id author title date pages extension mime words sentences flesch summary cache txt cord-320447-nq9f1gmu Lins, Muriel Assessment of small pulmonary blood vessels in COVID-19 patients using HRCT 2020-07-25 .txt text/plain 2811 134 45 Results: Compared to healthy volunteers, COVID-19 patients showed significant reduction in BV5 (pulmonary blood volume contained in blood vessels of <5 mm(2)) expressed as BV5/(Total pulmonary blood volume) (p<0.0001), and significant increases in BV5-10 and BV 10 (pulmonary blood volumes contained in vessels between 5 and 10 mm(2) and above 10 mm(2), respectively) (p<0.0001). Conclusions: COVID-19 patients display striking anomalies in the distribution of blood volume within the pulmonary vascular tree, consistent with increased pulmonary vasculature resistance in the pulmonary vessels below the resolution of CT. These results suggest that while the pathological changes to the pulmonary vasculature implicated in pulmonary vascular disease (PVD), collectively termed "pulmonary vascular remodeling", occur primarily below the resolution of CT scans, those processes do have a measurable effect on larger, more proximal vessels. In this study we assessed the use of novel CT-derived measures of pulmonary blood volume and pulmonary vascular density in patients with COVID-19. ./cache/cord-320447-nq9f1gmu.txt ./txt/cord-320447-nq9f1gmu.txt