18	-	-	HYPH
cord-260708-l9w5jhsw	336	19	Congo	Congo	NNP
cord-260708-l9w5jhsw	336	20	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	336	21	fever	fever	NN
cord-260708-l9w5jhsw	336	22	virus	virus	NN
cord-260708-l9w5jhsw	336	23	infection	infection	NN
cord-260708-l9w5jhsw	336	24	Differential	differential	JJ
cord-260708-l9w5jhsw	336	25	roles	role	NNS
cord-260708-l9w5jhsw	336	26	of	of	IN
cord-260708-l9w5jhsw	336	27	MDA5	MDA5	NNP
cord-260708-l9w5jhsw	336	28	and	and	CC
cord-260708-l9w5jhsw	336	29	RIG	rig	NN
cord-260708-l9w5jhsw	337	1	-I	-i	DT
cord-260708-l9w5jhsw	337	2	helicases	helicase	NNS
cord-260708-l9w5jhsw	337	3	in	in	IN
cord-260708-l9w5jhsw	337	4	the	the	DT
cord-260708-l9w5jhsw	337	5	recognition	recognition	NN
cord-260708-l9w5jhsw	337	6	of	of	IN
cord-260708-l9w5jhsw	337	7	RNA	RNA	NNP
cord-260708-l9w5jhsw	337	8	viruses	virus	NNS
cord-260708-l9w5jhsw	337	9	DUBA	DUBA	NNP
cord-260708-l9w5jhsw	337	10	:	:	:
cord-260708-l9w5jhsw	337	11	a	a	DT
cord-260708-l9w5jhsw	337	12	deubiquitinase	deubiquitinase	NN
cord-260708-l9w5jhsw	337	13	that	that	WDT
cord-260708-l9w5jhsw	337	14	regulates	regulate	VBZ
cord-260708-l9w5jhsw	337	15	type	type	NN
cord-260708-l9w5jhsw	338	1	I	-PRON-	PRP
cord-260708-l9w5jhsw	338	2	interferon	interferon	VBD
cord-260708-l9w5jhsw	338	3	production	production	NN
cord-260708-l9w5jhsw	338	4	Sequence	sequence	NN
cord-260708-l9w5jhsw	338	5	determination	determination	NN
cord-260708-l9w5jhsw	338	6	of	of	IN
cord-260708-l9w5jhsw	338	7	the	the	DT
cord-260708-l9w5jhsw	338	8	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	338	9	-	-	HYPH
cord-260708-l9w5jhsw	338	10	Congo	Congo	NNP
cord-260708-l9w5jhsw	338	11	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	338	12	fever	fever	NN
cord-260708-l9w5jhsw	338	13	virus	virus	NN
cord-260708-l9w5jhsw	338	14	L	l	NN
cord-260708-l9w5jhsw	338	15	segment	segment	NN
cord-260708-l9w5jhsw	338	16	Role	role	NN
cord-260708-l9w5jhsw	338	17	of	of	IN
cord-260708-l9w5jhsw	338	18	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	338	19	-	-	:
cord-260708-l9w5jhsw	338	20	and	and	CC
cord-260708-l9w5jhsw	338	21	Ubl	Ubl	NNP
cord-260708-l9w5jhsw	338	22	-	-	HYPH
cord-260708-l9w5jhsw	338	23	binding	bind	VBG
cord-260708-l9w5jhsw	338	24	proteins	protein	NNS
cord-260708-l9w5jhsw	338	25	in	in	IN
cord-260708-l9w5jhsw	338	26	cell	cell	NN
cord-260708-l9w5jhsw	338	27	signaling	signal	VBG
cord-260708-l9w5jhsw	338	28	Breaking	break	VBG
cord-260708-l9w5jhsw	338	29	the	the	DT
cord-260708-l9w5jhsw	338	30	chains	chain	NNS
cord-260708-l9w5jhsw	338	31	:	:	:
cord-260708-l9w5jhsw	339	1	structure	structure	NN
cord-260708-l9w5jhsw	339	2	and	and	CC
cord-260708-l9w5jhsw	339	3	function	function	NN
cord-260708-l9w5jhsw	339	4	of	of	IN
cord-260708-l9w5jhsw	339	5	the	the	DT
cord-260708-l9w5jhsw	339	6	deubiquitinases	deubiquitinases	NNP
cord-260708-l9w5jhsw	339	7	Three	Three	NNP
cord-260708-l9w5jhsw	339	8	-	-	HYPH
cord-260708-l9w5jhsw	339	9	dimensional	dimensional	JJ
cord-260708-l9w5jhsw	339	10	structure	structure	NN
cord-260708-l9w5jhsw	339	11	of	of	IN
cord-260708-l9w5jhsw	339	12	the	the	DT
cord-260708-l9w5jhsw	339	13	adenine	adenine	NN
cord-260708-l9w5jhsw	339	14	-	-	HYPH
cord-260708-l9w5jhsw	339	15	specific	specific	JJ
cord-260708-l9w5jhsw	339	16	DNA	dna	NN
cord-260708-l9w5jhsw	339	17	methyltransferase	methyltransferase	NN
cord-260708-l9w5jhsw	339	18	M.Taq	M.Taq	NNP
cord-260708-l9w5jhsw	339	19	I	-PRON-	PRP
cord-260708-l9w5jhsw	339	20	in	in	IN
cord-260708-l9w5jhsw	339	21	complex	complex	NN
cord-260708-l9w5jhsw	339	22	with	with	IN
cord-260708-l9w5jhsw	339	23	the	the	DT
cord-260708-l9w5jhsw	339	24	cofactor	cofactor	NN
cord-260708-l9w5jhsw	339	25	S	S	NNP
cord-260708-l9w5jhsw	339	26	-	-	HYPH
cord-260708-l9w5jhsw	339	27	adenosylmethionine	adenosylmethionine	NNP
cord-260708-l9w5jhsw	339	28	Autocatalytic	autocatalytic	JJ
cord-260708-l9w5jhsw	339	29	processing	processing	NN
cord-260708-l9w5jhsw	339	30	of	of	IN
cord-260708-l9w5jhsw	339	31	the	the	DT
cord-260708-l9w5jhsw	339	32	223-kDa	223-kda	JJ
cord-260708-l9w5jhsw	339	33	protein	protein	NN
cord-260708-l9w5jhsw	339	34	of	of	IN
cord-260708-l9w5jhsw	339	35	blueberry	blueberry	NN
cord-260708-l9w5jhsw	339	36	scorch	scorch	VBP
cord-260708-l9w5jhsw	339	37	carlavirus	carlavirus	NNP
cord-260708-l9w5jhsw	339	38	by	by	IN
cord-260708-l9w5jhsw	339	39	a	a	DT
cord-260708-l9w5jhsw	339	40	papain	papain	NN
cord-260708-l9w5jhsw	339	41	-	-	HYPH
cord-260708-l9w5jhsw	339	42	like	like	JJ
cord-260708-l9w5jhsw	339	43	proteinase	proteinase	NN
cord-260708-l9w5jhsw	339	44	Regulation	regulation	NN
cord-260708-l9w5jhsw	339	45	of	of	IN
cord-260708-l9w5jhsw	339	46	virus	virus	NN
cord-260708-l9w5jhsw	339	47	-	-	HYPH
cord-260708-l9w5jhsw	339	48	triggered	trigger	VBN
cord-260708-l9w5jhsw	339	49	signaling	signaling	NN
cord-260708-l9w5jhsw	339	50	by	by	IN
cord-260708-l9w5jhsw	339	51	OTUB1-and	OTUB1-and	NNP
cord-260708-l9w5jhsw	339	52	OTUB2-mediated	OTUB2-mediated	NNP
cord-260708-l9w5jhsw	339	53	deubiquitination	deubiquitination	NN
cord-260708-l9w5jhsw	339	54	of	of	IN
cord-260708-l9w5jhsw	339	55	TRAF3	TRAF3	NNP
cord-260708-l9w5jhsw	340	1	and	and	CC
cord-260708-l9w5jhsw	340	2	TRAF6	TRAF6	NNP
cord-260708-l9w5jhsw	341	1	The	the	DT
cord-260708-l9w5jhsw	341	2	L	L	NNP
cord-260708-l9w5jhsw	341	3	protein	protein	NN
cord-260708-l9w5jhsw	341	4	of	of	IN
cord-260708-l9w5jhsw	341	5	Rift	Rift	NNP
cord-260708-l9w5jhsw	341	6	Valley	Valley	NNP
cord-260708-l9w5jhsw	341	7	fever	fever	NN
cord-260708-l9w5jhsw	341	8	virus	virus	NN
cord-260708-l9w5jhsw	341	9	can	can	MD
cord-260708-l9w5jhsw	341	10	rescue	rescue	VB
cord-260708-l9w5jhsw	341	11	viral	viral	JJ
cord-260708-l9w5jhsw	341	12	ribonucleoproteins	ribonucleoprotein	NNS
cord-260708-l9w5jhsw	341	13	and	and	CC
cord-260708-l9w5jhsw	341	14	transcribe	transcribe	VB
cord-260708-l9w5jhsw	341	15	synthetic	synthetic	JJ
cord-260708-l9w5jhsw	341	16	genome	genome	NN
cord-260708-l9w5jhsw	341	17	-	-	HYPH
cord-260708-l9w5jhsw	341	18	like	like	JJ
cord-260708-l9w5jhsw	341	19	RNA	RNA	NNP
cord-260708-l9w5jhsw	341	20	molecules	molecule	NNS
cord-260708-l9w5jhsw	341	21	Morphogenesis	Morphogenesis	NNP
cord-260708-l9w5jhsw	341	22	of	of	IN
cord-260708-l9w5jhsw	341	23	post	post	JJ
cord-260708-l9w5jhsw	341	24	-	-	JJ
cord-260708-l9w5jhsw	341	25	Golgi	golgi	JJ
cord-260708-l9w5jhsw	341	26	transport	transport	NN
cord-260708-l9w5jhsw	341	27	carriers	carrier	NNS
cord-260708-l9w5jhsw	342	1	Ticks	tick	NNS
cord-260708-l9w5jhsw	342	2	associated	associate	VBN
cord-260708-l9w5jhsw	342	3	with	with	IN
cord-260708-l9w5jhsw	342	4	macquarie	macquarie	NNP
cord-260708-l9w5jhsw	342	5	island	island	NNP
cord-260708-l9w5jhsw	342	6	penguins	penguin	NNS
cord-260708-l9w5jhsw	342	7	carry	carry	VBP
cord-260708-l9w5jhsw	342	8	arboviruses	arbovirus	NNS
cord-260708-l9w5jhsw	342	9	from	from	IN
cord-260708-l9w5jhsw	342	10	four	four	CD
cord-260708-l9w5jhsw	342	11	genera	genus	NNS
cord-260708-l9w5jhsw	342	12	A	a	DT
cord-260708-l9w5jhsw	342	13	novel	novel	JJ
cord-260708-l9w5jhsw	342	14	superfamily	superfamily	NN
cord-260708-l9w5jhsw	342	15	of	of	IN
cord-260708-l9w5jhsw	342	16	predicted	predict	VBN
cord-260708-l9w5jhsw	342	17	cysteine	cysteine	NN
cord-260708-l9w5jhsw	342	18	proteases	protease	NNS
cord-260708-l9w5jhsw	342	19	from	from	IN
cord-260708-l9w5jhsw	342	20	eukaryotes	eukaryote	NNS
cord-260708-l9w5jhsw	342	21	,	,	,
cord-260708-l9w5jhsw	342	22	viruses	virus	NNS
cord-260708-l9w5jhsw	342	23	and	and	CC
cord-260708-l9w5jhsw	342	24	Chlamydia	Chlamydia	NNP
cord-260708-l9w5jhsw	342	25	pneumoniae	pneumoniae	NN
cord-260708-l9w5jhsw	342	26	High	high	JJ
cord-260708-l9w5jhsw	342	27	-	-	HYPH
cord-260708-l9w5jhsw	342	28	throughput	throughput	NN
cord-260708-l9w5jhsw	342	29	immunoblotting	immunoblotting	NN
cord-260708-l9w5jhsw	342	30	.	.	.
