id	sid	tid	token	lemma	pos
cord-320092-0qnvydux	1	1	key	key	JJ
cord-320092-0qnvydux	1	2	:	:	:
cord-320092-0qnvydux	1	3	cord-320092	cord-320092	NN
cord-320092-0qnvydux	1	4	-	-	HYPH
cord-320092-0qnvydux	1	5	0qnvydux	0qnvydux	CD
cord-320092-0qnvydux	1	6	authors	author	NNS
cord-320092-0qnvydux	1	7	:	:	:
cord-320092-0qnvydux	1	8	Ehsani	Ehsani	NNP
cord-320092-0qnvydux	1	9	,	,	,
cord-320092-0qnvydux	1	10	Sepehr	Sepehr	NNP
cord-320092-0qnvydux	1	11	title	title	NN
cord-320092-0qnvydux	1	12	:	:	:
cord-320092-0qnvydux	1	13	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	1	14	and	and	CC
cord-320092-0qnvydux	1	15	iron	iron	NN
cord-320092-0qnvydux	1	16	dysregulation	dysregulation	NN
cord-320092-0qnvydux	1	17	:	:	:
cord-320092-0qnvydux	1	18	distant	distant	JJ
cord-320092-0qnvydux	1	19	sequence	sequence	NN
cord-320092-0qnvydux	1	20	similarity	similarity	NN
cord-320092-0qnvydux	1	21	between	between	IN
cord-320092-0qnvydux	1	22	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	1	23	and	and	CC
cord-320092-0qnvydux	1	24	the	the	DT
cord-320092-0qnvydux	1	25	novel	novel	JJ
cord-320092-0qnvydux	1	26	coronavirus	coronavirus	NN
cord-320092-0qnvydux	1	27	spike	spike	NN
cord-320092-0qnvydux	1	28	glycoprotein	glycoprotein	NN
cord-320092-0qnvydux	1	29	date	date	NN
cord-320092-0qnvydux	1	30	:	:	:
cord-320092-0qnvydux	1	31	2020	2020	CD
cord-320092-0qnvydux	1	32	-	-	SYM
cord-320092-0qnvydux	1	33	10	10	CD
cord-320092-0qnvydux	1	34	-	-	SYM
cord-320092-0qnvydux	1	35	16	16	CD
cord-320092-0qnvydux	1	36	journal	journal	NN
cord-320092-0qnvydux	1	37	:	:	:
cord-320092-0qnvydux	1	38	Biol	Biol	NNP
cord-320092-0qnvydux	1	39	Direct	Direct	NNP
cord-320092-0qnvydux	1	40	DOI	DOI	NNP
cord-320092-0qnvydux	1	41	:	:	:
cord-320092-0qnvydux	1	42	10.1186	10.1186	CD
cord-320092-0qnvydux	1	43	/	/	SYM
cord-320092-0qnvydux	1	44	s13062	s13062	CD
cord-320092-0qnvydux	1	45	-	-	HYPH
cord-320092-0qnvydux	1	46	020	020	CD
cord-320092-0qnvydux	1	47	-	-	HYPH
cord-320092-0qnvydux	1	48	00275	00275	CD
cord-320092-0qnvydux	1	49	-	-	SYM
cord-320092-0qnvydux	1	50	2	2	CD
cord-320092-0qnvydux	2	1	sha	sha	NNP
cord-320092-0qnvydux	2	2	:	:	:
cord-320092-0qnvydux	2	3	479110fb550d9d84d0e84814872c310618790c31	479110fb550d9d84d0e84814872c310618790c31	CD
cord-320092-0qnvydux	2	4	doc_id	doc_id	CD
cord-320092-0qnvydux	2	5	:	:	:
cord-320092-0qnvydux	2	6	320092	320092	CD
cord-320092-0qnvydux	2	7	cord_uid	cord_uid	NN
cord-320092-0qnvydux	2	8	:	:	:
cord-320092-0qnvydux	3	1	0qnvydux	0qnvydux	LS
cord-320092-0qnvydux	3	2	The	the	DT
cord-320092-0qnvydux	3	3	spike	spike	NN
cord-320092-0qnvydux	3	4	glycoprotein	glycoprotein	NN
cord-320092-0qnvydux	3	5	of	of	IN
cord-320092-0qnvydux	3	6	the	the	DT
cord-320092-0qnvydux	3	7	SARS	SARS	NNP
cord-320092-0qnvydux	3	8	-	-	HYPH
cord-320092-0qnvydux	3	9	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	3	10	virus	virus	NN
cord-320092-0qnvydux	3	11	,	,	,
cord-320092-0qnvydux	3	12	which	which	WDT
cord-320092-0qnvydux	3	13	causes	cause	VBZ
cord-320092-0qnvydux	3	14	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	3	15	,	,	,
cord-320092-0qnvydux	3	16	has	have	VBZ
cord-320092-0qnvydux	3	17	attracted	attract	VBN
cord-320092-0qnvydux	3	18	attention	attention	NN
cord-320092-0qnvydux	3	19	for	for	IN
cord-320092-0qnvydux	3	20	its	-PRON-	PRP$
cord-320092-0qnvydux	3	21	vaccine	vaccine	NN
cord-320092-0qnvydux	3	22	potential	potential	NN
cord-320092-0qnvydux	3	23	and	and	CC
cord-320092-0qnvydux	3	24	binding	binding	JJ
cord-320092-0qnvydux	3	25	capacity	capacity	NN
cord-320092-0qnvydux	3	26	to	to	TO
cord-320092-0qnvydux	3	27	host	host	VB
cord-320092-0qnvydux	3	28	cell	cell	NN
cord-320092-0qnvydux	3	29	surface	surface	NN
cord-320092-0qnvydux	3	30	receptors	receptor	NNS
cord-320092-0qnvydux	3	31	.	.	.
cord-320092-0qnvydux	4	1	Much	much	JJ
cord-320092-0qnvydux	4	2	of	of	IN
cord-320092-0qnvydux	4	3	this	this	DT
cord-320092-0qnvydux	4	4	research	research	NN
cord-320092-0qnvydux	4	5	focus	focus	NN
cord-320092-0qnvydux	4	6	has	have	VBZ
cord-320092-0qnvydux	4	7	centered	center	VBN
cord-320092-0qnvydux	4	8	on	on	IN
cord-320092-0qnvydux	4	9	the	the	DT
cord-320092-0qnvydux	4	10	ectodomain	ectodomain	NN
cord-320092-0qnvydux	4	11	of	of	IN
cord-320092-0qnvydux	4	12	the	the	DT
cord-320092-0qnvydux	4	13	spike	spike	NN
cord-320092-0qnvydux	4	14	protein	protein	NN
cord-320092-0qnvydux	4	15	.	.	.
cord-320092-0qnvydux	5	1	The	the	DT
cord-320092-0qnvydux	5	2	ectodomain	ectodomain	NN
cord-320092-0qnvydux	5	3	is	be	VBZ
cord-320092-0qnvydux	5	4	anchored	anchor	VBN
cord-320092-0qnvydux	5	5	to	to	IN
cord-320092-0qnvydux	5	6	a	a	DT
cord-320092-0qnvydux	5	7	transmembrane	transmembrane	NN
cord-320092-0qnvydux	5	8	region	region	NN
cord-320092-0qnvydux	5	9	,	,	,
cord-320092-0qnvydux	5	10	followed	follow	VBN
cord-320092-0qnvydux	5	11	by	by	IN
cord-320092-0qnvydux	5	12	a	a	DT
cord-320092-0qnvydux	5	13	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	5	14	tail	tail	NN
cord-320092-0qnvydux	5	15	.	.	.
cord-320092-0qnvydux	6	1	Here	here	RB
cord-320092-0qnvydux	6	2	we	-PRON-	PRP
cord-320092-0qnvydux	6	3	report	report	VBP
cord-320092-0qnvydux	6	4	a	a	DT
cord-320092-0qnvydux	6	5	distant	distant	JJ
cord-320092-0qnvydux	6	6	sequence	sequence	NN
cord-320092-0qnvydux	6	7	similarity	similarity	NN
cord-320092-0qnvydux	6	8	between	between	IN
cord-320092-0qnvydux	6	9	the	the	DT
cord-320092-0qnvydux	6	10	cysteine	cysteine	NN
cord-320092-0qnvydux	6	11	-	-	HYPH
cord-320092-0qnvydux	6	12	rich	rich	JJ
cord-320092-0qnvydux	6	13	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	6	14	tail	tail	NN
cord-320092-0qnvydux	6	15	of	of	IN
cord-320092-0qnvydux	6	16	the	the	DT
cord-320092-0qnvydux	6	17	coronavirus	coronavirus	NN
cord-320092-0qnvydux	6	18	spike	spike	NN
cord-320092-0qnvydux	6	19	protein	protein	NN
cord-320092-0qnvydux	6	20	and	and	CC
cord-320092-0qnvydux	6	21	the	the	DT
cord-320092-0qnvydux	6	22	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	6	23	protein	protein	NN
cord-320092-0qnvydux	6	24	that	that	WDT
cord-320092-0qnvydux	6	25	is	be	VBZ
cord-320092-0qnvydux	6	26	found	find	VBN
cord-320092-0qnvydux	6	27	in	in	IN
cord-320092-0qnvydux	6	28	humans	human	NNS
cord-320092-0qnvydux	6	29	and	and	CC
cord-320092-0qnvydux	6	30	other	other	JJ
cord-320092-0qnvydux	6	31	vertebrates	vertebrate	NNS
cord-320092-0qnvydux	6	32	.	.	.
cord-320092-0qnvydux	7	1	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	7	2	is	be	VBZ
cord-320092-0qnvydux	7	3	thought	think	VBN
cord-320092-0qnvydux	7	4	to	to	TO
cord-320092-0qnvydux	7	5	be	be	VB
cord-320092-0qnvydux	7	6	the	the	DT
cord-320092-0qnvydux	7	7	key	key	JJ
cord-320092-0qnvydux	7	8	regulator	regulator	NN
cord-320092-0qnvydux	7	9	of	of	IN
cord-320092-0qnvydux	7	10	iron	iron	NN
cord-320092-0qnvydux	7	11	metabolism	metabolism	NN
cord-320092-0qnvydux	7	12	in	in	IN
cord-320092-0qnvydux	7	13	humans	human	NNS
cord-320092-0qnvydux	7	14	through	through	IN
cord-320092-0qnvydux	7	15	its	-PRON-	PRP$
cord-320092-0qnvydux	7	16	inhibition	inhibition	NN
cord-320092-0qnvydux	7	17	of	of	IN
cord-320092-0qnvydux	7	18	the	the	DT
cord-320092-0qnvydux	7	19	iron	iron	NN
cord-320092-0qnvydux	7	20	-	-	HYPH
cord-320092-0qnvydux	7	21	exporting	export	VBG
cord-320092-0qnvydux	7	22	protein	protein	NN
cord-320092-0qnvydux	7	23	ferroportin	ferroportin	NNP
cord-320092-0qnvydux	7	24	.	.	.
cord-320092-0qnvydux	8	1	An	an	DT
cord-320092-0qnvydux	8	2	implication	implication	NN
cord-320092-0qnvydux	8	3	of	of	IN
cord-320092-0qnvydux	8	4	this	this	DT
cord-320092-0qnvydux	8	5	preliminary	preliminary	JJ
cord-320092-0qnvydux	8	6	observation	observation	NN
cord-320092-0qnvydux	8	7	is	be	VBZ
cord-320092-0qnvydux	8	8	to	to	TO
cord-320092-0qnvydux	8	9	suggest	suggest	VB
cord-320092-0qnvydux	8	10	a	a	DT
cord-320092-0qnvydux	8	11	potential	potential	JJ
cord-320092-0qnvydux	8	12	route	route	NN
cord-320092-0qnvydux	8	13	of	of	IN
cord-320092-0qnvydux	8	14	investigation	investigation	NN
cord-320092-0qnvydux	8	15	in	in	IN
cord-320092-0qnvydux	8	16	the	the	DT
cord-320092-0qnvydux	8	17	coronavirus	coronavirus	NN
cord-320092-0qnvydux	8	18	research	research	NN
cord-320092-0qnvydux	8	19	field	field	NN
cord-320092-0qnvydux	8	20	making	make	VBG
cord-320092-0qnvydux	8	21	use	use	NN
cord-320092-0qnvydux	8	22	of	of	IN
cord-320092-0qnvydux	8	23	an	an	DT
cord-320092-0qnvydux	8	24	already	already	RB
cord-320092-0qnvydux	8	25	-	-	HYPH
cord-320092-0qnvydux	8	26	established	establish	VBN
cord-320092-0qnvydux	8	27	literature	literature	NN
cord-320092-0qnvydux	8	28	on	on	IN
cord-320092-0qnvydux	8	29	the	the	DT
cord-320092-0qnvydux	8	30	interplay	interplay	NN
cord-320092-0qnvydux	8	31	of	of	IN
cord-320092-0qnvydux	8	32	local	local	JJ
cord-320092-0qnvydux	8	33	and	and	CC
cord-320092-0qnvydux	8	34	systemic	systemic	JJ
cord-320092-0qnvydux	8	35	iron	iron	NN
cord-320092-0qnvydux	8	36	regulation	regulation	NN
cord-320092-0qnvydux	8	37	,	,	,
cord-320092-0qnvydux	8	38	cytokine	cytokine	NN
cord-320092-0qnvydux	8	39	-	-	HYPH
cord-320092-0qnvydux	8	40	mediated	mediate	VBN
cord-320092-0qnvydux	8	41	inflammatory	inflammatory	JJ
cord-320092-0qnvydux	8	42	processes	process	NNS
cord-320092-0qnvydux	8	43	,	,	,
cord-320092-0qnvydux	8	44	respiratory	respiratory	JJ
cord-320092-0qnvydux	8	45	infections	infection	NNS
cord-320092-0qnvydux	8	46	and	and	CC
cord-320092-0qnvydux	8	47	the	the	DT
cord-320092-0qnvydux	8	48	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	8	49	protein	protein	NN
cord-320092-0qnvydux	8	50	.	.	.
cord-320092-0qnvydux	9	1	The	the	DT
cord-320092-0qnvydux	9	2	question	question	NN
cord-320092-0qnvydux	9	3	of	of	IN
cord-320092-0qnvydux	9	4	possible	possible	JJ
cord-320092-0qnvydux	9	5	homology	homology	NN
cord-320092-0qnvydux	9	6	and	and	CC
cord-320092-0qnvydux	9	7	an	an	DT
cord-320092-0qnvydux	9	8	evolutionary	evolutionary	JJ
cord-320092-0qnvydux	9	9	connection	connection	NN
cord-320092-0qnvydux	9	10	between	between	IN
cord-320092-0qnvydux	9	11	the	the	DT
cord-320092-0qnvydux	9	12	viral	viral	JJ
cord-320092-0qnvydux	9	13	spike	spike	NN
cord-320092-0qnvydux	9	14	protein	protein	NN
cord-320092-0qnvydux	9	15	and	and	CC
cord-320092-0qnvydux	9	16	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	9	17	is	be	VBZ
cord-320092-0qnvydux	9	18	not	not	RB
cord-320092-0qnvydux	9	19	assessed	assess	VBN
cord-320092-0qnvydux	9	20	in	in	IN
cord-320092-0qnvydux	9	21	this	this	DT
cord-320092-0qnvydux	9	22	report	report	NN
cord-320092-0qnvydux	9	23	,	,	,
cord-320092-0qnvydux	9	24	but	but	CC
cord-320092-0qnvydux	9	25	some	some	DT
cord-320092-0qnvydux	9	26	scenarios	scenario	NNS
cord-320092-0qnvydux	9	27	for	for	IN
cord-320092-0qnvydux	9	28	its	-PRON-	PRP$
cord-320092-0qnvydux	9	29	study	study	NN
cord-320092-0qnvydux	9	30	are	be	VBP
cord-320092-0qnvydux	9	31	discussed	discuss	VBN
cord-320092-0qnvydux	9	32	.	.	.
cord-320092-0qnvydux	10	1	(	(	-LRB-
cord-320092-0qnvydux	10	2	ACE2	ACE2	NNP
cord-320092-0qnvydux	10	3	)	)	-RRB-
cord-320092-0qnvydux	10	4	is	be	VBZ
cord-320092-0qnvydux	10	5	thought	think	VBN
cord-320092-0qnvydux	10	6	to	to	TO
cord-320092-0qnvydux	10	7	be	be	VB
cord-320092-0qnvydux	10	8	its	-PRON-	PRP$
cord-320092-0qnvydux	10	9	(	(	-LRB-
cord-320092-0qnvydux	10	10	main	main	JJ
cord-320092-0qnvydux	10	11	,	,	,
cord-320092-0qnvydux	10	12	but	but	CC
cord-320092-0qnvydux	10	13	perhaps	perhaps	RB
cord-320092-0qnvydux	10	14	not	not	RB
cord-320092-0qnvydux	10	15	exclusive	exclusive	JJ
cord-320092-0qnvydux	10	16	)	)	-RRB-
cord-320092-0qnvydux	10	17	receptor	receptor	NN
cord-320092-0qnvydux	10	18	on	on	IN
cord-320092-0qnvydux	10	19	human	human	JJ
cord-320092-0qnvydux	10	20	host	host	NN
cord-320092-0qnvydux	10	21	cells	cell	NNS
cord-320092-0qnvydux	10	22	[	[	-LRB-
cord-320092-0qnvydux	10	23	132	132	CD
cord-320092-0qnvydux	10	24	,	,	,
cord-320092-0qnvydux	10	25	136	136	CD
cord-320092-0qnvydux	10	26	]	]	-RRB-
cord-320092-0qnvydux	10	27	.	.	.
cord-320092-0qnvydux	11	1	The	the	DT
cord-320092-0qnvydux	11	2	spike	spike	NN
cord-320092-0qnvydux	11	3	protein	protein	NN
cord-320092-0qnvydux	11	4	is	be	VBZ
cord-320092-0qnvydux	11	5	formed	form	VBN
cord-320092-0qnvydux	11	6	of	of	IN
cord-320092-0qnvydux	11	7	a	a	DT
cord-320092-0qnvydux	11	8	receptor	receptor	NN
cord-320092-0qnvydux	11	9	-	-	HYPH
cord-320092-0qnvydux	11	10	binding	bind	VBG
cord-320092-0qnvydux	11	11	subunit	subunit	NN
cord-320092-0qnvydux	11	12	(	(	-LRB-
cord-320092-0qnvydux	11	13	S1	S1	NNP
cord-320092-0qnvydux	11	14	)	)	-RRB-
cord-320092-0qnvydux	11	15	,	,	,
cord-320092-0qnvydux	11	16	a	a	DT
cord-320092-0qnvydux	11	17	membrane	membrane	NN
cord-320092-0qnvydux	11	18	-	-	HYPH
cord-320092-0qnvydux	11	19	fusion	fusion	NN
cord-320092-0qnvydux	11	20	subunit	subunit	NN
cord-320092-0qnvydux	11	21	(	(	-LRB-
cord-320092-0qnvydux	11	22	S2	S2	NNP
cord-320092-0qnvydux	11	23	)	)	-RRB-
cord-320092-0qnvydux	11	24	,	,	,
cord-320092-0qnvydux	11	25	a	a	DT
cord-320092-0qnvydux	11	26	single	single	JJ
cord-320092-0qnvydux	11	27	-	-	HYPH
cord-320092-0qnvydux	11	28	pass	pass	NN
cord-320092-0qnvydux	11	29	transmembrane	transmembrane	NN
cord-320092-0qnvydux	11	30	(	(	-LRB-
cord-320092-0qnvydux	11	31	TM	TM	NNP
cord-320092-0qnvydux	11	32	)	)	-RRB-
cord-320092-0qnvydux	11	33	domain	domain	NN
cord-320092-0qnvydux	11	34	,	,	,
cord-320092-0qnvydux	11	35	and	and	CC
cord-320092-0qnvydux	11	36	a	a	DT
cord-320092-0qnvydux	11	37	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	11	38	/	/	SYM
cord-320092-0qnvydux	11	39	intracellular	intracellular	JJ
cord-320092-0qnvydux	11	40	tail	tail	NN
cord-320092-0qnvydux	11	41	(	(	-LRB-
cord-320092-0qnvydux	11	42	CT	CT	NNP
cord-320092-0qnvydux	11	43	)	)	-RRB-
cord-320092-0qnvydux	11	44	[	[	-LRB-
cord-320092-0qnvydux	11	45	75	75	CD
cord-320092-0qnvydux	11	46	,	,	,
cord-320092-0qnvydux	11	47	115	115	CD
cord-320092-0qnvydux	11	48	]	]	-RRB-
cord-320092-0qnvydux	11	49	.	.	.
cord-320092-0qnvydux	12	1	Of	of	IN
cord-320092-0qnvydux	12	2	note	note	NN
cord-320092-0qnvydux	12	3	,	,	,
cord-320092-0qnvydux	12	4	the	the	DT
cord-320092-0qnvydux	12	5	S1	S1	NNP
cord-320092-0qnvydux	12	6	domain	domain	NN
cord-320092-0qnvydux	12	7	has	have	VBZ
cord-320092-0qnvydux	12	8	a	a	DT
cord-320092-0qnvydux	12	9	similar	similar	JJ
cord-320092-0qnvydux	12	10	fold	fold	NN
cord-320092-0qnvydux	12	11	as	as	IN
cord-320092-0qnvydux	12	12	human	human	JJ
cord-320092-0qnvydux	12	13	galectins	galectin	NNS
cord-320092-0qnvydux	12	14	(	(	-LRB-
cord-320092-0qnvydux	12	15	galactose	galactose	NN
cord-320092-0qnvydux	12	16	-	-	HYPH
cord-320092-0qnvydux	12	17	binding	bind	VBG
cord-320092-0qnvydux	12	18	lectins	lectin	NNS
cord-320092-0qnvydux	12	19	)	)	-RRB-
cord-320092-0qnvydux	12	20	[	[	-LRB-
cord-320092-0qnvydux	12	21	97	97	CD
cord-320092-0qnvydux	12	22	]	]	-RRB-
cord-320092-0qnvydux	12	23	.	.	.
cord-320092-0qnvydux	13	1	Briefly	briefly	RB
cord-320092-0qnvydux	13	2	,	,	,
cord-320092-0qnvydux	13	3	in	in	IN
cord-320092-0qnvydux	13	4	terms	term	NNS
cord-320092-0qnvydux	13	5	of	of	IN
cord-320092-0qnvydux	13	6	the	the	DT
cord-320092-0qnvydux	13	7	putative	putative	JJ
cord-320092-0qnvydux	13	8	primary	primary	JJ
cord-320092-0qnvydux	13	9	function	function	NN
cord-320092-0qnvydux	13	10	of	of	IN
cord-320092-0qnvydux	13	11	the	the	DT
cord-320092-0qnvydux	13	12	spike	spike	NN
cord-320092-0qnvydux	13	13	protein	protein	NN
cord-320092-0qnvydux	13	14	,	,	,
cord-320092-0qnvydux	13	15	Li	Li	NNP
cord-320092-0qnvydux	13	16	comments	comment	VBZ
cord-320092-0qnvydux	13	17	that	that	IN
cord-320092-0qnvydux	13	18	"	"	``
cord-320092-0qnvydux	13	19	because	because	IN
cord-320092-0qnvydux	13	20	coronaviruses	coronaviruse	NNS
cord-320092-0qnvydux	13	21	must	must	MD
cord-320092-0qnvydux	13	22	enter	enter	VB
cord-320092-0qnvydux	13	23	cells	cell	NNS
cord-320092-0qnvydux	13	24	for	for	IN
cord-320092-0qnvydux	13	25	replication	replication	NN
cord-320092-0qnvydux	13	26	,	,	,
cord-320092-0qnvydux	13	27	membrane	membrane	NN
cord-320092-0qnvydux	13	28	fusion	fusion	NN
cord-320092-0qnvydux	13	29	is	be	VBZ
cord-320092-0qnvydux	13	30	the	the	DT
cord-320092-0qnvydux	13	31	central	central	JJ
cord-320092-0qnvydux	13	32	function	function	NN
cord-320092-0qnvydux	13	33	of	of	IN
cord-320092-0qnvydux	13	34	coronavirus	coronavirus	NN
cord-320092-0qnvydux	13	35	spikes	spike	NNS
cord-320092-0qnvydux	13	36	"	"	''
cord-320092-0qnvydux	13	37	[	[	-LRB-
cord-320092-0qnvydux	13	38	75	75	CD
cord-320092-0qnvydux	13	39	]	]	-RRB-
cord-320092-0qnvydux	13	40	.	.	.
cord-320092-0qnvydux	14	1	A	a	DT
cord-320092-0qnvydux	14	2	basic	basic	JJ
cord-320092-0qnvydux	14	3	question	question	NN
cord-320092-0qnvydux	14	4	that	that	WDT
cord-320092-0qnvydux	14	5	might	may	MD
cord-320092-0qnvydux	14	6	arise	arise	VB
cord-320092-0qnvydux	14	7	is	be	VBZ
cord-320092-0qnvydux	14	8	:	:	:
cord-320092-0qnvydux	14	9	what	what	WP
cord-320092-0qnvydux	14	10	exactly	exactly	RB
cord-320092-0qnvydux	14	11	makes	make	VBZ
cord-320092-0qnvydux	14	12	the	the	DT
cord-320092-0qnvydux	14	13	pathobiology	pathobiology	NN
cord-320092-0qnvydux	14	14	and	and	CC
cord-320092-0qnvydux	14	15	disease	disease	NN
cord-320092-0qnvydux	14	16	course	course	NN
cord-320092-0qnvydux	14	17	of	of	IN
cord-320092-0qnvydux	14	18	these	these	DT
cord-320092-0qnvydux	14	19	particular	particular	JJ
cord-320092-0qnvydux	14	20	viruses	virus	NNS
cord-320092-0qnvydux	14	21	unique	unique	JJ
cord-320092-0qnvydux	14	22	?	?	.
cord-320092-0qnvydux	15	1	And	and	CC
cord-320092-0qnvydux	15	2	,	,	,
cord-320092-0qnvydux	15	3	could	could	MD
cord-320092-0qnvydux	15	4	it	-PRON-	PRP
cord-320092-0qnvydux	15	5	be	be	VB
cord-320092-0qnvydux	15	6	that	that	IN
cord-320092-0qnvydux	15	7	,	,	,
cord-320092-0qnvydux	15	8	in	in	IN
cord-320092-0qnvydux	15	9	addition	addition	NN
cord-320092-0qnvydux	15	10	to	to	IN
cord-320092-0qnvydux	15	11	viral	viral	JJ
cord-320092-0qnvydux	15	12	replication	replication	NN
cord-320092-0qnvydux	15	13	inside	inside	IN
cord-320092-0qnvydux	15	14	the	the	DT
cord-320092-0qnvydux	15	15	particular	particular	JJ
cord-320092-0qnvydux	15	16	types	type	NNS
cord-320092-0qnvydux	15	17	of	of	IN
cord-320092-0qnvydux	15	18	human	human	JJ
cord-320092-0qnvydux	15	19	host	host	NN
cord-320092-0qnvydux	15	20	cells	cell	NNS
cord-320092-0qnvydux	15	21	,	,	,
cord-320092-0qnvydux	15	22	other	other	JJ
cord-320092-0qnvydux	15	23	intracellular	intracellular	JJ
cord-320092-0qnvydux	15	24	processes	process	NNS
cord-320092-0qnvydux	15	25	specific	specific	JJ
cord-320092-0qnvydux	15	26	to	to	IN
cord-320092-0qnvydux	15	27	these	these	DT
cord-320092-0qnvydux	15	28	viruses	virus	NNS
cord-320092-0qnvydux	15	29	are	be	VBP
cord-320092-0qnvydux	15	30	involved	involve	VBN
cord-320092-0qnvydux	15	31	?	?	.
cord-320092-0qnvydux	16	1	(	(	-LRB-
cord-320092-0qnvydux	16	2	For	for	IN
cord-320092-0qnvydux	16	3	a	a	DT
cord-320092-0qnvydux	16	4	thematically	thematically	RB
cord-320092-0qnvydux	16	5	related	related	JJ
cord-320092-0qnvydux	16	6	inquiry	inquiry	NN
cord-320092-0qnvydux	16	7	,	,	,
cord-320092-0qnvydux	16	8	see	see	VB
cord-320092-0qnvydux	16	9	e.g.	e.g.	RB
cord-320092-0qnvydux	16	10	,	,	,
cord-320092-0qnvydux	16	11	ref	ref	NN
cord-320092-0qnvydux	16	12	.	.	.
cord-320092-0qnvydux	17	1	[	[	-LRB-
cord-320092-0qnvydux	17	2	58	58	CD
cord-320092-0qnvydux	17	3	]	]	-RRB-
cord-320092-0qnvydux	17	4	.	.	.
cord-320092-0qnvydux	17	5	)	)	-RRB-
cord-320092-0qnvydux	18	1	Having	have	VBG
cord-320092-0qnvydux	18	2	this	this	DT
cord-320092-0qnvydux	18	3	in	in	IN
cord-320092-0qnvydux	18	4	mind	mind	NN
cord-320092-0qnvydux	18	5	,	,	,
cord-320092-0qnvydux	18	6	we	-PRON-	PRP
cord-320092-0qnvydux	18	7	wondered	wonder	VBD
cord-320092-0qnvydux	18	8	if	if	IN
cord-320092-0qnvydux	18	9	there	there	EX
cord-320092-0qnvydux	18	10	might	may	MD
cord-320092-0qnvydux	18	11	be	be	VB
cord-320092-0qnvydux	18	12	any	any	DT
cord-320092-0qnvydux	18	13	sequence	sequence	NN
cord-320092-0qnvydux	18	14	similarity	similarity	NN
cord-320092-0qnvydux	18	15	(	(	-LRB-
cord-320092-0qnvydux	18	16	and	and	CC
cord-320092-0qnvydux	18	17	thereby	thereby	RB
cord-320092-0qnvydux	18	18	potential	potential	JJ
cord-320092-0qnvydux	18	19	structural	structural	JJ
cord-320092-0qnvydux	18	20	similarity	similarity	NN
cord-320092-0qnvydux	18	21	)	)	-RRB-
cord-320092-0qnvydux	18	22	between	between	IN
cord-320092-0qnvydux	18	23	the	the	DT
cord-320092-0qnvydux	18	24	SARS	SARS	NNP
cord-320092-0qnvydux	18	25	-	-	HYPH
cord-320092-0qnvydux	18	26	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	18	27	spike	spike	NN
cord-320092-0qnvydux	18	28	protein	protein	NN
cord-320092-0qnvydux	18	29	(	(	-LRB-
cord-320092-0qnvydux	18	30	which	which	WDT
cord-320092-0qnvydux	18	31	has	have	VBZ
cord-320092-0qnvydux	18	32	1273	1273	CD
cord-320092-0qnvydux	18	33	amino	amino	JJ
cord-320092-0qnvydux	18	34	acids	acid	NNS
cord-320092-0qnvydux	18	35	[	[	-LRB-
cord-320092-0qnvydux	18	36	133	133	CD
cord-320092-0qnvydux	18	37	,	,	,
cord-320092-0qnvydux	18	38	134	134	CD
cord-320092-0qnvydux	18	39	]	]	-RRB-
cord-320092-0qnvydux	18	40	)	)	-RRB-
cord-320092-0qnvydux	18	41	and	and	CC
cord-320092-0qnvydux	18	42	any	any	DT
cord-320092-0qnvydux	18	43	vertebrate	vertebrate	JJ
cord-320092-0qnvydux	18	44	protein(s	protein(s	NNP
cord-320092-0qnvydux	18	45	)	)	-RRB-
cord-320092-0qnvydux	18	46	.	.	.
cord-320092-0qnvydux	19	1	A	a	DT
cord-320092-0qnvydux	19	2	simple	simple	JJ
cord-320092-0qnvydux	19	3	BLAST	blast	NN
cord-320092-0qnvydux	19	4	search	search	NN
cord-320092-0qnvydux	19	5	does	do	VBZ
cord-320092-0qnvydux	19	6	not	not	RB
cord-320092-0qnvydux	19	7	reveal	reveal	VB
cord-320092-0qnvydux	19	8	any	any	DT
cord-320092-0qnvydux	19	9	similarities	similarity	NNS
cord-320092-0qnvydux	19	10	with	with	IN
cord-320092-0qnvydux	19	11	human	human	JJ
cord-320092-0qnvydux	19	12	proteins	protein	NNS
cord-320092-0qnvydux	19	13	.	.	.
cord-320092-0qnvydux	20	1	However	however	RB
cord-320092-0qnvydux	20	2	,	,	,
cord-320092-0qnvydux	20	3	based	base	VBN
cord-320092-0qnvydux	20	4	on	on	IN
cord-320092-0qnvydux	20	5	previous	previous	JJ
cord-320092-0qnvydux	20	6	experience	experience	NN
cord-320092-0qnvydux	20	7	with	with	IN
cord-320092-0qnvydux	20	8	the	the	DT
cord-320092-0qnvydux	20	9	pufferfish	pufferfish	NN
cord-320092-0qnvydux	20	10	Takifugu	Takifugu	NNP
cord-320092-0qnvydux	20	11	rubripes	rubripes	NN
cord-320092-0qnvydux	20	12	proteome	proteome	NN
cord-320092-0qnvydux	20	13	[	[	-LRB-
cord-320092-0qnvydux	20	14	41	41	CD
cord-320092-0qnvydux	20	15	,	,	,
cord-320092-0qnvydux	20	16	42	42	CD
cord-320092-0qnvydux	20	17	,	,	,
cord-320092-0qnvydux	20	18	111	111	CD
cord-320092-0qnvydux	20	19	]	]	-RRB-
cord-320092-0qnvydux	20	20	and	and	CC
cord-320092-0qnvydux	20	21	its	-PRON-	PRP$
cord-320092-0qnvydux	20	22	unique	unique	JJ
cord-320092-0qnvydux	20	23	evolutionary	evolutionary	JJ
cord-320092-0qnvydux	20	24	history	history	NN
cord-320092-0qnvydux	20	25	,	,	,
cord-320092-0qnvydux	20	26	we	-PRON-	PRP
cord-320092-0qnvydux	20	27	initially	initially	RB
cord-320092-0qnvydux	20	28	restricted	restrict	VBD
cord-320092-0qnvydux	20	29	the	the	DT
cord-320092-0qnvydux	20	30	search	search	NN
cord-320092-0qnvydux	20	31	to	to	IN
cord-320092-0qnvydux	20	32	this	this	DT
cord-320092-0qnvydux	20	33	species	specie	NNS
cord-320092-0qnvydux	20	34	.	.	.
cord-320092-0qnvydux	21	1	Briefly	briefly	RB
cord-320092-0qnvydux	21	2	,	,	,
cord-320092-0qnvydux	21	3	teleost	teleost	NN
cord-320092-0qnvydux	21	4	ancestor	ancestor	NN
cord-320092-0qnvydux	21	5	species	specie	NNS
cord-320092-0qnvydux	21	6	underwent	undergo	VBD
cord-320092-0qnvydux	21	7	an	an	DT
cord-320092-0qnvydux	21	8	ancient	ancient	JJ
cord-320092-0qnvydux	21	9	wholegenome	wholegenome	NN
cord-320092-0qnvydux	21	10	duplication	duplication	NN
cord-320092-0qnvydux	21	11	event	event	NN
cord-320092-0qnvydux	21	12	[	[	-LRB-
cord-320092-0qnvydux	21	13	125	125	CD
cord-320092-0qnvydux	21	14	]	]	-RRB-
cord-320092-0qnvydux	21	15	,	,	,
cord-320092-0qnvydux	21	16	and	and	CC
cord-320092-0qnvydux	21	17	teleost	teleost	NN
cord-320092-0qnvydux	21	18	species	specie	NNS
cord-320092-0qnvydux	21	19	with	with	IN
cord-320092-0qnvydux	21	20	well	well	RB
cord-320092-0qnvydux	21	21	-	-	HYPH
cord-320092-0qnvydux	21	22	annotated	annotate	VBN
cord-320092-0qnvydux	21	23	genomes	genome	NNS
cord-320092-0qnvydux	21	24	such	such	JJ
cord-320092-0qnvydux	21	25	as	as	IN
cord-320092-0qnvydux	21	26	the	the	DT
cord-320092-0qnvydux	21	27	pufferfish	pufferfish	NN
cord-320092-0qnvydux	21	28	can	can	MD
cord-320092-0qnvydux	21	29	provide	provide	VB
cord-320092-0qnvydux	21	30	invaluable	invaluable	JJ
cord-320092-0qnvydux	21	31	insights	insight	NNS
cord-320092-0qnvydux	21	32	into	into	IN
cord-320092-0qnvydux	21	33	the	the	DT
cord-320092-0qnvydux	21	34	sequence	sequence	NN
cord-320092-0qnvydux	21	35	evolution	evolution	NN
cord-320092-0qnvydux	21	36	of	of	IN
cord-320092-0qnvydux	21	37	genes	gene	NNS
cord-320092-0qnvydux	21	38	with	with	IN
cord-320092-0qnvydux	21	39	a	a	DT
cord-320092-0qnvydux	21	40	clear	clear	JJ
cord-320092-0qnvydux	21	41	phylogenetic	phylogenetic	JJ
cord-320092-0qnvydux	21	42	linkage	linkage	NN
cord-320092-0qnvydux	21	43	to	to	IN
cord-320092-0qnvydux	21	44	mammalian	mammalian	JJ
cord-320092-0qnvydux	21	45	genes	gene	NNS
cord-320092-0qnvydux	21	46	(	(	-LRB-
cord-320092-0qnvydux	21	47	for	for	IN
cord-320092-0qnvydux	21	48	a	a	DT
cord-320092-0qnvydux	21	49	related	relate	VBN
cord-320092-0qnvydux	21	50	commentary	commentary	NN
cord-320092-0qnvydux	21	51	,	,	,
cord-320092-0qnvydux	21	52	see	see	VB
cord-320092-0qnvydux	21	53	ref	ref	NN
cord-320092-0qnvydux	21	54	.	.	.
cord-320092-0qnvydux	22	1	[	[	-LRB-
cord-320092-0qnvydux	22	2	76	76	CD
cord-320092-0qnvydux	22	3	]	]	-RRB-
cord-320092-0qnvydux	22	4	)	)	-RRB-
cord-320092-0qnvydux	22	5	.	.	.
cord-320092-0qnvydux	23	1	Interestingly	interestingly	RB
cord-320092-0qnvydux	23	2	,	,	,
cord-320092-0qnvydux	23	3	a	a	DT
cord-320092-0qnvydux	23	4	query	query	NN
cord-320092-0qnvydux	23	5	using	use	VBG
cord-320092-0qnvydux	23	6	the	the	DT
cord-320092-0qnvydux	23	7	full	full	JJ
cord-320092-0qnvydux	23	8	-	-	HYPH
cord-320092-0qnvydux	23	9	length	length	NN
cord-320092-0qnvydux	23	10	SARS	SARS	NNP
cord-320092-0qnvydux	23	11	-	-	HYPH
cord-320092-0qnvydux	23	12	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	23	13	spike	spike	NN
cord-320092-0qnvydux	23	14	protein	protein	NN
cord-320092-0qnvydux	23	15	(	(	-LRB-
cord-320092-0qnvydux	23	16	accession	accession	NN
cord-320092-0qnvydux	23	17	no	no	UH
cord-320092-0qnvydux	23	18	.	.	.
cord-320092-0qnvydux	23	19	YP_009724390.1	YP_009724390.1	NNP
cord-320092-0qnvydux	23	20	)	)	-RRB-
cord-320092-0qnvydux	23	21	revealed	reveal	VBD
cord-320092-0qnvydux	23	22	a	a	DT
cord-320092-0qnvydux	23	23	sole	sole	JJ
cord-320092-0qnvydux	23	24	hit	hit	VBN
cord-320092-0qnvydux	23	25	with	with	IN
cord-320092-0qnvydux	23	26	the	the	DT
cord-320092-0qnvydux	23	27	pufferfish	pufferfish	NN
cord-320092-0qnvydux	23	28	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	23	29	protein	protein	NN
cord-320092-0qnvydux	23	30	(	(	-LRB-
cord-320092-0qnvydux	23	31	XP	XP	NNP
cord-320092-0qnvydux	23	32	_	_	NNP
cord-320092-0qnvydux	24	1	003965681.1	003965681.1	LS
cord-320092-0qnvydux	24	2	;	;	:
cord-320092-0qnvydux	24	3	score	score	VB
cord-320092-0qnvydux	24	4	:	:	:
cord-320092-0qnvydux	24	5	32.7	32.7	CD
cord-320092-0qnvydux	24	6	,	,	,
cord-320092-0qnvydux	24	7	E	e	NN
cord-320092-0qnvydux	24	8	-	-	NN
cord-320092-0qnvydux	24	9	value	value	NN
cord-320092-0qnvydux	24	10	:	:	:
cord-320092-0qnvydux	24	11	0.54	0.54	CD
cord-320092-0qnvydux	24	12	)	)	-RRB-
cord-320092-0qnvydux	24	13	.	.	.
cord-320092-0qnvydux	25	1	Given	give	VBN
cord-320092-0qnvydux	25	2	that	that	IN
cord-320092-0qnvydux	25	3	SARS	SARS	NNP
cord-320092-0qnvydux	25	4	-	-	HYPH
cord-320092-0qnvydux	25	5	like	like	JJ
cord-320092-0qnvydux	25	6	coronaviruses	coronaviruse	NNS
cord-320092-0qnvydux	25	7	can	can	MD
cord-320092-0qnvydux	25	8	be	be	VB
cord-320092-0qnvydux	25	9	found	find	VBN
cord-320092-0qnvydux	25	10	in	in	IN
cord-320092-0qnvydux	25	11	bats	bat	NNS
cord-320092-0qnvydux	25	12	[	[	-LRB-
cord-320092-0qnvydux	25	13	133	133	CD
cord-320092-0qnvydux	25	14	,	,	,
cord-320092-0qnvydux	25	15	134	134	CD
cord-320092-0qnvydux	25	16	]	]	-RRB-
cord-320092-0qnvydux	25	17	,	,	,
cord-320092-0qnvydux	25	18	we	-PRON-	PRP
cord-320092-0qnvydux	25	19	also	also	RB
cord-320092-0qnvydux	25	20	used	use	VBD
cord-320092-0qnvydux	25	21	a	a	DT
cord-320092-0qnvydux	25	22	full	full	JJ
cord-320092-0qnvydux	25	23	-	-	HYPH
cord-320092-0qnvydux	25	24	length	length	NN
cord-320092-0qnvydux	25	25	bat	bat	NN
cord-320092-0qnvydux	25	26	coronavirus	coronavirus	NN
cord-320092-0qnvydux	25	27	sequence	sequence	NN
cord-320092-0qnvydux	25	28	(	(	-LRB-
cord-320092-0qnvydux	25	29	ANA96027.1	ANA96027.1	NNP
cord-320092-0qnvydux	25	30	)	)	-RRB-
cord-320092-0qnvydux	25	31	as	as	IN
cord-320092-0qnvydux	25	32	the	the	DT
cord-320092-0qnvydux	25	33	query	query	NN
cord-320092-0qnvydux	25	34	,	,	,
cord-320092-0qnvydux	25	35	which	which	WDT
cord-320092-0qnvydux	25	36	showed	show	VBD
cord-320092-0qnvydux	25	37	a	a	DT
cord-320092-0qnvydux	25	38	closer	close	JJR
cord-320092-0qnvydux	25	39	match	match	NN
cord-320092-0qnvydux	25	40	with	with	IN
cord-320092-0qnvydux	25	41	pufferfish	pufferfish	NN
cord-320092-0qnvydux	25	42	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	25	43	(	(	-LRB-
cord-320092-0qnvydux	25	44	score	score	NN
cord-320092-0qnvydux	25	45	:	:	:
cord-320092-0qnvydux	25	46	38.5	38.5	CD
cord-320092-0qnvydux	25	47	,	,	,
cord-320092-0qnvydux	25	48	E	e	NN
cord-320092-0qnvydux	25	49	-	-	NN
cord-320092-0qnvydux	25	50	value	value	NN
cord-320092-0qnvydux	25	51	:	:	:
cord-320092-0qnvydux	25	52	0.005	0.005	CD
cord-320092-0qnvydux	25	53	)	)	-RRB-
cord-320092-0qnvydux	25	54	.	.	.
cord-320092-0qnvydux	26	1	Conversely	conversely	RB
cord-320092-0qnvydux	26	2	,	,	,
cord-320092-0qnvydux	26	3	a	a	DT
cord-320092-0qnvydux	26	4	BLAST	blast	NN
cord-320092-0qnvydux	26	5	search	search	NN
cord-320092-0qnvydux	26	6	in	in	IN
cord-320092-0qnvydux	26	7	the	the	DT
cord-320092-0qnvydux	26	8	Coronaviridae	Coronaviridae	NNP
cord-320092-0qnvydux	26	9	family	family	NN
cord-320092-0qnvydux	26	10	of	of	IN
cord-320092-0qnvydux	26	11	viruses	virus	NNS
cord-320092-0qnvydux	26	12	using	use	VBG
cord-320092-0qnvydux	26	13	the	the	DT
cord-320092-0qnvydux	26	14	pufferfish	pufferfish	NN
cord-320092-0qnvydux	26	15	hepcidin	hepcidin	NN
cord-320092-0qnvydux	26	16	(	(	-LRB-
cord-320092-0qnvydux	26	17	XP	XP	NNP
cord-320092-0qnvydux	26	18	_	_	NNP
cord-320092-0qnvydux	26	19	003965681.1	003965681.1	CD
cord-320092-0qnvydux	26	20	)	)	-RRB-
cord-320092-0qnvydux	26	21	revealed	reveal	VBD
cord-320092-0qnvydux	26	22	the	the	DT
cord-320092-0qnvydux	26	23	bat	bat	NN
cord-320092-0qnvydux	26	24	coronavirus	coronavirus	NN
cord-320092-0qnvydux	26	25	spike	spike	NN
cord-320092-0qnvydux	26	26	protein	protein	NN
cord-320092-0qnvydux	26	27	(	(	-LRB-
cord-320092-0qnvydux	26	28	ANA96027.1	ANA96027.1	NNP
cord-320092-0qnvydux	26	29	)	)	-RRB-
cord-320092-0qnvydux	26	30	as	as	IN
cord-320092-0qnvydux	26	31	the	the	DT
cord-320092-0qnvydux	26	32	top	top	JJ
cord-320092-0qnvydux	26	33	hit	hit	NN
cord-320092-0qnvydux	26	34	(	(	-LRB-
cord-320092-0qnvydux	26	35	score	score	NN
cord-320092-0qnvydux	26	36	:	:	:
cord-320092-0qnvydux	26	37	38.5	38.5	CD
cord-320092-0qnvydux	26	38	,	,	,
cord-320092-0qnvydux	26	39	E	e	NN
cord-320092-0qnvydux	26	40	-	-	NN
cord-320092-0qnvydux	26	41	value	value	NN
cord-320092-0qnvydux	26	42	:	:	:
cord-320092-0qnvydux	26	43	5e-04	5e-04	ADD
cord-320092-0qnvydux	26	44	)	)	-RRB-
cord-320092-0qnvydux	26	45	.	.	.
cord-320092-0qnvydux	27	1	The	the	DT
cord-320092-0qnvydux	27	2	scores	score	NNS
cord-320092-0qnvydux	27	3	and	and	CC
cord-320092-0qnvydux	27	4	E	E	NNS
cord-320092-0qnvydux	27	5	-	-	NNS
cord-320092-0qnvydux	27	6	values	value	NNS
cord-320092-0qnvydux	27	7	here	here	RB
cord-320092-0qnvydux	27	8	are	be	VBP
cord-320092-0qnvydux	27	9	not	not	RB
cord-320092-0qnvydux	27	10	meant	mean	VBN
cord-320092-0qnvydux	27	11	to	to	TO
cord-320092-0qnvydux	27	12	indicate	indicate	VB
cord-320092-0qnvydux	27	13	any	any	DT
cord-320092-0qnvydux	27	14	claims	claim	NNS
cord-320092-0qnvydux	27	15	of	of	IN
cord-320092-0qnvydux	27	16	statistical	statistical	JJ
cord-320092-0qnvydux	27	17	significance	significance	NN
cord-320092-0qnvydux	27	18	but	but	CC
cord-320092-0qnvydux	27	19	are	be	VBP
cord-320092-0qnvydux	27	20	rather	rather	RB
cord-320092-0qnvydux	27	21	provided	provide	VBN
cord-320092-0qnvydux	27	22	for	for	IN
cord-320092-0qnvydux	27	23	the	the	DT
cord-320092-0qnvydux	27	24	purpose	purpose	NN
cord-320092-0qnvydux	27	25	of	of	IN
cord-320092-0qnvydux	27	26	comparison	comparison	NN
cord-320092-0qnvydux	27	27	.	.	.
cord-320092-0qnvydux	28	1	This	this	DT
cord-320092-0qnvydux	28	2	similarity	similarity	NN
cord-320092-0qnvydux	28	3	between	between	IN
cord-320092-0qnvydux	28	4	the	the	DT
cord-320092-0qnvydux	28	5	spike	spike	NN
cord-320092-0qnvydux	28	6	protein	protein	NN
cord-320092-0qnvydux	28	7	and	and	CC
cord-320092-0qnvydux	28	8	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	28	9	is	be	VBZ
cord-320092-0qnvydux	28	10	at	at	IN
cord-320092-0qnvydux	28	11	the	the	DT
cord-320092-0qnvydux	28	12	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	28	13	tail	tail	NN
cord-320092-0qnvydux	28	14	[	[	-LRB-
cord-320092-0qnvydux	28	15	80	80	CD
cord-320092-0qnvydux	28	16	]	]	-RRB-
cord-320092-0qnvydux	28	17	of	of	IN
cord-320092-0qnvydux	28	18	the	the	DT
cord-320092-0qnvydux	28	19	spike	spike	NN
cord-320092-0qnvydux	28	20	protein	protein	NN
cord-320092-0qnvydux	28	21	,	,	,
cord-320092-0qnvydux	28	22	or	or	CC
cord-320092-0qnvydux	28	23	,	,	,
cord-320092-0qnvydux	28	24	depending	depend	VBG
cord-320092-0qnvydux	28	25	on	on	IN
cord-320092-0qnvydux	28	26	the	the	DT
cord-320092-0qnvydux	28	27	exact	exact	JJ
cord-320092-0qnvydux	28	28	domain	domain	NN
cord-320092-0qnvydux	28	29	delineation	delineation	NN
cord-320092-0qnvydux	28	30	,	,	,
cord-320092-0qnvydux	28	31	perhaps	perhaps	RB
cord-320092-0qnvydux	28	32	at	at	IN
cord-320092-0qnvydux	28	33	the	the	DT
cord-320092-0qnvydux	28	34	junction	junction	NN
cord-320092-0qnvydux	28	35	between	between	IN
cord-320092-0qnvydux	28	36	the	the	DT
cord-320092-0qnvydux	28	37	TM	TM	NNP
cord-320092-0qnvydux	28	38	and	and	CC
cord-320092-0qnvydux	28	39	CT	CT	NNP
cord-320092-0qnvydux	28	40	domains	domain	NNS
cord-320092-0qnvydux	28	41	.	.	.
cord-320092-0qnvydux	29	1	A	a	DT
cord-320092-0qnvydux	29	2	multiple	multiple	JJ
cord-320092-0qnvydux	29	3	sequence	sequence	NN
cord-320092-0qnvydux	29	4	alignment	alignment	NN
cord-320092-0qnvydux	29	5	of	of	IN
cord-320092-0qnvydux	29	6	this	this	DT
cord-320092-0qnvydux	29	7	sequence	sequence	NN
cord-320092-0qnvydux	29	8	region	region	NN
cord-320092-0qnvydux	29	9	(	(	-LRB-
cord-320092-0qnvydux	29	10	generated	generate	VBN
cord-320092-0qnvydux	29	11	using	use	VBG
cord-320092-0qnvydux	29	12	the	the	DT
cord-320092-0qnvydux	29	13	AlignX	AlignX	NNPS
cord-320092-0qnvydux	29	14	feature	feature	NN
cord-320092-0qnvydux	29	15	of	of	IN
cord-320092-0qnvydux	29	16	Vector	Vector	NNP
cord-320092-0qnvydux	29	17	NTI	NTI	NNP
cord-320092-0qnvydux	29	18	Advance	Advance	NNP
cord-320092-0qnvydux	29	19	11.0	11.0	CD
cord-320092-0qnvydux	29	20	,	,	,
cord-320092-0qnvydux	29	21	Invitrogen	Invitrogen	NNP
cord-320092-0qnvydux	29	22	,	,	,
cord-320092-0qnvydux	29	23	Carlsbad	Carlsbad	NNP
cord-320092-0qnvydux	29	24	,	,	,
cord-320092-0qnvydux	29	25	CA	CA	NNP
cord-320092-0qnvydux	29	26	,	,	,
cord-320092-0qnvydux	29	27	USA	USA	NNP
cord-320092-0qnvydux	29	28	)	)	-RRB-
cord-320092-0qnvydux	29	29	,	,	,
cord-320092-0qnvydux	29	30	using	use	VBG
cord-320092-0qnvydux	29	31	three	three	CD
cord-320092-0qnvydux	29	32	coronavirus	coronavirus	NN
cord-320092-0qnvydux	29	33	spike	spike	NN
cord-320092-0qnvydux	29	34	proteins	protein	NNS
cord-320092-0qnvydux	29	35	and	and	CC
cord-320092-0qnvydux	29	36	four	four	CD
cord-320092-0qnvydux	29	37	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	29	38	proteins	protein	NNS
cord-320092-0qnvydux	29	39	(	(	-LRB-
cord-320092-0qnvydux	29	40	from	from	IN
cord-320092-0qnvydux	29	41	pufferfish	pufferfish	NN
cord-320092-0qnvydux	29	42	,	,	,
cord-320092-0qnvydux	29	43	bat	bat	NN
cord-320092-0qnvydux	29	44	and	and	CC
cord-320092-0qnvydux	29	45	human	human	NN
cord-320092-0qnvydux	29	46	)	)	-RRB-
cord-320092-0qnvydux	29	47	is	be	VBZ
cord-320092-0qnvydux	29	48	illustrated	illustrate	VBN
cord-320092-0qnvydux	29	49	in	in	IN
cord-320092-0qnvydux	29	50	Fig	Fig	NNP
cord-320092-0qnvydux	29	51	.	.	.
cord-320092-0qnvydux	29	52	1a	1a	CD
cord-320092-0qnvydux	29	53	.	.	.
cord-320092-0qnvydux	30	1	The	the	DT
cord-320092-0qnvydux	30	2	alignment	alignment	NN
cord-320092-0qnvydux	30	3	depicts	depict	VBZ
cord-320092-0qnvydux	30	4	a	a	DT
cord-320092-0qnvydux	30	5	number	number	NN
cord-320092-0qnvydux	30	6	of	of	IN
cord-320092-0qnvydux	30	7	conserved	conserved	JJ
cord-320092-0qnvydux	30	8	motifs	motif	NNS
cord-320092-0qnvydux	30	9	,	,	,
cord-320092-0qnvydux	30	10	particularly	particularly	RB
cord-320092-0qnvydux	30	11	between	between	IN
cord-320092-0qnvydux	30	12	the	the	DT
cord-320092-0qnvydux	30	13	first	first	JJ
cord-320092-0qnvydux	30	14	pufferfish	pufferfish	NN
cord-320092-0qnvydux	30	15	hepcidin	hepcidin	NN
cord-320092-0qnvydux	30	16	sequence	sequence	NN
cord-320092-0qnvydux	30	17	(	(	-LRB-
cord-320092-0qnvydux	30	18	various	various	JJ
cord-320092-0qnvydux	30	19	pufferfish	pufferfish	NN
cord-320092-0qnvydux	30	20	species	specie	NNS
cord-320092-0qnvydux	30	21	have	have	VBP
cord-320092-0qnvydux	30	22	at	at	RB
cord-320092-0qnvydux	30	23	least	least	RBS
cord-320092-0qnvydux	30	24	two	two	CD
cord-320092-0qnvydux	30	25	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	30	26	-	-	HYPH
cord-320092-0qnvydux	30	27	like	like	JJ
cord-320092-0qnvydux	30	28	genes	gene	NNS
cord-320092-0qnvydux	30	29	[	[	-LRB-
cord-320092-0qnvydux	30	30	55	55	CD
cord-320092-0qnvydux	30	31	]	]	-RRB-
cord-320092-0qnvydux	30	32	)	)	-RRB-
cord-320092-0qnvydux	30	33	and	and	CC
cord-320092-0qnvydux	30	34	the	the	DT
cord-320092-0qnvydux	30	35	coronavirus	coronavirus	NN
cord-320092-0qnvydux	30	36	spike	spike	NN
cord-320092-0qnvydux	30	37	proteins	protein	NNS
cord-320092-0qnvydux	30	38	.	.	.
cord-320092-0qnvydux	31	1	In	in	IN
cord-320092-0qnvydux	31	2	a	a	DT
cord-320092-0qnvydux	31	3	sense	sense	NN
cord-320092-0qnvydux	31	4	,	,	,
cord-320092-0qnvydux	31	5	the	the	DT
cord-320092-0qnvydux	31	6	pufferfish	pufferfish	NN
cord-320092-0qnvydux	31	7	sequence	sequence	NN
cord-320092-0qnvydux	31	8	seems	seem	VBZ
cord-320092-0qnvydux	31	9	to	to	TO
cord-320092-0qnvydux	31	10	act	act	VB
cord-320092-0qnvydux	31	11	as	as	IN
cord-320092-0qnvydux	31	12	a	a	DT
cord-320092-0qnvydux	31	13	'	'	``
cord-320092-0qnvydux	31	14	bridge	bridge	NN
cord-320092-0qnvydux	31	15	'	'	''
cord-320092-0qnvydux	31	16	between	between	IN
cord-320092-0qnvydux	31	17	the	the	DT
cord-320092-0qnvydux	31	18	coronavirus	coronavirus	NN
cord-320092-0qnvydux	31	19	motifs	motif	NNS
cord-320092-0qnvydux	31	20	and	and	CC
cord-320092-0qnvydux	31	21	those	those	DT
cord-320092-0qnvydux	31	22	in	in	IN
cord-320092-0qnvydux	31	23	the	the	DT
cord-320092-0qnvydux	31	24	human	human	JJ
cord-320092-0qnvydux	31	25	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	31	26	sequence	sequence	NN
cord-320092-0qnvydux	31	27	.	.	.
cord-320092-0qnvydux	32	1	This	this	DT
cord-320092-0qnvydux	32	2	may	may	MD
cord-320092-0qnvydux	32	3	not	not	RB
cord-320092-0qnvydux	32	4	be	be	VB
cord-320092-0qnvydux	32	5	surprising	surprising	JJ
cord-320092-0qnvydux	32	6	particularly	particularly	RB
cord-320092-0qnvydux	32	7	given	give	VBN
cord-320092-0qnvydux	32	8	the	the	DT
cord-320092-0qnvydux	32	9	evolutionary	evolutionary	JJ
cord-320092-0qnvydux	32	10	context	context	NN
cord-320092-0qnvydux	32	11	of	of	IN
cord-320092-0qnvydux	32	12	teleost	teleost	JJ
cord-320092-0qnvydux	32	13	species	specie	NNS
cord-320092-0qnvydux	32	14	described	describe	VBN
cord-320092-0qnvydux	32	15	earlier	early	RBR
cord-320092-0qnvydux	32	16	.	.	.
cord-320092-0qnvydux	33	1	The	the	DT
cord-320092-0qnvydux	33	2	similar	similar	JJ
cord-320092-0qnvydux	33	3	cysteine	cysteine	NN
cord-320092-0qnvydux	33	4	-	-	HYPH
cord-320092-0qnvydux	33	5	rich	rich	JJ
cord-320092-0qnvydux	33	6	motif	motif	NN
cord-320092-0qnvydux	33	7	takes	take	VBZ
cord-320092-0qnvydux	33	8	the	the	DT
cord-320092-0qnvydux	33	9	following	follow	VBG
cord-320092-0qnvydux	33	10	form	form	NN
cord-320092-0qnvydux	33	11	:	:	:
cord-320092-0qnvydux	33	12	'	'	''
cord-320092-0qnvydux	33	13	LXXXTXCCXCCKGXXXCGXCC(R	lxxxtxccxcckgxxxcgxcc(r	NN
cord-320092-0qnvydux	33	14	/	/	SYM
cord-320092-0qnvydux	33	15	K)F	k)f	NN
cord-320092-0qnvydux	33	16	'	'	''
cord-320092-0qnvydux	33	17	.	.	.
cord-320092-0qnvydux	34	1	Of	of	IN
cord-320092-0qnvydux	34	2	note	note	NN
cord-320092-0qnvydux	34	3	,	,	,
cord-320092-0qnvydux	34	4	the	the	DT
cord-320092-0qnvydux	34	5	eight	eight	CD
cord-320092-0qnvydux	34	6	cysteines	cysteine	NNS
cord-320092-0qnvydux	34	7	of	of	IN
cord-320092-0qnvydux	34	8	the	the	DT
cord-320092-0qnvydux	34	9	mature	mature	JJ
cord-320092-0qnvydux	34	10	human	human	JJ
cord-320092-0qnvydux	34	11	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	34	12	in	in	IN
cord-320092-0qnvydux	34	13	the	the	DT
cord-320092-0qnvydux	34	14	similarity	similarity	NN
cord-320092-0qnvydux	34	15	motif	motif	NN
cord-320092-0qnvydux	34	16	,	,	,
cord-320092-0qnvydux	34	17	and	and	CC
cord-320092-0qnvydux	34	18	the	the	DT
cord-320092-0qnvydux	34	19	aligned	aligned	JJ
cord-320092-0qnvydux	34	20	cysteines	cysteine	NNS
cord-320092-0qnvydux	34	21	of	of	IN
cord-320092-0qnvydux	34	22	the	the	DT
cord-320092-0qnvydux	34	23	SARS	SARS	NNP
cord-320092-0qnvydux	34	24	-	-	HYPH
cord-320092-0qnvydux	34	25	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	34	26	spike	spike	NN
cord-320092-0qnvydux	34	27	protein	protein	NN
cord-320092-0qnvydux	34	28	,	,	,
cord-320092-0qnvydux	34	29	are	be	VBP
cord-320092-0qnvydux	34	30	not	not	RB
cord-320092-0qnvydux	34	31	all	all	DT
cord-320092-0qnvydux	34	32	specifically	specifically	RB
cord-320092-0qnvydux	34	33	coded	code	VBN
cord-320092-0qnvydux	34	34	by	by	IN
cord-320092-0qnvydux	34	35	one	one	CD
cord-320092-0qnvydux	34	36	of	of	IN
cord-320092-0qnvydux	34	37	the	the	DT
cord-320092-0qnvydux	34	38	two	two	CD
cord-320092-0qnvydux	34	39	cysteine	cysteine	NN
cord-320092-0qnvydux	34	40	-	-	HYPH
cord-320092-0qnvydux	34	41	coding	code	VBG
cord-320092-0qnvydux	34	42	codons	codon	NNS
cord-320092-0qnvydux	34	43	(	(	-LRB-
cord-320092-0qnvydux	34	44	TGC	TGC	NNP
cord-320092-0qnvydux	34	45	and	and	CC
cord-320092-0qnvydux	34	46	TGT	TGT	NNP
cord-320092-0qnvydux	34	47	)	)	-RRB-
cord-320092-0qnvydux	34	48	.	.	.
cord-320092-0qnvydux	35	1	Both	both	DT
cord-320092-0qnvydux	35	2	codons	codon	NNS
cord-320092-0qnvydux	35	3	are	be	VBP
cord-320092-0qnvydux	35	4	present	present	JJ
cord-320092-0qnvydux	35	5	in	in	IN
cord-320092-0qnvydux	35	6	the	the	DT
cord-320092-0qnvydux	35	7	respective	respective	JJ
cord-320092-0qnvydux	35	8	gene	gene	NN
cord-320092-0qnvydux	35	9	segments	segment	NNS
cord-320092-0qnvydux	35	10	.	.	.
cord-320092-0qnvydux	36	1	Also	also	RB
cord-320092-0qnvydux	36	2	,	,	,
cord-320092-0qnvydux	36	3	for	for	IN
cord-320092-0qnvydux	36	4	comparison	comparison	NN
cord-320092-0qnvydux	36	5	purposes	purpose	NNS
cord-320092-0qnvydux	36	6	,	,	,
cord-320092-0qnvydux	36	7	as	as	IN
cord-320092-0qnvydux	36	8	the	the	DT
cord-320092-0qnvydux	36	9	coronavirus	coronavirus	NN
cord-320092-0qnvydux	36	10	envelope	envelope	NN
cord-320092-0qnvydux	36	11	protein	protein	NN
cord-320092-0qnvydux	36	12	[	[	-LRB-
cord-320092-0qnvydux	36	13	112	112	CD
cord-320092-0qnvydux	36	14	]	]	-RRB-
cord-320092-0qnvydux	36	15	contains	contain	VBZ
cord-320092-0qnvydux	36	16	a	a	DT
cord-320092-0qnvydux	36	17	related	related	JJ
cord-320092-0qnvydux	36	18	'	'	``
cord-320092-0qnvydux	36	19	LCAYCCN	LCAYCCN	NNP
cord-320092-0qnvydux	36	20	'	'	''
cord-320092-0qnvydux	36	21	motif	motif	NN
cord-320092-0qnvydux	36	22	[	[	-LRB-
cord-320092-0qnvydux	36	23	135	135	CD
cord-320092-0qnvydux	36	24	]	]	-RRB-
cord-320092-0qnvydux	36	25	,	,	,
cord-320092-0qnvydux	36	26	this	this	DT
cord-320092-0qnvydux	36	27	sequence	sequence	NN
cord-320092-0qnvydux	36	28	was	be	VBD
cord-320092-0qnvydux	36	29	added	add	VBN
cord-320092-0qnvydux	36	30	as	as	IN
cord-320092-0qnvydux	36	31	the	the	DT
cord-320092-0qnvydux	36	32	last	last	JJ
cord-320092-0qnvydux	36	33	line	line	NN
cord-320092-0qnvydux	36	34	of	of	IN
cord-320092-0qnvydux	36	35	the	the	DT
cord-320092-0qnvydux	36	36	alignment	alignment	NN
cord-320092-0qnvydux	36	37	.	.	.
cord-320092-0qnvydux	37	1	Although	although	IN
cord-320092-0qnvydux	37	2	this	this	DT
cord-320092-0qnvydux	37	3	is	be	VBZ
cord-320092-0qnvydux	37	4	a	a	DT
cord-320092-0qnvydux	37	5	'	'	``
cord-320092-0qnvydux	37	6	distant	distant	JJ
cord-320092-0qnvydux	37	7	'	'	''
cord-320092-0qnvydux	37	8	and	and	CC
cord-320092-0qnvydux	37	9	limited	limited	JJ
cord-320092-0qnvydux	37	10	sequence	sequence	NN
cord-320092-0qnvydux	37	11	similarity	similarity	NN
cord-320092-0qnvydux	37	12	,	,	,
cord-320092-0qnvydux	37	13	it	-PRON-	PRP
cord-320092-0qnvydux	37	14	can	can	MD
cord-320092-0qnvydux	37	15	not	not	RB
cord-320092-0qnvydux	37	16	be	be	VB
cord-320092-0qnvydux	37	17	attributed	attribute	VBN
cord-320092-0qnvydux	37	18	to	to	IN
cord-320092-0qnvydux	37	19	'	'	``
cord-320092-0qnvydux	37	20	chance	chance	NN
cord-320092-0qnvydux	37	21	'	'	''
cord-320092-0qnvydux	37	22	.	.	.
cord-320092-0qnvydux	38	1	The	the	DT
cord-320092-0qnvydux	38	2	search	search	NN
cord-320092-0qnvydux	38	3	that	that	WDT
cord-320092-0qnvydux	38	4	found	find	VBD
cord-320092-0qnvydux	38	5	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	38	6	did	do	VBD
cord-320092-0qnvydux	38	7	not	not	RB
cord-320092-0qnvydux	38	8	reveal	reveal	VB
cord-320092-0qnvydux	38	9	a	a	DT
cord-320092-0qnvydux	38	10	range	range	NN
cord-320092-0qnvydux	38	11	of	of	IN
cord-320092-0qnvydux	38	12	similarities	similarity	NNS
cord-320092-0qnvydux	38	13	with	with	IN
cord-320092-0qnvydux	38	14	other	other	JJ
cord-320092-0qnvydux	38	15	teleost	teleost	NN
cord-320092-0qnvydux	38	16	proteins	protein	NNS
cord-320092-0qnvydux	38	17	.	.	.
