id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-281676-yy5etfek	Dwivedi, Varun	Cross-protective immunity to porcine reproductive and respiratory syndrome virus by intranasal delivery of a live virus vaccine with a potent adjuvant	2011-05-23		.txt	text/plain	5960	288	46	Consistent with the reduced lung lesions and viremia, a significantly increased frequency of IFN-␥Table 1 Frequency of immune cells in pigs inoculated intranasally with mock (no vaccination and no challenge), unvaccinated (n = 9) or vaccinated with PRRS-MLV+ Mtb WCL (n = 9) and then challenged with PRRSV MN184. Evaluation of the frequency of various immune cells at both mucosal (lung and TBLN MNC) and systemic sites (PBMC) in vaccinated and virulent PRRSV challenged pigs is important for associating cytokine responses. In our study, a consistently reduced frequency of Tregs in the lungs, blood, and TBLN of pigs vaccinated intranasally with PRRS-MLV+ Mtb WCL was detected which was associated with reduced secretion of both the immunosuppressive cytokines, IL-10 and TGF-␤. Intranasal delivery of whole cell lysate of Mycobacterium tuberculosis induces protective immune responses to a modified live porcine reproductive and respiratory syndrome virus vaccine in pigs	./cache/cord-281676-yy5etfek.txt	./txt/cord-281676-yy5etfek.txt