cord-260708-l9w5jhsw	343	1	Ubiquitiinlike	ubiquitiinlike	JJ
cord-260708-l9w5jhsw	343	2	protein	protein	NN
cord-260708-l9w5jhsw	344	1	ISG15	ISG15	NNP
cord-260708-l9w5jhsw	344	2	modifies	modify	VBZ
cord-260708-l9w5jhsw	344	3	key	key	JJ
cord-260708-l9w5jhsw	344	4	regulators	regulator	NNS
cord-260708-l9w5jhsw	344	5	of	of	IN
cord-260708-l9w5jhsw	344	6	signal	signal	NN
cord-260708-l9w5jhsw	344	7	transduction	transduction	NN
cord-260708-l9w5jhsw	344	8	Viral	viral	JJ
cord-260708-l9w5jhsw	344	9	activation	activation	NN
cord-260708-l9w5jhsw	344	10	of	of	IN
cord-260708-l9w5jhsw	344	11	macrophages	macrophage	NNS
cord-260708-l9w5jhsw	344	12	through	through	IN
cord-260708-l9w5jhsw	344	13	TLRdependent	tlrdependent	NN
cord-260708-l9w5jhsw	344	14	and	and	CC
cord-260708-l9w5jhsw	344	15	-independent	-independent	JJ
cord-260708-l9w5jhsw	344	16	pathways	pathway	NNS
cord-260708-l9w5jhsw	344	17	Nairobi	Nairobi	NNP
cord-260708-l9w5jhsw	344	18	sheep	sheep	NN
cord-260708-l9w5jhsw	344	19	disease	disease	NN
cord-260708-l9w5jhsw	344	20	virus	virus	NN
cord-260708-l9w5jhsw	344	21	,	,	,
cord-260708-l9w5jhsw	344	22	an	an	DT
cord-260708-l9w5jhsw	344	23	important	important	JJ
cord-260708-l9w5jhsw	344	24	tick	tick	NN
cord-260708-l9w5jhsw	344	25	-	-	HYPH
cord-260708-l9w5jhsw	344	26	borne	bear	VBN
cord-260708-l9w5jhsw	344	27	pathogen	pathogen	NN
cord-260708-l9w5jhsw	344	28	of	of	IN
cord-260708-l9w5jhsw	344	29	sheep	sheep	NNS
cord-260708-l9w5jhsw	344	30	and	and	CC
cord-260708-l9w5jhsw	344	31	goats	goat	NNS
cord-260708-l9w5jhsw	344	32	in	in	IN
cord-260708-l9w5jhsw	344	33	Africa	Africa	NNP
cord-260708-l9w5jhsw	344	34	,	,	,
cord-260708-l9w5jhsw	344	35	is	be	VBZ
cord-260708-l9w5jhsw	344	36	also	also	RB
cord-260708-l9w5jhsw	344	37	present	present	JJ
cord-260708-l9w5jhsw	344	38	in	in	IN
cord-260708-l9w5jhsw	344	39	Asia	Asia	NNP
cord-260708-l9w5jhsw	344	40	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	344	41	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	344	42	M	M	NNP
cord-260708-l9w5jhsw	344	43	RNA	RNA	NNP
cord-260708-l9w5jhsw	344	44	:	:	:
cord-260708-l9w5jhsw	344	45	nucleotide	nucleotide	JJ
cord-260708-l9w5jhsw	344	46	sequence	sequence	NN
cord-260708-l9w5jhsw	344	47	and	and	CC
cord-260708-l9w5jhsw	344	48	coding	coding	NN
cord-260708-l9w5jhsw	344	49	strategy	strategy	NN
cord-260708-l9w5jhsw	345	1	Large	large	JJ
cord-260708-l9w5jhsw	345	2	RNA	RNA	NNP
cord-260708-l9w5jhsw	345	3	segment	segment	NN
cord-260708-l9w5jhsw	345	4	of	of	IN
cord-260708-l9w5jhsw	345	5	Dugbe	Dugbe	NNP
cord-260708-l9w5jhsw	345	6	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	345	7	encodes	encode	VBZ
cord-260708-l9w5jhsw	345	8	the	the	DT
cord-260708-l9w5jhsw	345	9	putative	putative	JJ
cord-260708-l9w5jhsw	345	10	RNA	RNA	NNP
cord-260708-l9w5jhsw	345	11	polymerase	polymerase	NN
cord-260708-l9w5jhsw	345	12	Molecular	Molecular	NNP
cord-260708-l9w5jhsw	345	13	Biology	Biology	NNP
cord-260708-l9w5jhsw	345	14	of	of	IN
cord-260708-l9w5jhsw	345	15	Nairoviruses	Nairoviruses	NNP
cord-260708-l9w5jhsw	346	1	Hantavirus	Hantavirus	NNP
cord-260708-l9w5jhsw	346	2	N	N	NNP
cord-260708-l9w5jhsw	346	3	protein	protein	NN
cord-260708-l9w5jhsw	346	4	exhibits	exhibit	VBZ
cord-260708-l9w5jhsw	346	5	genus	genus	NN
cord-260708-l9w5jhsw	346	6	-	-	HYPH
cord-260708-l9w5jhsw	346	7	specific	specific	JJ
cord-260708-l9w5jhsw	346	8	recognition	recognition	NN
cord-260708-l9w5jhsw	346	9	of	of	IN
cord-260708-l9w5jhsw	346	10	the	the	DT
cord-260708-l9w5jhsw	346	11	viral	viral	JJ
cord-260708-l9w5jhsw	346	12	RNA	RNA	NNP
cord-260708-l9w5jhsw	346	13	panhandle	panhandle	NN
cord-260708-l9w5jhsw	346	14	Investigating	investigate	VBG
cord-260708-l9w5jhsw	346	15	the	the	DT
cord-260708-l9w5jhsw	346	16	specificity	specificity	NN
cord-260708-l9w5jhsw	346	17	and	and	CC
cord-260708-l9w5jhsw	346	18	stoichiometry	stoichiometry	NN
cord-260708-l9w5jhsw	346	19	of	of	IN
cord-260708-l9w5jhsw	346	20	RNA	RNA	NNP
cord-260708-l9w5jhsw	346	21	binding	bind	VBG
cord-260708-l9w5jhsw	346	22	by	by	IN
cord-260708-l9w5jhsw	346	23	the	the	DT
cord-260708-l9w5jhsw	346	24	nucleocapsid	nucleocapsid	NNP
cord-260708-l9w5jhsw	346	25	protein	protein	NN
cord-260708-l9w5jhsw	346	26	of	of	IN
cord-260708-l9w5jhsw	346	27	Bunyamwera	Bunyamwera	NNP
cord-260708-l9w5jhsw	346	28	virus	virus	NN
cord-260708-l9w5jhsw	346	29	Chaperone	chaperone	NN
cord-260708-l9w5jhsw	346	30	selection	selection	NN
cord-260708-l9w5jhsw	346	31	during	during	IN
cord-260708-l9w5jhsw	346	32	glycoprotein	glycoprotein	NN
cord-260708-l9w5jhsw	346	33	translocation	translocation	NN
cord-260708-l9w5jhsw	346	34	into	into	IN
cord-260708-l9w5jhsw	346	35	the	the	DT
cord-260708-l9w5jhsw	346	36	endoplasmic	endoplasmic	NN
cord-260708-l9w5jhsw	346	37	reticulum	reticulum	NN
cord-260708-l9w5jhsw	346	38	On	on	IN
cord-260708-l9w5jhsw	346	39	a	a	DT
cord-260708-l9w5jhsw	346	40	tick	tick	NN
cord-260708-l9w5jhsw	346	41	-	-	HYPH
cord-260708-l9w5jhsw	346	42	borne	bear	VBN
cord-260708-l9w5jhsw	346	43	gastroenteritis	gastroenteritis	NN
cord-260708-l9w5jhsw	346	44	of	of	IN
cord-260708-l9w5jhsw	346	45	sheep	sheep	NNS
cord-260708-l9w5jhsw	346	46	and	and	CC
cord-260708-l9w5jhsw	346	47	goats	goat	NNS
cord-260708-l9w5jhsw	346	48	occurring	occur	VBG
cord-260708-l9w5jhsw	346	49	in	in	IN
cord-260708-l9w5jhsw	347	1	British	British	NNP
cord-260708-l9w5jhsw	347	2	East	East	NNP
cord-260708-l9w5jhsw	347	3	Africa	Africa	NNP
cord-260708-l9w5jhsw	347	4	Rift	Rift	NNP
cord-260708-l9w5jhsw	347	5	Valley	Valley	NNP
cord-260708-l9w5jhsw	347	6	fever	fever	NN
cord-260708-l9w5jhsw	347	7	virus	virus	NN
cord-260708-l9w5jhsw	347	8	L	l	NN
cord-260708-l9w5jhsw	347	9	segment	segment	NN
cord-260708-l9w5jhsw	347	10	:	:	:
cord-260708-l9w5jhsw	347	11	correction	correction	NN
cord-260708-l9w5jhsw	347	12	of	of	IN
cord-260708-l9w5jhsw	347	13	the	the	DT
cord-260708-l9w5jhsw	347	14	sequence	sequence	NN
cord-260708-l9w5jhsw	347	15	and	and	CC
cord-260708-l9w5jhsw	347	16	possible	possible	JJ
cord-260708-l9w5jhsw	347	17	functional	functional	JJ
cord-260708-l9w5jhsw	347	18	role	role	NN
cord-260708-l9w5jhsw	347	19	of	of	IN
cord-260708-l9w5jhsw	347	20	newly	newly	RB
cord-260708-l9w5jhsw	347	21	identified	identify	VBN
cord-260708-l9w5jhsw	347	22	regions	region	NNS
cord-260708-l9w5jhsw	347	23	conserved	conserve	VBN
cord-260708-l9w5jhsw	347	24	in	in	IN
cord-260708-l9w5jhsw	347	25	RNA	rna	NN
cord-260708-l9w5jhsw	347	26	-	-	HYPH
cord-260708-l9w5jhsw	347	27	dependent	dependent	JJ
cord-260708-l9w5jhsw	347	28	polymerases	polymerase	NNS
cord-260708-l9w5jhsw	348	1	Human	human	JJ
cord-260708-l9w5jhsw	348	2	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	348	3	-	-	HYPH
cord-260708-l9w5jhsw	348	4	Congo	Congo	NNP
cord-260708-l9w5jhsw	348	5	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	348	6	fever	fever	NN
cord-260708-l9w5jhsw	348	7	Furin	furin	NN
cord-260708-l9w5jhsw	348	8	:	:	:
cord-260708-l9w5jhsw	348	9	a	a	DT
cord-260708-l9w5jhsw	348	10	mammalian	mammalian	JJ
cord-260708-l9w5jhsw	348	11	subtilisin	subtilisin	NNS
cord-260708-l9w5jhsw	348	12	/	/	SYM
cord-260708-l9w5jhsw	348	13	Kex2p	Kex2p	NNP
cord-260708-l9w5jhsw	348	14	-	-	HYPH
cord-260708-l9w5jhsw	348	15	like	like	JJ
cord-260708-l9w5jhsw	348	16	endoprotease	endoprotease	NN
cord-260708-l9w5jhsw	348	17	involved	involve	VBN
cord-260708-l9w5jhsw	348	18	in	in	IN
cord-260708-l9w5jhsw	348	19	processing	processing	NN
cord-260708-l9w5jhsw	348	20	of	of	IN
cord-260708-l9w5jhsw	348	21	a	a	DT
cord-260708-l9w5jhsw	348	22	wide	wide	JJ
cord-260708-l9w5jhsw	348	23	variety	variety	NN
cord-260708-l9w5jhsw	348	24	of	of	IN
cord-260708-l9w5jhsw	348	25	precursor	precursor	NN
cord-260708-l9w5jhsw	348	26	proteins	protein	NNS
cord-260708-l9w5jhsw	348	27	Crystal	Crystal	NNP
cord-260708-l9w5jhsw	348	28	structure	structure	NN
cord-260708-l9w5jhsw	348	29	of	of	IN
cord-260708-l9w5jhsw	348	30	the	the	DT
cord-260708-l9w5jhsw	348	31	interferon	interferon	NN
cord-260708-l9w5jhsw	348	32	-	-	HYPH
cord-260708-l9w5jhsw	348	33	induced	induce	VBN