cord-320092-0qnvydux	39	1	Moreover	moreover	RB
cord-320092-0qnvydux	39	2	,	,	,
cord-320092-0qnvydux	39	3	there	there	EX
cord-320092-0qnvydux	39	4	are	be	VBP
cord-320092-0qnvydux	39	5	many	many	JJ
cord-320092-0qnvydux	39	6	cysteine	cysteine	JJ
cord-320092-0qnvydux	39	7	-	-	HYPH
cord-320092-0qnvydux	39	8	rich	rich	JJ
cord-320092-0qnvydux	39	9	protein	protein	NN
cord-320092-0qnvydux	39	10	sequences	sequence	NNS
cord-320092-0qnvydux	39	11	in	in	IN
cord-320092-0qnvydux	39	12	teleosts	teleost	NNS
cord-320092-0qnvydux	39	13	and	and	CC
cord-320092-0qnvydux	39	14	vertebrates	vertebrate	NNS
cord-320092-0qnvydux	39	15	in	in	IN
cord-320092-0qnvydux	39	16	general	general	JJ
cord-320092-0qnvydux	39	17	,	,	,
cord-320092-0qnvydux	39	18	yet	yet	CC
cord-320092-0qnvydux	39	19	this	this	DT
cord-320092-0qnvydux	39	20	similarity	similarity	NN
cord-320092-0qnvydux	39	21	to	to	IN
cord-320092-0qnvydux	39	22	the	the	DT
cord-320092-0qnvydux	39	23	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	39	24	gene	gene	NN
cord-320092-0qnvydux	39	25	family	family	NN
cord-320092-0qnvydux	39	26	(	(	-LRB-
cord-320092-0qnvydux	39	27	not	not	RB
cord-320092-0qnvydux	39	28	merely	merely	RB
cord-320092-0qnvydux	39	29	a	a	DT
cord-320092-0qnvydux	39	30	one	one	CD
cord-320092-0qnvydux	39	31	-	-	HYPH
cord-320092-0qnvydux	39	32	off	off	RP
cord-320092-0qnvydux	39	33	sequence	sequence	NN
cord-320092-0qnvydux	39	34	)	)	-RRB-
cord-320092-0qnvydux	39	35	was	be	VBD
cord-320092-0qnvydux	39	36	unique	unique	JJ
cord-320092-0qnvydux	39	37	and	and	CC
cord-320092-0qnvydux	39	38	specific	specific	JJ
cord-320092-0qnvydux	39	39	.	.	.
cord-320092-0qnvydux	40	1	How	how	WRB
cord-320092-0qnvydux	40	2	or	or	CC
cord-320092-0qnvydux	40	3	why	why	WRB
cord-320092-0qnvydux	40	4	this	this	DT
cord-320092-0qnvydux	40	5	similarity	similarity	NN
cord-320092-0qnvydux	40	6	arose	arise	VBD
cord-320092-0qnvydux	40	7	is	be	VBZ
cord-320092-0qnvydux	40	8	then	then	RB
cord-320092-0qnvydux	40	9	a	a	DT
cord-320092-0qnvydux	40	10	separate	separate	JJ
cord-320092-0qnvydux	40	11	,	,	,
cord-320092-0qnvydux	40	12	and	and	CC
cord-320092-0qnvydux	40	13	potential	potential	JJ
cord-320092-0qnvydux	40	14	follow	follow	NN
cord-320092-0qnvydux	40	15	-	-	HYPH
cord-320092-0qnvydux	40	16	up	up	NN
cord-320092-0qnvydux	40	17	,	,	,
cord-320092-0qnvydux	40	18	question	question	NN
cord-320092-0qnvydux	40	19	.	.	.
cord-320092-0qnvydux	41	1	On	on	IN
cord-320092-0qnvydux	41	2	this	this	DT
cord-320092-0qnvydux	41	3	point	point	NN
cord-320092-0qnvydux	41	4	,	,	,
cord-320092-0qnvydux	41	5	rather	rather	RB
cord-320092-0qnvydux	41	6	than	than	IN
cord-320092-0qnvydux	41	7	framing	frame	VBG
cord-320092-0qnvydux	41	8	the	the	DT
cord-320092-0qnvydux	41	9	question	question	NN
cord-320092-0qnvydux	41	10	as	as	IN
cord-320092-0qnvydux	41	11	one	one	CD
cord-320092-0qnvydux	41	12	having	have	VBG
cord-320092-0qnvydux	41	13	to	to	TO
cord-320092-0qnvydux	41	14	do	do	VB
cord-320092-0qnvydux	41	15	with	with	IN
cord-320092-0qnvydux	41	16	a	a	DT
cord-320092-0qnvydux	41	17	chance	chance	NN
cord-320092-0qnvydux	41	18	/	/	SYM
cord-320092-0qnvydux	41	19	random	random	JJ
cord-320092-0qnvydux	41	20	occurrence	occurrence	NN
cord-320092-0qnvydux	41	21	,	,	,
cord-320092-0qnvydux	41	22	it	-PRON-	PRP
cord-320092-0qnvydux	41	23	could	could	MD
cord-320092-0qnvydux	41	24	more	more	RBR
cord-320092-0qnvydux	41	25	aptly	aptly	RB
cord-320092-0qnvydux	41	26	be	be	VB
cord-320092-0qnvydux	41	27	framed	frame	VBN
cord-320092-0qnvydux	41	28	under	under	IN
cord-320092-0qnvydux	41	29	concepts	concept	NNS
cord-320092-0qnvydux	41	30	related	relate	VBN
cord-320092-0qnvydux	41	31	to	to	IN
cord-320092-0qnvydux	41	32	convergent	convergent	JJ
cord-320092-0qnvydux	41	33	/	/	SYM
cord-320092-0qnvydux	41	34	adaptive	adaptive	JJ
cord-320092-0qnvydux	41	35	evolution	evolution	NN
cord-320092-0qnvydux	41	36	versus	versus	IN
cord-320092-0qnvydux	41	37	common	common	JJ
cord-320092-0qnvydux	41	38	ancestry	ancestry	NN
cord-320092-0qnvydux	41	39	.	.	.
cord-320092-0qnvydux	42	1	Clearly	clearly	RB
cord-320092-0qnvydux	42	2	,	,	,
cord-320092-0qnvydux	42	3	however	however	RB
cord-320092-0qnvydux	42	4	,	,	,
cord-320092-0qnvydux	42	5	no	no	DT
cord-320092-0qnvydux	42	6	conclusive	conclusive	JJ
cord-320092-0qnvydux	42	7	claims	claim	VBZ
cord-320092-0qnvydux	42	8	about	about	IN
cord-320092-0qnvydux	42	9	homology	homology	NN
cord-320092-0qnvydux	42	10	and	and	CC
cord-320092-0qnvydux	42	11	sequence	sequence	NN
cord-320092-0qnvydux	42	12	conservation	conservation	NN
cord-320092-0qnvydux	42	13	can	can	MD
cord-320092-0qnvydux	42	14	be	be	VB
cord-320092-0qnvydux	42	15	made	make	VBN
cord-320092-0qnvydux	42	16	at	at	IN
cord-320092-0qnvydux	42	17	present	present	NN
cord-320092-0qnvydux	42	18	without	without	IN
cord-320092-0qnvydux	42	19	a	a	DT
cord-320092-0qnvydux	42	20	concerted	concerted	JJ
cord-320092-0qnvydux	42	21	investigation	investigation	NN
cord-320092-0qnvydux	42	22	focused	focus	VBN
cord-320092-0qnvydux	42	23	on	on	IN
cord-320092-0qnvydux	42	24	this	this	DT
cord-320092-0qnvydux	42	25	topic	topic	NN
cord-320092-0qnvydux	42	26	.	.	.
cord-320092-0qnvydux	43	1	Nevertheless	nevertheless	RB
cord-320092-0qnvydux	43	2	,	,	,
cord-320092-0qnvydux	43	3	the	the	DT
cord-320092-0qnvydux	43	4	similarity	similarity	NN
cord-320092-0qnvydux	43	5	reported	report	VBN
cord-320092-0qnvydux	43	6	here	here	RB
cord-320092-0qnvydux	43	7	raises	raise	VBZ
cord-320092-0qnvydux	43	8	a	a	DT
cord-320092-0qnvydux	43	9	potential	potential	JJ
cord-320092-0qnvydux	43	10	and	and	CC
cord-320092-0qnvydux	43	11	intriguing	intriguing	JJ
cord-320092-0qnvydux	43	12	question	question	NN
cord-320092-0qnvydux	43	13	of	of	IN
cord-320092-0qnvydux	43	14	whether	whether	IN
cord-320092-0qnvydux	43	15	there	there	EX
cord-320092-0qnvydux	43	16	could	could	MD
cord-320092-0qnvydux	43	17	be	be	VB
cord-320092-0qnvydux	43	18	mimicry	mimicry	NN
cord-320092-0qnvydux	43	19	of	of	IN
cord-320092-0qnvydux	43	20	human	human	JJ
cord-320092-0qnvydux	43	21	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	43	22	(	(	-LRB-
cord-320092-0qnvydux	43	23	structural	structural	JJ
cord-320092-0qnvydux	43	24	,	,	,
cord-320092-0qnvydux	43	25	functional	functional	JJ
cord-320092-0qnvydux	43	26	or	or	CC
cord-320092-0qnvydux	43	27	otherwise	otherwise	RB
cord-320092-0qnvydux	43	28	)	)	-RRB-
cord-320092-0qnvydux	43	29	,	,	,
cord-320092-0qnvydux	43	30	perhaps	perhaps	RB
cord-320092-0qnvydux	43	31	inside	inside	IN
cord-320092-0qnvydux	43	32	the	the	DT
cord-320092-0qnvydux	43	33	host	host	NN
cord-320092-0qnvydux	43	34	cell	cell	NN
cord-320092-0qnvydux	43	35	,	,	,
cord-320092-0qnvydux	43	36	by	by	IN
cord-320092-0qnvydux	43	37	the	the	DT
cord-320092-0qnvydux	43	38	TM	TM	NNP
cord-320092-0qnvydux	43	39	-	-	HYPH
cord-320092-0qnvydux	43	40	CT	CT	NNP
cord-320092-0qnvydux	43	41	junction	junction	NN
cord-320092-0qnvydux	43	42	of	of	IN
cord-320092-0qnvydux	43	43	the	the	DT
cord-320092-0qnvydux	43	44	spike	spike	NN
cord-320092-0qnvydux	43	45	protein	protein	NN
cord-320092-0qnvydux	43	46	.	.	.
cord-320092-0qnvydux	44	1	These	these	DT
cord-320092-0qnvydux	44	2	possibilities	possibility	NNS
cord-320092-0qnvydux	44	3	should	should	MD
cord-320092-0qnvydux	44	4	not	not	RB
cord-320092-0qnvydux	44	5	be	be	VB
cord-320092-0qnvydux	44	6	dismissed	dismiss	VBN
cord-320092-0qnvydux	44	7	based	base	VBN
cord-320092-0qnvydux	44	8	on	on	IN
cord-320092-0qnvydux	44	9	the	the	DT
cord-320092-0qnvydux	44	10	mere	mere	JJ
cord-320092-0qnvydux	44	11	phylogenetic	phylogenetic	JJ
cord-320092-0qnvydux	44	12	gap	gap	NN
cord-320092-0qnvydux	44	13	between	between	IN
cord-320092-0qnvydux	44	14	coronaviruses	coronaviruse	NNS
cord-320092-0qnvydux	44	15	and	and	CC
cord-320092-0qnvydux	44	16	vertebrate	vertebrate	JJ
cord-320092-0qnvydux	44	17	species	specie	NNS
cord-320092-0qnvydux	44	18	.	.	.
cord-320092-0qnvydux	45	1	Furthermore	furthermore	RB
cord-320092-0qnvydux	45	2	,	,	,
cord-320092-0qnvydux	45	3	the	the	DT
cord-320092-0qnvydux	45	4	phylogenetic	phylogenetic	JJ
cord-320092-0qnvydux	45	5	gap	gap	NN
cord-320092-0qnvydux	45	6	,	,	,
cord-320092-0qnvydux	45	7	and	and	CC
cord-320092-0qnvydux	45	8	the	the	DT
cord-320092-0qnvydux	45	9	absence	absence	NN
cord-320092-0qnvydux	45	10	of	of	IN
cord-320092-0qnvydux	45	11	clear	clear	JJ
cord-320092-0qnvydux	45	12	evolutionary	evolutionary	JJ
cord-320092-0qnvydux	45	13	homologies	homology	NNS
cord-320092-0qnvydux	45	14	between	between	IN
cord-320092-0qnvydux	45	15	genes	gene	NNS
cord-320092-0qnvydux	45	16	that	that	WDT
cord-320092-0qnvydux	45	17	may	may	MD
cord-320092-0qnvydux	45	18	otherwise	otherwise	RB
cord-320092-0qnvydux	45	19	have	have	VB
cord-320092-0qnvydux	45	20	unexplored	unexplored	JJ
cord-320092-0qnvydux	45	21	functional	functional	JJ
cord-320092-0qnvydux	45	22	linkages	linkage	NNS
cord-320092-0qnvydux	45	23	,	,	,
cord-320092-0qnvydux	45	24	should	should	MD
cord-320092-0qnvydux	45	25	not	not	RB
cord-320092-0qnvydux	45	26	dissuade	dissuade	VB
cord-320092-0qnvydux	45	27	one	one	CD
cord-320092-0qnvydux	45	28	from	from	IN
cord-320092-0qnvydux	45	29	pursuing	pursue	VBG
cord-320092-0qnvydux	45	30	such	such	JJ
cord-320092-0qnvydux	45	31	connections	connection	NNS
cord-320092-0qnvydux	45	32	.	.	.
cord-320092-0qnvydux	46	1	As	as	IN
cord-320092-0qnvydux	46	2	a	a	DT
cord-320092-0qnvydux	46	3	case	case	NN
cord-320092-0qnvydux	46	4	in	in	IN
cord-320092-0qnvydux	46	5	point	point	NN
cord-320092-0qnvydux	46	6	,	,	,
cord-320092-0qnvydux	46	7	gene	gene	NN
cord-320092-0qnvydux	46	8	network	network	NN
cord-320092-0qnvydux	46	9	and	and	CC
cord-320092-0qnvydux	46	10	protein	protein	NN
cord-320092-0qnvydux	46	11	structure	structure	NN
cord-320092-0qnvydux	46	12	/	/	SYM
cord-320092-0qnvydux	46	13	function	function	NN
cord-320092-0qnvydux	46	14	linkages	linkage	NNS
cord-320092-0qnvydux	46	15	between	between	IN
cord-320092-0qnvydux	46	16	certain	certain	JJ
cord-320092-0qnvydux	46	17	yeast	yeast	NN
cord-320092-0qnvydux	46	18	(	(	-LRB-
cord-320092-0qnvydux	46	19	unicellular	unicellular	JJ
cord-320092-0qnvydux	46	20	eukaryotes	eukaryote	NNS
cord-320092-0qnvydux	46	21	)	)	-RRB-
cord-320092-0qnvydux	46	22	and	and	CC
cord-320092-0qnvydux	46	23	mammalian	mammalian	JJ
cord-320092-0qnvydux	46	24	genes	gene	NNS
cord-320092-0qnvydux	46	25	proved	prove	VBD
cord-320092-0qnvydux	46	26	to	to	TO
cord-320092-0qnvydux	46	27	be	be	VB
cord-320092-0qnvydux	46	28	quite	quite	RB
cord-320092-0qnvydux	46	29	beneficial	beneficial	JJ
cord-320092-0qnvydux	46	30	in	in	IN
cord-320092-0qnvydux	46	31	investigating	investigate	VBG
cord-320092-0qnvydux	46	32	neurotoxicity	neurotoxicity	NN
cord-320092-0qnvydux	46	33	in	in	IN
cord-320092-0qnvydux	46	34	human	human	JJ
cord-320092-0qnvydux	46	35	cells	cell	NNS
cord-320092-0qnvydux	46	36	[	[	-LRB-
cord-320092-0qnvydux	46	37	123	123	CD
cord-320092-0qnvydux	46	38	]	]	-RRB-
cord-320092-0qnvydux	46	39	.	.	.
cord-320092-0qnvydux	47	1	The	the	DT
cord-320092-0qnvydux	47	2	question	question	NN
cord-320092-0qnvydux	47	3	now	now	RB
cord-320092-0qnvydux	47	4	is	be	VBZ
cord-320092-0qnvydux	47	5	if	if	IN
cord-320092-0qnvydux	47	6	the	the	DT
cord-320092-0qnvydux	47	7	linkage	linkage	NN
cord-320092-0qnvydux	47	8	between	between	IN
cord-320092-0qnvydux	47	9	the	the	DT
cord-320092-0qnvydux	47	10	spike	spike	NN
cord-320092-0qnvydux	47	11	protein	protein	NN
cord-320092-0qnvydux	47	12	and	and	CC
cord-320092-0qnvydux	47	13	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	47	14	could	could	MD
cord-320092-0qnvydux	47	15	be	be	VB
cord-320092-0qnvydux	47	16	expanded	expand	VBN
cord-320092-0qnvydux	47	17	,	,	,
cord-320092-0qnvydux	47	18	and	and	CC
cord-320092-0qnvydux	47	19	what	what	WDT
cord-320092-0qnvydux	47	20	reasonable	reasonable	JJ
cord-320092-0qnvydux	47	21	scenarios	scenario	NNS
cord-320092-0qnvydux	47	22	for	for	IN
cord-320092-0qnvydux	47	23	its	-PRON-	PRP$
cord-320092-0qnvydux	47	24	experimental	experimental	JJ
cord-320092-0qnvydux	47	25	validation	validation	NN
cord-320092-0qnvydux	47	26	could	could	MD
cord-320092-0qnvydux	47	27	be	be	VB
cord-320092-0qnvydux	47	28	envisaged	envisage	VBN
cord-320092-0qnvydux	47	29	.	.	.
cord-320092-0qnvydux	48	1	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	48	2	is	be	VBZ
cord-320092-0qnvydux	48	3	a	a	DT
cord-320092-0qnvydux	48	4	small	small	JJ
cord-320092-0qnvydux	48	5	peptide	peptide	JJ
cord-320092-0qnvydux	48	6	hormone	hormone	NN
cord-320092-0qnvydux	48	7	that	that	WDT
cord-320092-0qnvydux	48	8	was	be	VBD
cord-320092-0qnvydux	48	9	discovered	discover	VBN
cord-320092-0qnvydux	48	10	in	in	IN
cord-320092-0qnvydux	48	11	2000/2001	2000/2001	CD
cord-320092-0qnvydux	48	12	[	[	-LRB-
cord-320092-0qnvydux	48	13	7	7	CD
cord-320092-0qnvydux	48	14	,	,	,
cord-320092-0qnvydux	48	15	63	63	CD
cord-320092-0qnvydux	48	16	,	,	,
cord-320092-0qnvydux	48	17	69	69	CD
cord-320092-0qnvydux	48	18	,	,	,
cord-320092-0qnvydux	48	19	96	96	CD
cord-320092-0qnvydux	48	20	,	,	,
cord-320092-0qnvydux	48	21	102	102	CD
cord-320092-0qnvydux	48	22	]	]	-RRB-
cord-320092-0qnvydux	48	23	,	,	,
cord-320092-0qnvydux	48	24	and	and	CC
cord-320092-0qnvydux	48	25	initially	initially	RB
cord-320092-0qnvydux	48	26	named	name	VBD
cord-320092-0qnvydux	48	27	LEAP-1	LEAP-1	NNP
cord-320092-0qnvydux	48	28	(	(	-LRB-
cord-320092-0qnvydux	48	29	liver	liver	NN
cord-320092-0qnvydux	48	30	-	-	HYPH
cord-320092-0qnvydux	48	31	expressed	express	VBN
cord-320092-0qnvydux	48	32	antimicrobial	antimicrobial	JJ
cord-320092-0qnvydux	48	33	peptide	peptide	NN
cord-320092-0qnvydux	48	34	)	)	-RRB-
cord-320092-0qnvydux	48	35	.	.	.
cord-320092-0qnvydux	49	1	It	-PRON-	PRP
cord-320092-0qnvydux	49	2	has	have	VBZ
cord-320092-0qnvydux	49	3	an	an	DT
cord-320092-0qnvydux	49	4	antiparallel	antiparallel	JJ
cord-320092-0qnvydux	49	5	beta	beta	NN
cord-320092-0qnvydux	49	6	-	-	HYPH
cord-320092-0qnvydux	49	7	sheet	sheet	NN
cord-320092-0qnvydux	49	8	fold	fold	NN
cord-320092-0qnvydux	49	9	and	and	CC
cord-320092-0qnvydux	49	10	contains	contain	VBZ
cord-320092-0qnvydux	49	11	four	four	CD
cord-320092-0qnvydux	49	12	disulfide	disulfide	JJ
cord-320092-0qnvydux	49	13	bonds	bond	NNS
cord-320092-0qnvydux	49	14	,	,	,
cord-320092-0qnvydux	49	15	and	and	CC
cord-320092-0qnvydux	49	16	is	be	VBZ
cord-320092-0qnvydux	49	17	involved	involve	VBN
cord-320092-0qnvydux	49	18	in	in	IN
cord-320092-0qnvydux	49	19	iron	iron	NN
cord-320092-0qnvydux	49	20	trafficking	trafficking	NN
cord-320092-0qnvydux	49	21	and	and	CC
cord-320092-0qnvydux	49	22	the	the	DT
cord-320092-0qnvydux	49	23	host	host	NN
cord-320092-0qnvydux	49	24	's	's	POS
cord-320092-0qnvydux	49	25	response	response	NN
cord-320092-0qnvydux	49	26	to	to	IN
cord-320092-0qnvydux	49	27	infection	infection	NN
cord-320092-0qnvydux	49	28	[	[	-LRB-
cord-320092-0qnvydux	49	29	34	34	CD
cord-320092-0qnvydux	49	30	]	]	-RRB-
cord-320092-0qnvydux	49	31	.	.	.
cord-320092-0qnvydux	50	1	In	in	IN
cord-320092-0qnvydux	50	2	fact	fact	NN
cord-320092-0qnvydux	50	3	,	,	,
cord-320092-0qnvydux	50	4	it	-PRON-	PRP
cord-320092-0qnvydux	50	5	has	have	VBZ
cord-320092-0qnvydux	50	6	been	be	VBN
cord-320092-0qnvydux	50	7	remarked	remark	VBN
cord-320092-0qnvydux	50	8	by	by	IN
cord-320092-0qnvydux	50	9	a	a	DT
cord-320092-0qnvydux	50	10	number	number	NN
cord-320092-0qnvydux	50	11	of	of	IN
cord-320092-0qnvydux	50	12	commentators	commentator	NNS
cord-320092-0qnvydux	50	13	that	that	IN
cord-320092-0qnvydux	50	14	"	"	``
cord-320092-0qnvydux	50	15	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	50	16	is	be	VBZ
cord-320092-0qnvydux	50	17	to	to	TO
cord-320092-0qnvydux	50	18	iron	iron	NN
cord-320092-0qnvydux	50	19	,	,	,
cord-320092-0qnvydux	50	20	what	what	WDT
cord-320092-0qnvydux	50	21	insulin	insulin	NN
cord-320092-0qnvydux	50	22	is	be	VBZ
cord-320092-0qnvydux	50	23	to	to	IN
cord-320092-0qnvydux	50	24	glucose	glucose	VB
cord-320092-0qnvydux	50	25	"	"	''
cord-320092-0qnvydux	50	26	[	[	-LRB-
cord-320092-0qnvydux	50	27	57	57	CD
cord-320092-0qnvydux	50	28	]	]	-RRB-
cord-320092-0qnvydux	50	29	.	.	.
cord-320092-0qnvydux	51	1	Clear	clear	JJ
cord-320092-0qnvydux	51	2	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	51	3	orthologs	ortholog	NNS
cord-320092-0qnvydux	51	4	appear	appear	VBP
cord-320092-0qnvydux	51	5	to	to	TO
cord-320092-0qnvydux	51	6	be	be	VB
cord-320092-0qnvydux	51	7	missing	miss	VBG
cord-320092-0qnvydux	51	8	in	in	IN
cord-320092-0qnvydux	51	9	birds	bird	NNS
cord-320092-0qnvydux	51	10	and	and	CC
cord-320092-0qnvydux	51	11	invertebrates	invertebrate	NNS
cord-320092-0qnvydux	51	12	[	[	-LRB-
cord-320092-0qnvydux	51	13	105	105	CD
cord-320092-0qnvydux	51	14	]	]	-RRB-
cord-320092-0qnvydux	51	15	.	.	.
cord-320092-0qnvydux	52	1	The	the	DT
cord-320092-0qnvydux	52	2	human	human	JJ
cord-320092-0qnvydux	52	3	hepcidin	hepcidin	NN
cord-320092-0qnvydux	52	4	(	(	-LRB-
cord-320092-0qnvydux	52	5	encoded	encode	VBN
cord-320092-0qnvydux	52	6	by	by	IN
cord-320092-0qnvydux	52	7	the	the	DT
cord-320092-0qnvydux	52	8	HAMP	HAMP	NNP
cord-320092-0qnvydux	52	9	gene	gene	NN
cord-320092-0qnvydux	52	10	on	on	IN
cord-320092-0qnvydux	52	11	chromosome	chromosome	NN
cord-320092-0qnvydux	52	12	19q13	19q13	CD
cord-320092-0qnvydux	52	13	)	)	-RRB-
cord-320092-0qnvydux	52	14	is	be	VBZ
cord-320092-0qnvydux	52	15	an	an	DT
cord-320092-0qnvydux	52	16	84-amino	84-amino	CD
cord-320092-0qnvydux	52	17	-	-	HYPH
cord-320092-0qnvydux	52	18	acid	acid	NN
cord-320092-0qnvydux	52	19	prepropeptide	prepropeptide	NN
cord-320092-0qnvydux	52	20	,	,	,
cord-320092-0qnvydux	52	21	leading	lead	VBG
cord-320092-0qnvydux	52	22	to	to	IN
cord-320092-0qnvydux	52	23	a	a	DT
cord-320092-0qnvydux	52	24	mature	mature	JJ
cord-320092-0qnvydux	52	25	25-amino	25-amino	CD
cord-320092-0qnvydux	52	26	-	-	HYPH
cord-320092-0qnvydux	52	27	acid	acid	NN
cord-320092-0qnvydux	52	28	peptide	peptide	NN
cord-320092-0qnvydux	52	29	that	that	WDT
cord-320092-0qnvydux	52	30	is	be	VBZ
cord-320092-0qnvydux	52	31	detectable	detectable	JJ
cord-320092-0qnvydux	52	32	in	in	IN
cord-320092-0qnvydux	52	33	blood	blood	NN
cord-320092-0qnvydux	52	34	and	and	CC
cord-320092-0qnvydux	52	35	urine	urine	NN
cord-320092-0qnvydux	52	36	[	[	-LRB-
cord-320092-0qnvydux	52	37	65	65	CD
cord-320092-0qnvydux	52	38	]	]	-RRB-
cord-320092-0qnvydux	52	39	.	.	.
cord-320092-0qnvydux	53	1	The	the	DT
cord-320092-0qnvydux	53	2	proprotein	proprotein	NNP
cord-320092-0qnvydux	53	3	convertase	convertase	NN
cord-320092-0qnvydux	53	4	furin	furin	NN
cord-320092-0qnvydux	53	5	has	have	VBZ
cord-320092-0qnvydux	53	6	been	be	VBN
cord-320092-0qnvydux	53	7	demonstrated	demonstrate	VBN
cord-320092-0qnvydux	53	8	to	to	TO
cord-320092-0qnvydux	53	9	cleave	cleave	VB
cord-320092-0qnvydux	53	10	prohepcidin	prohepcidin	NNS
cord-320092-0qnvydux	53	11	at	at	IN
cord-320092-0qnvydux	53	12	a	a	DT
cord-320092-0qnvydux	53	13	polybasic	polybasic	JJ
cord-320092-0qnvydux	53	14	site	site	NN
cord-320092-0qnvydux	53	15	[	[	-LRB-
cord-320092-0qnvydux	53	16	73	73	CD
cord-320092-0qnvydux	53	17	,	,	,
cord-320092-0qnvydux	53	18	124	124	CD
cord-320092-0qnvydux	53	19	]	]	-RRB-
cord-320092-0qnvydux	53	20	.	.	.
cord-320092-0qnvydux	54	1	Of	of	IN
cord-320092-0qnvydux	54	2	note	note	NN
cord-320092-0qnvydux	54	3	,	,	,
cord-320092-0qnvydux	54	4	a	a	DT
cord-320092-0qnvydux	54	5	furin	furin	NN
cord-320092-0qnvydux	54	6	-	-	HYPH
cord-320092-0qnvydux	54	7	like	like	JJ
cord-320092-0qnvydux	54	8	cleavage	cleavage	NN
cord-320092-0qnvydux	54	9	site	site	NN
cord-320092-0qnvydux	54	10	(	(	-LRB-
cord-320092-0qnvydux	54	11	'	'	``
cord-320092-0qnvydux	54	12	RRAR	RRAR	NNP
cord-320092-0qnvydux	54	13	'	'	''
cord-320092-0qnvydux	54	14	)	)	-RRB-
cord-320092-0qnvydux	54	15	has	have	VBZ
cord-320092-0qnvydux	54	16	been	be	VBN
cord-320092-0qnvydux	54	17	reported	report	VBN
cord-320092-0qnvydux	54	18	to	to	TO
cord-320092-0qnvydux	54	19	exist	exist	VB
cord-320092-0qnvydux	54	20	in	in	IN
cord-320092-0qnvydux	54	21	the	the	DT
cord-320092-0qnvydux	54	22	ectodomain	ectodomain	NN
cord-320092-0qnvydux	54	23	of	of	IN
cord-320092-0qnvydux	54	24	the	the	DT
cord-320092-0qnvydux	54	25	SARS	SARS	NNP
cord-320092-0qnvydux	54	26	-	-	HYPH
cord-320092-0qnvydux	54	27	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	54	28	spike	spike	NN
cord-320092-0qnvydux	54	29	protein	protein	NN
cord-320092-0qnvydux	54	30	,	,	,
cord-320092-0qnvydux	54	31	which	which	WDT
cord-320092-0qnvydux	54	32	is	be	VBZ
cord-320092-0qnvydux	54	33	Fig	Fig	NNP
cord-320092-0qnvydux	54	34	.	.	.
cord-320092-0qnvydux	55	1	1	1	CD
cord-320092-0qnvydux	55	2	Comparison	comparison	NN
cord-320092-0qnvydux	55	3	of	of	IN
cord-320092-0qnvydux	55	4	select	select	JJ
cord-320092-0qnvydux	55	5	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	55	6	and	and	CC
cord-320092-0qnvydux	55	7	coronavirus	coronavirus	NN
cord-320092-0qnvydux	55	8	spike	spike	NN
cord-320092-0qnvydux	55	9	protein	protein	NN
cord-320092-0qnvydux	55	10	sequences	sequence	NNS
cord-320092-0qnvydux	55	11	.	.	.
cord-320092-0qnvydux	56	1	a	a	DT
cord-320092-0qnvydux	56	2	A	a	DT
cord-320092-0qnvydux	56	3	multiple	multiple	JJ
cord-320092-0qnvydux	56	4	sequence	sequence	NN
cord-320092-0qnvydux	56	5	alignment	alignment	NN
cord-320092-0qnvydux	56	6	of	of	IN
cord-320092-0qnvydux	56	7	the	the	DT
cord-320092-0qnvydux	56	8	C	C	NNP
cord-320092-0qnvydux	56	9	-	-	HYPH
cord-320092-0qnvydux	56	10	terminal	terminal	NN
cord-320092-0qnvydux	56	11	region	region	NN
cord-320092-0qnvydux	56	12	of	of	IN
cord-320092-0qnvydux	56	13	a	a	DT
cord-320092-0qnvydux	56	14	number	number	NN
cord-320092-0qnvydux	56	15	of	of	IN
cord-320092-0qnvydux	56	16	coronavirus	coronavirus	NN
cord-320092-0qnvydux	56	17	spike	spike	NN
cord-320092-0qnvydux	56	18	proteins	protein	NNS
cord-320092-0qnvydux	56	19	(	(	-LRB-
cord-320092-0qnvydux	56	20	encompassing	encompass	VBG
cord-320092-0qnvydux	56	21	portions	portion	NNS
cord-320092-0qnvydux	56	22	of	of	IN
cord-320092-0qnvydux	56	23	the	the	DT
cord-320092-0qnvydux	56	24	putative	putative	JJ
cord-320092-0qnvydux	56	25	transmembrane	transmembrane	NN
cord-320092-0qnvydux	56	26	and	and	CC
cord-320092-0qnvydux	56	27	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	56	28	tail	tail	NN
cord-320092-0qnvydux	56	29	segments	segment	NNS
cord-320092-0qnvydux	56	30	)	)	-RRB-
cord-320092-0qnvydux	56	31	,	,	,
cord-320092-0qnvydux	56	32	four	four	CD
cord-320092-0qnvydux	56	33	hepcidins	hepcidin	NNS
cord-320092-0qnvydux	56	34	and	and	CC
cord-320092-0qnvydux	56	35	the	the	DT
cord-320092-0qnvydux	56	36	SARS	SARS	NNP
cord-320092-0qnvydux	56	37	-	-	HYPH
cord-320092-0qnvydux	56	38	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	56	39	envelope	envelope	NN
cord-320092-0qnvydux	56	40	protein	protein	NN
cord-320092-0qnvydux	56	41	is	be	VBZ
cord-320092-0qnvydux	56	42	presented	present	VBN
cord-320092-0qnvydux	56	43	.	.	.
cord-320092-0qnvydux	57	1	The	the	DT
cord-320092-0qnvydux	57	2	envelope	envelope	NN
cord-320092-0qnvydux	57	3	sequence	sequence	NN
cord-320092-0qnvydux	57	4	is	be	VBZ
cord-320092-0qnvydux	57	5	provided	provide	VBN
cord-320092-0qnvydux	57	6	only	only	RB
cord-320092-0qnvydux	57	7	to	to	TO
cord-320092-0qnvydux	57	8	demonstrate	demonstrate	VB
cord-320092-0qnvydux	57	9	the	the	DT
cord-320092-0qnvydux	57	10	cysteine	cysteine	NN
cord-320092-0qnvydux	57	11	residues	residue	NNS
cord-320092-0qnvydux	57	12	with	with	IN
cord-320092-0qnvydux	57	13	which	which	WDT
cord-320092-0qnvydux	57	14	the	the	DT
cord-320092-0qnvydux	57	15	spike	spike	NN
cord-320092-0qnvydux	57	16	protein	protein	NN
cord-320092-0qnvydux	57	17	is	be	VBZ
cord-320092-0qnvydux	57	18	proposed	propose	VBN
cord-320092-0qnvydux	57	19	to	to	TO
cord-320092-0qnvydux	57	20	form	form	VB
cord-320092-0qnvydux	57	21	disulfide	disulfide	JJ
cord-320092-0qnvydux	57	22	bridges	bridge	NNS
cord-320092-0qnvydux	57	23	[	[	-LRB-
cord-320092-0qnvydux	57	24	135	135	CD
cord-320092-0qnvydux	57	25	]	]	-RRB-
cord-320092-0qnvydux	57	26	.	.	.
cord-320092-0qnvydux	58	1	The	the	DT
cord-320092-0qnvydux	58	2	residue	residue	NN
cord-320092-0qnvydux	58	3	numbers	number	NNS
cord-320092-0qnvydux	58	4	are	be	VBP
cord-320092-0qnvydux	58	5	shown	show	VBN
cord-320092-0qnvydux	58	6	on	on	IN
cord-320092-0qnvydux	58	7	the	the	DT
cord-320092-0qnvydux	58	8	sides	side	NNS
cord-320092-0qnvydux	58	9	of	of	IN
cord-320092-0qnvydux	58	10	each	each	DT
cord-320092-0qnvydux	58	11	protein	protein	NN
cord-320092-0qnvydux	58	12	segment	segment	NN
cord-320092-0qnvydux	58	13	,	,	,
cord-320092-0qnvydux	58	14	and	and	CC
cord-320092-0qnvydux	58	15	for	for	IN
cord-320092-0qnvydux	58	16	proteins	protein	NNS
cord-320092-0qnvydux	58	17	whose	whose	WP$
cord-320092-0qnvydux	58	18	C	c	NN
cord-320092-0qnvydux	58	19	-	-	HYPH
cord-320092-0qnvydux	58	20	terminal	terminal	NN
cord-320092-0qnvydux	58	21	sequences	sequence	NNS
cord-320092-0qnvydux	58	22	continue	continue	VBP
cord-320092-0qnvydux	58	23	beyond	beyond	IN
cord-320092-0qnvydux	58	24	the	the	DT
cord-320092-0qnvydux	58	25	alignment	alignment	NN
cord-320092-0qnvydux	58	26	,	,	,
cord-320092-0qnvydux	58	27	the	the	DT
cord-320092-0qnvydux	58	28	full	full	JJ
cord-320092-0qnvydux	58	29	residue	residue	NN
cord-320092-0qnvydux	58	30	length	length	NN
cord-320092-0qnvydux	58	31	is	be	VBZ
cord-320092-0qnvydux	58	32	provided	provide	VBN
cord-320092-0qnvydux	58	33	to	to	IN
cord-320092-0qnvydux	58	34	the	the	DT
cord-320092-0qnvydux	58	35	right	right	NN
cord-320092-0qnvydux	58	36	.	.	.
cord-320092-0qnvydux	59	1	As	as	IN
cord-320092-0qnvydux	59	2	per	per	IN
cord-320092-0qnvydux	59	3	a	a	DT
cord-320092-0qnvydux	59	4	color	color	NN
cord-320092-0qnvydux	59	5	scheme	scheme	NN
cord-320092-0qnvydux	59	6	used	use	VBN
cord-320092-0qnvydux	59	7	previously	previously	RB
cord-320092-0qnvydux	59	8	[	[	-LRB-
cord-320092-0qnvydux	59	9	111	111	CD
cord-320092-0qnvydux	59	10	]	]	-RRB-
cord-320092-0qnvydux	59	11	,	,	,
cord-320092-0qnvydux	59	12	dark	dark	JJ
cord-320092-0qnvydux	59	13	green	green	JJ
cord-320092-0qnvydux	59	14	,	,	,
cord-320092-0qnvydux	59	15	grey	grey	JJ
cord-320092-0qnvydux	59	16	and	and	CC
cord-320092-0qnvydux	59	17	black	black	JJ
cord-320092-0qnvydux	59	18	highlights	highlight	NNS
cord-320092-0qnvydux	59	19	depict	depict	VBP
cord-320092-0qnvydux	59	20	conserved	conserve	VBN
cord-320092-0qnvydux	59	21	,	,	,
cord-320092-0qnvydux	59	22	similar	similar	JJ
cord-320092-0qnvydux	59	23	and	and	CC
cord-320092-0qnvydux	59	24	identical	identical	JJ
cord-320092-0qnvydux	59	25	residues	residue	NNS
cord-320092-0qnvydux	59	26	,	,	,
cord-320092-0qnvydux	59	27	respectively	respectively	RB
cord-320092-0qnvydux	59	28	.	.	.
cord-320092-0qnvydux	59	29	'	'	''
cord-320092-0qnvydux	60	1	Tr	Tr	NNP
cord-320092-0qnvydux	60	2	'	'	POS
cord-320092-0qnvydux	60	3	stands	stand	NNS
cord-320092-0qnvydux	60	4	for	for	IN
cord-320092-0qnvydux	60	5	Takifugu	Takifugu	NNP
cord-320092-0qnvydux	60	6	rubripes	rubripe	NNS
cord-320092-0qnvydux	60	7	(	(	-LRB-
cord-320092-0qnvydux	60	8	Japanese	japanese	JJ
cord-320092-0qnvydux	60	9	pufferfish	pufferfish	NN
cord-320092-0qnvydux	60	10	)	)	-RRB-
cord-320092-0qnvydux	61	1	,	,	,
cord-320092-0qnvydux	61	2	'	'	``
cord-320092-0qnvydux	61	3	Rf	rf	NN
cord-320092-0qnvydux	61	4	'	'	''
cord-320092-0qnvydux	61	5	for	for	IN
cord-320092-0qnvydux	61	6	Rhinolophus	Rhinolophus	NNP
cord-320092-0qnvydux	61	7	ferrumequinum	ferrumequinum	NNP
cord-320092-0qnvydux	61	8	(	(	-LRB-
cord-320092-0qnvydux	61	9	greater	great	JJR
cord-320092-0qnvydux	61	10	horseshoe	horseshoe	NN
cord-320092-0qnvydux	61	11	bat	bat	NN
cord-320092-0qnvydux	61	12	)	)	-RRB-
cord-320092-0qnvydux	61	13	and	and	CC
cord-320092-0qnvydux	61	14	'	'	``
cord-320092-0qnvydux	61	15	Hs	Hs	NNP
cord-320092-0qnvydux	61	16	'	'	''
cord-320092-0qnvydux	61	17	for	for	IN
cord-320092-0qnvydux	61	18	Homo	homo	NN
cord-320092-0qnvydux	61	19	sapiens	sapiens	JJ
cord-320092-0qnvydux	61	20	(	(	-LRB-
cord-320092-0qnvydux	61	21	human	human	NN
cord-320092-0qnvydux	61	22	)	)	-RRB-
cord-320092-0qnvydux	61	23	.	.	.
cord-320092-0qnvydux	62	1	The	the	DT
cord-320092-0qnvydux	62	2	protein	protein	NN
cord-320092-0qnvydux	62	3	accession	accession	NN
cord-320092-0qnvydux	62	4	numbers	number	NNS
cord-320092-0qnvydux	62	5	of	of	IN
cord-320092-0qnvydux	62	6	the	the	DT
cord-320092-0qnvydux	62	7	sequences	sequence	NNS
cord-320092-0qnvydux	62	8	shown	show	VBN
cord-320092-0qnvydux	62	9	are	be	VBP
cord-320092-0qnvydux	62	10	,	,	,
cord-320092-0qnvydux	62	11	in	in	IN
cord-320092-0qnvydux	62	12	order	order	NN
cord-320092-0qnvydux	62	13	:	:	:
cord-320092-0qnvydux	63	1	(	(	-LRB-
cord-320092-0qnvydux	63	2	1	1	LS
cord-320092-0qnvydux	63	3	)	)	-RRB-
cord-320092-0qnvydux	63	4	AWH65954.1	AWH65954.1	NNP
cord-320092-0qnvydux	63	5	,	,	,
cord-320092-0qnvydux	63	6	(	(	-LRB-
cord-320092-0qnvydux	63	7	2	2	LS
cord-320092-0qnvydux	63	8	)	)	-RRB-
cord-320092-0qnvydux	63	9	YP_009724390.1	YP_009724390.1	NNP
cord-320092-0qnvydux	63	10	,	,	,
cord-320092-0qnvydux	63	11	(	(	-LRB-
cord-320092-0qnvydux	63	12	3	3	LS
cord-320092-0qnvydux	63	13	)	)	-RRB-
cord-320092-0qnvydux	63	14	ANA96027.1	ANA96027.1	NNP
cord-320092-0qnvydux	63	15	,	,	,
cord-320092-0qnvydux	63	16	(	(	-LRB-
cord-320092-0qnvydux	63	17	4	4	CD
cord-320092-0qnvydux	63	18	)	)	-RRB-
cord-320092-0qnvydux	63	19	XP_003965681.1	xp_003965681.1	NN
cord-320092-0qnvydux	63	20	,	,	,
cord-320092-0qnvydux	63	21	(	(	-LRB-
cord-320092-0qnvydux	63	22	5	5	LS
cord-320092-0qnvydux	63	23	)	)	-RRB-
cord-320092-0qnvydux	63	24	XP_029694670.1	XP_029694670.1	NNS
cord-320092-0qnvydux	63	25	,	,	,
cord-320092-0qnvydux	63	26	(	(	-LRB-
cord-320092-0qnvydux	63	27	6	6	LS
cord-320092-0qnvydux	63	28	)	)	-RRB-
cord-320092-0qnvydux	63	29	ENSRFET00010014064.1	ENSRFET00010014064.1	NNP
cord-320092-0qnvydux	63	30	,	,	,
cord-320092-0qnvydux	63	31	(	(	-LRB-
cord-320092-0qnvydux	63	32	7	7	CD
cord-320092-0qnvydux	63	33	)	)	-RRB-
cord-320092-0qnvydux	63	34	NP_066998.1	NP_066998.1	NNP
cord-320092-0qnvydux	63	35	and	and	CC
cord-320092-0qnvydux	63	36	(	(	-LRB-
cord-320092-0qnvydux	63	37	8)	8)	NNP
cord-320092-0qnvydux	64	1	QHD43418.1	QHD43418.1	NNP
cord-320092-0qnvydux	64	2	.	.	.
cord-320092-0qnvydux	65	1	The	the	DT
cord-320092-0qnvydux	65	2	domain	domain	NN
cord-320092-0qnvydux	65	3	illustration	illustration	NN
cord-320092-0qnvydux	65	4	of	of	IN
cord-320092-0qnvydux	65	5	the	the	DT
cord-320092-0qnvydux	65	6	spike	spike	NN
cord-320092-0qnvydux	65	7	protein	protein	NN
cord-320092-0qnvydux	65	8	is	be	VBZ
cord-320092-0qnvydux	65	9	based	base	VBN
cord-320092-0qnvydux	65	10	on	on	IN
cord-320092-0qnvydux	65	11	ref	ref	NN
cord-320092-0qnvydux	65	12	.	.	.
cord-320092-0qnvydux	66	1	[	[	-LRB-
cord-320092-0qnvydux	66	2	132	132	CD
cord-320092-0qnvydux	66	3	]	]	-RRB-
cord-320092-0qnvydux	66	4	.	.	.
cord-320092-0qnvydux	67	1	b	b	LS
cord-320092-0qnvydux	67	2	A	a	DT
cord-320092-0qnvydux	67	3	solved	solve	VBN
cord-320092-0qnvydux	67	4	NMR	NMR	NNP
cord-320092-0qnvydux	67	5	structure	structure	NN
cord-320092-0qnvydux	67	6	of	of	IN
cord-320092-0qnvydux	67	7	human	human	JJ
cord-320092-0qnvydux	67	8	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	67	9	[	[	-LRB-
cord-320092-0qnvydux	67	10	65	65	CD
cord-320092-0qnvydux	67	11	]	]	-RRB-
cord-320092-0qnvydux	68	1	(	(	-LRB-
cord-320092-0qnvydux	68	2	PDB	PDB	NNP
cord-320092-0qnvydux	68	3	:	:	:
cord-320092-0qnvydux	68	4	2KEF	2kef	LS
cord-320092-0qnvydux	68	5	)	)	-RRB-
cord-320092-0qnvydux	68	6	,	,	,
cord-320092-0qnvydux	68	7	adopting	adopt	VBG
cord-320092-0qnvydux	68	8	an	an	DT
cord-320092-0qnvydux	68	9	antiparallel	antiparallel	JJ
cord-320092-0qnvydux	68	10	beta	beta	NN
cord-320092-0qnvydux	68	11	-	-	HYPH
cord-320092-0qnvydux	68	12	sheet	sheet	NN
cord-320092-0qnvydux	68	13	fold	fold	NN
cord-320092-0qnvydux	68	14	,	,	,
cord-320092-0qnvydux	68	15	is	be	VBZ
cord-320092-0qnvydux	68	16	visualized	visualize	VBN
cord-320092-0qnvydux	68	17	with	with	IN
cord-320092-0qnvydux	68	18	its	-PRON-	PRP$
cord-320092-0qnvydux	68	19	putative	putative	JJ
cord-320092-0qnvydux	68	20	four	four	CD
cord-320092-0qnvydux	68	21	disulfide	disulfide	NN
cord-320092-0qnvydux	68	22	bonds	bond	NNS
cord-320092-0qnvydux	68	23	formed	form	VBN
cord-320092-0qnvydux	68	24	between	between	IN
cord-320092-0qnvydux	68	25	eight	eight	CD
cord-320092-0qnvydux	68	26	cysteine	cysteine	NN
cord-320092-0qnvydux	68	27	residues	residue	NNS
cord-320092-0qnvydux	68	28	.	.	.
cord-320092-0qnvydux	69	1	c	c	NNP
cord-320092-0qnvydux	70	1	The	the	DT
cord-320092-0qnvydux	70	2	position	position	NN
cord-320092-0qnvydux	70	3	of	of	IN
cord-320092-0qnvydux	70	4	the	the	DT
cord-320092-0qnvydux	70	5	disulfide	disulfide	JJ
cord-320092-0qnvydux	70	6	bonds	bond	NNS
cord-320092-0qnvydux	70	7	in	in	IN
cord-320092-0qnvydux	70	8	the	the	DT
cord-320092-0qnvydux	70	9	sequence	sequence	NN
cord-320092-0qnvydux	70	10	of	of	IN
cord-320092-0qnvydux	70	11	the	the	DT
cord-320092-0qnvydux	70	12	mature	mature	JJ
cord-320092-0qnvydux	70	13	human	human	JJ
cord-320092-0qnvydux	70	14	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	70	15	is	be	VBZ
cord-320092-0qnvydux	70	16	illustrated	illustrate	VBN
cord-320092-0qnvydux	70	17	along	along	IN
cord-320092-0qnvydux	70	18	with	with	IN
cord-320092-0qnvydux	70	19	the	the	DT
cord-320092-0qnvydux	70	20	potential	potential	JJ
cord-320092-0qnvydux	70	21	palmitoylation	palmitoylation	NN
cord-320092-0qnvydux	70	22	residues	residue	NNS
cord-320092-0qnvydux	70	23	(	(	-LRB-
cord-320092-0qnvydux	70	24	ten	ten	CD
cord-320092-0qnvydux	70	25	cysteines	cysteine	NNS
cord-320092-0qnvydux	70	26	)	)	-RRB-
cord-320092-0qnvydux	70	27	of	of	IN
cord-320092-0qnvydux	70	28	the	the	DT
cord-320092-0qnvydux	70	29	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	70	30	tail	tail	NN
cord-320092-0qnvydux	70	31	of	of	IN
cord-320092-0qnvydux	70	32	the	the	DT
cord-320092-0qnvydux	70	33	SARS	SARS	NNP
cord-320092-0qnvydux	70	34	-	-	HYPH
cord-320092-0qnvydux	70	35	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	70	36	spike	spike	NN
cord-320092-0qnvydux	70	37	protein	protein	NN
cord-320092-0qnvydux	70	38	.	.	.
cord-320092-0qnvydux	71	1	The	the	DT
cord-320092-0qnvydux	71	2	palmitate	palmitate	NN
cord-320092-0qnvydux	71	3	visual	visual	NN
cord-320092-0qnvydux	71	4	is	be	VBZ
cord-320092-0qnvydux	71	5	as	as	IN
cord-320092-0qnvydux	71	6	per	per	IN
cord-320092-0qnvydux	71	7	ref	ref	NN
cord-320092-0qnvydux	71	8	.	.	.
cord-320092-0qnvydux	72	1	[	[	-LRB-
cord-320092-0qnvydux	72	2	77	77	CD
cord-320092-0qnvydux	72	3	]	]	-RRB-
cord-320092-0qnvydux	72	4	with	with	IN
cord-320092-0qnvydux	72	5	permission	permission	NN
cord-320092-0qnvydux	72	6	from	from	IN
cord-320092-0qnvydux	72	7	the	the	DT
cord-320092-0qnvydux	72	8	publisher	publisher	NN
cord-320092-0qnvydux	72	9	(	(	-LRB-
cord-320092-0qnvydux	72	10	Springer	Springer	NNP
cord-320092-0qnvydux	72	11	Nature	Nature	NNP
cord-320092-0qnvydux	72	12	)	)	-RRB-
cord-320092-0qnvydux	72	13	absent	absent	JJ
cord-320092-0qnvydux	72	14	in	in	IN
cord-320092-0qnvydux	72	15	coronaviruses	coronaviruse	NNS
cord-320092-0qnvydux	72	16	of	of	IN
cord-320092-0qnvydux	72	17	the	the	DT
cord-320092-0qnvydux	72	18	same	same	JJ
cord-320092-0qnvydux	72	19	clade	clade	NN
cord-320092-0qnvydux	72	20	[	[	-LRB-
cord-320092-0qnvydux	72	21	5	5	CD
cord-320092-0qnvydux	72	22	,	,	,
cord-320092-0qnvydux	72	23	28	28	CD
cord-320092-0qnvydux	72	24	]	]	-RRB-
cord-320092-0qnvydux	72	25	.	.	.
cord-320092-0qnvydux	73	1	The	the	DT
cord-320092-0qnvydux	73	2	protein	protein	NN
cord-320092-0qnvydux	73	3	-	-	HYPH
cord-320092-0qnvydux	73	4	coding	code	VBG
cord-320092-0qnvydux	73	5	part	part	NN
cord-320092-0qnvydux	73	6	of	of	IN
cord-320092-0qnvydux	73	7	the	the	DT
cord-320092-0qnvydux	73	8	HAMP	HAMP	NNP
cord-320092-0qnvydux	73	9	gene	gene	NN
cord-320092-0qnvydux	73	10	is	be	VBZ
cord-320092-0qnvydux	73	11	split	split	VBN
cord-320092-0qnvydux	73	12	over	over	IN
cord-320092-0qnvydux	73	13	three	three	CD
cord-320092-0qnvydux	73	14	exons	exon	NNS
cord-320092-0qnvydux	73	15	,	,	,
cord-320092-0qnvydux	73	16	with	with	IN
cord-320092-0qnvydux	73	17	the	the	DT
cord-320092-0qnvydux	73	18	25-amino	25-amino	CD
cord-320092-0qnvydux	73	19	-	-	HYPH
cord-320092-0qnvydux	73	20	acid	acid	NN
cord-320092-0qnvydux	73	21	mature	mature	JJ
cord-320092-0qnvydux	73	22	peptide	peptide	NN
cord-320092-0qnvydux	73	23	occurring	occur	VBG
cord-320092-0qnvydux	73	24	on	on	IN
cord-320092-0qnvydux	73	25	the	the	DT
cord-320092-0qnvydux	73	26	last	last	JJ
cord-320092-0qnvydux	73	27	exon	exon	NN
cord-320092-0qnvydux	73	28	.	.	.
cord-320092-0qnvydux	74	1	In	in	IN
cord-320092-0qnvydux	74	2	terms	term	NNS
cord-320092-0qnvydux	74	3	of	of	IN
cord-320092-0qnvydux	74	4	its	-PRON-	PRP$
cord-320092-0qnvydux	74	5	putative	putative	JJ
cord-320092-0qnvydux	74	6	function	function	NN
cord-320092-0qnvydux	74	7	,	,	,
cord-320092-0qnvydux	74	8	Prentice	Prentice	NNP
cord-320092-0qnvydux	74	9	notes	note	VBZ
cord-320092-0qnvydux	74	10	that	that	IN
cord-320092-0qnvydux	74	11	"	"	``
cord-320092-0qnvydux	74	12	although	although	IN
cord-320092-0qnvydux	74	13	the	the	DT
cord-320092-0qnvydux	74	14	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	74	15	molecule	molecule	NN
cord-320092-0qnvydux	74	16	does	do	VBZ
cord-320092-0qnvydux	74	17	itself	-PRON-	PRP
cord-320092-0qnvydux	74	18	possess	possess	VB
cord-320092-0qnvydux	74	19	some	some	DT
cord-320092-0qnvydux	74	20	antimicrobial	antimicrobial	JJ
cord-320092-0qnvydux	74	21	activity	activity	NN
cord-320092-0qnvydux	74	22	,	,	,
cord-320092-0qnvydux	74	23	this	this	DT
cord-320092-0qnvydux	74	24	is	be	VBZ
cord-320092-0qnvydux	74	25	rather	rather	RB
cord-320092-0qnvydux	74	26	weak	weak	JJ
cord-320092-0qnvydux	74	27	compared	compare	VBN
cord-320092-0qnvydux	74	28	to	to	IN
cord-320092-0qnvydux	74	29	peptides	peptide	NNS
cord-320092-0qnvydux	74	30	such	such	JJ
cord-320092-0qnvydux	74	31	as	as	IN
cord-320092-0qnvydux	74	32	defensins	defensins	NNP
cord-320092-0qnvydux	74	33	,	,	,
cord-320092-0qnvydux	74	34	and	and	CC
cord-320092-0qnvydux	74	35	its	-PRON-	PRP$
cord-320092-0qnvydux	74	36	primary	primary	JJ
cord-320092-0qnvydux	74	37	contribution	contribution	NN
cord-320092-0qnvydux	74	38	to	to	TO
cord-320092-0qnvydux	74	39	innate	innate	JJ
cord-320092-0qnvydux	74	40	immunity	immunity	NN
cord-320092-0qnvydux	74	41	is	be	VBZ
cord-320092-0qnvydux	74	42	via	via	IN
cord-320092-0qnvydux	74	43	regulation	regulation	NN
cord-320092-0qnvydux	74	44	of	of	IN
cord-320092-0qnvydux	74	45	iron	iron	NN
cord-320092-0qnvydux	74	46	"	"	''
cord-320092-0qnvydux	74	47	[	[	-LRB-
cord-320092-0qnvydux	74	48	105	105	CD
cord-320092-0qnvydux	74	49	]	]	-RRB-
cord-320092-0qnvydux	74	50	.	.	.
cord-320092-0qnvydux	75	1	In	in	IN
cord-320092-0qnvydux	75	2	fish	fish	NN
cord-320092-0qnvydux	75	3	species	specie	NNS
cord-320092-0qnvydux	75	4	,	,	,
cord-320092-0qnvydux	75	5	one	one	CD
cord-320092-0qnvydux	75	6	of	of	IN
cord-320092-0qnvydux	75	7	the	the	DT
cord-320092-0qnvydux	75	8	two	two	CD
cord-320092-0qnvydux	75	9	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	75	10	paralogs	paralogs	NNP
cord-320092-0qnvydux	75	11	has	have	VBZ
cord-320092-0qnvydux	75	12	been	be	VBN
cord-320092-0qnvydux	75	13	shown	show	VBN
cord-320092-0qnvydux	75	14	to	to	TO
cord-320092-0qnvydux	75	15	potentially	potentially	RB
cord-320092-0qnvydux	75	16	possess	possess	VB
cord-320092-0qnvydux	75	17	antimicrobial	antimicrobial	JJ
cord-320092-0qnvydux	75	18	effects	effect	NNS
cord-320092-0qnvydux	75	19	in	in	IN
cord-320092-0qnvydux	75	20	innate	innate	JJ
cord-320092-0qnvydux	75	21	immunity	immunity	NN
cord-320092-0qnvydux	75	22	[	[	-LRB-
cord-320092-0qnvydux	75	23	78	78	CD
cord-320092-0qnvydux	75	24	,	,	,
cord-320092-0qnvydux	75	25	79	79	CD
cord-320092-0qnvydux	75	26	]	]	-RRB-
cord-320092-0qnvydux	75	27	.	.	.
cord-320092-0qnvydux	76	1	Finally	finally	RB
cord-320092-0qnvydux	76	2	,	,	,
cord-320092-0qnvydux	76	3	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	76	4	binds	bind	VBZ
cord-320092-0qnvydux	76	5	to	to	IN
cord-320092-0qnvydux	76	6	and	and	CC
cord-320092-0qnvydux	76	7	mediates	mediate	VBZ
cord-320092-0qnvydux	76	8	the	the	DT
cord-320092-0qnvydux	76	9	degradation	degradation	NN
cord-320092-0qnvydux	76	10	of	of	IN
cord-320092-0qnvydux	76	11	ferroportin	ferroportin	NN
cord-320092-0qnvydux	76	12	(	(	-LRB-
cord-320092-0qnvydux	76	13	encoded	encode	VBN
cord-320092-0qnvydux	76	14	by	by	IN
cord-320092-0qnvydux	76	15	the	the	DT
cord-320092-0qnvydux	76	16	SLC40A1	SLC40A1	NNP
cord-320092-0qnvydux	76	17	/	/	SYM
cord-320092-0qnvydux	76	18	FPN1	FPN1	NNP
cord-320092-0qnvydux	76	19	gene	gene	NN
cord-320092-0qnvydux	76	20	)	)	-RRB-
cord-320092-0qnvydux	76	21	,	,	,
cord-320092-0qnvydux	76	22	the	the	DT
cord-320092-0qnvydux	76	23	only	only	RB
cord-320092-0qnvydux	76	24	known	know	VBN
cord-320092-0qnvydux	76	25	cellular	cellular	JJ
cord-320092-0qnvydux	76	26	iron	iron	NN
cord-320092-0qnvydux	76	27	exporter	exporter	NN
cord-320092-0qnvydux	76	28	.	.	.
cord-320092-0qnvydux	77	1	The	the	DT
cord-320092-0qnvydux	77	2	structural	structural	JJ
cord-320092-0qnvydux	77	3	details	detail	NNS
cord-320092-0qnvydux	77	4	of	of	IN
cord-320092-0qnvydux	77	5	this	this	DT
cord-320092-0qnvydux	77	6	interaction	interaction	NN
cord-320092-0qnvydux	77	7	are	be	VBP
cord-320092-0qnvydux	77	8	being	be	VBG
cord-320092-0qnvydux	77	9	mapped	map	VBN
cord-320092-0qnvydux	77	10	and	and	CC
cord-320092-0qnvydux	77	11	studied	study	VBN
cord-320092-0qnvydux	77	12	in	in	IN
cord-320092-0qnvydux	77	13	ever	ever	RB
cord-320092-0qnvydux	77	14	more	more	JJR
cord-320092-0qnvydux	77	15	detail	detail	NN
cord-320092-0qnvydux	77	16	[	[	-LRB-
cord-320092-0qnvydux	77	17	18	18	CD
cord-320092-0qnvydux	77	18	,	,	,
cord-320092-0qnvydux	77	19	88	88	CD
cord-320092-0qnvydux	77	20	,	,	,
cord-320092-0qnvydux	77	21	108	108	CD
cord-320092-0qnvydux	77	22	]	]	-RRB-
cord-320092-0qnvydux	77	23	.	.	.
cord-320092-0qnvydux	78	1	There	there	EX
cord-320092-0qnvydux	78	2	are	be	VBP
cord-320092-0qnvydux	78	3	a	a	DT
cord-320092-0qnvydux	78	4	number	number	NN
cord-320092-0qnvydux	78	5	of	of	IN
cord-320092-0qnvydux	78	6	solved	solve	VBN
cord-320092-0qnvydux	78	7	structures	structure	NNS
cord-320092-0qnvydux	78	8	of	of	IN
cord-320092-0qnvydux	78	9	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	78	10	[	[	-LRB-
cord-320092-0qnvydux	78	11	65	65	CD
cord-320092-0qnvydux	78	12	,	,	,
cord-320092-0qnvydux	78	13	72	72	CD
cord-320092-0qnvydux	78	14	]	]	-RRB-
cord-320092-0qnvydux	78	15	.	.	.
cord-320092-0qnvydux	79	1	An	an	DT
cord-320092-0qnvydux	79	2	NMR	NMR	NNP
cord-320092-0qnvydux	79	3	structure	structure	NN
cord-320092-0qnvydux	79	4	of	of	IN
cord-320092-0qnvydux	79	5	human	human	JJ
cord-320092-0qnvydux	79	6	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	79	7	is	be	VBZ
cord-320092-0qnvydux	79	8	depicted	depict	VBN
cord-320092-0qnvydux	79	9	in	in	IN
cord-320092-0qnvydux	79	10	Fig	Fig	NNP
cord-320092-0qnvydux	79	11	.	.	.
cord-320092-0qnvydux	80	1	1b	1b	LS
cord-320092-0qnvydux	80	2	(	(	-LRB-
cord-320092-0qnvydux	80	3	visualized	visualize	VBN
cord-320092-0qnvydux	80	4	using	use	VBG
cord-320092-0qnvydux	80	5	3-D	3-D	NNP
cord-320092-0qnvydux	80	6	Molecule	Molecule	NNP
cord-320092-0qnvydux	80	7	Viewer	Viewer	NNP
cord-320092-0qnvydux	80	8	,	,	,
cord-320092-0qnvydux	80	9	Vector	Vector	NNP
cord-320092-0qnvydux	80	10	NTI	NTI	NNP
cord-320092-0qnvydux	80	11	Advance	Advance	NNP
cord-320092-0qnvydux	80	12	11.0	11.0	CD
cord-320092-0qnvydux	80	13	,	,	,
cord-320092-0qnvydux	80	14	Invitrogen	Invitrogen	NNP
cord-320092-0qnvydux	80	15	)	)	-RRB-
cord-320092-0qnvydux	80	16	including	include	VBG
cord-320092-0qnvydux	80	17	the	the	DT
cord-320092-0qnvydux	80	18	locations	location	NNS
cord-320092-0qnvydux	80	19	of	of	IN
cord-320092-0qnvydux	80	20	the	the	DT
cord-320092-0qnvydux	80	21	four	four	CD
cord-320092-0qnvydux	80	22	putative	putative	JJ
cord-320092-0qnvydux	80	23	disulfide	disulfide	JJ
cord-320092-0qnvydux	80	24	bonds	bond	NNS
cord-320092-0qnvydux	80	25	.	.	.
cord-320092-0qnvydux	81	1	Of	of	IN
cord-320092-0qnvydux	81	2	note	note	VB
cord-320092-0qnvydux	81	3	,	,	,
cord-320092-0qnvydux	81	4	in	in	IN
cord-320092-0qnvydux	81	5	addition	addition	NN
cord-320092-0qnvydux	81	6	to	to	IN
cord-320092-0qnvydux	81	7	various	various	JJ
cord-320092-0qnvydux	81	8	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	81	9	orthologs	ortholog	NNS
cord-320092-0qnvydux	81	10	containing	contain	VBG
cord-320092-0qnvydux	81	11	eight	eight	CD
cord-320092-0qnvydux	81	12	cysteines	cysteine	NNS
cord-320092-0qnvydux	81	13	,	,	,
cord-320092-0qnvydux	81	14	four	four	CD
cord-320092-0qnvydux	81	15	-	-	HYPH
cord-320092-0qnvydux	81	16	cysteine	cysteine	NN
cord-320092-0qnvydux	81	17	variants	variant	NNS
cord-320092-0qnvydux	81	18	have	have	VBP
cord-320092-0qnvydux	81	19	been	be	VBN
cord-320092-0qnvydux	81	20	described	describe	VBN
cord-320092-0qnvydux	81	21	in	in	IN
cord-320092-0qnvydux	81	22	notothenioid	notothenioid	JJ
cord-320092-0qnvydux	81	23	fish	fish	NN
cord-320092-0qnvydux	81	24	species	specie	NNS
cord-320092-0qnvydux	81	25	[	[	-LRB-
cord-320092-0qnvydux	81	26	137	137	CD
cord-320092-0qnvydux	81	27	]	]	-RRB-
cord-320092-0qnvydux	81	28	.	.	.
cord-320092-0qnvydux	82	1	Available	available	JJ
cord-320092-0qnvydux	82	2	solved	solve	VBN
cord-320092-0qnvydux	82	3	structures	structure	NNS
cord-320092-0qnvydux	82	4	of	of	IN
cord-320092-0qnvydux	82	5	the	the	DT
cord-320092-0qnvydux	82	6	coronavirus	coronavirus	NN
cord-320092-0qnvydux	82	7	spike	spike	NN
cord-320092-0qnvydux	82	8	glycoprotein	glycoprotein	NN
cord-320092-0qnvydux	82	9	,	,	,
cord-320092-0qnvydux	82	10	as	as	RB
cord-320092-0qnvydux	82	11	far	far	RB
cord-320092-0qnvydux	82	12	as	as	IN
cord-320092-0qnvydux	82	13	our	-PRON-	PRP$
cord-320092-0qnvydux	82	14	search	search	NN
cord-320092-0qnvydux	82	15	could	could	MD
cord-320092-0qnvydux	82	16	reveal	reveal	VB
cord-320092-0qnvydux	82	17	,	,	,
cord-320092-0qnvydux	82	18	mostly	mostly	RB
cord-320092-0qnvydux	82	19	utilize	utilize	VB
cord-320092-0qnvydux	82	20	expression	expression	NN
cord-320092-0qnvydux	82	21	constructs	construct	NNS
cord-320092-0qnvydux	82	22	that	that	WDT
cord-320092-0qnvydux	82	23	stop	stop	VBP
cord-320092-0qnvydux	82	24	just	just	RB
cord-320092-0qnvydux	82	25	short	short	RB
cord-320092-0qnvydux	82	26	of	of	IN
cord-320092-0qnvydux	82	27	the	the	DT
cord-320092-0qnvydux	82	28	TM	TM	NNP
cord-320092-0qnvydux	82	29	domain	domain	NN
cord-320092-0qnvydux	82	30	.	.	.
cord-320092-0qnvydux	83	1	As	as	IN
cord-320092-0qnvydux	83	2	noted	note	VBN
cord-320092-0qnvydux	83	3	,	,	,
cord-320092-0qnvydux	83	4	this	this	DT
cord-320092-0qnvydux	83	5	is	be	VBZ
cord-320092-0qnvydux	83	6	partly	partly	RB
cord-320092-0qnvydux	83	7	because	because	IN
cord-320092-0qnvydux	83	8	the	the	DT
cord-320092-0qnvydux	83	9	protein	protein	NN
cord-320092-0qnvydux	83	10	's	's	POS
cord-320092-0qnvydux	83	11	ectodomain	ectodomain	NN
cord-320092-0qnvydux	83	12	is	be	VBZ
cord-320092-0qnvydux	83	13	the	the	DT
cord-320092-0qnvydux	83	14	main	main	JJ
cord-320092-0qnvydux	83	15	focus	focus	NN
cord-320092-0qnvydux	83	16	of	of	IN
cord-320092-0qnvydux	83	17	studies	study	NNS
cord-320092-0qnvydux	83	18	on	on	IN
cord-320092-0qnvydux	83	19	viral	viral	JJ
cord-320092-0qnvydux	83	20	binding	binding	NN
cord-320092-0qnvydux	83	21	to	to	IN
cord-320092-0qnvydux	83	22	host	host	NN
cord-320092-0qnvydux	83	23	surface	surface	NN
cord-320092-0qnvydux	83	24	receptors	receptor	NNS
cord-320092-0qnvydux	83	25	[	[	-LRB-
cord-320092-0qnvydux	83	26	129	129	CD
cord-320092-0qnvydux	83	27	,	,	,
cord-320092-0qnvydux	83	28	131	131	CD
cord-320092-0qnvydux	83	29	,	,	,
cord-320092-0qnvydux	83	30	132	132	CD
cord-320092-0qnvydux	83	31	]	]	-RRB-
cord-320092-0qnvydux	83	32	.	.	.
