id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-293613-xnos7iud	Ritchie, Andrew I.	Definition, Causes, Pathogenesis, and Consequences of Chronic Obstructive Pulmonary Disease Exacerbations	2020-08-12		.txt	text/plain	7485	393	33	The 2017 Global Initiative for Chronic Obstructive Lung Disease (GOLD) document AECOPD definition slightly differs from this as "an acute worsening of respiratory symptoms that results in additional therapy." This definition requires the patient to seek or use treatment and is an example of a health care use (HCU) exacerbation in which the patient or clinician decides whether treatment is warranted. This approach has been widely accepted in research, using several validated patient-reported outcome (PRO) tools such as symptom/treatment diary cards and questionnaire tools such as the EXACT (Exacerbations of Chronic Obstructive Pulmonary Disease Tool) and CAT (The COPD Assessment Test). Analysis of viral infection and biomarkers in patients with acute exacerbation of chronic obstructive pulmonary disease	./cache/cord-293613-xnos7iud.txt	./txt/cord-293613-xnos7iud.txt