cord-260708-l9w5jhsw	348	34	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	348	35	-	-	HYPH
cord-260708-l9w5jhsw	348	36	like	like	JJ
cord-260708-l9w5jhsw	348	37	protein	protein	NN
cord-260708-l9w5jhsw	349	1	ISG15	ISG15	NNP
cord-260708-l9w5jhsw	350	1	The	the	DT
cord-260708-l9w5jhsw	350	2	anti	anti	JJ
cord-260708-l9w5jhsw	350	3	-	-	JJ
cord-260708-l9w5jhsw	350	4	HIV	hiv	JJ
cord-260708-l9w5jhsw	350	5	pentameric	pentameric	NN
cord-260708-l9w5jhsw	350	6	pseudopeptide	pseudopeptide	NN
cord-260708-l9w5jhsw	350	7	HB-19	HB-19	NNP
cord-260708-l9w5jhsw	350	8	binds	bind	VBZ
cord-260708-l9w5jhsw	350	9	the	the	DT
cord-260708-l9w5jhsw	350	10	C	c	NN
cord-260708-l9w5jhsw	350	11	-	-	HYPH
cord-260708-l9w5jhsw	350	12	terminal	terminal	JJ
cord-260708-l9w5jhsw	350	13	end	end	NN
cord-260708-l9w5jhsw	350	14	of	of	IN
cord-260708-l9w5jhsw	350	15	nucleolin	nucleolin	NN
cord-260708-l9w5jhsw	350	16	and	and	CC
cord-260708-l9w5jhsw	350	17	prevents	prevent	VBZ
cord-260708-l9w5jhsw	350	18	anchorage	anchorage	NN
cord-260708-l9w5jhsw	350	19	of	of	IN
cord-260708-l9w5jhsw	350	20	virus	virus	NN
cord-260708-l9w5jhsw	350	21	particles	particle	NNS
cord-260708-l9w5jhsw	350	22	in	in	IN
cord-260708-l9w5jhsw	350	23	the	the	DT
cord-260708-l9w5jhsw	350	24	plasma	plasma	NN
cord-260708-l9w5jhsw	350	25	membrane	membrane	NN
cord-260708-l9w5jhsw	350	26	of	of	IN
cord-260708-l9w5jhsw	350	27	target	target	NN
cord-260708-l9w5jhsw	350	28	cells	cell	NNS
cord-260708-l9w5jhsw	350	29	N6-methyl	n6-methyl	NN
cord-260708-l9w5jhsw	350	30	-	-	HYPH
cord-260708-l9w5jhsw	350	31	adenosine	adenosine	NN
cord-260708-l9w5jhsw	350	32	(	(	-LRB-
cord-260708-l9w5jhsw	350	33	m6A	m6A	NNP
cord-260708-l9w5jhsw	350	34	)	)	-RRB-
cord-260708-l9w5jhsw	350	35	in	in	IN
cord-260708-l9w5jhsw	350	36	RNA	RNA	NNP
cord-260708-l9w5jhsw	350	37	:	:	:
cord-260708-l9w5jhsw	350	38	an	an	DT
cord-260708-l9w5jhsw	350	39	old	old	JJ
cord-260708-l9w5jhsw	350	40	modification	modification	NN
cord-260708-l9w5jhsw	350	41	with	with	IN
cord-260708-l9w5jhsw	350	42	a	a	DT
cord-260708-l9w5jhsw	350	43	novel	novel	JJ
cord-260708-l9w5jhsw	350	44	epigenetic	epigenetic	JJ
cord-260708-l9w5jhsw	350	45	function	function	NN
cord-260708-l9w5jhsw	350	46	RNA	RNA	NNP
cord-260708-l9w5jhsw	350	47	binding	bind	VBG
cord-260708-l9w5jhsw	350	48	properties	property	NNS
cord-260708-l9w5jhsw	350	49	of	of	IN
cord-260708-l9w5jhsw	350	50	bunyamwera	bunyamwera	NNP
cord-260708-l9w5jhsw	350	51	virus	virus	NN
cord-260708-l9w5jhsw	350	52	nucleocapsid	nucleocapsid	NNP
cord-260708-l9w5jhsw	350	53	protein	protein	NN
cord-260708-l9w5jhsw	350	54	and	and	CC
cord-260708-l9w5jhsw	350	55	selective	selective	JJ
cord-260708-l9w5jhsw	350	56	binding	binding	NN
cord-260708-l9w5jhsw	350	57	to	to	IN
cord-260708-l9w5jhsw	350	58	an	an	DT
cord-260708-l9w5jhsw	350	59	element	element	NN
cord-260708-l9w5jhsw	350	60	in	in	IN
cord-260708-l9w5jhsw	350	61	the	the	DT
cord-260708-l9w5jhsw	350	62	5	5	CD
cord-260708-l9w5jhsw	350	63	'	'	''
cord-260708-l9w5jhsw	350	64	terminus	terminus	NN
cord-260708-l9w5jhsw	350	65	of	of	IN
cord-260708-l9w5jhsw	350	66	the	the	DT
cord-260708-l9w5jhsw	350	67	negative	negative	JJ
cord-260708-l9w5jhsw	350	68	-	-	HYPH
cord-260708-l9w5jhsw	350	69	sense	sense	NN
cord-260708-l9w5jhsw	350	70	S	s	NN
cord-260708-l9w5jhsw	350	71	segment	segment	NN
cord-260708-l9w5jhsw	351	1	Genetic	genetic	JJ
cord-260708-l9w5jhsw	351	2	characterization	characterization	NN
cord-260708-l9w5jhsw	351	3	of	of	IN
cord-260708-l9w5jhsw	351	4	the	the	DT
cord-260708-l9w5jhsw	351	5	M	M	NNP
cord-260708-l9w5jhsw	351	6	RNA	RNA	NNP
cord-260708-l9w5jhsw	351	7	segment	segment	NN
cord-260708-l9w5jhsw	351	8	of	of	IN
cord-260708-l9w5jhsw	351	9	Crimean	crimean	JJ
cord-260708-l9w5jhsw	351	10	Congo	Congo	NNP
cord-260708-l9w5jhsw	351	11	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	351	12	fever	fever	NN
cord-260708-l9w5jhsw	351	13	virus	virus	NN
cord-260708-l9w5jhsw	351	14	strains	strain	VBZ
cord-260708-l9w5jhsw	351	15	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	351	16	-	-	HYPH
cord-260708-l9w5jhsw	351	17	Congo	Congo	NNP
cord-260708-l9w5jhsw	351	18	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	351	19	fever	fever	NN
cord-260708-l9w5jhsw	351	20	in	in	IN
cord-260708-l9w5jhsw	351	21	Bulgaria	Bulgaria	NNP
cord-260708-l9w5jhsw	351	22	Emergence	Emergence	NNP
cord-260708-l9w5jhsw	351	23	of	of	IN
cord-260708-l9w5jhsw	351	24	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	351	25	-	-	HYPH
cord-260708-l9w5jhsw	351	26	Congo	Congo	NNP
cord-260708-l9w5jhsw	351	27	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	351	28	fever	fever	NN
cord-260708-l9w5jhsw	351	29	in	in	IN
cord-260708-l9w5jhsw	351	30	Greece	Greece	NNP
cord-260708-l9w5jhsw	351	31	Ecology	Ecology	NNP
cord-260708-l9w5jhsw	351	32	of	of	IN
cord-260708-l9w5jhsw	351	33	the	the	DT
cord-260708-l9w5jhsw	351	34	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	351	35	-	-	HYPH
cord-260708-l9w5jhsw	351	36	Congo	Congo	NNP
cord-260708-l9w5jhsw	351	37	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	351	38	fever	fever	NN
cord-260708-l9w5jhsw	351	39	endemic	endemic	JJ
cord-260708-l9w5jhsw	351	40	area	area	NN
cord-260708-l9w5jhsw	351	41	in	in	IN
cord-260708-l9w5jhsw	351	42	Albania	Albania	NNP
cord-260708-l9w5jhsw	351	43	TAX1BP1	TAX1BP1	NNP
cord-260708-l9w5jhsw	351	44	and	and	CC
cord-260708-l9w5jhsw	351	45	A20	A20	NNP
cord-260708-l9w5jhsw	351	46	inhibit	inhibit	VBP
cord-260708-l9w5jhsw	351	47	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	351	48	signaling	signal	VBG
cord-260708-l9w5jhsw	351	49	by	by	IN
cord-260708-l9w5jhsw	351	50	targeting	target	VBG
cord-260708-l9w5jhsw	351	51	TBK1-IKKi	TBK1-IKKi	NNP
cord-260708-l9w5jhsw	351	52	kinases	kinase	NNS
cord-260708-l9w5jhsw	351	53	Ubiquitin	Ubiquitin	NNP
cord-260708-l9w5jhsw	351	54	-	-	HYPH
cord-260708-l9w5jhsw	351	55	regulated	regulate	VBN
cord-260708-l9w5jhsw	351	56	recruitment	recruitment	NN
cord-260708-l9w5jhsw	351	57	of	of	IN
cord-260708-l9w5jhsw	351	58	IkappaB	IkappaB	NNP
cord-260708-l9w5jhsw	351	59	kinase	kinase	VBZ
cord-260708-l9w5jhsw	351	60	epsilon	epsilon	NN
cord-260708-l9w5jhsw	351	61	to	to	IN
cord-260708-l9w5jhsw	351	62	the	the	DT
cord-260708-l9w5jhsw	351	63	MAVS	MAVS	NNPS
cord-260708-l9w5jhsw	352	1	interferon	interferon	NN
cord-260708-l9w5jhsw	352	2	signaling	signal	VBG
cord-260708-l9w5jhsw	352	3	adapter	adapter	NN
cord-260708-l9w5jhsw	352	4	Ribonucleoproteins	Ribonucleoproteins	NNP
cord-260708-l9w5jhsw	352	5	of	of	IN
cord-260708-l9w5jhsw	352	6	Uukuniemi	Uukuniemi	NNP
cord-260708-l9w5jhsw	352	7	virus	virus	NN
cord-260708-l9w5jhsw	352	8	are	be	VBP
cord-260708-l9w5jhsw	352	9	circular	circular	JJ
cord-260708-l9w5jhsw	352	10	RIG	rig	NN
cord-260708-l9w5jhsw	352	11	-	-	HYPH
cord-260708-l9w5jhsw	352	12	I	i	NN
cord-260708-l9w5jhsw	352	13	-	-	HYPH
cord-260708-l9w5jhsw	352	14	mediated	mediate	VBN
cord-260708-l9w5jhsw	352	15	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	352	16	responses	response	NNS
cord-260708-l9w5jhsw	352	17	to	to	IN
cord-260708-l9w5jhsw	352	18	single	single	RB
cord-260708-l9w5jhsw	352	19	-	-	HYPH
cord-260708-l9w5jhsw	352	20	stranded	strand	VBN
cord-260708-l9w5jhsw	352	21	RNA	RNA	NNP
cord-260708-l9w5jhsw	352	22	bearing	bear	VBG
cord-260708-l9w5jhsw	352	23	5'-phosphates	5'-phosphates	NNP
cord-260708-l9w5jhsw	352	24	Identification	Identification	NNP
cord-260708-l9w5jhsw	352	25	of	of	IN
cord-260708-l9w5jhsw	352	26	four	four	CD
cord-260708-l9w5jhsw	352	27	conserved	conserved	JJ
cord-260708-l9w5jhsw	352	28	motifs	motif	NNS
cord-260708-l9w5jhsw	352	29	among	among	IN
cord-260708-l9w5jhsw	352	30	the	the	DT
cord-260708-l9w5jhsw	352	31	RNA	rna	NN
cord-260708-l9w5jhsw	352	32	-	-	HYPH
cord-260708-l9w5jhsw	352	33	dependent	dependent	JJ
cord-260708-l9w5jhsw	352	34	polymerase	polymerase	NN
cord-260708-l9w5jhsw	352	35	encoding	encoding	NN
cord-260708-l9w5jhsw	352	36	elements	element	NNS
cord-260708-l9w5jhsw	352	37	Cap	Cap	NNP