cord-320092-0qnvydux	84	1	For	for	IN
cord-320092-0qnvydux	84	2	example	example	NN
cord-320092-0qnvydux	84	3	,	,	,
cord-320092-0qnvydux	84	4	Wrapp	Wrapp	NNP
cord-320092-0qnvydux	84	5	,	,	,
cord-320092-0qnvydux	84	6	Wang	Wang	NNP
cord-320092-0qnvydux	84	7	and	and	CC
cord-320092-0qnvydux	84	8	colleagues	colleague	NNS
cord-320092-0qnvydux	84	9	have	have	VBP
cord-320092-0qnvydux	84	10	reported	report	VBN
cord-320092-0qnvydux	84	11	the	the	DT
cord-320092-0qnvydux	84	12	cryo	cryo	NN
cord-320092-0qnvydux	84	13	-	-	HYPH
cord-320092-0qnvydux	84	14	electron	electron	NN
cord-320092-0qnvydux	84	15	microscopy	microscopy	NN
cord-320092-0qnvydux	84	16	structure	structure	NN
cord-320092-0qnvydux	84	17	of	of	IN
cord-320092-0qnvydux	84	18	ectodomain	ectodomain	NNP
cord-320092-0qnvydux	84	19	residues	residue	NNS
cord-320092-0qnvydux	84	20	1	1	CD
cord-320092-0qnvydux	84	21	-	-	HYPH
cord-320092-0qnvydux	84	22	1208	1208	CD
cord-320092-0qnvydux	84	23	of	of	IN
cord-320092-0qnvydux	84	24	the	the	DT
cord-320092-0qnvydux	84	25	spike	spike	NN
cord-320092-0qnvydux	84	26	protein	protein	NN
cord-320092-0qnvydux	84	27	(	(	-LRB-
cord-320092-0qnvydux	84	28	trimer	trimer	NN
cord-320092-0qnvydux	84	29	in	in	IN
cord-320092-0qnvydux	84	30	the	the	DT
cord-320092-0qnvydux	84	31	prefusion	prefusion	NN
cord-320092-0qnvydux	84	32	conformation	conformation	NN
cord-320092-0qnvydux	84	33	)	)	-RRB-
cord-320092-0qnvydux	84	34	[	[	-LRB-
cord-320092-0qnvydux	84	35	132	132	CD
cord-320092-0qnvydux	84	36	]	]	-RRB-
cord-320092-0qnvydux	84	37	,	,	,
cord-320092-0qnvydux	84	38	but	but	CC
cord-320092-0qnvydux	84	39	this	this	DT
cord-320092-0qnvydux	84	40	excludes	exclude	VBZ
cord-320092-0qnvydux	84	41	the	the	DT
cord-320092-0qnvydux	84	42	TM	TM	NNP
cord-320092-0qnvydux	84	43	and	and	CC
cord-320092-0qnvydux	84	44	CT	CT	NNP
cord-320092-0qnvydux	84	45	domains	domain	NNS
cord-320092-0qnvydux	84	46	.	.	.
cord-320092-0qnvydux	85	1	It	-PRON-	PRP
cord-320092-0qnvydux	85	2	goes	go	VBZ
cord-320092-0qnvydux	85	3	without	without	IN
cord-320092-0qnvydux	85	4	saying	say	VBG
cord-320092-0qnvydux	85	5	that	that	IN
cord-320092-0qnvydux	85	6	the	the	DT
cord-320092-0qnvydux	85	7	inclusion	inclusion	NN
cord-320092-0qnvydux	85	8	of	of	IN
cord-320092-0qnvydux	85	9	transmembrane	transmembrane	NN
cord-320092-0qnvydux	85	10	domains	domain	NNS
cord-320092-0qnvydux	85	11	would	would	MD
cord-320092-0qnvydux	85	12	require	require	VB
cord-320092-0qnvydux	85	13	complicated	complicated	JJ
cord-320092-0qnvydux	85	14	structural	structural	JJ
cord-320092-0qnvydux	85	15	elucidation	elucidation	NN
cord-320092-0qnvydux	85	16	protocols	protocol	NNS
cord-320092-0qnvydux	85	17	,	,	,
cord-320092-0qnvydux	85	18	and	and	CC
cord-320092-0qnvydux	85	19	even	even	RB
cord-320092-0qnvydux	85	20	then	then	RB
cord-320092-0qnvydux	85	21	,	,	,
cord-320092-0qnvydux	85	22	one	one	PRP
cord-320092-0qnvydux	85	23	may	may	MD
cord-320092-0qnvydux	85	24	still	still	RB
cord-320092-0qnvydux	85	25	not	not	RB
cord-320092-0qnvydux	85	26	be	be	VB
cord-320092-0qnvydux	85	27	able	able	JJ
cord-320092-0qnvydux	85	28	to	to	TO
cord-320092-0qnvydux	85	29	solve	solve	VB
cord-320092-0qnvydux	85	30	the	the	DT
cord-320092-0qnvydux	85	31	structure	structure	NN
cord-320092-0qnvydux	85	32	of	of	IN
cord-320092-0qnvydux	85	33	the	the	DT
cord-320092-0qnvydux	85	34	protein	protein	NN
cord-320092-0qnvydux	85	35	in	in	IN
cord-320092-0qnvydux	85	36	its	-PRON-	PRP$
cord-320092-0qnvydux	85	37	entirety	entirety	NN
cord-320092-0qnvydux	85	38	.	.	.
cord-320092-0qnvydux	86	1	Moreover	moreover	RB
cord-320092-0qnvydux	86	2	,	,	,
cord-320092-0qnvydux	86	3	we	-PRON-	PRP
cord-320092-0qnvydux	86	4	would	would	MD
cord-320092-0qnvydux	86	5	like	like	VB
cord-320092-0qnvydux	86	6	to	to	TO
cord-320092-0qnvydux	86	7	note	note	VB
cord-320092-0qnvydux	86	8	that	that	IN
cord-320092-0qnvydux	86	9	using	use	VBG
cord-320092-0qnvydux	86	10	the	the	DT
cord-320092-0qnvydux	86	11	Pfam	Pfam	NNP
cord-320092-0qnvydux	86	12	-	-	HYPH
cord-320092-0qnvydux	86	13	A	A	NNP
cord-320092-0qnvydux	86	14	(	(	-LRB-
cord-320092-0qnvydux	86	15	ver	ver	NN
cord-320092-0qnvydux	86	16	.	.	.
cord-320092-0qnvydux	86	17	32	32	CD
cord-320092-0qnvydux	86	18	)	)	-RRB-
cord-320092-0qnvydux	86	19	structural	structural	JJ
cord-320092-0qnvydux	86	20	/	/	SYM
cord-320092-0qnvydux	86	21	domain	domain	NN
cord-320092-0qnvydux	86	22	database	database	NN
cord-320092-0qnvydux	86	23	[	[	-LRB-
cord-320092-0qnvydux	86	24	46	46	CD
cord-320092-0qnvydux	86	25	]	]	-RRB-
cord-320092-0qnvydux	86	26	in	in	IN
cord-320092-0qnvydux	86	27	the	the	DT
cord-320092-0qnvydux	86	28	HHpred	hhpred	JJ
cord-320092-0qnvydux	86	29	remote	remote	JJ
cord-320092-0qnvydux	86	30	homology	homology	NN
cord-320092-0qnvydux	86	31	and	and	CC
cord-320092-0qnvydux	86	32	structure	structure	NN
cord-320092-0qnvydux	86	33	prediction	prediction	NN
cord-320092-0qnvydux	86	34	toolkit	toolkit	NN
cord-320092-0qnvydux	86	35	[	[	-LRB-
cord-320092-0qnvydux	86	36	145	145	CD
cord-320092-0qnvydux	86	37	]	]	-RRB-
cord-320092-0qnvydux	86	38	,	,	,
cord-320092-0qnvydux	86	39	the	the	DT
cord-320092-0qnvydux	86	40	coronavirus	coronavirus	NN
cord-320092-0qnvydux	86	41	spike	spike	NN
cord-320092-0qnvydux	86	42	protein	protein	NN
cord-320092-0qnvydux	86	43	regions	region	NNS
cord-320092-0qnvydux	86	44	analyzed	analyze	VBN
cord-320092-0qnvydux	86	45	here	here	RB
cord-320092-0qnvydux	86	46	show	show	VBP
cord-320092-0qnvydux	86	47	some	some	DT
cord-320092-0qnvydux	86	48	predicted	predict	VBN
cord-320092-0qnvydux	86	49	structural	structural	JJ
cord-320092-0qnvydux	86	50	similarity	similarity	NN
cord-320092-0qnvydux	86	51	to	to	IN
cord-320092-0qnvydux	86	52	lipolysis	lipolysis	NN
cord-320092-0qnvydux	86	53	-	-	HYPH
cord-320092-0qnvydux	86	54	stimulated	stimulate	VBN
cord-320092-0qnvydux	86	55	receptor	receptor	NN
cord-320092-0qnvydux	86	56	(	(	-LRB-
cord-320092-0qnvydux	86	57	LSR	LSR	NNP
cord-320092-0qnvydux	86	58	)	)	-RRB-
cord-320092-0qnvydux	86	59	lipoprotein	lipoprotein	NNP
cord-320092-0qnvydux	86	60	receptor	receptor	NN
cord-320092-0qnvydux	86	61	family	family	NN
cord-320092-0qnvydux	86	62	(	(	-LRB-
cord-320092-0qnvydux	86	63	PF05624	pf05624	NN
cord-320092-0qnvydux	86	64	)	)	-RRB-
cord-320092-0qnvydux	86	65	[	[	-LRB-
cord-320092-0qnvydux	86	66	139	139	CD
cord-320092-0qnvydux	86	67	]	]	-RRB-
cord-320092-0qnvydux	86	68	,	,	,
cord-320092-0qnvydux	86	69	and	and	CC
cord-320092-0qnvydux	86	70	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	86	71	sequences	sequence	NNS
cord-320092-0qnvydux	86	72	show	show	VBP
cord-320092-0qnvydux	86	73	some	some	DT
cord-320092-0qnvydux	86	74	predicted	predict	VBN
cord-320092-0qnvydux	86	75	structural	structural	JJ
cord-320092-0qnvydux	86	76	similarity	similarity	NN
cord-320092-0qnvydux	86	77	to	to	IN
cord-320092-0qnvydux	86	78	the	the	DT
cord-320092-0qnvydux	86	79	Sar8.2	sar8.2	JJ
cord-320092-0qnvydux	86	80	protein	protein	NN
cord-320092-0qnvydux	86	81	family	family	NN
cord-320092-0qnvydux	86	82	found	find	VBD
cord-320092-0qnvydux	86	83	in	in	IN
cord-320092-0qnvydux	86	84	Solanaceae	Solanaceae	NNP
cord-320092-0qnvydux	86	85	plants	plant	NNS
cord-320092-0qnvydux	86	86	(	(	-LRB-
cord-320092-0qnvydux	86	87	PF03058	pf03058	NN
cord-320092-0qnvydux	86	88	)	)	-RRB-
cord-320092-0qnvydux	86	89	[	[	-LRB-
cord-320092-0qnvydux	86	90	2	2	CD
cord-320092-0qnvydux	86	91	]	]	-RRB-
cord-320092-0qnvydux	86	92	.	.	.
cord-320092-0qnvydux	87	1	What	what	WP
cord-320092-0qnvydux	87	2	,	,	,
cord-320092-0qnvydux	87	3	if	if	IN
cord-320092-0qnvydux	87	4	any	any	DT
cord-320092-0qnvydux	87	5	,	,	,
cord-320092-0qnvydux	87	6	significance	significance	VB
cord-320092-0qnvydux	87	7	these	these	DT
cord-320092-0qnvydux	87	8	findings	finding	NNS
cord-320092-0qnvydux	87	9	may	may	MD
cord-320092-0qnvydux	87	10	hold	hold	VB
cord-320092-0qnvydux	87	11	is	be	VBZ
cord-320092-0qnvydux	87	12	unclear	unclear	JJ
cord-320092-0qnvydux	87	13	at	at	IN
cord-320092-0qnvydux	87	14	present	present	JJ
cord-320092-0qnvydux	87	15	.	.	.
cord-320092-0qnvydux	88	1	Of	of	IN
cord-320092-0qnvydux	88	2	more	more	JJR
cord-320092-0qnvydux	88	3	importance	importance	NN
cord-320092-0qnvydux	88	4	right	right	RB
cord-320092-0qnvydux	88	5	now	now	RB
cord-320092-0qnvydux	88	6	would	would	MD
cord-320092-0qnvydux	88	7	be	be	VB
cord-320092-0qnvydux	88	8	the	the	DT
cord-320092-0qnvydux	88	9	theoretical	theoretical	JJ
cord-320092-0qnvydux	88	10	and/or	and/or	CC
cord-320092-0qnvydux	88	11	actual	actual	JJ
cord-320092-0qnvydux	88	12	elucidation	elucidation	NN
cord-320092-0qnvydux	88	13	of	of	IN
cord-320092-0qnvydux	88	14	the	the	DT
cord-320092-0qnvydux	88	15	structure	structure	NN
cord-320092-0qnvydux	88	16	of	of	IN
cord-320092-0qnvydux	88	17	the	the	DT
cord-320092-0qnvydux	88	18	spike	spike	NN
cord-320092-0qnvydux	88	19	protein	protein	NN
cord-320092-0qnvydux	88	20	TM	TM	NNP
cord-320092-0qnvydux	88	21	-	-	HYPH
cord-320092-0qnvydux	88	22	CT	CT	NNP
cord-320092-0qnvydux	88	23	junction	junction	NN
cord-320092-0qnvydux	88	24	region	region	NN
cord-320092-0qnvydux	88	25	and	and	CC
cord-320092-0qnvydux	88	26	a	a	DT
cord-320092-0qnvydux	88	27	comparison	comparison	NN
cord-320092-0qnvydux	88	28	with	with	IN
cord-320092-0qnvydux	88	29	the	the	DT
cord-320092-0qnvydux	88	30	available	available	JJ
cord-320092-0qnvydux	88	31	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	88	32	structures	structure	NNS
cord-320092-0qnvydux	88	33	(	(	-LRB-
cord-320092-0qnvydux	88	34	the	the	DT
cord-320092-0qnvydux	88	35	Pfam	Pfam	NNP
cord-320092-0qnvydux	88	36	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	88	37	entry	entry	NN
cord-320092-0qnvydux	88	38	,	,	,
cord-320092-0qnvydux	88	39	PF06446	PF06446	NNS
cord-320092-0qnvydux	88	40	,	,	,
cord-320092-0qnvydux	88	41	currently	currently	RB
cord-320092-0qnvydux	88	42	references	reference	VBZ
cord-320092-0qnvydux	88	43	six	six	CD
cord-320092-0qnvydux	88	44	PDB	PDB	NNP
cord-320092-0qnvydux	88	45	structures	structure	NNS
cord-320092-0qnvydux	88	46	)	)	-RRB-
cord-320092-0qnvydux	88	47	.	.	.
cord-320092-0qnvydux	89	1	Of	of	IN
cord-320092-0qnvydux	89	2	note	note	NN
cord-320092-0qnvydux	89	3	,	,	,
cord-320092-0qnvydux	89	4	a	a	DT
cord-320092-0qnvydux	89	5	recent	recent	JJ
cord-320092-0qnvydux	89	6	in	in	IN
cord-320092-0qnvydux	89	7	silico	silico	NN
cord-320092-0qnvydux	89	8	study	study	NN
cord-320092-0qnvydux	89	9	has	have	VBZ
cord-320092-0qnvydux	89	10	reported	report	VBN
cord-320092-0qnvydux	89	11	on	on	IN
cord-320092-0qnvydux	89	12	a	a	DT
cord-320092-0qnvydux	89	13	predicted	predict	VBN
cord-320092-0qnvydux	89	14	structural	structural	JJ
cord-320092-0qnvydux	89	15	similarity	similarity	NN
cord-320092-0qnvydux	89	16	and	and	CC
cord-320092-0qnvydux	89	17	compatibility	compatibility	NN
cord-320092-0qnvydux	89	18	between	between	IN
cord-320092-0qnvydux	89	19	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	89	20	and	and	CC
cord-320092-0qnvydux	89	21	an	an	DT
cord-320092-0qnvydux	89	22	allosteric	allosteric	JJ
cord-320092-0qnvydux	89	23	site	site	NN
cord-320092-0qnvydux	89	24	in	in	IN
cord-320092-0qnvydux	89	25	the	the	DT
cord-320092-0qnvydux	89	26	SARS	SARS	NNP
cord-320092-0qnvydux	89	27	-	-	HYPH
cord-320092-0qnvydux	89	28	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	89	29	spike	spike	NN
cord-320092-0qnvydux	89	30	protein	protein	NN
cord-320092-0qnvydux	89	31	[	[	-LRB-
cord-320092-0qnvydux	89	32	32	32	CD
cord-320092-0qnvydux	89	33	]	]	-RRB-
cord-320092-0qnvydux	89	34	.	.	.
cord-320092-0qnvydux	90	1	Given	give	VBN
cord-320092-0qnvydux	90	2	the	the	DT
cord-320092-0qnvydux	90	3	prominence	prominence	NN
cord-320092-0qnvydux	90	4	of	of	IN
cord-320092-0qnvydux	90	5	cysteines	cysteine	NNS
cord-320092-0qnvydux	90	6	in	in	IN
cord-320092-0qnvydux	90	7	the	the	DT
cord-320092-0qnvydux	90	8	aligned	aligned	JJ
cord-320092-0qnvydux	90	9	motif	motif	NN
cord-320092-0qnvydux	90	10	(	(	-LRB-
cord-320092-0qnvydux	90	11	Fig	Fig	NNP
cord-320092-0qnvydux	90	12	.	.	.
cord-320092-0qnvydux	90	13	1a	1a	CD
cord-320092-0qnvydux	90	14	)	)	-RRB-
cord-320092-0qnvydux	90	15	,	,	,
cord-320092-0qnvydux	90	16	how	how	WRB
cord-320092-0qnvydux	90	17	are	be	VBP
cord-320092-0qnvydux	90	18	they	-PRON-	PRP
cord-320092-0qnvydux	90	19	utilized	utilize	VBN
cord-320092-0qnvydux	90	20	in	in	IN
cord-320092-0qnvydux	90	21	the	the	DT
cord-320092-0qnvydux	90	22	respective	respective	JJ
cord-320092-0qnvydux	90	23	similar	similar	JJ
cord-320092-0qnvydux	90	24	domains	domain	NNS
cord-320092-0qnvydux	90	25	?	?	.
cord-320092-0qnvydux	91	1	At	at	IN
cord-320092-0qnvydux	91	2	first	first	JJ
cord-320092-0qnvydux	91	3	pass	pass	NN
cord-320092-0qnvydux	91	4	,	,	,
cord-320092-0qnvydux	91	5	the	the	DT
cord-320092-0qnvydux	91	6	usages	usage	NNS
cord-320092-0qnvydux	91	7	appear	appear	VBP
cord-320092-0qnvydux	91	8	to	to	TO
cord-320092-0qnvydux	91	9	be	be	VB
cord-320092-0qnvydux	91	10	different	different	JJ
cord-320092-0qnvydux	91	11	:	:	:
cord-320092-0qnvydux	91	12	as	as	IN
cord-320092-0qnvydux	91	13	noted	note	VBN
cord-320092-0qnvydux	91	14	earlier	early	RBR
cord-320092-0qnvydux	91	15	,	,	,
cord-320092-0qnvydux	91	16	in	in	IN
cord-320092-0qnvydux	91	17	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	91	18	,	,	,
cord-320092-0qnvydux	91	19	the	the	DT
cord-320092-0qnvydux	91	20	cysteines	cysteine	NNS
cord-320092-0qnvydux	91	21	may	may	MD
cord-320092-0qnvydux	91	22	give	give	VB
cord-320092-0qnvydux	91	23	rise	rise	NN
cord-320092-0qnvydux	91	24	to	to	IN
cord-320092-0qnvydux	91	25	a	a	DT
cord-320092-0qnvydux	91	26	compact	compact	JJ
cord-320092-0qnvydux	91	27	disulfide	disulfide	NN
cord-320092-0qnvydux	91	28	-	-	HYPH
cord-320092-0qnvydux	91	29	bridged	bridge	VBN
cord-320092-0qnvydux	91	30	peptide	peptide	NN
cord-320092-0qnvydux	91	31	[	[	-LRB-
cord-320092-0qnvydux	91	32	65	65	CD
cord-320092-0qnvydux	91	33	,	,	,
cord-320092-0qnvydux	91	34	89	89	CD
cord-320092-0qnvydux	91	35	]	]	-RRB-
cord-320092-0qnvydux	91	36	(	(	-LRB-
cord-320092-0qnvydux	91	37	Fig	fig	NN
cord-320092-0qnvydux	91	38	.	.	.
cord-320092-0qnvydux	91	39	1b	1b	CD
cord-320092-0qnvydux	91	40	)	)	-RRB-
cord-320092-0qnvydux	91	41	,	,	,
cord-320092-0qnvydux	91	42	whereas	whereas	IN
cord-320092-0qnvydux	91	43	in	in	IN
cord-320092-0qnvydux	91	44	coronavirus	coronavirus	NN
cord-320092-0qnvydux	91	45	spike	spike	NN
cord-320092-0qnvydux	91	46	glycoproteins	glycoprotein	NNS
cord-320092-0qnvydux	91	47	,	,	,
cord-320092-0qnvydux	91	48	the	the	DT
cord-320092-0qnvydux	91	49	cysteines	cysteine	NNS
cord-320092-0qnvydux	91	50	in	in	IN
cord-320092-0qnvydux	91	51	the	the	DT
cord-320092-0qnvydux	91	52	TM	TM	NNP
cord-320092-0qnvydux	91	53	-	-	HYPH
cord-320092-0qnvydux	91	54	CT	CT	NNP
cord-320092-0qnvydux	91	55	junction	junction	NN
cord-320092-0qnvydux	91	56	serve	serve	VBP
cord-320092-0qnvydux	91	57	as	as	IN
cord-320092-0qnvydux	91	58	palmitoylation	palmitoylation	NN
cord-320092-0qnvydux	91	59	acceptor	acceptor	NN
cord-320092-0qnvydux	91	60	residues	residue	NNS
cord-320092-0qnvydux	91	61	[	[	-LRB-
cord-320092-0qnvydux	91	62	117	117	CD
cord-320092-0qnvydux	91	63	]	]	-RRB-
cord-320092-0qnvydux	92	1	(	(	-LRB-
cord-320092-0qnvydux	92	2	Fig	Fig	NNP
cord-320092-0qnvydux	92	3	.	.	.
cord-320092-0qnvydux	92	4	1c	1c	LS
cord-320092-0qnvydux	92	5	)	)	-RRB-
cord-320092-0qnvydux	92	6	that	that	WDT
cord-320092-0qnvydux	92	7	facilitate	facilitate	VBP
cord-320092-0qnvydux	92	8	membrane	membrane	NN
cord-320092-0qnvydux	92	9	fusion	fusion	NN
cord-320092-0qnvydux	92	10	[	[	-LRB-
cord-320092-0qnvydux	92	11	24	24	CD
cord-320092-0qnvydux	92	12	]	]	-RRB-
cord-320092-0qnvydux	92	13	.	.	.
cord-320092-0qnvydux	93	1	It	-PRON-	PRP
cord-320092-0qnvydux	93	2	should	should	MD
cord-320092-0qnvydux	93	3	be	be	VB
cord-320092-0qnvydux	93	4	mentioned	mention	VBN
cord-320092-0qnvydux	93	5	,	,	,
cord-320092-0qnvydux	93	6	however	however	RB
cord-320092-0qnvydux	93	7	,	,	,
cord-320092-0qnvydux	94	1	that	that	IN
cord-320092-0qnvydux	94	2	'	'	``
cord-320092-0qnvydux	94	3	mini	mini	JJ
cord-320092-0qnvydux	94	4	-	-	HYPH
cord-320092-0qnvydux	94	5	hepcidins	hepcidins	JJ
cord-320092-0qnvydux	94	6	'	'	POS
cord-320092-0qnvydux	94	7	conjugated	conjugate	VBN
cord-320092-0qnvydux	94	8	to	to	IN
cord-320092-0qnvydux	94	9	palmitoyl	palmitoyl	NNP
cord-320092-0qnvydux	94	10	groups	group	NNS
cord-320092-0qnvydux	94	11	have	have	VBP
cord-320092-0qnvydux	94	12	been	be	VBN
cord-320092-0qnvydux	94	13	synthesized	synthesize	VBN
cord-320092-0qnvydux	94	14	and	and	CC
cord-320092-0qnvydux	94	15	studied	study	VBN
cord-320092-0qnvydux	94	16	previously	previously	RB
cord-320092-0qnvydux	94	17	[	[	-LRB-
cord-320092-0qnvydux	94	18	106	106	CD
cord-320092-0qnvydux	94	19	]	]	-RRB-
cord-320092-0qnvydux	94	20	,	,	,
cord-320092-0qnvydux	94	21	but	but	CC
cord-320092-0qnvydux	94	22	these	these	DT
cord-320092-0qnvydux	94	23	do	do	VBP
cord-320092-0qnvydux	94	24	not	not	RB
cord-320092-0qnvydux	94	25	occur	occur	VB
cord-320092-0qnvydux	94	26	naturally	naturally	RB
cord-320092-0qnvydux	94	27	.	.	.
cord-320092-0qnvydux	95	1	As	as	IN
cord-320092-0qnvydux	95	2	for	for	IN
cord-320092-0qnvydux	95	3	the	the	DT
cord-320092-0qnvydux	95	4	SARS	SARS	NNP
cord-320092-0qnvydux	95	5	-	-	HYPH
cord-320092-0qnvydux	95	6	CoV	CoV	NNP
cord-320092-0qnvydux	95	7	,	,	,
cord-320092-0qnvydux	95	8	at	at	IN
cord-320092-0qnvydux	95	9	least	least	JJS
cord-320092-0qnvydux	95	10	a	a	DT
cord-320092-0qnvydux	95	11	portion	portion	NN
cord-320092-0qnvydux	95	12	of	of	IN
cord-320092-0qnvydux	95	13	the	the	DT
cord-320092-0qnvydux	95	14	palmitoylation	palmitoylation	NN
cord-320092-0qnvydux	95	15	of	of	IN
cord-320092-0qnvydux	95	16	the	the	DT
cord-320092-0qnvydux	95	17	spike	spike	NN
cord-320092-0qnvydux	95	18	protein	protein	NN
cord-320092-0qnvydux	95	19	has	have	VBZ
cord-320092-0qnvydux	95	20	been	be	VBN
cord-320092-0qnvydux	95	21	reported	report	VBN
cord-320092-0qnvydux	95	22	to	to	TO
cord-320092-0qnvydux	95	23	occur	occur	VB
cord-320092-0qnvydux	95	24	in	in	IN
cord-320092-0qnvydux	95	25	a	a	DT
cord-320092-0qnvydux	95	26	pre	pre	JJ
cord-320092-0qnvydux	95	27	-	-	JJ
cord-320092-0qnvydux	95	28	medial	medial	JJ
cord-320092-0qnvydux	95	29	Golgi	Golgi	NNP
cord-320092-0qnvydux	95	30	compartment	compartment	NN
cord-320092-0qnvydux	95	31	[	[	-LRB-
cord-320092-0qnvydux	95	32	81	81	CD
cord-320092-0qnvydux	95	33	]	]	-RRB-
cord-320092-0qnvydux	95	34	.	.	.
cord-320092-0qnvydux	96	1	However	however	RB
cord-320092-0qnvydux	96	2	,	,	,
cord-320092-0qnvydux	96	3	there	there	EX
cord-320092-0qnvydux	96	4	is	be	VBZ
cord-320092-0qnvydux	96	5	also	also	RB
cord-320092-0qnvydux	96	6	the	the	DT
cord-320092-0qnvydux	96	7	possibility	possibility	NN
cord-320092-0qnvydux	96	8	of	of	IN
cord-320092-0qnvydux	96	9	crossdisulfide	crossdisulfide	NN
cord-320092-0qnvydux	96	10	bond	bond	NN
cord-320092-0qnvydux	96	11	formation	formation	NN
cord-320092-0qnvydux	96	12	with	with	IN
cord-320092-0qnvydux	96	13	a	a	DT
cord-320092-0qnvydux	96	14	non	non	JJ
cord-320092-0qnvydux	96	15	-	-	JJ
cord-320092-0qnvydux	96	16	homologous	homologous	JJ
cord-320092-0qnvydux	96	17	small	small	JJ
cord-320092-0qnvydux	96	18	cluster	cluster	NN
cord-320092-0qnvydux	96	19	of	of	IN
cord-320092-0qnvydux	96	20	cysteines	cysteine	NNS
cord-320092-0qnvydux	96	21	within	within	IN
cord-320092-0qnvydux	96	22	the	the	DT
cord-320092-0qnvydux	96	23	envelope	envelope	NN
cord-320092-0qnvydux	96	24	protein	protein	NN
cord-320092-0qnvydux	96	25	[	[	-LRB-
cord-320092-0qnvydux	96	26	135	135	CD
cord-320092-0qnvydux	96	27	]	]	-RRB-
cord-320092-0qnvydux	96	28	.	.	.
cord-320092-0qnvydux	97	1	Moreover	moreover	RB
cord-320092-0qnvydux	97	2	,	,	,
cord-320092-0qnvydux	97	3	if	if	IN
cord-320092-0qnvydux	97	4	S	S	NNP
cord-320092-0qnvydux	97	5	-	-	HYPH
cord-320092-0qnvydux	97	6	palmitoylation	palmitoylation	NNP
cord-320092-0qnvydux	97	7	is	be	VBZ
cord-320092-0qnvydux	97	8	a	a	DT
cord-320092-0qnvydux	97	9	reversible	reversible	JJ
cord-320092-0qnvydux	97	10	and	and	CC
cord-320092-0qnvydux	97	11	dynamic	dynamic	JJ
cord-320092-0qnvydux	97	12	process	process	NN
cord-320092-0qnvydux	97	13	[	[	-LRB-
cord-320092-0qnvydux	97	14	118	118	CD
cord-320092-0qnvydux	97	15	]	]	-RRB-
cord-320092-0qnvydux	97	16	,	,	,
cord-320092-0qnvydux	97	17	it	-PRON-	PRP
cord-320092-0qnvydux	97	18	is	be	VBZ
cord-320092-0qnvydux	97	19	to	to	TO
cord-320092-0qnvydux	97	20	be	be	VB
cord-320092-0qnvydux	97	21	determined	determine	VBN
cord-320092-0qnvydux	97	22	if	if	IN
cord-320092-0qnvydux	97	23	the	the	DT
cord-320092-0qnvydux	97	24	spike	spike	NN
cord-320092-0qnvydux	97	25	protein	protein	NN
cord-320092-0qnvydux	97	26	junction	junction	NN
cord-320092-0qnvydux	97	27	cysteines	cysteine	NNS
cord-320092-0qnvydux	97	28	might	may	MD
cord-320092-0qnvydux	97	29	in	in	IN
cord-320092-0qnvydux	97	30	fact	fact	NN
cord-320092-0qnvydux	97	31	have	have	VB
cord-320092-0qnvydux	97	32	a	a	DT
cord-320092-0qnvydux	97	33	different	different	JJ
cord-320092-0qnvydux	97	34	post	post	JJ
cord-320092-0qnvydux	97	35	-	-	JJ
cord-320092-0qnvydux	97	36	translational	translational	JJ
cord-320092-0qnvydux	97	37	modification	modification	NN
cord-320092-0qnvydux	97	38	in	in	IN
cord-320092-0qnvydux	97	39	the	the	DT
cord-320092-0qnvydux	97	40	host	host	NN
cord-320092-0qnvydux	97	41	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	97	42	environment	environment	NN
cord-320092-0qnvydux	97	43	(	(	-LRB-
cord-320092-0qnvydux	97	44	although	although	IN
cord-320092-0qnvydux	97	45	there	there	EX
cord-320092-0qnvydux	97	46	is	be	VBZ
cord-320092-0qnvydux	97	47	no	no	DT
cord-320092-0qnvydux	97	48	evidence	evidence	NN
cord-320092-0qnvydux	97	49	of	of	IN
cord-320092-0qnvydux	97	50	this	this	DT
cord-320092-0qnvydux	97	51	at	at	IN
cord-320092-0qnvydux	97	52	the	the	DT
cord-320092-0qnvydux	97	53	moment	moment	NN
cord-320092-0qnvydux	97	54	,	,	,
cord-320092-0qnvydux	97	55	and	and	CC
cord-320092-0qnvydux	97	56	the	the	DT
cord-320092-0qnvydux	97	57	reversibility	reversibility	NN
cord-320092-0qnvydux	97	58	of	of	IN
cord-320092-0qnvydux	97	59	palmitoylation	palmitoylation	NN
cord-320092-0qnvydux	97	60	in	in	IN
cord-320092-0qnvydux	97	61	viral	viral	JJ
cord-320092-0qnvydux	97	62	spike	spike	NN
cord-320092-0qnvydux	97	63	proteins	protein	NNS
cord-320092-0qnvydux	97	64	has	have	VBZ
cord-320092-0qnvydux	97	65	not	not	RB
cord-320092-0qnvydux	97	66	been	be	VBN
cord-320092-0qnvydux	97	67	reported	report	VBN
cord-320092-0qnvydux	97	68	[	[	-LRB-
cord-320092-0qnvydux	97	69	47	47	CD
cord-320092-0qnvydux	97	70	]	]	-RRB-
cord-320092-0qnvydux	97	71	)	)	-RRB-
cord-320092-0qnvydux	97	72	.	.	.
cord-320092-0qnvydux	98	1	That	that	DT
cord-320092-0qnvydux	98	2	being	be	VBG
cord-320092-0qnvydux	98	3	said	say	VBD
cord-320092-0qnvydux	98	4	,	,	,
cord-320092-0qnvydux	98	5	in	in	IN
cord-320092-0qnvydux	98	6	the	the	DT
cord-320092-0qnvydux	98	7	cited	cite	VBN
cord-320092-0qnvydux	98	8	paper	paper	NN
cord-320092-0qnvydux	98	9	by	by	IN
cord-320092-0qnvydux	98	10	McBride	McBride	NNP
cord-320092-0qnvydux	98	11	and	and	CC
cord-320092-0qnvydux	98	12	Machamer	Machamer	NNP
cord-320092-0qnvydux	98	13	,	,	,
cord-320092-0qnvydux	98	14	the	the	DT
cord-320092-0qnvydux	98	15	authors	author	NNS
cord-320092-0qnvydux	98	16	conclude	conclude	VBP
cord-320092-0qnvydux	98	17	that	that	IN
cord-320092-0qnvydux	98	18	the	the	DT
cord-320092-0qnvydux	98	19	palmitoylation	palmitoylation	NN
cord-320092-0qnvydux	98	20	of	of	IN
cord-320092-0qnvydux	98	21	the	the	DT
cord-320092-0qnvydux	98	22	SARS	SARS	NNP
cord-320092-0qnvydux	98	23	-	-	HYPH
cord-320092-0qnvydux	98	24	CoV	CoV	NNP
cord-320092-0qnvydux	98	25	spike	spike	NN
cord-320092-0qnvydux	98	26	protein	protein	NN
cord-320092-0qnvydux	98	27	"	"	''
cord-320092-0qnvydux	98	28	was	be	VBD
cord-320092-0qnvydux	98	29	not	not	RB
cord-320092-0qnvydux	98	30	necessary	necessary	JJ
cord-320092-0qnvydux	98	31	for	for	IN
cord-320092-0qnvydux	98	32	S	s	NN
cord-320092-0qnvydux	98	33	protein	protein	NN
cord-320092-0qnvydux	98	34	stability	stability	NN
cord-320092-0qnvydux	98	35	,	,	,
cord-320092-0qnvydux	98	36	trafficking	trafficking	NN
cord-320092-0qnvydux	98	37	or	or	CC
cord-320092-0qnvydux	98	38	subcellular	subcellular	JJ
cord-320092-0qnvydux	98	39	localization	localization	NN
cord-320092-0qnvydux	98	40	"	"	''
cord-320092-0qnvydux	98	41	nor	nor	CC
cord-320092-0qnvydux	98	42	"	"	``
cord-320092-0qnvydux	98	43	for	for	IN
cord-320092-0qnvydux	98	44	efficient	efficient	JJ
cord-320092-0qnvydux	98	45	interaction	interaction	NN
cord-320092-0qnvydux	98	46	with	with	IN
cord-320092-0qnvydux	98	47	M	M	NNP
cord-320092-0qnvydux	98	48	protein	protein	NN
cord-320092-0qnvydux	98	49	"	"	''
cord-320092-0qnvydux	98	50	[	[	-LRB-
cord-320092-0qnvydux	98	51	81	81	CD
cord-320092-0qnvydux	98	52	]	]	-RRB-
cord-320092-0qnvydux	98	53	.	.	.
cord-320092-0qnvydux	99	1	To	to	TO
cord-320092-0qnvydux	99	2	what	what	WDT
cord-320092-0qnvydux	99	3	extent	extent	NN
cord-320092-0qnvydux	99	4	the	the	DT
cord-320092-0qnvydux	99	5	post	post	JJ
cord-320092-0qnvydux	99	6	-	-	JJ
cord-320092-0qnvydux	99	7	translational	translational	JJ
cord-320092-0qnvydux	99	8	modifications	modification	NNS
cord-320092-0qnvydux	99	9	of	of	IN
cord-320092-0qnvydux	99	10	the	the	DT
cord-320092-0qnvydux	99	11	spike	spike	NN
cord-320092-0qnvydux	99	12	protein	protein	NN
cord-320092-0qnvydux	99	13	and	and	CC
cord-320092-0qnvydux	99	14	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	99	15	,	,	,
cord-320092-0qnvydux	99	16	be	be	VB
cord-320092-0qnvydux	99	17	it	-PRON-	PRP
cord-320092-0qnvydux	99	18	furin	furin	NN
cord-320092-0qnvydux	99	19	cleavage	cleavage	NN
cord-320092-0qnvydux	99	20	,	,	,
cord-320092-0qnvydux	99	21	disulfide	disulfide	JJ
cord-320092-0qnvydux	99	22	bonds	bond	NNS
cord-320092-0qnvydux	99	23	or	or	CC
cord-320092-0qnvydux	99	24	palmitoylation	palmitoylation	NN
cord-320092-0qnvydux	99	25	,	,	,
cord-320092-0qnvydux	99	26	are	be	VBP
cord-320092-0qnvydux	99	27	in	in	IN
cord-320092-0qnvydux	99	28	any	any	DT
cord-320092-0qnvydux	99	29	way	way	NN
cord-320092-0qnvydux	99	30	similar	similar	JJ
cord-320092-0qnvydux	99	31	in	in	IN
cord-320092-0qnvydux	99	32	an	an	DT
cord-320092-0qnvydux	99	33	intracellular	intracellular	JJ
cord-320092-0qnvydux	99	34	context	context	NN
cord-320092-0qnvydux	99	35	,	,	,
cord-320092-0qnvydux	99	36	remains	remain	VBZ
cord-320092-0qnvydux	99	37	to	to	TO
cord-320092-0qnvydux	99	38	be	be	VB
cord-320092-0qnvydux	99	39	examined	examine	VBN
cord-320092-0qnvydux	99	40	.	.	.
cord-320092-0qnvydux	100	1	As	as	IN
cord-320092-0qnvydux	100	2	alluded	allude	VBN
cord-320092-0qnvydux	100	3	to	to	IN
cord-320092-0qnvydux	100	4	earlier	early	RBR
cord-320092-0qnvydux	100	5	,	,	,
cord-320092-0qnvydux	100	6	in	in	IN
cord-320092-0qnvydux	100	7	terms	term	NNS
cord-320092-0qnvydux	100	8	of	of	IN
cord-320092-0qnvydux	100	9	the	the	DT
cord-320092-0qnvydux	100	10	possibility	possibility	NN
cord-320092-0qnvydux	100	11	of	of	IN
cord-320092-0qnvydux	100	12	an	an	DT
cord-320092-0qnvydux	100	13	evolutionary	evolutionary	JJ
cord-320092-0qnvydux	100	14	connection	connection	NN
cord-320092-0qnvydux	100	15	between	between	IN
cord-320092-0qnvydux	100	16	the	the	DT
cord-320092-0qnvydux	100	17	spike	spike	NN
cord-320092-0qnvydux	100	18	protein	protein	NN
cord-320092-0qnvydux	100	19	and	and	CC
cord-320092-0qnvydux	100	20	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	100	21	,	,	,
cord-320092-0qnvydux	100	22	one	one	PRP
cord-320092-0qnvydux	100	23	could	could	MD
cord-320092-0qnvydux	100	24	imagine	imagine	VB
cord-320092-0qnvydux	100	25	a	a	DT
cord-320092-0qnvydux	100	26	scenario	scenario	NN
cord-320092-0qnvydux	100	27	whereby	whereby	WRB
cord-320092-0qnvydux	100	28	an	an	DT
cord-320092-0qnvydux	100	29	ancestral	ancestral	JJ
cord-320092-0qnvydux	100	30	spike	spike	NN
cord-320092-0qnvydux	100	31	protein	protein	NN
cord-320092-0qnvydux	100	32	acquired	acquire	VBD
cord-320092-0qnvydux	100	33	a	a	DT
cord-320092-0qnvydux	100	34	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	100	35	-	-	HYPH
cord-320092-0qnvydux	100	36	like	like	JJ
cord-320092-0qnvydux	100	37	sequence	sequence	NN
cord-320092-0qnvydux	100	38	from	from	IN
cord-320092-0qnvydux	100	39	a	a	DT
cord-320092-0qnvydux	100	40	host	host	NN
cord-320092-0qnvydux	100	41	organism	organism	NN
cord-320092-0qnvydux	100	42	,	,	,
cord-320092-0qnvydux	100	43	and	and	CC
cord-320092-0qnvydux	100	44	the	the	DT
cord-320092-0qnvydux	100	45	new	new	JJ
cord-320092-0qnvydux	100	46	sequence	sequence	NN
cord-320092-0qnvydux	100	47	was	be	VBD
cord-320092-0qnvydux	100	48	palmitoylated	palmitoylate	VBN
cord-320092-0qnvydux	100	49	to	to	TO
cord-320092-0qnvydux	100	50	aid	aid	VB
cord-320092-0qnvydux	100	51	with	with	IN
cord-320092-0qnvydux	100	52	membrane	membrane	NNP
cord-320092-0qnvydux	100	53	association	association	NNP
cord-320092-0qnvydux	100	54	.	.	.
cord-320092-0qnvydux	101	1	Li	Li	NNP
cord-320092-0qnvydux	101	2	points	point	VBZ
cord-320092-0qnvydux	101	3	out	out	RP
cord-320092-0qnvydux	101	4	that	that	IN
cord-320092-0qnvydux	101	5	"	"	``
cord-320092-0qnvydux	101	6	the	the	DT
cord-320092-0qnvydux	101	7	primordial	primordial	JJ
cord-320092-0qnvydux	101	8	form	form	NN
cord-320092-0qnvydux	101	9	of	of	IN
cord-320092-0qnvydux	101	10	coronavirus	coronavirus	NN
cord-320092-0qnvydux	101	11	spikes	spike	NNS
cord-320092-0qnvydux	101	12	might	may	MD
cord-320092-0qnvydux	101	13	contain	contain	VB
cord-320092-0qnvydux	101	14	S2	S2	NNP
cord-320092-0qnvydux	101	15	only	only	RB
cord-320092-0qnvydux	101	16	"	"	''
cord-320092-0qnvydux	101	17	[	[	-LRB-
cord-320092-0qnvydux	101	18	75	75	CD
cord-320092-0qnvydux	101	19	]	]	-RRB-
cord-320092-0qnvydux	101	20	,	,	,
cord-320092-0qnvydux	101	21	and	and	CC
cord-320092-0qnvydux	101	22	the	the	DT
cord-320092-0qnvydux	101	23	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	101	24	motif	motif	NN
cord-320092-0qnvydux	101	25	features	feature	VBZ
cord-320092-0qnvydux	101	26	highlighted	highlight	VBN
cord-320092-0qnvydux	101	27	in	in	IN
cord-320092-0qnvydux	101	28	the	the	DT
cord-320092-0qnvydux	101	29	current	current	JJ
cord-320092-0qnvydux	101	30	report	report	NN
cord-320092-0qnvydux	101	31	do	do	VBP
cord-320092-0qnvydux	101	32	not	not	RB
cord-320092-0qnvydux	101	33	appear	appear	VB
cord-320092-0qnvydux	101	34	to	to	TO
cord-320092-0qnvydux	101	35	be	be	VB
cord-320092-0qnvydux	101	36	present	present	JJ
cord-320092-0qnvydux	101	37	in	in	IN
cord-320092-0qnvydux	101	38	other	other	JJ
cord-320092-0qnvydux	101	39	class	class	NN
cord-320092-0qnvydux	102	1	I	-PRON-	PRP
cord-320092-0qnvydux	102	2	viral	viral	JJ
cord-320092-0qnvydux	102	3	membrane	membrane	NN
cord-320092-0qnvydux	102	4	fusion	fusion	NN
cord-320092-0qnvydux	102	5	proteins	protein	NNS
cord-320092-0qnvydux	102	6	(	(	-LRB-
cord-320092-0qnvydux	102	7	which	which	WDT
cord-320092-0qnvydux	102	8	include	include	VBP
cord-320092-0qnvydux	102	9	the	the	DT
cord-320092-0qnvydux	102	10	influenza	influenza	NN
cord-320092-0qnvydux	102	11	virus	virus	NN
cord-320092-0qnvydux	102	12	hemagglutinin	hemagglutinin	NNP
cord-320092-0qnvydux	102	13	[	[	-LRB-
cord-320092-0qnvydux	102	14	20	20	CD
cord-320092-0qnvydux	102	15	,	,	,
cord-320092-0qnvydux	102	16	66	66	CD
cord-320092-0qnvydux	102	17	]	]	-RRB-
cord-320092-0qnvydux	102	18	)	)	-RRB-
cord-320092-0qnvydux	102	19	,	,	,
cord-320092-0qnvydux	102	20	although	although	IN
cord-320092-0qnvydux	102	21	we	-PRON-	PRP
cord-320092-0qnvydux	102	22	have	have	VBP
cord-320092-0qnvydux	102	23	not	not	RB
cord-320092-0qnvydux	102	24	performed	perform	VBN
cord-320092-0qnvydux	102	25	an	an	DT
cord-320092-0qnvydux	102	26	exhaustive	exhaustive	JJ
cord-320092-0qnvydux	102	27	search	search	NN
cord-320092-0qnvydux	102	28	.	.	.
cord-320092-0qnvydux	103	1	However	however	RB
cord-320092-0qnvydux	103	2	,	,	,
cord-320092-0qnvydux	103	3	a	a	DT
cord-320092-0qnvydux	103	4	number	number	NN
cord-320092-0qnvydux	103	5	of	of	IN
cord-320092-0qnvydux	103	6	questions	question	NNS
cord-320092-0qnvydux	103	7	might	may	MD
cord-320092-0qnvydux	103	8	then	then	RB
cord-320092-0qnvydux	103	9	arise	arise	VB
cord-320092-0qnvydux	103	10	under	under	IN
cord-320092-0qnvydux	103	11	this	this	DT
cord-320092-0qnvydux	103	12	scenario	scenario	NN
cord-320092-0qnvydux	103	13	,	,	,
cord-320092-0qnvydux	103	14	such	such	JJ
cord-320092-0qnvydux	103	15	as	as	IN
cord-320092-0qnvydux	103	16	the	the	DT
cord-320092-0qnvydux	103	17	difference	difference	NN
cord-320092-0qnvydux	103	18	between	between	IN
cord-320092-0qnvydux	103	19	the	the	DT
cord-320092-0qnvydux	103	20	primary	primary	JJ
cord-320092-0qnvydux	103	21	localizations	localization	NNS
cord-320092-0qnvydux	103	22	of	of	IN
cord-320092-0qnvydux	103	23	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	103	24	(	(	-LRB-
cord-320092-0qnvydux	103	25	considering	consider	VBG
cord-320092-0qnvydux	103	26	its	-PRON-	PRP$
cord-320092-0qnvydux	103	27	putative	putative	JJ
cord-320092-0qnvydux	103	28	interaction	interaction	NN
cord-320092-0qnvydux	103	29	with	with	IN
cord-320092-0qnvydux	103	30	extracellular	extracellular	JJ
cord-320092-0qnvydux	103	31	and	and	CC
cord-320092-0qnvydux	103	32	transmembrane	transmembrane	JJ
cord-320092-0qnvydux	103	33	regions	region	NNS
cord-320092-0qnvydux	103	34	of	of	IN
cord-320092-0qnvydux	103	35	ferroportin	ferroportin	NNP
cord-320092-0qnvydux	103	36	[	[	-LRB-
cord-320092-0qnvydux	103	37	12	12	CD
cord-320092-0qnvydux	103	38	,	,	,
cord-320092-0qnvydux	103	39	18	18	CD
cord-320092-0qnvydux	103	40	,	,	,
cord-320092-0qnvydux	103	41	108	108	CD
cord-320092-0qnvydux	103	42	]	]	-RRB-
cord-320092-0qnvydux	103	43	)	)	-RRB-
cord-320092-0qnvydux	103	44	versus	versus	IN
cord-320092-0qnvydux	103	45	the	the	DT
cord-320092-0qnvydux	103	46	CT	CT	NNP
cord-320092-0qnvydux	103	47	domain	domain	NN
cord-320092-0qnvydux	103	48	of	of	IN
cord-320092-0qnvydux	103	49	the	the	DT
cord-320092-0qnvydux	103	50	spike	spike	NN
cord-320092-0qnvydux	103	51	protein	protein	NN
cord-320092-0qnvydux	103	52	.	.	.
cord-320092-0qnvydux	104	1	Alternatively	alternatively	RB
cord-320092-0qnvydux	104	2	,	,	,
cord-320092-0qnvydux	104	3	it	-PRON-	PRP
cord-320092-0qnvydux	104	4	might	may	MD
cord-320092-0qnvydux	104	5	be	be	VB
cord-320092-0qnvydux	104	6	argued	argue	VBN
cord-320092-0qnvydux	104	7	that	that	IN
cord-320092-0qnvydux	104	8	perhaps	perhaps	RB
cord-320092-0qnvydux	104	9	a	a	DT
cord-320092-0qnvydux	104	10	case	case	NN
cord-320092-0qnvydux	104	11	of	of	IN
cord-320092-0qnvydux	104	12	convergent	convergent	JJ
cord-320092-0qnvydux	104	13	sequence	sequence	NN
cord-320092-0qnvydux	104	14	evolution	evolution	NN
cord-320092-0qnvydux	104	15	is	be	VBZ
cord-320092-0qnvydux	104	16	at	at	IN
cord-320092-0qnvydux	104	17	play	play	NN
cord-320092-0qnvydux	104	18	.	.	.
cord-320092-0qnvydux	105	1	For	for	IN
cord-320092-0qnvydux	105	2	example	example	NN
cord-320092-0qnvydux	105	3	,	,	,
cord-320092-0qnvydux	105	4	the	the	DT
cord-320092-0qnvydux	105	5	influenza	influenza	NN
cord-320092-0qnvydux	105	6	hemagglutinin	hemagglutinin	NN
cord-320092-0qnvydux	105	7	glycoprotein	glycoprotein	NN
cord-320092-0qnvydux	105	8	appears	appear	VBZ
cord-320092-0qnvydux	105	9	to	to	TO
cord-320092-0qnvydux	105	10	have	have	VB
cord-320092-0qnvydux	105	11	a	a	DT
cord-320092-0qnvydux	105	12	conserved	conserve	VBN
cord-320092-0qnvydux	105	13	'	'	``
cord-320092-0qnvydux	105	14	CXICI	CXICI	NNP
cord-320092-0qnvydux	105	15	'	'	''
cord-320092-0qnvydux	105	16	motif	motif	NN
cord-320092-0qnvydux	105	17	in	in	IN
cord-320092-0qnvydux	105	18	its	-PRON-	PRP$
cord-320092-0qnvydux	105	19	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	105	20	tail	tail	NN
cord-320092-0qnvydux	105	21	domain	domain	NN
cord-320092-0qnvydux	105	22	[	[	-LRB-
cord-320092-0qnvydux	105	23	93	93	CD
cord-320092-0qnvydux	105	24	,	,	,
cord-320092-0qnvydux	105	25	128	128	CD
cord-320092-0qnvydux	105	26	]	]	-RRB-
cord-320092-0qnvydux	105	27	,	,	,
cord-320092-0qnvydux	105	28	and	and	CC
cord-320092-0qnvydux	105	29	perhaps	perhaps	RB
cord-320092-0qnvydux	105	30	an	an	DT
cord-320092-0qnvydux	105	31	ancestral	ancestral	JJ
cord-320092-0qnvydux	105	32	spike	spike	NN
cord-320092-0qnvydux	105	33	protein	protein	NN
cord-320092-0qnvydux	105	34	with	with	IN
cord-320092-0qnvydux	105	35	similar	similar	JJ
cord-320092-0qnvydux	105	36	features	feature	NNS
cord-320092-0qnvydux	105	37	convergently	convergently	RB
cord-320092-0qnvydux	105	38	acquired	acquire	VBN
cord-320092-0qnvydux	105	39	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	105	40	-	-	HYPH
cord-320092-0qnvydux	105	41	like	like	JJ
cord-320092-0qnvydux	105	42	sequence	sequence	NN
cord-320092-0qnvydux	105	43	motifs	motif	NNS
cord-320092-0qnvydux	105	44	.	.	.
cord-320092-0qnvydux	106	1	These	these	DT
cord-320092-0qnvydux	106	2	are	be	VBP
cord-320092-0qnvydux	106	3	of	of	IN
cord-320092-0qnvydux	106	4	course	course	NN
cord-320092-0qnvydux	106	5	speculations	speculation	NNS
cord-320092-0qnvydux	106	6	and	and	CC
cord-320092-0qnvydux	106	7	remain	remain	VBP
cord-320092-0qnvydux	106	8	open	open	JJ
cord-320092-0qnvydux	106	9	questions	question	NNS
cord-320092-0qnvydux	106	10	.	.	.
cord-320092-0qnvydux	107	1	Investigations	investigation	NNS
cord-320092-0qnvydux	107	2	pursuing	pursue	VBG
cord-320092-0qnvydux	107	3	these	these	DT
cord-320092-0qnvydux	107	4	topics	topic	NNS
cord-320092-0qnvydux	107	5	could	could	MD
cord-320092-0qnvydux	107	6	also	also	RB
cord-320092-0qnvydux	107	7	make	make	VB
cord-320092-0qnvydux	107	8	use	use	NN
cord-320092-0qnvydux	107	9	of	of	IN
cord-320092-0qnvydux	107	10	studies	study	NNS
cord-320092-0qnvydux	107	11	that	that	WDT
cord-320092-0qnvydux	107	12	attempt	attempt	VBP
cord-320092-0qnvydux	107	13	to	to	TO
cord-320092-0qnvydux	107	14	trace	trace	VB
cord-320092-0qnvydux	107	15	the	the	DT
cord-320092-0qnvydux	107	16	evolutionary	evolutionary	JJ
cord-320092-0qnvydux	107	17	history	history	NN
cord-320092-0qnvydux	107	18	of	of	IN
cord-320092-0qnvydux	107	19	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	107	20	itself	-PRON-	PRP
cord-320092-0qnvydux	107	21	[	[	-LRB-
cord-320092-0qnvydux	107	22	67	67	CD
cord-320092-0qnvydux	107	23	,	,	,
cord-320092-0qnvydux	107	24	137	137	CD
cord-320092-0qnvydux	107	25	]	]	-RRB-
cord-320092-0qnvydux	107	26	.	.	.
cord-320092-0qnvydux	108	1	One	one	CD
cord-320092-0qnvydux	108	2	of	of	IN
cord-320092-0qnvydux	108	3	the	the	DT
cord-320092-0qnvydux	108	4	first	first	JJ
cord-320092-0qnvydux	108	5	questions	question	NNS
cord-320092-0qnvydux	108	6	that	that	WDT
cord-320092-0qnvydux	108	7	may	may	MD
cord-320092-0qnvydux	108	8	arise	arise	VB
cord-320092-0qnvydux	108	9	from	from	IN
cord-320092-0qnvydux	108	10	this	this	DT
cord-320092-0qnvydux	108	11	potential	potential	JJ
cord-320092-0qnvydux	108	12	sequence	sequence	NN
cord-320092-0qnvydux	108	13	similarity	similarity	NN
cord-320092-0qnvydux	108	14	is	be	VBZ
cord-320092-0qnvydux	108	15	whether	whether	IN
cord-320092-0qnvydux	108	16	the	the	DT
cord-320092-0qnvydux	108	17	comparison	comparison	NN
cord-320092-0qnvydux	108	18	is	be	VBZ
cord-320092-0qnvydux	108	19	equal	equal	JJ
cord-320092-0qnvydux	108	20	for	for	IN
cord-320092-0qnvydux	108	21	all	all	DT
cord-320092-0qnvydux	108	22	seven	seven	CD
cord-320092-0qnvydux	108	23	known	know	VBN
cord-320092-0qnvydux	108	24	human	human	JJ
cord-320092-0qnvydux	108	25	coronavirus	coronavirus	NN
cord-320092-0qnvydux	108	26	strains	strain	NNS
cord-320092-0qnvydux	108	27	,	,	,
cord-320092-0qnvydux	108	28	or	or	CC
cord-320092-0qnvydux	108	29	if	if	IN
cord-320092-0qnvydux	108	30	it	-PRON-	PRP
cord-320092-0qnvydux	108	31	is	be	VBZ
cord-320092-0qnvydux	108	32	more	more	RBR
cord-320092-0qnvydux	108	33	limited	limited	JJ
cord-320092-0qnvydux	108	34	to	to	IN
cord-320092-0qnvydux	108	35	the	the	DT
cord-320092-0qnvydux	108	36	severe	severe	JJ
cord-320092-0qnvydux	108	37	disease	disease	NN
cord-320092-0qnvydux	108	38	-	-	HYPH
cord-320092-0qnvydux	108	39	causing	cause	VBG
cord-320092-0qnvydux	108	40	viruses	virus	NNS
cord-320092-0qnvydux	108	41	.	.	.
cord-320092-0qnvydux	109	1	Figure	figure	NN
cord-320092-0qnvydux	109	2	2	2	CD
cord-320092-0qnvydux	109	3	depicts	depict	VBZ
cord-320092-0qnvydux	109	4	a	a	DT
cord-320092-0qnvydux	109	5	sequence	sequence	NN
cord-320092-0qnvydux	109	6	alignment	alignment	NN
cord-320092-0qnvydux	109	7	to	to	TO
cord-320092-0qnvydux	109	8	start	start	VB
cord-320092-0qnvydux	109	9	to	to	TO
cord-320092-0qnvydux	109	10	answer	answer	VB
cord-320092-0qnvydux	109	11	this	this	DT
cord-320092-0qnvydux	109	12	question	question	NN
cord-320092-0qnvydux	109	13	.	.	.
cord-320092-0qnvydux	110	1	The	the	DT
cord-320092-0qnvydux	110	2	alignment	alignment	NN
cord-320092-0qnvydux	110	3	is	be	VBZ
cord-320092-0qnvydux	110	4	restricted	restrict	VBN
cord-320092-0qnvydux	110	5	to	to	IN
cord-320092-0qnvydux	110	6	the	the	DT
cord-320092-0qnvydux	110	7	length	length	NN
cord-320092-0qnvydux	110	8	of	of	IN
cord-320092-0qnvydux	110	9	the	the	DT
cord-320092-0qnvydux	110	10	mature	mature	JJ
cord-320092-0qnvydux	110	11	human	human	JJ
cord-320092-0qnvydux	110	12	hepcidin	hepcidin	NN
cord-320092-0qnvydux	110	13	protein	protein	NN
cord-320092-0qnvydux	110	14	,	,	,
cord-320092-0qnvydux	110	15	which	which	WDT
cord-320092-0qnvydux	110	16	is	be	VBZ
cord-320092-0qnvydux	110	17	depicted	depict	VBN
cord-320092-0qnvydux	110	18	at	at	IN
cord-320092-0qnvydux	110	19	the	the	DT
cord-320092-0qnvydux	110	20	bottom	bottom	NN
cord-320092-0qnvydux	110	21	row	row	NN
cord-320092-0qnvydux	110	22	.	.	.
cord-320092-0qnvydux	111	1	The	the	DT
cord-320092-0qnvydux	111	2	first	first	JJ
cord-320092-0qnvydux	111	3	four	four	CD
cord-320092-0qnvydux	111	4	spike	spike	NN
cord-320092-0qnvydux	111	5	protein	protein	NN
cord-320092-0qnvydux	111	6	sequences	sequence	NNS
cord-320092-0qnvydux	111	7	are	be	VBP
cord-320092-0qnvydux	111	8	comprised	comprise	VBN
cord-320092-0qnvydux	111	9	of	of	IN
cord-320092-0qnvydux	111	10	the	the	DT
cord-320092-0qnvydux	111	11	mild	mild	JJ
cord-320092-0qnvydux	111	12	/	/	SYM
cord-320092-0qnvydux	111	13	asymptomatic	asymptomatic	JJ
cord-320092-0qnvydux	111	14	strains	strain	NNS
cord-320092-0qnvydux	111	15	,	,	,
cord-320092-0qnvydux	111	16	i.e.	i.e.	FW
cord-320092-0qnvydux	111	17	,	,	,
cord-320092-0qnvydux	111	18	229E	229e	CD
cord-320092-0qnvydux	111	19	and	and	CC
cord-320092-0qnvydux	111	20	NL63	NL63	NNP
cord-320092-0qnvydux	111	21	(	(	-LRB-
cord-320092-0qnvydux	111	22	alpha	alpha	NN
cord-320092-0qnvydux	111	23	coronaviruses	coronaviruse	NNS
cord-320092-0qnvydux	111	24	)	)	-RRB-
cord-320092-0qnvydux	111	25	and	and	CC
cord-320092-0qnvydux	111	26	HKU1	HKU1	NNP
cord-320092-0qnvydux	111	27	and	and	CC
cord-320092-0qnvydux	111	28	OC43	OC43	NNP
cord-320092-0qnvydux	111	29	(	(	-LRB-
cord-320092-0qnvydux	111	30	beta	beta	NN
cord-320092-0qnvydux	111	31	coronaviruses	coronaviruse	NNS
cord-320092-0qnvydux	111	32	)	)	-RRB-
cord-320092-0qnvydux	111	33	.	.	.
cord-320092-0qnvydux	112	1	These	these	DT
cord-320092-0qnvydux	112	2	are	be	VBP
cord-320092-0qnvydux	112	3	followed	follow	VBN
cord-320092-0qnvydux	112	4	by	by	IN
cord-320092-0qnvydux	112	5	the	the	DT
cord-320092-0qnvydux	112	6	spike	spike	NN
cord-320092-0qnvydux	112	7	proteins	protein	NNS
cord-320092-0qnvydux	112	8	of	of	IN
cord-320092-0qnvydux	112	9	MERS	MERS	NNP
cord-320092-0qnvydux	112	10	-	-	HYPH
cord-320092-0qnvydux	112	11	CoV	CoV	NNP
cord-320092-0qnvydux	112	12	,	,	,
cord-320092-0qnvydux	112	13	SARS	SARS	NNP
cord-320092-0qnvydux	112	14	-	-	HYPH
cord-320092-0qnvydux	112	15	CoV-1	CoV-1	NNP
cord-320092-0qnvydux	112	16	and	and	CC
cord-320092-0qnvydux	112	17	SARS	SARS	NNP
cord-320092-0qnvydux	112	18	-	-	HYPH
cord-320092-0qnvydux	112	19	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	112	20	.	.	.
cord-320092-0qnvydux	113	1	The	the	DT
cord-320092-0qnvydux	113	2	bat	bat	NN
cord-320092-0qnvydux	113	3	coronavirus	coronavirus	NN
cord-320092-0qnvydux	113	4	sequence	sequence	NN
cord-320092-0qnvydux	113	5	and	and	CC
cord-320092-0qnvydux	113	6	the	the	DT
cord-320092-0qnvydux	113	7	four	four	CD
cord-320092-0qnvydux	113	8	hepcidins	hepcidin	NNS
cord-320092-0qnvydux	113	9	are	be	VBP
cord-320092-0qnvydux	113	10	depicted	depict	VBN
cord-320092-0qnvydux	113	11	in	in	IN
cord-320092-0qnvydux	113	12	the	the	DT
cord-320092-0qnvydux	113	13	same	same	JJ
cord-320092-0qnvydux	113	14	order	order	NN
cord-320092-0qnvydux	113	15	as	as	IN
cord-320092-0qnvydux	113	16	in	in	IN
cord-320092-0qnvydux	113	17	Fig	Fig	NNP
cord-320092-0qnvydux	113	18	.	.	.
cord-320092-0qnvydux	113	19	 	 	_SP
cord-320092-0qnvydux	113	20	1a	1a	NN
cord-320092-0qnvydux	113	21	.	.	.
cord-320092-0qnvydux	114	1	Paying	pay	VBG
cord-320092-0qnvydux	114	2	particular	particular	JJ
cord-320092-0qnvydux	114	3	attention	attention	NN
cord-320092-0qnvydux	114	4	to	to	IN
cord-320092-0qnvydux	114	5	the	the	DT
cord-320092-0qnvydux	114	6	region	region	NN
cord-320092-0qnvydux	114	7	between	between	IN
cord-320092-0qnvydux	114	8	the	the	DT
cord-320092-0qnvydux	114	9	two	two	CD
cord-320092-0qnvydux	114	10	conserved	conserved	JJ
cord-320092-0qnvydux	114	11	cysteines	cysteine	NNS
cord-320092-0qnvydux	114	12	(	(	-LRB-
cord-320092-0qnvydux	114	13	marked	mark	VBN
cord-320092-0qnvydux	114	14	by	by	IN
cord-320092-0qnvydux	114	15	two	two	CD
cord-320092-0qnvydux	114	16	black	black	JJ
cord-320092-0qnvydux	114	17	arrows	arrow	NNS
cord-320092-0qnvydux	114	18	)	)	-RRB-
cord-320092-0qnvydux	114	19	,	,	,
cord-320092-0qnvydux	114	20	there	there	EX
cord-320092-0qnvydux	114	21	appears	appear	VBZ
cord-320092-0qnvydux	114	22	to	to	TO
cord-320092-0qnvydux	114	23	be	be	VB
cord-320092-0qnvydux	114	24	less	less	JJR
cord-320092-0qnvydux	114	25	similarity	similarity	NN
cord-320092-0qnvydux	114	26	in	in	IN
cord-320092-0qnvydux	114	27	the	the	DT
cord-320092-0qnvydux	114	28	motif	motif	NN
cord-320092-0qnvydux	114	29	between	between	IN
cord-320092-0qnvydux	114	30	the	the	DT
cord-320092-0qnvydux	114	31	first	first	JJ
cord-320092-0qnvydux	114	32	four	four	CD
cord-320092-0qnvydux	114	33	spike	spike	NN
cord-320092-0qnvydux	114	34	proteins	protein	NNS
cord-320092-0qnvydux	114	35	than	than	IN
cord-320092-0qnvydux	114	36	the	the	DT
cord-320092-0qnvydux	114	37	rest	rest	NN
cord-320092-0qnvydux	114	38	of	of	IN
cord-320092-0qnvydux	114	39	the	the	DT
cord-320092-0qnvydux	114	40	sequences	sequence	NNS
cord-320092-0qnvydux	114	41	.	.	.
