id	sid	tid	token	lemma	pos
cord-276260-iccaqz8u	1	1	key	key	JJ
cord-276260-iccaqz8u	2	1	:	:	:
cord-276260-iccaqz8u	2	2	cord-276260-iccaqz8u	cord-276260-iccaqz8u	JJ
cord-276260-iccaqz8u	2	3	authors	author	NNS
cord-276260-iccaqz8u	2	4	:	:	:
cord-276260-iccaqz8u	3	1	Namsolleck	Namsolleck	NNP
cord-276260-iccaqz8u	3	2	,	,	,
cord-276260-iccaqz8u	3	3	Pawel	Pawel	NNP
cord-276260-iccaqz8u	3	4	;	;	:
cord-276260-iccaqz8u	3	5	Moll	Moll	NNP
cord-276260-iccaqz8u	3	6	,	,	,
cord-276260-iccaqz8u	3	7	Gert	Gert	NNP
cord-276260-iccaqz8u	3	8	N.	N.	NNP
cord-276260-iccaqz8u	3	9	title	title	NN
cord-276260-iccaqz8u	3	10	:	:	:
cord-276260-iccaqz8u	3	11	Does	do	VBZ
cord-276260-iccaqz8u	3	12	activation	activation	NN
cord-276260-iccaqz8u	3	13	of	of	IN
cord-276260-iccaqz8u	3	14	the	the	DT
cord-276260-iccaqz8u	3	15	protective	protective	JJ
cord-276260-iccaqz8u	3	16	Renin	Renin	NNP
cord-276260-iccaqz8u	3	17	-	-	HYPH
cord-276260-iccaqz8u	3	18	Angiotensin	Angiotensin	NNP
cord-276260-iccaqz8u	3	19	System	System	NNP
cord-276260-iccaqz8u	3	20	have	have	VBP
cord-276260-iccaqz8u	3	21	therapeutic	therapeutic	JJ
cord-276260-iccaqz8u	3	22	potential	potential	NN
cord-276260-iccaqz8u	3	23	in	in	IN
cord-276260-iccaqz8u	3	24	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	3	25	?	?	.
cord-276260-iccaqz8u	4	1	date	date	NN
cord-276260-iccaqz8u	4	2	:	:	:
cord-276260-iccaqz8u	4	3	2020	2020	CD
cord-276260-iccaqz8u	4	4	-	-	HYPH
cord-276260-iccaqz8u	4	5	08	08	CD
cord-276260-iccaqz8u	4	6	-	-	SYM
cord-276260-iccaqz8u	4	7	17	17	CD
cord-276260-iccaqz8u	4	8	journal	journal	NN
cord-276260-iccaqz8u	4	9	:	:	:
cord-276260-iccaqz8u	5	1	Mol	Mol	NNP
cord-276260-iccaqz8u	5	2	Med	Med	NNP
cord-276260-iccaqz8u	5	3	DOI	doi	NN
cord-276260-iccaqz8u	5	4	:	:	:
cord-276260-iccaqz8u	5	5	10.1186	10.1186	CD
cord-276260-iccaqz8u	5	6	/	/	SYM
cord-276260-iccaqz8u	5	7	s10020	s10020	NN
cord-276260-iccaqz8u	5	8	-	-	HYPH
cord-276260-iccaqz8u	5	9	020	020	CD
cord-276260-iccaqz8u	5	10	-	-	HYPH
cord-276260-iccaqz8u	5	11	00211	00211	CD
cord-276260-iccaqz8u	5	12	-	-	SYM
cord-276260-iccaqz8u	5	13	0	0	CD
cord-276260-iccaqz8u	5	14	sha	sha	NN
cord-276260-iccaqz8u	5	15	:	:	:
cord-276260-iccaqz8u	5	16	2ecda4f1df5c5d08ae3f908b588426cb40b281af	2ecda4f1df5c5d08ae3f908b588426cb40b281af	CD
cord-276260-iccaqz8u	5	17	doc_id	doc_id	CD
cord-276260-iccaqz8u	5	18	:	:	:
cord-276260-iccaqz8u	5	19	276260	276260	CD
cord-276260-iccaqz8u	5	20	cord_uid	cord_uid	NNS
cord-276260-iccaqz8u	5	21	:	:	:
cord-276260-iccaqz8u	5	22	iccaqz8u	iccaqz8u	NNP
cord-276260-iccaqz8u	6	1	Infection	infection	NN
cord-276260-iccaqz8u	6	2	of	of	IN
cord-276260-iccaqz8u	6	3	lung	lung	NN
cord-276260-iccaqz8u	6	4	cells	cell	NNS
cord-276260-iccaqz8u	6	5	by	by	IN
cord-276260-iccaqz8u	6	6	the	the	DT
cord-276260-iccaqz8u	6	7	corona	corona	NN
cord-276260-iccaqz8u	6	8	virus	virus	NN
cord-276260-iccaqz8u	6	9	results	result	VBZ
cord-276260-iccaqz8u	6	10	in	in	IN
cord-276260-iccaqz8u	6	11	a	a	DT
cord-276260-iccaqz8u	6	12	loss	loss	NN
cord-276260-iccaqz8u	6	13	of	of	IN
cord-276260-iccaqz8u	6	14	the	the	DT
cord-276260-iccaqz8u	6	15	balance	balance	NN
cord-276260-iccaqz8u	6	16	between	between	IN
cord-276260-iccaqz8u	6	17	,	,	,
cord-276260-iccaqz8u	6	18	on	on	IN
cord-276260-iccaqz8u	6	19	the	the	DT
cord-276260-iccaqz8u	6	20	one	one	CD
cord-276260-iccaqz8u	6	21	hand	hand	NN
cord-276260-iccaqz8u	6	22	,	,	,
cord-276260-iccaqz8u	6	23	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	6	24	II	II	NNP