cord-260708-l9w5jhsw	352	38	binding	bind	VBG
cord-260708-l9w5jhsw	352	39	and	and	CC
cord-260708-l9w5jhsw	352	40	immune	immune	JJ
cord-260708-l9w5jhsw	352	41	evasion	evasion	NN
cord-260708-l9w5jhsw	352	42	revealed	reveal	VBN
cord-260708-l9w5jhsw	352	43	by	by	IN
cord-260708-l9w5jhsw	352	44	Lassa	Lassa	NNP
cord-260708-l9w5jhsw	352	45	nucleoprotein	nucleoprotein	NNP
cord-260708-l9w5jhsw	352	46	structure	structure	NN
cord-260708-l9w5jhsw	352	47	Sequence	sequence	NN
cord-260708-l9w5jhsw	352	48	and	and	CC
cord-260708-l9w5jhsw	352	49	phylogenetic	phylogenetic	JJ
cord-260708-l9w5jhsw	352	50	analysis	analysis	NN
cord-260708-l9w5jhsw	352	51	of	of	IN
cord-260708-l9w5jhsw	352	52	the	the	DT
cord-260708-l9w5jhsw	352	53	large	large	JJ
cord-260708-l9w5jhsw	352	54	(	(	-LRB-
cord-260708-l9w5jhsw	352	55	L	l	NN
cord-260708-l9w5jhsw	352	56	)	)	-RRB-
cord-260708-l9w5jhsw	352	57	segment	segment	NN
cord-260708-l9w5jhsw	352	58	of	of	IN
cord-260708-l9w5jhsw	352	59	the	the	DT
cord-260708-l9w5jhsw	352	60	Tahyna	Tahyna	NNP
cord-260708-l9w5jhsw	352	61	virus	virus	NN
cord-260708-l9w5jhsw	352	62	genome	genome	NN
cord-260708-l9w5jhsw	352	63	Interferons	interferon	NNS
cord-260708-l9w5jhsw	352	64	and	and	CC
cord-260708-l9w5jhsw	352	65	viruses	virus	NNS
cord-260708-l9w5jhsw	352	66	:	:	:
cord-260708-l9w5jhsw	353	1	an	an	DT
cord-260708-l9w5jhsw	353	2	interplay	interplay	NN
cord-260708-l9w5jhsw	353	3	between	between	IN
cord-260708-l9w5jhsw	353	4	induction	induction	NN
cord-260708-l9w5jhsw	353	5	,	,	,
cord-260708-l9w5jhsw	353	6	signalling	signal	VBG
cord-260708-l9w5jhsw	353	7	,	,	,
cord-260708-l9w5jhsw	353	8	antiviral	antiviral	JJ
cord-260708-l9w5jhsw	353	9	responses	response	NNS
cord-260708-l9w5jhsw	353	10	and	and	CC
cord-260708-l9w5jhsw	353	11	virus	virus	NN
cord-260708-l9w5jhsw	353	12	countermeasures	countermeasure	NNS
cord-260708-l9w5jhsw	353	13	Laboratory	laboratory	NN
cord-260708-l9w5jhsw	353	14	infections	infection	NNS
cord-260708-l9w5jhsw	353	15	with	with	IN
cord-260708-l9w5jhsw	353	16	Ganjam	Ganjam	NNP
cord-260708-l9w5jhsw	353	17	virus	virus	NN
cord-260708-l9w5jhsw	353	18	Hantavirus	Hantavirus	NNP
cord-260708-l9w5jhsw	353	19	nucleocapsid	nucleocapsid	NN
cord-260708-l9w5jhsw	353	20	protein	protein	NN
cord-260708-l9w5jhsw	353	21	is	be	VBZ
cord-260708-l9w5jhsw	353	22	expressed	express	VBN
cord-260708-l9w5jhsw	353	23	as	as	IN
cord-260708-l9w5jhsw	353	24	a	a	DT
cord-260708-l9w5jhsw	353	25	membrane	membrane	NN
cord-260708-l9w5jhsw	353	26	-	-	HYPH
cord-260708-l9w5jhsw	353	27	associated	associate	VBN
cord-260708-l9w5jhsw	353	28	protein	protein	NN
cord-260708-l9w5jhsw	353	29	in	in	IN
cord-260708-l9w5jhsw	353	30	the	the	DT
cord-260708-l9w5jhsw	353	31	perinuclear	perinuclear	NNP
cord-260708-l9w5jhsw	353	32	region	region	NN
cord-260708-l9w5jhsw	353	33	Molecular	molecular	JJ
cord-260708-l9w5jhsw	353	34	biology	biology	NN
cord-260708-l9w5jhsw	353	35	of	of	IN
cord-260708-l9w5jhsw	353	36	nairoviruses	nairoviruse	NNS
cord-260708-l9w5jhsw	353	37	1263	1263	CD
cord-260708-l9w5jhsw	353	38	Structure	Structure	NNP
cord-260708-l9w5jhsw	353	39	of	of	IN
cord-260708-l9w5jhsw	353	40	the	the	DT
cord-260708-l9w5jhsw	353	41	Rift	Rift	NNP
cord-260708-l9w5jhsw	353	42	Valley	Valley	NNP
cord-260708-l9w5jhsw	353	43	fever	fever	NN
cord-260708-l9w5jhsw	353	44	virus	virus	NN
cord-260708-l9w5jhsw	353	45	nucleocapsid	nucleocapsid	NN
cord-260708-l9w5jhsw	353	46	protein	protein	NN
cord-260708-l9w5jhsw	353	47	reveals	reveal	VBZ
cord-260708-l9w5jhsw	353	48	another	another	DT
cord-260708-l9w5jhsw	353	49	architecture	architecture	NN
cord-260708-l9w5jhsw	353	50	for	for	IN
cord-260708-l9w5jhsw	353	51	RNA	RNA	NNP
cord-260708-l9w5jhsw	353	52	encapsidation	encapsidation	NN
cord-260708-l9w5jhsw	353	53	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	353	54	RNA	RNA	NNP
cord-260708-l9w5jhsw	353	55	polymerases	polymerase	NNS
cord-260708-l9w5jhsw	353	56	(	(	-LRB-
cord-260708-l9w5jhsw	353	57	L	l	NN
cord-260708-l9w5jhsw	353	58	-	-	HYPH
cord-260708-l9w5jhsw	353	59	protein	protein	NN
cord-260708-l9w5jhsw	353	60	)	)	-RRB-
cord-260708-l9w5jhsw	353	61	have	have	VBP
cord-260708-l9w5jhsw	353	62	an	an	DT
cord-260708-l9w5jhsw	353	63	N	n	CD
cord-260708-l9w5jhsw	353	64	-	-	HYPH
cord-260708-l9w5jhsw	353	65	terminal	terminal	NN
cord-260708-l9w5jhsw	353	66	,	,	,
cord-260708-l9w5jhsw	353	67	influenza	influenza	NN
cord-260708-l9w5jhsw	353	68	-	-	HYPH
cord-260708-l9w5jhsw	353	69	like	like	JJ
cord-260708-l9w5jhsw	353	70	endonuclease	endonuclease	NN
cord-260708-l9w5jhsw	353	71	domain	domain	NN
cord-260708-l9w5jhsw	353	72	,	,	,
cord-260708-l9w5jhsw	353	73	essential	essential	JJ
cord-260708-l9w5jhsw	353	74	for	for	IN
cord-260708-l9w5jhsw	353	75	viral	viral	JJ
cord-260708-l9w5jhsw	353	76	cap	cap	NN
cord-260708-l9w5jhsw	353	77	-	-	HYPH
cord-260708-l9w5jhsw	353	78	dependent	dependent	JJ
cord-260708-l9w5jhsw	353	79	transcription	transcription	NN
cord-260708-l9w5jhsw	353	80	Characterization	characterization	NN
cord-260708-l9w5jhsw	353	81	of	of	IN
cord-260708-l9w5jhsw	353	82	the	the	DT
cord-260708-l9w5jhsw	353	83	nucleic	nucleic	JJ
cord-260708-l9w5jhsw	353	84	acid	acid	NN
cord-260708-l9w5jhsw	353	85	binding	bind	VBG
cord-260708-l9w5jhsw	353	86	properties	property	NNS
cord-260708-l9w5jhsw	353	87	of	of	IN
cord-260708-l9w5jhsw	353	88	tomato	tomato	NN
cord-260708-l9w5jhsw	354	1	spotted	spot	VBN
cord-260708-l9w5jhsw	354	2	wilt	wilt	NNP
cord-260708-l9w5jhsw	354	3	virus	virus	NN
cord-260708-l9w5jhsw	354	4	nucleocapsid	nucleocapsid	NN
cord-260708-l9w5jhsw	354	5	protein	protein	NN
cord-260708-l9w5jhsw	355	1	ISG15	isg15	NN
cord-260708-l9w5jhsw	355	2	:	:	:
cord-260708-l9w5jhsw	356	1	the	the	DT
cord-260708-l9w5jhsw	356	2	immunological	immunological	JJ
cord-260708-l9w5jhsw	356	3	kin	kin	NN
cord-260708-l9w5jhsw	356	4	of	of	IN
cord-260708-l9w5jhsw	356	5	ubiquitin	ubiquitin	NNP
cord-260708-l9w5jhsw	356	6	Completion	Completion	NNP
cord-260708-l9w5jhsw	356	7	of	of	IN
cord-260708-l9w5jhsw	356	8	the	the	DT
cord-260708-l9w5jhsw	356	9	La	La	NNP
cord-260708-l9w5jhsw	356	10	Crosse	Crosse	NNP
cord-260708-l9w5jhsw	356	11	virus	virus	NN
cord-260708-l9w5jhsw	356	12	genome	genome	NN
cord-260708-l9w5jhsw	356	13	sequence	sequence	NN
cord-260708-l9w5jhsw	356	14	and	and	CC
cord-260708-l9w5jhsw	356	15	genetic	genetic	JJ
cord-260708-l9w5jhsw	356	16	comparisons	comparison	NNS
cord-260708-l9w5jhsw	356	17	of	of	IN
cord-260708-l9w5jhsw	356	18	the	the	DT
cord-260708-l9w5jhsw	356	19	L	l	NN
cord-260708-l9w5jhsw	356	20	proteins	protein	NNS
cord-260708-l9w5jhsw	356	21	of	of	IN
cord-260708-l9w5jhsw	356	22	the	the	DT
cord-260708-l9w5jhsw	356	23	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	356	24	Extraction	Extraction	NNP
cord-260708-l9w5jhsw	356	25	of	of	IN
cord-260708-l9w5jhsw	356	26	cholesterol	cholesterol	NN
cord-260708-l9w5jhsw	356	27	with	with	IN
cord-260708-l9w5jhsw	356	28	methyl	methyl	NN
cord-260708-l9w5jhsw	356	29	-	-	HYPH
cord-260708-l9w5jhsw	356	30	betacyclodextrin	betacyclodextrin	NN
cord-260708-l9w5jhsw	356	31	perturbs	perturb	VBZ
cord-260708-l9w5jhsw	356	32	formation	formation	NN
cord-260708-l9w5jhsw	356	33	of	of	IN
cord-260708-l9w5jhsw	356	34	clathrin	clathrin	NN
cord-260708-l9w5jhsw	356	35	-	-	HYPH
cord-260708-l9w5jhsw	356	36	coated	coat	VBN
cord-260708-l9w5jhsw	356	37	endocytic	endocytic	JJ
cord-260708-l9w5jhsw	356	38	vesicles	vesicle	NNS
cord-260708-l9w5jhsw	356	39	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	356	40	-	-	HYPH
cord-260708-l9w5jhsw	356	41	Congo	Congo	NNP
cord-260708-l9w5jhsw	356	42	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	356	43	fever	fever	NN
cord-260708-l9w5jhsw	356	44	virus	virus	NN
cord-260708-l9w5jhsw	356	45	-	-	HYPH
cord-260708-l9w5jhsw	356	46	infected	infect	VBN
cord-260708-l9w5jhsw	356	47	hepatocytes	hepatocyte	NNS
cord-260708-l9w5jhsw	356	48	induce	induce	VBP
cord-260708-l9w5jhsw	356	49	ER	er	NN
cord-260708-l9w5jhsw	356	50	-	-	HYPH
cord-260708-l9w5jhsw	356	51	stress	stress	NN