cord-320092-0qnvydux	115	1	Specifically	specifically	RB
cord-320092-0qnvydux	115	2	,	,	,
cord-320092-0qnvydux	115	3	for	for	IN
cord-320092-0qnvydux	115	4	example	example	NN
cord-320092-0qnvydux	115	5	,	,	,
cord-320092-0qnvydux	115	6	a	a	DT
cord-320092-0qnvydux	115	7	'	'	``
cord-320092-0qnvydux	115	8	conserved	conserved	JJ
cord-320092-0qnvydux	115	9	'	'	''
cord-320092-0qnvydux	115	10	glycine	glycine	NN
cord-320092-0qnvydux	115	11	in	in	IN
cord-320092-0qnvydux	115	12	the	the	DT
cord-320092-0qnvydux	115	13	sixth	sixth	JJ
cord-320092-0qnvydux	115	14	position	position	NN
cord-320092-0qnvydux	115	15	from	from	IN
cord-320092-0qnvydux	115	16	the	the	DT
cord-320092-0qnvydux	115	17	first	first	JJ
cord-320092-0qnvydux	115	18	overall	overall	RB
cord-320092-0qnvydux	115	19	-	-	HYPH
cord-320092-0qnvydux	115	20	conserved	conserve	VBN
cord-320092-0qnvydux	115	21	cysteine	cysteine	NN
cord-320092-0qnvydux	115	22	(	(	-LRB-
cord-320092-0qnvydux	115	23	indicated	indicate	VBN
cord-320092-0qnvydux	115	24	with	with	IN
cord-320092-0qnvydux	115	25	a	a	DT
cord-320092-0qnvydux	115	26	red	red	JJ
cord-320092-0qnvydux	115	27	arrow	arrow	NN
cord-320092-0qnvydux	115	28	)	)	-RRB-
cord-320092-0qnvydux	115	29	appears	appear	VBZ
cord-320092-0qnvydux	115	30	to	to	TO
cord-320092-0qnvydux	115	31	be	be	VB
cord-320092-0qnvydux	115	32	an	an	DT
cord-320092-0qnvydux	115	33	important	important	JJ
cord-320092-0qnvydux	115	34	residue	residue	NN
cord-320092-0qnvydux	115	35	that	that	IN
cord-320092-0qnvydux	115	36	groups	group	NNS
cord-320092-0qnvydux	115	37	together	together	RB
cord-320092-0qnvydux	115	38	the	the	DT
cord-320092-0qnvydux	115	39	three	three	CD
cord-320092-0qnvydux	115	40	disease	disease	NN
cord-320092-0qnvydux	115	41	-	-	HYPH
cord-320092-0qnvydux	115	42	causing	cause	VBG
cord-320092-0qnvydux	115	43	spike	spike	NN
cord-320092-0qnvydux	115	44	proteins	protein	NNS
cord-320092-0qnvydux	115	45	with	with	IN
cord-320092-0qnvydux	115	46	the	the	DT
cord-320092-0qnvydux	115	47	bat	bat	NN
cord-320092-0qnvydux	115	48	sequence	sequence	NN
cord-320092-0qnvydux	115	49	and	and	CC
cord-320092-0qnvydux	115	50	the	the	DT
cord-320092-0qnvydux	115	51	two	two	CD
cord-320092-0qnvydux	115	52	teleost	teleost	NN
cord-320092-0qnvydux	115	53	hepcidin	hepcidin	NN
cord-320092-0qnvydux	115	54	proteins	protein	NNS
cord-320092-0qnvydux	115	55	.	.	.
cord-320092-0qnvydux	116	1	How	how	WRB
cord-320092-0qnvydux	116	2	,	,	,
cord-320092-0qnvydux	116	3	if	if	IN
cord-320092-0qnvydux	116	4	at	at	RB
cord-320092-0qnvydux	116	5	all	all	RB
cord-320092-0qnvydux	116	6	,	,	,
cord-320092-0qnvydux	116	7	these	these	DT
cord-320092-0qnvydux	116	8	differences	difference	NNS
cord-320092-0qnvydux	116	9	play	play	VBP
cord-320092-0qnvydux	116	10	out	out	RP
cord-320092-0qnvydux	116	11	in	in	IN
cord-320092-0qnvydux	116	12	the	the	DT
cord-320092-0qnvydux	116	13	cell	cell	NN
cord-320092-0qnvydux	116	14	might	may	MD
cord-320092-0qnvydux	116	15	be	be	VB
cord-320092-0qnvydux	116	16	an	an	DT
cord-320092-0qnvydux	116	17	intriguing	intriguing	JJ
cord-320092-0qnvydux	116	18	experimental	experimental	JJ
cord-320092-0qnvydux	116	19	direction	direction	NN
cord-320092-0qnvydux	116	20	.	.	.
cord-320092-0qnvydux	117	1	What	what	WP
cord-320092-0qnvydux	117	2	can	can	MD
cord-320092-0qnvydux	117	3	also	also	RB
cord-320092-0qnvydux	117	4	be	be	VB
cord-320092-0qnvydux	117	5	noted	note	VBN
cord-320092-0qnvydux	117	6	from	from	IN
cord-320092-0qnvydux	117	7	Fig	Fig	NNP
cord-320092-0qnvydux	117	8	.	.	.
cord-320092-0qnvydux	118	1	2	2	CD
cord-320092-0qnvydux	118	2	is	be	VBZ
cord-320092-0qnvydux	118	3	that	that	IN
cord-320092-0qnvydux	118	4	although	although	IN
cord-320092-0qnvydux	118	5	there	there	EX
cord-320092-0qnvydux	118	6	are	be	VBP
cord-320092-0qnvydux	118	7	appreciable	appreciable	JJ
cord-320092-0qnvydux	118	8	differences	difference	NNS
cord-320092-0qnvydux	118	9	in	in	IN
cord-320092-0qnvydux	118	10	the	the	DT
cord-320092-0qnvydux	118	11	spike	spike	NN
cord-320092-0qnvydux	118	12	protein	protein	NN
cord-320092-0qnvydux	118	13	domains	domain	NNS
cord-320092-0qnvydux	118	14	visualized	visualize	VBN
cord-320092-0qnvydux	118	15	in	in	IN
cord-320092-0qnvydux	118	16	the	the	DT
cord-320092-0qnvydux	118	17	figure	figure	NN
cord-320092-0qnvydux	118	18	between	between	IN
cord-320092-0qnvydux	118	19	the	the	DT
cord-320092-0qnvydux	118	20	MERS	MERS	NNP
cord-320092-0qnvydux	118	21	-	-	HYPH
cord-320092-0qnvydux	118	22	CoV	CoV	NNP
cord-320092-0qnvydux	118	23	and	and	CC
cord-320092-0qnvydux	118	24	the	the	DT
cord-320092-0qnvydux	118	25	two	two	CD
cord-320092-0qnvydux	118	26	SARS	SARS	NNP
cord-320092-0qnvydux	118	27	-	-	HYPH
cord-320092-0qnvydux	118	28	CoV	CoV	NNP
cord-320092-0qnvydux	118	29	sequences	sequence	NNS
cord-320092-0qnvydux	118	30	,	,	,
cord-320092-0qnvydux	118	31	the	the	DT
cord-320092-0qnvydux	118	32	SARS	SARS	NNP
cord-320092-0qnvydux	118	33	-	-	HYPH
cord-320092-0qnvydux	118	34	CoV-1	CoV-1	NNP
cord-320092-0qnvydux	118	35	and	and	CC
cord-320092-0qnvydux	118	36	SARS	SARS	NNP
cord-320092-0qnvydux	118	37	-	-	HYPH
cord-320092-0qnvydux	118	38	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	118	39	spike	spike	NN
cord-320092-0qnvydux	118	40	proteins	protein	NNS
cord-320092-0qnvydux	118	41	are	be	VBP
cord-320092-0qnvydux	118	42	almost	almost	RB
cord-320092-0qnvydux	118	43	identical	identical	JJ
cord-320092-0qnvydux	118	44	in	in	IN
cord-320092-0qnvydux	118	45	this	this	DT
cord-320092-0qnvydux	118	46	region	region	NN
cord-320092-0qnvydux	118	47	(	(	-LRB-
cord-320092-0qnvydux	118	48	the	the	DT
cord-320092-0qnvydux	118	49	tabulated	tabulate	VBN
cord-320092-0qnvydux	118	50	amino	amino	NN
cord-320092-0qnvydux	118	51	acid	acid	NN
cord-320092-0qnvydux	118	52	identity	identity	NN
cord-320092-0qnvydux	118	53	and	and	CC
cord-320092-0qnvydux	118	54	conservation	conservation	NN
cord-320092-0qnvydux	118	55	values	value	NNS
cord-320092-0qnvydux	118	56	shown	show	VBN
cord-320092-0qnvydux	118	57	were	be	VBD
cord-320092-0qnvydux	118	58	calculated	calculate	VBN
cord-320092-0qnvydux	118	59	for	for	IN
cord-320092-0qnvydux	118	60	the	the	DT
cord-320092-0qnvydux	118	61	aligned	align	VBN
cord-320092-0qnvydux	118	62	region	region	NN
cord-320092-0qnvydux	118	63	using	use	VBG
cord-320092-0qnvydux	118	64	the	the	DT
cord-320092-0qnvydux	118	65	AlignX	AlignX	NNP
cord-320092-0qnvydux	118	66	program	program	NN
cord-320092-0qnvydux	118	67	)	)	-RRB-
cord-320092-0qnvydux	118	68	.	.	.
cord-320092-0qnvydux	119	1	Therefore	therefore	RB
cord-320092-0qnvydux	119	2	,	,	,
cord-320092-0qnvydux	119	3	based	base	VBN
cord-320092-0qnvydux	119	4	on	on	IN
cord-320092-0qnvydux	119	5	the	the	DT
cord-320092-0qnvydux	119	6	hypothetical	hypothetical	JJ
cord-320092-0qnvydux	119	7	link	link	NN
cord-320092-0qnvydux	119	8	presented	present	VBN
cord-320092-0qnvydux	119	9	in	in	IN
cord-320092-0qnvydux	119	10	this	this	DT
cord-320092-0qnvydux	119	11	report	report	NN
cord-320092-0qnvydux	119	12	,	,	,
cord-320092-0qnvydux	119	13	it	-PRON-	PRP
cord-320092-0qnvydux	119	14	might	may	MD
cord-320092-0qnvydux	119	15	be	be	VB
cord-320092-0qnvydux	119	16	reasonable	reasonable	JJ
cord-320092-0qnvydux	119	17	to	to	TO
cord-320092-0qnvydux	119	18	assume	assume	VB
cord-320092-0qnvydux	119	19	that	that	IN
cord-320092-0qnvydux	119	20	any	any	DT
cord-320092-0qnvydux	119	21	pathobiological	pathobiological	JJ
cord-320092-0qnvydux	119	22	differences	difference	NNS
cord-320092-0qnvydux	119	23	between	between	IN
cord-320092-0qnvydux	119	24	the	the	DT
cord-320092-0qnvydux	119	25	two	two	CD
cord-320092-0qnvydux	119	26	SARS	SARS	NNP
cord-320092-0qnvydux	119	27	strains	strain	NNS
cord-320092-0qnvydux	119	28	would	would	MD
cord-320092-0qnvydux	119	29	not	not	RB
cord-320092-0qnvydux	119	30	be	be	VB
cord-320092-0qnvydux	119	31	as	as	IN
cord-320092-0qnvydux	119	32	a	a	DT
cord-320092-0qnvydux	119	33	result	result	NN
cord-320092-0qnvydux	119	34	of	of	IN
cord-320092-0qnvydux	119	35	any	any	DT
cord-320092-0qnvydux	119	36	differing	differ	VBG
cord-320092-0qnvydux	119	37	biology	biology	NN
cord-320092-0qnvydux	119	38	attributable	attributable	JJ
cord-320092-0qnvydux	119	39	to	to	IN
cord-320092-0qnvydux	119	40	the	the	DT
cord-320092-0qnvydux	119	41	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	119	42	similarity	similarity	NN
cord-320092-0qnvydux	119	43	domain	domain	NN
cord-320092-0qnvydux	119	44	.	.	.
cord-320092-0qnvydux	120	1	For	for	IN
cord-320092-0qnvydux	120	2	reference	reference	NN
cord-320092-0qnvydux	120	3	,	,	,
cord-320092-0qnvydux	120	4	the	the	DT
cord-320092-0qnvydux	120	5	SARS	SARS	NNP
cord-320092-0qnvydux	120	6	-	-	HYPH
cord-320092-0qnvydux	120	7	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	120	8	genome	genome	NN
cord-320092-0qnvydux	120	9	has	have	VBZ
cord-320092-0qnvydux	120	10	been	be	VBN
cord-320092-0qnvydux	120	11	reported	report	VBN
cord-320092-0qnvydux	120	12	to	to	TO
cord-320092-0qnvydux	120	13	be	be	VB
cord-320092-0qnvydux	120	14	96	96	CD
cord-320092-0qnvydux	120	15	%	%	NN
cord-320092-0qnvydux	120	16	identical	identical	JJ
cord-320092-0qnvydux	120	17	to	to	TO
cord-320092-0qnvydux	120	18	bat	bat	VB
cord-320092-0qnvydux	120	19	CoV	CoV	NNP
cord-320092-0qnvydux	120	20	(	(	-LRB-
cord-320092-0qnvydux	120	21	nucleotide	nucleotide	JJ
cord-320092-0qnvydux	120	22	identity	identity	NN
cord-320092-0qnvydux	120	23	)	)	-RRB-
cord-320092-0qnvydux	120	24	,	,	,
cord-320092-0qnvydux	120	25	80	80	CD
cord-320092-0qnvydux	120	26	%	%	NN
cord-320092-0qnvydux	120	27	to	to	IN
cord-320092-0qnvydux	120	28	SARS	SARS	NNP
cord-320092-0qnvydux	120	29	-	-	HYPH
cord-320092-0qnvydux	120	30	CoV-1	CoV-1	NNP
cord-320092-0qnvydux	120	31	,	,	,
cord-320092-0qnvydux	120	32	55	55	CD
cord-320092-0qnvydux	120	33	%	%	NN
cord-320092-0qnvydux	120	34	to	to	IN
cord-320092-0qnvydux	120	35	MERS	MERS	NNP
cord-320092-0qnvydux	120	36	-	-	HYPH
cord-320092-0qnvydux	120	37	CoV	CoV	NNP
cord-320092-0qnvydux	120	38	and	and	CC
cord-320092-0qnvydux	120	39	50	50	CD
cord-320092-0qnvydux	120	40	%	%	NN
cord-320092-0qnvydux	120	41	to	to	IN
cord-320092-0qnvydux	120	42	common	common	JJ
cord-320092-0qnvydux	120	43	cold	cold	JJ
cord-320092-0qnvydux	120	44	CoV	cov	NN
cord-320092-0qnvydux	120	45	(	(	-LRB-
cord-320092-0qnvydux	120	46	e.g.	e.g.	RB
cord-320092-0qnvydux	120	47	,	,	,
cord-320092-0qnvydux	120	48	the	the	DT
cord-320092-0qnvydux	120	49	229E	229e	CD
cord-320092-0qnvydux	120	50	and	and	CC
cord-320092-0qnvydux	120	51	OC43	OC43	NNP
cord-320092-0qnvydux	120	52	strains	strain	VBZ
cord-320092-0qnvydux	120	53	)	)	-RRB-
cord-320092-0qnvydux	120	54	[	[	-LRB-
cord-320092-0qnvydux	120	55	13	13	CD
cord-320092-0qnvydux	120	56	]	]	-RRB-
cord-320092-0qnvydux	120	57	.	.	.
cord-320092-0qnvydux	121	1	Also	also	RB
cord-320092-0qnvydux	121	2	of	of	IN
cord-320092-0qnvydux	121	3	note	note	NN
cord-320092-0qnvydux	121	4	in	in	IN
cord-320092-0qnvydux	121	5	Fig	Fig	NNP
cord-320092-0qnvydux	121	6	.	.	.
cord-320092-0qnvydux	122	1	2	2	CD
cord-320092-0qnvydux	122	2	is	be	VBZ
cord-320092-0qnvydux	122	3	the	the	DT
cord-320092-0qnvydux	122	4	percentage	percentage	NN
cord-320092-0qnvydux	122	5	residue	residue	NN
cord-320092-0qnvydux	122	6	identity	identity	NN
cord-320092-0qnvydux	122	7	and	and	CC
cord-320092-0qnvydux	122	8	conservation	conservation	NN
cord-320092-0qnvydux	122	9	between	between	IN
cord-320092-0qnvydux	122	10	Takifugu	Takifugu	NNP
cord-320092-0qnvydux	122	11	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	122	12	and	and	CC
cord-320092-0qnvydux	122	13	the	the	DT
cord-320092-0qnvydux	122	14	corresponding	corresponding	JJ
cord-320092-0qnvydux	122	15	bat	bat	NN
cord-320092-0qnvydux	122	16	coronavirus	coronavirus	NN
cord-320092-0qnvydux	122	17	spike	spike	NN
cord-320092-0qnvydux	122	18	protein	protein	NN
cord-320092-0qnvydux	122	19	region	region	NN
cord-320092-0qnvydux	122	20	(	(	-LRB-
cord-320092-0qnvydux	122	21	54	54	CD
cord-320092-0qnvydux	122	22	%	%	NN
cord-320092-0qnvydux	122	23	identity	identity	NN
cord-320092-0qnvydux	122	24	,	,	,
cord-320092-0qnvydux	122	25	62	62	CD
cord-320092-0qnvydux	122	26	%	%	NN
cord-320092-0qnvydux	122	27	conservation	conservation	NN
cord-320092-0qnvydux	122	28	)	)	-RRB-
cord-320092-0qnvydux	122	29	,	,	,
cord-320092-0qnvydux	122	30	which	which	WDT
cord-320092-0qnvydux	122	31	are	be	VBP
cord-320092-0qnvydux	122	32	the	the	DT
cord-320092-0qnvydux	122	33	same	same	JJ
cord-320092-0qnvydux	122	34	identity	identity	NN
cord-320092-0qnvydux	122	35	and	and	CC
cord-320092-0qnvydux	122	36	conservation	conservation	NN
cord-320092-0qnvydux	122	37	values	value	NNS
cord-320092-0qnvydux	122	38	between	between	IN
cord-320092-0qnvydux	122	39	the	the	DT
cord-320092-0qnvydux	122	40	two	two	CD
cord-320092-0qnvydux	122	41	Takifugu	Takifugu	NNP
cord-320092-0qnvydux	122	42	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	122	43	paralogs	paralogs	NNP
cord-320092-0qnvydux	122	44	.	.	.
cord-320092-0qnvydux	123	1	More	more	RBR
cord-320092-0qnvydux	123	2	broadly	broadly	RB
cord-320092-0qnvydux	123	3	,	,	,
cord-320092-0qnvydux	123	4	the	the	DT
cord-320092-0qnvydux	123	5	potential	potential	JJ
cord-320092-0qnvydux	123	6	sequence	sequence	NN
cord-320092-0qnvydux	123	7	link	link	NN
cord-320092-0qnvydux	123	8	reported	report	VBN
cord-320092-0qnvydux	123	9	here	here	RB
cord-320092-0qnvydux	123	10	points	point	VBZ
cord-320092-0qnvydux	123	11	to	to	IN
cord-320092-0qnvydux	123	12	the	the	DT
cord-320092-0qnvydux	123	13	need	need	NN
cord-320092-0qnvydux	123	14	to	to	TO
cord-320092-0qnvydux	123	15	build	build	VB
cord-320092-0qnvydux	123	16	on	on	IN
cord-320092-0qnvydux	123	17	previous	previous	JJ
cord-320092-0qnvydux	123	18	research	research	NN
cord-320092-0qnvydux	123	19	on	on	IN
cord-320092-0qnvydux	123	20	the	the	DT
cord-320092-0qnvydux	123	21	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	123	22	tail	tail	NN
cord-320092-0qnvydux	123	23	of	of	IN
cord-320092-0qnvydux	123	24	the	the	DT
cord-320092-0qnvydux	123	25	spike	spike	NN
cord-320092-0qnvydux	123	26	protein	protein	NN
cord-320092-0qnvydux	123	27	(	(	-LRB-
cord-320092-0qnvydux	123	28	e.g.	e.g.	RB
cord-320092-0qnvydux	123	29	,	,	,
cord-320092-0qnvydux	123	30	refs	ref	NNS
cord-320092-0qnvydux	123	31	.	.	.
cord-320092-0qnvydux	124	1	[	[	-LRB-
cord-320092-0qnvydux	124	2	80	80	CD
cord-320092-0qnvydux	124	3	,	,	,
cord-320092-0qnvydux	124	4	100	100	CD
cord-320092-0qnvydux	124	5	,	,	,
cord-320092-0qnvydux	124	6	101	101	CD
cord-320092-0qnvydux	124	7	]	]	-RRB-
cord-320092-0qnvydux	124	8	)	)	-RRB-
cord-320092-0qnvydux	124	9	to	to	TO
cord-320092-0qnvydux	124	10	better	well	RBR
cord-320092-0qnvydux	124	11	understand	understand	VB
cord-320092-0qnvydux	124	12	its	-PRON-	PRP$
cord-320092-0qnvydux	124	13	distinct	distinct	JJ
cord-320092-0qnvydux	124	14	roles	role	NNS
cord-320092-0qnvydux	124	15	from	from	IN
cord-320092-0qnvydux	124	16	the	the	DT
cord-320092-0qnvydux	124	17	time	time	NN
cord-320092-0qnvydux	124	18	of	of	IN
cord-320092-0qnvydux	124	19	viral	viral	JJ
cord-320092-0qnvydux	124	20	attachment	attachment	NN
cord-320092-0qnvydux	124	21	to	to	IN
cord-320092-0qnvydux	124	22	possible	possible	JJ
cord-320092-0qnvydux	124	23	protein	protein	NN
cord-320092-0qnvydux	124	24	-	-	HYPH
cord-320092-0qnvydux	124	25	protein	protein	NN
cord-320092-0qnvydux	124	26	interactions	interaction	NNS
cord-320092-0qnvydux	124	27	inside	inside	IN
cord-320092-0qnvydux	124	28	the	the	DT
cord-320092-0qnvydux	124	29	host	host	NN
cord-320092-0qnvydux	124	30	cell	cell	NN
cord-320092-0qnvydux	124	31	.	.	.
cord-320092-0qnvydux	125	1	Of	of	IN
cord-320092-0qnvydux	125	2	the	the	DT
cord-320092-0qnvydux	125	3	rare	rare	JJ
cord-320092-0qnvydux	125	4	mutations	mutation	NNS
cord-320092-0qnvydux	125	5	currently	currently	RB
cord-320092-0qnvydux	125	6	reported	report	VBN
cord-320092-0qnvydux	125	7	in	in	IN
cord-320092-0qnvydux	125	8	the	the	DT
cord-320092-0qnvydux	125	9	SARS	SARS	NNP
cord-320092-0qnvydux	125	10	-	-	HYPH
cord-320092-0qnvydux	125	11	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	125	12	spike	spike	NN
cord-320092-0qnvydux	125	13	protein	protein	NN
cord-320092-0qnvydux	125	14	(	(	-LRB-
cord-320092-0qnvydux	125	15	using	use	VBG
cord-320092-0qnvydux	125	16	patient	patient	NN
cord-320092-0qnvydux	125	17	-	-	HYPH
cord-320092-0qnvydux	125	18	isolated	isolate	VBN
cord-320092-0qnvydux	125	19	genomic	genomic	JJ
cord-320092-0qnvydux	125	20	data	datum	NNS
cord-320092-0qnvydux	125	21	in	in	IN
cord-320092-0qnvydux	125	22	the	the	DT
cord-320092-0qnvydux	125	23	GISAID	GISAID	NNP
cord-320092-0qnvydux	125	24	repository	repository	NN
cord-320092-0qnvydux	125	25	)	)	-RRB-
cord-320092-0qnvydux	125	26	,	,	,
cord-320092-0qnvydux	125	27	only	only	RB
cord-320092-0qnvydux	125	28	one	one	CD
cord-320092-0qnvydux	125	29	(	(	-LRB-
cord-320092-0qnvydux	125	30	P1263L	P1263L	NNP
cord-320092-0qnvydux	125	31	)	)	-RRB-
cord-320092-0qnvydux	125	32	appears	appear	VBZ
cord-320092-0qnvydux	125	33	to	to	TO
cord-320092-0qnvydux	125	34	be	be	VB
cord-320092-0qnvydux	125	35	in	in	IN
cord-320092-0qnvydux	125	36	the	the	DT
cord-320092-0qnvydux	125	37	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	125	38	tail	tail	NN
cord-320092-0qnvydux	125	39	domain	domain	NN
cord-320092-0qnvydux	125	40	[	[	-LRB-
cord-320092-0qnvydux	125	41	68	68	CD
cord-320092-0qnvydux	125	42	]	]	-RRB-
cord-320092-0qnvydux	125	43	,	,	,
cord-320092-0qnvydux	125	44	placing	place	VBG
cord-320092-0qnvydux	125	45	it	-PRON-	PRP
cord-320092-0qnvydux	125	46	outside	outside	RB
cord-320092-0qnvydux	125	47	of	of	IN
cord-320092-0qnvydux	125	48	the	the	DT
cord-320092-0qnvydux	125	49	similarity	similarity	NN
cord-320092-0qnvydux	125	50	region	region	NN
cord-320092-0qnvydux	125	51	reported	report	VBN
cord-320092-0qnvydux	125	52	here	here	RB
cord-320092-0qnvydux	125	53	.	.	.
cord-320092-0qnvydux	126	1	Moving	move	VBG
cord-320092-0qnvydux	126	2	back	back	RB
cord-320092-0qnvydux	126	3	to	to	IN
cord-320092-0qnvydux	126	4	the	the	DT
cord-320092-0qnvydux	126	5	biology	biology	NN
cord-320092-0qnvydux	126	6	of	of	IN
cord-320092-0qnvydux	126	7	the	the	DT
cord-320092-0qnvydux	126	8	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	126	9	protein	protein	NN
cord-320092-0qnvydux	126	10	itself	-PRON-	PRP
cord-320092-0qnvydux	126	11	,	,	,
cord-320092-0qnvydux	126	12	as	as	IN
cord-320092-0qnvydux	126	13	noted	note	VBN
cord-320092-0qnvydux	126	14	previously	previously	RB
cord-320092-0qnvydux	126	15	,	,	,
cord-320092-0qnvydux	126	16	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	126	17	binds	bind	VBZ
cord-320092-0qnvydux	126	18	to	to	IN
cord-320092-0qnvydux	126	19	and	and	CC
cord-320092-0qnvydux	126	20	mediates	mediate	VBZ
cord-320092-0qnvydux	126	21	the	the	DT
cord-320092-0qnvydux	126	22	degradation	degradation	NN
cord-320092-0qnvydux	126	23	of	of	IN
cord-320092-0qnvydux	126	24	the	the	DT
cord-320092-0qnvydux	126	25	iron	iron	NN
cord-320092-0qnvydux	126	26	exporter	exporter	NN
cord-320092-0qnvydux	126	27	ferroportin	ferroportin	NNP
cord-320092-0qnvydux	126	28	.	.	.
cord-320092-0qnvydux	127	1	If	if	IN
cord-320092-0qnvydux	127	2	the	the	DT
cord-320092-0qnvydux	127	3	sequence	sequence	NN
cord-320092-0qnvydux	127	4	similarity	similarity	NN
cord-320092-0qnvydux	127	5	reported	report	VBN
cord-320092-0qnvydux	127	6	here	here	RB
cord-320092-0qnvydux	127	7	is	be	VBZ
cord-320092-0qnvydux	127	8	actually	actually	RB
cord-320092-0qnvydux	127	9	playing	play	VBG
cord-320092-0qnvydux	127	10	a	a	DT
cord-320092-0qnvydux	127	11	significant	significant	JJ
cord-320092-0qnvydux	127	12	role	role	NN
cord-320092-0qnvydux	127	13	at	at	IN
cord-320092-0qnvydux	127	14	the	the	DT
cord-320092-0qnvydux	127	15	cellular	cellular	JJ
cord-320092-0qnvydux	127	16	level	level	NN
cord-320092-0qnvydux	127	17	,	,	,
cord-320092-0qnvydux	127	18	could	could	MD
cord-320092-0qnvydux	127	19	it	-PRON-	PRP
cord-320092-0qnvydux	127	20	be	be	VB
cord-320092-0qnvydux	127	21	that	that	IN
cord-320092-0qnvydux	127	22	,	,	,
cord-320092-0qnvydux	127	23	although	although	IN
cord-320092-0qnvydux	127	24	the	the	DT
cord-320092-0qnvydux	127	25	cellular	cellular	JJ
cord-320092-0qnvydux	127	26	localizations	localization	NNS
cord-320092-0qnvydux	127	27	appear	appear	VBP
cord-320092-0qnvydux	127	28	to	to	TO
cord-320092-0qnvydux	127	29	be	be	VB
cord-320092-0qnvydux	127	30	different	different	JJ
cord-320092-0qnvydux	127	31	based	base	VBN
cord-320092-0qnvydux	127	32	on	on	IN
cord-320092-0qnvydux	127	33	current	current	JJ
cord-320092-0qnvydux	127	34	knowledge	knowledge	NN
cord-320092-0qnvydux	127	35	,	,	,
cord-320092-0qnvydux	127	36	the	the	DT
cord-320092-0qnvydux	127	37	SARS	SARS	NNP
cord-320092-0qnvydux	127	38	-	-	HYPH
cord-320092-0qnvydux	127	39	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	127	40	spike	spike	NN
cord-320092-0qnvydux	127	41	protein	protein	NN
cord-320092-0qnvydux	127	42	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	127	43	tail	tail	NN
cord-320092-0qnvydux	127	44	can	can	MD
cord-320092-0qnvydux	127	45	partly	partly	RB
cord-320092-0qnvydux	127	46	mimic	mimic	VB
cord-320092-0qnvydux	127	47	the	the	DT
cord-320092-0qnvydux	127	48	structure	structure	NN
cord-320092-0qnvydux	127	49	of	of	IN
cord-320092-0qnvydux	127	50	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	127	51	and	and	CC
cord-320092-0qnvydux	127	52	interact	interact	VB
cord-320092-0qnvydux	127	53	with	with	IN
cord-320092-0qnvydux	127	54	ferroportin	ferroportin	NNP
cord-320092-0qnvydux	127	55	?	?	.
cord-320092-0qnvydux	128	1	Could	Could	MD
cord-320092-0qnvydux	128	2	the	the	DT
cord-320092-0qnvydux	128	3	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	128	4	tail	tail	NN
cord-320092-0qnvydux	128	5	even	even	RB
cord-320092-0qnvydux	128	6	coordinate	coordinate	VBP
cord-320092-0qnvydux	128	7	and	and	CC
cord-320092-0qnvydux	128	8	bind	bind	VB
cord-320092-0qnvydux	128	9	iron	iron	NN
cord-320092-0qnvydux	128	10	?	?	.
cord-320092-0qnvydux	129	1	These	these	DT
cord-320092-0qnvydux	129	2	remain	remain	VBP
cord-320092-0qnvydux	129	3	to	to	TO
cord-320092-0qnvydux	129	4	be	be	VB
cord-320092-0qnvydux	129	5	investigated	investigate	VBN
cord-320092-0qnvydux	129	6	experimentally	experimentally	RB
cord-320092-0qnvydux	129	7	,	,	,
cord-320092-0qnvydux	129	8	but	but	CC
cord-320092-0qnvydux	129	9	of	of	IN
cord-320092-0qnvydux	129	10	note	note	NN
cord-320092-0qnvydux	129	11	,	,	,
cord-320092-0qnvydux	129	12	Rishi	Rishi	NNP
cord-320092-0qnvydux	129	13	and	and	CC
cord-320092-0qnvydux	129	14	colleagues	colleague	NNS
cord-320092-0qnvydux	129	15	recently	recently	RB
cord-320092-0qnvydux	129	16	reported	report	VBD
cord-320092-0qnvydux	129	17	on	on	IN
cord-320092-0qnvydux	129	18	the	the	DT
cord-320092-0qnvydux	129	19	intracellular	intracellular	JJ
cord-320092-0qnvydux	129	20	localization	localization	NN
cord-320092-0qnvydux	129	21	of	of	IN
cord-320092-0qnvydux	129	22	ferroportin	ferroportin	NN
cord-320092-0qnvydux	129	23	dimers	dimer	NNS
cord-320092-0qnvydux	129	24	,	,	,
cord-320092-0qnvydux	129	25	and	and	CC
cord-320092-0qnvydux	129	26	concluded	conclude	VBD
cord-320092-0qnvydux	129	27	that	that	IN
cord-320092-0qnvydux	129	28	both	both	CC
cord-320092-0qnvydux	129	29	the	the	DT
cord-320092-0qnvydux	129	30	carboxy	carboxy	JJ
cord-320092-0qnvydux	129	31	-	-	HYPH
cord-320092-0qnvydux	129	32	and	and	CC
cord-320092-0qnvydux	129	33	amino	amino	NNS
cord-320092-0qnvydux	129	34	-	-	HYPH
cord-320092-0qnvydux	129	35	termini	terminus	NNS
cord-320092-0qnvydux	129	36	of	of	IN
cord-320092-0qnvydux	129	37	the	the	DT
cord-320092-0qnvydux	129	38	protein	protein	NN
cord-320092-0qnvydux	129	39	are	be	VBP
cord-320092-0qnvydux	129	40	intracellular	intracellular	JJ
cord-320092-0qnvydux	129	41	[	[	-LRB-
cord-320092-0qnvydux	129	42	109	109	CD
cord-320092-0qnvydux	129	43	]	]	-RRB-
cord-320092-0qnvydux	129	44	.	.	.
cord-320092-0qnvydux	130	1	As	as	IN
cord-320092-0qnvydux	130	2	cited	cite	VBN
cord-320092-0qnvydux	130	3	earlier	early	RBR
cord-320092-0qnvydux	130	4	,	,	,
cord-320092-0qnvydux	130	5	the	the	DT
cord-320092-0qnvydux	130	6	details	detail	NNS
cord-320092-0qnvydux	130	7	of	of	IN
cord-320092-0qnvydux	130	8	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	130	9	's	's	POS
cord-320092-0qnvydux	130	10	own	own	JJ
cord-320092-0qnvydux	130	11	interaction	interaction	NN
cord-320092-0qnvydux	130	12	sites	site	NNS
cord-320092-0qnvydux	130	13	with	with	IN
cord-320092-0qnvydux	130	14	ferroportin	ferroportin	NNS
cord-320092-0qnvydux	130	15	remain	remain	VBP
cord-320092-0qnvydux	130	16	the	the	DT
cord-320092-0qnvydux	130	17	subject	subject	NN
cord-320092-0qnvydux	130	18	of	of	IN
cord-320092-0qnvydux	130	19	different	different	JJ
cord-320092-0qnvydux	130	20	structural	structural	JJ
cord-320092-0qnvydux	130	21	determination	determination	NN
cord-320092-0qnvydux	130	22	projects	project	NNS
cord-320092-0qnvydux	130	23	[	[	-LRB-
cord-320092-0qnvydux	130	24	12	12	CD
cord-320092-0qnvydux	130	25	,	,	,
cord-320092-0qnvydux	130	26	18	18	CD
cord-320092-0qnvydux	130	27	,	,	,
cord-320092-0qnvydux	130	28	108	108	CD
cord-320092-0qnvydux	130	29	]	]	-RRB-
cord-320092-0qnvydux	130	30	.	.	.
cord-320092-0qnvydux	131	1	Relatedly	relatedly	RB
cord-320092-0qnvydux	131	2	,	,	,
cord-320092-0qnvydux	131	3	and	and	CC
cord-320092-0qnvydux	131	4	of	of	IN
cord-320092-0qnvydux	131	5	interest	interest	NN
cord-320092-0qnvydux	131	6	,	,	,
cord-320092-0qnvydux	131	7	Neves	Neves	NNP
cord-320092-0qnvydux	131	8	and	and	CC
cord-320092-0qnvydux	131	9	colleagues	colleague	NNS
cord-320092-0qnvydux	131	10	,	,	,
cord-320092-0qnvydux	131	11	using	use	VBG
cord-320092-0qnvydux	131	12	experiments	experiment	NNS
cord-320092-0qnvydux	131	13	on	on	IN
cord-320092-0qnvydux	131	14	iron	iron	NN
cord-320092-0qnvydux	131	15	overload	overload	NN
cord-320092-0qnvydux	131	16	in	in	IN
cord-320092-0qnvydux	131	17	European	european	JJ
cord-320092-0qnvydux	131	18	bass	bass	NN
cord-320092-0qnvydux	131	19	(	(	-LRB-
cord-320092-0qnvydux	131	20	Dicentrarchus	dicentrarchus	JJ
cord-320092-0qnvydux	131	21	labrax	labrax	NNP
cord-320092-0qnvydux	131	22	)	)	-RRB-
cord-320092-0qnvydux	131	23	,	,	,
cord-320092-0qnvydux	131	24	have	have	VBP
cord-320092-0qnvydux	131	25	discussed	discuss	VBN
cord-320092-0qnvydux	131	26	the	the	DT
cord-320092-0qnvydux	131	27	functional	functional	JJ
cord-320092-0qnvydux	131	28	partnership	partnership	NN
cord-320092-0qnvydux	131	29	between	between	IN
cord-320092-0qnvydux	131	30	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	131	31	and	and	CC
cord-320092-0qnvydux	131	32	ferroportin	ferroportin	NN
cord-320092-0qnvydux	131	33	from	from	IN
cord-320092-0qnvydux	131	34	an	an	DT
cord-320092-0qnvydux	131	35	evolutionary	evolutionary	JJ
cord-320092-0qnvydux	131	36	perspective	perspective	NN
cord-320092-0qnvydux	131	37	and	and	CC
cord-320092-0qnvydux	131	38	suggested	suggest	VBD
cord-320092-0qnvydux	131	39	that	that	IN
cord-320092-0qnvydux	131	40	this	this	DT
cord-320092-0qnvydux	131	41	may	may	MD
cord-320092-0qnvydux	131	42	"	"	``
cord-320092-0qnvydux	131	43	open	open	VB
cord-320092-0qnvydux	131	44	new	new	JJ
cord-320092-0qnvydux	131	45	possibilities	possibility	NNS
cord-320092-0qnvydux	131	46	for	for	IN
cord-320092-0qnvydux	131	47	the	the	DT
cord-320092-0qnvydux	131	48	pharmaceutical	pharmaceutical	JJ
cord-320092-0qnvydux	131	49	use	use	NN
cord-320092-0qnvydux	131	50	of	of	IN
cord-320092-0qnvydux	131	51	selected	select	VBN
cord-320092-0qnvydux	131	52	fish	fish	NN
cord-320092-0qnvydux	131	53	[	[	-LRB-
cord-320092-0qnvydux	131	54	…	…	NFP
cord-320092-0qnvydux	131	55	]	]	-RRB-
cord-320092-0qnvydux	131	56	hepcidins	hepcidin	NNS
cord-320092-0qnvydux	131	57	during	during	IN
cord-320092-0qnvydux	131	58	infections	infection	NNS
cord-320092-0qnvydux	131	59	,	,	,
cord-320092-0qnvydux	131	60	with	with	IN
cord-320092-0qnvydux	131	61	no	no	DT
cord-320092-0qnvydux	131	62	impact	impact	NN
cord-320092-0qnvydux	131	63	on	on	IN
cord-320092-0qnvydux	131	64	iron	iron	NN
cord-320092-0qnvydux	131	65	homeostasis	homeostasis	NN
cord-320092-0qnvydux	131	66	"	"	''
cord-320092-0qnvydux	131	67	[	[	-LRB-
cord-320092-0qnvydux	131	68	90	90	CD
cord-320092-0qnvydux	131	69	,	,	,
cord-320092-0qnvydux	131	70	91	91	CD
cord-320092-0qnvydux	131	71	]	]	-RRB-
cord-320092-0qnvydux	131	72	.	.	.
cord-320092-0qnvydux	132	1	Notwithstanding	notwithstanding	IN
cord-320092-0qnvydux	132	2	the	the	DT
cord-320092-0qnvydux	132	3	specificities	specificity	NNS
cord-320092-0qnvydux	132	4	of	of	IN
cord-320092-0qnvydux	132	5	the	the	DT
cord-320092-0qnvydux	132	6	hepcidinferroportin	hepcidinferroportin	NNP
cord-320092-0qnvydux	132	7	interaction	interaction	NN
cord-320092-0qnvydux	132	8	,	,	,
cord-320092-0qnvydux	132	9	the	the	DT
cord-320092-0qnvydux	132	10	sequence	sequence	NN
cord-320092-0qnvydux	132	11	similarity	similarity	NN
cord-320092-0qnvydux	132	12	reported	report	VBN
cord-320092-0qnvydux	132	13	here	here	RB
cord-320092-0qnvydux	132	14	also	also	RB
cord-320092-0qnvydux	132	15	points	point	VBZ
cord-320092-0qnvydux	132	16	to	to	IN
cord-320092-0qnvydux	132	17	a	a	DT
cord-320092-0qnvydux	132	18	possible	possible	JJ
cord-320092-0qnvydux	132	19	broader	broad	JJR
cord-320092-0qnvydux	132	20	focus	focus	NN
cord-320092-0qnvydux	132	21	on	on	IN
cord-320092-0qnvydux	132	22	iron	iron	NN
cord-320092-0qnvydux	132	23	biology	biology	NN
cord-320092-0qnvydux	132	24	.	.	.
cord-320092-0qnvydux	133	1	Following	follow	VBG
cord-320092-0qnvydux	133	2	calcium	calcium	NN
cord-320092-0qnvydux	133	3	,	,	,
cord-320092-0qnvydux	133	4	oxygen	oxygen	NN
cord-320092-0qnvydux	133	5	and	and	CC
cord-320092-0qnvydux	133	6	lead	lead	NN
cord-320092-0qnvydux	133	7	,	,	,
cord-320092-0qnvydux	133	8	iron	iron	NN
cord-320092-0qnvydux	133	9	has	have	VBZ
cord-320092-0qnvydux	133	10	historically	historically	RB
cord-320092-0qnvydux	133	11	been	be	VBN
cord-320092-0qnvydux	133	12	one	one	CD
cord-320092-0qnvydux	133	13	of	of	IN
cord-320092-0qnvydux	133	14	the	the	DT
cord-320092-0qnvydux	133	15	most	most	RBS
cord-320092-0qnvydux	133	16	studied	study	VBN
cord-320092-0qnvydux	133	17	elements	element	NNS
cord-320092-0qnvydux	133	18	in	in	IN
cord-320092-0qnvydux	133	19	cell	cell	NN
cord-320092-0qnvydux	133	20	biology	biology	NN
cord-320092-0qnvydux	133	21	[	[	-LRB-
cord-320092-0qnvydux	133	22	40	40	CD
cord-320092-0qnvydux	133	23	]	]	-RRB-
cord-320092-0qnvydux	133	24	,	,	,
cord-320092-0qnvydux	133	25	and	and	CC
cord-320092-0qnvydux	133	26	as	as	RB
cord-320092-0qnvydux	133	27	such	such	JJ
cord-320092-0qnvydux	133	28	there	there	EX
cord-320092-0qnvydux	133	29	is	be	VBZ
cord-320092-0qnvydux	133	30	a	a	DT
cord-320092-0qnvydux	133	31	vast	vast	JJ
cord-320092-0qnvydux	133	32	body	body	NN
cord-320092-0qnvydux	133	33	of	of	IN
cord-320092-0qnvydux	133	34	(	(	-LRB-
cord-320092-0qnvydux	133	35	at	at	IN
cord-320092-0qnvydux	133	36	times	time	NNS
cord-320092-0qnvydux	133	37	conflicting	conflict	VBG
cord-320092-0qnvydux	133	38	)	)	-RRB-
cord-320092-0qnvydux	133	39	literature	literature	NN
cord-320092-0qnvydux	133	40	to	to	TO
cord-320092-0qnvydux	133	41	draw	draw	VB
cord-320092-0qnvydux	133	42	upon	upon	IN
cord-320092-0qnvydux	133	43	relating	relate	VBG
cord-320092-0qnvydux	133	44	to	to	IN
cord-320092-0qnvydux	133	45	iron	iron	NN
cord-320092-0qnvydux	133	46	in	in	IN
cord-320092-0qnvydux	133	47	coronavirus	coronavirus	NN
cord-320092-0qnvydux	133	48	infections	infection	NNS
cord-320092-0qnvydux	133	49	.	.	.
cord-320092-0qnvydux	134	1	Other	other	JJ
cord-320092-0qnvydux	134	2	investigators	investigator	NNS
cord-320092-0qnvydux	134	3	have	have	VBP
cord-320092-0qnvydux	134	4	reviewed	review	VBN
cord-320092-0qnvydux	134	5	broad	broad	JJ
cord-320092-0qnvydux	134	6	themes	theme	NNS
cord-320092-0qnvydux	134	7	from	from	IN
cord-320092-0qnvydux	134	8	iron	iron	NN
cord-320092-0qnvydux	134	9	biology	biology	NN
cord-320092-0qnvydux	134	10	in	in	IN
cord-320092-0qnvydux	134	11	the	the	DT
cord-320092-0qnvydux	134	12	context	context	NN
cord-320092-0qnvydux	134	13	of	of	IN
cord-320092-0qnvydux	134	14	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	134	15	[	[	-LRB-
cord-320092-0qnvydux	134	16	39	39	CD
cord-320092-0qnvydux	134	17	,	,	,
cord-320092-0qnvydux	134	18	78	78	CD
cord-320092-0qnvydux	134	19	,	,	,
cord-320092-0qnvydux	134	20	79	79	CD
cord-320092-0qnvydux	134	21	]	]	-RRB-
cord-320092-0qnvydux	134	22	,	,	,
cord-320092-0qnvydux	134	23	but	but	CC
cord-320092-0qnvydux	134	24	here	here	RB
cord-320092-0qnvydux	134	25	I	-PRON-	PRP
cord-320092-0qnvydux	134	26	will	will	MD
cord-320092-0qnvydux	134	27	only	only	RB
cord-320092-0qnvydux	134	28	touch	touch	VB
cord-320092-0qnvydux	134	29	upon	upon	IN
cord-320092-0qnvydux	134	30	salient	salient	JJ
cord-320092-0qnvydux	134	31	features	feature	NNS
cord-320092-0qnvydux	134	32	of	of	IN
cord-320092-0qnvydux	134	33	iron	iron	NN
cord-320092-0qnvydux	134	34	biology	biology	NN
cord-320092-0qnvydux	134	35	that	that	WDT
cord-320092-0qnvydux	134	36	revolve	revolve	VBP
cord-320092-0qnvydux	134	37	around	around	IN
cord-320092-0qnvydux	134	38	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	134	39	.	.	.
cord-320092-0qnvydux	135	1	In	in	IN
cord-320092-0qnvydux	135	2	the	the	DT
cord-320092-0qnvydux	135	3	three	three	CD
cord-320092-0qnvydux	135	4	subsections	subsection	NNS
cord-320092-0qnvydux	135	5	that	that	WDT
cord-320092-0qnvydux	135	6	follow	follow	VBP
cord-320092-0qnvydux	135	7	,	,	,
cord-320092-0qnvydux	135	8	I	-PRON-	PRP
cord-320092-0qnvydux	135	9	will	will	MD
cord-320092-0qnvydux	135	10	briefly	briefly	RB
cord-320092-0qnvydux	135	11	discuss	discuss	VB
cord-320092-0qnvydux	135	12	relevant	relevant	JJ
cord-320092-0qnvydux	135	13	and	and	CC
cord-320092-0qnvydux	135	14	recent	recent	JJ
cord-320092-0qnvydux	135	15	research	research	NN
cord-320092-0qnvydux	135	16	with	with	IN
cord-320092-0qnvydux	135	17	Fig	Fig	NNP
cord-320092-0qnvydux	135	18	.	.	.
cord-320092-0qnvydux	136	1	2	2	CD
cord-320092-0qnvydux	136	2	Comparison	comparison	NN
cord-320092-0qnvydux	136	3	of	of	IN
cord-320092-0qnvydux	136	4	the	the	DT
cord-320092-0qnvydux	136	5	core	core	NN
cord-320092-0qnvydux	136	6	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	136	7	-	-	HYPH
cord-320092-0qnvydux	136	8	like	like	JJ
cord-320092-0qnvydux	136	9	motif	motif	NN
cord-320092-0qnvydux	136	10	among	among	IN
cord-320092-0qnvydux	136	11	the	the	DT
cord-320092-0qnvydux	136	12	seven	seven	CD
cord-320092-0qnvydux	136	13	known	know	VBN
cord-320092-0qnvydux	136	14	coronavirus	coronavirus	NN
cord-320092-0qnvydux	136	15	human	human	JJ
cord-320092-0qnvydux	136	16	infection	infection	NN
cord-320092-0qnvydux	136	17	-	-	:
cord-320092-0qnvydux	136	18	causing	cause	VBG
cord-320092-0qnvydux	136	19	strains	strain	NNS
cord-320092-0qnvydux	136	20	.	.	.
cord-320092-0qnvydux	137	1	Following	follow	VBG
cord-320092-0qnvydux	137	2	the	the	DT
cord-320092-0qnvydux	137	3	alignment	alignment	NN
cord-320092-0qnvydux	137	4	presented	present	VBN
cord-320092-0qnvydux	137	5	in	in	IN
cord-320092-0qnvydux	137	6	Fig	Fig	NNP
cord-320092-0qnvydux	137	7	.	.	.
cord-320092-0qnvydux	138	1	1a	1a	LS
cord-320092-0qnvydux	138	2	,	,	,
cord-320092-0qnvydux	138	3	the	the	DT
cord-320092-0qnvydux	138	4	core	core	NN
cord-320092-0qnvydux	138	5	similarity	similarity	NN
cord-320092-0qnvydux	138	6	motif	motif	NN
cord-320092-0qnvydux	138	7	,	,	,
cord-320092-0qnvydux	138	8	corresponding	correspond	VBG
cord-320092-0qnvydux	138	9	to	to	IN
cord-320092-0qnvydux	138	10	the	the	DT
cord-320092-0qnvydux	138	11	length	length	NN
cord-320092-0qnvydux	138	12	of	of	IN
cord-320092-0qnvydux	138	13	the	the	DT
cord-320092-0qnvydux	138	14	mature	mature	JJ
cord-320092-0qnvydux	138	15	human	human	JJ
cord-320092-0qnvydux	138	16	hepcidin	hepcidin	NN
cord-320092-0qnvydux	138	17	sequence	sequence	NN
cord-320092-0qnvydux	138	18	,	,	,
cord-320092-0qnvydux	138	19	is	be	VBZ
cord-320092-0qnvydux	138	20	shown	show	VBN
cord-320092-0qnvydux	138	21	in	in	IN
cord-320092-0qnvydux	138	22	an	an	DT
cord-320092-0qnvydux	138	23	alignment	alignment	NN
cord-320092-0qnvydux	138	24	containing	contain	VBG
cord-320092-0qnvydux	138	25	the	the	DT
cord-320092-0qnvydux	138	26	spike	spike	NN
cord-320092-0qnvydux	138	27	protein	protein	NN
cord-320092-0qnvydux	138	28	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	138	29	domain	domain	NN
cord-320092-0qnvydux	138	30	of	of	IN
cord-320092-0qnvydux	138	31	the	the	DT
cord-320092-0qnvydux	138	32	four	four	CD
cord-320092-0qnvydux	138	33	mild	mild	JJ
cord-320092-0qnvydux	138	34	/	/	SYM
cord-320092-0qnvydux	138	35	asymptomatic	asymptomatic	JJ
cord-320092-0qnvydux	138	36	human	human	JJ
cord-320092-0qnvydux	138	37	coronavirus	coronavirus	NN
cord-320092-0qnvydux	138	38	strains	strain	NNS
cord-320092-0qnvydux	138	39	and	and	CC
cord-320092-0qnvydux	138	40	the	the	DT
cord-320092-0qnvydux	138	41	three	three	CD
cord-320092-0qnvydux	138	42	severedisease	severedisease	NN
cord-320092-0qnvydux	138	43	-	-	HYPH
cord-320092-0qnvydux	138	44	associated	associate	VBN
cord-320092-0qnvydux	138	45	strains	strain	NNS
cord-320092-0qnvydux	138	46	.	.	.
cord-320092-0qnvydux	139	1	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	139	2	sequences	sequence	NNS
cord-320092-0qnvydux	139	3	from	from	IN
cord-320092-0qnvydux	139	4	the	the	DT
cord-320092-0qnvydux	139	5	previous	previous	JJ
cord-320092-0qnvydux	139	6	figure	figure	NN
cord-320092-0qnvydux	139	7	appear	appear	VBP
cord-320092-0qnvydux	139	8	on	on	IN
cord-320092-0qnvydux	139	9	the	the	DT
cord-320092-0qnvydux	139	10	last	last	JJ
cord-320092-0qnvydux	139	11	four	four	CD
cord-320092-0qnvydux	139	12	lines	line	NNS
cord-320092-0qnvydux	139	13	.	.	.
cord-320092-0qnvydux	140	1	The	the	DT
cord-320092-0qnvydux	140	2	alignment	alignment	NN
cord-320092-0qnvydux	140	3	color	color	NN
cord-320092-0qnvydux	140	4	scheme	scheme	NN
cord-320092-0qnvydux	140	5	is	be	VBZ
cord-320092-0qnvydux	140	6	the	the	DT
cord-320092-0qnvydux	140	7	same	same	JJ
cord-320092-0qnvydux	140	8	as	as	IN
cord-320092-0qnvydux	140	9	in	in	IN
cord-320092-0qnvydux	140	10	Fig	Fig	NNP
cord-320092-0qnvydux	140	11	.	.	.
cord-320092-0qnvydux	141	1	1	1	LS
cord-320092-0qnvydux	141	2	.	.	.
cord-320092-0qnvydux	142	1	Focusing	focus	VBG
cord-320092-0qnvydux	142	2	on	on	IN
cord-320092-0qnvydux	142	3	the	the	DT
cord-320092-0qnvydux	142	4	region	region	NN
cord-320092-0qnvydux	142	5	between	between	IN
cord-320092-0qnvydux	142	6	the	the	DT
cord-320092-0qnvydux	142	7	two	two	CD
cord-320092-0qnvydux	142	8	black	black	JJ
cord-320092-0qnvydux	142	9	arrows	arrow	NNS
cord-320092-0qnvydux	142	10	,	,	,
cord-320092-0qnvydux	142	11	fewer	few	JJR
cord-320092-0qnvydux	142	12	similar	similar	JJ
cord-320092-0qnvydux	142	13	residues	residue	NNS
cord-320092-0qnvydux	142	14	could	could	MD
cord-320092-0qnvydux	142	15	be	be	VB
cord-320092-0qnvydux	142	16	observed	observe	VBN
cord-320092-0qnvydux	142	17	between	between	IN
cord-320092-0qnvydux	142	18	the	the	DT
cord-320092-0qnvydux	142	19	group	group	NN
cord-320092-0qnvydux	142	20	of	of	IN
cord-320092-0qnvydux	142	21	mild/	mild/	NNP
cord-320092-0qnvydux	142	22	asymptomatic	asymptomatic	JJ
cord-320092-0qnvydux	142	23	coronavirus	coronavirus	NN
cord-320092-0qnvydux	142	24	strains	strain	NNS
cord-320092-0qnvydux	142	25	and	and	CC
cord-320092-0qnvydux	142	26	the	the	DT
cord-320092-0qnvydux	142	27	MERS	MERS	NNP
cord-320092-0qnvydux	142	28	/	/	SYM
cord-320092-0qnvydux	142	29	SARS	SARS	NNP
cord-320092-0qnvydux	142	30	-	-	HYPH
cord-320092-0qnvydux	142	31	CoV	cov	NN
cord-320092-0qnvydux	142	32	strains	strain	NNS
cord-320092-0qnvydux	142	33	.	.	.
cord-320092-0qnvydux	143	1	One	one	CD
cord-320092-0qnvydux	143	2	such	such	JJ
cord-320092-0qnvydux	143	3	residue	residue	NN
cord-320092-0qnvydux	143	4	that	that	WDT
cord-320092-0qnvydux	143	5	can	can	MD
cord-320092-0qnvydux	143	6	act	act	VB
cord-320092-0qnvydux	143	7	to	to	TO
cord-320092-0qnvydux	143	8	distinguish	distinguish	VB
cord-320092-0qnvydux	143	9	the	the	DT
cord-320092-0qnvydux	143	10	groups	group	NNS
cord-320092-0qnvydux	143	11	is	be	VBZ
cord-320092-0qnvydux	143	12	indicated	indicate	VBN
cord-320092-0qnvydux	143	13	with	with	IN
cord-320092-0qnvydux	143	14	a	a	DT
cord-320092-0qnvydux	143	15	red	red	JJ
cord-320092-0qnvydux	143	16	arrow	arrow	NN
cord-320092-0qnvydux	143	17	.	.	.
cord-320092-0qnvydux	144	1	The	the	DT
cord-320092-0qnvydux	144	2	accession	accession	NN
cord-320092-0qnvydux	144	3	numbers	number	NNS
cord-320092-0qnvydux	144	4	of	of	IN
cord-320092-0qnvydux	144	5	the	the	DT
cord-320092-0qnvydux	144	6	sequences	sequence	NNS
cord-320092-0qnvydux	144	7	shown	show	VBN
cord-320092-0qnvydux	144	8	,	,	,
cord-320092-0qnvydux	144	9	in	in	IN
cord-320092-0qnvydux	144	10	order	order	NN
cord-320092-0qnvydux	144	11	of	of	IN
cord-320092-0qnvydux	144	12	appearance	appearance	NN
cord-320092-0qnvydux	144	13	,	,	,
cord-320092-0qnvydux	144	14	are	be	VBP
cord-320092-0qnvydux	144	15	:	:	:
cord-320092-0qnvydux	144	16	perspectives	perspective	NNS
cord-320092-0qnvydux	144	17	on	on	IN
cord-320092-0qnvydux	144	18	inflammation	inflammation	NN
cord-320092-0qnvydux	144	19	,	,	,
cord-320092-0qnvydux	144	20	hypoxia	hypoxia	NN
cord-320092-0qnvydux	144	21	and	and	CC
cord-320092-0qnvydux	144	22	diagnostics	diagnostic	NNS
cord-320092-0qnvydux	144	23	.	.	.
cord-320092-0qnvydux	145	1	Moreover	moreover	RB
cord-320092-0qnvydux	145	2	,	,	,
cord-320092-0qnvydux	145	3	the	the	DT
cord-320092-0qnvydux	145	4	main	main	JJ
cord-320092-0qnvydux	145	5	themes	theme	NNS
cord-320092-0qnvydux	145	6	discussed	discuss	VBN
cord-320092-0qnvydux	145	7	in	in	IN
cord-320092-0qnvydux	145	8	these	these	DT
cord-320092-0qnvydux	145	9	segments	segment	NNS
cord-320092-0qnvydux	145	10	have	have	VBP
cord-320092-0qnvydux	145	11	been	be	VBN
cord-320092-0qnvydux	145	12	summarized	summarize	VBN
cord-320092-0qnvydux	145	13	pictorially	pictorially	RB
cord-320092-0qnvydux	145	14	in	in	IN
cord-320092-0qnvydux	145	15	Fig	Fig	NNP
cord-320092-0qnvydux	145	16	.	.	.
cord-320092-0qnvydux	146	1	3	3	LS
cord-320092-0qnvydux	146	2	.	.	.
cord-320092-0qnvydux	147	1	Foremost	foremost	RB
cord-320092-0qnvydux	147	2	among	among	IN
cord-320092-0qnvydux	147	3	the	the	DT
cord-320092-0qnvydux	147	4	potential	potential	JJ
cord-320092-0qnvydux	147	5	physiological	physiological	JJ
cord-320092-0qnvydux	147	6	connections	connection	NNS
cord-320092-0qnvydux	147	7	related	relate	VBN
cord-320092-0qnvydux	147	8	to	to	IN
cord-320092-0qnvydux	147	9	the	the	DT
cord-320092-0qnvydux	147	10	present	present	JJ
cord-320092-0qnvydux	147	11	discussion	discussion	NN
cord-320092-0qnvydux	147	12	is	be	VBZ
cord-320092-0qnvydux	147	13	the	the	DT
cord-320092-0qnvydux	147	14	so	so	RB
cord-320092-0qnvydux	147	15	-	-	HYPH
cord-320092-0qnvydux	147	16	called	call	VBN
cord-320092-0qnvydux	147	17	'	'	``
cord-320092-0qnvydux	147	18	cytokine	cytokine	NN
cord-320092-0qnvydux	147	19	storm	storm	NN
cord-320092-0qnvydux	147	20	'	'	''
cord-320092-0qnvydux	147	21	mediated	mediate	VBN
cord-320092-0qnvydux	147	22	by	by	IN
cord-320092-0qnvydux	147	23	interleukin-6	interleukin-6	NNP
cord-320092-0qnvydux	147	24	(	(	-LRB-
cord-320092-0qnvydux	147	25	IL-6	IL-6	NNP
cord-320092-0qnvydux	147	26	)	)	-RRB-
cord-320092-0qnvydux	147	27	reported	report	VBD
cord-320092-0qnvydux	147	28	in	in	IN
cord-320092-0qnvydux	147	29	some	some	DT
cord-320092-0qnvydux	147	30	COVID-19	covid-19	CD
cord-320092-0qnvydux	147	31	patients	patient	NNS
cord-320092-0qnvydux	147	32	[	[	-LRB-
cord-320092-0qnvydux	147	33	70	70	CD
cord-320092-0qnvydux	147	34	,	,	,
cord-320092-0qnvydux	147	35	84	84	CD
cord-320092-0qnvydux	147	36	,	,	,
cord-320092-0qnvydux	147	37	87	87	CD
cord-320092-0qnvydux	147	38	,	,	,
cord-320092-0qnvydux	147	39	138	138	CD
cord-320092-0qnvydux	147	40	]	]	-RRB-
cord-320092-0qnvydux	147	41	.	.	.
cord-320092-0qnvydux	148	1	This	this	DT
cord-320092-0qnvydux	148	2	is	be	VBZ
cord-320092-0qnvydux	148	3	not	not	RB
cord-320092-0qnvydux	148	4	,	,	,
cord-320092-0qnvydux	148	5	however	however	RB
cord-320092-0qnvydux	148	6	,	,	,
cord-320092-0qnvydux	148	7	restricted	restrict	VBN
cord-320092-0qnvydux	148	8	to	to	IN
cord-320092-0qnvydux	148	9	IL-6	IL-6	NNP
cord-320092-0qnvydux	148	10	and	and	CC
cord-320092-0qnvydux	148	11	in	in	IN
cord-320092-0qnvydux	148	12	fact	fact	NN
cord-320092-0qnvydux	148	13	elevated	elevated	JJ
cord-320092-0qnvydux	148	14	levels	level	NNS
cord-320092-0qnvydux	148	15	of	of	IN
cord-320092-0qnvydux	148	16	a	a	DT
cord-320092-0qnvydux	148	17	bundle	bundle	NN
cord-320092-0qnvydux	148	18	of	of	IN
cord-320092-0qnvydux	148	19	pro	pro	JJ
cord-320092-0qnvydux	148	20	-	-	JJ
cord-320092-0qnvydux	148	21	inflammatory	inflammatory	JJ
cord-320092-0qnvydux	148	22	cytokines	cytokine	NNS
cord-320092-0qnvydux	148	23	has	have	VBZ
cord-320092-0qnvydux	148	24	been	be	VBN
cord-320092-0qnvydux	148	25	reported	report	VBN
cord-320092-0qnvydux	148	26	in	in	IN
cord-320092-0qnvydux	148	27	severe	severe	JJ
cord-320092-0qnvydux	148	28	COVID-19	covid-19	JJ
cord-320092-0qnvydux	148	29	cases	case	NNS
cord-320092-0qnvydux	148	30	[	[	-LRB-
cord-320092-0qnvydux	148	31	25	25	CD
cord-320092-0qnvydux	148	32	,	,	,
cord-320092-0qnvydux	148	33	26	26	CD
cord-320092-0qnvydux	148	34	]	]	-RRB-
cord-320092-0qnvydux	148	35	.	.	.
cord-320092-0qnvydux	149	1	Indeed	indeed	RB
cord-320092-0qnvydux	149	2	,	,	,
cord-320092-0qnvydux	149	3	researchers	researcher	NNS
cord-320092-0qnvydux	149	4	have	have	VBP
cord-320092-0qnvydux	149	5	proposed	propose	VBN
cord-320092-0qnvydux	149	6	that	that	IN
cord-320092-0qnvydux	149	7	"	"	``
cord-320092-0qnvydux	149	8	reduced	reduce	VBN
cord-320092-0qnvydux	149	9	innate	innate	JJ
cord-320092-0qnvydux	149	10	antiviral	antiviral	JJ
cord-320092-0qnvydux	149	11	defenses	defense	NNS
cord-320092-0qnvydux	149	12	coupled	couple	VBN
cord-320092-0qnvydux	149	13	with	with	IN
cord-320092-0qnvydux	149	14	exuberant	exuberant	JJ
cord-320092-0qnvydux	149	15	inflammatory	inflammatory	JJ
cord-320092-0qnvydux	149	16	cytokine	cytokine	NN
cord-320092-0qnvydux	149	17	production	production	NN
cord-320092-0qnvydux	149	18	are	be	VBP
cord-320092-0qnvydux	149	19	the	the	DT
cord-320092-0qnvydux	149	20	defining	define	VBG
cord-320092-0qnvydux	149	21	and	and	CC
cord-320092-0qnvydux	149	22	driving	driving	NN
cord-320092-0qnvydux	149	23	features	feature	NNS
cord-320092-0qnvydux	149	24	of	of	IN
cord-320092-0qnvydux	149	25	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	149	26	"	"	''
cord-320092-0qnvydux	149	27	[	[	-LRB-
cord-320092-0qnvydux	149	28	19	19	CD
cord-320092-0qnvydux	149	29	]	]	-RRB-
cord-320092-0qnvydux	149	30	.	.	.
cord-320092-0qnvydux	150	1	In	in	IN
cord-320092-0qnvydux	150	2	terms	term	NNS
cord-320092-0qnvydux	150	3	of	of	IN
cord-320092-0qnvydux	150	4	the	the	DT
cord-320092-0qnvydux	150	5	chronology	chronology	NN
cord-320092-0qnvydux	150	6	of	of	IN
cord-320092-0qnvydux	150	7	events	event	NNS
cord-320092-0qnvydux	150	8	,	,	,
cord-320092-0qnvydux	150	9	we	-PRON-	PRP
cord-320092-0qnvydux	150	10	could	could	MD
cord-320092-0qnvydux	150	11	consider	consider	VB
cord-320092-0qnvydux	150	12	an	an	DT
cord-320092-0qnvydux	150	13	initial	initial	JJ
cord-320092-0qnvydux	150	14	"	"	``
cord-320092-0qnvydux	150	15	immune	immune	JJ
cord-320092-0qnvydux	150	16	defense	defense	NN
cord-320092-0qnvydux	150	17	-	-	HYPH
cord-320092-0qnvydux	150	18	based	base	VBN
cord-320092-0qnvydux	150	19	protective	protective	JJ
cord-320092-0qnvydux	150	20	phase	phase	NN
cord-320092-0qnvydux	150	21	"	"	''
cord-320092-0qnvydux	150	22	and	and	CC
cord-320092-0qnvydux	150	23	a	a	DT
cord-320092-0qnvydux	150	24	subsequent	subsequent	JJ
cord-320092-0qnvydux	150	25	"	"	``
cord-320092-0qnvydux	150	26	inflammation	inflammation	NN
cord-320092-0qnvydux	150	27	-	-	HYPH
cord-320092-0qnvydux	150	28	driven	drive	VBN
cord-320092-0qnvydux	150	29	damaging	damaging	JJ
cord-320092-0qnvydux	150	30	phase	phase	NN
cord-320092-0qnvydux	150	31	"	"	''
cord-320092-0qnvydux	150	32	in	in	IN
cord-320092-0qnvydux	150	33	the	the	DT
cord-320092-0qnvydux	150	34	disease	disease	NN
cord-320092-0qnvydux	150	35	[	[	-LRB-
cord-320092-0qnvydux	150	36	116	116	CD
cord-320092-0qnvydux	150	37	]	]	-RRB-
cord-320092-0qnvydux	150	38	.	.	.
cord-320092-0qnvydux	151	1	How	how	WRB
cord-320092-0qnvydux	151	2	could	could	MD
cord-320092-0qnvydux	151	3	these	these	DT
cord-320092-0qnvydux	151	4	relate	relate	VB
cord-320092-0qnvydux	151	5	to	to	IN
cord-320092-0qnvydux	151	6	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	151	7	biology	biology	NN
cord-320092-0qnvydux	151	8	?	?	.
cord-320092-0qnvydux	152	1	First	first	RB
cord-320092-0qnvydux	152	2	and	and	CC
cord-320092-0qnvydux	152	3	foremost	foremost	RB
cord-320092-0qnvydux	152	4	,	,	,
cord-320092-0qnvydux	152	5	an	an	DT
cord-320092-0qnvydux	152	6	early	early	JJ
cord-320092-0qnvydux	152	7	set	set	NN
cord-320092-0qnvydux	152	8	of	of	IN
cord-320092-0qnvydux	152	9	findings	finding	NNS
cord-320092-0qnvydux	152	10	on	on	IN
cord-320092-0qnvydux	152	11	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	152	12	was	be	VBD
cord-320092-0qnvydux	152	13	that	that	IN
cord-320092-0qnvydux	152	14	it	-PRON-	PRP
cord-320092-0qnvydux	152	15	is	be	VBZ
cord-320092-0qnvydux	152	16	regulated	regulate	VBN
cord-320092-0qnvydux	152	17	by	by	IN
cord-320092-0qnvydux	152	18	anemia	anemia	NN
cord-320092-0qnvydux	152	19	,	,	,
cord-320092-0qnvydux	152	20	hypoxia	hypoxia	NN
cord-320092-0qnvydux	152	21	and	and	CC
cord-320092-0qnvydux	152	22	inflammation	inflammation	NN
cord-320092-0qnvydux	152	23	[	[	-LRB-
cord-320092-0qnvydux	152	24	92	92	CD
cord-320092-0qnvydux	152	25	]	]	-RRB-
cord-320092-0qnvydux	152	26	.	.	.
