id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-322919-5ty35rsy	Busana, Mattia	Non‐invasive hemodynamic profile of early COVID‐19 infection	2020-10-28		.txt	text/plain	2510	174	51	When stratifying for SVRI, patients with an SVRI value below the cohort median had also more severe oxygenation impairment and lower TPR, despite a similar degree of CXR infiltrates. CONCLUSIONS: In the early stages of COVID‐19 infection the hemodynamic profile is characterized by a hyperdynamic circulatory state with high CI and low SVRI, while the right heart is functionally unaffected. In this study, we found that in the early stages of the disease, COVID-19 infection leads to a hyperdynamic circulatory state characterized by an elevated CI and low SVRI. The right heart function was unaffected, and pulmonary pressures were normal, despite the high CI, particularly in the low SVRI range. Lung recruitability in COVID-19 is moderately low (Pan et al., 2020) and blood diversion with cardiac output reduction may justify the reported oxygenation improvement at high Positive End Expiratory Pressure (PEEP).	./cache/cord-322919-5ty35rsy.txt	./txt/cord-322919-5ty35rsy.txt