cord-260708-l9w5jhsw	356	52	and	and	CC
cord-260708-l9w5jhsw	356	53	apoptosis	apoptosis	NN
cord-260708-l9w5jhsw	357	1	crosstalk	crosstalk	NNP
cord-260708-l9w5jhsw	357	2	Ultrastructural	Ultrastructural	NNP
cord-260708-l9w5jhsw	357	3	studies	study	NNS
cord-260708-l9w5jhsw	357	4	on	on	IN
cord-260708-l9w5jhsw	357	5	the	the	DT
cord-260708-l9w5jhsw	357	6	replication	replication	NN
cord-260708-l9w5jhsw	357	7	and	and	CC
cord-260708-l9w5jhsw	357	8	morphogenesis	morphogenesis	NN
cord-260708-l9w5jhsw	357	9	of	of	IN
cord-260708-l9w5jhsw	357	10	Nairobi	Nairobi	NNP
cord-260708-l9w5jhsw	357	11	sheep	sheep	NN
cord-260708-l9w5jhsw	357	12	disease	disease	NN
cord-260708-l9w5jhsw	357	13	virus	virus	NN
cord-260708-l9w5jhsw	357	14	,	,	,
cord-260708-l9w5jhsw	358	1	a	a	DT
cord-260708-l9w5jhsw	358	2	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	358	3	Antiviral	Antiviral	NNP
cord-260708-l9w5jhsw	358	4	actions	action	NNS
cord-260708-l9w5jhsw	358	5	of	of	IN
cord-260708-l9w5jhsw	358	6	interferons	interferon	NNS
cord-260708-l9w5jhsw	358	7	Characterization	characterization	NN
cord-260708-l9w5jhsw	358	8	of	of	IN
cord-260708-l9w5jhsw	358	9	the	the	DT
cord-260708-l9w5jhsw	358	10	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	358	11	of	of	IN
cord-260708-l9w5jhsw	358	12	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	358	13	-	-	HYPH
cord-260708-l9w5jhsw	358	14	Congo	Congo	NNP
cord-260708-l9w5jhsw	358	15	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	358	16	fever	fever	NN
cord-260708-l9w5jhsw	358	17	virus	virus	NN
cord-260708-l9w5jhsw	358	18	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	358	19	-	-	HYPH
cord-260708-l9w5jhsw	358	20	congo	congo	NNP
cord-260708-l9w5jhsw	358	21	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	358	22	fever	fever	NN
cord-260708-l9w5jhsw	358	23	virus	virus	NN
cord-260708-l9w5jhsw	358	24	glycoprotein	glycoprotein	NN
cord-260708-l9w5jhsw	358	25	precursor	precursor	NN
cord-260708-l9w5jhsw	358	26	is	be	VBZ
cord-260708-l9w5jhsw	358	27	cleaved	cleave	VBN
cord-260708-l9w5jhsw	358	28	by	by	IN
cord-260708-l9w5jhsw	358	29	Furin	Furin	NNP
cord-260708-l9w5jhsw	358	30	-	-	HYPH
cord-260708-l9w5jhsw	358	31	like	like	JJ
cord-260708-l9w5jhsw	358	32	and	and	CC
cord-260708-l9w5jhsw	358	33	SKI-1	SKI-1	NNP
cord-260708-l9w5jhsw	358	34	proteases	protease	NNS
cord-260708-l9w5jhsw	358	35	to	to	TO
cord-260708-l9w5jhsw	358	36	generate	generate	VB
cord-260708-l9w5jhsw	358	37	a	a	DT
cord-260708-l9w5jhsw	358	38	novel	novel	JJ
cord-260708-l9w5jhsw	358	39	38-kilodalton	38-kilodalton	CD
cord-260708-l9w5jhsw	358	40	glycoprotein	glycoprotein	NN
cord-260708-l9w5jhsw	358	41	Tickborne	Tickborne	NNP
cord-260708-l9w5jhsw	358	42	arbovirus	arbovirus	NN
cord-260708-l9w5jhsw	358	43	surveillance	surveillance	NN
cord-260708-l9w5jhsw	358	44	in	in	IN
cord-260708-l9w5jhsw	358	45	market	market	NN
cord-260708-l9w5jhsw	358	46	livestock	livestock	NN
cord-260708-l9w5jhsw	358	47	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	358	48	:	:	:
cord-260708-l9w5jhsw	358	49	the	the	DT
cord-260708-l9w5jhsw	358	50	viruses	virus	NNS
cord-260708-l9w5jhsw	358	51	and	and	CC
cord-260708-l9w5jhsw	358	52	their	-PRON-	PRP$
cord-260708-l9w5jhsw	358	53	replication	replication	NN
cord-260708-l9w5jhsw	359	1	The	the	DT
cord-260708-l9w5jhsw	359	2	V3	V3	NNP
cord-260708-l9w5jhsw	359	3	loop	loop	NN
cord-260708-l9w5jhsw	359	4	-	-	HYPH
cord-260708-l9w5jhsw	359	5	mimicking	mimic	VBG
cord-260708-l9w5jhsw	359	6	pseudopeptide	pseudopeptide	NN
cord-260708-l9w5jhsw	359	7	5[Kpsi(CH2N)PR]-TASP	5[Kpsi(CH2N)PR]-TASP	NNP
cord-260708-l9w5jhsw	359	8	inhibits	inhibit	VBZ
cord-260708-l9w5jhsw	359	9	HIV	HIV	NNP
cord-260708-l9w5jhsw	359	10	infection	infection	NN
cord-260708-l9w5jhsw	359	11	in	in	IN
cord-260708-l9w5jhsw	359	12	primary	primary	JJ
cord-260708-l9w5jhsw	359	13	macrophage	macrophage	NN
cord-260708-l9w5jhsw	359	14	cultures	culture	NNS
cord-260708-l9w5jhsw	360	1	A	a	DT
cord-260708-l9w5jhsw	360	2	protein	protein	NN
cord-260708-l9w5jhsw	360	3	partially	partially	RB
cord-260708-l9w5jhsw	360	4	expressed	express	VBD
cord-260708-l9w5jhsw	360	5	on	on	IN
cord-260708-l9w5jhsw	360	6	the	the	DT
cord-260708-l9w5jhsw	360	7	surface	surface	NN
cord-260708-l9w5jhsw	360	8	of	of	IN
cord-260708-l9w5jhsw	360	9	HepG2	HepG2	NNP
cord-260708-l9w5jhsw	360	10	cells	cell	NNS
cord-260708-l9w5jhsw	360	11	that	that	WDT
cord-260708-l9w5jhsw	360	12	binds	bind	VBZ
cord-260708-l9w5jhsw	360	13	lipoproteins	lipoprotein	NNS
cord-260708-l9w5jhsw	360	14	specifically	specifically	RB
cord-260708-l9w5jhsw	360	15	is	be	VBZ
cord-260708-l9w5jhsw	361	1	nucleolin	nucleolin	NNP
cord-260708-l9w5jhsw	361	2	Essential	essential	JJ
cord-260708-l9w5jhsw	361	3	amino	amino	NN
cord-260708-l9w5jhsw	361	4	acids	acid	NNS
cord-260708-l9w5jhsw	361	5	of	of	IN
cord-260708-l9w5jhsw	361	6	the	the	DT
cord-260708-l9w5jhsw	361	7	hantaan	hantaan	NNP
cord-260708-l9w5jhsw	361	8	virus	virus	NN
cord-260708-l9w5jhsw	361	9	N	n	CD
cord-260708-l9w5jhsw	361	10	protein	protein	NN
cord-260708-l9w5jhsw	361	11	in	in	IN
cord-260708-l9w5jhsw	361	12	its	-PRON-	PRP$
cord-260708-l9w5jhsw	361	13	interaction	interaction	NN
cord-260708-l9w5jhsw	361	14	with	with	IN
cord-260708-l9w5jhsw	361	15	RNA	RNA	NNP
cord-260708-l9w5jhsw	361	16	Nucleolin	Nucleolin	NNP
cord-260708-l9w5jhsw	361	17	is	be	VBZ
cord-260708-l9w5jhsw	361	18	a	a	DT
cord-260708-l9w5jhsw	361	19	receptor	receptor	NN
cord-260708-l9w5jhsw	361	20	that	that	WDT
cord-260708-l9w5jhsw	361	21	mediates	mediate	VBZ
cord-260708-l9w5jhsw	361	22	antiangiogenic	antiangiogenic	JJ
cord-260708-l9w5jhsw	361	23	and	and	CC
cord-260708-l9w5jhsw	361	24	antitumor	antitumor	JJ
cord-260708-l9w5jhsw	361	25	activity	activity	NN
cord-260708-l9w5jhsw	361	26	of	of	IN
cord-260708-l9w5jhsw	361	27	endostatin	endostatin	NNP
cord-260708-l9w5jhsw	361	28	Surface	Surface	NNP
cord-260708-l9w5jhsw	361	29	expression	expression	NN
cord-260708-l9w5jhsw	361	30	of	of	IN
cord-260708-l9w5jhsw	361	31	MHC	MHC	NNP
cord-260708-l9w5jhsw	361	32	class	class	NN
cord-260708-l9w5jhsw	361	33	II	II	NNP
cord-260708-l9w5jhsw	361	34	in	in	IN
cord-260708-l9w5jhsw	361	35	dendritic	dendritic	JJ
cord-260708-l9w5jhsw	361	36	cells	cell	NNS
cord-260708-l9w5jhsw	361	37	is	be	VBZ
cord-260708-l9w5jhsw	361	38	controlled	control	VBN
cord-260708-l9w5jhsw	361	39	by	by	IN
cord-260708-l9w5jhsw	361	40	regulated	regulate	VBN
cord-260708-l9w5jhsw	361	41	ubiquitination	ubiquitination	NN
cord-260708-l9w5jhsw	361	42	Dissecting	dissect	VBG
cord-260708-l9w5jhsw	361	43	virus	virus	NN
cord-260708-l9w5jhsw	361	44	entry	entry	NN
cord-260708-l9w5jhsw	361	45	via	via	IN
cord-260708-l9w5jhsw	361	46	endocytosis	endocytosis	NN
cord-260708-l9w5jhsw	361	47	Ebola	Ebola	NNP
cord-260708-l9w5jhsw	361	48	virus	virus	NN
cord-260708-l9w5jhsw	361	49	glycoproteins	glycoprotein	NNS
cord-260708-l9w5jhsw	361	50	induce	induce	VBP
cord-260708-l9w5jhsw	361	51	global	global	JJ
cord-260708-l9w5jhsw	361	52	surface	surface	NN
cord-260708-l9w5jhsw	361	53	protein	protein	NN
cord-260708-l9w5jhsw	361	54	down	down	IN
cord-260708-l9w5jhsw	361	55	-	-	HYPH
cord-260708-l9w5jhsw	361	56	modulation	modulation	NN
cord-260708-l9w5jhsw	361	57	and	and	CC
cord-260708-l9w5jhsw	361	58	loss	loss	NN
cord-260708-l9w5jhsw	361	59	of	of	IN
cord-260708-l9w5jhsw	361	60	cell	cell	NN
cord-260708-l9w5jhsw	361	61	adherence	adherence	NN
cord-260708-l9w5jhsw	361	62	Microtubule	Microtubule	NNP
cord-260708-l9w5jhsw	361	63	-	-	HYPH
cord-260708-l9w5jhsw	361	64	dependent	dependent	JJ
cord-260708-l9w5jhsw	361	65	and	and	CC
cord-260708-l9w5jhsw	361	66	microtubule	microtubule	JJ
cord-260708-l9w5jhsw	361	67	-	-	HYPH
cord-260708-l9w5jhsw	361	68	independent	independent	JJ
cord-260708-l9w5jhsw	361	69	steps	step	NNS
cord-260708-l9w5jhsw	361	70	in	in	IN
cord-260708-l9w5jhsw	361	71	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	361	72	-	-	HYPH
cord-260708-l9w5jhsw	361	73	Congo	Congo	NNP