cord-320092-0qnvydux	153	1	A	a	DT
cord-320092-0qnvydux	153	2	general	general	JJ
cord-320092-0qnvydux	153	3	understanding	understanding	NN
cord-320092-0qnvydux	153	4	of	of	IN
cord-320092-0qnvydux	153	5	this	this	DT
cord-320092-0qnvydux	153	6	regulatory	regulatory	JJ
cord-320092-0qnvydux	153	7	network	network	NN
cord-320092-0qnvydux	153	8	is	be	VBZ
cord-320092-0qnvydux	153	9	that	that	IN
cord-320092-0qnvydux	153	10	inflammation	inflammation	NN
cord-320092-0qnvydux	153	11	brought	bring	VBN
cord-320092-0qnvydux	153	12	about	about	RP
cord-320092-0qnvydux	153	13	by	by	IN
cord-320092-0qnvydux	153	14	infections	infection	NNS
cord-320092-0qnvydux	153	15	increases	increase	VBZ
cord-320092-0qnvydux	153	16	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	153	17	production	production	NN
cord-320092-0qnvydux	153	18	,	,	,
cord-320092-0qnvydux	153	19	which	which	WDT
cord-320092-0qnvydux	153	20	in	in	IN
cord-320092-0qnvydux	153	21	turn	turn	NN
cord-320092-0qnvydux	153	22	can	can	MD
cord-320092-0qnvydux	153	23	lead	lead	VB
cord-320092-0qnvydux	153	24	to	to	IN
cord-320092-0qnvydux	153	25	the	the	DT
cord-320092-0qnvydux	153	26	anemia	anemia	NN
cord-320092-0qnvydux	153	27	of	of	IN
cord-320092-0qnvydux	153	28	inflammation	inflammation	NN
cord-320092-0qnvydux	153	29	[	[	-LRB-
cord-320092-0qnvydux	153	30	50	50	CD
cord-320092-0qnvydux	153	31	,	,	,
cord-320092-0qnvydux	153	32	52	52	CD
cord-320092-0qnvydux	153	33	]	]	-RRB-
cord-320092-0qnvydux	153	34	.	.	.
cord-320092-0qnvydux	154	1	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	154	2	production	production	NN
cord-320092-0qnvydux	154	3	in	in	IN
cord-320092-0qnvydux	154	4	the	the	DT
cord-320092-0qnvydux	154	5	liver	liver	NN
cord-320092-0qnvydux	154	6	is	be	VBZ
cord-320092-0qnvydux	154	7	induced	induce	VBN
cord-320092-0qnvydux	154	8	by	by	IN
cord-320092-0qnvydux	154	9	IL-6	IL-6	NNP
cord-320092-0qnvydux	154	10	[	[	-LRB-
cord-320092-0qnvydux	154	11	51	51	CD
cord-320092-0qnvydux	154	12	,	,	,
cord-320092-0qnvydux	154	13	94	94	CD
cord-320092-0qnvydux	154	14	]	]	-RRB-
cord-320092-0qnvydux	154	15	,	,	,
cord-320092-0qnvydux	154	16	and	and	CC
cord-320092-0qnvydux	154	17	it	-PRON-	PRP
cord-320092-0qnvydux	154	18	has	have	VBZ
cord-320092-0qnvydux	154	19	been	be	VBN
cord-320092-0qnvydux	154	20	reported	report	VBN
cord-320092-0qnvydux	154	21	that	that	IN
cord-320092-0qnvydux	154	22	hepatic	hepatic	JJ
cord-320092-0qnvydux	154	23	heparan	heparan	NN
cord-320092-0qnvydux	154	24	sulfate	sulfate	NN
cord-320092-0qnvydux	154	25	affects	affect	VBZ
cord-320092-0qnvydux	154	26	and	and	CC
cord-320092-0qnvydux	154	27	regulates	regulate	VBZ
cord-320092-0qnvydux	154	28	IL-6-stimulated	il-6-stimulated	JJ
cord-320092-0qnvydux	154	29	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	154	30	expression	expression	NN
cord-320092-0qnvydux	154	31	[	[	-LRB-
cord-320092-0qnvydux	154	32	103	103	CD
cord-320092-0qnvydux	154	33	]	]	-RRB-
cord-320092-0qnvydux	154	34	.	.	.
cord-320092-0qnvydux	155	1	Furthermore	furthermore	RB
cord-320092-0qnvydux	155	2	,	,	,
cord-320092-0qnvydux	155	3	heparin	heparin	NN
cord-320092-0qnvydux	155	4	,	,	,
cord-320092-0qnvydux	155	5	the	the	DT
cord-320092-0qnvydux	155	6	anticoagulant	anticoagulant	JJ
cord-320092-0qnvydux	155	7	glycosaminoglycan	glycosaminoglycan	NN
cord-320092-0qnvydux	155	8	that	that	WDT
cord-320092-0qnvydux	155	9	is	be	VBZ
cord-320092-0qnvydux	155	10	a	a	DT
cord-320092-0qnvydux	155	11	highly	highly	RB
cord-320092-0qnvydux	155	12	sulfated	sulfate	VBN
cord-320092-0qnvydux	155	13	form	form	NN
cord-320092-0qnvydux	155	14	of	of	IN
cord-320092-0qnvydux	155	15	heparan	heparan	NN
cord-320092-0qnvydux	155	16	sulfate	sulfate	NN
cord-320092-0qnvydux	155	17	,	,	,
cord-320092-0qnvydux	155	18	has	have	VBZ
cord-320092-0qnvydux	155	19	been	be	VBN
cord-320092-0qnvydux	155	20	shown	show	VBN
cord-320092-0qnvydux	155	21	to	to	TO
cord-320092-0qnvydux	155	22	be	be	VB
cord-320092-0qnvydux	155	23	a	a	DT
cord-320092-0qnvydux	155	24	potent	potent	JJ
cord-320092-0qnvydux	155	25	inhibitor	inhibitor	NN
cord-320092-0qnvydux	155	26	of	of	IN
cord-320092-0qnvydux	155	27	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	155	28	expression	expression	NN
cord-320092-0qnvydux	155	29	[	[	-LRB-
cord-320092-0qnvydux	155	30	104	104	CD
cord-320092-0qnvydux	155	31	]	]	-RRB-
cord-320092-0qnvydux	155	32	.	.	.
cord-320092-0qnvydux	156	1	Of	of	IN
cord-320092-0qnvydux	156	2	interest	interest	NN
cord-320092-0qnvydux	156	3	,	,	,
cord-320092-0qnvydux	156	4	anticoagulant	anticoagulant	JJ
cord-320092-0qnvydux	156	5	treatment	treatment	NN
cord-320092-0qnvydux	156	6	has	have	VBZ
cord-320092-0qnvydux	156	7	been	be	VBN
cord-320092-0qnvydux	156	8	reported	report	VBN
cord-320092-0qnvydux	156	9	to	to	TO
cord-320092-0qnvydux	156	10	be	be	VB
cord-320092-0qnvydux	156	11	effective	effective	JJ
cord-320092-0qnvydux	156	12	in	in	IN
cord-320092-0qnvydux	156	13	a	a	DT
cord-320092-0qnvydux	156	14	subset	subset	NN
cord-320092-0qnvydux	156	15	of	of	IN
cord-320092-0qnvydux	156	16	severe	severe	JJ
cord-320092-0qnvydux	156	17	COVID-19	covid-19	JJ
cord-320092-0qnvydux	156	18	patients	patient	NNS
cord-320092-0qnvydux	156	19	[	[	-LRB-
cord-320092-0qnvydux	156	20	120	120	CD
cord-320092-0qnvydux	156	21	]	]	-RRB-
cord-320092-0qnvydux	156	22	[	[	-LRB-
cord-320092-0qnvydux	156	23	121	121	CD
cord-320092-0qnvydux	156	24	]	]	-RRB-
cord-320092-0qnvydux	156	25	[	[	-LRB-
cord-320092-0qnvydux	156	26	122	122	CD
cord-320092-0qnvydux	156	27	]	]	-RRB-
cord-320092-0qnvydux	156	28	,	,	,
cord-320092-0qnvydux	156	29	and	and	CC
cord-320092-0qnvydux	156	30	researchers	researcher	NNS
cord-320092-0qnvydux	156	31	have	have	VBP
cord-320092-0qnvydux	156	32	determined	determine	VBN
cord-320092-0qnvydux	156	33	that	that	IN
cord-320092-0qnvydux	156	34	the	the	DT
cord-320092-0qnvydux	156	35	procoagulant	procoagulant	NN
cord-320092-0qnvydux	156	36	transferrin	transferrin	NN
cord-320092-0qnvydux	156	37	[	[	-LRB-
cord-320092-0qnvydux	156	38	120	120	CD
cord-320092-0qnvydux	156	39	]	]	-RRB-
cord-320092-0qnvydux	156	40	[	[	-LRB-
cord-320092-0qnvydux	156	41	121	121	CD
cord-320092-0qnvydux	156	42	]	]	-RRB-
cord-320092-0qnvydux	156	43	[	[	-LRB-
cord-320092-0qnvydux	156	44	122	122	CD
cord-320092-0qnvydux	156	45	]	]	-RRB-
cord-320092-0qnvydux	156	46	is	be	VBZ
cord-320092-0qnvydux	156	47	upregulated	upregulate	VBN
cord-320092-0qnvydux	156	48	in	in	IN
cord-320092-0qnvydux	156	49	SARS	SARS	NNP
cord-320092-0qnvydux	156	50	-	-	HYPH
cord-320092-0qnvydux	156	51	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	156	52	infections	infection	NNS
cord-320092-0qnvydux	156	53	[	[	-LRB-
cord-320092-0qnvydux	156	54	83	83	CD
cord-320092-0qnvydux	156	55	]	]	-RRB-
cord-320092-0qnvydux	156	56	.	.	.
cord-320092-0qnvydux	157	1	Related	relate	VBN
cord-320092-0qnvydux	157	2	to	to	IN
cord-320092-0qnvydux	157	3	such	such	JJ
cord-320092-0qnvydux	157	4	concerns	concern	NNS
cord-320092-0qnvydux	157	5	with	with	IN
cord-320092-0qnvydux	157	6	inflammation	inflammation	NN
cord-320092-0qnvydux	157	7	and	and	CC
cord-320092-0qnvydux	157	8	coagulation	coagulation	NN
cord-320092-0qnvydux	157	9	in	in	IN
cord-320092-0qnvydux	157	10	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	157	11	,	,	,
cord-320092-0qnvydux	157	12	there	there	EX
cord-320092-0qnvydux	157	13	have	have	VBP
cord-320092-0qnvydux	157	14	also	also	RB
cord-320092-0qnvydux	157	15	recently	recently	RB
cord-320092-0qnvydux	157	16	been	be	VBN
cord-320092-0qnvydux	157	17	proposals	proposal	NNS
cord-320092-0qnvydux	157	18	centered	center	VBN
cord-320092-0qnvydux	157	19	on	on	IN
cord-320092-0qnvydux	157	20	ACE2	ACE2	NNP
cord-320092-0qnvydux	157	21	and	and	CC
cord-320092-0qnvydux	157	22	the	the	DT
cord-320092-0qnvydux	157	23	vasopressor	vasopressor	NN
cord-320092-0qnvydux	157	24	system	system	NN
cord-320092-0qnvydux	157	25	protein	protein	NN
cord-320092-0qnvydux	157	26	bradykinin	bradykinin	NN
cord-320092-0qnvydux	157	27	[	[	-LRB-
cord-320092-0qnvydux	157	28	53	53	CD
cord-320092-0qnvydux	157	29	,	,	,
cord-320092-0qnvydux	157	30	110	110	CD
cord-320092-0qnvydux	157	31	]	]	-RRB-
cord-320092-0qnvydux	157	32	.	.	.
cord-320092-0qnvydux	158	1	These	these	DT
cord-320092-0qnvydux	158	2	are	be	VBP
cord-320092-0qnvydux	158	3	various	various	JJ
cord-320092-0qnvydux	158	4	leads	lead	NNS
cord-320092-0qnvydux	158	5	requiring	require	VBG
cord-320092-0qnvydux	158	6	further	further	JJ
cord-320092-0qnvydux	158	7	investigation	investigation	NN
cord-320092-0qnvydux	158	8	.	.	.
cord-320092-0qnvydux	159	1	It	-PRON-	PRP
cord-320092-0qnvydux	159	2	is	be	VBZ
cord-320092-0qnvydux	159	3	pertinent	pertinent	JJ
cord-320092-0qnvydux	159	4	to	to	TO
cord-320092-0qnvydux	159	5	note	note	VB
cord-320092-0qnvydux	159	6	that	that	IN
cord-320092-0qnvydux	159	7	dysregulated	dysregulate	VBN
cord-320092-0qnvydux	159	8	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	159	9	is	be	VBZ
cord-320092-0qnvydux	159	10	a	a	DT
cord-320092-0qnvydux	159	11	defining	define	VBG
cord-320092-0qnvydux	159	12	feature	feature	NN
cord-320092-0qnvydux	159	13	of	of	IN
cord-320092-0qnvydux	159	14	hemochromatosis	hemochromatosis	NN
cord-320092-0qnvydux	159	15	,	,	,
cord-320092-0qnvydux	159	16	a	a	DT
cord-320092-0qnvydux	159	17	condition	condition	NN
cord-320092-0qnvydux	159	18	characterized	characterize	VBN
cord-320092-0qnvydux	159	19	by	by	IN
cord-320092-0qnvydux	159	20	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	159	21	deficiency	deficiency	NN
cord-320092-0qnvydux	159	22	,	,	,
cord-320092-0qnvydux	159	23	increased	increase	VBN
cord-320092-0qnvydux	159	24	plasma	plasma	NN
cord-320092-0qnvydux	159	25	iron	iron	NN
cord-320092-0qnvydux	159	26	levels	level	NNS
cord-320092-0qnvydux	159	27	and	and	CC
cord-320092-0qnvydux	159	28	transferrin	transferrin	NN
cord-320092-0qnvydux	159	29	saturation	saturation	NN
cord-320092-0qnvydux	159	30	[	[	-LRB-
cord-320092-0qnvydux	159	31	21	21	CD
cord-320092-0qnvydux	159	32	]	]	-RRB-
cord-320092-0qnvydux	159	33	.	.	.
cord-320092-0qnvydux	160	1	In	in	IN
cord-320092-0qnvydux	160	2	addition	addition	NN
cord-320092-0qnvydux	160	3	,	,	,
cord-320092-0qnvydux	160	4	a	a	DT
cord-320092-0qnvydux	160	5	notyet	notyet	RB
cord-320092-0qnvydux	160	6	-	-	HYPH
cord-320092-0qnvydux	160	7	fully	fully	RB
cord-320092-0qnvydux	160	8	-	-	HYPH
cord-320092-0qnvydux	160	9	established	establish	VBN
cord-320092-0qnvydux	160	10	link	link	NN
cord-320092-0qnvydux	160	11	of	of	IN
cord-320092-0qnvydux	160	12	relevance	relevance	NN
cord-320092-0qnvydux	160	13	here	here	RB
cord-320092-0qnvydux	160	14	is	be	VBZ
cord-320092-0qnvydux	160	15	the	the	DT
cord-320092-0qnvydux	160	16	observations	observation	NNS
cord-320092-0qnvydux	160	17	of	of	IN
cord-320092-0qnvydux	160	18	a	a	DT
cord-320092-0qnvydux	160	19	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	160	20	-	-	HYPH
cord-320092-0qnvydux	160	21	disease	disease	NN
cord-320092-0qnvydux	160	22	-	-	HYPH
cord-320092-0qnvydux	160	23	like	like	JJ
cord-320092-0qnvydux	160	24	systemic	systemic	JJ
cord-320092-0qnvydux	160	25	vasculitis	vasculitis	JJ
cord-320092-0qnvydux	160	26	syndrome	syndrome	NN
cord-320092-0qnvydux	160	27	in	in	IN
cord-320092-0qnvydux	160	28	children	child	NNS
cord-320092-0qnvydux	160	29	infected	infect	VBN
cord-320092-0qnvydux	160	30	with	with	IN
cord-320092-0qnvydux	160	31	the	the	DT
cord-320092-0qnvydux	160	32	novel	novel	JJ
cord-320092-0qnvydux	160	33	Fig	Fig	NNP
cord-320092-0qnvydux	160	34	.	.	.
cord-320092-0qnvydux	161	1	3	3	CD
cord-320092-0qnvydux	161	2	Summary	summary	NN
cord-320092-0qnvydux	161	3	of	of	IN
cord-320092-0qnvydux	161	4	salient	salient	JJ
cord-320092-0qnvydux	161	5	facets	facet	NNS
cord-320092-0qnvydux	161	6	of	of	IN
cord-320092-0qnvydux	161	7	coronavirus	coronavirus	NN
cord-320092-0qnvydux	161	8	spike	spike	NN
cord-320092-0qnvydux	161	9	protein	protein	NN
cord-320092-0qnvydux	161	10	and	and	CC
cord-320092-0qnvydux	161	11	human	human	JJ
cord-320092-0qnvydux	161	12	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	161	13	biology	biology	NN
cord-320092-0qnvydux	161	14	.	.	.
cord-320092-0qnvydux	162	1	On	on	IN
cord-320092-0qnvydux	162	2	the	the	DT
cord-320092-0qnvydux	162	3	top	top	JJ
cord-320092-0qnvydux	162	4	left	left	NN
cord-320092-0qnvydux	162	5	of	of	IN
cord-320092-0qnvydux	162	6	the	the	DT
cord-320092-0qnvydux	162	7	figure	figure	NN
cord-320092-0qnvydux	162	8	,	,	,
cord-320092-0qnvydux	162	9	three	three	CD
cord-320092-0qnvydux	162	10	trimeric	trimeric	JJ
cord-320092-0qnvydux	162	11	spike	spike	NN
cord-320092-0qnvydux	162	12	proteins	protein	NNS
cord-320092-0qnvydux	162	13	are	be	VBP
cord-320092-0qnvydux	162	14	depicted	depict	VBN
cord-320092-0qnvydux	162	15	on	on	IN
cord-320092-0qnvydux	162	16	a	a	DT
cord-320092-0qnvydux	162	17	segment	segment	NN
cord-320092-0qnvydux	162	18	of	of	IN
cord-320092-0qnvydux	162	19	the	the	DT
cord-320092-0qnvydux	162	20	viral	viral	JJ
cord-320092-0qnvydux	162	21	membrane	membrane	NN
cord-320092-0qnvydux	162	22	,	,	,
cord-320092-0qnvydux	162	23	two	two	CD
cord-320092-0qnvydux	162	24	in	in	IN
cord-320092-0qnvydux	162	25	a	a	DT
cord-320092-0qnvydux	162	26	figurative	figurative	JJ
cord-320092-0qnvydux	162	27	style	style	NN
cord-320092-0qnvydux	162	28	and	and	CC
cord-320092-0qnvydux	162	29	the	the	DT
cord-320092-0qnvydux	162	30	middle	middle	JJ
cord-320092-0qnvydux	162	31	trimer	trimer	NN
cord-320092-0qnvydux	162	32	in	in	IN
cord-320092-0qnvydux	162	33	a	a	DT
cord-320092-0qnvydux	162	34	more	more	RBR
cord-320092-0qnvydux	162	35	detailed	detailed	JJ
cord-320092-0qnvydux	162	36	domain	domain	NN
cord-320092-0qnvydux	162	37	-	-	HYPH
cord-320092-0qnvydux	162	38	specific	specific	JJ
cord-320092-0qnvydux	162	39	format	format	NN
cord-320092-0qnvydux	162	40	.	.	.
cord-320092-0qnvydux	163	1	One	one	CD
cord-320092-0qnvydux	163	2	palmitate	palmitate	NN
cord-320092-0qnvydux	163	3	is	be	VBZ
cord-320092-0qnvydux	163	4	shown	show	VBN
cord-320092-0qnvydux	163	5	attached	attach	VBN
cord-320092-0qnvydux	163	6	to	to	IN
cord-320092-0qnvydux	163	7	the	the	DT
cord-320092-0qnvydux	163	8	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	163	9	tail	tail	NN
cord-320092-0qnvydux	163	10	of	of	IN
cord-320092-0qnvydux	163	11	the	the	DT
cord-320092-0qnvydux	163	12	spike	spike	NN
cord-320092-0qnvydux	163	13	proteins	protein	NNS
cord-320092-0qnvydux	163	14	,	,	,
cord-320092-0qnvydux	163	15	as	as	IN
cord-320092-0qnvydux	163	16	per	per	IN
cord-320092-0qnvydux	163	17	Fig	Fig	NNP
cord-320092-0qnvydux	163	18	.	.	.
cord-320092-0qnvydux	164	1	1c	1c	NNP
cord-320092-0qnvydux	164	2	.	.	.
cord-320092-0qnvydux	165	1	Following	follow	VBG
cord-320092-0qnvydux	165	2	the	the	DT
cord-320092-0qnvydux	165	3	binding	binding	JJ
cord-320092-0qnvydux	165	4	step	step	NN
cord-320092-0qnvydux	165	5	to	to	IN
cord-320092-0qnvydux	165	6	ACE2	ACE2	NNP
cord-320092-0qnvydux	165	7	,	,	,
cord-320092-0qnvydux	165	8	a	a	DT
cord-320092-0qnvydux	165	9	stylized	stylized	JJ
cord-320092-0qnvydux	165	10	viral	viral	JJ
cord-320092-0qnvydux	165	11	fusion	fusion	NN
cord-320092-0qnvydux	165	12	step	step	NN
cord-320092-0qnvydux	165	13	is	be	VBZ
cord-320092-0qnvydux	165	14	depicted	depict	VBN
cord-320092-0qnvydux	165	15	based	base	VBN
cord-320092-0qnvydux	165	16	on	on	IN
cord-320092-0qnvydux	165	17	refs	ref	NNS
cord-320092-0qnvydux	165	18	.	.	.
cord-320092-0qnvydux	166	1	[	[	-LRB-
cord-320092-0qnvydux	166	2	120	120	CD
cord-320092-0qnvydux	166	3	]	]	-RRB-
cord-320092-0qnvydux	166	4	[	[	-LRB-
cord-320092-0qnvydux	166	5	121	121	CD
cord-320092-0qnvydux	166	6	]	]	-RRB-
cord-320092-0qnvydux	166	7	[	[	-LRB-
cord-320092-0qnvydux	166	8	122	122	CD
cord-320092-0qnvydux	166	9	]	]	-RRB-
cord-320092-0qnvydux	166	10	,	,	,
cord-320092-0qnvydux	166	11	where	where	WRB
cord-320092-0qnvydux	166	12	an	an	DT
cord-320092-0qnvydux	166	13	early	early	JJ
cord-320092-0qnvydux	166	14	fusion	fusion	NN
cord-320092-0qnvydux	166	15	scenario	scenario	NN
cord-320092-0qnvydux	166	16	(	(	-LRB-
cord-320092-0qnvydux	166	17	as	as	IN
cord-320092-0qnvydux	166	18	opposed	oppose	VBN
cord-320092-0qnvydux	166	19	to	to	IN
cord-320092-0qnvydux	166	20	endocytosis	endocytosis	NN
cord-320092-0qnvydux	166	21	)	)	-RRB-
cord-320092-0qnvydux	166	22	is	be	VBZ
cord-320092-0qnvydux	166	23	envisioned	envision	VBN
cord-320092-0qnvydux	166	24	.	.	.
cord-320092-0qnvydux	167	1	The	the	DT
cord-320092-0qnvydux	167	2	assembly	assembly	NN
cord-320092-0qnvydux	167	3	of	of	IN
cord-320092-0qnvydux	167	4	new	new	JJ
cord-320092-0qnvydux	167	5	viral	viral	JJ
cord-320092-0qnvydux	167	6	spike	spike	NN
cord-320092-0qnvydux	167	7	proteins	protein	NNS
cord-320092-0qnvydux	167	8	is	be	VBZ
cord-320092-0qnvydux	167	9	shown	show	VBN
cord-320092-0qnvydux	167	10	to	to	TO
cord-320092-0qnvydux	167	11	be	be	VB
cord-320092-0qnvydux	167	12	taking	take	VBG
cord-320092-0qnvydux	167	13	place	place	NN
cord-320092-0qnvydux	167	14	in	in	IN
cord-320092-0qnvydux	167	15	an	an	DT
cord-320092-0qnvydux	167	16	ER	ER	NNP
cord-320092-0qnvydux	167	17	-	-	HYPH
cord-320092-0qnvydux	167	18	Golgi	Golgi	NNP
cord-320092-0qnvydux	167	19	intermediate	intermediate	JJ
cord-320092-0qnvydux	167	20	compartment	compartment	NN
cord-320092-0qnvydux	167	21	.	.	.
cord-320092-0qnvydux	168	1	On	on	IN
cord-320092-0qnvydux	168	2	the	the	DT
cord-320092-0qnvydux	168	3	right	right	JJ
cord-320092-0qnvydux	168	4	half	half	NN
cord-320092-0qnvydux	168	5	of	of	IN
cord-320092-0qnvydux	168	6	the	the	DT
cord-320092-0qnvydux	168	7	figure	figure	NN
cord-320092-0qnvydux	168	8	,	,	,
cord-320092-0qnvydux	168	9	various	various	JJ
cord-320092-0qnvydux	168	10	elements	element	NNS
cord-320092-0qnvydux	168	11	of	of	IN
cord-320092-0qnvydux	168	12	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	168	13	and	and	CC
cord-320092-0qnvydux	168	14	iron	iron	NN
cord-320092-0qnvydux	168	15	biology	biology	NN
cord-320092-0qnvydux	168	16	are	be	VBP
cord-320092-0qnvydux	168	17	depicted	depict	VBN
cord-320092-0qnvydux	168	18	,	,	,
cord-320092-0qnvydux	168	19	which	which	WDT
cord-320092-0qnvydux	168	20	could	could	MD
cord-320092-0qnvydux	168	21	result	result	VB
cord-320092-0qnvydux	168	22	in	in	IN
cord-320092-0qnvydux	168	23	potential	potential	JJ
cord-320092-0qnvydux	168	24	outcomes	outcome	NNS
cord-320092-0qnvydux	168	25	such	such	JJ
cord-320092-0qnvydux	168	26	as	as	IN
cord-320092-0qnvydux	168	27	coagulopathy	coagulopathy	NN
cord-320092-0qnvydux	168	28	,	,	,
cord-320092-0qnvydux	168	29	ferroptosis	ferroptosis	NNP
cord-320092-0qnvydux	168	30	and	and	CC
cord-320092-0qnvydux	168	31	hyperferritinemia	hyperferritinemia	NNP
cord-320092-0qnvydux	168	32	.	.	.
cord-320092-0qnvydux	169	1	In	in	IN
cord-320092-0qnvydux	169	2	terms	term	NNS
cord-320092-0qnvydux	169	3	of	of	IN
cord-320092-0qnvydux	169	4	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	169	5	's	's	POS
cord-320092-0qnvydux	169	6	binding	binding	NN
cord-320092-0qnvydux	169	7	to	to	IN
cord-320092-0qnvydux	169	8	ferroportin	ferroportin	NNP
cord-320092-0qnvydux	169	9	,	,	,
cord-320092-0qnvydux	169	10	two	two	CD
cord-320092-0qnvydux	169	11	possible	possible	JJ
cord-320092-0qnvydux	169	12	scenarios	scenario	NNS
cord-320092-0qnvydux	169	13	are	be	VBP
cord-320092-0qnvydux	169	14	depicted	depict	VBN
cord-320092-0qnvydux	169	15	,	,	,
cord-320092-0qnvydux	169	16	whereby	whereby	WRB
cord-320092-0qnvydux	169	17	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	169	18	could	could	MD
cord-320092-0qnvydux	169	19	bind	bind	VB
cord-320092-0qnvydux	169	20	to	to	IN
cord-320092-0qnvydux	169	21	the	the	DT
cord-320092-0qnvydux	169	22	extracellular	extracellular	JJ
cord-320092-0qnvydux	169	23	face	face	NN
cord-320092-0qnvydux	169	24	of	of	IN
cord-320092-0qnvydux	169	25	ferroportin	ferroportin	NN
cord-320092-0qnvydux	169	26	or	or	CC
cord-320092-0qnvydux	169	27	deeper	deep	JJR
cord-320092-0qnvydux	169	28	inside	inside	IN
cord-320092-0qnvydux	169	29	the	the	DT
cord-320092-0qnvydux	169	30	transmembrane	transmembrane	NN
cord-320092-0qnvydux	169	31	cavity	cavity	NN
cord-320092-0qnvydux	169	32	.	.	.
cord-320092-0qnvydux	170	1	Lastly	lastly	RB
cord-320092-0qnvydux	170	2	,	,	,
cord-320092-0qnvydux	170	3	the	the	DT
cord-320092-0qnvydux	170	4	geometric	geometric	JJ
cord-320092-0qnvydux	170	5	shapes	shape	NNS
cord-320092-0qnvydux	170	6	for	for	IN
cord-320092-0qnvydux	170	7	the	the	DT
cord-320092-0qnvydux	170	8	spike	spike	NN
cord-320092-0qnvydux	170	9	and	and	CC
cord-320092-0qnvydux	170	10	ACE2	ACE2	NNP
cord-320092-0qnvydux	170	11	proteins	protein	NNS
cord-320092-0qnvydux	170	12	were	be	VBD
cord-320092-0qnvydux	170	13	adapted	adapt	VBN
cord-320092-0qnvydux	170	14	from	from	IN
cord-320092-0qnvydux	170	15	ref	ref	NN
cord-320092-0qnvydux	170	16	.	.	.
cord-320092-0qnvydux	171	1	[	[	-LRB-
cord-320092-0qnvydux	171	2	119	119	CD
cord-320092-0qnvydux	171	3	]	]	-RRB-
cord-320092-0qnvydux	171	4	,	,	,
cord-320092-0qnvydux	171	5	for	for	IN
cord-320092-0qnvydux	171	6	ferroportin	ferroportin	NN
cord-320092-0qnvydux	171	7	from	from	IN
cord-320092-0qnvydux	171	8	ref	ref	NN
cord-320092-0qnvydux	171	9	.	.	.
cord-320092-0qnvydux	172	1	[	[	-LRB-
cord-320092-0qnvydux	172	2	30	30	CD
cord-320092-0qnvydux	172	3	]	]	-RRB-
cord-320092-0qnvydux	172	4	,	,	,
cord-320092-0qnvydux	172	5	and	and	CC
cord-320092-0qnvydux	172	6	for	for	IN
cord-320092-0qnvydux	172	7	ferritin	ferritin	NN
cord-320092-0qnvydux	172	8	from	from	IN
cord-320092-0qnvydux	172	9	ref	ref	NN
cord-320092-0qnvydux	172	10	.	.	.
cord-320092-0qnvydux	173	1	[	[	-LRB-
cord-320092-0qnvydux	173	2	29	29	CD
cord-320092-0qnvydux	173	3	]	]	-RRB-
cord-320092-0qnvydux	173	4	,	,	,
cord-320092-0qnvydux	173	5	all	all	DT
cord-320092-0qnvydux	173	6	with	with	IN
cord-320092-0qnvydux	173	7	permission	permission	NN
cord-320092-0qnvydux	173	8	from	from	IN
cord-320092-0qnvydux	173	9	the	the	DT
cord-320092-0qnvydux	173	10	publisher	publisher	NN
cord-320092-0qnvydux	173	11	(	(	-LRB-
cord-320092-0qnvydux	173	12	Springer	Springer	NNP
cord-320092-0qnvydux	173	13	Nature	Nature	NNP
cord-320092-0qnvydux	173	14	)	)	-RRB-
cord-320092-0qnvydux	174	1	Ehsani	Ehsani	NNP
cord-320092-0qnvydux	174	2	Biology	biology	NN
cord-320092-0qnvydux	174	3	Direct	direct	JJ
cord-320092-0qnvydux	174	4	(	(	-LRB-
cord-320092-0qnvydux	174	5	2020	2020	CD
cord-320092-0qnvydux	174	6	)	)	-RRB-
cord-320092-0qnvydux	174	7	15:19	15:19	CD
cord-320092-0qnvydux	174	8	coronavirus	coronavirus	NN
cord-320092-0qnvydux	174	9	[	[	-LRB-
cord-320092-0qnvydux	174	10	64	64	CD
cord-320092-0qnvydux	174	11	,	,	,
cord-320092-0qnvydux	174	12	127	127	CD
cord-320092-0qnvydux	174	13	]	]	-RRB-
cord-320092-0qnvydux	174	14	,	,	,
cord-320092-0qnvydux	174	15	which	which	WDT
cord-320092-0qnvydux	174	16	is	be	VBZ
cord-320092-0qnvydux	174	17	also	also	RB
cord-320092-0qnvydux	174	18	being	be	VBG
cord-320092-0qnvydux	174	19	called	call	VBN
cord-320092-0qnvydux	174	20	multisystem	multisystem	JJ
cord-320092-0qnvydux	174	21	inflammatory	inflammatory	JJ
cord-320092-0qnvydux	174	22	syndrome	syndrome	NN
cord-320092-0qnvydux	174	23	in	in	IN
cord-320092-0qnvydux	174	24	children	child	NNS
cord-320092-0qnvydux	174	25	(	(	-LRB-
cord-320092-0qnvydux	174	26	MIS	MIS	NNP
cord-320092-0qnvydux	174	27	-	-	HYPH
cord-320092-0qnvydux	174	28	C	C	NNP
cord-320092-0qnvydux	174	29	)	)	-RRB-
cord-320092-0qnvydux	174	30	[	[	-LRB-
cord-320092-0qnvydux	175	1	37	37	CD
cord-320092-0qnvydux	175	2	,	,	,
cord-320092-0qnvydux	175	3	44	44	CD
cord-320092-0qnvydux	175	4	]	]	-RRB-
cord-320092-0qnvydux	175	5	.	.	.
cord-320092-0qnvydux	176	1	Incidentally	incidentally	RB
cord-320092-0qnvydux	176	2	,	,	,
cord-320092-0qnvydux	176	3	an	an	DT
cord-320092-0qnvydux	176	4	association	association	NN
cord-320092-0qnvydux	176	5	between	between	IN
cord-320092-0qnvydux	176	6	a	a	DT
cord-320092-0qnvydux	176	7	novel	novel	JJ
cord-320092-0qnvydux	176	8	human	human	JJ
cord-320092-0qnvydux	176	9	coronavirus	coronavirus	NN
cord-320092-0qnvydux	176	10	and	and	CC
cord-320092-0qnvydux	176	11	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	176	12	disease	disease	NN
cord-320092-0qnvydux	176	13	was	be	VBD
cord-320092-0qnvydux	176	14	reported	report	VBN
cord-320092-0qnvydux	176	15	in	in	IN
cord-320092-0qnvydux	176	16	2005	2005	CD
cord-320092-0qnvydux	176	17	[	[	-LRB-
cord-320092-0qnvydux	176	18	43	43	CD
cord-320092-0qnvydux	176	19	]	]	-RRB-
cord-320092-0qnvydux	176	20	,	,	,
cord-320092-0qnvydux	176	21	although	although	IN
cord-320092-0qnvydux	176	22	other	other	JJ
cord-320092-0qnvydux	176	23	investigators	investigator	NNS
cord-320092-0qnvydux	176	24	were	be	VBD
cord-320092-0qnvydux	176	25	apparently	apparently	RB
cord-320092-0qnvydux	176	26	not	not	RB
cord-320092-0qnvydux	176	27	successful	successful	JJ
cord-320092-0qnvydux	176	28	in	in	IN
cord-320092-0qnvydux	176	29	confirming	confirm	VBG
cord-320092-0qnvydux	176	30	the	the	DT
cord-320092-0qnvydux	176	31	link	link	NN
cord-320092-0qnvydux	176	32	[	[	-LRB-
cord-320092-0qnvydux	176	33	38	38	CD
cord-320092-0qnvydux	176	34	]	]	-RRB-
cord-320092-0qnvydux	176	35	.	.	.
cord-320092-0qnvydux	177	1	Nevertheless	nevertheless	RB
cord-320092-0qnvydux	177	2	,	,	,
cord-320092-0qnvydux	177	3	if	if	IN
cord-320092-0qnvydux	177	4	the	the	DT
cord-320092-0qnvydux	177	5	association	association	NN
cord-320092-0qnvydux	177	6	with	with	IN
cord-320092-0qnvydux	177	7	the	the	DT
cord-320092-0qnvydux	177	8	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	177	9	-	-	HYPH
cord-320092-0qnvydux	177	10	disease	disease	NN
cord-320092-0qnvydux	177	11	-	-	HYPH
cord-320092-0qnvydux	177	12	like	like	JJ
cord-320092-0qnvydux	177	13	syndrome	syndrome	NN
cord-320092-0qnvydux	177	14	is	be	VBZ
cord-320092-0qnvydux	177	15	real	real	JJ
cord-320092-0qnvydux	177	16	,	,	,
cord-320092-0qnvydux	177	17	then	then	RB
cord-320092-0qnvydux	177	18	it	-PRON-	PRP
cord-320092-0qnvydux	177	19	is	be	VBZ
cord-320092-0qnvydux	177	20	noteworthy	noteworthy	JJ
cord-320092-0qnvydux	177	21	that	that	IN
cord-320092-0qnvydux	177	22	increased	increase	VBN
cord-320092-0qnvydux	177	23	hepcidin	hepcidin	NN
cord-320092-0qnvydux	177	24	levels	level	NNS
cord-320092-0qnvydux	177	25	have	have	VBP
cord-320092-0qnvydux	177	26	been	be	VBN
cord-320092-0qnvydux	177	27	suggested	suggest	VBN
cord-320092-0qnvydux	177	28	as	as	IN
cord-320092-0qnvydux	177	29	a	a	DT
cord-320092-0qnvydux	177	30	biomarker	biomarker	NN
cord-320092-0qnvydux	177	31	for	for	IN
cord-320092-0qnvydux	177	32	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	177	33	disease	disease	NN
cord-320092-0qnvydux	177	34	[	[	-LRB-
cord-320092-0qnvydux	177	35	61	61	CD
cord-320092-0qnvydux	177	36	]	]	-RRB-
cord-320092-0qnvydux	177	37	.	.	.
cord-320092-0qnvydux	178	1	As	as	IN
cord-320092-0qnvydux	178	2	opposed	oppose	VBN
cord-320092-0qnvydux	178	3	to	to	IN
cord-320092-0qnvydux	178	4	the	the	DT
cord-320092-0qnvydux	178	5	inflammation	inflammation	NN
cord-320092-0qnvydux	178	6	-	-	HYPH
cord-320092-0qnvydux	178	7	based	base	VBN
cord-320092-0qnvydux	178	8	upregulation	upregulation	NN
cord-320092-0qnvydux	178	9	of	of	IN
cord-320092-0qnvydux	178	10	hepcidin	hepcidin	NN
cord-320092-0qnvydux	178	11	,	,	,
cord-320092-0qnvydux	178	12	anemia	anemia	NN
cord-320092-0qnvydux	178	13	and	and	CC
cord-320092-0qnvydux	178	14	hypoxia	hypoxia	NN
cord-320092-0qnvydux	178	15	are	be	VBP
cord-320092-0qnvydux	178	16	usually	usually	RB
cord-320092-0qnvydux	178	17	taken	take	VBN
cord-320092-0qnvydux	178	18	to	to	TO
cord-320092-0qnvydux	178	19	have	have	VB
cord-320092-0qnvydux	178	20	the	the	DT
cord-320092-0qnvydux	178	21	opposite	opposite	JJ
cord-320092-0qnvydux	178	22	effect	effect	NN
cord-320092-0qnvydux	178	23	on	on	IN
cord-320092-0qnvydux	178	24	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	178	25	's	's	POS
cord-320092-0qnvydux	178	26	expression	expression	NN
cord-320092-0qnvydux	178	27	[	[	-LRB-
cord-320092-0qnvydux	178	28	92	92	CD
cord-320092-0qnvydux	178	29	]	]	-RRB-
cord-320092-0qnvydux	178	30	.	.	.
cord-320092-0qnvydux	179	1	Further	further	RB
cord-320092-0qnvydux	179	2	to	to	IN
cord-320092-0qnvydux	179	3	cytokine	cytokine	JJ
cord-320092-0qnvydux	179	4	storms	storm	NNS
cord-320092-0qnvydux	179	5	and	and	CC
cord-320092-0qnvydux	179	6	characteristic	characteristic	JJ
cord-320092-0qnvydux	179	7	immune	immune	JJ
cord-320092-0qnvydux	179	8	reactions	reaction	NNS
cord-320092-0qnvydux	179	9	,	,	,
cord-320092-0qnvydux	179	10	hypoxemic	hypoxemic	JJ
cord-320092-0qnvydux	179	11	respiratory	respiratory	JJ
cord-320092-0qnvydux	179	12	failure	failure	NN
cord-320092-0qnvydux	179	13	could	could	MD
cord-320092-0qnvydux	179	14	be	be	VB
cord-320092-0qnvydux	179	15	another	another	DT
cord-320092-0qnvydux	179	16	major	major	JJ
cord-320092-0qnvydux	179	17	warning	warning	NN
cord-320092-0qnvydux	179	18	sign	sign	NN
cord-320092-0qnvydux	179	19	in	in	IN
cord-320092-0qnvydux	179	20	COVID-19	covid-19	CD
cord-320092-0qnvydux	179	21	patients	patient	NNS
cord-320092-0qnvydux	179	22	[	[	-LRB-
cord-320092-0qnvydux	179	23	31	31	CD
cord-320092-0qnvydux	179	24	]	]	-RRB-
cord-320092-0qnvydux	179	25	.	.	.
cord-320092-0qnvydux	180	1	Less	less	RBR
cord-320092-0qnvydux	180	2	established	establish	VBN
cord-320092-0qnvydux	180	3	,	,	,
cord-320092-0qnvydux	180	4	but	but	CC
cord-320092-0qnvydux	180	5	still	still	RB
cord-320092-0qnvydux	180	6	important	important	JJ
cord-320092-0qnvydux	180	7	to	to	TO
cord-320092-0qnvydux	180	8	mention	mention	VB
cord-320092-0qnvydux	180	9	,	,	,
cord-320092-0qnvydux	180	10	is	be	VBZ
cord-320092-0qnvydux	180	11	also	also	RB
cord-320092-0qnvydux	180	12	the	the	DT
cord-320092-0qnvydux	180	13	debate	debate	NN
cord-320092-0qnvydux	180	14	surrounding	surround	VBG
cord-320092-0qnvydux	180	15	the	the	DT
cord-320092-0qnvydux	180	16	issue	issue	NN
cord-320092-0qnvydux	180	17	of	of	IN
cord-320092-0qnvydux	180	18	hypoxia	hypoxia	NN
cord-320092-0qnvydux	180	19	/	/	SYM
cord-320092-0qnvydux	180	20	hypoxemia	hypoxemia	NN
cord-320092-0qnvydux	180	21	and	and	CC
cord-320092-0qnvydux	180	22	certain	certain	JJ
cord-320092-0qnvydux	180	23	symptoms	symptom	NNS
cord-320092-0qnvydux	180	24	resembling	resemble	VBG
cord-320092-0qnvydux	180	25	,	,	,
cord-320092-0qnvydux	180	26	but	but	CC
cord-320092-0qnvydux	180	27	differentiable	differentiable	JJ
cord-320092-0qnvydux	180	28	from	from	IN
cord-320092-0qnvydux	180	29	,	,	,
cord-320092-0qnvydux	180	30	altitude	altitude	NN
cord-320092-0qnvydux	180	31	illness	illness	NN
cord-320092-0qnvydux	180	32	[	[	-LRB-
cord-320092-0qnvydux	180	33	8	8	CD
cord-320092-0qnvydux	180	34	,	,	,
cord-320092-0qnvydux	180	35	9	9	CD
cord-320092-0qnvydux	180	36	,	,	,
cord-320092-0qnvydux	180	37	15	15	CD
cord-320092-0qnvydux	180	38	,	,	,
cord-320092-0qnvydux	180	39	54	54	CD
cord-320092-0qnvydux	180	40	]	]	-RRB-
cord-320092-0qnvydux	180	41	.	.	.
cord-320092-0qnvydux	181	1	Congruously	Congruously	NNP
cord-320092-0qnvydux	181	2	,	,	,
cord-320092-0qnvydux	181	3	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	181	4	expression	expression	NN
cord-320092-0qnvydux	181	5	levels	level	NNS
cord-320092-0qnvydux	181	6	have	have	VBP
cord-320092-0qnvydux	181	7	also	also	RB
cord-320092-0qnvydux	181	8	been	be	VBN
cord-320092-0qnvydux	181	9	investigated	investigate	VBN
cord-320092-0qnvydux	181	10	in	in	IN
cord-320092-0qnvydux	181	11	the	the	DT
cord-320092-0qnvydux	181	12	context	context	NN
cord-320092-0qnvydux	181	13	of	of	IN
cord-320092-0qnvydux	181	14	highaltitude	highaltitude	NN
cord-320092-0qnvydux	181	15	acclimatization	acclimatization	NN
cord-320092-0qnvydux	181	16	[	[	-LRB-
cord-320092-0qnvydux	181	17	59	59	CD
cord-320092-0qnvydux	181	18	]	]	-RRB-
cord-320092-0qnvydux	181	19	(	(	-LRB-
cord-320092-0qnvydux	181	20	see	see	VB
cord-320092-0qnvydux	181	21	also	also	RB
cord-320092-0qnvydux	181	22	ref	ref	NN
cord-320092-0qnvydux	181	23	.	.	.
cord-320092-0qnvydux	182	1	[	[	-LRB-
cord-320092-0qnvydux	182	2	27	27	CD
cord-320092-0qnvydux	182	3	]	]	-RRB-
cord-320092-0qnvydux	182	4	)	)	-RRB-
cord-320092-0qnvydux	182	5	.	.	.
cord-320092-0qnvydux	183	1	Moreover	moreover	RB
cord-320092-0qnvydux	183	2	,	,	,
cord-320092-0qnvydux	183	3	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	183	4	levels	level	NNS
cord-320092-0qnvydux	183	5	are	be	VBP
cord-320092-0qnvydux	183	6	known	know	VBN
cord-320092-0qnvydux	183	7	to	to	TO
cord-320092-0qnvydux	183	8	increase	increase	VB
cord-320092-0qnvydux	183	9	in	in	IN
cord-320092-0qnvydux	183	10	patients	patient	NNS
cord-320092-0qnvydux	183	11	with	with	IN
cord-320092-0qnvydux	183	12	acute	acute	JJ
cord-320092-0qnvydux	183	13	respiratory	respiratory	JJ
cord-320092-0qnvydux	183	14	distress	distress	NN
cord-320092-0qnvydux	183	15	syndrome	syndrome	NN
cord-320092-0qnvydux	183	16	(	(	-LRB-
cord-320092-0qnvydux	183	17	ARDS	ARDS	NNP
cord-320092-0qnvydux	183	18	)	)	-RRB-
cord-320092-0qnvydux	183	19	[	[	-LRB-
cord-320092-0qnvydux	183	20	48	48	CD
cord-320092-0qnvydux	183	21	,	,	,
cord-320092-0qnvydux	183	22	86	86	CD
cord-320092-0qnvydux	183	23	]	]	-RRB-
cord-320092-0qnvydux	183	24	.	.	.
cord-320092-0qnvydux	184	1	It	-PRON-	PRP
cord-320092-0qnvydux	184	2	may	may	MD
cord-320092-0qnvydux	184	3	also	also	RB
cord-320092-0qnvydux	184	4	be	be	VB
cord-320092-0qnvydux	184	5	important	important	JJ
cord-320092-0qnvydux	184	6	to	to	TO
cord-320092-0qnvydux	184	7	point	point	VB
cord-320092-0qnvydux	184	8	to	to	IN
cord-320092-0qnvydux	184	9	a	a	DT
cord-320092-0qnvydux	184	10	number	number	NN
cord-320092-0qnvydux	184	11	of	of	IN
cord-320092-0qnvydux	184	12	circumstantial	circumstantial	JJ
cord-320092-0qnvydux	184	13	but	but	CC
cord-320092-0qnvydux	184	14	perhaps	perhaps	RB
cord-320092-0qnvydux	184	15	important	important	JJ
cord-320092-0qnvydux	184	16	findings	finding	NNS
cord-320092-0qnvydux	184	17	in	in	IN
cord-320092-0qnvydux	184	18	the	the	DT
cord-320092-0qnvydux	184	19	literature	literature	NN
cord-320092-0qnvydux	184	20	pertaining	pertain	VBG
cord-320092-0qnvydux	184	21	to	to	IN
cord-320092-0qnvydux	184	22	lung	lung	NN
cord-320092-0qnvydux	184	23	disease	disease	NN
cord-320092-0qnvydux	184	24	.	.	.
cord-320092-0qnvydux	185	1	These	these	DT
cord-320092-0qnvydux	185	2	include	include	VBP
cord-320092-0qnvydux	185	3	(	(	-LRB-
cord-320092-0qnvydux	185	4	i	i	NN
cord-320092-0qnvydux	185	5	)	)	-RRB-
cord-320092-0qnvydux	185	6	a	a	DT
cord-320092-0qnvydux	185	7	link	link	NN
cord-320092-0qnvydux	185	8	between	between	IN
cord-320092-0qnvydux	185	9	SARS	SARS	NNP
cord-320092-0qnvydux	185	10	and	and	CC
cord-320092-0qnvydux	185	11	liver	liver	NN
cord-320092-0qnvydux	185	12	function	function	NN
cord-320092-0qnvydux	185	13	abnormalities	abnormality	NNS
cord-320092-0qnvydux	185	14	[	[	-LRB-
cord-320092-0qnvydux	185	15	74	74	CD
cord-320092-0qnvydux	185	16	]	]	-RRB-
cord-320092-0qnvydux	185	17	,	,	,
cord-320092-0qnvydux	185	18	(	(	-LRB-
cord-320092-0qnvydux	185	19	ii	ii	NN
cord-320092-0qnvydux	185	20	)	)	-RRB-
cord-320092-0qnvydux	186	1	the	the	DT
cord-320092-0qnvydux	186	2	association	association	NNP
cord-320092-0qnvydux	186	3	of	of	IN
cord-320092-0qnvydux	186	4	pulmonary	pulmonary	NNP
cord-320092-0qnvydux	186	5	iron	iron	NN
cord-320092-0qnvydux	186	6	overload	overload	NN
cord-320092-0qnvydux	186	7	and	and	CC
cord-320092-0qnvydux	186	8	restrictive	restrictive	JJ
cord-320092-0qnvydux	186	9	lung	lung	NN
cord-320092-0qnvydux	186	10	disease	disease	NN
cord-320092-0qnvydux	186	11	[	[	-LRB-
cord-320092-0qnvydux	186	12	49	49	CD
cord-320092-0qnvydux	186	13	,	,	,
cord-320092-0qnvydux	186	14	90	90	CD
cord-320092-0qnvydux	186	15	,	,	,
cord-320092-0qnvydux	186	16	91	91	CD
cord-320092-0qnvydux	186	17	]	]	-RRB-
cord-320092-0qnvydux	186	18	,	,	,
cord-320092-0qnvydux	186	19	(	(	-LRB-
cord-320092-0qnvydux	186	20	iii	iii	NN
cord-320092-0qnvydux	186	21	)	)	-RRB-
cord-320092-0qnvydux	187	1	the	the	DT
cord-320092-0qnvydux	187	2	role	role	NN
cord-320092-0qnvydux	187	3	of	of	IN
cord-320092-0qnvydux	187	4	iron	iron	NN
cord-320092-0qnvydux	187	5	in	in	IN
cord-320092-0qnvydux	187	6	pulmonary	pulmonary	JJ
cord-320092-0qnvydux	187	7	fibrosis	fibrosis	NN
cord-320092-0qnvydux	187	8	[	[	-LRB-
cord-320092-0qnvydux	187	9	3	3	CD
cord-320092-0qnvydux	187	10	]	]	-RRB-
cord-320092-0qnvydux	187	11	,	,	,
cord-320092-0qnvydux	187	12	(	(	-LRB-
cord-320092-0qnvydux	187	13	iv	iv	LS
cord-320092-0qnvydux	187	14	)	)	-RRB-
cord-320092-0qnvydux	187	15	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	187	16	's	's	POS
cord-320092-0qnvydux	187	17	modulation	modulation	NN
cord-320092-0qnvydux	187	18	of	of	IN
cord-320092-0qnvydux	187	19	the	the	DT
cord-320092-0qnvydux	187	20	proliferation	proliferation	NN
cord-320092-0qnvydux	187	21	of	of	IN
cord-320092-0qnvydux	187	22	pulmonary	pulmonary	JJ
cord-320092-0qnvydux	187	23	artery	artery	NN
cord-320092-0qnvydux	187	24	smooth	smooth	JJ
cord-320092-0qnvydux	187	25	muscle	muscle	NN
cord-320092-0qnvydux	187	26	cells	cell	NNS
cord-320092-0qnvydux	187	27	[	[	-LRB-
cord-320092-0qnvydux	187	28	107	107	CD
cord-320092-0qnvydux	187	29	]	]	-RRB-
cord-320092-0qnvydux	187	30	,	,	,
cord-320092-0qnvydux	187	31	and	and	CC
cord-320092-0qnvydux	187	32	(	(	-LRB-
cord-320092-0qnvydux	187	33	v	v	LS
cord-320092-0qnvydux	187	34	)	)	-RRB-
cord-320092-0qnvydux	187	35	the	the	DT
cord-320092-0qnvydux	187	36	vital	vital	JJ
cord-320092-0qnvydux	187	37	role	role	NN
cord-320092-0qnvydux	187	38	of	of	IN
cord-320092-0qnvydux	187	39	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	187	40	in	in	IN
cord-320092-0qnvydux	187	41	alveolar	alveolar	JJ
cord-320092-0qnvydux	187	42	macrophage	macrophage	NN
cord-320092-0qnvydux	187	43	function	function	NN
cord-320092-0qnvydux	187	44	[	[	-LRB-
cord-320092-0qnvydux	187	45	98	98	CD
cord-320092-0qnvydux	187	46	]	]	-RRB-
cord-320092-0qnvydux	187	47	.	.	.
cord-320092-0qnvydux	188	1	Furthermore	furthermore	RB
cord-320092-0qnvydux	188	2	,	,	,
cord-320092-0qnvydux	188	3	(	(	-LRB-
cord-320092-0qnvydux	188	4	vi	vi	NNP
cord-320092-0qnvydux	188	5	)	)	-RRB-
cord-320092-0qnvydux	188	6	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	188	7	upregulation	upregulation	NN
cord-320092-0qnvydux	188	8	along	along	IN
cord-320092-0qnvydux	188	9	with	with	IN
cord-320092-0qnvydux	188	10	serum	serum	NN
cord-320092-0qnvydux	188	11	iron	iron	NN
cord-320092-0qnvydux	188	12	reduction	reduction	NN
cord-320092-0qnvydux	188	13	has	have	VBZ
cord-320092-0qnvydux	188	14	been	be	VBN
cord-320092-0qnvydux	188	15	reported	report	VBN
cord-320092-0qnvydux	188	16	in	in	IN
cord-320092-0qnvydux	188	17	influenza	influenza	NN
cord-320092-0qnvydux	188	18	infections	infection	NNS
cord-320092-0qnvydux	188	19	[	[	-LRB-
cord-320092-0qnvydux	188	20	10	10	CD
cord-320092-0qnvydux	188	21	,	,	,
cord-320092-0qnvydux	188	22	45	45	CD
cord-320092-0qnvydux	188	23	]	]	-RRB-
cord-320092-0qnvydux	188	24	.	.	.
cord-320092-0qnvydux	189	1	Importantly	importantly	RB
cord-320092-0qnvydux	189	2	,	,	,
cord-320092-0qnvydux	189	3	however	however	RB
cord-320092-0qnvydux	189	4	,	,	,
cord-320092-0qnvydux	189	5	iron	iron	NN
cord-320092-0qnvydux	189	6	dysregulation	dysregulation	NN
cord-320092-0qnvydux	189	7	changes	change	NNS
cord-320092-0qnvydux	189	8	may	may	MD
cord-320092-0qnvydux	189	9	only	only	RB
cord-320092-0qnvydux	189	10	be	be	VB
cord-320092-0qnvydux	189	11	at	at	IN
cord-320092-0qnvydux	189	12	a	a	DT
cord-320092-0qnvydux	189	13	local	local	JJ
cord-320092-0qnvydux	189	14	cellular	cellular	JJ
cord-320092-0qnvydux	189	15	/	/	SYM
cord-320092-0qnvydux	189	16	tissue	tissue	NN
cord-320092-0qnvydux	189	17	level	level	NN
cord-320092-0qnvydux	189	18	and	and	CC
cord-320092-0qnvydux	189	19	not	not	RB
cord-320092-0qnvydux	189	20	reach	reach	VB
cord-320092-0qnvydux	189	21	a	a	DT
cord-320092-0qnvydux	189	22	systemic	systemic	JJ
cord-320092-0qnvydux	189	23	response	response	NN
cord-320092-0qnvydux	189	24	[	[	-LRB-
cord-320092-0qnvydux	189	25	71	71	CD
cord-320092-0qnvydux	189	26	]	]	-RRB-
cord-320092-0qnvydux	189	27	,	,	,
cord-320092-0qnvydux	189	28	and	and	CC
cord-320092-0qnvydux	189	29	may	may	MD
cord-320092-0qnvydux	189	30	demonstrate	demonstrate	VB
cord-320092-0qnvydux	189	31	selective	selective	JJ
cord-320092-0qnvydux	189	32	tissue	tissue	NN
cord-320092-0qnvydux	189	33	tropisms	tropism	NNS
cord-320092-0qnvydux	189	34	during	during	IN
cord-320092-0qnvydux	189	35	different	different	JJ
cord-320092-0qnvydux	189	36	viral	viral	JJ
cord-320092-0qnvydux	189	37	infections	infection	NNS
cord-320092-0qnvydux	189	38	[	[	-LRB-
cord-320092-0qnvydux	189	39	11	11	CD
cord-320092-0qnvydux	189	40	]	]	-RRB-
cord-320092-0qnvydux	189	41	.	.	.
cord-320092-0qnvydux	190	1	Presently	presently	RB
cord-320092-0qnvydux	190	2	,	,	,
cord-320092-0qnvydux	190	3	dexamethasone	dexamethasone	NN
cord-320092-0qnvydux	190	4	and	and	CC
cord-320092-0qnvydux	190	5	other	other	JJ
cord-320092-0qnvydux	190	6	corticosteroids	corticosteroid	NNS
cord-320092-0qnvydux	190	7	are	be	VBP
cord-320092-0qnvydux	190	8	among	among	IN
cord-320092-0qnvydux	190	9	the	the	DT
cord-320092-0qnvydux	190	10	very	very	RB
cord-320092-0qnvydux	190	11	few	few	JJ
cord-320092-0qnvydux	190	12	widely	widely	RB
cord-320092-0qnvydux	190	13	-	-	HYPH
cord-320092-0qnvydux	190	14	used	use	VBN
cord-320092-0qnvydux	190	15	treatments	treatment	NNS
cord-320092-0qnvydux	190	16	for	for	IN
cord-320092-0qnvydux	190	17	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	190	18	[	[	-LRB-
cord-320092-0qnvydux	190	19	130	130	CD
cord-320092-0qnvydux	190	20	]	]	-RRB-
cord-320092-0qnvydux	190	21	,	,	,
cord-320092-0qnvydux	190	22	and	and	CC
cord-320092-0qnvydux	190	23	it	-PRON-	PRP
cord-320092-0qnvydux	190	24	would	would	MD
cord-320092-0qnvydux	190	25	be	be	VB
cord-320092-0qnvydux	190	26	of	of	IN
cord-320092-0qnvydux	190	27	great	great	JJ
cord-320092-0qnvydux	190	28	significance	significance	NN
cord-320092-0qnvydux	190	29	to	to	TO
cord-320092-0qnvydux	190	30	have	have	VB
cord-320092-0qnvydux	190	31	robust	robust	JJ
cord-320092-0qnvydux	190	32	diagnostic	diagnostic	JJ
cord-320092-0qnvydux	190	33	correlates	correlate	NNS
cord-320092-0qnvydux	190	34	of	of	IN
cord-320092-0qnvydux	190	35	the	the	DT
cord-320092-0qnvydux	190	36	course	course	NN
cord-320092-0qnvydux	190	37	of	of	IN
cord-320092-0qnvydux	190	38	the	the	DT
cord-320092-0qnvydux	190	39	disease	disease	NN
cord-320092-0qnvydux	190	40	.	.	.
cord-320092-0qnvydux	191	1	Could	Could	MD
cord-320092-0qnvydux	191	2	systemic	systemic	JJ
cord-320092-0qnvydux	191	3	changes	change	NNS
cord-320092-0qnvydux	191	4	in	in	IN
cord-320092-0qnvydux	191	5	serum	serum	NN
cord-320092-0qnvydux	191	6	iron	iron	NN
cord-320092-0qnvydux	191	7	levels	level	NNS
cord-320092-0qnvydux	191	8	[	[	-LRB-
cord-320092-0qnvydux	191	9	60	60	CD
cord-320092-0qnvydux	191	10	,	,	,
cord-320092-0qnvydux	191	11	114	114	CD
cord-320092-0qnvydux	191	12	,	,	,
cord-320092-0qnvydux	191	13	126	126	CD
cord-320092-0qnvydux	191	14	,	,	,
cord-320092-0qnvydux	191	15	141	141	CD
cord-320092-0qnvydux	191	16	]	]	-RRB-
cord-320092-0qnvydux	191	17	(	(	-LRB-
cord-320092-0qnvydux	191	18	with	with	IN
cord-320092-0qnvydux	191	19	a	a	DT
cord-320092-0qnvydux	191	20	possible	possible	JJ
cord-320092-0qnvydux	191	21	view	view	NN
cord-320092-0qnvydux	191	22	on	on	IN
cord-320092-0qnvydux	191	23	the	the	DT
cord-320092-0qnvydux	191	24	degree	degree	NN
cord-320092-0qnvydux	191	25	of	of	IN
cord-320092-0qnvydux	191	26	abovenormal	abovenormal	NNP
cord-320092-0qnvydux	191	27	serum	serum	NN
cord-320092-0qnvydux	191	28	ferritin	ferritin	NN
cord-320092-0qnvydux	191	29	in	in	IN
cord-320092-0qnvydux	191	30	patients	patient	NNS
cord-320092-0qnvydux	191	31	[	[	-LRB-
cord-320092-0qnvydux	191	32	25	25	CD
cord-320092-0qnvydux	191	33	,	,	,
cord-320092-0qnvydux	191	34	26	26	CD
cord-320092-0qnvydux	191	35	]	]	-RRB-
cord-320092-0qnvydux	191	36	)	)	-RRB-
cord-320092-0qnvydux	191	37	or	or	CC
cord-320092-0qnvydux	191	38	levels	level	NNS
cord-320092-0qnvydux	191	39	of	of	IN
cord-320092-0qnvydux	191	40	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	191	41	itself	-PRON-	PRP
cord-320092-0qnvydux	191	42	be	be	VB
cord-320092-0qnvydux	191	43	detected	detect	VBN
cord-320092-0qnvydux	191	44	in	in	IN
cord-320092-0qnvydux	191	45	patients	patient	NNS
cord-320092-0qnvydux	191	46	with	with	IN
cord-320092-0qnvydux	191	47	varying	vary	VBG
cord-320092-0qnvydux	191	48	COVID-19	covid-19	JJ
cord-320092-0qnvydux	191	49	severities	severity	NNS
cord-320092-0qnvydux	191	50	?	?	.
cord-320092-0qnvydux	192	1	First	first	RB
cord-320092-0qnvydux	192	2	,	,	,
cord-320092-0qnvydux	192	3	on	on	IN
cord-320092-0qnvydux	192	4	the	the	DT
cord-320092-0qnvydux	192	5	latter	latter	JJ
cord-320092-0qnvydux	192	6	point	point	NN
cord-320092-0qnvydux	192	7	,	,	,
cord-320092-0qnvydux	192	8	researchers	researcher	NNS
cord-320092-0qnvydux	192	9	have	have	VBP
cord-320092-0qnvydux	192	10	recently	recently	RB
cord-320092-0qnvydux	192	11	reported	report	VBN
cord-320092-0qnvydux	192	12	that	that	IN
cord-320092-0qnvydux	192	13	increased	increase	VBN
cord-320092-0qnvydux	192	14	serum	serum	NN
cord-320092-0qnvydux	192	15	levels	level	NNS
cord-320092-0qnvydux	192	16	of	of	IN
cord-320092-0qnvydux	192	17	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	192	18	and	and	CC
cord-320092-0qnvydux	192	19	ferritin	ferritin	NN
cord-320092-0qnvydux	192	20	are	be	VBP
cord-320092-0qnvydux	192	21	indeed	indeed	RB
cord-320092-0qnvydux	192	22	associated	associate	VBN
cord-320092-0qnvydux	192	23	with	with	IN
cord-320092-0qnvydux	192	24	the	the	DT
cord-320092-0qnvydux	192	25	severity	severity	NN
cord-320092-0qnvydux	192	26	of	of	IN
cord-320092-0qnvydux	192	27	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	192	28	[	[	-LRB-
cord-320092-0qnvydux	192	29	143	143	CD
cord-320092-0qnvydux	192	30	,	,	,
cord-320092-0qnvydux	192	31	144	144	CD
cord-320092-0qnvydux	192	32	]	]	-RRB-
cord-320092-0qnvydux	192	33	.	.	.
cord-320092-0qnvydux	193	1	This	this	DT
cord-320092-0qnvydux	193	2	combined	combine	VBN
cord-320092-0qnvydux	193	3	hepcidin	hepcidin	NN
cord-320092-0qnvydux	193	4	/	/	SYM
cord-320092-0qnvydux	193	5	ferritin	ferritin	NN
cord-320092-0qnvydux	193	6	diagnostic	diagnostic	JJ
cord-320092-0qnvydux	193	7	might	may	MD
cord-320092-0qnvydux	193	8	potentially	potentially	RB
cord-320092-0qnvydux	193	9	be	be	VB
cord-320092-0qnvydux	193	10	promising	promising	JJ
cord-320092-0qnvydux	193	11	.	.	.
cord-320092-0qnvydux	194	1	Serum	serum	NN
cord-320092-0qnvydux	194	2	ferritin	ferritin	NN
cord-320092-0qnvydux	194	3	levels	level	NNS
cord-320092-0qnvydux	194	4	alone	alone	RB
cord-320092-0qnvydux	194	5	are	be	VBP
cord-320092-0qnvydux	194	6	usually	usually	RB
cord-320092-0qnvydux	194	7	considered	consider	VBN
cord-320092-0qnvydux	194	8	a	a	DT
cord-320092-0qnvydux	194	9	general	general	JJ
cord-320092-0qnvydux	194	10	indicator	indicator	NN
cord-320092-0qnvydux	194	11	of	of	IN
cord-320092-0qnvydux	194	12	inflammation	inflammation	NN
cord-320092-0qnvydux	194	13	and	and	CC
cord-320092-0qnvydux	194	14	infection	infection	NN
cord-320092-0qnvydux	194	15	,	,	,
cord-320092-0qnvydux	194	16	and	and	CC
cord-320092-0qnvydux	194	17	as	as	IN
cord-320092-0qnvydux	194	18	pointed	point	VBN
cord-320092-0qnvydux	194	19	out	out	RP
cord-320092-0qnvydux	194	20	by	by	IN
cord-320092-0qnvydux	194	21	Baron	Baron	NNP
cord-320092-0qnvydux	194	22	and	and	CC
cord-320092-0qnvydux	194	23	colleagues	colleague	NNS
cord-320092-0qnvydux	194	24	,	,	,
cord-320092-0qnvydux	194	25	"	"	``
cord-320092-0qnvydux	194	26	the	the	DT
cord-320092-0qnvydux	194	27	use	use	NN
cord-320092-0qnvydux	194	28	of	of	IN
cord-320092-0qnvydux	194	29	ferritin	ferritin	NN
cord-320092-0qnvydux	194	30	to	to	TO
cord-320092-0qnvydux	194	31	diagnose	diagnose	VB
cord-320092-0qnvydux	194	32	iron	iron	NN
cord-320092-0qnvydux	194	33	deficiency	deficiency	NN
cord-320092-0qnvydux	194	34	may	may	MD
cord-320092-0qnvydux	194	35	be	be	VB
cord-320092-0qnvydux	194	36	problematic	problematic	JJ
cord-320092-0qnvydux	194	37	in	in	IN
cord-320092-0qnvydux	194	38	patients	patient	NNS
cord-320092-0qnvydux	194	39	with	with	IN
cord-320092-0qnvydux	194	40	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	194	41	disease	disease	NN
cord-320092-0qnvydux	194	42	,	,	,
cord-320092-0qnvydux	194	43	who	who	WP
cord-320092-0qnvydux	194	44	may	may	MD
cord-320092-0qnvydux	194	45	have	have	VB
cord-320092-0qnvydux	194	46	normal	normal	JJ
cord-320092-0qnvydux	194	47	or	or	CC
cord-320092-0qnvydux	194	48	high	high	JJ
cord-320092-0qnvydux	194	49	ferritin	ferritin	NN
cord-320092-0qnvydux	194	50	levels	level	NNS
cord-320092-0qnvydux	194	51	despite	despite	IN
cord-320092-0qnvydux	194	52	very	very	RB
cord-320092-0qnvydux	194	53	low	low	JJ
cord-320092-0qnvydux	194	54	iron	iron	NN
cord-320092-0qnvydux	194	55	stores	store	NNS
cord-320092-0qnvydux	194	56	"	"	''
cord-320092-0qnvydux	194	57	[	[	-LRB-
cord-320092-0qnvydux	194	58	14	14	CD
cord-320092-0qnvydux	194	59	,	,	,
cord-320092-0qnvydux	194	60	143	143	CD
cord-320092-0qnvydux	194	61	,	,	,
cord-320092-0qnvydux	194	62	144	144	CD
cord-320092-0qnvydux	194	63	]	]	-RRB-
cord-320092-0qnvydux	194	64	.	.	.