cord-260708-l9w5jhsw	361	74	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	361	75	fever	fever	NN
cord-260708-l9w5jhsw	361	76	virus	virus	NN
cord-260708-l9w5jhsw	361	77	replication	replication	NN
cord-260708-l9w5jhsw	361	78	cycle	cycle	NN
cord-260708-l9w5jhsw	361	79	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	361	80	-	-	HYPH
cord-260708-l9w5jhsw	361	81	Congo	Congo	NNP
cord-260708-l9w5jhsw	361	82	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	361	83	fever	fever	NN
cord-260708-l9w5jhsw	361	84	virus	virus	NN
cord-260708-l9w5jhsw	361	85	entry	entry	NN
cord-260708-l9w5jhsw	361	86	and	and	CC
cord-260708-l9w5jhsw	361	87	replication	replication	NN
cord-260708-l9w5jhsw	361	88	is	be	VBZ
cord-260708-l9w5jhsw	361	89	clathrin-	clathrin-	JJ
cord-260708-l9w5jhsw	361	90	,	,	,
cord-260708-l9w5jhsw	362	1	pHand	phand	JJ
cord-260708-l9w5jhsw	362	2	cholesterol	cholesterol	NN
cord-260708-l9w5jhsw	362	3	-	-	HYPH
cord-260708-l9w5jhsw	362	4	dependent	dependent	JJ
cord-260708-l9w5jhsw	362	5	Ubiquitylation	Ubiquitylation	NNP
cord-260708-l9w5jhsw	362	6	and	and	CC
cord-260708-l9w5jhsw	362	7	isgylation	isgylation	NN
cord-260708-l9w5jhsw	362	8	:	:	:
cord-260708-l9w5jhsw	362	9	overlapping	overlap	VBG
cord-260708-l9w5jhsw	362	10	enzymatic	enzymatic	JJ
cord-260708-l9w5jhsw	362	11	cascades	cascade	NNS
cord-260708-l9w5jhsw	362	12	do	do	VBP
cord-260708-l9w5jhsw	362	13	the	the	DT
cord-260708-l9w5jhsw	362	14	job	job	NN
cord-260708-l9w5jhsw	362	15	Epidemiology	epidemiology	NN
cord-260708-l9w5jhsw	362	16	and	and	CC
cord-260708-l9w5jhsw	362	17	phylogenetic	phylogenetic	JJ
cord-260708-l9w5jhsw	362	18	analysis	analysis	NN
cord-260708-l9w5jhsw	362	19	of	of	IN
cord-260708-l9w5jhsw	362	20	crimean	crimean	NNP
cord-260708-l9w5jhsw	362	21	-	-	HYPH
cord-260708-l9w5jhsw	362	22	congo	congo	NNP
cord-260708-l9w5jhsw	362	23	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	362	24	fever	fever	NN
cord-260708-l9w5jhsw	362	25	viruses	virus	NNS
cord-260708-l9w5jhsw	362	26	in	in	IN
cord-260708-l9w5jhsw	362	27	xinjiang	xinjiang	NNP
cord-260708-l9w5jhsw	362	28	DNA	DNA	NNP
cord-260708-l9w5jhsw	363	1	Topoisomerase	Topoisomerase	NNP
cord-260708-l9w5jhsw	363	2	1	1	CD
cord-260708-l9w5jhsw	363	3	Facilitates	facilitate	VBZ
cord-260708-l9w5jhsw	363	4	the	the	DT
cord-260708-l9w5jhsw	363	5	Transcription	Transcription	NNP
cord-260708-l9w5jhsw	363	6	and	and	CC
cord-260708-l9w5jhsw	363	7	Replication	Replication	NNP
cord-260708-l9w5jhsw	363	8	of	of	IN
cord-260708-l9w5jhsw	363	9	the	the	DT
cord-260708-l9w5jhsw	363	10	Ebola	Ebola	NNP
cord-260708-l9w5jhsw	363	11	Virus	Virus	NNP
cord-260708-l9w5jhsw	363	12	Genome	Genome	NNP
cord-260708-l9w5jhsw	363	13	Oligomerization	Oligomerization	NNP
cord-260708-l9w5jhsw	363	14	paths	path	NNS
cord-260708-l9w5jhsw	363	15	of	of	IN
cord-260708-l9w5jhsw	363	16	the	the	DT
cord-260708-l9w5jhsw	363	17	nucleoprotein	nucleoprotein	NNP
cord-260708-l9w5jhsw	363	18	of	of	IN
cord-260708-l9w5jhsw	363	19	influenza	influenza	NN
cord-260708-l9w5jhsw	363	20	A	a	DT
cord-260708-l9w5jhsw	363	21	virus	virus	NN
cord-260708-l9w5jhsw	363	22	Molecular	Molecular	NNP
cord-260708-l9w5jhsw	363	23	dynamics	dynamic	NNS
cord-260708-l9w5jhsw	363	24	studies	study	NNS
cord-260708-l9w5jhsw	363	25	of	of	IN
cord-260708-l9w5jhsw	363	26	the	the	DT
cord-260708-l9w5jhsw	363	27	nucleoprotein	nucleoprotein	NNP
cord-260708-l9w5jhsw	363	28	of	of	IN
cord-260708-l9w5jhsw	363	29	influenza	influenza	NN
cord-260708-l9w5jhsw	363	30	A	a	DT
cord-260708-l9w5jhsw	363	31	virus	virus	NN
cord-260708-l9w5jhsw	363	32	:	:	:
cord-260708-l9w5jhsw	363	33	role	role	NN
cord-260708-l9w5jhsw	363	34	of	of	IN
cord-260708-l9w5jhsw	363	35	the	the	DT
cord-260708-l9w5jhsw	363	36	protein	protein	NN
cord-260708-l9w5jhsw	363	37	flexibility	flexibility	NN
cord-260708-l9w5jhsw	363	38	in	in	IN
cord-260708-l9w5jhsw	363	39	RNA	RNA	NNP
cord-260708-l9w5jhsw	363	40	binding	bind	VBG
cord-260708-l9w5jhsw	363	41	Identification	Identification	NNP
cord-260708-l9w5jhsw	363	42	of	of	IN
cord-260708-l9w5jhsw	363	43	nucleolin	nucleolin	NNP
cord-260708-l9w5jhsw	363	44	as	as	IN
cord-260708-l9w5jhsw	363	45	a	a	DT
cord-260708-l9w5jhsw	363	46	cellular	cellular	JJ
cord-260708-l9w5jhsw	363	47	receptor	receptor	NN
cord-260708-l9w5jhsw	363	48	for	for	IN
cord-260708-l9w5jhsw	363	49	human	human	JJ
cord-260708-l9w5jhsw	363	50	respiratory	respiratory	JJ
cord-260708-l9w5jhsw	363	51	syncytial	syncytial	JJ
cord-260708-l9w5jhsw	363	52	virus	virus	NN
cord-260708-l9w5jhsw	363	53	NFkappaB	NFkappaB	NNP
cord-260708-l9w5jhsw	363	54	pathway	pathway	NN
cord-260708-l9w5jhsw	363	55	:	:	:
cord-260708-l9w5jhsw	363	56	a	a	DT
cord-260708-l9w5jhsw	363	57	good	good	JJ
cord-260708-l9w5jhsw	363	58	signaling	signal	VBG
cord-260708-l9w5jhsw	363	59	paradigm	paradigm	NN
cord-260708-l9w5jhsw	363	60	and	and	CC
cord-260708-l9w5jhsw	363	61	therapeutic	therapeutic	JJ
cord-260708-l9w5jhsw	363	62	target	target	NN
cord-260708-l9w5jhsw	363	63	Sequence	sequence	NN
cord-260708-l9w5jhsw	363	64	motifs	motif	NNS
cord-260708-l9w5jhsw	363	65	characteristic	characteristic	JJ
cord-260708-l9w5jhsw	363	66	for	for	IN
cord-260708-l9w5jhsw	363	67	DNA	dna	NN
cord-260708-l9w5jhsw	363	68	[	[	-LRB-
cord-260708-l9w5jhsw	363	69	cytosine	cytosine	NN
cord-260708-l9w5jhsw	363	70	-	-	HYPH
cord-260708-l9w5jhsw	363	71	N4	n4	NN
cord-260708-l9w5jhsw	363	72	]	]	-RRB-
cord-260708-l9w5jhsw	363	73	and	and	CC
cord-260708-l9w5jhsw	363	74	DNA	dna	NN
cord-260708-l9w5jhsw	363	75	[	[	-LRB-
cord-260708-l9w5jhsw	363	76	adenine	adenine	NN
cord-260708-l9w5jhsw	363	77	-	-	HYPH
cord-260708-l9w5jhsw	363	78	N6	n6	NN
cord-260708-l9w5jhsw	363	79	]	]	-RRB-
cord-260708-l9w5jhsw	363	80	methyltransferases	methyltransferase	NNS
cord-260708-l9w5jhsw	363	81	.	.	.
cord-260708-l9w5jhsw	364	1	Classification	classification	NN
cord-260708-l9w5jhsw	364	2	of	of	IN
cord-260708-l9w5jhsw	364	3	all	all	DT
cord-260708-l9w5jhsw	364	4	DNA	dna	NN
cord-260708-l9w5jhsw	364	5	methyltransferases	methyltransferase	NNS
cord-260708-l9w5jhsw	365	1	Thunderclap	thunderclap	NN
cord-260708-l9w5jhsw	365	2	headache	headache	NN
cord-260708-l9w5jhsw	365	3	caused	cause	VBN
cord-260708-l9w5jhsw	365	4	by	by	IN
cord-260708-l9w5jhsw	365	5	Erve	Erve	NNP
cord-260708-l9w5jhsw	365	6	virus	virus	NN
cord-260708-l9w5jhsw	366	1	Different	different	JJ
cord-260708-l9w5jhsw	366	2	modes	mode	NNS
cord-260708-l9w5jhsw	366	3	of	of	IN
cord-260708-l9w5jhsw	366	4	ubiquitination	ubiquitination	NN
cord-260708-l9w5jhsw	366	5	of	of	IN
cord-260708-l9w5jhsw	366	6	the	the	DT
cord-260708-l9w5jhsw	366	7	adaptor	adaptor	NN
cord-260708-l9w5jhsw	366	8	TRAF3	TRAF3	NNP
cord-260708-l9w5jhsw	366	9	selectively	selectively	RB
cord-260708-l9w5jhsw	366	10	activate	activate	VBP
cord-260708-l9w5jhsw	366	11	the	the	DT
cord-260708-l9w5jhsw	366	12	expression	expression	NN
cord-260708-l9w5jhsw	366	13	of	of	IN
cord-260708-l9w5jhsw	366	14	type	type	NN
cord-260708-l9w5jhsw	366	15	I	-PRON-	PRP
cord-260708-l9w5jhsw	366	16	interferons	interferon	NNS
cord-260708-l9w5jhsw	366	17	and	and	CC
cord-260708-l9w5jhsw	366	18	proinflammatory	proinflammatory	JJ
cord-260708-l9w5jhsw	366	19	cytokines	cytokine	NNS
cord-260708-l9w5jhsw	366	20	General	General	NNP
cord-260708-l9w5jhsw	366	21	review	review	NN
cord-260708-l9w5jhsw	366	22	of	of	IN
cord-260708-l9w5jhsw	366	23	tick	tick	NN
cord-260708-l9w5jhsw	366	24	-	-	HYPH
cord-260708-l9w5jhsw	366	25	borne	bear	VBN
cord-260708-l9w5jhsw	366	26	diseases	disease	NNS
cord-260708-l9w5jhsw	366	27	of	of	IN
cord-260708-l9w5jhsw	366	28	sheep	sheep	NNS
cord-260708-l9w5jhsw	366	29	and	and	CC
cord-260708-l9w5jhsw	366	30	goats	goat	NNS
cord-260708-l9w5jhsw	366	31	world	world	NN
cord-260708-l9w5jhsw	366	32	-	-	HYPH
cord-260708-l9w5jhsw	366	33	wide	wide	JJ
cord-260708-l9w5jhsw	366	34	Arterivirus	Arterivirus	NNP
cord-260708-l9w5jhsw	366	35	and	and	CC
cord-260708-l9w5jhsw	366	36	nairovirus	nairovirus	NNP
cord-260708-l9w5jhsw	366	37	ovarian	ovarian	JJ
cord-260708-l9w5jhsw	366	38	tumor	tumor	NN
cord-260708-l9w5jhsw	366	39	domain	domain	NN
cord-260708-l9w5jhsw	366	40	-	-	:
cord-260708-l9w5jhsw	366	41	containing	contain	VBG
cord-260708-l9w5jhsw	366	42	Deubiquitinases	Deubiquitinases	NNP
cord-260708-l9w5jhsw	366	43	target	target	NN
cord-260708-l9w5jhsw	366	44	activated	activate	VBN
cord-260708-l9w5jhsw	366	45	RIG	rig	NN
cord-260708-l9w5jhsw	366	46	-	-	:
cord-260708-l9w5jhsw	366	47	I	i	NN
cord-260708-l9w5jhsw	366	48	to	to	TO
cord-260708-l9w5jhsw	366	49	control	control	VB
cord-260708-l9w5jhsw	366	50	innate	innate	JJ
cord-260708-l9w5jhsw	366	51	immune	immune	NN
cord-260708-l9w5jhsw	366	52	signaling	signal	VBG
cord-260708-l9w5jhsw	366	53	Uncovering	uncover	VBG
cord-260708-l9w5jhsw	366	54	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	366	55	and	and	CC
cord-260708-l9w5jhsw	366	56	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	366	57	-	-	HYPH
cord-260708-l9w5jhsw	366	58	like	like	JJ
cord-260708-l9w5jhsw	366	59	signaling	signaling	NN
cord-260708-l9w5jhsw	366	60	networks	network	NNS
cord-260708-l9w5jhsw	366	61	Sequence	sequence	NN
cord-260708-l9w5jhsw	366	62	analysis	analysis	NN
cord-260708-l9w5jhsw	366	63	of	of	IN
cord-260708-l9w5jhsw	366	64	L	L	NNP
cord-260708-l9w5jhsw	366	65	RNA	RNA	NNP
cord-260708-l9w5jhsw	366	66	of	of	IN
cord-260708-l9w5jhsw	366	67	Lassa	Lassa	NNP
cord-260708-l9w5jhsw	366	68	virus	virus	NN
cord-260708-l9w5jhsw	366	69	Virus	virus	NN
cord-260708-l9w5jhsw	366	70	glycosylation	glycosylation	NN
cord-260708-l9w5jhsw	366	71	:	:	:
cord-260708-l9w5jhsw	366	72	role	role	NN
cord-260708-l9w5jhsw	366	73	in	in	IN
cord-260708-l9w5jhsw	366	74	virulence	virulence	NN
cord-260708-l9w5jhsw	366	75	and	and	CC
cord-260708-l9w5jhsw	366	76	immune	immune	JJ
cord-260708-l9w5jhsw	366	77	interactions	interaction	NNS
cord-260708-l9w5jhsw	366	78	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	366	79	-	-	HYPH
cord-260708-l9w5jhsw	366	80	Congo	Congo	NNP
cord-260708-l9w5jhsw	366	81	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	366	82	fever	fever	NN
cord-260708-l9w5jhsw	366	83	virus	virus	NN
cord-260708-l9w5jhsw	366	84	glycoprotein	glycoprotein	NN
cord-260708-l9w5jhsw	366	85	proteolytic	proteolytic	JJ
cord-260708-l9w5jhsw	366	86	processing	processing	NN
cord-260708-l9w5jhsw	366	87	by	by	IN
cord-260708-l9w5jhsw	366	88	subtilase	subtilase	NNP
cord-260708-l9w5jhsw	366	89	SKI	SKI	NNP
cord-260708-l9w5jhsw	367	1	The	the	DT
cord-260708-l9w5jhsw	367	2	inner	inner	JJ
cord-260708-l9w5jhsw	367	3	structure	structure	NN
cord-260708-l9w5jhsw	367	4	of	of	IN
cord-260708-l9w5jhsw	367	5	Uukuniemi	Uukuniemi	NNP
cord-260708-l9w5jhsw	367	6	and	and	CC
cord-260708-l9w5jhsw	367	7	two	two	CD
cord-260708-l9w5jhsw	367	8	Bunyamwera	Bunyamwera	NNP
cord-260708-l9w5jhsw	367	9	supergroup	supergroup	NN
cord-260708-l9w5jhsw	367	10	arboviruses	arboviruses	NNP
cord-260708-l9w5jhsw	367	11	Structure	Structure	NNP
cord-260708-l9w5jhsw	367	12	of	of	IN
cord-260708-l9w5jhsw	367	13	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	367	14	-	-	HYPH
cord-260708-l9w5jhsw	367	15	Congo	Congo	NNP
cord-260708-l9w5jhsw	367	16	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	367	17	fever	fever	NN
cord-260708-l9w5jhsw	367	18	virus	virus	NN
cord-260708-l9w5jhsw	367	19	nucleoprotein	nucleoprotein	NNP
cord-260708-l9w5jhsw	367	20	:	:	:
cord-260708-l9w5jhsw	367	21	superhelical	superhelical	NNP
cord-260708-l9w5jhsw	367	22	homooligomers	homooligomer	NNS
cord-260708-l9w5jhsw	367	23	and	and	CC
cord-260708-l9w5jhsw	367	24	the	the	DT
cord-260708-l9w5jhsw	367	25	role	role	NN
cord-260708-l9w5jhsw	367	26	of	of	IN
cord-260708-l9w5jhsw	367	27	caspase-3	caspase-3	NNP
cord-260708-l9w5jhsw	367	28	cleavage	cleavage	NN
cord-260708-l9w5jhsw	368	1	The	the	DT
cord-260708-l9w5jhsw	368	2	proteins	protein	NNS
cord-260708-l9w5jhsw	368	3	and	and	CC
cord-260708-l9w5jhsw	368	4	RNAs	rna	NNS
cord-260708-l9w5jhsw	368	5	specified	specify	VBN
cord-260708-l9w5jhsw	368	6	by	by	IN
cord-260708-l9w5jhsw	368	7	Clo	Clo	NNP
cord-260708-l9w5jhsw	368	8	Mor	Mor	NNP
cord-260708-l9w5jhsw	368	9	virus	virus	NN
cord-260708-l9w5jhsw	368	10	,	,	,
cord-260708-l9w5jhsw	368	11	a	a	DT
cord-260708-l9w5jhsw	368	12	Scottish	Scottish	NNP
cord-260708-l9w5jhsw	368	13	Nairovirus	Nairovirus	NNP
cord-260708-l9w5jhsw	368	14	Synthesis	Synthesis	NNP
cord-260708-l9w5jhsw	368	15	of	of	IN
cord-260708-l9w5jhsw	368	16	bunyavirus	bunyavirus	NNP
cord-260708-l9w5jhsw	368	17	-	-	HYPH
cord-260708-l9w5jhsw	368	18	specific	specific	JJ
cord-260708-l9w5jhsw	368	19	proteins	protein	NNS
cord-260708-l9w5jhsw	368	20	in	in	IN
cord-260708-l9w5jhsw	368	21	a	a	DT
cord-260708-l9w5jhsw	368	22	continuous	continuous	JJ
cord-260708-l9w5jhsw	368	23	cell	cell	NN
cord-260708-l9w5jhsw	368	24	line	line	NN
cord-260708-l9w5jhsw	368	25	(	(	-LRB-
cord-260708-l9w5jhsw	368	26	XTC-2	xtc-2	NN
cord-260708-l9w5jhsw	368	27	)	)	-RRB-
cord-260708-l9w5jhsw	368	28	derived	derive	VBN
cord-260708-l9w5jhsw	368	29	from	from	IN
cord-260708-l9w5jhsw	368	30	Xenopus	Xenopus	NNP
cord-260708-l9w5jhsw	368	31	laevis	laevi	NNS
cord-260708-l9w5jhsw	369	1	Tensaw	Tensaw	NNP
cord-260708-l9w5jhsw	369	2	virus	virus	NN
cord-260708-l9w5jhsw	369	3	genome	genome	NN
cord-260708-l9w5jhsw	369	4	sequence	sequence	NN
cord-260708-l9w5jhsw	369	5	and	and	CC
cord-260708-l9w5jhsw	369	6	its	-PRON-	PRP$
cord-260708-l9w5jhsw	369	7	relation	relation	NN
cord-260708-l9w5jhsw	369	8	to	to	IN
cord-260708-l9w5jhsw	369	9	other	other	JJ
cord-260708-l9w5jhsw	369	10	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	369	11	Double	double	RB
cord-260708-l9w5jhsw	369	12	-	-	HYPH
cord-260708-l9w5jhsw	369	13	stranded	strand	VBN
cord-260708-l9w5jhsw	369	14	RNA	RNA	NNP
cord-260708-l9w5jhsw	369	15	is	be	VBZ
cord-260708-l9w5jhsw	369	16	produced	produce	VBN
cord-260708-l9w5jhsw	369	17	by	by	IN
cord-260708-l9w5jhsw	369	18	positive	positive	JJ
cord-260708-l9w5jhsw	369	19	-	-	HYPH
cord-260708-l9w5jhsw	369	20	strand	strand	NN
cord-260708-l9w5jhsw	369	21	RNA	RNA	NNP
cord-260708-l9w5jhsw	369	22	viruses	virus	NNS
cord-260708-l9w5jhsw	369	23	and	and	CC
cord-260708-l9w5jhsw	369	24	DNA	dna	NN
cord-260708-l9w5jhsw	369	25	viruses	virus	NNS
cord-260708-l9w5jhsw	369	26	but	but	CC
cord-260708-l9w5jhsw	369	27	not	not	RB
cord-260708-l9w5jhsw	369	28	in	in	IN
cord-260708-l9w5jhsw	369	29	detectable	detectable	JJ
cord-260708-l9w5jhsw	369	30	amounts	amount	NNS
cord-260708-l9w5jhsw	369	31	by	by	IN
cord-260708-l9w5jhsw	369	32	negative	negative	JJ
cord-260708-l9w5jhsw	369	33	-	-	HYPH
cord-260708-l9w5jhsw	369	34	strand	strand	NN
cord-260708-l9w5jhsw	369	35	RNA	RNA	NNP
cord-260708-l9w5jhsw	369	36	viruses	virus	NNS
cord-260708-l9w5jhsw	369	37	Interferon	interferon	NN
cord-260708-l9w5jhsw	369	38	and	and	CC
cord-260708-l9w5jhsw	369	39	cytokine	cytokine	NN
cord-260708-l9w5jhsw	369	40	responses	response	NNS
cord-260708-l9w5jhsw	369	41	to	to	IN
cord-260708-l9w5jhsw	369	42	Crimean	crimean	JJ
cord-260708-l9w5jhsw	369	43	Congo	Congo	NNP
cord-260708-l9w5jhsw	369	44	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	369	45	fever	fever	NN
cord-260708-l9w5jhsw	369	46	virus	virus	NN
cord-260708-l9w5jhsw	369	47	;	;	:
cord-260708-l9w5jhsw	369	48	an	an	DT
cord-260708-l9w5jhsw	369	49	emerging	emerge	VBG
cord-260708-l9w5jhsw	369	50	and	and	CC
cord-260708-l9w5jhsw	369	51	neglected	neglect	VBN
cord-260708-l9w5jhsw	369	52	viral	viral	JJ
cord-260708-l9w5jhsw	369	53	zonoosis	zonoosis	NN
cord-260708-l9w5jhsw	369	54	Ubiquitin	Ubiquitin	NNP
cord-260708-l9w5jhsw	369	55	and	and	CC
cord-260708-l9w5jhsw	369	56	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	369	57	-	-	HYPH
cord-260708-l9w5jhsw	369	58	like	like	JJ
cord-260708-l9w5jhsw	369	59	proteins	protein	NNS
cord-260708-l9w5jhsw	369	60	as	as	IN
cord-260708-l9w5jhsw	369	61	multifunctional	multifunctional	JJ
cord-260708-l9w5jhsw	369	62	signals	signal	NNS
cord-260708-l9w5jhsw	369	63	Nairobi	Nairobi	NNP
cord-260708-l9w5jhsw	369	64	Sheep	Sheep	NNP
cord-260708-l9w5jhsw	369	65	Disease	Disease	NNP
cord-260708-l9w5jhsw	369	66	.	.	.