cord-320092-0qnvydux	195	1	In	in	IN
cord-320092-0qnvydux	195	2	fact	fact	NN
cord-320092-0qnvydux	195	3	,	,	,
cord-320092-0qnvydux	195	4	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	195	5	has	have	VBZ
cord-320092-0qnvydux	195	6	been	be	VBN
cord-320092-0qnvydux	195	7	proposed	propose	VBN
cord-320092-0qnvydux	195	8	to	to	TO
cord-320092-0qnvydux	195	9	be	be	VB
cord-320092-0qnvydux	195	10	a	a	DT
cord-320092-0qnvydux	195	11	part	part	NN
cord-320092-0qnvydux	195	12	of	of	IN
cord-320092-0qnvydux	195	13	the	the	DT
cord-320092-0qnvydux	195	14	hyperferritinemic	hyperferritinemic	JJ
cord-320092-0qnvydux	195	15	spectrum	spectrum	NN
cord-320092-0qnvydux	195	16	of	of	IN
cord-320092-0qnvydux	195	17	conditions	condition	NNS
cord-320092-0qnvydux	195	18	[	[	-LRB-
cord-320092-0qnvydux	195	19	56	56	CD
cord-320092-0qnvydux	195	20	,	,	,
cord-320092-0qnvydux	195	21	99	99	CD
cord-320092-0qnvydux	195	22	]	]	-RRB-
cord-320092-0qnvydux	195	23	.	.	.
cord-320092-0qnvydux	196	1	As	as	IN
cord-320092-0qnvydux	196	2	for	for	IN
cord-320092-0qnvydux	196	3	correlations	correlation	NNS
cord-320092-0qnvydux	196	4	with	with	IN
cord-320092-0qnvydux	196	5	plasma	plasma	NN
cord-320092-0qnvydux	196	6	iron	iron	NN
cord-320092-0qnvydux	196	7	levels	level	NNS
cord-320092-0qnvydux	196	8	,	,	,
cord-320092-0qnvydux	196	9	Shah	Shah	NNP
cord-320092-0qnvydux	196	10	and	and	CC
cord-320092-0qnvydux	196	11	colleagues	colleague	NNS
cord-320092-0qnvydux	196	12	have	have	VBP
cord-320092-0qnvydux	196	13	reported	report	VBN
cord-320092-0qnvydux	196	14	that	that	IN
cord-320092-0qnvydux	196	15	"	"	``
cord-320092-0qnvydux	196	16	compared	compare	VBN
cord-320092-0qnvydux	196	17	with	with	IN
cord-320092-0qnvydux	196	18	patients	patient	NNS
cord-320092-0qnvydux	196	19	with	with	IN
cord-320092-0qnvydux	196	20	non	non	JJ
cord-320092-0qnvydux	196	21	-	-	JJ
cord-320092-0qnvydux	196	22	severe	severe	JJ
cord-320092-0qnvydux	196	23	hypoxemia	hypoxemia	NN
cord-320092-0qnvydux	196	24	,	,	,
cord-320092-0qnvydux	196	25	patients	patient	NNS
cord-320092-0qnvydux	196	26	with	with	IN
cord-320092-0qnvydux	196	27	severe	severe	JJ
cord-320092-0qnvydux	196	28	hypoxemia	hypoxemia	NN
cord-320092-0qnvydux	196	29	had	have	VBD
cord-320092-0qnvydux	196	30	significantly	significantly	RB
cord-320092-0qnvydux	196	31	lower	low	JJR
cord-320092-0qnvydux	196	32	levels	level	NNS
cord-320092-0qnvydux	196	33	of	of	IN
cord-320092-0qnvydux	196	34	serum	serum	NN
cord-320092-0qnvydux	196	35	iron	iron	NN
cord-320092-0qnvydux	196	36	"	"	''
cord-320092-0qnvydux	196	37	,	,	,
cord-320092-0qnvydux	196	38	and	and	CC
cord-320092-0qnvydux	196	39	that	that	IN
cord-320092-0qnvydux	196	40	"	"	``
cord-320092-0qnvydux	196	41	the	the	DT
cord-320092-0qnvydux	196	42	association	association	NNP
cord-320092-0qnvydux	196	43	of	of	IN
cord-320092-0qnvydux	196	44	serum	serum	NNP
cord-320092-0qnvydux	196	45	iron	iron	NN
cord-320092-0qnvydux	196	46	with	with	IN
cord-320092-0qnvydux	196	47	lymphocyte	lymphocyte	NN
cord-320092-0qnvydux	196	48	counts	count	NNS
cord-320092-0qnvydux	196	49	could	could	MD
cord-320092-0qnvydux	196	50	reflect	reflect	VB
cord-320092-0qnvydux	196	51	the	the	DT
cord-320092-0qnvydux	196	52	requirement	requirement	NN
cord-320092-0qnvydux	196	53	of	of	IN
cord-320092-0qnvydux	196	54	the	the	DT
cord-320092-0qnvydux	196	55	adaptive	adaptive	JJ
cord-320092-0qnvydux	196	56	immune	immune	JJ
cord-320092-0qnvydux	196	57	response	response	NN
cord-320092-0qnvydux	196	58	for	for	IN
cord-320092-0qnvydux	196	59	iron	iron	NN
cord-320092-0qnvydux	196	60	and	and	CC
cord-320092-0qnvydux	196	61	may	may	MD
cord-320092-0qnvydux	196	62	contribute	contribute	VB
cord-320092-0qnvydux	196	63	to	to	IN
cord-320092-0qnvydux	196	64	possible	possible	JJ
cord-320092-0qnvydux	196	65	T	T	NNP
cord-320092-0qnvydux	196	66	cell	cell	NN
cord-320092-0qnvydux	196	67	dysfunction	dysfunction	NN
cord-320092-0qnvydux	196	68	reported	report	VBN
cord-320092-0qnvydux	196	69	in	in	IN
cord-320092-0qnvydux	196	70	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	196	71	"	"	''
cord-320092-0qnvydux	196	72	[	[	-LRB-
cord-320092-0qnvydux	196	73	114	114	CD
cord-320092-0qnvydux	196	74	]	]	-RRB-
cord-320092-0qnvydux	196	75	.	.	.
cord-320092-0qnvydux	197	1	The	the	DT
cord-320092-0qnvydux	197	2	authors	author	NNS
cord-320092-0qnvydux	197	3	did	do	VBD
cord-320092-0qnvydux	197	4	not	not	RB
cord-320092-0qnvydux	197	5	find	find	VB
cord-320092-0qnvydux	197	6	significant	significant	JJ
cord-320092-0qnvydux	197	7	differences	difference	NNS
cord-320092-0qnvydux	197	8	in	in	IN
cord-320092-0qnvydux	197	9	transferrin	transferrin	NN
cord-320092-0qnvydux	197	10	saturation	saturation	NN
cord-320092-0qnvydux	197	11	or	or	CC
cord-320092-0qnvydux	197	12	serum	serum	NN
cord-320092-0qnvydux	197	13	ferritin	ferritin	NN
cord-320092-0qnvydux	197	14	levels	level	NNS
cord-320092-0qnvydux	197	15	between	between	IN
cord-320092-0qnvydux	197	16	the	the	DT
cord-320092-0qnvydux	197	17	nonsevere	nonsevere	JJ
cord-320092-0qnvydux	197	18	and	and	CC
cord-320092-0qnvydux	197	19	severe	severe	JJ
cord-320092-0qnvydux	197	20	hypoxemia	hypoxemia	NN
cord-320092-0qnvydux	197	21	patient	patient	NN
cord-320092-0qnvydux	197	22	groups	group	NNS
cord-320092-0qnvydux	197	23	.	.	.
cord-320092-0qnvydux	198	1	Congruently	Congruently	NNP
cord-320092-0qnvydux	198	2	,	,	,
cord-320092-0qnvydux	198	3	a	a	DT
cord-320092-0qnvydux	198	4	retrospective	retrospective	JJ
cord-320092-0qnvydux	198	5	study	study	NN
cord-320092-0qnvydux	198	6	of	of	IN
cord-320092-0qnvydux	198	7	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	198	8	patients	patient	NNS
cord-320092-0qnvydux	198	9	and	and	CC
cord-320092-0qnvydux	198	10	serum	serum	NN
cord-320092-0qnvydux	198	11	iron	iron	NN
cord-320092-0qnvydux	198	12	deficiency	deficiency	NN
cord-320092-0qnvydux	198	13	has	have	VBZ
cord-320092-0qnvydux	198	14	found	find	VBN
cord-320092-0qnvydux	198	15	that	that	IN
cord-320092-0qnvydux	198	16	"	"	``
cord-320092-0qnvydux	198	17	the	the	DT
cord-320092-0qnvydux	198	18	severity	severity	NN
cord-320092-0qnvydux	198	19	and	and	CC
cord-320092-0qnvydux	198	20	mortality	mortality	NN
cord-320092-0qnvydux	198	21	of	of	IN
cord-320092-0qnvydux	198	22	the	the	DT
cord-320092-0qnvydux	198	23	disease	disease	NN
cord-320092-0qnvydux	198	24	was	be	VBD
cord-320092-0qnvydux	198	25	closely	closely	RB
cord-320092-0qnvydux	198	26	correlated	correlate	VBN
cord-320092-0qnvydux	198	27	with	with	IN
cord-320092-0qnvydux	198	28	serum	serum	NN
cord-320092-0qnvydux	198	29	iron	iron	NN
cord-320092-0qnvydux	198	30	levels	level	NNS
cord-320092-0qnvydux	198	31	"	"	''
cord-320092-0qnvydux	198	32	[	[	-LRB-
cord-320092-0qnvydux	198	33	142	142	CD
cord-320092-0qnvydux	198	34	]	]	-RRB-
cord-320092-0qnvydux	198	35	.	.	.
cord-320092-0qnvydux	199	1	Beyond	beyond	IN
cord-320092-0qnvydux	199	2	the	the	DT
cord-320092-0qnvydux	199	3	immediate	immediate	JJ
cord-320092-0qnvydux	199	4	issue	issue	NN
cord-320092-0qnvydux	199	5	of	of	IN
cord-320092-0qnvydux	199	6	diagnostic	diagnostic	JJ
cord-320092-0qnvydux	199	7	markers	marker	NNS
cord-320092-0qnvydux	199	8	,	,	,
cord-320092-0qnvydux	199	9	two	two	CD
cord-320092-0qnvydux	199	10	broader	broad	JJR
cord-320092-0qnvydux	199	11	questions	question	NNS
cord-320092-0qnvydux	199	12	that	that	WDT
cord-320092-0qnvydux	199	13	could	could	MD
cord-320092-0qnvydux	199	14	follow	follow	VB
cord-320092-0qnvydux	199	15	from	from	IN
cord-320092-0qnvydux	199	16	the	the	DT
cord-320092-0qnvydux	199	17	present	present	JJ
cord-320092-0qnvydux	199	18	work	work	NN
cord-320092-0qnvydux	199	19	can	can	MD
cord-320092-0qnvydux	199	20	be	be	VB
cord-320092-0qnvydux	199	21	raised	raise	VBN
cord-320092-0qnvydux	199	22	:	:	:
cord-320092-0qnvydux	200	1	first	first	RB
cord-320092-0qnvydux	200	2	,	,	,
cord-320092-0qnvydux	200	3	does	do	VBZ
cord-320092-0qnvydux	200	4	the	the	DT
cord-320092-0qnvydux	200	5	spike	spike	NN
cord-320092-0qnvydux	200	6	protein	protein	NN
cord-320092-0qnvydux	200	7	,	,	,
cord-320092-0qnvydux	200	8	similar	similar	JJ
cord-320092-0qnvydux	200	9	to	to	IN
cord-320092-0qnvydux	200	10	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	200	11	,	,	,
cord-320092-0qnvydux	200	12	potentially	potentially	RB
cord-320092-0qnvydux	200	13	promote	promote	VB
cord-320092-0qnvydux	200	14	iron	iron	NN
cord-320092-0qnvydux	200	15	sequestration	sequestration	NN
cord-320092-0qnvydux	200	16	in	in	IN
cord-320092-0qnvydux	200	17	(	(	-LRB-
cord-320092-0qnvydux	200	18	alveolar	alveolar	NN
cord-320092-0qnvydux	200	19	)	)	-RRB-
cord-320092-0qnvydux	200	20	macrophages	macrophage	NNS
cord-320092-0qnvydux	200	21	[	[	-LRB-
cord-320092-0qnvydux	200	22	85	85	CD
cord-320092-0qnvydux	200	23	]	]	-RRB-
cord-320092-0qnvydux	200	24	and	and	CC
cord-320092-0qnvydux	200	25	hence	hence	RB
cord-320092-0qnvydux	200	26	impede	impede	VBP
cord-320092-0qnvydux	200	27	the	the	DT
cord-320092-0qnvydux	200	28	host	host	NN
cord-320092-0qnvydux	200	29	's	's	POS
cord-320092-0qnvydux	200	30	initial	initial	JJ
cord-320092-0qnvydux	200	31	immunological	immunological	JJ
cord-320092-0qnvydux	200	32	response	response	NN
cord-320092-0qnvydux	200	33	?	?	.
cord-320092-0qnvydux	201	1	Second	second	RB
cord-320092-0qnvydux	201	2	,	,	,
cord-320092-0qnvydux	201	3	could	could	MD
cord-320092-0qnvydux	201	4	reports	report	NNS
cord-320092-0qnvydux	201	5	of	of	IN
cord-320092-0qnvydux	201	6	the	the	DT
cord-320092-0qnvydux	201	7	common	common	JJ
cord-320092-0qnvydux	201	8	presence	presence	NN
cord-320092-0qnvydux	201	9	of	of	IN
cord-320092-0qnvydux	201	10	digestive	digestive	JJ
cord-320092-0qnvydux	201	11	symptoms	symptom	NNS
cord-320092-0qnvydux	201	12	in	in	IN
cord-320092-0qnvydux	201	13	COVID-19	covid-19	JJ
cord-320092-0qnvydux	201	14	patients	patient	NNS
cord-320092-0qnvydux	201	15	(	(	-LRB-
cord-320092-0qnvydux	201	16	e.g.	e.g.	RB
cord-320092-0qnvydux	201	17	,	,	,
cord-320092-0qnvydux	201	18	ref	ref	NN
cord-320092-0qnvydux	201	19	.	.	.
cord-320092-0qnvydux	202	1	[	[	-LRB-
cord-320092-0qnvydux	202	2	95	95	CD
cord-320092-0qnvydux	202	3	]	]	-RRB-
cord-320092-0qnvydux	202	4	)	)	-RRB-
cord-320092-0qnvydux	202	5	be	be	VB
cord-320092-0qnvydux	202	6	explainable	explainable	JJ
cord-320092-0qnvydux	202	7	in	in	IN
cord-320092-0qnvydux	202	8	part	part	NN
cord-320092-0qnvydux	202	9	by	by	IN
cord-320092-0qnvydux	202	10	a	a	DT
cord-320092-0qnvydux	202	11	link	link	NN
cord-320092-0qnvydux	202	12	to	to	IN
cord-320092-0qnvydux	202	13	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	202	14	?	?	.
cord-320092-0qnvydux	203	1	With	with	IN
cord-320092-0qnvydux	203	2	respect	respect	NN
cord-320092-0qnvydux	203	3	to	to	IN
cord-320092-0qnvydux	203	4	the	the	DT
cord-320092-0qnvydux	203	5	biology	biology	NN
cord-320092-0qnvydux	203	6	surrounding	surround	VBG
cord-320092-0qnvydux	203	7	these	these	DT
cord-320092-0qnvydux	203	8	gastrointestinal	gastrointestinal	JJ
cord-320092-0qnvydux	203	9	symptoms	symptom	NNS
cord-320092-0qnvydux	203	10	,	,	,
cord-320092-0qnvydux	203	11	it	-PRON-	PRP
cord-320092-0qnvydux	203	12	is	be	VBZ
cord-320092-0qnvydux	203	13	important	important	JJ
cord-320092-0qnvydux	203	14	to	to	TO
cord-320092-0qnvydux	203	15	point	point	VB
cord-320092-0qnvydux	203	16	out	out	RP
cord-320092-0qnvydux	203	17	that	that	IN
cord-320092-0qnvydux	203	18	a	a	DT
cord-320092-0qnvydux	203	19	recent	recent	JJ
cord-320092-0qnvydux	203	20	study	study	NN
cord-320092-0qnvydux	203	21	concluded	conclude	VBD
cord-320092-0qnvydux	203	22	that	that	IN
cord-320092-0qnvydux	203	23	in	in	IN
cord-320092-0qnvydux	203	24	gut	gut	NN
cord-320092-0qnvydux	203	25	epithelial	epithelial	JJ
cord-320092-0qnvydux	203	26	cells	cell	NNS
cord-320092-0qnvydux	203	27	,	,	,
cord-320092-0qnvydux	203	28	the	the	DT
cord-320092-0qnvydux	203	29	"	"	``
cord-320092-0qnvydux	203	30	expression	expression	NN
cord-320092-0qnvydux	203	31	of	of	IN
cord-320092-0qnvydux	203	32	two	two	CD
cord-320092-0qnvydux	203	33	mucosaspecific	mucosaspecific	JJ
cord-320092-0qnvydux	203	34	serine	serine	NN
cord-320092-0qnvydux	203	35	proteases	protease	NNS
cord-320092-0qnvydux	203	36	,	,	,
cord-320092-0qnvydux	203	37	TMPRSS2	TMPRSS2	NNP
cord-320092-0qnvydux	203	38	and	and	CC
cord-320092-0qnvydux	203	39	TMPRSS4	TMPRSS4	NNP
cord-320092-0qnvydux	203	40	,	,	,
cord-320092-0qnvydux	203	41	facilitated	facilitate	VBD
cord-320092-0qnvydux	203	42	SARS	SARS	NNP
cord-320092-0qnvydux	203	43	-	-	HYPH
cord-320092-0qnvydux	203	44	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	203	45	spike	spike	NN
cord-320092-0qnvydux	203	46	fusogenic	fusogenic	JJ
cord-320092-0qnvydux	203	47	activity	activity	NN
cord-320092-0qnvydux	203	48	and	and	CC
cord-320092-0qnvydux	203	49	promoted	promote	VBD
cord-320092-0qnvydux	203	50	virus	virus	NN
cord-320092-0qnvydux	203	51	entry	entry	NN
cord-320092-0qnvydux	203	52	into	into	IN
cord-320092-0qnvydux	203	53	host	host	NN
cord-320092-0qnvydux	203	54	cells	cell	NNS
cord-320092-0qnvydux	203	55	"	"	''
cord-320092-0qnvydux	203	56	[	[	-LRB-
cord-320092-0qnvydux	203	57	140	140	CD
cord-320092-0qnvydux	203	58	]	]	-RRB-
cord-320092-0qnvydux	203	59	.	.	.
cord-320092-0qnvydux	204	1	It	-PRON-	PRP
cord-320092-0qnvydux	204	2	is	be	VBZ
cord-320092-0qnvydux	204	3	also	also	RB
cord-320092-0qnvydux	204	4	known	know	VBN
cord-320092-0qnvydux	204	5	that	that	IN
cord-320092-0qnvydux	204	6	the	the	DT
cord-320092-0qnvydux	204	7	liver	liver	NN
cord-320092-0qnvydux	204	8	-	-	HYPH
cord-320092-0qnvydux	204	9	specific	specific	JJ
cord-320092-0qnvydux	204	10	serine	serine	NN
cord-320092-0qnvydux	204	11	protease	protease	NN
cord-320092-0qnvydux	204	12	TMPRSS6	tmprss6	XX
cord-320092-0qnvydux	205	1	(	(	-LRB-
cord-320092-0qnvydux	205	2	matriptase-2	matriptase-2	NNP
cord-320092-0qnvydux	205	3	)	)	-RRB-
cord-320092-0qnvydux	205	4	negatively	negatively	RB
cord-320092-0qnvydux	205	5	modulates	modulate	VBZ
cord-320092-0qnvydux	205	6	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	205	7	[	[	-LRB-
cord-320092-0qnvydux	205	8	16	16	CD
cord-320092-0qnvydux	205	9	,	,	,
cord-320092-0qnvydux	205	10	22	22	CD
cord-320092-0qnvydux	205	11	,	,	,
cord-320092-0qnvydux	205	12	36	36	CD
cord-320092-0qnvydux	205	13	]	]	-RRB-
cord-320092-0qnvydux	205	14	.	.	.
cord-320092-0qnvydux	206	1	Again	again	RB
cord-320092-0qnvydux	206	2	,	,	,
cord-320092-0qnvydux	206	3	what	what	WP
cord-320092-0qnvydux	206	4	if	if	IN
cord-320092-0qnvydux	206	5	any	any	DT
cord-320092-0qnvydux	206	6	significance	significance	NN
cord-320092-0qnvydux	206	7	these	these	DT
cord-320092-0qnvydux	206	8	connections	connection	NNS
cord-320092-0qnvydux	206	9	might	may	MD
cord-320092-0qnvydux	206	10	hold	hold	VB
cord-320092-0qnvydux	206	11	remains	remain	NNS
cord-320092-0qnvydux	206	12	to	to	TO
cord-320092-0qnvydux	206	13	be	be	VB
cord-320092-0qnvydux	206	14	determined	determine	VBN
cord-320092-0qnvydux	206	15	.	.	.
cord-320092-0qnvydux	207	1	Overall	overall	RB
cord-320092-0qnvydux	207	2	,	,	,
cord-320092-0qnvydux	207	3	the	the	DT
cord-320092-0qnvydux	207	4	observations	observation	NNS
cord-320092-0qnvydux	207	5	in	in	IN
cord-320092-0qnvydux	207	6	this	this	DT
cord-320092-0qnvydux	207	7	report	report	NN
cord-320092-0qnvydux	207	8	suggest	suggest	VBP
cord-320092-0qnvydux	207	9	that	that	IN
cord-320092-0qnvydux	207	10	,	,	,
cord-320092-0qnvydux	207	11	as	as	IN
cord-320092-0qnvydux	207	12	a	a	DT
cord-320092-0qnvydux	207	13	starting	starting	NN
cord-320092-0qnvydux	207	14	point	point	NN
cord-320092-0qnvydux	207	15	,	,	,
cord-320092-0qnvydux	207	16	serum	serum	NN
cord-320092-0qnvydux	207	17	iron	iron	NN
cord-320092-0qnvydux	207	18	status	status	NN
cord-320092-0qnvydux	207	19	would	would	MD
cord-320092-0qnvydux	207	20	be	be	VB
cord-320092-0qnvydux	207	21	a	a	DT
cord-320092-0qnvydux	207	22	critical	critical	JJ
cord-320092-0qnvydux	207	23	data	data	NN
cord-320092-0qnvydux	207	24	category	category	NN
cord-320092-0qnvydux	207	25	to	to	TO
cord-320092-0qnvydux	207	26	be	be	VB
cord-320092-0qnvydux	207	27	systematically	systematically	RB
cord-320092-0qnvydux	207	28	collected	collect	VBN
cord-320092-0qnvydux	207	29	from	from	IN
cord-320092-0qnvydux	207	30	patients	patient	NNS
cord-320092-0qnvydux	207	31	at	at	IN
cord-320092-0qnvydux	207	32	various	various	JJ
cord-320092-0qnvydux	207	33	stages	stage	NNS
cord-320092-0qnvydux	207	34	of	of	IN
cord-320092-0qnvydux	207	35	the	the	DT
cord-320092-0qnvydux	207	36	disease	disease	NN
cord-320092-0qnvydux	207	37	's	's	POS
cord-320092-0qnvydux	207	38	progression	progression	NN
cord-320092-0qnvydux	207	39	.	.	.
cord-320092-0qnvydux	208	1	Furthermore	furthermore	RB
cord-320092-0qnvydux	208	2	,	,	,
cord-320092-0qnvydux	208	3	iron	iron	NN
cord-320092-0qnvydux	208	4	dyshomeostasis	dyshomeostasis	NN
cord-320092-0qnvydux	208	5	in	in	IN
cord-320092-0qnvydux	208	6	the	the	DT
cord-320092-0qnvydux	208	7	case	case	NN
cord-320092-0qnvydux	208	8	of	of	IN
cord-320092-0qnvydux	208	9	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	208	10	may	may	MD
cord-320092-0qnvydux	208	11	be	be	VB
cord-320092-0qnvydux	208	12	a	a	DT
cord-320092-0qnvydux	208	13	more	more	RBR
cord-320092-0qnvydux	208	14	specific	specific	JJ
cord-320092-0qnvydux	208	15	pathobiological	pathobiological	JJ
cord-320092-0qnvydux	208	16	feature	feature	NN
cord-320092-0qnvydux	208	17	of	of	IN
cord-320092-0qnvydux	208	18	this	this	DT
cord-320092-0qnvydux	208	19	infection	infection	NN
cord-320092-0qnvydux	208	20	,	,	,
cord-320092-0qnvydux	208	21	and	and	CC
cord-320092-0qnvydux	208	22	we	-PRON-	PRP
cord-320092-0qnvydux	208	23	can	can	MD
cord-320092-0qnvydux	208	24	only	only	RB
cord-320092-0qnvydux	208	25	know	know	VB
cord-320092-0qnvydux	208	26	the	the	DT
cord-320092-0qnvydux	208	27	answer	answer	NN
cord-320092-0qnvydux	208	28	to	to	IN
cord-320092-0qnvydux	208	29	this	this	DT
cord-320092-0qnvydux	208	30	scenario	scenario	NN
cord-320092-0qnvydux	208	31	if	if	IN
cord-320092-0qnvydux	208	32	more	more	JJR
cord-320092-0qnvydux	208	33	data	datum	NNS
cord-320092-0qnvydux	208	34	related	relate	VBN
cord-320092-0qnvydux	208	35	to	to	IN
cord-320092-0qnvydux	208	36	iron	iron	NN
cord-320092-0qnvydux	208	37	biology	biology	NN
cord-320092-0qnvydux	208	38	is	be	VBZ
cord-320092-0qnvydux	208	39	collected	collect	VBN
cord-320092-0qnvydux	208	40	during	during	IN
cord-320092-0qnvydux	208	41	the	the	DT
cord-320092-0qnvydux	208	42	current	current	JJ
cord-320092-0qnvydux	208	43	pandemic	pandemic	NN
cord-320092-0qnvydux	208	44	.	.	.
cord-320092-0qnvydux	209	1	Could	Could	MD
cord-320092-0qnvydux	209	2	,	,	,
cord-320092-0qnvydux	209	3	for	for	IN
cord-320092-0qnvydux	209	4	instance	instance	NN
cord-320092-0qnvydux	209	5	,	,	,
cord-320092-0qnvydux	209	6	clinical	clinical	JJ
cord-320092-0qnvydux	209	7	evidence	evidence	NN
cord-320092-0qnvydux	209	8	be	be	VB
cord-320092-0qnvydux	209	9	gathered	gather	VBN
cord-320092-0qnvydux	209	10	to	to	TO
cord-320092-0qnvydux	209	11	clarify	clarify	VB
cord-320092-0qnvydux	209	12	if	if	IN
cord-320092-0qnvydux	209	13	disorders	disorder	NNS
cord-320092-0qnvydux	209	14	of	of	IN
cord-320092-0qnvydux	209	15	iron	iron	NN
cord-320092-0qnvydux	209	16	homeostasis	homeostasis	NN
cord-320092-0qnvydux	209	17	might	may	MD
cord-320092-0qnvydux	209	18	exacerbate	exacerbate	VB
cord-320092-0qnvydux	209	19	symptoms	symptom	NNS
cord-320092-0qnvydux	209	20	in	in	IN
cord-320092-0qnvydux	209	21	COVID-19	covid-19	JJ
cord-320092-0qnvydux	209	22	patients	patient	NNS
cord-320092-0qnvydux	209	23	?	?	.
cord-320092-0qnvydux	210	1	As	as	IN
cord-320092-0qnvydux	210	2	a	a	DT
cord-320092-0qnvydux	210	3	final	final	JJ
cord-320092-0qnvydux	210	4	note	note	NN
cord-320092-0qnvydux	210	5	,	,	,
cord-320092-0qnvydux	210	6	given	give	VBN
cord-320092-0qnvydux	210	7	the	the	DT
cord-320092-0qnvydux	210	8	many	many	JJ
cord-320092-0qnvydux	210	9	known	know	VBN
cord-320092-0qnvydux	210	10	and	and	CC
cord-320092-0qnvydux	210	11	yetto	yetto	NN
cord-320092-0qnvydux	210	12	-	-	HYPH
cord-320092-0qnvydux	210	13	be	be	VB
cord-320092-0qnvydux	210	14	-	-	HYPH
cord-320092-0qnvydux	210	15	discovered	discover	VBN
cord-320092-0qnvydux	210	16	intricacies	intricacy	NNS
cord-320092-0qnvydux	210	17	of	of	IN
cord-320092-0qnvydux	210	18	iron	iron	NN
cord-320092-0qnvydux	210	19	homeostasis	homeostasis	NN
cord-320092-0qnvydux	210	20	in	in	IN
cord-320092-0qnvydux	210	21	the	the	DT
cord-320092-0qnvydux	210	22	body	body	NN
cord-320092-0qnvydux	210	23	,	,	,
cord-320092-0qnvydux	210	24	research	research	NN
cord-320092-0qnvydux	210	25	on	on	IN
cord-320092-0qnvydux	210	26	therapeutic	therapeutic	JJ
cord-320092-0qnvydux	210	27	strategies	strategy	NNS
cord-320092-0qnvydux	210	28	that	that	WDT
cord-320092-0qnvydux	210	29	,	,	,
cord-320092-0qnvydux	210	30	for	for	IN
cord-320092-0qnvydux	210	31	example	example	NN
cord-320092-0qnvydux	210	32	,	,	,
cord-320092-0qnvydux	210	33	propose	propose	VB
cord-320092-0qnvydux	210	34	to	to	TO
cord-320092-0qnvydux	210	35	utilize	utilize	VB
cord-320092-0qnvydux	210	36	iron	iron	NN
cord-320092-0qnvydux	210	37	chelation	chelation	NN
cord-320092-0qnvydux	210	38	or	or	CC
cord-320092-0qnvydux	210	39	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	210	40	antagonists	antagonist	NNS
cord-320092-0qnvydux	210	41	should	should	MD
cord-320092-0qnvydux	210	42	proceed	proceed	VB
cord-320092-0qnvydux	210	43	cautiously	cautiously	RB
cord-320092-0qnvydux	210	44	[	[	-LRB-
cord-320092-0qnvydux	210	45	1	1	CD
cord-320092-0qnvydux	210	46	,	,	,
cord-320092-0qnvydux	210	47	52	52	CD
cord-320092-0qnvydux	210	48	]	]	-RRB-
cord-320092-0qnvydux	210	49	.	.	.
cord-320092-0qnvydux	211	1	Theoretical	theoretical	JJ
cord-320092-0qnvydux	211	2	analyses	analysis	NNS
cord-320092-0qnvydux	211	3	in	in	IN
cord-320092-0qnvydux	211	4	new	new	JJ
cord-320092-0qnvydux	211	5	areas	area	NNS
cord-320092-0qnvydux	211	6	may	may	MD
cord-320092-0qnvydux	211	7	necessarily	necessarily	RB
cord-320092-0qnvydux	211	8	entail	entail	VB
cord-320092-0qnvydux	211	9	reasonable	reasonable	JJ
cord-320092-0qnvydux	211	10	speculations	speculation	NNS
cord-320092-0qnvydux	211	11	based	base	VBN
cord-320092-0qnvydux	211	12	on	on	IN
cord-320092-0qnvydux	211	13	limited	limited	JJ
cord-320092-0qnvydux	211	14	or	or	CC
cord-320092-0qnvydux	211	15	disparate	disparate	JJ
cord-320092-0qnvydux	211	16	data	datum	NNS
cord-320092-0qnvydux	211	17	.	.	.
cord-320092-0qnvydux	212	1	This	this	DT
cord-320092-0qnvydux	212	2	is	be	VBZ
cord-320092-0qnvydux	212	3	expected	expect	VBN
cord-320092-0qnvydux	212	4	,	,	,
cord-320092-0qnvydux	212	5	but	but	CC
cord-320092-0qnvydux	212	6	one	one	PRP
cord-320092-0qnvydux	212	7	should	should	MD
cord-320092-0qnvydux	212	8	remain	remain	VB
cord-320092-0qnvydux	212	9	cognizant	cognizant	JJ
cord-320092-0qnvydux	212	10	of	of	IN
cord-320092-0qnvydux	212	11	overinterpretation	overinterpretation	NN
cord-320092-0qnvydux	212	12	,	,	,
cord-320092-0qnvydux	212	13	and	and	CC
cord-320092-0qnvydux	212	14	pursue	pursue	VB
cord-320092-0qnvydux	212	15	a	a	DT
cord-320092-0qnvydux	212	16	rational	rational	JJ
cord-320092-0qnvydux	212	17	course	course	NN
cord-320092-0qnvydux	212	18	of	of	IN
cord-320092-0qnvydux	212	19	theoretical	theoretical	JJ
cord-320092-0qnvydux	212	20	inquiry	inquiry	NN
cord-320092-0qnvydux	212	21	to	to	TO
cord-320092-0qnvydux	212	22	hopefully	hopefully	RB
cord-320092-0qnvydux	212	23	inform	inform	VB
cord-320092-0qnvydux	212	24	subsequent	subsequent	JJ
cord-320092-0qnvydux	212	25	experimental	experimental	JJ
cord-320092-0qnvydux	212	26	investigations	investigation	NNS
cord-320092-0qnvydux	212	27	.	.	.
cord-320092-0qnvydux	213	1	Here	here	RB
cord-320092-0qnvydux	213	2	,	,	,
cord-320092-0qnvydux	213	3	a	a	DT
cord-320092-0qnvydux	213	4	purposeful	purposeful	JJ
cord-320092-0qnvydux	213	5	and	and	CC
cord-320092-0qnvydux	213	6	restricted	restricted	JJ
cord-320092-0qnvydux	213	7	protein	protein	NN
cord-320092-0qnvydux	213	8	sequence	sequence	NN
cord-320092-0qnvydux	213	9	search	search	NN
cord-320092-0qnvydux	213	10	revealed	reveal	VBD
cord-320092-0qnvydux	213	11	a	a	DT
cord-320092-0qnvydux	213	12	potential	potential	JJ
cord-320092-0qnvydux	213	13	sequence	sequence	NN
cord-320092-0qnvydux	213	14	similarity	similarity	NN
cord-320092-0qnvydux	213	15	between	between	IN
cord-320092-0qnvydux	213	16	the	the	DT
cord-320092-0qnvydux	213	17	relatively	relatively	RB
cord-320092-0qnvydux	213	18	less	less	RBR
cord-320092-0qnvydux	213	19	-	-	HYPH
cord-320092-0qnvydux	213	20	studied	study	VBN
cord-320092-0qnvydux	213	21	cysteine	cysteine	NN
cord-320092-0qnvydux	213	22	-	-	HYPH
cord-320092-0qnvydux	213	23	rich	rich	JJ
cord-320092-0qnvydux	213	24	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	213	25	domain	domain	NN
cord-320092-0qnvydux	213	26	of	of	IN
cord-320092-0qnvydux	213	27	coronavirus	coronavirus	NN
cord-320092-0qnvydux	213	28	spike	spike	NN
cord-320092-0qnvydux	213	29	proteins	protein	NNS
cord-320092-0qnvydux	213	30	and	and	CC
cord-320092-0qnvydux	213	31	the	the	DT
cord-320092-0qnvydux	213	32	vertebrate	vertebrate	JJ
cord-320092-0qnvydux	213	33	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	213	34	protein	protein	NN
cord-320092-0qnvydux	213	35	.	.	.
cord-320092-0qnvydux	214	1	This	this	DT
cord-320092-0qnvydux	214	2	is	be	VBZ
cord-320092-0qnvydux	214	3	quite	quite	RB
cord-320092-0qnvydux	214	4	unlikely	unlikely	JJ
cord-320092-0qnvydux	214	5	to	to	TO
cord-320092-0qnvydux	214	6	be	be	VB
cord-320092-0qnvydux	214	7	a	a	DT
cord-320092-0qnvydux	214	8	spurious	spurious	JJ
cord-320092-0qnvydux	214	9	and	and	CC
cord-320092-0qnvydux	214	10	random	random	JJ
cord-320092-0qnvydux	214	11	similarity	similarity	NN
cord-320092-0qnvydux	214	12	.	.	.
cord-320092-0qnvydux	215	1	There	there	EX
cord-320092-0qnvydux	215	2	are	be	VBP
cord-320092-0qnvydux	215	3	many	many	JJ
cord-320092-0qnvydux	215	4	cysteine	cysteine	JJ
cord-320092-0qnvydux	215	5	-	-	HYPH
cord-320092-0qnvydux	215	6	rich	rich	JJ
cord-320092-0qnvydux	215	7	protein	protein	NN
cord-320092-0qnvydux	215	8	sequences	sequence	NNS
cord-320092-0qnvydux	215	9	in	in	IN
cord-320092-0qnvydux	215	10	vertebrates	vertebrate	NNS
cord-320092-0qnvydux	215	11	,	,	,
cord-320092-0qnvydux	215	12	but	but	CC
cord-320092-0qnvydux	215	13	the	the	DT
cord-320092-0qnvydux	215	14	motif	motif	NN
cord-320092-0qnvydux	215	15	identified	identify	VBN
cord-320092-0qnvydux	215	16	here	here	RB
cord-320092-0qnvydux	215	17	is	be	VBZ
cord-320092-0qnvydux	215	18	unique	unique	JJ
cord-320092-0qnvydux	215	19	and	and	CC
cord-320092-0qnvydux	215	20	specific	specific	JJ
cord-320092-0qnvydux	215	21	,	,	,
cord-320092-0qnvydux	215	22	and	and	CC
cord-320092-0qnvydux	215	23	also	also	RB
cord-320092-0qnvydux	215	24	appears	appear	VBZ
cord-320092-0qnvydux	215	25	to	to	TO
cord-320092-0qnvydux	215	26	tentatively	tentatively	RB
cord-320092-0qnvydux	215	27	set	set	VB
cord-320092-0qnvydux	215	28	apart	apart	RP
cord-320092-0qnvydux	215	29	the	the	DT
cord-320092-0qnvydux	215	30	disease	disease	NN
cord-320092-0qnvydux	215	31	-	-	HYPH
cord-320092-0qnvydux	215	32	causing	cause	VBG
cord-320092-0qnvydux	215	33	strains	strain	NNS
cord-320092-0qnvydux	215	34	from	from	IN
cord-320092-0qnvydux	215	35	the	the	DT
cord-320092-0qnvydux	215	36	milder	mild	JJR
cord-320092-0qnvydux	215	37	coronavirus	coronavirus	NN
cord-320092-0qnvydux	215	38	strains	strain	NNS
cord-320092-0qnvydux	215	39	.	.	.
cord-320092-0qnvydux	216	1	Following	follow	VBG
cord-320092-0qnvydux	216	2	from	from	IN
cord-320092-0qnvydux	216	3	this	this	DT
cord-320092-0qnvydux	216	4	link	link	NN
cord-320092-0qnvydux	216	5	,	,	,
cord-320092-0qnvydux	216	6	a	a	DT
cord-320092-0qnvydux	216	7	number	number	NN
cord-320092-0qnvydux	216	8	of	of	IN
cord-320092-0qnvydux	216	9	emerging	emerge	VBG
cord-320092-0qnvydux	216	10	clinical	clinical	JJ
cord-320092-0qnvydux	216	11	strands	strand	NNS
cord-320092-0qnvydux	216	12	of	of	IN
cord-320092-0qnvydux	216	13	evidence	evidence	NN
cord-320092-0qnvydux	216	14	(	(	-LRB-
cord-320092-0qnvydux	216	15	summarized	summarize	VBN
cord-320092-0qnvydux	216	16	in	in	IN
cord-320092-0qnvydux	216	17	Table	Table	NNP
cord-320092-0qnvydux	216	18	1	1	CD
cord-320092-0qnvydux	216	19	)	)	-RRB-
cord-320092-0qnvydux	216	20	were	be	VBD
cord-320092-0qnvydux	216	21	discussed	discuss	VBN
cord-320092-0qnvydux	216	22	which	which	WDT
cord-320092-0qnvydux	216	23	further	further	RB
cord-320092-0qnvydux	216	24	link	link	VBP
cord-320092-0qnvydux	216	25	a	a	DT
cord-320092-0qnvydux	216	26	biology	biology	NN
cord-320092-0qnvydux	216	27	surrounding	surround	VBG
cord-320092-0qnvydux	216	28	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	216	29	with	with	IN
cord-320092-0qnvydux	216	30	coronavirus	coronavirus	NN
cord-320092-0qnvydux	216	31	-	-	HYPH
cord-320092-0qnvydux	216	32	caused	cause	VBN
cord-320092-0qnvydux	216	33	pathobiology	pathobiology	NN
cord-320092-0qnvydux	216	34	.	.	.
cord-320092-0qnvydux	217	1	While	while	IN
cord-320092-0qnvydux	217	2	each	each	DT
cord-320092-0qnvydux	217	3	piece	piece	NN
cord-320092-0qnvydux	217	4	of	of	IN
cord-320092-0qnvydux	217	5	clinical	clinical	JJ
cord-320092-0qnvydux	217	6	evidence	evidence	NN
cord-320092-0qnvydux	217	7	discussed	discuss	VBD
cord-320092-0qnvydux	217	8	does	do	VBZ
cord-320092-0qnvydux	217	9	not	not	RB
cord-320092-0qnvydux	217	10	by	by	IN
cord-320092-0qnvydux	217	11	itself	-PRON-	PRP
cord-320092-0qnvydux	217	12	provide	provide	VB
cord-320092-0qnvydux	217	13	overwhelming	overwhelming	JJ
cord-320092-0qnvydux	217	14	corroboration	corroboration	NN
cord-320092-0qnvydux	217	15	for	for	IN
cord-320092-0qnvydux	217	16	the	the	DT
cord-320092-0qnvydux	217	17	hypothesis	hypothesis	NN
cord-320092-0qnvydux	217	18	of	of	IN
cord-320092-0qnvydux	217	19	the	the	DT
cord-320092-0qnvydux	217	20	paper	paper	NN
cord-320092-0qnvydux	217	21	,	,	,
cord-320092-0qnvydux	217	22	the	the	DT
cord-320092-0qnvydux	217	23	totality	totality	NN
cord-320092-0qnvydux	217	24	of	of	IN
cord-320092-0qnvydux	217	25	evidence	evidence	NN
cord-320092-0qnvydux	217	26	presented	present	VBN
cord-320092-0qnvydux	217	27	we	-PRON-	PRP
cord-320092-0qnvydux	217	28	believe	believe	VBP
cord-320092-0qnvydux	217	29	make	make	VBP
cord-320092-0qnvydux	217	30	a	a	DT
cord-320092-0qnvydux	217	31	strong	strong	JJ
cord-320092-0qnvydux	217	32	case	case	NN
cord-320092-0qnvydux	217	33	that	that	IN
cord-320092-0qnvydux	217	34	if	if	IN
cord-320092-0qnvydux	217	35	sequence	sequence	NN
cord-320092-0qnvydux	217	36	and/or	and/or	CC
cord-320092-0qnvydux	217	37	structural	structural	JJ
cord-320092-0qnvydux	217	38	mimicry	mimicry	NN
cord-320092-0qnvydux	217	39	to	to	IN
cord-320092-0qnvydux	217	40	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	217	41	is	be	VBZ
cord-320092-0qnvydux	217	42	taking	take	VBG
cord-320092-0qnvydux	217	43	place	place	NN
cord-320092-0qnvydux	217	44	upon	upon	IN
cord-320092-0qnvydux	217	45	viral	viral	JJ
cord-320092-0qnvydux	217	46	attachment	attachment	NN
cord-320092-0qnvydux	217	47	to	to	IN
cord-320092-0qnvydux	217	48	and	and	CC
cord-320092-0qnvydux	217	49	entry	entry	NN
cord-320092-0qnvydux	217	50	in	in	IN
cord-320092-0qnvydux	217	51	the	the	DT
cord-320092-0qnvydux	217	52	host	host	NN
cord-320092-0qnvydux	217	53	cell	cell	NN
cord-320092-0qnvydux	217	54	,	,	,
cord-320092-0qnvydux	217	55	then	then	RB
cord-320092-0qnvydux	217	56	perhaps	perhaps	RB
cord-320092-0qnvydux	217	57	a	a	DT
cord-320092-0qnvydux	217	58	local	local	JJ
cord-320092-0qnvydux	217	59	disease	disease	NN
cord-320092-0qnvydux	217	60	condition	condition	NN
cord-320092-0qnvydux	217	61	resembling	resemble	VBG
cord-320092-0qnvydux	217	62	iron	iron	NN
cord-320092-0qnvydux	217	63	dysregulation	dysregulation	NN
cord-320092-0qnvydux	217	64	(	(	-LRB-
cord-320092-0qnvydux	217	65	e.g.	e.g.	RB
cord-320092-0qnvydux	217	66	,	,	,
cord-320092-0qnvydux	217	67	iron	iron	NN
cord-320092-0qnvydux	217	68	overload	overload	NN
cord-320092-0qnvydux	217	69	)	)	-RRB-
cord-320092-0qnvydux	217	70	might	may	MD
cord-320092-0qnvydux	217	71	ensue	ensue	VB
cord-320092-0qnvydux	217	72	in	in	IN
cord-320092-0qnvydux	217	73	the	the	DT
cord-320092-0qnvydux	217	74	infected	infected	JJ
cord-320092-0qnvydux	217	75	tissue(s	tissue(s	NN
cord-320092-0qnvydux	217	76	)	)	-RRB-
cord-320092-0qnvydux	217	77	.	.	.
cord-320092-0qnvydux	218	1	This	this	DT
cord-320092-0qnvydux	218	2	hypothesis	hypothesis	NN
cord-320092-0qnvydux	218	3	can	can	MD
cord-320092-0qnvydux	218	4	be	be	VB
cord-320092-0qnvydux	218	5	immediately	immediately	RB
cord-320092-0qnvydux	218	6	tested	test	VBN
cord-320092-0qnvydux	218	7	in	in	IN
cord-320092-0qnvydux	218	8	one	one	CD
cord-320092-0qnvydux	218	9	of	of	IN
cord-320092-0qnvydux	218	10	three	three	CD
cord-320092-0qnvydux	218	11	ways	way	NNS
cord-320092-0qnvydux	218	12	.	.	.
cord-320092-0qnvydux	219	1	First	first	RB
cord-320092-0qnvydux	219	2	,	,	,
cord-320092-0qnvydux	219	3	in	in	IN
cord-320092-0qnvydux	219	4	the	the	DT
cord-320092-0qnvydux	219	5	clinic	clinic	NN
cord-320092-0qnvydux	219	6	,	,	,
cord-320092-0qnvydux	219	7	levels	level	NNS
cord-320092-0qnvydux	219	8	of	of	IN
cord-320092-0qnvydux	219	9	various	various	JJ
cord-320092-0qnvydux	219	10	serum	serum	NN
cord-320092-0qnvydux	219	11	markers	marker	NNS
cord-320092-0qnvydux	219	12	for	for	IN
cord-320092-0qnvydux	219	13	iron	iron	NN
cord-320092-0qnvydux	219	14	biology	biology	NN
cord-320092-0qnvydux	219	15	could	could	MD
cord-320092-0qnvydux	219	16	be	be	VB
cord-320092-0qnvydux	219	17	more	more	RBR
cord-320092-0qnvydux	219	18	systematically	systematically	RB
cord-320092-0qnvydux	219	19	and	and	CC
cord-320092-0qnvydux	219	20	comprehensively	comprehensively	RB
cord-320092-0qnvydux	219	21	measured	measure	VBN
cord-320092-0qnvydux	219	22	and	and	CC
cord-320092-0qnvydux	219	23	analyzed	analyze	VBD
cord-320092-0qnvydux	219	24	.	.	.
cord-320092-0qnvydux	220	1	This	this	DT
cord-320092-0qnvydux	220	2	strand	strand	NN
cord-320092-0qnvydux	220	3	of	of	IN
cord-320092-0qnvydux	220	4	investigation	investigation	NN
cord-320092-0qnvydux	220	5	has	have	VBZ
cord-320092-0qnvydux	220	6	already	already	RB
cord-320092-0qnvydux	220	7	produced	produce	VBN
cord-320092-0qnvydux	220	8	corroborating	corroborate	VBG
cord-320092-0qnvydux	220	9	evidence	evidence	NN
cord-320092-0qnvydux	220	10	in	in	IN
cord-320092-0qnvydux	220	11	the	the	DT
cord-320092-0qnvydux	220	12	form	form	NN
cord-320092-0qnvydux	220	13	of	of	IN
cord-320092-0qnvydux	220	14	increased	increase	VBN
cord-320092-0qnvydux	220	15	serum	serum	NN
cord-320092-0qnvydux	220	16	levels	level	NNS
cord-320092-0qnvydux	220	17	of	of	IN
cord-320092-0qnvydux	220	18	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	220	19	and	and	CC
cord-320092-0qnvydux	220	20	significantly	significantly	RB
cord-320092-0qnvydux	220	21	lower	low	JJR
cord-320092-0qnvydux	220	22	levels	level	NNS
cord-320092-0qnvydux	220	23	of	of	IN
cord-320092-0qnvydux	220	24	serum	serum	NN
cord-320092-0qnvydux	220	25	iron	iron	NN
cord-320092-0qnvydux	220	26	in	in	IN
cord-320092-0qnvydux	220	27	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	220	28	patients	patient	NNS
cord-320092-0qnvydux	220	29	.	.	.
cord-320092-0qnvydux	221	1	Second	second	JJ
cord-320092-0qnvydux	221	2	,	,	,
cord-320092-0qnvydux	221	3	computational	computational	JJ
cord-320092-0qnvydux	221	4	investigations	investigation	NNS
cord-320092-0qnvydux	221	5	could	could	MD
cord-320092-0qnvydux	221	6	examine	examine	VB
cord-320092-0qnvydux	221	7	potential	potential	JJ
cord-320092-0qnvydux	221	8	structural	structural	JJ
cord-320092-0qnvydux	221	9	mimicry	mimicry	NN
cord-320092-0qnvydux	221	10	between	between	IN
cord-320092-0qnvydux	221	11	the	the	DT
cord-320092-0qnvydux	221	12	two	two	CD
cord-320092-0qnvydux	221	13	proteins	protein	NNS
cord-320092-0qnvydux	221	14	and	and	CC
cord-320092-0qnvydux	221	15	explore	explore	VB
cord-320092-0qnvydux	221	16	the	the	DT
cord-320092-0qnvydux	221	17	effect	effect	NN
cord-320092-0qnvydux	221	18	of	of	IN
cord-320092-0qnvydux	221	19	differing	differ	VBG
cord-320092-0qnvydux	221	20	post	post	JJ
cord-320092-0qnvydux	221	21	-	-	JJ
cord-320092-0qnvydux	221	22	translational	translational	JJ
cord-320092-0qnvydux	221	23	modifications	modification	NNS
cord-320092-0qnvydux	221	24	.	.	.
cord-320092-0qnvydux	222	1	And	and	CC
cord-320092-0qnvydux	222	2	third	third	RB
cord-320092-0qnvydux	222	3	,	,	,
cord-320092-0qnvydux	222	4	the	the	DT
cord-320092-0qnvydux	222	5	potential	potential	JJ
cord-320092-0qnvydux	222	6	link	link	NN
cord-320092-0qnvydux	222	7	to	to	IN
cord-320092-0qnvydux	222	8	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	222	9	could	could	MD
cord-320092-0qnvydux	222	10	be	be	VB
cord-320092-0qnvydux	222	11	relied	rely	VBN
cord-320092-0qnvydux	222	12	upon	upon	IN
cord-320092-0qnvydux	222	13	in	in	IN
cord-320092-0qnvydux	222	14	cellbased	cellbased	JJ
cord-320092-0qnvydux	222	15	assays	assay	NNS
cord-320092-0qnvydux	222	16	to	to	TO
cord-320092-0qnvydux	222	17	determine	determine	VB
cord-320092-0qnvydux	222	18	the	the	DT
cord-320092-0qnvydux	222	19	possibility	possibility	NN
cord-320092-0qnvydux	222	20	of	of	IN
cord-320092-0qnvydux	222	21	the	the	DT
cord-320092-0qnvydux	222	22	involvement	involvement	NN
cord-320092-0qnvydux	222	23	of	of	IN
cord-320092-0qnvydux	222	24	the	the	DT
cord-320092-0qnvydux	222	25	spike	spike	NN
cord-320092-0qnvydux	222	26	protein	protein	NN
cord-320092-0qnvydux	222	27	in	in	IN
cord-320092-0qnvydux	222	28	iron	iron	NN
cord-320092-0qnvydux	222	29	biology	biology	NN
cord-320092-0qnvydux	222	30	.	.	.
cord-320092-0qnvydux	223	1	The	the	DT
cord-320092-0qnvydux	223	2	first	first	JJ
cord-320092-0qnvydux	223	3	draft	draft	NN
cord-320092-0qnvydux	223	4	of	of	IN
cord-320092-0qnvydux	223	5	this	this	DT
cord-320092-0qnvydux	223	6	manuscript	manuscript	NN
cord-320092-0qnvydux	223	7	was	be	VBD
cord-320092-0qnvydux	223	8	posted	post	VBN
cord-320092-0qnvydux	223	9	on	on	IN
cord-320092-0qnvydux	223	10	27	27	CD
cord-320092-0qnvydux	223	11	March	March	NNP
cord-320092-0qnvydux	223	12	2020	2020	CD
cord-320092-0qnvydux	223	13	on	on	IN
cord-320092-0qnvydux	223	14	the	the	DT
cord-320092-0qnvydux	223	15	arXiv	arxiv	NN
cord-320092-0qnvydux	223	16	preprint	preprint	NN
cord-320092-0qnvydux	223	17	server	server	NN
cord-320092-0qnvydux	223	18	(	(	-LRB-
cord-320092-0qnvydux	223	19	arxiv.org/abs/2003.12191v1	arxiv.org/abs/2003.12191v1	NN
cord-320092-0qnvydux	223	20	)	)	-RRB-
cord-320092-0qnvydux	223	21	.	.	.
cord-320092-0qnvydux	224	1	Thanks	thank	NNS
cord-320092-0qnvydux	224	2	are	be	VBP
cord-320092-0qnvydux	224	3	due	due	JJ
cord-320092-0qnvydux	224	4	to	to	IN
cord-320092-0qnvydux	224	5	Gerold	Gerold	NNP
cord-320092-0qnvydux	224	6	Schmitt	Schmitt	NNP
cord-320092-0qnvydux	224	7	-	-	HYPH
cord-320092-0qnvydux	224	8	Ulms	Ulms	NNP
cord-320092-0qnvydux	224	9	(	(	-LRB-
cord-320092-0qnvydux	224	10	University	University	NNP
cord-320092-0qnvydux	224	11	of	of	IN
cord-320092-0qnvydux	224	12	Toronto	Toronto	NNP
cord-320092-0qnvydux	224	13	)	)	-RRB-
cord-320092-0qnvydux	224	14	and	and	CC
cord-320092-0qnvydux	224	15	Farnaz	Farnaz	NNP
cord-320092-0qnvydux	224	16	Fahimi	Fahimi	NNP
cord-320092-0qnvydux	224	17	Hanzaee	Hanzaee	NNP
cord-320092-0qnvydux	224	18	(	(	-LRB-
cord-320092-0qnvydux	224	19	University	University	NNP
cord-320092-0qnvydux	224	20	College	College	NNP
cord-320092-0qnvydux	224	21	London	London	NNP
cord-320092-0qnvydux	224	22	)	)	-RRB-
cord-320092-0qnvydux	225	1	for	for	IN
cord-320092-0qnvydux	225	2	very	very	RB
cord-320092-0qnvydux	225	3	helpful	helpful	JJ
cord-320092-0qnvydux	225	4	discussions	discussion	NNS
cord-320092-0qnvydux	225	5	.	.	.
cord-320092-0qnvydux	226	1	Author	author	NN
cord-320092-0qnvydux	226	2	's	's	POS
cord-320092-0qnvydux	226	3	contributions	contribution	NNS
cord-320092-0qnvydux	227	1	S.E.	S.E.	NNP
cord-320092-0qnvydux	227	2	performed	perform	VBD
cord-320092-0qnvydux	227	3	the	the	DT
cord-320092-0qnvydux	227	4	analysis	analysis	NN
cord-320092-0qnvydux	227	5	and	and	CC
cord-320092-0qnvydux	227	6	wrote	write	VBD
cord-320092-0qnvydux	227	7	the	the	DT
cord-320092-0qnvydux	227	8	paper	paper	NN
cord-320092-0qnvydux	227	9	.	.	.
cord-320092-0qnvydux	228	1	The	the	DT
cord-320092-0qnvydux	228	2	author(s	author(s	NNP
cord-320092-0qnvydux	228	3	)	)	-RRB-
cord-320092-0qnvydux	228	4	read	read	VBD
cord-320092-0qnvydux	228	5	and	and	CC
cord-320092-0qnvydux	228	6	approved	approve	VBD
cord-320092-0qnvydux	228	7	the	the	DT
cord-320092-0qnvydux	228	8	final	final	JJ
cord-320092-0qnvydux	228	9	manuscript	manuscript	NN
cord-320092-0qnvydux	228	10	.	.	.
cord-320092-0qnvydux	229	1	Author	author	NN
cord-320092-0qnvydux	229	2	's	's	POS
cord-320092-0qnvydux	229	3	information	information	NN
cord-320092-0qnvydux	229	4	S.E.	S.E.	NNP
cord-320092-0qnvydux	229	5	holds	hold	VBZ
cord-320092-0qnvydux	229	6	a	a	DT
cord-320092-0qnvydux	229	7	Ph.D.	ph.d.	NN
cord-320092-0qnvydux	229	8	in	in	IN
cord-320092-0qnvydux	229	9	laboratory	laboratory	NN
cord-320092-0qnvydux	229	10	medicine	medicine	NN
cord-320092-0qnvydux	229	11	and	and	CC
cord-320092-0qnvydux	229	12	pathobiology	pathobiology	NN
cord-320092-0qnvydux	229	13	from	from	IN
cord-320092-0qnvydux	229	14	the	the	DT
cord-320092-0qnvydux	229	15	University	University	NNP
cord-320092-0qnvydux	229	16	of	of	IN
cord-320092-0qnvydux	229	17	Toronto	Toronto	NNP
cord-320092-0qnvydux	229	18	,	,	,
cord-320092-0qnvydux	229	19	and	and	CC
cord-320092-0qnvydux	229	20	was	be	VBD
cord-320092-0qnvydux	229	21	a	a	DT
cord-320092-0qnvydux	229	22	postdoctoral	postdoctoral	JJ
cord-320092-0qnvydux	229	23	fellow	fellow	NN
cord-320092-0qnvydux	229	24	at	at	IN
cord-320092-0qnvydux	229	25	the	the	DT
cord-320092-0qnvydux	229	26	Whitehead	Whitehead	NNP
cord-320092-0qnvydux	229	27	Institute	Institute	NNP
cord-320092-0qnvydux	229	28	for	for	IN
cord-320092-0qnvydux	229	29	Biomedical	Biomedical	NNP
cord-320092-0qnvydux	229	30	Research	Research	NNP
cord-320092-0qnvydux	229	31	and	and	CC
cord-320092-0qnvydux	229	32	the	the	DT
cord-320092-0qnvydux	229	33	Computer	Computer	NNP
cord-320092-0qnvydux	229	34	Science	Science	NNP
cord-320092-0qnvydux	229	35	and	and	CC
cord-320092-0qnvydux	229	36	Artificial	Artificial	NNP
cord-320092-0qnvydux	229	37	Intelligence	Intelligence	NNP
cord-320092-0qnvydux	229	38	Laboratory	Laboratory	NNP
cord-320092-0qnvydux	229	39	at	at	IN
cord-320092-0qnvydux	229	40	the	the	DT
cord-320092-0qnvydux	229	41	Massachusetts	Massachusetts	NNP
cord-320092-0qnvydux	229	42	Institute	Institute	NNP
cord-320092-0qnvydux	229	43	of	of	IN
cord-320092-0qnvydux	229	44	Technology	Technology	NNP
cord-320092-0qnvydux	229	45	.	.	.
cord-320092-0qnvydux	230	1	He	-PRON-	PRP
cord-320092-0qnvydux	230	2	is	be	VBZ
cord-320092-0qnvydux	230	3	currently	currently	RB
cord-320092-0qnvydux	230	4	a	a	DT
cord-320092-0qnvydux	230	5	Ph.D.	ph.d.	NN
cord-320092-0qnvydux	230	6	student	student	NN
cord-320092-0qnvydux	230	7	at	at	IN
cord-320092-0qnvydux	230	8	the	the	DT
cord-320092-0qnvydux	230	9	Department	Department	NNP
cord-320092-0qnvydux	230	10	of	of	IN
cord-320092-0qnvydux	230	11	Philosophy	Philosophy	NNP
cord-320092-0qnvydux	230	12	at	at	IN
cord-320092-0qnvydux	230	13	University	University	NNP
cord-320092-0qnvydux	230	14	College	College	NNP
cord-320092-0qnvydux	230	15	London	London	NNP
cord-320092-0qnvydux	230	16	.	.	.
cord-320092-0qnvydux	231	1	The	the	DT
cord-320092-0qnvydux	231	2	author	author	NN
cord-320092-0qnvydux	231	3	is	be	VBZ
cord-320092-0qnvydux	231	4	supported	support	VBN
cord-320092-0qnvydux	231	5	by	by	IN
cord-320092-0qnvydux	231	6	a	a	DT
cord-320092-0qnvydux	231	7	University	University	NNP
cord-320092-0qnvydux	231	8	College	College	NNP
cord-320092-0qnvydux	231	9	London	London	NNP
cord-320092-0qnvydux	231	10	Overseas	Overseas	NNP
cord-320092-0qnvydux	231	11	Research	Research	NNP
cord-320092-0qnvydux	231	12	Scholarship	Scholarship	NNP
cord-320092-0qnvydux	231	13	.	.	.
cord-320092-0qnvydux	232	1	Availability	availability	NN
cord-320092-0qnvydux	232	2	of	of	IN
cord-320092-0qnvydux	232	3	data	datum	NNS
cord-320092-0qnvydux	232	4	and	and	CC
cord-320092-0qnvydux	232	5	materials	material	NNS
cord-320092-0qnvydux	233	1	All	all	DT
cord-320092-0qnvydux	233	2	sequences	sequence	NNS
cord-320092-0qnvydux	233	3	utilized	utilize	VBN
cord-320092-0qnvydux	233	4	are	be	VBP
cord-320092-0qnvydux	233	5	from	from	IN
cord-320092-0qnvydux	233	6	publicly	publicly	RB
cord-320092-0qnvydux	233	7	available	available	JJ
cord-320092-0qnvydux	233	8	repositories	repository	NNS
cord-320092-0qnvydux	233	9	.	.	.
cord-320092-0qnvydux	234	1	Accession	accession	NN
cord-320092-0qnvydux	234	2	numbers	number	NNS
cord-320092-0qnvydux	234	3	are	be	VBP
cord-320092-0qnvydux	234	4	provided	provide	VBN
cord-320092-0qnvydux	234	5	in	in	IN
cord-320092-0qnvydux	234	6	the	the	DT
cord-320092-0qnvydux	234	7	relevant	relevant	JJ
cord-320092-0qnvydux	234	8	sections	section	NNS
cord-320092-0qnvydux	234	9	.	.	.
cord-320092-0qnvydux	235	1	Table	table	NN
cord-320092-0qnvydux	235	2	1	1	CD
cord-320092-0qnvydux	235	3	Points	point	NNS
cord-320092-0qnvydux	235	4	of	of	IN
cord-320092-0qnvydux	235	5	similarity	similarity	NN
cord-320092-0qnvydux	235	6	and	and	CC
cord-320092-0qnvydux	235	7	divergence	divergence	NN
cord-320092-0qnvydux	235	8	between	between	IN
cord-320092-0qnvydux	235	9	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	235	10	and	and	CC
cord-320092-0qnvydux	235	11	the	the	DT
cord-320092-0qnvydux	235	12	coronavirus	coronavirus	NN
cord-320092-0qnvydux	235	13	spike	spike	NN
cord-320092-0qnvydux	235	14	protein	protein	NN
cord-320092-0qnvydux	235	15	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	235	16	domain	domain	NN
cord-320092-0qnvydux	235	17	based	base	VBN
cord-320092-0qnvydux	235	18	on	on	IN
cord-320092-0qnvydux	235	19	current	current	JJ
cord-320092-0qnvydux	235	20	knowledge	knowledge	NN
cord-320092-0qnvydux	235	21	of	of	IN
cord-320092-0qnvydux	235	22	the	the	DT
cord-320092-0qnvydux	235	23	viral	viral	JJ
cord-320092-0qnvydux	235	24	protein	protein	NN
cord-320092-0qnvydux	235	25	and	and	CC
cord-320092-0qnvydux	235	26	its	-PRON-	PRP$
cord-320092-0qnvydux	235	27	pathobiology	pathobiology	NN
cord-320092-0qnvydux	235	28	(	(	-LRB-
cord-320092-0qnvydux	235	29	see	see	VB
cord-320092-0qnvydux	235	30	main	main	JJ
cord-320092-0qnvydux	235	31	text	text	NN
cord-320092-0qnvydux	235	32	for	for	IN
cord-320092-0qnvydux	235	33	references	reference	NNS
cord-320092-0qnvydux	235	34	)	)	-RRB-
cord-320092-0qnvydux	236	1	Potential	potential	JJ
cord-320092-0qnvydux	236	2	Similarities	similarity	NNS
cord-320092-0qnvydux	236	3	Potential	potential	JJ
cord-320092-0qnvydux	236	4	Differences	difference	NNS
cord-320092-0qnvydux	236	5	1	1	CD
cord-320092-0qnvydux	236	6	.	.	.
cord-320092-0qnvydux	237	1	Protein	protein	NN
cord-320092-0qnvydux	237	2	sequence	sequence	NN
cord-320092-0qnvydux	237	3	:	:	:
cord-320092-0qnvydux	237	4	A	a	DT
cord-320092-0qnvydux	237	5	unique	unique	JJ
cord-320092-0qnvydux	237	6	but	but	CC
cord-320092-0qnvydux	237	7	restricted	restricted	JJ
cord-320092-0qnvydux	237	8	sequence	sequence	NN
cord-320092-0qnvydux	237	9	similarity	similarity	NN
cord-320092-0qnvydux	237	10	exists	exist	VBZ
cord-320092-0qnvydux	237	11	between	between	IN
cord-320092-0qnvydux	237	12	mature	mature	JJ
cord-320092-0qnvydux	237	13	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	237	14	and	and	CC
cord-320092-0qnvydux	237	15	the	the	DT
cord-320092-0qnvydux	237	16	cysteine	cysteine	NN
cord-320092-0qnvydux	237	17	-	-	HYPH
cord-320092-0qnvydux	237	18	rich	rich	JJ
cord-320092-0qnvydux	237	19	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	237	20	tail	tail	NN
cord-320092-0qnvydux	237	21	of	of	IN
cord-320092-0qnvydux	237	22	coronavirus	coronavirus	NN
cord-320092-0qnvydux	237	23	spike	spike	NN
cord-320092-0qnvydux	237	24	proteins	protein	NNS
cord-320092-0qnvydux	237	25	.	.	.
cord-320092-0qnvydux	238	1	1	1	LS
cord-320092-0qnvydux	238	2	.	.	.
cord-320092-0qnvydux	239	1	Protein	protein	NN
cord-320092-0qnvydux	239	2	length	length	NN
cord-320092-0qnvydux	239	3	and	and	CC
cord-320092-0qnvydux	239	4	domains	domain	NNS
cord-320092-0qnvydux	240	1	:	:	:
cord-320092-0qnvydux	240	2	Coronavirus	Coronavirus	NNP
cord-320092-0qnvydux	240	3	spike	spike	NN
cord-320092-0qnvydux	240	4	proteins	protein	NNS
cord-320092-0qnvydux	240	5	are	be	VBP
cord-320092-0qnvydux	240	6	much	much	RB
cord-320092-0qnvydux	240	7	larger	large	JJR
cord-320092-0qnvydux	240	8	,	,	,
cord-320092-0qnvydux	240	9	multi	multi	JJ
cord-320092-0qnvydux	240	10	-	-	NN
cord-320092-0qnvydux	240	11	domain	domain	NN
cord-320092-0qnvydux	240	12	,	,	,
cord-320092-0qnvydux	240	13	proteins	protein	NNS
cord-320092-0qnvydux	240	14	compared	compare	VBN
cord-320092-0qnvydux	240	15	to	to	IN
cord-320092-0qnvydux	240	16	the	the	DT
cord-320092-0qnvydux	240	17	relatively	relatively	RB
cord-320092-0qnvydux	240	18	short	short	JJ
cord-320092-0qnvydux	240	19	-	-	HYPH
cord-320092-0qnvydux	240	20	length	length	NN
cord-320092-0qnvydux	240	21	hepcidin	hepcidin	NN
cord-320092-0qnvydux	240	22	proteins	protein	NNS
cord-320092-0qnvydux	240	23	.	.	.