cord-260708-l9w5jhsw	370	1	In	in	IN
cord-260708-l9w5jhsw	370	2	:	:	:
cord-260708-l9w5jhsw	370	3	7th	7th	JJ
cord-260708-l9w5jhsw	370	4	(	(	-LRB-
cord-260708-l9w5jhsw	370	5	ed	ed	NN
cord-260708-l9w5jhsw	370	6	)	)	-RRB-
cord-260708-l9w5jhsw	370	7	Foreign	Foreign	NNP
cord-260708-l9w5jhsw	370	8	Animal	Animal	NNP
cord-260708-l9w5jhsw	370	9	Disease	Disease	NNP
cord-260708-l9w5jhsw	370	10	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	370	11	-	-	HYPH
cord-260708-l9w5jhsw	370	12	Congo	Congo	NNP
cord-260708-l9w5jhsw	370	13	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	370	14	fever	fever	NN
cord-260708-l9w5jhsw	370	15	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	370	16	-	-	HYPH
cord-260708-l9w5jhsw	370	17	congo	congo	NNP
cord-260708-l9w5jhsw	370	18	haemorrhagic	haemorrhagic	JJ
cord-260708-l9w5jhsw	370	19	fever	fever	NN
cord-260708-l9w5jhsw	370	20	:	:	:
cord-260708-l9w5jhsw	370	21	a	a	DT
cord-260708-l9w5jhsw	370	22	seroepidemiological	seroepidemiological	JJ
cord-260708-l9w5jhsw	370	23	and	and	CC
cord-260708-l9w5jhsw	370	24	tick	tick	VB
cord-260708-l9w5jhsw	370	25	survey	survey	NN
cord-260708-l9w5jhsw	370	26	in	in	IN
cord-260708-l9w5jhsw	370	27	the	the	DT
cord-260708-l9w5jhsw	370	28	Sultanate	Sultanate	NNP
cord-260708-l9w5jhsw	370	29	of	of	IN
cord-260708-l9w5jhsw	370	30	Oman	Oman	NNP
cord-260708-l9w5jhsw	371	1	The	the	DT
cord-260708-l9w5jhsw	371	2	Erve	Erve	NNP
cord-260708-l9w5jhsw	371	3	virus	virus	NN
cord-260708-l9w5jhsw	371	4	:	:	:
cord-260708-l9w5jhsw	371	5	possible	possible	JJ
cord-260708-l9w5jhsw	371	6	mode	mode	NN
cord-260708-l9w5jhsw	371	7	of	of	IN
cord-260708-l9w5jhsw	371	8	transmission	transmission	NN
cord-260708-l9w5jhsw	371	9	and	and	CC
cord-260708-l9w5jhsw	371	10	reservoir	reservoir	NN
cord-260708-l9w5jhsw	371	11	Identification	identification	NN
cord-260708-l9w5jhsw	371	12	of	of	IN
cord-260708-l9w5jhsw	371	13	a	a	DT
cord-260708-l9w5jhsw	371	14	putative	putative	JJ
cord-260708-l9w5jhsw	371	15	Crimean	Crimean	NNP
cord-260708-l9w5jhsw	371	16	-	-	HYPH
cord-260708-l9w5jhsw	371	17	Congo	Congo	NNP
cord-260708-l9w5jhsw	371	18	hemorrhagic	hemorrhagic	JJ
cord-260708-l9w5jhsw	371	19	fever	fever	NN
cord-260708-l9w5jhsw	371	20	virus	virus	NN
cord-260708-l9w5jhsw	371	21	entry	entry	NN
cord-260708-l9w5jhsw	371	22	factor	factor	NN
cord-260708-l9w5jhsw	371	23	Origin	Origin	NNP
cord-260708-l9w5jhsw	371	24	and	and	CC
cord-260708-l9w5jhsw	371	25	evolution	evolution	NN
cord-260708-l9w5jhsw	371	26	of	of	IN
cord-260708-l9w5jhsw	371	27	retroelements	retroelement	NNS
cord-260708-l9w5jhsw	371	28	based	base	VBN
cord-260708-l9w5jhsw	371	29	upon	upon	IN
cord-260708-l9w5jhsw	371	30	their	-PRON-	PRP$
cord-260708-l9w5jhsw	371	31	reverse	reverse	JJ
cord-260708-l9w5jhsw	371	32	transcriptase	transcriptase	NN
cord-260708-l9w5jhsw	371	33	sequences	sequence	NNS
cord-260708-l9w5jhsw	372	1	Genomic	genomic	JJ
cord-260708-l9w5jhsw	372	2	analysis	analysis	NN
cord-260708-l9w5jhsw	372	3	reveals	reveal	VBZ
cord-260708-l9w5jhsw	372	4	Nairobi	Nairobi	NNP
cord-260708-l9w5jhsw	372	5	sheep	sheep	NN
cord-260708-l9w5jhsw	372	6	disease	disease	NN
cord-260708-l9w5jhsw	372	7	virus	virus	NN
cord-260708-l9w5jhsw	372	8	to	to	TO
cord-260708-l9w5jhsw	372	9	be	be	VB
cord-260708-l9w5jhsw	372	10	highly	highly	RB
cord-260708-l9w5jhsw	372	11	diverse	diverse	JJ
cord-260708-l9w5jhsw	372	12	and	and	CC
cord-260708-l9w5jhsw	372	13	present	present	JJ
cord-260708-l9w5jhsw	372	14	in	in	IN
cord-260708-l9w5jhsw	372	15	both	both	CC
cord-260708-l9w5jhsw	372	16	Africa	Africa	NNP
cord-260708-l9w5jhsw	372	17	,	,	,
cord-260708-l9w5jhsw	372	18	and	and	CC
cord-260708-l9w5jhsw	372	19	in	in	IN
cord-260708-l9w5jhsw	372	20	India	India	NNP
cord-260708-l9w5jhsw	372	21	in	in	IN
cord-260708-l9w5jhsw	372	22	the	the	DT
cord-260708-l9w5jhsw	372	23	form	form	NN
cord-260708-l9w5jhsw	372	24	of	of	IN
cord-260708-l9w5jhsw	372	25	the	the	DT
cord-260708-l9w5jhsw	372	26	Ganjam	Ganjam	NNP
cord-260708-l9w5jhsw	372	27	virus	virus	NN
cord-260708-l9w5jhsw	372	28	variant	variant	NN
cord-260708-l9w5jhsw	372	29	Identification	identification	NN
cord-260708-l9w5jhsw	372	30	of	of	IN
cord-260708-l9w5jhsw	372	31	the	the	DT
cord-260708-l9w5jhsw	372	32	Ebola	Ebola	NNP
cord-260708-l9w5jhsw	372	33	virus	virus	NN
cord-260708-l9w5jhsw	372	34	glycoprotein	glycoprotein	NN
cord-260708-l9w5jhsw	372	35	as	as	IN
cord-260708-l9w5jhsw	372	36	the	the	DT
cord-260708-l9w5jhsw	372	37	main	main	JJ
cord-260708-l9w5jhsw	372	38	viral	viral	JJ
cord-260708-l9w5jhsw	372	39	determinant	determinant	NN
cord-260708-l9w5jhsw	372	40	of	of	IN
cord-260708-l9w5jhsw	372	41	vascular	vascular	JJ
cord-260708-l9w5jhsw	372	42	cell	cell	NN
cord-260708-l9w5jhsw	372	43	cytotoxicity	cytotoxicity	NN
cord-260708-l9w5jhsw	372	44	and	and	CC
cord-260708-l9w5jhsw	372	45	injury	injury	NN
cord-260708-l9w5jhsw	372	46	Crystal	Crystal	NNP
cord-260708-l9w5jhsw	372	47	structure	structure	NN
cord-260708-l9w5jhsw	372	48	of	of	IN
cord-260708-l9w5jhsw	372	49	an	an	DT
cord-260708-l9w5jhsw	372	50	avian	avian	JJ
cord-260708-l9w5jhsw	372	51	influenza	influenza	NN
cord-260708-l9w5jhsw	372	52	polymerase	polymerase	NN
cord-260708-l9w5jhsw	372	53	PA(N	pa(n	CD
cord-260708-l9w5jhsw	372	54	)	)	-RRB-
cord-260708-l9w5jhsw	372	55	reveals	reveal	VBZ
cord-260708-l9w5jhsw	372	56	an	an	DT
cord-260708-l9w5jhsw	372	57	endonuclease	endonuclease	NN
cord-260708-l9w5jhsw	372	58	active	active	JJ
cord-260708-l9w5jhsw	372	59	site	site	NN
cord-260708-l9w5jhsw	372	60	Electron	Electron	NNP
cord-260708-l9w5jhsw	372	61	microscopic	microscopic	JJ
cord-260708-l9w5jhsw	372	62	and	and	CC
cord-260708-l9w5jhsw	372	63	antigenic	antigenic	JJ
cord-260708-l9w5jhsw	372	64	studies	study	NNS
cord-260708-l9w5jhsw	372	65	of	of	IN
cord-260708-l9w5jhsw	372	66	uncharacterized	uncharacterized	JJ
cord-260708-l9w5jhsw	372	67	viruses	virus	NNS
cord-260708-l9w5jhsw	372	68	.	.	.
cord-260708-l9w5jhsw	373	1	II	II	NNP
cord-260708-l9w5jhsw	373	2	.	.	.
cord-260708-l9w5jhsw	374	1	Evidence	evidence	NN
cord-260708-l9w5jhsw	374	2	suggesting	suggest	VBG
cord-260708-l9w5jhsw	374	3	the	the	DT
cord-260708-l9w5jhsw	374	4	placement	placement	NN
cord-260708-l9w5jhsw	374	5	of	of	IN
cord-260708-l9w5jhsw	374	6	viruses	virus	NNS
cord-260708-l9w5jhsw	374	7	in	in	IN
cord-260708-l9w5jhsw	374	8	the	the	DT
cord-260708-l9w5jhsw	374	9	family	family	NN
cord-260708-l9w5jhsw	374	10	Bunyaviridae	Bunyaviridae	NNP
cord-260708-l9w5jhsw	375	1	The	the	DT
cord-260708-l9w5jhsw	375	2	UbcH8	UbcH8	NNP
cord-260708-l9w5jhsw	375	3	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	375	4	E2	e2	NN
cord-260708-l9w5jhsw	375	5	enzyme	enzyme	NN
cord-260708-l9w5jhsw	375	6	is	be	VBZ
cord-260708-l9w5jhsw	375	7	also	also	RB
cord-260708-l9w5jhsw	375	8	the	the	DT
cord-260708-l9w5jhsw	375	9	E2	E2	NNP
cord-260708-l9w5jhsw	375	10	enzyme	enzyme	NN
cord-260708-l9w5jhsw	375	11	for	for	IN
cord-260708-l9w5jhsw	375	12	ISG15	ISG15	NNP
cord-260708-l9w5jhsw	375	13	,	,	,
cord-260708-l9w5jhsw	375	14	an	an	DT
cord-260708-l9w5jhsw	375	15	IFNalpha	ifnalpha	NN
cord-260708-l9w5jhsw	375	16	/	/	SYM
cord-260708-l9w5jhsw	375	17	beta	beta	NN
cord-260708-l9w5jhsw	375	18	-	-	HYPH
cord-260708-l9w5jhsw	375	19	induced	induce	VBN
cord-260708-l9w5jhsw	375	20	ubiquitin	ubiquitin	NN
cord-260708-l9w5jhsw	375	21	-	-	HYPH
cord-260708-l9w5jhsw	375	22	like	like	JJ
cord-260708-l9w5jhsw	375	23	protein	protein	NN
cord-260708-l9w5jhsw	375	24	Human	human	NN
cord-260708-l9w5jhsw	375	25	ISG15	isg15	NN
cord-260708-l9w5jhsw	375	26	conjugation	conjugation	NN
cord-260708-l9w5jhsw	375	27	targets	target	NNS
cord-260708-l9w5jhsw	375	28	both	both	CC
cord-260708-l9w5jhsw	375	29	IFN	IFN	NNP
cord-260708-l9w5jhsw	375	30	-	-	HYPH
cord-260708-l9w5jhsw	375	31	induced	induce	VBN
cord-260708-l9w5jhsw	375	32	and	and	CC
cord-260708-l9w5jhsw	375	33	constitutively	constitutively	RB
cord-260708-l9w5jhsw	375	34	expressed	express	VBD
cord-260708-l9w5jhsw	375	35	proteins	protein	NNS
cord-260708-l9w5jhsw	375	36	functioning	function	VBG
cord-260708-l9w5jhsw	375	37	in	in	IN
cord-260708-l9w5jhsw	375	38	diverse	diverse	JJ
cord-260708-l9w5jhsw	375	39	cellular	cellular	JJ
cord-260708-l9w5jhsw	375	40	pathways	pathway	NNS
cord-260708-l9w5jhsw	375	41	RNA	rna	NN
cord-260708-l9w5jhsw	375	42	-	-	HYPH
cord-260708-l9w5jhsw	375	43	binding	bind	VBG
cord-260708-l9w5jhsw	375	44	proteins	protein	NNS
cord-260708-l9w5jhsw	375	45	that	that	WDT
cord-260708-l9w5jhsw	375	46	inhibit	inhibit	VBP
cord-260708-l9w5jhsw	375	47	RNA	RNA	NNP
cord-260708-l9w5jhsw	375	48	virus	virus	NN
cord-260708-l9w5jhsw	375	49	infection	infection	NN
cord-260708-l9w5jhsw	375	50	Acknowledgments	acknowledgment	NNS
cord-260708-l9w5jhsw	376	1	The	the	DT
cord-260708-l9w5jhsw	376	2	laboratory	laboratory	NN
cord-260708-l9w5jhsw	376	3	of	of	IN
cord-260708-l9w5jhsw	376	4	MDB	MDB	NNP
cord-260708-l9w5jhsw	376	5	receives	receive	VBZ
cord-260708-l9w5jhsw	376	6	funding	funding	NN
cord-260708-l9w5jhsw	376	7	from	from	IN
cord-260708-l9w5jhsw	376	8	the	the	DT
cord-260708-l9w5jhsw	376	9	UK	UK	NNP
cord-260708-l9w5jhsw	376	10	Biotechnology	Biotechnology	NNP
cord-260708-l9w5jhsw	376	11	and	and	CC
cord-260708-l9w5jhsw	376	12	Biological	Biological	NNP
cord-260708-l9w5jhsw	376	13	Science	Science	NNP
cord-260708-l9w5jhsw	376	14	Research	Research	NNP
cord-260708-l9w5jhsw	376	15	Council	Council	NNP
cord-260708-l9w5jhsw	376	16	(	(	-LRB-
cord-260708-l9w5jhsw	376	17	BBSRC	BBSRC	NNP
cord-260708-l9w5jhsw	376	18	)	)	-RRB-
cord-260708-l9w5jhsw	376	19	.	.	.
cord-260708-l9w5jhsw	377	1	LL	LL	NNP
cord-260708-l9w5jhsw	377	2	was	be	VBD
cord-260708-l9w5jhsw	377	3	the	the	DT
cord-260708-l9w5jhsw	377	4	recipient	recipient	NN
cord-260708-l9w5jhsw	377	5	of	of	IN
cord-260708-l9w5jhsw	377	6	a	a	DT
cord-260708-l9w5jhsw	377	7	BBSRC	BBSRC	NNP
cord-260708-l9w5jhsw	377	8	PhD	phd	NN
cord-260708-l9w5jhsw	377	9	studentship	studentship	NN
cord-260708-l9w5jhsw	377	10	.	.	.