cord-320092-0qnvydux	241	1	Post	post	JJ
cord-320092-0qnvydux	241	2	-	-	JJ
cord-320092-0qnvydux	241	3	translational	translational	JJ
cord-320092-0qnvydux	241	4	processing	processing	NN
cord-320092-0qnvydux	241	5	:	:	:
cord-320092-0qnvydux	242	1	The	the	DT
cord-320092-0qnvydux	242	2	proprotein	proprotein	NNP
cord-320092-0qnvydux	242	3	convertase	convertase	NN
cord-320092-0qnvydux	242	4	furin	furin	NN
cord-320092-0qnvydux	242	5	cleaves	cleave	VBZ
cord-320092-0qnvydux	242	6	prohepcidin	prohepcidin	NN
cord-320092-0qnvydux	242	7	,	,	,
cord-320092-0qnvydux	242	8	and	and	CC
cord-320092-0qnvydux	242	9	has	have	VBZ
cord-320092-0qnvydux	242	10	been	be	VBN
cord-320092-0qnvydux	242	11	reported	report	VBN
cord-320092-0qnvydux	242	12	to	to	TO
cord-320092-0qnvydux	242	13	also	also	RB
cord-320092-0qnvydux	242	14	activate	activate	VB
cord-320092-0qnvydux	242	15	(	(	-LRB-
cord-320092-0qnvydux	242	16	the	the	DT
cord-320092-0qnvydux	242	17	ectodomain	ectodomain	NN
cord-320092-0qnvydux	242	18	of	of	IN
cord-320092-0qnvydux	242	19	)	)	-RRB-
cord-320092-0qnvydux	242	20	the	the	DT
cord-320092-0qnvydux	242	21	SARS	SARS	NNP
cord-320092-0qnvydux	242	22	-	-	HYPH
cord-320092-0qnvydux	242	23	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	242	24	spike	spike	NN
cord-320092-0qnvydux	242	25	protein	protein	NN
cord-320092-0qnvydux	242	26	.	.	.
cord-320092-0qnvydux	243	1	2	2	LS
cord-320092-0qnvydux	243	2	.	.	.
cord-320092-0qnvydux	244	1	Post	post	JJ
cord-320092-0qnvydux	244	2	-	-	JJ
cord-320092-0qnvydux	244	3	translational	translational	JJ
cord-320092-0qnvydux	244	4	modification	modification	NN
cord-320092-0qnvydux	244	5	:	:	:
cord-320092-0qnvydux	244	6	Cysteines	cysteine	NNS
cord-320092-0qnvydux	244	7	in	in	IN
cord-320092-0qnvydux	244	8	the	the	DT
cord-320092-0qnvydux	244	9	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	244	10	tail	tail	NN
cord-320092-0qnvydux	244	11	of	of	IN
cord-320092-0qnvydux	244	12	coronavirus	coronavirus	NN
cord-320092-0qnvydux	244	13	spike	spike	NN
cord-320092-0qnvydux	244	14	proteins	protein	NNS
cord-320092-0qnvydux	244	15	are	be	VBP
cord-320092-0qnvydux	244	16	thought	think	VBN
cord-320092-0qnvydux	244	17	to	to	TO
cord-320092-0qnvydux	244	18	be	be	VB
cord-320092-0qnvydux	244	19	palmitoylation	palmitoylation	NNP
cord-320092-0qnvydux	244	20	acceptor	acceptor	NN
cord-320092-0qnvydux	244	21	residues	residue	NNS
cord-320092-0qnvydux	244	22	,	,	,
cord-320092-0qnvydux	244	23	and	and	CC
cord-320092-0qnvydux	244	24	this	this	DT
cord-320092-0qnvydux	244	25	modification	modification	NN
cord-320092-0qnvydux	244	26	has	have	VBZ
cord-320092-0qnvydux	244	27	thus	thus	RB
cord-320092-0qnvydux	244	28	far	far	RB
cord-320092-0qnvydux	244	29	not	not	RB
cord-320092-0qnvydux	244	30	been	be	VBN
cord-320092-0qnvydux	244	31	reported	report	VBN
cord-320092-0qnvydux	244	32	to	to	TO
cord-320092-0qnvydux	244	33	be	be	VB
cord-320092-0qnvydux	244	34	reversible	reversible	JJ
cord-320092-0qnvydux	244	35	.	.	.
cord-320092-0qnvydux	245	1	Cysteines	Cysteines	NNP
cord-320092-0qnvydux	245	2	in	in	IN
cord-320092-0qnvydux	245	3	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	245	4	are	be	VBP
cord-320092-0qnvydux	245	5	used	use	VBN
cord-320092-0qnvydux	245	6	to	to	TO
cord-320092-0qnvydux	245	7	form	form	VB
cord-320092-0qnvydux	245	8	disulfide	disulfide	JJ
cord-320092-0qnvydux	245	9	bonds	bond	NNS
cord-320092-0qnvydux	245	10	.	.	.
cord-320092-0qnvydux	246	1	3	3	LS
cord-320092-0qnvydux	246	2	.	.	.
cord-320092-0qnvydux	247	1	Cytokine	cytokine	NN
cord-320092-0qnvydux	247	2	storm	storm	NN
cord-320092-0qnvydux	247	3	:	:	:
cord-320092-0qnvydux	247	4	IL-6-mediated	il-6-mediate	VBN
cord-320092-0qnvydux	247	5	inflammatory	inflammatory	JJ
cord-320092-0qnvydux	247	6	responses	response	NNS
cord-320092-0qnvydux	247	7	have	have	VBP
cord-320092-0qnvydux	247	8	been	be	VBN
cord-320092-0qnvydux	247	9	reported	report	VBN
cord-320092-0qnvydux	247	10	in	in	IN
cord-320092-0qnvydux	247	11	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	247	12	patients	patient	NNS
cord-320092-0qnvydux	247	13	.	.	.
cord-320092-0qnvydux	248	1	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	248	2	production	production	NN
cord-320092-0qnvydux	248	3	in	in	IN
cord-320092-0qnvydux	248	4	the	the	DT
cord-320092-0qnvydux	248	5	liver	liver	NN
cord-320092-0qnvydux	248	6	is	be	VBZ
cord-320092-0qnvydux	248	7	induced	induce	VBN
cord-320092-0qnvydux	248	8	by	by	IN
cord-320092-0qnvydux	248	9	IL-6	IL-6	NNP
cord-320092-0qnvydux	248	10	and	and	CC
cord-320092-0qnvydux	248	11	is	be	VBZ
cord-320092-0qnvydux	248	12	well	well	RB
cord-320092-0qnvydux	248	13	-	-	HYPH
cord-320092-0qnvydux	248	14	studied	study	VBN
cord-320092-0qnvydux	248	15	in	in	IN
cord-320092-0qnvydux	248	16	the	the	DT
cord-320092-0qnvydux	248	17	context	context	NN
cord-320092-0qnvydux	248	18	of	of	IN
cord-320092-0qnvydux	248	19	the	the	DT
cord-320092-0qnvydux	248	20	anemia	anemia	NN
cord-320092-0qnvydux	248	21	of	of	IN
cord-320092-0qnvydux	248	22	inflammation	inflammation	NN
cord-320092-0qnvydux	248	23	.	.	.
cord-320092-0qnvydux	249	1	In	in	IN
cord-320092-0qnvydux	249	2	addition	addition	NN
cord-320092-0qnvydux	249	3	,	,	,
cord-320092-0qnvydux	249	4	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	249	5	may	may	MD
cord-320092-0qnvydux	249	6	be	be	VB
cord-320092-0qnvydux	249	7	associated	associate	VBN
cord-320092-0qnvydux	249	8	with	with	IN
cord-320092-0qnvydux	249	9	a	a	DT
cord-320092-0qnvydux	249	10	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	249	11	-	-	HYPH
cord-320092-0qnvydux	249	12	disease	disease	NN
cord-320092-0qnvydux	249	13	-	-	HYPH
cord-320092-0qnvydux	249	14	like	like	JJ
cord-320092-0qnvydux	249	15	systemic	systemic	JJ
cord-320092-0qnvydux	249	16	vasculitis	vasculitis	JJ
cord-320092-0qnvydux	249	17	manifestation	manifestation	NN
cord-320092-0qnvydux	249	18	in	in	IN
cord-320092-0qnvydux	249	19	children	child	NNS
cord-320092-0qnvydux	249	20	,	,	,
cord-320092-0qnvydux	249	21	and	and	CC
cord-320092-0qnvydux	249	22	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	249	23	levels	level	NNS
cord-320092-0qnvydux	249	24	have	have	VBP
cord-320092-0qnvydux	249	25	also	also	RB
cord-320092-0qnvydux	249	26	been	be	VBN
cord-320092-0qnvydux	249	27	suggested	suggest	VBN
cord-320092-0qnvydux	249	28	as	as	IN
cord-320092-0qnvydux	249	29	a	a	DT
cord-320092-0qnvydux	249	30	biomarker	biomarker	NN
cord-320092-0qnvydux	249	31	for	for	IN
cord-320092-0qnvydux	249	32	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	249	33	disease	disease	NN
cord-320092-0qnvydux	249	34	.	.	.
cord-320092-0qnvydux	250	1	3	3	LS
cord-320092-0qnvydux	250	2	.	.	.
cord-320092-0qnvydux	251	1	Localization	localization	NN
cord-320092-0qnvydux	251	2	:	:	:
cord-320092-0qnvydux	252	1	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	252	2	is	be	VBZ
cord-320092-0qnvydux	252	3	thought	think	VBN
cord-320092-0qnvydux	252	4	to	to	TO
cord-320092-0qnvydux	252	5	interact	interact	VB
cord-320092-0qnvydux	252	6	with	with	IN
cord-320092-0qnvydux	252	7	its	-PRON-	PRP$
cord-320092-0qnvydux	252	8	main	main	JJ
cord-320092-0qnvydux	252	9	(	(	-LRB-
cord-320092-0qnvydux	252	10	iron	iron	NN
cord-320092-0qnvydux	252	11	-	-	HYPH
cord-320092-0qnvydux	252	12	bound	bind	VBN
cord-320092-0qnvydux	252	13	)	)	-RRB-
cord-320092-0qnvydux	252	14	interactor	interactor	NNP
cord-320092-0qnvydux	252	15	,	,	,
cord-320092-0qnvydux	252	16	ferroportin	ferroportin	NNP
cord-320092-0qnvydux	252	17	,	,	,
cord-320092-0qnvydux	252	18	extracellularly	extracellularly	RB
cord-320092-0qnvydux	252	19	,	,	,
cord-320092-0qnvydux	252	20	whereas	whereas	IN
cord-320092-0qnvydux	252	21	the	the	DT
cord-320092-0qnvydux	252	22	spike	spike	NN
cord-320092-0qnvydux	252	23	protein	protein	NN
cord-320092-0qnvydux	252	24	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	252	25	tail	tail	NN
cord-320092-0qnvydux	252	26	does	do	VBZ
cord-320092-0qnvydux	252	27	not	not	RB
cord-320092-0qnvydux	252	28	face	face	VB
cord-320092-0qnvydux	252	29	the	the	DT
cord-320092-0qnvydux	252	30	environment	environment	NN
cord-320092-0qnvydux	252	31	outside	outside	IN
cord-320092-0qnvydux	252	32	the	the	DT
cord-320092-0qnvydux	252	33	viral	viral	JJ
cord-320092-0qnvydux	252	34	membrane	membrane	NN
cord-320092-0qnvydux	252	35	.	.	.
cord-320092-0qnvydux	253	1	(	(	-LRB-
cord-320092-0qnvydux	253	2	However	however	RB
cord-320092-0qnvydux	253	3	,	,	,
cord-320092-0qnvydux	253	4	the	the	DT
cord-320092-0qnvydux	253	5	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	253	6	tail	tail	NN
cord-320092-0qnvydux	253	7	associates	associate	NNS
cord-320092-0qnvydux	253	8	with	with	IN
cord-320092-0qnvydux	253	9	the	the	DT
cord-320092-0qnvydux	253	10	plasma	plasma	NN
cord-320092-0qnvydux	253	11	membrane	membrane	NN
cord-320092-0qnvydux	253	12	itself	-PRON-	PRP
cord-320092-0qnvydux	253	13	aided	aid	VBN
cord-320092-0qnvydux	253	14	by	by	IN
cord-320092-0qnvydux	253	15	its	-PRON-	PRP$
cord-320092-0qnvydux	253	16	palmitoylation	palmitoylation	NN
cord-320092-0qnvydux	253	17	modifications	modification	NNS
cord-320092-0qnvydux	253	18	,	,	,
cord-320092-0qnvydux	253	19	and	and	CC
cord-320092-0qnvydux	253	20	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	253	21	may	may	MD
cord-320092-0qnvydux	253	22	interact	interact	VB
cord-320092-0qnvydux	253	23	with	with	IN
cord-320092-0qnvydux	253	24	ferroportin	ferroportin	NNP
cord-320092-0qnvydux	253	25	close	close	RB
cord-320092-0qnvydux	253	26	to	to	IN
cord-320092-0qnvydux	253	27	ferroportin	ferroportin	NNP
cord-320092-0qnvydux	253	28	's	's	POS
cord-320092-0qnvydux	253	29	transmembrane	transmembrane	NN
cord-320092-0qnvydux	253	30	regions	region	NNS
cord-320092-0qnvydux	253	31	in	in	IN
cord-320092-0qnvydux	253	32	addition	addition	NN
cord-320092-0qnvydux	253	33	to	to	IN
cord-320092-0qnvydux	253	34	extracellular	extracellular	JJ
cord-320092-0qnvydux	253	35	residues	residue	NNS
cord-320092-0qnvydux	253	36	.	.	.
cord-320092-0qnvydux	253	37	)	)	-RRB-
cord-320092-0qnvydux	254	1	4	4	LS
cord-320092-0qnvydux	254	2	.	.	.
cord-320092-0qnvydux	255	1	Hypoxia	hypoxia	NN
cord-320092-0qnvydux	255	2	/	/	SYM
cord-320092-0qnvydux	255	3	Hypoxemia	Hypoxemia	NNP
cord-320092-0qnvydux	255	4	:	:	:
cord-320092-0qnvydux	255	5	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	255	6	may	may	MD
cord-320092-0qnvydux	255	7	lead	lead	VB
cord-320092-0qnvydux	255	8	to	to	IN
cord-320092-0qnvydux	255	9	symptoms	symptom	NNS
cord-320092-0qnvydux	255	10	resembling	resemble	VBG
cord-320092-0qnvydux	255	11	,	,	,
cord-320092-0qnvydux	255	12	but	but	CC
cord-320092-0qnvydux	255	13	differentiable	differentiable	JJ
cord-320092-0qnvydux	255	14	from	from	IN
cord-320092-0qnvydux	255	15	,	,	,
cord-320092-0qnvydux	255	16	altitude	altitude	NN
cord-320092-0qnvydux	255	17	illness	illness	NN
cord-320092-0qnvydux	255	18	,	,	,
cord-320092-0qnvydux	255	19	and	and	CC
cord-320092-0qnvydux	255	20	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	255	21	expression	expression	NN
cord-320092-0qnvydux	255	22	levels	level	NNS
cord-320092-0qnvydux	255	23	have	have	VBP
cord-320092-0qnvydux	255	24	also	also	RB
cord-320092-0qnvydux	255	25	been	be	VBN
cord-320092-0qnvydux	255	26	studied	study	VBN
cord-320092-0qnvydux	255	27	in	in	IN
cord-320092-0qnvydux	255	28	the	the	DT
cord-320092-0qnvydux	255	29	context	context	NN
cord-320092-0qnvydux	255	30	of	of	IN
cord-320092-0qnvydux	255	31	high	high	JJ
cord-320092-0qnvydux	255	32	-	-	HYPH
cord-320092-0qnvydux	255	33	altitude	altitude	NN
cord-320092-0qnvydux	255	34	acclimatization	acclimatization	NN
cord-320092-0qnvydux	255	35	.	.	.
cord-320092-0qnvydux	256	1	Reply	reply	NN
cord-320092-0qnvydux	256	2	:	:	:
cord-320092-0qnvydux	257	1	iron	iron	NN
cord-320092-0qnvydux	257	2	chelation	chelation	NN
cord-320092-0qnvydux	257	3	may	may	MD
cord-320092-0qnvydux	257	4	harm	harm	VB
cord-320092-0qnvydux	257	5	patients	patient	NNS
cord-320092-0qnvydux	257	6	with	with	IN
cord-320092-0qnvydux	257	7	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	257	8	A	a	DT
cord-320092-0qnvydux	257	9	new	new	JJ
cord-320092-0qnvydux	257	10	multigene	multigene	JJ
cord-320092-0qnvydux	257	11	family	family	NN
cord-320092-0qnvydux	257	12	inducible	inducible	JJ
cord-320092-0qnvydux	257	13	by	by	IN
cord-320092-0qnvydux	257	14	tobacco	tobacco	NN
cord-320092-0qnvydux	257	15	mosaic	mosaic	NN
cord-320092-0qnvydux	257	16	virus	virus	NN
cord-320092-0qnvydux	257	17	or	or	CC
cord-320092-0qnvydux	257	18	salicylic	salicylic	JJ
cord-320092-0qnvydux	257	19	acid	acid	NN
cord-320092-0qnvydux	257	20	in	in	IN
cord-320092-0qnvydux	257	21	tobacco	tobacco	NN
cord-320092-0qnvydux	257	22	Critical	critical	JJ
cord-320092-0qnvydux	257	23	role	role	NN
cord-320092-0qnvydux	257	24	for	for	IN
cord-320092-0qnvydux	257	25	iron	iron	NN
cord-320092-0qnvydux	257	26	accumulation	accumulation	NN
cord-320092-0qnvydux	257	27	in	in	IN
cord-320092-0qnvydux	257	28	the	the	DT
cord-320092-0qnvydux	257	29	pathogenesis	pathogenesis	NN
cord-320092-0qnvydux	257	30	of	of	IN
cord-320092-0qnvydux	257	31	fibrotic	fibrotic	JJ
cord-320092-0qnvydux	257	32	lung	lung	NN
cord-320092-0qnvydux	257	33	disease	disease	NN
cord-320092-0qnvydux	257	34	SARS	SARS	NNP
cord-320092-0qnvydux	257	35	-	-	HYPH
cord-320092-0qnvydux	257	36	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	257	37	strategically	strategically	RB
cord-320092-0qnvydux	257	38	mimics	mimic	VBZ
cord-320092-0qnvydux	257	39	proteolytic	proteolytic	JJ
cord-320092-0qnvydux	257	40	activation	activation	NN
cord-320092-0qnvydux	257	41	of	of	IN
cord-320092-0qnvydux	257	42	human	human	JJ
cord-320092-0qnvydux	257	43	ENaC	ENaC	NNP
cord-320092-0qnvydux	258	1	The	the	DT
cord-320092-0qnvydux	258	2	proximal	proximal	JJ
cord-320092-0qnvydux	258	3	origin	origin	NN
cord-320092-0qnvydux	258	4	of	of	IN
cord-320092-0qnvydux	258	5	SARS	SARS	NNP
cord-320092-0qnvydux	258	6	-	-	HYPH
cord-320092-0qnvydux	258	7	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	259	1	Forging	forge	VBG
cord-320092-0qnvydux	259	2	a	a	DT
cord-320092-0qnvydux	259	3	field	field	NN
cord-320092-0qnvydux	259	4	:	:	:
cord-320092-0qnvydux	259	5	the	the	DT
cord-320092-0qnvydux	259	6	golden	golden	JJ
cord-320092-0qnvydux	259	7	age	age	NN
cord-320092-0qnvydux	259	8	of	of	IN
cord-320092-0qnvydux	259	9	iron	iron	NN
cord-320092-0qnvydux	259	10	biology	biology	NN
cord-320092-0qnvydux	259	11	Differentiating	differentiate	VBG
cord-320092-0qnvydux	259	12	COVID-19	covid-19	JJ
cord-320092-0qnvydux	259	13	pneumonia	pneumonia	NN
cord-320092-0qnvydux	259	14	from	from	IN
cord-320092-0qnvydux	259	15	acute	acute	JJ
cord-320092-0qnvydux	259	16	respiratory	respiratory	JJ
cord-320092-0qnvydux	259	17	distress	distress	NN
cord-320092-0qnvydux	259	18	syndrome	syndrome	NN
cord-320092-0qnvydux	259	19	and	and	CC
cord-320092-0qnvydux	259	20	high	high	JJ
cord-320092-0qnvydux	259	21	altitude	altitude	NN
cord-320092-0qnvydux	259	22	pulmonary	pulmonary	JJ
cord-320092-0qnvydux	259	23	edema	edema	NN
cord-320092-0qnvydux	259	24	:	:	:
cord-320092-0qnvydux	259	25	therapeutic	therapeutic	JJ
cord-320092-0qnvydux	259	26	implications	implication	NNS
cord-320092-0qnvydux	260	1	Does	do	VBZ
cord-320092-0qnvydux	260	2	the	the	DT
cord-320092-0qnvydux	260	3	pathogenesis	pathogenesis	NN
cord-320092-0qnvydux	260	4	of	of	IN
cord-320092-0qnvydux	260	5	SARS	SARS	NNP
cord-320092-0qnvydux	260	6	-	-	HYPH
cord-320092-0qnvydux	260	7	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	260	8	virus	virus	NN
cord-320092-0qnvydux	260	9	decrease	decrease	NN
cord-320092-0qnvydux	260	10	at	at	IN
cord-320092-0qnvydux	260	11	high	high	JJ
cord-320092-0qnvydux	260	12	-	-	HYPH
cord-320092-0qnvydux	260	13	altitude	altitude	NN
cord-320092-0qnvydux	260	14	?	?	.
cord-320092-0qnvydux	261	1	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	261	2	regulation	regulation	NN
cord-320092-0qnvydux	261	3	by	by	IN
cord-320092-0qnvydux	261	4	innate	innate	JJ
cord-320092-0qnvydux	261	5	immune	immune	JJ
cord-320092-0qnvydux	261	6	and	and	CC
cord-320092-0qnvydux	261	7	infectious	infectious	JJ
cord-320092-0qnvydux	261	8	stimuli	stimulus	NNS
cord-320092-0qnvydux	262	1	Distinct	distinct	JJ
cord-320092-0qnvydux	262	2	patterns	pattern	NNS
cord-320092-0qnvydux	262	3	of	of	IN
cord-320092-0qnvydux	262	4	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	262	5	and	and	CC
cord-320092-0qnvydux	262	6	iron	iron	NN
cord-320092-0qnvydux	262	7	regulation	regulation	NN
cord-320092-0qnvydux	262	8	during	during	IN
cord-320092-0qnvydux	262	9	HIV-1	HIV-1	NNP
cord-320092-0qnvydux	262	10	,	,	,
cord-320092-0qnvydux	262	11	HBV	HBV	NNP
cord-320092-0qnvydux	262	12	,	,	,
cord-320092-0qnvydux	262	13	and	and	CC
cord-320092-0qnvydux	262	14	HCV	HCV	NNP
cord-320092-0qnvydux	262	15	infections	infection	NNS
cord-320092-0qnvydux	262	16	Structure	structure	NN
cord-320092-0qnvydux	262	17	-	-	HYPH
cord-320092-0qnvydux	262	18	function	function	NN
cord-320092-0qnvydux	262	19	analysis	analysis	NN
cord-320092-0qnvydux	262	20	of	of	IN
cord-320092-0qnvydux	262	21	ferroportin	ferroportin	NNP
cord-320092-0qnvydux	262	22	defines	define	VBZ
cord-320092-0qnvydux	262	23	the	the	DT
cord-320092-0qnvydux	262	24	binding	binding	NN
cord-320092-0qnvydux	262	25	site	site	NN
cord-320092-0qnvydux	262	26	and	and	CC
cord-320092-0qnvydux	262	27	an	an	DT
cord-320092-0qnvydux	262	28	alternative	alternative	JJ
cord-320092-0qnvydux	262	29	mechanism	mechanism	NN
cord-320092-0qnvydux	262	30	of	of	IN
cord-320092-0qnvydux	262	31	action	action	NN
cord-320092-0qnvydux	262	32	of	of	IN
cord-320092-0qnvydux	262	33	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	262	34	SARS	SARS	NNP
cord-320092-0qnvydux	262	35	-	-	HYPH
cord-320092-0qnvydux	262	36	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	262	37	(	(	-LRB-
cord-320092-0qnvydux	262	38	COVID-19	covid-19	VB
cord-320092-0qnvydux	262	39	)	)	-RRB-
cord-320092-0qnvydux	262	40	by	by	IN
cord-320092-0qnvydux	262	41	the	the	DT
cord-320092-0qnvydux	262	42	numbers	number	NNS
cord-320092-0qnvydux	262	43	Patient	Patient	NNP
cord-320092-0qnvydux	262	44	blood	blood	NN
cord-320092-0qnvydux	262	45	management	management	NN
cord-320092-0qnvydux	262	46	during	during	IN
cord-320092-0qnvydux	262	47	the	the	DT
cord-320092-0qnvydux	262	48	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	262	49	pandemic	pandemic	NN
cord-320092-0qnvydux	262	50	:	:	:
cord-320092-0qnvydux	262	51	a	a	DT
cord-320092-0qnvydux	262	52	narrative	narrative	NN
cord-320092-0qnvydux	262	53	review	review	NN
cord-320092-0qnvydux	263	1	There	there	EX
cord-320092-0qnvydux	263	2	is	be	VBZ
cord-320092-0qnvydux	263	3	no	no	DT
cord-320092-0qnvydux	263	4	relationship	relationship	NN
cord-320092-0qnvydux	263	5	between	between	IN
cord-320092-0qnvydux	263	6	covid-19	covid-19	NN
cord-320092-0qnvydux	263	7	and	and	CC
cord-320092-0qnvydux	263	8	altitude	altitude	NN
cord-320092-0qnvydux	263	9	illness	illness	NN
cord-320092-0qnvydux	263	10	Discovery	Discovery	NNP
cord-320092-0qnvydux	263	11	and	and	CC
cord-320092-0qnvydux	263	12	development	development	NN
cord-320092-0qnvydux	263	13	of	of	IN
cord-320092-0qnvydux	263	14	TMPRSS6	TMPRSS6	NNP
cord-320092-0qnvydux	263	15	inhibitors	inhibitor	NNS
cord-320092-0qnvydux	263	16	modulating	modulate	VBG
cord-320092-0qnvydux	263	17	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	263	18	levels	level	NNS
cord-320092-0qnvydux	263	19	in	in	IN
cord-320092-0qnvydux	263	20	human	human	JJ
cord-320092-0qnvydux	263	21	hepatocytes	hepatocyte	NNS
cord-320092-0qnvydux	263	22	Architecture	Architecture	NNP
cord-320092-0qnvydux	263	23	of	of	IN
cord-320092-0qnvydux	263	24	the	the	DT
cord-320092-0qnvydux	263	25	SARS	SARS	NNP
cord-320092-0qnvydux	263	26	coronavirus	coronavirus	NN
cord-320092-0qnvydux	263	27	prefusion	prefusion	NN
cord-320092-0qnvydux	263	28	spike	spike	NN
cord-320092-0qnvydux	263	29	Structure	Structure	NNP
cord-320092-0qnvydux	263	30	of	of	IN
cord-320092-0qnvydux	263	31	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	263	32	-	-	HYPH
cord-320092-0qnvydux	263	33	bound	bind	VBN
cord-320092-0qnvydux	263	34	ferroportin	ferroportin	NNP
cord-320092-0qnvydux	263	35	reveals	reveal	VBZ
cord-320092-0qnvydux	263	36	iron	iron	NN
cord-320092-0qnvydux	263	37	homeostatic	homeostatic	JJ
cord-320092-0qnvydux	263	38	mechanisms	mechanism	NNS
cord-320092-0qnvydux	263	39	Imbalanced	imbalanced	JJ
cord-320092-0qnvydux	263	40	host	host	NN
cord-320092-0qnvydux	263	41	response	response	NN
cord-320092-0qnvydux	263	42	to	to	IN
cord-320092-0qnvydux	263	43	SARS	SARS	NNP
cord-320092-0qnvydux	263	44	-	-	HYPH
cord-320092-0qnvydux	263	45	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	263	46	drives	drive	VBZ
cord-320092-0qnvydux	263	47	development	development	NN
cord-320092-0qnvydux	263	48	of	of	IN
cord-320092-0qnvydux	263	49	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	264	1	The	the	DT
cord-320092-0qnvydux	264	2	coronavirus	coronavirus	NN
cord-320092-0qnvydux	264	3	spike	spike	NN
cord-320092-0qnvydux	264	4	protein	protein	NN
cord-320092-0qnvydux	264	5	is	be	VBZ
cord-320092-0qnvydux	264	6	a	a	DT
cord-320092-0qnvydux	264	7	class	class	NN
cord-320092-0qnvydux	264	8	I	-PRON-	PRP
cord-320092-0qnvydux	264	9	virus	virus	NN
cord-320092-0qnvydux	264	10	fusion	fusion	NN
cord-320092-0qnvydux	264	11	protein	protein	NN
cord-320092-0qnvydux	264	12	:	:	:
cord-320092-0qnvydux	264	13	structural	structural	JJ
cord-320092-0qnvydux	264	14	and	and	CC
cord-320092-0qnvydux	264	15	functional	functional	JJ
cord-320092-0qnvydux	264	16	characterization	characterization	NN
cord-320092-0qnvydux	264	17	of	of	IN
cord-320092-0qnvydux	264	18	the	the	DT
cord-320092-0qnvydux	264	19	fusion	fusion	NN
cord-320092-0qnvydux	264	20	core	core	NN
cord-320092-0qnvydux	264	21	complex	complex	JJ
cord-320092-0qnvydux	264	22	Iron	iron	NN
cord-320092-0qnvydux	264	23	-	-	HYPH
cord-320092-0qnvydux	264	24	deficiency	deficiency	NN
cord-320092-0qnvydux	264	25	anemia	anemia	NN
cord-320092-0qnvydux	264	26	U.	U.	NNP
cord-320092-0qnvydux	264	27	Coronavirus	Coronavirus	NNP
cord-320092-0qnvydux	265	1	COVID-19	covid-19	JJ
cord-320092-0qnvydux	265	2	global	global	JJ
cord-320092-0qnvydux	265	3	cases	case	NNS
cord-320092-0qnvydux	266	1	Coronavirus	Coronavirus	NNP
cord-320092-0qnvydux	266	2	-	-	HYPH
cord-320092-0qnvydux	266	3	induced	induce	VBN
cord-320092-0qnvydux	266	4	membrane	membrane	NN
cord-320092-0qnvydux	266	5	fusion	fusion	NN
cord-320092-0qnvydux	266	6	requires	require	VBZ
cord-320092-0qnvydux	266	7	the	the	DT
cord-320092-0qnvydux	266	8	cysteine	cysteine	JJ
cord-320092-0qnvydux	266	9	-	-	HYPH
cord-320092-0qnvydux	266	10	rich	rich	JJ
cord-320092-0qnvydux	266	11	domain	domain	NN
cord-320092-0qnvydux	266	12	in	in	IN
cord-320092-0qnvydux	266	13	the	the	DT
cord-320092-0qnvydux	266	14	spike	spike	NN
cord-320092-0qnvydux	266	15	protein	protein	NN
cord-320092-0qnvydux	266	16	COVID-19	covid-19	CD
cord-320092-0qnvydux	266	17	infection	infection	NN
cord-320092-0qnvydux	266	18	:	:	:
cord-320092-0qnvydux	266	19	the	the	DT
cord-320092-0qnvydux	266	20	China	China	NNP
cord-320092-0qnvydux	266	21	and	and	CC
cord-320092-0qnvydux	266	22	Italy	Italy	NNP
cord-320092-0qnvydux	266	23	perspectives	perspective	VBZ
cord-320092-0qnvydux	266	24	Epidemiological	epidemiological	JJ
cord-320092-0qnvydux	266	25	and	and	CC
cord-320092-0qnvydux	266	26	clinical	clinical	JJ
cord-320092-0qnvydux	266	27	characteristics	characteristic	NNS
cord-320092-0qnvydux	266	28	of	of	IN
cord-320092-0qnvydux	266	29	99	99	CD
cord-320092-0qnvydux	266	30	cases	case	NNS
cord-320092-0qnvydux	266	31	of	of	IN
cord-320092-0qnvydux	266	32	2019	2019	CD
cord-320092-0qnvydux	266	33	novel	novel	JJ
cord-320092-0qnvydux	266	34	coronavirus	coronavirus	NN
cord-320092-0qnvydux	266	35	pneumonia	pneumonia	NN
cord-320092-0qnvydux	266	36	in	in	IN
cord-320092-0qnvydux	266	37	Wuhan	Wuhan	NNP
cord-320092-0qnvydux	266	38	,	,	,
cord-320092-0qnvydux	266	39	China	China	NNP
cord-320092-0qnvydux	266	40	:	:	:
cord-320092-0qnvydux	267	1	a	a	DT
cord-320092-0qnvydux	267	2	descriptive	descriptive	JJ
cord-320092-0qnvydux	267	3	study	study	NN
cord-320092-0qnvydux	267	4	Is	be	VBZ
cord-320092-0qnvydux	267	5	the	the	DT
cord-320092-0qnvydux	267	6	prevalence	prevalence	NN
cord-320092-0qnvydux	267	7	of	of	IN
cord-320092-0qnvydux	267	8	anemia	anemia	NN
cord-320092-0qnvydux	267	9	in	in	IN
cord-320092-0qnvydux	267	10	children	child	NNS
cord-320092-0qnvydux	267	11	living	live	VBG
cord-320092-0qnvydux	267	12	at	at	IN
cord-320092-0qnvydux	267	13	high	high	JJ
cord-320092-0qnvydux	267	14	altitudes	altitude	NNS
cord-320092-0qnvydux	267	15	real	real	JJ
cord-320092-0qnvydux	267	16	?	?	.
cord-320092-0qnvydux	268	1	An	an	DT
cord-320092-0qnvydux	268	2	observational	observational	JJ
cord-320092-0qnvydux	268	3	study	study	NN
cord-320092-0qnvydux	268	4	in	in	IN
cord-320092-0qnvydux	268	5	Peru	Peru	NNP
cord-320092-0qnvydux	269	1	The	the	DT
cord-320092-0qnvydux	269	2	spike	spike	NN
cord-320092-0qnvydux	269	3	glycoprotein	glycoprotein	NN
cord-320092-0qnvydux	269	4	of	of	IN
cord-320092-0qnvydux	269	5	the	the	DT
cord-320092-0qnvydux	269	6	new	new	JJ
cord-320092-0qnvydux	269	7	coronavirus	coronavirus	NN
cord-320092-0qnvydux	269	8	2019-nCoV	2019-ncov	CD
cord-320092-0qnvydux	269	9	contains	contain	VBZ
cord-320092-0qnvydux	269	10	a	a	DT
cord-320092-0qnvydux	269	11	furin	furin	NN
cord-320092-0qnvydux	269	12	-	-	HYPH
cord-320092-0qnvydux	269	13	like	like	JJ
cord-320092-0qnvydux	269	14	cleavage	cleavage	NN
cord-320092-0qnvydux	269	15	site	site	NN
cord-320092-0qnvydux	269	16	absent	absent	JJ
cord-320092-0qnvydux	269	17	in	in	IN
cord-320092-0qnvydux	269	18	CoV	cov	NN
cord-320092-0qnvydux	269	19	of	of	IN
cord-320092-0qnvydux	269	20	the	the	DT
cord-320092-0qnvydux	269	21	same	same	JJ
cord-320092-0qnvydux	269	22	clade	clade	NN
cord-320092-0qnvydux	269	23	Targeting	target	VBG
cord-320092-0qnvydux	269	24	iron	iron	NN
cord-320092-0qnvydux	269	25	metabolism	metabolism	NN
cord-320092-0qnvydux	269	26	in	in	IN
cord-320092-0qnvydux	269	27	drug	drug	NN
cord-320092-0qnvydux	269	28	discovery	discovery	NN
cord-320092-0qnvydux	269	29	and	and	CC
cord-320092-0qnvydux	269	30	delivery	delivery	NN
cord-320092-0qnvydux	269	31	Regulation	Regulation	NNP
cord-320092-0qnvydux	269	32	of	of	IN
cord-320092-0qnvydux	269	33	iron	iron	NN
cord-320092-0qnvydux	269	34	acquisition	acquisition	NN
cord-320092-0qnvydux	269	35	and	and	CC
cord-320092-0qnvydux	269	36	storage	storage	NN
cord-320092-0qnvydux	269	37	:	:	:
cord-320092-0qnvydux	269	38	consequences	consequence	NNS
cord-320092-0qnvydux	269	39	for	for	IN
cord-320092-0qnvydux	269	40	iron	iron	NN
cord-320092-0qnvydux	269	41	-	-	HYPH
cord-320092-0qnvydux	269	42	linked	link	VBN
cord-320092-0qnvydux	269	43	disorders	disorder	NNS
cord-320092-0qnvydux	270	1	The	the	DT
cord-320092-0qnvydux	270	2	pathophysiology	pathophysiology	NN
cord-320092-0qnvydux	270	3	of	of	IN
cord-320092-0qnvydux	270	4	'	'	``
cord-320092-0qnvydux	270	5	happy	happy	JJ
cord-320092-0qnvydux	270	6	'	'	''
cord-320092-0qnvydux	270	7	hypoxemia	hypoxemia	NN
cord-320092-0qnvydux	270	8	in	in	IN
cord-320092-0qnvydux	270	9	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	270	10	The	the	DT
cord-320092-0qnvydux	270	11	discovery	discovery	NN
cord-320092-0qnvydux	270	12	of	of	IN
cord-320092-0qnvydux	270	13	a	a	DT
cord-320092-0qnvydux	270	14	putative	putative	JJ
cord-320092-0qnvydux	270	15	allosteric	allosteric	JJ
cord-320092-0qnvydux	270	16	site	site	NN
cord-320092-0qnvydux	270	17	in	in	IN
cord-320092-0qnvydux	270	18	the	the	DT
cord-320092-0qnvydux	270	19	SARS	SARS	NNP
cord-320092-0qnvydux	270	20	-	-	HYPH
cord-320092-0qnvydux	270	21	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	270	22	spike	spike	NN
cord-320092-0qnvydux	270	23	protein	protein	NN
cord-320092-0qnvydux	270	24	using	use	VBG
cord-320092-0qnvydux	270	25	an	an	DT
cord-320092-0qnvydux	270	26	integrated	integrate	VBN
cord-320092-0qnvydux	270	27	structural	structural	JJ
cord-320092-0qnvydux	270	28	/	/	SYM
cord-320092-0qnvydux	270	29	dynamic	dynamic	JJ
cord-320092-0qnvydux	270	30	approach	approach	NN
cord-320092-0qnvydux	271	1	An	an	DT
cord-320092-0qnvydux	271	2	interactive	interactive	JJ
cord-320092-0qnvydux	271	3	web	web	NN
cord-320092-0qnvydux	271	4	-	-	HYPH
cord-320092-0qnvydux	271	5	based	base	VBN
cord-320092-0qnvydux	271	6	dashboard	dashboard	NN
cord-320092-0qnvydux	271	7	to	to	TO
cord-320092-0qnvydux	271	8	track	track	VB
cord-320092-0qnvydux	271	9	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	271	10	in	in	IN
cord-320092-0qnvydux	271	11	real	real	JJ
cord-320092-0qnvydux	271	12	time	time	NN
cord-320092-0qnvydux	272	1	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	272	2	and	and	CC
cord-320092-0qnvydux	272	3	the	the	DT
cord-320092-0qnvydux	272	4	iron	iron	NN
cord-320092-0qnvydux	272	5	-	-	HYPH
cord-320092-0qnvydux	272	6	infection	infection	NN
cord-320092-0qnvydux	272	7	axis	axis	NN
cord-320092-0qnvydux	273	1	The	the	DT
cord-320092-0qnvydux	273	2	spike	spike	NN
cord-320092-0qnvydux	273	3	protein	protein	NN
cord-320092-0qnvydux	273	4	of	of	IN
cord-320092-0qnvydux	273	5	SARS	SARS	NNP
cord-320092-0qnvydux	273	6	-	-	HYPH
cord-320092-0qnvydux	273	7	CoV	CoV	NNP
cord-320092-0qnvydux	273	8	--	--	:
cord-320092-0qnvydux	273	9	a	a	DT
cord-320092-0qnvydux	273	10	target	target	NN
cord-320092-0qnvydux	273	11	for	for	IN
cord-320092-0qnvydux	273	12	vaccine	vaccine	NN
cord-320092-0qnvydux	273	13	and	and	CC
cord-320092-0qnvydux	273	14	therapeutic	therapeutic	JJ
cord-320092-0qnvydux	273	15	development	development	NN
cord-320092-0qnvydux	274	1	The	the	DT
cord-320092-0qnvydux	274	2	serine	serine	NN
cord-320092-0qnvydux	274	3	protease	protease	NN
cord-320092-0qnvydux	274	4	TMPR	TMPR	NNP
cord-320092-0qnvydux	274	5	SS6	SS6	NNP
cord-320092-0qnvydux	274	6	is	be	VBZ
cord-320092-0qnvydux	274	7	required	require	VBN
cord-320092-0qnvydux	274	8	to	to	TO
cord-320092-0qnvydux	274	9	sense	sense	VB
cord-320092-0qnvydux	274	10	iron	iron	NN
cord-320092-0qnvydux	274	11	deficiency	deficiency	NN
cord-320092-0qnvydux	275	1	Multisystem	Multisystem	NNP
cord-320092-0qnvydux	275	2	inflammatory	inflammatory	JJ
cord-320092-0qnvydux	275	3	syndrome	syndrome	NN
cord-320092-0qnvydux	275	4	in	in	IN
cord-320092-0qnvydux	275	5	children	child	NNS
cord-320092-0qnvydux	275	6	in	in	IN
cord-320092-0qnvydux	275	7	New	New	NNP
cord-320092-0qnvydux	275	8	York	York	NNP
cord-320092-0qnvydux	275	9	state	state	NN
cord-320092-0qnvydux	275	10	Lack	Lack	NNP
cord-320092-0qnvydux	275	11	of	of	IN
cord-320092-0qnvydux	275	12	association	association	NN
cord-320092-0qnvydux	275	13	between	between	IN
cord-320092-0qnvydux	275	14	New	New	NNP
cord-320092-0qnvydux	275	15	Haven	Haven	NNP
cord-320092-0qnvydux	275	16	coronavirus	coronavirus	NN
cord-320092-0qnvydux	275	17	and	and	CC
cord-320092-0qnvydux	275	18	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	275	19	disease	disease	NN
cord-320092-0qnvydux	275	20	Iron	iron	NN
cord-320092-0qnvydux	275	21	:	:	:
cord-320092-0qnvydux	275	22	innocent	innocent	JJ
cord-320092-0qnvydux	275	23	bystander	bystander	NN
cord-320092-0qnvydux	275	24	or	or	CC
cord-320092-0qnvydux	275	25	vicious	vicious	JJ
cord-320092-0qnvydux	275	26	culprit	culprit	NN
cord-320092-0qnvydux	275	27	in	in	IN
cord-320092-0qnvydux	275	28	COVID-19	covid-19	JJ
cord-320092-0qnvydux	275	29	pathogenesis	pathogenesis	NN
cord-320092-0qnvydux	275	30	?	?	.
cord-320092-0qnvydux	276	1	Macro	macro	NN
cord-320092-0qnvydux	276	2	-	-	HYPH
cord-320092-0qnvydux	276	3	trends	trend	NNS
cord-320092-0qnvydux	276	4	in	in	IN
cord-320092-0qnvydux	276	5	research	research	NN
cord-320092-0qnvydux	276	6	on	on	IN
cord-320092-0qnvydux	276	7	the	the	DT
cord-320092-0qnvydux	276	8	central	central	JJ
cord-320092-0qnvydux	276	9	dogma	dogma	NN
cord-320092-0qnvydux	276	10	of	of	IN
cord-320092-0qnvydux	276	11	molecular	molecular	JJ
cord-320092-0qnvydux	276	12	biology	biology	NN
cord-320092-0qnvydux	276	13	Identification	identification	NN
cord-320092-0qnvydux	276	14	of	of	IN
cord-320092-0qnvydux	276	15	the	the	DT
cord-320092-0qnvydux	276	16	Zeo1	Zeo1	NNP
cord-320092-0qnvydux	276	17	protein	protein	NN
cord-320092-0qnvydux	276	18	as	as	IN
cord-320092-0qnvydux	276	19	a	a	DT
cord-320092-0qnvydux	276	20	candidate	candidate	NN
cord-320092-0qnvydux	276	21	structural	structural	JJ
cord-320092-0qnvydux	276	22	homolog	homolog	NN
cord-320092-0qnvydux	276	23	of	of	IN
cord-320092-0qnvydux	276	24	α	α	NNP
cord-320092-0qnvydux	276	25	-	-	HYPH
cord-320092-0qnvydux	276	26	synuclein	synuclein	NNP
cord-320092-0qnvydux	276	27	in	in	IN
cord-320092-0qnvydux	276	28	budding	bud	VBG
cord-320092-0qnvydux	276	29	yeast	yeast	NN
cord-320092-0qnvydux	276	30	Evidence	evidence	NN
cord-320092-0qnvydux	276	31	for	for	IN
cord-320092-0qnvydux	276	32	retrogene	retrogene	JJ
cord-320092-0qnvydux	276	33	origins	origin	NNS
cord-320092-0qnvydux	276	34	of	of	IN
cord-320092-0qnvydux	276	35	the	the	DT
cord-320092-0qnvydux	276	36	prion	prion	NN
cord-320092-0qnvydux	276	37	gene	gene	NN
cord-320092-0qnvydux	276	38	family	family	NN
cord-320092-0qnvydux	276	39	Association	Association	NNP
cord-320092-0qnvydux	276	40	between	between	IN
cord-320092-0qnvydux	276	41	a	a	DT
cord-320092-0qnvydux	276	42	novel	novel	JJ
cord-320092-0qnvydux	276	43	human	human	JJ
cord-320092-0qnvydux	276	44	coronavirus	coronavirus	NN
cord-320092-0qnvydux	276	45	and	and	CC
cord-320092-0qnvydux	276	46	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	276	47	disease	disease	NN
cord-320092-0qnvydux	276	48	Multisystem	Multisystem	NNP
cord-320092-0qnvydux	276	49	inflammatory	inflammatory	JJ
cord-320092-0qnvydux	276	50	syndrome	syndrome	NN
cord-320092-0qnvydux	276	51	in	in	IN
cord-320092-0qnvydux	276	52	U.S.	U.S.	NNP
cord-320092-0qnvydux	276	53	children	child	NNS
cord-320092-0qnvydux	276	54	and	and	CC
cord-320092-0qnvydux	276	55	adolescents	adolescent	NNS
cord-320092-0qnvydux	276	56	Low	Low	NNP
cord-320092-0qnvydux	276	57	serum	serum	NN
cord-320092-0qnvydux	276	58	iron	iron	NN
cord-320092-0qnvydux	276	59	in	in	IN
cord-320092-0qnvydux	276	60	influenza	influenza	NN
cord-320092-0qnvydux	277	1	The	the	DT
cord-320092-0qnvydux	277	2	Pfam	Pfam	NNP
cord-320092-0qnvydux	277	3	protein	protein	NN
cord-320092-0qnvydux	277	4	families	family	NNS
cord-320092-0qnvydux	277	5	database	database	VBP
cord-320092-0qnvydux	277	6	Toward	toward	IN
cord-320092-0qnvydux	277	7	the	the	DT
cord-320092-0qnvydux	277	8	identification	identification	NN
cord-320092-0qnvydux	277	9	of	of	IN
cord-320092-0qnvydux	277	10	ZDHHC	ZDHHC	NNP
cord-320092-0qnvydux	277	11	enzymes	enzyme	NNS
cord-320092-0qnvydux	277	12	required	require	VBN
cord-320092-0qnvydux	277	13	for	for	IN
cord-320092-0qnvydux	277	14	palmitoylation	palmitoylation	NN
cord-320092-0qnvydux	277	15	of	of	IN
cord-320092-0qnvydux	277	16	viral	viral	JJ
cord-320092-0qnvydux	277	17	protein	protein	NN
cord-320092-0qnvydux	277	18	as	as	IN
cord-320092-0qnvydux	277	19	potential	potential	JJ
cord-320092-0qnvydux	277	20	drug	drug	NN
cord-320092-0qnvydux	277	21	targets	target	NNS
cord-320092-0qnvydux	277	22	Serum	serum	NN
cord-320092-0qnvydux	277	23	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	277	24	:	:	:
cord-320092-0qnvydux	278	1	reference	reference	NN
cord-320092-0qnvydux	278	2	ranges	range	NNS
cord-320092-0qnvydux	278	3	and	and	CC
cord-320092-0qnvydux	278	4	biochemical	biochemical	JJ
cord-320092-0qnvydux	278	5	correlates	correlate	NNS
cord-320092-0qnvydux	278	6	in	in	IN
cord-320092-0qnvydux	278	7	the	the	DT
cord-320092-0qnvydux	278	8	general	general	JJ
cord-320092-0qnvydux	278	9	population	population	NN
cord-320092-0qnvydux	279	1	Does	do	VBZ
cord-320092-0qnvydux	279	2	pathological	pathological	JJ
cord-320092-0qnvydux	279	3	iron	iron	NN
cord-320092-0qnvydux	279	4	overload	overload	NN
cord-320092-0qnvydux	279	5	impair	impair	VBP
cord-320092-0qnvydux	279	6	the	the	DT
cord-320092-0qnvydux	279	7	function	function	NN
cord-320092-0qnvydux	279	8	of	of	IN
cord-320092-0qnvydux	279	9	human	human	JJ
cord-320092-0qnvydux	279	10	lungs	lung	NNS
cord-320092-0qnvydux	279	11	?	?	.
cord-320092-0qnvydux	280	1	Anemia	anemia	NN
cord-320092-0qnvydux	280	2	of	of	IN
cord-320092-0qnvydux	280	3	inflammation	inflammation	NN
cord-320092-0qnvydux	280	4	Iron	iron	NN
cord-320092-0qnvydux	280	5	imports	import	NNS
cord-320092-0qnvydux	280	6	.	.	.
cord-320092-0qnvydux	281	1	IV	IV	NNP
cord-320092-0qnvydux	281	2	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	281	3	and	and	CC
cord-320092-0qnvydux	281	4	regulation	regulation	NN
cord-320092-0qnvydux	281	5	of	of	IN
cord-320092-0qnvydux	281	6	body	body	NN
cord-320092-0qnvydux	281	7	iron	iron	NN
cord-320092-0qnvydux	281	8	metabolism	metabolism	NN
cord-320092-0qnvydux	281	9	Iron	Iron	NNP
cord-320092-0qnvydux	281	10	chelation	chelation	NN
cord-320092-0qnvydux	281	11	may	may	MD
cord-320092-0qnvydux	281	12	harm	harm	VB
cord-320092-0qnvydux	281	13	patients	patient	NNS
cord-320092-0qnvydux	281	14	with	with	IN
cord-320092-0qnvydux	281	15	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	281	16	A	a	DT
cord-320092-0qnvydux	281	17	mechanistic	mechanistic	JJ
cord-320092-0qnvydux	281	18	model	model	NN
cord-320092-0qnvydux	281	19	and	and	CC
cord-320092-0qnvydux	281	20	therapeutic	therapeutic	JJ
cord-320092-0qnvydux	281	21	interventions	intervention	NNS
cord-320092-0qnvydux	281	22	for	for	IN
cord-320092-0qnvydux	281	23	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	281	24	involving	involve	VBG
cord-320092-0qnvydux	281	25	a	a	DT
cord-320092-0qnvydux	281	26	RAS	RAS	NNP
cord-320092-0qnvydux	281	27	-	-	HYPH
cord-320092-0qnvydux	281	28	mediated	mediate	VBN
cord-320092-0qnvydux	281	29	bradykinin	bradykinin	NN
cord-320092-0qnvydux	281	30	storm	storm	NN
cord-320092-0qnvydux	282	1	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	282	2	does	do	VBZ
cord-320092-0qnvydux	282	3	not	not	RB
cord-320092-0qnvydux	282	4	Lead	lead	VB
cord-320092-0qnvydux	282	5	to	to	IN
cord-320092-0qnvydux	282	6	a	a	DT
cord-320092-0qnvydux	282	7	"	"	``
cord-320092-0qnvydux	282	8	typical	typical	JJ
cord-320092-0qnvydux	282	9	"	"	''
cord-320092-0qnvydux	282	10	acute	acute	JJ
cord-320092-0qnvydux	282	11	respiratory	respiratory	JJ
cord-320092-0qnvydux	282	12	distress	distress	NN
cord-320092-0qnvydux	282	13	syndrome	syndrome	NN
cord-320092-0qnvydux	282	14	Biochemical	biochemical	JJ
cord-320092-0qnvydux	282	15	and	and	CC
cord-320092-0qnvydux	282	16	molecular	molecular	JJ
cord-320092-0qnvydux	282	17	identification	identification	NN
cord-320092-0qnvydux	282	18	of	of	IN
cord-320092-0qnvydux	282	19	a	a	DT
cord-320092-0qnvydux	282	20	novel	novel	JJ
cord-320092-0qnvydux	282	21	hepcidin	hepcidin	NN
cord-320092-0qnvydux	282	22	type	type	NN
cord-320092-0qnvydux	282	23	2-like	2-like	CD
cord-320092-0qnvydux	282	24	antimicrobial	antimicrobial	JJ
cord-320092-0qnvydux	282	25	peptide	peptide	NN
cord-320092-0qnvydux	282	26	in	in	IN
cord-320092-0qnvydux	282	27	the	the	DT
cord-320092-0qnvydux	282	28	skin	skin	NN
cord-320092-0qnvydux	282	29	mucus	mucus	NN
cord-320092-0qnvydux	282	30	of	of	IN
cord-320092-0qnvydux	282	31	the	the	DT
cord-320092-0qnvydux	282	32	pufferfish	pufferfish	NN
cord-320092-0qnvydux	282	33	Takifugu	Takifugu	NNP
cord-320092-0qnvydux	282	34	pardalis	pardali	VBD
cord-320092-0qnvydux	282	35	Hyperferritinemia	Hyperferritinemia	NNP
cord-320092-0qnvydux	282	36	in	in	IN
cord-320092-0qnvydux	282	37	critically	critically	RB
cord-320092-0qnvydux	282	38	ill	ill	JJ
cord-320092-0qnvydux	282	39	COVID-19	covid-19	CD
cord-320092-0qnvydux	282	40	patients	patient	NNS
cord-320092-0qnvydux	282	41	-is	-is	NFP
cord-320092-0qnvydux	282	42	ferritin	ferritin	NNS
cord-320092-0qnvydux	282	43	the	the	DT
cord-320092-0qnvydux	282	44	product	product	NN
cord-320092-0qnvydux	282	45	of	of	IN
cord-320092-0qnvydux	282	46	inflammation	inflammation	NN
cord-320092-0qnvydux	282	47	or	or	CC
cord-320092-0qnvydux	282	48	a	a	DT
cord-320092-0qnvydux	282	49	pathogenic	pathogenic	JJ
cord-320092-0qnvydux	282	50	mediator	mediator	NN
cord-320092-0qnvydux	282	51	?	?	.
cord-320092-0qnvydux	283	1	Novo	Novo	NNP
cord-320092-0qnvydux	283	2	-	-	HYPH
cord-320092-0qnvydux	283	3	backed	back	VBN
cord-320092-0qnvydux	283	4	biotech	biotech	JJ
cord-320092-0qnvydux	283	5	reels	reel	NNS
cord-320092-0qnvydux	283	6	in	in	IN
cord-320092-0qnvydux	283	7	ex	ex	NNP
cord-320092-0qnvydux	283	8	-	-	JJ
cord-320092-0qnvydux	283	9	Nimbus	Nimbus	NNP
cord-320092-0qnvydux	283	10	CEO	CEO	NNP
cord-320092-0qnvydux	283	11	Don	Don	NNP
cord-320092-0qnvydux	283	12	Nicholson	Nicholson	NNP
cord-320092-0qnvydux	283	13	as	as	IN
cord-320092-0qnvydux	283	14	exec	exec	NN
cord-320092-0qnvydux	283	15	chairman	chairman	NN
cord-320092-0qnvydux	283	16	,	,	,
cord-320092-0qnvydux	283	17	hooks	hook	VBZ
cord-320092-0qnvydux	283	18	$	$	$
cord-320092-0qnvydux	283	19	50	50	CD
cord-320092-0qnvydux	283	20	M	M	NNP
cord-320092-0qnvydux	283	21	to	to	TO
cord-320092-0qnvydux	283	22	conquer	conquer	VB
cord-320092-0qnvydux	283	23	anemia	anemia	NN
cord-320092-0qnvydux	283	24	.	.	.
cord-320092-0qnvydux	284	1	Endpoints	Endpoints	NNP
cord-320092-0qnvydux	284	2	News	News	NNP
cord-320092-0qnvydux	284	3	Genomic	Genomic	NNP
cord-320092-0qnvydux	284	4	determinants	determinant	NNS
cord-320092-0qnvydux	284	5	of	of	IN
cord-320092-0qnvydux	284	6	pathogenicity	pathogenicity	NN
cord-320092-0qnvydux	284	7	in	in	IN
cord-320092-0qnvydux	284	8	SARS	SARS	NNP
cord-320092-0qnvydux	284	9	-	-	HYPH
cord-320092-0qnvydux	284	10	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	284	11	and	and	CC
cord-320092-0qnvydux	284	12	other	other	JJ
cord-320092-0qnvydux	284	13	human	human	JJ
cord-320092-0qnvydux	284	14	coronaviruses	coronaviruse	NNS
cord-320092-0qnvydux	284	15	High	high	JJ
cord-320092-0qnvydux	284	16	-	-	HYPH
cord-320092-0qnvydux	284	17	altitude	altitude	NN
cord-320092-0qnvydux	284	18	acclimatization	acclimatization	NN
cord-320092-0qnvydux	284	19	suppresses	suppress	VBZ
cord-320092-0qnvydux	284	20	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	284	21	expression	expression	NN
cord-320092-0qnvydux	284	22	during	during	IN
cord-320092-0qnvydux	285	1	severe	severe	JJ
cord-320092-0qnvydux	285	2	energy	energy	NN
cord-320092-0qnvydux	285	3	deficit	deficit	NN
cord-320092-0qnvydux	285	4	Hypoferremia	Hypoferremia	NNP
cord-320092-0qnvydux	285	5	predicts	predict	VBZ
cord-320092-0qnvydux	285	6	hospitalization	hospitalization	NN
cord-320092-0qnvydux	285	7	and	and	CC
cord-320092-0qnvydux	285	8	oxygen	oxygen	NN
cord-320092-0qnvydux	285	9	demand	demand	NN
cord-320092-0qnvydux	285	10	in	in	IN
cord-320092-0qnvydux	285	11	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	285	12	patients	patient	NNS
cord-320092-0qnvydux	285	13	HAMP	HAMP	NNP
cord-320092-0qnvydux	285	14	promoter	promoter	NN
cord-320092-0qnvydux	285	15	hypomethylation	hypomethylation	NN
cord-320092-0qnvydux	285	16	and	and	CC
cord-320092-0qnvydux	285	17	increased	increase	VBN
cord-320092-0qnvydux	285	18	hepcidin	hepcidin	NN
cord-320092-0qnvydux	285	19	levels	level	NNS
cord-320092-0qnvydux	285	20	as	as	IN
cord-320092-0qnvydux	285	21	biomarkers	biomarker	NNS
cord-320092-0qnvydux	285	22	for	for	IN
cord-320092-0qnvydux	285	23	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	285	24	disease	disease	NN
cord-320092-0qnvydux	285	25	Human	Human	NNP
cord-320092-0qnvydux	285	26	coronaviruses	coronaviruse	NNS
cord-320092-0qnvydux	285	27	OC43	OC43	NNP
cord-320092-0qnvydux	285	28	and	and	CC
cord-320092-0qnvydux	285	29	HKU1	HKU1	NNP
cord-320092-0qnvydux	285	30	bind	bind	VBP
cord-320092-0qnvydux	285	31	to	to	IN
cord-320092-0qnvydux	285	32	9-O	9-o	CD
cord-320092-0qnvydux	285	33	-	-	HYPH
cord-320092-0qnvydux	285	34	acetylated	acetylated	JJ
cord-320092-0qnvydux	285	35	sialic	sialic	NN
cord-320092-0qnvydux	285	36	acids	acid	NNS
cord-320092-0qnvydux	285	37	via	via	IN
cord-320092-0qnvydux	285	38	a	a	DT
cord-320092-0qnvydux	285	39	conserved	conserve	VBN
cord-320092-0qnvydux	285	40	receptor	receptor	NN
cord-320092-0qnvydux	285	41	-	-	HYPH
cord-320092-0qnvydux	285	42	binding	bind	VBG
cord-320092-0qnvydux	285	43	site	site	NN
cord-320092-0qnvydux	285	44	in	in	IN
cord-320092-0qnvydux	285	45	spike	spike	NN
cord-320092-0qnvydux	285	46	protein	protein	NN
cord-320092-0qnvydux	285	47	domain	domain	NN
cord-320092-0qnvydux	286	1	a	a	DT
cord-320092-0qnvydux	286	2	The	the	DT
cord-320092-0qnvydux	286	3	solution	solution	NN
cord-320092-0qnvydux	286	4	structure	structure	NN
cord-320092-0qnvydux	286	5	of	of	IN
cord-320092-0qnvydux	286	6	human	human	JJ
cord-320092-0qnvydux	286	7	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	286	8	,	,	,
cord-320092-0qnvydux	286	9	a	a	DT
cord-320092-0qnvydux	286	10	peptide	peptide	JJ
cord-320092-0qnvydux	286	11	hormone	hormone	NN
cord-320092-0qnvydux	286	12	with	with	IN
cord-320092-0qnvydux	286	13	antimicrobial	antimicrobial	JJ
cord-320092-0qnvydux	286	14	activity	activity	NN
cord-320092-0qnvydux	286	15	that	that	WDT
cord-320092-0qnvydux	286	16	is	be	VBZ
cord-320092-0qnvydux	286	17	involved	involve	VBN
cord-320092-0qnvydux	286	18	in	in	IN
cord-320092-0qnvydux	286	19	iron	iron	NN
cord-320092-0qnvydux	286	20	uptake	uptake	NN
cord-320092-0qnvydux	286	21	and	and	CC
cord-320092-0qnvydux	286	22	hereditary	hereditary	JJ
cord-320092-0qnvydux	286	23	hemochromatosis	hemochromatosis	NN
cord-320092-0qnvydux	287	1	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	287	2	and	and	CC
cord-320092-0qnvydux	287	3	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	287	4	disease	disease	NN
cord-320092-0qnvydux	287	5	:	:	:
cord-320092-0qnvydux	288	1	novel	novel	JJ
cord-320092-0qnvydux	288	2	virus	virus	NN
cord-320092-0qnvydux	288	3	and	and	CC
cord-320092-0qnvydux	288	4	novel	novel	NN
cord-320092-0qnvydux	288	5	case	case	NN
cord-320092-0qnvydux	289	1	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	289	2	revisited	revisit	VBD
cord-320092-0qnvydux	289	3	,	,	,
cord-320092-0qnvydux	289	4	disulfide	disulfide	JJ
cord-320092-0qnvydux	289	5	connectivity	connectivity	NN
cord-320092-0qnvydux	289	6	,	,	,
cord-320092-0qnvydux	289	7	dynamics	dynamic	NNS
cord-320092-0qnvydux	289	8	,	,	,
cord-320092-0qnvydux	289	9	and	and	CC
cord-320092-0qnvydux	289	10	structure	structure	NN
cord-320092-0qnvydux	289	11	Mechanisms	Mechanisms	NNPS
cord-320092-0qnvydux	289	12	of	of	IN
cord-320092-0qnvydux	289	13	virus	virus	NN
cord-320092-0qnvydux	289	14	membrane	membrane	NN
cord-320092-0qnvydux	289	15	fusion	fusion	NN
cord-320092-0qnvydux	289	16	proteins	protein	NNS
cord-320092-0qnvydux	290	1	Chondrostean	chondrostean	JJ
cord-320092-0qnvydux	290	2	sturgeon	sturgeon	NN
cord-320092-0qnvydux	290	3	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	290	4	:	:	:
cord-320092-0qnvydux	290	5	an	an	DT
cord-320092-0qnvydux	290	6	evolutionary	evolutionary	JJ
cord-320092-0qnvydux	290	7	link	link	NN
cord-320092-0qnvydux	290	8	between	between	IN
cord-320092-0qnvydux	291	1	teleost	teleost	NN
cord-320092-0qnvydux	291	2	and	and	CC
cord-320092-0qnvydux	291	3	tetrapod	tetrapod	NN
cord-320092-0qnvydux	291	4	hepcidins	hepcidins	NNP
cord-320092-0qnvydux	291	5	Tracking	track	VBG
cord-320092-0qnvydux	291	6	changes	change	NNS
cord-320092-0qnvydux	291	7	in	in	IN
cord-320092-0qnvydux	291	8	SARS	SARS	NNP
cord-320092-0qnvydux	291	9	-	-	HYPH
cord-320092-0qnvydux	291	10	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	291	11	spike	spike	NN
cord-320092-0qnvydux	291	12	:	:	:
cord-320092-0qnvydux	291	13	evidence	evidence	NN
cord-320092-0qnvydux	291	14	that	that	IN
cord-320092-0qnvydux	291	15	D614	d614	CD
cord-320092-0qnvydux	291	16	G	g	NN
cord-320092-0qnvydux	291	17	increases	increase	VBZ
cord-320092-0qnvydux	291	18	infectivity	infectivity	NN
cord-320092-0qnvydux	291	19	of	of	IN
cord-320092-0qnvydux	291	20	the	the	DT
cord-320092-0qnvydux	291	21	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	291	22	virus	virus	NN
cord-320092-0qnvydux	291	23	LEAP-1	LEAP-1	NNP
cord-320092-0qnvydux	291	24	,	,	,
cord-320092-0qnvydux	291	25	a	a	DT
cord-320092-0qnvydux	291	26	novel	novel	NN
cord-320092-0qnvydux	291	27	highly	highly	RB
cord-320092-0qnvydux	291	28	disulfide	disulfide	RB
cord-320092-0qnvydux	291	29	-	-	HYPH
cord-320092-0qnvydux	291	30	bonded	bond	VBN
cord-320092-0qnvydux	291	31	human	human	JJ
cord-320092-0qnvydux	291	32	peptide	peptide	NN
cord-320092-0qnvydux	291	33	,	,	,
cord-320092-0qnvydux	291	34	exhibits	exhibit	VBZ
cord-320092-0qnvydux	291	35	antimicrobial	antimicrobial	JJ
cord-320092-0qnvydux	291	36	activity	activity	NN
cord-320092-0qnvydux	292	1	A	a	DT
cord-320092-0qnvydux	292	2	dynamic	dynamic	JJ
cord-320092-0qnvydux	292	3	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	292	4	immune	immune	JJ
cord-320092-0qnvydux	292	5	signature	signature	NN
cord-320092-0qnvydux	292	6	includes	include	VBZ
cord-320092-0qnvydux	292	7	associations	association	NNS
cord-320092-0qnvydux	292	8	with	with	IN
cord-320092-0qnvydux	292	9	poor	poor	JJ
cord-320092-0qnvydux	292	10	prognosis	prognosis	NN
cord-320092-0qnvydux	293	1	Intracellular	Intracellular	NNP
cord-320092-0qnvydux	293	2	iron	iron	NN
cord-320092-0qnvydux	293	3	deficiency	deficiency	NN
cord-320092-0qnvydux	293	4	in	in	IN
cord-320092-0qnvydux	293	5	pulmonary	pulmonary	JJ
cord-320092-0qnvydux	293	6	arterial	arterial	JJ
cord-320092-0qnvydux	293	7	smooth	smooth	JJ
cord-320092-0qnvydux	293	8	muscle	muscle	NN
cord-320092-0qnvydux	293	9	cells	cell	NNS
cord-320092-0qnvydux	293	10	induces	induce	VBZ
cord-320092-0qnvydux	293	11	pulmonary	pulmonary	JJ
cord-320092-0qnvydux	293	12	arterial	arterial	JJ
cord-320092-0qnvydux	293	13	hypertension	hypertension	NN
cord-320092-0qnvydux	293	14	in	in	IN
cord-320092-0qnvydux	293	15	mice	mouse	NNS
cord-320092-0qnvydux	293	16	Bass	Bass	NNP
cord-320092-0qnvydux	293	17	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	293	18	synthesis	synthesis	NN
cord-320092-0qnvydux	293	19	,	,	,
cord-320092-0qnvydux	293	20	solution	solution	NN
cord-320092-0qnvydux	293	21	structure	structure	NN
cord-320092-0qnvydux	293	22	,	,	,
cord-320092-0qnvydux	293	23	antimicrobial	antimicrobial	JJ
cord-320092-0qnvydux	293	24	activities	activity	NNS
cord-320092-0qnvydux	293	25	and	and	CC
cord-320092-0qnvydux	293	26	synergism	synergism	NN
cord-320092-0qnvydux	293	27	,	,	,
cord-320092-0qnvydux	293	28	and	and	CC
cord-320092-0qnvydux	293	29	in	in	IN
cord-320092-0qnvydux	293	30	vivo	vivo	FW
cord-320092-0qnvydux	293	31	hepatic	hepatic	JJ
cord-320092-0qnvydux	293	32	response	response	NN
cord-320092-0qnvydux	293	33	to	to	IN
cord-320092-0qnvydux	293	34	bacterial	bacterial	JJ
cord-320092-0qnvydux	293	35	infections	infection	NNS
cord-320092-0qnvydux	293	36	Post	post	JJ
cord-320092-0qnvydux	293	37	-	-	JJ
cord-320092-0qnvydux	293	38	translational	translational	JJ
cord-320092-0qnvydux	293	39	processing	processing	NN
cord-320092-0qnvydux	293	40	of	of	IN
cord-320092-0qnvydux	293	41	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	293	42	in	in	IN
cord-320092-0qnvydux	293	43	human	human	JJ
cord-320092-0qnvydux	293	44	hepatocytes	hepatocyte	NNS
cord-320092-0qnvydux	293	45	is	be	VBZ
cord-320092-0qnvydux	293	46	mediated	mediate	VBN
cord-320092-0qnvydux	293	47	by	by	IN
cord-320092-0qnvydux	293	48	the	the	DT
cord-320092-0qnvydux	293	49	prohormone	prohormone	NN
cord-320092-0qnvydux	293	50	convertase	convertase	NN
cord-320092-0qnvydux	293	51	furin	furin	NN
cord-320092-0qnvydux	293	52	Hepatobiliary	Hepatobiliary	NNP
cord-320092-0qnvydux	293	53	pathology	pathology	NN
cord-320092-0qnvydux	293	54	Structure	Structure	NNP
cord-320092-0qnvydux	293	55	,	,	,
cord-320092-0qnvydux	293	56	function	function	NN
cord-320092-0qnvydux	293	57	,	,	,
cord-320092-0qnvydux	293	58	and	and	CC
cord-320092-0qnvydux	293	59	evolution	evolution	NN
cord-320092-0qnvydux	293	60	of	of	IN
cord-320092-0qnvydux	293	61	coronavirus	coronavirus	NN
cord-320092-0qnvydux	293	62	spike	spike	NN
cord-320092-0qnvydux	293	63	proteins	protein	NNS
cord-320092-0qnvydux	293	64	Rethinking	rethink	VBG
cord-320092-0qnvydux	293	65	living	live	VBG
cord-320092-0qnvydux	293	66	fossils	fossil	NNS
cord-320092-0qnvydux	294	1	Palmitoylation	Palmitoylation	NNP
cord-320092-0qnvydux	294	2	:	:	:
cord-320092-0qnvydux	294	3	policing	police	VBG
cord-320092-0qnvydux	294	4	protein	protein	NN
cord-320092-0qnvydux	294	5	stability	stability	NN
cord-320092-0qnvydux	294	6	and	and	CC
cord-320092-0qnvydux	294	7	traffic	traffic	NN
cord-320092-0qnvydux	294	8	Characterization	characterization	NN
cord-320092-0qnvydux	294	9	and	and	CC
cord-320092-0qnvydux	294	10	functional	functional	JJ
cord-320092-0qnvydux	294	11	analysis	analysis	NN
cord-320092-0qnvydux	294	12	of	of	IN
cord-320092-0qnvydux	294	13	liver	liver	NN
cord-320092-0qnvydux	294	14	-	-	HYPH
cord-320092-0qnvydux	294	15	expressed	express	VBN
cord-320092-0qnvydux	294	16	antimicrobial	antimicrobial	JJ
cord-320092-0qnvydux	294	17	peptide-2	peptide-2	NNP
cord-320092-0qnvydux	294	18	(	(	-LRB-
cord-320092-0qnvydux	294	19	LEAP-2	LEAP-2	NNP
cord-320092-0qnvydux	294	20	)	)	-RRB-
cord-320092-0qnvydux	294	21	from	from	IN
cord-320092-0qnvydux	294	22	golden	golden	NNP
cord-320092-0qnvydux	294	23	pompano	pompano	NNP
cord-320092-0qnvydux	294	24	Trachinotus	Trachinotus	NNP
cord-320092-0qnvydux	294	25	ovatus	ovatus	NN
cord-320092-0qnvydux	294	26	(	(	-LRB-
cord-320092-0qnvydux	294	27	Linnaeus	Linnaeus	NNP
cord-320092-0qnvydux	294	28	1758	1758	CD
cord-320092-0qnvydux	294	29	)	)	-RRB-
cord-320092-0qnvydux	295	1	Depriving	deprive	VBG
cord-320092-0qnvydux	295	2	iron	iron	NN
cord-320092-0qnvydux	295	3	supply	supply	NN
cord-320092-0qnvydux	295	4	to	to	IN
cord-320092-0qnvydux	295	5	the	the	DT
cord-320092-0qnvydux	295	6	virus	virus	NN
cord-320092-0qnvydux	295	7	represents	represent	VBZ
cord-320092-0qnvydux	295	8	a	a	DT
cord-320092-0qnvydux	295	9	promising	promising	JJ
cord-320092-0qnvydux	295	10	adjuvant	adjuvant	NN
cord-320092-0qnvydux	295	11	therapeutic	therapeutic	JJ
cord-320092-0qnvydux	295	12	against	against	IN
cord-320092-0qnvydux	295	13	The	the	DT
cord-320092-0qnvydux	295	14	cytoplasmic	cytoplasmic	JJ
cord-320092-0qnvydux	295	15	tail	tail	NN
cord-320092-0qnvydux	295	16	of	of	IN
cord-320092-0qnvydux	295	17	the	the	DT
cord-320092-0qnvydux	295	18	severe	severe	JJ
cord-320092-0qnvydux	295	19	acute	acute	JJ
cord-320092-0qnvydux	295	20	respiratory	respiratory	JJ
cord-320092-0qnvydux	295	21	syndrome	syndrome	NN
cord-320092-0qnvydux	295	22	coronavirus	coronavirus	NN
cord-320092-0qnvydux	295	23	spike	spike	NN
cord-320092-0qnvydux	295	24	protein	protein	NN
cord-320092-0qnvydux	296	1	contains	contain	VBZ
cord-320092-0qnvydux	296	2	a	a	DT
cord-320092-0qnvydux	296	3	novel	novel	JJ
cord-320092-0qnvydux	296	4	endoplasmic	endoplasmic	NN
cord-320092-0qnvydux	296	5	reticulum	reticulum	NN
cord-320092-0qnvydux	296	6	retrieval	retrieval	NN
cord-320092-0qnvydux	296	7	signal	signal	NN
cord-320092-0qnvydux	296	8	that	that	WDT
cord-320092-0qnvydux	296	9	binds	bind	VBZ
cord-320092-0qnvydux	296	10	COPI	COPI	NNP
cord-320092-0qnvydux	296	11	and	and	CC
cord-320092-0qnvydux	296	12	promotes	promote	VBZ
cord-320092-0qnvydux	296	13	interaction	interaction	NN
cord-320092-0qnvydux	296	14	with	with	IN
cord-320092-0qnvydux	296	15	membrane	membrane	NN
cord-320092-0qnvydux	296	16	protein	protein	NN
cord-320092-0qnvydux	297	1	Palmitoylation	Palmitoylation	NNP
cord-320092-0qnvydux	297	2	of	of	IN
cord-320092-0qnvydux	297	3	SARS	SARS	NNP
cord-320092-0qnvydux	297	4	-	-	HYPH
cord-320092-0qnvydux	297	5	CoV	CoV	NNP
cord-320092-0qnvydux	297	6	S	S	NNP
cord-320092-0qnvydux	297	7	protein	protein	NN
cord-320092-0qnvydux	297	8	is	be	VBZ
cord-320092-0qnvydux	297	9	necessary	necessary	JJ
cord-320092-0qnvydux	297	10	for	for	IN
cord-320092-0qnvydux	297	11	partitioning	partition	VBG
cord-320092-0qnvydux	297	12	into	into	IN
cord-320092-0qnvydux	297	13	detergent	detergent	NN
cord-320092-0qnvydux	297	14	-	-	HYPH
cord-320092-0qnvydux	297	15	resistant	resistant	JJ
cord-320092-0qnvydux	297	16	membranes	membrane	NNS
cord-320092-0qnvydux	297	17	and	and	CC
cord-320092-0qnvydux	297	18	cell	cell	NN
cord-320092-0qnvydux	297	19	-	-	HYPH
cord-320092-0qnvydux	297	20	cell	cell	NN
cord-320092-0qnvydux	297	21	fusion	fusion	NN
cord-320092-0qnvydux	297	22	but	but	CC
cord-320092-0qnvydux	297	23	not	not	RB
cord-320092-0qnvydux	297	24	interaction	interaction	NN
cord-320092-0qnvydux	297	25	with	with	IN
cord-320092-0qnvydux	297	26	M	M	NNP
cord-320092-0qnvydux	297	27	protein	protein	NN
cord-320092-0qnvydux	297	28	Coronavirus	Coronavirus	NNP
cord-320092-0qnvydux	297	29	infection	infection	NN
cord-320092-0qnvydux	297	30	in	in	IN
cord-320092-0qnvydux	297	31	acute	acute	JJ
cord-320092-0qnvydux	297	32	lower	low	JJR
cord-320092-0qnvydux	297	33	respiratory	respiratory	JJ
cord-320092-0qnvydux	297	34	tract	tract	NN
cord-320092-0qnvydux	297	35	disease	disease	NN
cord-320092-0qnvydux	297	36	of	of	IN
cord-320092-0qnvydux	297	37	infants	infant	NNS
cord-320092-0qnvydux	298	1	COVID-19-related	covid-19-related	JJ
cord-320092-0qnvydux	298	2	coagulopathy	coagulopathy	NN
cord-320092-0qnvydux	298	3	-	-	:
cord-320092-0qnvydux	298	4	is	be	VBZ
cord-320092-0qnvydux	298	5	transferrin	transferrin	NN
cord-320092-0qnvydux	298	6	a	a	DT
cord-320092-0qnvydux	298	7	missing	missing	JJ
cord-320092-0qnvydux	298	8	link	link	NN
cord-320092-0qnvydux	298	9	?	?	.
cord-320092-0qnvydux	299	1	Diagnostics	Diagnostics	NNP
cord-320092-0qnvydux	299	2	(	(	-LRB-
cord-320092-0qnvydux	299	3	Basel	Basel	NNP
cord-320092-0qnvydux	299	4	)	)	-RRB-
cord-320092-0qnvydux	299	5	COVID-19	covid-19	VBP
cord-320092-0qnvydux	299	6	:	:	:
cord-320092-0qnvydux	299	7	consider	consider	VB
cord-320092-0qnvydux	299	8	cytokine	cytokine	JJ
cord-320092-0qnvydux	299	9	storm	storm	NN
cord-320092-0qnvydux	299	10	syndromes	syndrome	NNS
cord-320092-0qnvydux	299	11	and	and	CC
cord-320092-0qnvydux	299	12	immunosuppression	immunosuppression	NN
cord-320092-0qnvydux	299	13	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	299	14	and	and	CC
cord-320092-0qnvydux	299	15	host	host	NN
cord-320092-0qnvydux	299	16	defense	defense	NN
cord-320092-0qnvydux	299	17	against	against	IN
cord-320092-0qnvydux	299	18	infectious	infectious	JJ
cord-320092-0qnvydux	299	19	diseases	disease	NNS
cord-320092-0qnvydux	300	1	COVID-19-associated	covid-19-associated	JJ
cord-320092-0qnvydux	300	2	cardiovascular	cardiovascular	JJ
cord-320092-0qnvydux	300	3	morbidity	morbidity	NN
cord-320092-0qnvydux	300	4	in	in	IN
cord-320092-0qnvydux	300	5	older	old	JJR
cord-320092-0qnvydux	300	6	adults	adult	NNS
cord-320092-0qnvydux	300	7	:	:	:
cord-320092-0qnvydux	300	8	a	a	DT
cord-320092-0qnvydux	300	9	position	position	NN
cord-320092-0qnvydux	300	10	paper	paper	NN
cord-320092-0qnvydux	300	11	from	from	IN
cord-320092-0qnvydux	300	12	the	the	DT
cord-320092-0qnvydux	300	13	Italian	Italian	NNP
cord-320092-0qnvydux	300	14	Society	Society	NNP
cord-320092-0qnvydux	300	15	of	of	IN
cord-320092-0qnvydux	300	16	Cardiovascular	Cardiovascular	NNP
cord-320092-0qnvydux	300	17	Researches	Researches	NNPS
cord-320092-0qnvydux	300	18	Cytokine	cytokine	NN
cord-320092-0qnvydux	300	19	release	release	NN
cord-320092-0qnvydux	300	20	syndrome	syndrome	NN
cord-320092-0qnvydux	300	21	in	in	IN
cord-320092-0qnvydux	300	22	severe	severe	JJ
cord-320092-0qnvydux	300	23	COVID-19	covid-19	NN
cord-320092-0qnvydux	301	1	The	the	DT
cord-320092-0qnvydux	301	2	ferroportin	ferroportin	NN
cord-320092-0qnvydux	301	3	Q248H	Q248H	NNP
cord-320092-0qnvydux	301	4	mutation	mutation	NN
cord-320092-0qnvydux	301	5	protects	protect	VBZ
cord-320092-0qnvydux	301	6	from	from	IN
cord-320092-0qnvydux	301	7	anemia	anemia	NN
cord-320092-0qnvydux	301	8	,	,	,
cord-320092-0qnvydux	301	9	but	but	CC
cord-320092-0qnvydux	301	10	not	not	RB
cord-320092-0qnvydux	301	11	malaria	malaria	NN
cord-320092-0qnvydux	301	12	or	or	CC
cord-320092-0qnvydux	301	13	bacteremia	bacteremia	NN
cord-320092-0qnvydux	302	1	The	the	DT
cord-320092-0qnvydux	302	2	role	role	NN
cord-320092-0qnvydux	302	3	of	of	IN
cord-320092-0qnvydux	302	4	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	302	5	in	in	IN
cord-320092-0qnvydux	302	6	iron	iron	NN
cord-320092-0qnvydux	302	7	metabolism	metabolism	NN
cord-320092-0qnvydux	302	8	Disruption	disruption	NN
cord-320092-0qnvydux	302	9	of	of	IN
cord-320092-0qnvydux	302	10	the	the	DT
cord-320092-0qnvydux	302	11	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	302	12	/	/	SYM
cord-320092-0qnvydux	302	13	Ferroportin	Ferroportin	NNP
cord-320092-0qnvydux	302	14	regulatory	regulatory	JJ
cord-320092-0qnvydux	302	15	system	system	NN
cord-320092-0qnvydux	302	16	causes	cause	VBZ
cord-320092-0qnvydux	302	17	pulmonary	pulmonary	JJ
cord-320092-0qnvydux	302	18	iron	iron	NN
cord-320092-0qnvydux	302	19	overload	overload	NN
cord-320092-0qnvydux	302	20	and	and	CC
cord-320092-0qnvydux	302	21	restrictive	restrictive	JJ
cord-320092-0qnvydux	302	22	lung	lung	NN
cord-320092-0qnvydux	302	23	disease	disease	NN
cord-320092-0qnvydux	303	1	Hamp1	Hamp1	NNP
cord-320092-0qnvydux	304	1	but	but	CC
cord-320092-0qnvydux	304	2	not	not	RB
cord-320092-0qnvydux	304	3	Hamp2	Hamp2	NNP
cord-320092-0qnvydux	304	4	regulates	regulate	VBZ
cord-320092-0qnvydux	304	5	ferroportin	ferroportin	NN
cord-320092-0qnvydux	304	6	in	in	IN
cord-320092-0qnvydux	304	7	fish	fish	NN
cord-320092-0qnvydux	304	8	with	with	IN
cord-320092-0qnvydux	304	9	two	two	CD
cord-320092-0qnvydux	304	10	functionally	functionally	RB
cord-320092-0qnvydux	304	11	distinct	distinct	JJ
cord-320092-0qnvydux	304	12	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	304	13	types	type	NNS
cord-320092-0qnvydux	304	14	The	the	DT
cord-320092-0qnvydux	304	15	gene	gene	NN
cord-320092-0qnvydux	304	16	encoding	encode	VBG
cord-320092-0qnvydux	304	17	the	the	DT
cord-320092-0qnvydux	304	18	iron	iron	NN
cord-320092-0qnvydux	304	19	regulatory	regulatory	JJ
cord-320092-0qnvydux	304	20	peptide	peptide	NN
cord-320092-0qnvydux	304	21	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	304	22	is	be	VBZ
cord-320092-0qnvydux	304	23	regulated	regulate	VBN
cord-320092-0qnvydux	304	24	by	by	IN
cord-320092-0qnvydux	304	25	anemia	anemia	NN
cord-320092-0qnvydux	304	26	,	,	,
cord-320092-0qnvydux	304	27	hypoxia	hypoxia	NN
cord-320092-0qnvydux	304	28	,	,	,
cord-320092-0qnvydux	304	29	and	and	CC
cord-320092-0qnvydux	304	30	inflammation	inflammation	NN
cord-320092-0qnvydux	304	31	Comparison	comparison	NN
cord-320092-0qnvydux	304	32	of	of	IN
cord-320092-0qnvydux	304	33	complete	complete	JJ
cord-320092-0qnvydux	304	34	amino	amino	NN
cord-320092-0qnvydux	304	35	acid	acid	NN
cord-320092-0qnvydux	304	36	sequences	sequence	NNS
cord-320092-0qnvydux	304	37	and	and	CC
cord-320092-0qnvydux	304	38	receptor	receptor	NN
cord-320092-0qnvydux	304	39	-	-	HYPH
cord-320092-0qnvydux	304	40	binding	bind	VBG
cord-320092-0qnvydux	304	41	properties	property	NNS
cord-320092-0qnvydux	304	42	among	among	IN
cord-320092-0qnvydux	304	43	13	13	CD
cord-320092-0qnvydux	304	44	serotypes	serotype	NNS
cord-320092-0qnvydux	304	45	of	of	IN
cord-320092-0qnvydux	304	46	hemagglutinins	hemagglutinin	NNS
cord-320092-0qnvydux	304	47	of	of	IN
cord-320092-0qnvydux	304	48	influenza	influenza	NN
cord-320092-0qnvydux	304	49	a	a	DT
cord-320092-0qnvydux	304	50	viruses	virus	NNS
cord-320092-0qnvydux	304	51	Treatment	treatment	NN
cord-320092-0qnvydux	304	52	with	with	IN
cord-320092-0qnvydux	304	53	anti	anti	JJ
cord-320092-0qnvydux	304	54	-	-	JJ
cord-320092-0qnvydux	304	55	IL-6	il-6	JJ
cord-320092-0qnvydux	304	56	receptor	receptor	NN
cord-320092-0qnvydux	304	57	antibody	antibody	NN
cord-320092-0qnvydux	304	58	prevented	prevent	VBD
cord-320092-0qnvydux	304	59	increase	increase	NN
cord-320092-0qnvydux	304	60	in	in	IN
cord-320092-0qnvydux	304	61	serum	serum	NN
cord-320092-0qnvydux	304	62	hepcidin	hepcidin	NNS
cord-320092-0qnvydux	304	63	levels	level	NNS
cord-320092-0qnvydux	304	64	and	and	CC
cord-320092-0qnvydux	304	65	improved	improved	JJ
cord-320092-0qnvydux	304	66	anemia	anemia	NN
cord-320092-0qnvydux	304	67	in	in	IN
cord-320092-0qnvydux	304	68	mice	mouse	NNS
cord-320092-0qnvydux	304	69	inoculated	inoculate	VBN
cord-320092-0qnvydux	304	70	with	with	IN
cord-320092-0qnvydux	304	71	IL-6-producing	il-6-produce	VBG
cord-320092-0qnvydux	304	72	lung	lung	NN
cord-320092-0qnvydux	304	73	carcinoma	carcinoma	NN
cord-320092-0qnvydux	304	74	cells	cell	VBZ
cord-320092-0qnvydux	304	75	Clinical	clinical	JJ
cord-320092-0qnvydux	304	76	characteristics	characteristic	NNS
cord-320092-0qnvydux	304	77	of	of	IN
cord-320092-0qnvydux	304	78	COVID-19	covid-19	JJ
cord-320092-0qnvydux	304	79	patients	patient	NNS
cord-320092-0qnvydux	304	80	with	with	IN
cord-320092-0qnvydux	304	81	digestive	digestive	JJ
cord-320092-0qnvydux	304	82	symptoms	symptom	NNS
cord-320092-0qnvydux	304	83	in	in	IN
cord-320092-0qnvydux	304	84	Hubei	Hubei	NNP
cord-320092-0qnvydux	304	85	,	,	,
cord-320092-0qnvydux	304	86	China	China	NNP
cord-320092-0qnvydux	304	87	:	:	:
cord-320092-0qnvydux	304	88	a	a	DT
cord-320092-0qnvydux	304	89	descriptive	descriptive	JJ
cord-320092-0qnvydux	304	90	,	,	,
cord-320092-0qnvydux	304	91	cross	cross	JJ
cord-320092-0qnvydux	304	92	-	-	JJ
cord-320092-0qnvydux	304	93	sectional	sectional	JJ
cord-320092-0qnvydux	304	94	,	,	,
cord-320092-0qnvydux	304	95	multicenter	multicenter	JJ
cord-320092-0qnvydux	304	96	study	study	NN
cord-320092-0qnvydux	304	97	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	304	98	,	,	,
cord-320092-0qnvydux	304	99	a	a	DT
cord-320092-0qnvydux	304	100	urinary	urinary	JJ
cord-320092-0qnvydux	304	101	antimicrobial	antimicrobial	JJ
cord-320092-0qnvydux	304	102	peptide	peptide	NN
cord-320092-0qnvydux	304	103	synthesized	synthesize	VBN
cord-320092-0qnvydux	304	104	in	in	IN
cord-320092-0qnvydux	304	105	the	the	DT
cord-320092-0qnvydux	304	106	liver	liver	NN
cord-320092-0qnvydux	304	107	Crystal	Crystal	NNP
cord-320092-0qnvydux	304	108	structure	structure	NN
cord-320092-0qnvydux	304	109	of	of	IN
cord-320092-0qnvydux	304	110	mouse	mouse	NN
cord-320092-0qnvydux	304	111	coronavirus	coronavirus	NN
cord-320092-0qnvydux	304	112	receptor	receptor	NN
cord-320092-0qnvydux	304	113	-	-	HYPH
cord-320092-0qnvydux	304	114	binding	bind	VBG
cord-320092-0qnvydux	304	115	domain	domain	NN
cord-320092-0qnvydux	304	116	complexed	complexe	VBN
cord-320092-0qnvydux	304	117	with	with	IN
cord-320092-0qnvydux	304	118	its	-PRON-	PRP$
cord-320092-0qnvydux	304	119	murine	murine	JJ
cord-320092-0qnvydux	304	120	receptor	receptor	NN
cord-320092-0qnvydux	305	1	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	305	2	is	be	VBZ
cord-320092-0qnvydux	305	3	essential	essential	JJ
cord-320092-0qnvydux	305	4	for	for	IN
cord-320092-0qnvydux	305	5	alveolar	alveolar	JJ
cord-320092-0qnvydux	305	6	macrophage	macrophage	NN
cord-320092-0qnvydux	305	7	function	function	NN
cord-320092-0qnvydux	305	8	and	and	CC
cord-320092-0qnvydux	305	9	is	be	VBZ
cord-320092-0qnvydux	305	10	disrupted	disrupt	VBN
cord-320092-0qnvydux	305	11	by	by	IN
cord-320092-0qnvydux	305	12	smoke	smoke	NN
cord-320092-0qnvydux	305	13	in	in	IN
cord-320092-0qnvydux	305	14	a	a	DT
cord-320092-0qnvydux	305	15	murine	murine	JJ
cord-320092-0qnvydux	305	16	chronic	chronic	JJ
cord-320092-0qnvydux	305	17	obstructive	obstructive	JJ
cord-320092-0qnvydux	305	18	pulmonary	pulmonary	JJ
cord-320092-0qnvydux	305	19	disease	disease	NN
cord-320092-0qnvydux	305	20	model	model	NN
cord-320092-0qnvydux	305	21	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	305	22	as	as	IN
cord-320092-0qnvydux	305	23	part	part	NN
cord-320092-0qnvydux	305	24	of	of	IN
cord-320092-0qnvydux	305	25	the	the	DT
cord-320092-0qnvydux	305	26	hyperferritinemic	hyperferritinemic	JJ
cord-320092-0qnvydux	305	27	syndromes	syndrome	NNS
cord-320092-0qnvydux	305	28	:	:	:
cord-320092-0qnvydux	305	29	the	the	DT
cord-320092-0qnvydux	305	30	role	role	NN
cord-320092-0qnvydux	305	31	of	of	IN
cord-320092-0qnvydux	305	32	iron	iron	NN
cord-320092-0qnvydux	305	33	depletion	depletion	NN
cord-320092-0qnvydux	305	34	therapy	therapy	NN
cord-320092-0qnvydux	305	35	Palmitoylation	Palmitoylation	NNP
cord-320092-0qnvydux	305	36	of	of	IN
cord-320092-0qnvydux	305	37	the	the	DT
cord-320092-0qnvydux	305	38	cysteine	cysteine	NN
cord-320092-0qnvydux	305	39	-	-	HYPH
cord-320092-0qnvydux	305	40	rich	rich	JJ
cord-320092-0qnvydux	305	41	endodomain	endodomain	NN
cord-320092-0qnvydux	305	42	of	of	IN
cord-320092-0qnvydux	305	43	the	the	DT
cord-320092-0qnvydux	305	44	SARS	SARS	NNP
cord-320092-0qnvydux	305	45	-	-	HYPH
cord-320092-0qnvydux	305	46	coronavirus	coronavirus	NN
cord-320092-0qnvydux	305	47	spike	spike	NN
cord-320092-0qnvydux	305	48	glycoprotein	glycoprotein	NN
cord-320092-0qnvydux	305	49	is	be	VBZ
cord-320092-0qnvydux	305	50	important	important	JJ
cord-320092-0qnvydux	305	51	for	for	IN
cord-320092-0qnvydux	305	52	spike	spike	NN
cord-320092-0qnvydux	305	53	-	-	HYPH
cord-320092-0qnvydux	305	54	mediated	mediate	VBN
cord-320092-0qnvydux	305	55	cell	cell	NN
cord-320092-0qnvydux	305	56	fusion	fusion	NN
cord-320092-0qnvydux	305	57	Genetic	genetic	JJ
cord-320092-0qnvydux	305	58	analysis	analysis	NN
cord-320092-0qnvydux	305	59	of	of	IN
cord-320092-0qnvydux	305	60	the	the	DT
cord-320092-0qnvydux	305	61	SARS	SARS	NNP
cord-320092-0qnvydux	305	62	-	-	HYPH
cord-320092-0qnvydux	305	63	coronavirus	coronavirus	NN
cord-320092-0qnvydux	305	64	spike	spike	NN
cord-320092-0qnvydux	305	65	glycoprotein	glycoprotein	NN
cord-320092-0qnvydux	305	66	functional	functional	JJ
cord-320092-0qnvydux	305	67	domains	domain	NNS
cord-320092-0qnvydux	305	68	involved	involve	VBN
cord-320092-0qnvydux	305	69	in	in	IN
cord-320092-0qnvydux	305	70	cell	cell	NN
cord-320092-0qnvydux	305	71	-	-	HYPH
cord-320092-0qnvydux	305	72	surface	surface	NN
cord-320092-0qnvydux	305	73	expression	expression	NN
cord-320092-0qnvydux	305	74	and	and	CC
cord-320092-0qnvydux	305	75	cell	cell	NN
cord-320092-0qnvydux	305	76	-	-	HYPH
cord-320092-0qnvydux	305	77	to	to	IN
cord-320092-0qnvydux	305	78	-	-	HYPH
cord-320092-0qnvydux	305	79	cell	cell	NN
cord-320092-0qnvydux	305	80	fusion	fusion	NN
cord-320092-0qnvydux	305	81	A	a	DT
cord-320092-0qnvydux	305	82	new	new	JJ
cord-320092-0qnvydux	305	83	mouse	mouse	NN
cord-320092-0qnvydux	305	84	liver	liver	NN
cord-320092-0qnvydux	305	85	-	-	HYPH
cord-320092-0qnvydux	305	86	specific	specific	JJ
cord-320092-0qnvydux	305	87	gene	gene	NN
cord-320092-0qnvydux	305	88	,	,	,
cord-320092-0qnvydux	305	89	encoding	encode	VBG
cord-320092-0qnvydux	305	90	a	a	DT
cord-320092-0qnvydux	305	91	protein	protein	NN
cord-320092-0qnvydux	305	92	homologous	homologous	JJ
cord-320092-0qnvydux	305	93	to	to	IN
cord-320092-0qnvydux	305	94	human	human	JJ
cord-320092-0qnvydux	305	95	antimicrobial	antimicrobial	JJ
cord-320092-0qnvydux	305	96	peptide	peptide	NN
cord-320092-0qnvydux	305	97	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	305	98	,	,	,
cord-320092-0qnvydux	305	99	is	be	VBZ
cord-320092-0qnvydux	305	100	overexpressed	overexpresse	VBN
cord-320092-0qnvydux	305	101	during	during	IN
cord-320092-0qnvydux	305	102	iron	iron	NN
cord-320092-0qnvydux	305	103	overload	overload	NN
cord-320092-0qnvydux	305	104	Hepatic	hepatic	JJ
cord-320092-0qnvydux	305	105	heparan	heparan	NN
cord-320092-0qnvydux	305	106	sulfate	sulfate	NN
cord-320092-0qnvydux	305	107	is	be	VBZ
cord-320092-0qnvydux	305	108	a	a	DT
cord-320092-0qnvydux	305	109	master	master	NN
cord-320092-0qnvydux	305	110	regulator	regulator	NN
cord-320092-0qnvydux	305	111	of	of	IN
cord-320092-0qnvydux	305	112	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	305	113	expression	expression	NN
cord-320092-0qnvydux	305	114	and	and	CC
cord-320092-0qnvydux	305	115	iron	iron	NN
cord-320092-0qnvydux	305	116	homeostasis	homeostasis	NN
cord-320092-0qnvydux	305	117	in	in	IN
cord-320092-0qnvydux	305	118	human	human	JJ
cord-320092-0qnvydux	305	119	hepatocytes	hepatocyte	NNS
cord-320092-0qnvydux	305	120	and	and	CC
cord-320092-0qnvydux	305	121	mice	mouse	NNS
cord-320092-0qnvydux	305	122	Heparin	Heparin	NNP
cord-320092-0qnvydux	305	123	:	:	:
cord-320092-0qnvydux	306	1	a	a	DT
cord-320092-0qnvydux	306	2	potent	potent	JJ
cord-320092-0qnvydux	306	3	inhibitor	inhibitor	NN
cord-320092-0qnvydux	306	4	of	of	IN
cord-320092-0qnvydux	306	5	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	306	6	expression	expression	NN
cord-320092-0qnvydux	306	7	in	in	IN
cord-320092-0qnvydux	306	8	vitro	vitro	FW
cord-320092-0qnvydux	306	9	and	and	CC
cord-320092-0qnvydux	306	10	in	in	IN
cord-320092-0qnvydux	306	11	vivo	vivo	NNP
cord-320092-0qnvydux	306	12	Clinical	clinical	JJ
cord-320092-0qnvydux	306	13	implications	implication	NNS
cord-320092-0qnvydux	306	14	of	of	IN
cord-320092-0qnvydux	306	15	new	new	JJ
cord-320092-0qnvydux	306	16	insights	insight	NNS
cord-320092-0qnvydux	306	17	into	into	IN
cord-320092-0qnvydux	306	18	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	306	19	-	-	HYPH
cord-320092-0qnvydux	306	20	mediated	mediate	VBN
cord-320092-0qnvydux	306	21	regulation	regulation	NN
cord-320092-0qnvydux	306	22	of	of	IN
cord-320092-0qnvydux	306	23	iron	iron	NN
cord-320092-0qnvydux	306	24	absorption	absorption	NN
cord-320092-0qnvydux	306	25	and	and	CC
cord-320092-0qnvydux	306	26	metabolism	metabolism	NN
cord-320092-0qnvydux	306	27	Minihepcidins	minihepcidin	NNS
cord-320092-0qnvydux	306	28	are	be	VBP
cord-320092-0qnvydux	306	29	rationally	rationally	RB
cord-320092-0qnvydux	306	30	designed	design	VBN
cord-320092-0qnvydux	306	31	small	small	JJ
cord-320092-0qnvydux	306	32	peptides	peptide	NNS
cord-320092-0qnvydux	306	33	that	that	WDT
cord-320092-0qnvydux	306	34	mimic	mimic	VBP
cord-320092-0qnvydux	306	35	hepcidin	hepcidin	NN
cord-320092-0qnvydux	306	36	activity	activity	NN
cord-320092-0qnvydux	306	37	in	in	IN
cord-320092-0qnvydux	306	38	mice	mouse	NNS
cord-320092-0qnvydux	306	39	and	and	CC
cord-320092-0qnvydux	306	40	may	may	MD
cord-320092-0qnvydux	306	41	be	be	VB
cord-320092-0qnvydux	306	42	useful	useful	JJ
cord-320092-0qnvydux	306	43	for	for	IN
cord-320092-0qnvydux	306	44	the	the	DT
cord-320092-0qnvydux	306	45	treatment	treatment	NN
cord-320092-0qnvydux	306	46	of	of	IN
cord-320092-0qnvydux	306	47	iron	iron	NN
cord-320092-0qnvydux	306	48	overload	overload	NN
cord-320092-0qnvydux	307	1	The	the	DT
cord-320092-0qnvydux	307	2	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	307	3	/	/	SYM
cord-320092-0qnvydux	307	4	Ferroportin	Ferroportin	NNP
cord-320092-0qnvydux	307	5	axis	axis	NN
cord-320092-0qnvydux	307	6	modulates	modulate	VBZ
cord-320092-0qnvydux	307	7	proliferation	proliferation	NN
cord-320092-0qnvydux	307	8	of	of	IN
cord-320092-0qnvydux	307	9	pulmonary	pulmonary	JJ
cord-320092-0qnvydux	307	10	artery	artery	NN
cord-320092-0qnvydux	307	11	smooth	smooth	JJ
cord-320092-0qnvydux	307	12	muscle	muscle	NN
cord-320092-0qnvydux	307	13	cells	cell	NNS
cord-320092-0qnvydux	307	14	Structure	structure	NN
cord-320092-0qnvydux	307	15	and	and	CC
cord-320092-0qnvydux	307	16	mechanism	mechanism	NN
cord-320092-0qnvydux	307	17	of	of	IN
cord-320092-0qnvydux	307	18	a	a	DT
cord-320092-0qnvydux	307	19	primate	primate	JJ
cord-320092-0qnvydux	307	20	ferroportin	ferroportin	NN
cord-320092-0qnvydux	307	21	Evidence	evidence	NN
cord-320092-0qnvydux	307	22	for	for	IN
cord-320092-0qnvydux	307	23	dimerization	dimerization	NN
cord-320092-0qnvydux	307	24	of	of	IN
cord-320092-0qnvydux	307	25	ferroportin	ferroportin	NN
cord-320092-0qnvydux	307	26	in	in	IN
cord-320092-0qnvydux	307	27	a	a	DT
cord-320092-0qnvydux	307	28	human	human	JJ
cord-320092-0qnvydux	307	29	hepatic	hepatic	JJ
cord-320092-0qnvydux	307	30	cell	cell	NN
cord-320092-0qnvydux	307	31	line	line	NN
cord-320092-0qnvydux	307	32	using	use	VBG
cord-320092-0qnvydux	307	33	proximity	proximity	NN
cord-320092-0qnvydux	307	34	ligation	ligation	NN
cord-320092-0qnvydux	307	35	assays	assay	NNS
cord-320092-0qnvydux	308	1	A	a	DT
cord-320092-0qnvydux	308	2	hypothesized	hypothesize	VBN
cord-320092-0qnvydux	308	3	role	role	NN
cord-320092-0qnvydux	308	4	for	for	IN
cord-320092-0qnvydux	308	5	dysregulated	dysregulated	JJ
cord-320092-0qnvydux	308	6	bradykinin	bradykinin	NN
cord-320092-0qnvydux	308	7	signaling	signal	VBG
cord-320092-0qnvydux	308	8	in	in	IN
cord-320092-0qnvydux	308	9	COVID-19	covid-19	JJ
cord-320092-0qnvydux	308	10	respiratory	respiratory	JJ
cord-320092-0qnvydux	308	11	complications	complication	NNS
cord-320092-0qnvydux	308	12	Evolutionary	evolutionary	JJ
cord-320092-0qnvydux	308	13	descent	descent	NN
cord-320092-0qnvydux	308	14	of	of	IN
cord-320092-0qnvydux	308	15	prion	prion	NN
cord-320092-0qnvydux	308	16	genes	gene	NNS
cord-320092-0qnvydux	308	17	from	from	IN
cord-320092-0qnvydux	308	18	the	the	DT
cord-320092-0qnvydux	308	19	ZIP	ZIP	NNP
cord-320092-0qnvydux	308	20	family	family	NN
cord-320092-0qnvydux	308	21	of	of	IN
cord-320092-0qnvydux	308	22	metal	metal	NN
cord-320092-0qnvydux	308	23	ion	ion	NN
cord-320092-0qnvydux	308	24	transporters	transporter	NNS
cord-320092-0qnvydux	308	25	Coronavirus	Coronavirus	NNP
cord-320092-0qnvydux	308	26	envelope	envelope	NN
cord-320092-0qnvydux	308	27	protein	protein	NN
cord-320092-0qnvydux	308	28	:	:	:
cord-320092-0qnvydux	308	29	current	current	JJ
cord-320092-0qnvydux	308	30	knowledge	knowledge	NN
cord-320092-0qnvydux	308	31	Revisiting	revisit	VBG
cord-320092-0qnvydux	308	32	the	the	DT
cord-320092-0qnvydux	308	33	dangers	danger	NNS
cord-320092-0qnvydux	308	34	of	of	IN
cord-320092-0qnvydux	308	35	the	the	DT
cord-320092-0qnvydux	308	36	coronavirus	coronavirus	NN
cord-320092-0qnvydux	308	37	in	in	IN
cord-320092-0qnvydux	308	38	the	the	DT
cord-320092-0qnvydux	308	39	ophthalmology	ophthalmology	NN
cord-320092-0qnvydux	308	40	practice	practice	NN
cord-320092-0qnvydux	308	41	Systemic	systemic	JJ
cord-320092-0qnvydux	308	42	hypoferremia	hypoferremia	NN
cord-320092-0qnvydux	308	43	and	and	CC
cord-320092-0qnvydux	308	44	severity	severity	NN
cord-320092-0qnvydux	308	45	of	of	IN
cord-320092-0qnvydux	308	46	hypoxemic	hypoxemic	JJ
cord-320092-0qnvydux	308	47	respiratory	respiratory	JJ
cord-320092-0qnvydux	308	48	failure	failure	NN
cord-320092-0qnvydux	308	49	in	in	IN
cord-320092-0qnvydux	308	50	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	308	51	Structure	Structure	NNP
cord-320092-0qnvydux	308	52	of	of	IN
cord-320092-0qnvydux	308	53	mouse	mouse	NN
cord-320092-0qnvydux	308	54	coronavirus	coronavirus	NN
cord-320092-0qnvydux	308	55	spike	spike	NN
cord-320092-0qnvydux	308	56	protein	protein	NN
cord-320092-0qnvydux	308	57	complexed	complexe	VBN
cord-320092-0qnvydux	308	58	with	with	IN
cord-320092-0qnvydux	308	59	receptor	receptor	NN
cord-320092-0qnvydux	309	1	reveals	reveal	VBZ
cord-320092-0qnvydux	309	2	mechanism	mechanism	NN
cord-320092-0qnvydux	309	3	for	for	IN
cord-320092-0qnvydux	309	4	viral	viral	JJ
cord-320092-0qnvydux	309	5	entry	entry	NN
cord-320092-0qnvydux	309	6	COVID-19	covid-19	CD
cord-320092-0qnvydux	309	7	infection	infection	NN
cord-320092-0qnvydux	309	8	:	:	:
cord-320092-0qnvydux	310	1	the	the	DT
cord-320092-0qnvydux	310	2	perspectives	perspective	NNS
cord-320092-0qnvydux	310	3	on	on	IN
cord-320092-0qnvydux	310	4	immune	immune	JJ
cord-320092-0qnvydux	310	5	responses	response	NNS
cord-320092-0qnvydux	310	6	Role	role	NN
cord-320092-0qnvydux	310	7	of	of	IN
cord-320092-0qnvydux	310	8	spike	spike	NN
cord-320092-0qnvydux	310	9	protein	protein	NN
cord-320092-0qnvydux	310	10	endodomains	endodomain	NNS
cord-320092-0qnvydux	310	11	in	in	IN
cord-320092-0qnvydux	310	12	regulating	regulate	VBG
cord-320092-0qnvydux	310	13	coronavirus	coronavirus	NN
cord-320092-0qnvydux	310	14	entry	entry	NN
cord-320092-0qnvydux	310	15	Protein	Protein	NNP
cord-320092-0qnvydux	310	16	Palmitoylation	Palmitoylation	NNP
cord-320092-0qnvydux	310	17	and	and	CC
cord-320092-0qnvydux	310	18	its	-PRON-	PRP$
cord-320092-0qnvydux	310	19	role	role	NN
cord-320092-0qnvydux	310	20	in	in	IN
cord-320092-0qnvydux	310	21	bacterial	bacterial	JJ
cord-320092-0qnvydux	310	22	and	and	CC
cord-320092-0qnvydux	310	23	viral	viral	JJ
cord-320092-0qnvydux	310	24	infections	infection	NNS
cord-320092-0qnvydux	310	25	Controversies	controversy	NNS
cord-320092-0qnvydux	310	26	of	of	IN
cord-320092-0qnvydux	310	27	renin	renin	NN
cord-320092-0qnvydux	310	28	-	-	HYPH
cord-320092-0qnvydux	310	29	angiotensin	angiotensin	NN
cord-320092-0qnvydux	310	30	system	system	NN
cord-320092-0qnvydux	310	31	inhibition	inhibition	NN
cord-320092-0qnvydux	310	32	during	during	IN
cord-320092-0qnvydux	310	33	the	the	DT
cord-320092-0qnvydux	310	34	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	310	35	pandemic	pandemic	NN
cord-320092-0qnvydux	310	36	Anticoagulant	anticoagulant	JJ
cord-320092-0qnvydux	310	37	treatment	treatment	NN
cord-320092-0qnvydux	310	38	is	be	VBZ
cord-320092-0qnvydux	310	39	associated	associate	VBN
cord-320092-0qnvydux	310	40	with	with	IN
cord-320092-0qnvydux	310	41	decreased	decrease	VBN
cord-320092-0qnvydux	310	42	mortality	mortality	NN
cord-320092-0qnvydux	310	43	in	in	IN
cord-320092-0qnvydux	310	44	severe	severe	JJ
cord-320092-0qnvydux	310	45	coronavirus	coronavirus	NN
cord-320092-0qnvydux	310	46	disease	disease	NN
cord-320092-0qnvydux	310	47	2019	2019	CD
cord-320092-0qnvydux	310	48	patients	patient	NNS
cord-320092-0qnvydux	310	49	with	with	IN
cord-320092-0qnvydux	310	50	coagulopathy	coagulopathy	NN
cord-320092-0qnvydux	310	51	Coronavirus	Coronavirus	NNP
cord-320092-0qnvydux	310	52	membrane	membrane	NN
cord-320092-0qnvydux	310	53	fusion	fusion	NN
cord-320092-0qnvydux	310	54	mechanism	mechanism	NN
cord-320092-0qnvydux	310	55	offers	offer	VBZ
cord-320092-0qnvydux	310	56	a	a	DT
cord-320092-0qnvydux	310	57	potential	potential	JJ
cord-320092-0qnvydux	310	58	target	target	NN
cord-320092-0qnvydux	310	59	for	for	IN
cord-320092-0qnvydux	310	60	antiviral	antiviral	JJ
cord-320092-0qnvydux	310	61	development	development	NN
cord-320092-0qnvydux	311	1	Transferrin	Transferrin	NNP
cord-320092-0qnvydux	311	2	plays	play	VBZ
cord-320092-0qnvydux	311	3	a	a	DT
cord-320092-0qnvydux	311	4	central	central	JJ
cord-320092-0qnvydux	311	5	role	role	NN
cord-320092-0qnvydux	311	6	in	in	IN
cord-320092-0qnvydux	311	7	coagulation	coagulation	NN
cord-320092-0qnvydux	311	8	balance	balance	NN
cord-320092-0qnvydux	311	9	by	by	IN
cord-320092-0qnvydux	311	10	interacting	interact	VBG
cord-320092-0qnvydux	311	11	with	with	IN
cord-320092-0qnvydux	311	12	clotting	clotting	NN
cord-320092-0qnvydux	311	13	factors	factor	NNS
cord-320092-0qnvydux	311	14	From	from	IN
cord-320092-0qnvydux	311	15	yeast	yeast	NN
cord-320092-0qnvydux	311	16	to	to	IN
cord-320092-0qnvydux	311	17	patient	patient	JJ
cord-320092-0qnvydux	311	18	neurons	neuron	NNS
cord-320092-0qnvydux	311	19	and	and	CC
cord-320092-0qnvydux	311	20	back	back	RB
cord-320092-0qnvydux	311	21	again	again	RB
cord-320092-0qnvydux	311	22	:	:	:
cord-320092-0qnvydux	312	1	powerful	powerful	JJ
cord-320092-0qnvydux	312	2	new	new	JJ
cord-320092-0qnvydux	312	3	discovery	discovery	NN
cord-320092-0qnvydux	312	4	platform	platform	NN
cord-320092-0qnvydux	312	5	Posttranslational	Posttranslational	NNP
cord-320092-0qnvydux	312	6	processing	processing	NN
cord-320092-0qnvydux	312	7	of	of	IN
cord-320092-0qnvydux	312	8	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	312	9	in	in	IN
cord-320092-0qnvydux	312	10	human	human	JJ
cord-320092-0qnvydux	312	11	hepatocytes	hepatocyte	NNS
cord-320092-0qnvydux	312	12	is	be	VBZ
cord-320092-0qnvydux	312	13	mediated	mediate	VBN
cord-320092-0qnvydux	312	14	by	by	IN
cord-320092-0qnvydux	312	15	the	the	DT
cord-320092-0qnvydux	312	16	prohormone	prohormone	NN
cord-320092-0qnvydux	312	17	convertase	convertase	NN
cord-320092-0qnvydux	312	18	furin	furin	NN
cord-320092-0qnvydux	312	19	Tetraodon	Tetraodon	NNP
cord-320092-0qnvydux	312	20	genome	genome	NN
cord-320092-0qnvydux	312	21	confirms	confirm	VBZ
cord-320092-0qnvydux	312	22	Takifugu	Takifugu	NNP
cord-320092-0qnvydux	312	23	findings	finding	NNS
cord-320092-0qnvydux	312	24	:	:	:
cord-320092-0qnvydux	312	25	most	most	JJS
cord-320092-0qnvydux	312	26	fish	fish	NN
cord-320092-0qnvydux	312	27	are	be	VBP
cord-320092-0qnvydux	312	28	ancient	ancient	JJ
cord-320092-0qnvydux	312	29	polyploids	polyploid	NNS
cord-320092-0qnvydux	313	1	The	the	DT
cord-320092-0qnvydux	313	2	multifaceted	multifaceted	JJ
cord-320092-0qnvydux	313	3	role	role	NN
cord-320092-0qnvydux	313	4	of	of	IN
cord-320092-0qnvydux	313	5	iron	iron	NN
cord-320092-0qnvydux	313	6	in	in	IN
cord-320092-0qnvydux	313	7	renal	renal	JJ
cord-320092-0qnvydux	313	8	health	health	NN
cord-320092-0qnvydux	313	9	and	and	CC
cord-320092-0qnvydux	313	10	disease	disease	NN
cord-320092-0qnvydux	314	1	An	an	DT
cord-320092-0qnvydux	314	2	outbreak	outbreak	NN
cord-320092-0qnvydux	314	3	of	of	IN
cord-320092-0qnvydux	314	4	severe	severe	JJ
cord-320092-0qnvydux	314	5	Kawasaki	Kawasaki	NNP
cord-320092-0qnvydux	314	6	-	-	HYPH
cord-320092-0qnvydux	314	7	like	like	JJ
cord-320092-0qnvydux	314	8	disease	disease	NN
cord-320092-0qnvydux	314	9	at	at	IN
cord-320092-0qnvydux	314	10	the	the	DT
cord-320092-0qnvydux	314	11	Italian	italian	JJ
cord-320092-0qnvydux	314	12	epicentre	epicentre	NN
cord-320092-0qnvydux	314	13	of	of	IN
cord-320092-0qnvydux	314	14	the	the	DT
cord-320092-0qnvydux	314	15	SARS	SARS	NNP
cord-320092-0qnvydux	314	16	-	-	HYPH
cord-320092-0qnvydux	314	17	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	314	18	epidemic	epidemic	NN
cord-320092-0qnvydux	314	19	:	:	:
cord-320092-0qnvydux	315	1	an	an	DT
cord-320092-0qnvydux	315	2	observational	observational	JJ
cord-320092-0qnvydux	315	3	cohort	cohort	NN
cord-320092-0qnvydux	315	4	study	study	NN
cord-320092-0qnvydux	315	5	Acylation	Acylation	NNP
cord-320092-0qnvydux	315	6	-	-	HYPH
cord-320092-0qnvydux	315	7	mediated	mediate	VBN
cord-320092-0qnvydux	315	8	membrane	membrane	NN
cord-320092-0qnvydux	315	9	anchoring	anchoring	NN
cord-320092-0qnvydux	315	10	of	of	IN
cord-320092-0qnvydux	315	11	avian	avian	JJ
cord-320092-0qnvydux	315	12	influenza	influenza	NN
cord-320092-0qnvydux	315	13	virus	virus	NN
cord-320092-0qnvydux	315	14	hemagglutinin	hemagglutinin	NNP
cord-320092-0qnvydux	315	15	is	be	VBZ
cord-320092-0qnvydux	315	16	essential	essential	JJ
cord-320092-0qnvydux	315	17	for	for	IN
cord-320092-0qnvydux	315	18	fusion	fusion	NN
cord-320092-0qnvydux	315	19	pore	pore	NN
cord-320092-0qnvydux	315	20	formation	formation	NN
cord-320092-0qnvydux	315	21	and	and	CC
cord-320092-0qnvydux	315	22	virus	virus	NN
cord-320092-0qnvydux	315	23	infectivity	infectivity	NN
cord-320092-0qnvydux	315	24	Structure	Structure	NNP
cord-320092-0qnvydux	315	25	,	,	,
cord-320092-0qnvydux	315	26	function	function	NN
cord-320092-0qnvydux	315	27	,	,	,
cord-320092-0qnvydux	315	28	and	and	CC
cord-320092-0qnvydux	315	29	antigenicity	antigenicity	NN
cord-320092-0qnvydux	315	30	of	of	IN
cord-320092-0qnvydux	315	31	the	the	DT
cord-320092-0qnvydux	315	32	SARS	SARS	NNP
cord-320092-0qnvydux	315	33	-	-	HYPH
cord-320092-0qnvydux	315	34	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	315	35	spike	spike	NN
cord-320092-0qnvydux	315	36	glycoprotein	glycoprotein	NN
cord-320092-0qnvydux	315	37	Association	Association	NNP
cord-320092-0qnvydux	315	38	between	between	IN
cord-320092-0qnvydux	315	39	Administration	Administration	NNP
cord-320092-0qnvydux	315	40	of	of	IN
cord-320092-0qnvydux	315	41	Systemic	Systemic	NNP
cord-320092-0qnvydux	315	42	Corticosteroids	Corticosteroids	NNPS
cord-320092-0qnvydux	315	43	and	and	CC
cord-320092-0qnvydux	315	44	Mortality	mortality	NN
cord-320092-0qnvydux	315	45	among	among	IN
cord-320092-0qnvydux	315	46	Critically	critically	RB
cord-320092-0qnvydux	315	47	ill	ill	JJ
cord-320092-0qnvydux	315	48	Patients	patient	NNS
cord-320092-0qnvydux	315	49	with	with	IN
cord-320092-0qnvydux	315	50	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	315	51	:	:	:
cord-320092-0qnvydux	315	52	a	a	DT
cord-320092-0qnvydux	315	53	meta	meta	JJ
cord-320092-0qnvydux	315	54	-	-	HYPH
cord-320092-0qnvydux	315	55	analysis	analysis	NN
cord-320092-0qnvydux	316	1	The	the	DT
cord-320092-0qnvydux	316	2	3.1-angstrom	3.1-angstrom	CD
cord-320092-0qnvydux	316	3	Cryo	cryo	NN
cord-320092-0qnvydux	316	4	-	-	HYPH
cord-320092-0qnvydux	316	5	electron	electron	NN
cord-320092-0qnvydux	316	6	microscopy	microscopy	NN
cord-320092-0qnvydux	316	7	structure	structure	NN
cord-320092-0qnvydux	316	8	of	of	IN
cord-320092-0qnvydux	316	9	the	the	DT
cord-320092-0qnvydux	316	10	porcine	porcine	JJ
cord-320092-0qnvydux	316	11	epidemic	epidemic	NN
cord-320092-0qnvydux	316	12	diarrhea	diarrhea	NN
cord-320092-0qnvydux	316	13	virus	virus	NN
cord-320092-0qnvydux	316	14	spike	spike	NN
cord-320092-0qnvydux	316	15	protein	protein	NN
cord-320092-0qnvydux	316	16	in	in	IN
cord-320092-0qnvydux	316	17	the	the	DT
cord-320092-0qnvydux	316	18	Prefusion	Prefusion	NNP
cord-320092-0qnvydux	316	19	conformation	conformation	NN
cord-320092-0qnvydux	316	20	Cryo	Cryo	NNP
cord-320092-0qnvydux	316	21	-	-	HYPH
cord-320092-0qnvydux	316	22	EM	EM	NNP
cord-320092-0qnvydux	316	23	structure	structure	NN
cord-320092-0qnvydux	316	24	of	of	IN
cord-320092-0qnvydux	316	25	the	the	DT
cord-320092-0qnvydux	316	26	2019-nCoV	2019-ncov	CD
cord-320092-0qnvydux	316	27	spike	spike	NN
cord-320092-0qnvydux	316	28	in	in	IN
cord-320092-0qnvydux	316	29	the	the	DT
cord-320092-0qnvydux	316	30	prefusion	prefusion	NN
cord-320092-0qnvydux	316	31	conformation	conformation	NN
cord-320092-0qnvydux	316	32	Genome	Genome	NNP
cord-320092-0qnvydux	316	33	composition	composition	NN
cord-320092-0qnvydux	316	34	and	and	CC
cord-320092-0qnvydux	316	35	divergence	divergence	NN
cord-320092-0qnvydux	316	36	of	of	IN
cord-320092-0qnvydux	316	37	the	the	DT
cord-320092-0qnvydux	316	38	novel	novel	JJ
cord-320092-0qnvydux	316	39	coronavirus	coronavirus	NN
cord-320092-0qnvydux	316	40	(	(	-LRB-
cord-320092-0qnvydux	316	41	2019-nCoV	2019-ncov	CD
cord-320092-0qnvydux	316	42	)	)	-RRB-
cord-320092-0qnvydux	316	43	originating	originate	VBG
cord-320092-0qnvydux	316	44	in	in	IN
cord-320092-0qnvydux	316	45	China	China	NNP
cord-320092-0qnvydux	317	1	A	a	DT
cord-320092-0qnvydux	317	2	new	new	JJ
cord-320092-0qnvydux	317	3	coronavirus	coronavirus	NN
cord-320092-0qnvydux	317	4	associated	associate	VBN
cord-320092-0qnvydux	317	5	with	with	IN
cord-320092-0qnvydux	317	6	human	human	JJ
cord-320092-0qnvydux	317	7	respiratory	respiratory	JJ
cord-320092-0qnvydux	317	8	disease	disease	NN
cord-320092-0qnvydux	317	9	in	in	IN
cord-320092-0qnvydux	317	10	China	China	NNP
cord-320092-0qnvydux	318	1	The	the	DT
cord-320092-0qnvydux	318	2	E	e	NN
cord-320092-0qnvydux	318	3	protein	protein	NN
cord-320092-0qnvydux	318	4	is	be	VBZ
cord-320092-0qnvydux	318	5	a	a	DT
cord-320092-0qnvydux	318	6	multifunctional	multifunctional	JJ
cord-320092-0qnvydux	318	7	membrane	membrane	NN
cord-320092-0qnvydux	318	8	protein	protein	NN
cord-320092-0qnvydux	318	9	of	of	IN
cord-320092-0qnvydux	318	10	SARS	SARS	NNP
cord-320092-0qnvydux	318	11	-	-	HYPH
cord-320092-0qnvydux	318	12	CoV	CoV	NNP
cord-320092-0qnvydux	318	13	Fusion	Fusion	NNP
cord-320092-0qnvydux	318	14	mechanism	mechanism	NN
cord-320092-0qnvydux	318	15	of	of	IN
cord-320092-0qnvydux	318	16	2019-nCoV	2019-ncov	CD
cord-320092-0qnvydux	318	17	and	and	CC
cord-320092-0qnvydux	318	18	fusion	fusion	NN
cord-320092-0qnvydux	318	19	inhibitors	inhibitor	NNS
cord-320092-0qnvydux	318	20	targeting	target	VBG
cord-320092-0qnvydux	318	21	HR1	HR1	NNP
cord-320092-0qnvydux	318	22	domain	domain	NN
cord-320092-0qnvydux	318	23	in	in	IN
cord-320092-0qnvydux	318	24	spike	spike	NN
cord-320092-0qnvydux	318	25	protein	protein	NN
cord-320092-0qnvydux	318	26	Adaptive	adaptive	JJ
cord-320092-0qnvydux	318	27	evolution	evolution	NN
cord-320092-0qnvydux	318	28	of	of	IN
cord-320092-0qnvydux	318	29	hepcidin	hepcidin	NNP
cord-320092-0qnvydux	318	30	genes	gene	NNS
cord-320092-0qnvydux	318	31	in	in	IN
cord-320092-0qnvydux	318	32	antarctic	antarctic	NNP
cord-320092-0qnvydux	318	33	notothenioid	notothenioid	NNP
cord-320092-0qnvydux	318	34	fishes	fish	VBZ
cord-320092-0qnvydux	319	1	Effective	effective	JJ
cord-320092-0qnvydux	319	2	treatment	treatment	NN
cord-320092-0qnvydux	319	3	of	of	IN
cord-320092-0qnvydux	319	4	severe	severe	JJ
cord-320092-0qnvydux	319	5	COVID-19	covid-19	JJ
cord-320092-0qnvydux	319	6	patients	patient	NNS
cord-320092-0qnvydux	319	7	with	with	IN
cord-320092-0qnvydux	319	8	tocilizumab	tocilizumab	NNP
cord-320092-0qnvydux	319	9	Molecular	Molecular	NNP
cord-320092-0qnvydux	319	10	cloning	clone	VBG
cord-320092-0qnvydux	319	11	of	of	IN
cord-320092-0qnvydux	319	12	a	a	DT
cord-320092-0qnvydux	319	13	lipolysis	lipolysis	NN
cord-320092-0qnvydux	319	14	-	-	HYPH
cord-320092-0qnvydux	319	15	stimulated	stimulate	VBN
cord-320092-0qnvydux	319	16	remnant	remnant	JJ
cord-320092-0qnvydux	319	17	receptor	receptor	NN
cord-320092-0qnvydux	319	18	expressed	express	VBN
cord-320092-0qnvydux	319	19	in	in	IN
cord-320092-0qnvydux	319	20	the	the	DT
cord-320092-0qnvydux	319	21	liver	liver	NN
cord-320092-0qnvydux	319	22	TMPRSS2	TMPRSS2	NNP
cord-320092-0qnvydux	319	23	and	and	CC
cord-320092-0qnvydux	320	1	TMPRSS4	TMPRSS4	NNS
cord-320092-0qnvydux	320	2	promote	promote	VBP
cord-320092-0qnvydux	320	3	SARS	SARS	NNP
cord-320092-0qnvydux	320	4	-	-	HYPH
cord-320092-0qnvydux	320	5	CoV-2	CoV-2	NNP
cord-320092-0qnvydux	320	6	infection	infection	NN
cord-320092-0qnvydux	320	7	of	of	IN
cord-320092-0qnvydux	320	8	human	human	JJ
cord-320092-0qnvydux	320	9	small	small	JJ
cord-320092-0qnvydux	320	10	intestinal	intestinal	JJ
cord-320092-0qnvydux	320	11	enterocytes	enterocyte	NNS
cord-320092-0qnvydux	320	12	Potential	potential	JJ
cord-320092-0qnvydux	320	13	interventions	intervention	NNS
cord-320092-0qnvydux	320	14	for	for	IN
cord-320092-0qnvydux	320	15	novel	novel	JJ
cord-320092-0qnvydux	320	16	coronavirus	coronavirus	NN
cord-320092-0qnvydux	320	17	in	in	IN
cord-320092-0qnvydux	320	18	China	China	NNP
cord-320092-0qnvydux	320	19	:	:	:
cord-320092-0qnvydux	321	1	a	a	DT
cord-320092-0qnvydux	321	2	systematic	systematic	JJ
cord-320092-0qnvydux	321	3	review	review	NN
cord-320092-0qnvydux	321	4	Serum	serum	NN
cord-320092-0qnvydux	321	5	iron	iron	NN
cord-320092-0qnvydux	321	6	level	level	NN
cord-320092-0qnvydux	321	7	as	as	IN
cord-320092-0qnvydux	321	8	a	a	DT
cord-320092-0qnvydux	321	9	potential	potential	JJ
cord-320092-0qnvydux	321	10	predictor	predictor	NN
cord-320092-0qnvydux	321	11	of	of	IN
cord-320092-0qnvydux	321	12	coronavirus	coronavirus	NN
cord-320092-0qnvydux	321	13	disease	disease	NN
cord-320092-0qnvydux	321	14	2019	2019	CD
cord-320092-0qnvydux	321	15	severity	severity	NN
cord-320092-0qnvydux	321	16	and	and	CC
cord-320092-0qnvydux	321	17	mortality	mortality	NN
cord-320092-0qnvydux	321	18	:	:	:
cord-320092-0qnvydux	322	1	a	a	DT
cord-320092-0qnvydux	322	2	retrospective	retrospective	JJ
cord-320092-0qnvydux	322	3	study	study	NN
cord-320092-0qnvydux	322	4	Increased	increase	VBN
cord-320092-0qnvydux	322	5	serum	serum	NN
cord-320092-0qnvydux	322	6	levels	level	NNS
cord-320092-0qnvydux	322	7	of	of	IN
cord-320092-0qnvydux	322	8	Hepcidin	Hepcidin	NNP
cord-320092-0qnvydux	322	9	and	and	CC
cord-320092-0qnvydux	322	10	ferritin	ferritin	NNS
cord-320092-0qnvydux	322	11	are	be	VBP
cord-320092-0qnvydux	322	12	associated	associate	VBN
cord-320092-0qnvydux	322	13	with	with	IN
cord-320092-0qnvydux	322	14	severity	severity	NN
cord-320092-0qnvydux	322	15	of	of	IN
cord-320092-0qnvydux	322	16	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	322	17	Clinical	clinical	JJ
cord-320092-0qnvydux	322	18	course	course	NN
cord-320092-0qnvydux	322	19	and	and	CC
cord-320092-0qnvydux	322	20	risk	risk	NN
cord-320092-0qnvydux	322	21	factors	factor	NNS
cord-320092-0qnvydux	322	22	for	for	IN
cord-320092-0qnvydux	322	23	mortality	mortality	NN
cord-320092-0qnvydux	322	24	of	of	IN
cord-320092-0qnvydux	322	25	adult	adult	NN
cord-320092-0qnvydux	322	26	inpatients	inpatient	NNS
cord-320092-0qnvydux	322	27	with	with	IN
cord-320092-0qnvydux	322	28	COVID-19	COVID-19	NNP
cord-320092-0qnvydux	322	29	in	in	IN
cord-320092-0qnvydux	322	30	Wuhan	Wuhan	NNP
cord-320092-0qnvydux	322	31	,	,	,
cord-320092-0qnvydux	322	32	China	China	NNP
cord-320092-0qnvydux	322	33	:	:	:
cord-320092-0qnvydux	322	34	a	a	DT
cord-320092-0qnvydux	322	35	retrospective	retrospective	JJ
cord-320092-0qnvydux	322	36	cohort	cohort	NN
cord-320092-0qnvydux	322	37	study	study	NN
cord-320092-0qnvydux	323	1	A	a	DT
cord-320092-0qnvydux	323	2	completely	completely	RB
cord-320092-0qnvydux	323	3	Reimplemented	reimplemente	VBN
cord-320092-0qnvydux	323	4	MPI	MPI	NNP
cord-320092-0qnvydux	323	5	bioinformatics	bioinformatics	NN
cord-320092-0qnvydux	323	6	toolkit	toolkit	NN
cord-320092-0qnvydux	323	7	with	with	IN
cord-320092-0qnvydux	323	8	a	a	DT
cord-320092-0qnvydux	323	9	new	new	JJ
cord-320092-0qnvydux	323	10	HHpred	HHpred	NNP
cord-320092-0qnvydux	323	11	server	server	NN
cord-320092-0qnvydux	323	12	at	at	IN
cord-320092-0qnvydux	323	13	its	-PRON-	PRP$
cord-320092-0qnvydux	323	14	Core	Core	NNP
cord-320092-0qnvydux	323	15	Publisher	Publisher	NNP
cord-320092-0qnvydux	323	16	's	's	POS
cord-320092-0qnvydux	323	17	Note	Note	NNP
cord-320092-0qnvydux	323	18	Springer	Springer	NNP
cord-320092-0qnvydux	323	19	Nature	Nature	NNP
cord-320092-0qnvydux	323	20	remains	remain	VBZ
cord-320092-0qnvydux	323	21	neutral	neutral	JJ
cord-320092-0qnvydux	323	22	with	with	IN
cord-320092-0qnvydux	323	23	regard	regard	NN
cord-320092-0qnvydux	323	24	to	to	IN
cord-320092-0qnvydux	323	25	jurisdictional	jurisdictional	JJ
cord-320092-0qnvydux	323	26	claims	claim	NNS
cord-320092-0qnvydux	323	27	in	in	IN
cord-320092-0qnvydux	323	28	published	publish	VBN
cord-320092-0qnvydux	323	29	maps	map	NNS
cord-320092-0qnvydux	323	30	and	and	CC
cord-320092-0qnvydux	323	31	institutional	institutional	JJ
cord-320092-0qnvydux	323	32	affiliations	affiliation	NNS
cord-320092-0qnvydux	323	33	Ethics	Ethics	NNP
cord-320092-0qnvydux	323	34	approval	approval	NN
cord-320092-0qnvydux	323	35	and	and	CC
cord-320092-0qnvydux	323	36	consent	consent	NN
cord-320092-0qnvydux	323	37	to	to	TO
cord-320092-0qnvydux	323	38	participate	participate	VB
cord-320092-0qnvydux	323	39	Not	not	RB
cord-320092-0qnvydux	323	40	applicable	applicable	JJ
cord-320092-0qnvydux	323	41	.	.	.
cord-320092-0qnvydux	324	1	Not	not	RB
cord-320092-0qnvydux	324	2	applicable	applicable	JJ
cord-320092-0qnvydux	324	3	.	.	.
cord-320092-0qnvydux	325	1	The	the	DT
cord-320092-0qnvydux	325	2	author	author	NN
cord-320092-0qnvydux	325	3	declares	declare	VBZ
cord-320092-0qnvydux	325	4	no	no	DT
cord-320092-0qnvydux	325	5	competing	compete	VBG
cord-320092-0qnvydux	325	6	interests	interest	NNS
cord-320092-0qnvydux	325	7	.	.	.
cord-320092-0qnvydux	326	1	Received	receive	VBN
cord-320092-0qnvydux	326	2	:	:	:
cord-320092-0qnvydux	326	3	3	3	CD
cord-320092-0qnvydux	326	4	July	July	NNP
cord-320092-0qnvydux	326	5	2020	2020	CD
cord-320092-0qnvydux	327	1	Accepted	accept	VBN
cord-320092-0qnvydux	327	2	:	:	:
cord-320092-0qnvydux	327	3	8	8	CD
cord-320092-0qnvydux	327	4	October	October	NNP
cord-320092-0qnvydux	327	5	2020	2020	CD