cord-276260-iccaqz8u	6	25	-	-	HYPH
cord-276260-iccaqz8u	6	26	mediated	mediate	VBN
cord-276260-iccaqz8u	6	27	stimulation	stimulation	NN
cord-276260-iccaqz8u	6	28	of	of	IN
cord-276260-iccaqz8u	6	29	the	the	DT
cord-276260-iccaqz8u	6	30	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	6	31	II	II	NNP
cord-276260-iccaqz8u	6	32	type	type	NN
cord-276260-iccaqz8u	6	33	1	1	CD
cord-276260-iccaqz8u	6	34	receptor	receptor	NN
cord-276260-iccaqz8u	6	35	and	and	CC
cord-276260-iccaqz8u	6	36	,	,	,
cord-276260-iccaqz8u	6	37	on	on	IN
cord-276260-iccaqz8u	6	38	the	the	DT
cord-276260-iccaqz8u	6	39	other	other	JJ
cord-276260-iccaqz8u	6	40	hand	hand	NN
cord-276260-iccaqz8u	6	41	,	,	,
cord-276260-iccaqz8u	6	42	stimulation	stimulation	NN
cord-276260-iccaqz8u	6	43	of	of	IN
cord-276260-iccaqz8u	6	44	the	the	DT
cord-276260-iccaqz8u	6	45	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	6	46	II	II	NNP
cord-276260-iccaqz8u	6	47	type	type	NN
cord-276260-iccaqz8u	6	48	2	2	CD
cord-276260-iccaqz8u	6	49	receptor	receptor	NN
cord-276260-iccaqz8u	6	50	and/or	and/or	CC
cord-276260-iccaqz8u	6	51	the	the	DT
cord-276260-iccaqz8u	6	52	Mas	Mas	NNP
cord-276260-iccaqz8u	6	53	receptor	receptor	NN
cord-276260-iccaqz8u	6	54	.	.	.
cord-276260-iccaqz8u	7	1	The	the	DT
cord-276260-iccaqz8u	7	2	unbalanced	unbalanced	JJ
cord-276260-iccaqz8u	7	3	enhanced	enhanced	JJ
cord-276260-iccaqz8u	7	4	stimulation	stimulation	NN
cord-276260-iccaqz8u	7	5	of	of	IN
cord-276260-iccaqz8u	7	6	the	the	DT
cord-276260-iccaqz8u	7	7	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	7	8	II	II	NNP
cord-276260-iccaqz8u	7	9	type	type	NN
cord-276260-iccaqz8u	7	10	1	1	CD
cord-276260-iccaqz8u	7	11	receptor	receptor	NN
cord-276260-iccaqz8u	7	12	causes	cause	VBZ
cord-276260-iccaqz8u	7	13	inflammation	inflammation	NN
cord-276260-iccaqz8u	7	14	,	,	,
cord-276260-iccaqz8u	7	15	edema	edema	NN
cord-276260-iccaqz8u	7	16	and	and	CC
cord-276260-iccaqz8u	7	17	contributes	contribute	VBZ
cord-276260-iccaqz8u	7	18	to	to	IN
cord-276260-iccaqz8u	7	19	the	the	DT
cord-276260-iccaqz8u	7	20	pathogenesis	pathogenesis	NN
cord-276260-iccaqz8u	7	21	of	of	IN
cord-276260-iccaqz8u	7	22	severe	severe	JJ
cord-276260-iccaqz8u	7	23	acute	acute	JJ
cord-276260-iccaqz8u	7	24	respiratory	respiratory	JJ
cord-276260-iccaqz8u	7	25	distress	distress	NN
cord-276260-iccaqz8u	7	26	syndrome	syndrome	NN
cord-276260-iccaqz8u	7	27	.	.	.
cord-276260-iccaqz8u	8	1	Here	here	RB
cord-276260-iccaqz8u	8	2	we	-PRON-	PRP
cord-276260-iccaqz8u	8	3	hypothesize	hypothesize	VBP
cord-276260-iccaqz8u	8	4	that	that	IN
cord-276260-iccaqz8u	8	5	stable	stable	JJ
cord-276260-iccaqz8u	8	6	,	,	,
cord-276260-iccaqz8u	8	7	receptor	receptor	NN
cord-276260-iccaqz8u	8	8	-	-	HYPH
cord-276260-iccaqz8u	8	9	specific	specific	JJ
cord-276260-iccaqz8u	8	10	agonists	agonist	NNS
cord-276260-iccaqz8u	8	11	of	of	IN
cord-276260-iccaqz8u	8	12	the	the	DT
cord-276260-iccaqz8u	8	13	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	8	14	II	II	NNP
cord-276260-iccaqz8u	8	15	type	type	NN
cord-276260-iccaqz8u	8	16	2	2	CD
cord-276260-iccaqz8u	8	17	receptor	receptor	NN
cord-276260-iccaqz8u	8	18	and	and	CC
cord-276260-iccaqz8u	8	19	of	of	IN
cord-276260-iccaqz8u	8	20	the	the	DT
cord-276260-iccaqz8u	8	21	Mas	Mas	NNP
cord-276260-iccaqz8u	8	22	receptor	receptor	NN
cord-276260-iccaqz8u	8	23	are	be	VBP
cord-276260-iccaqz8u	8	24	molecular	molecular	JJ
cord-276260-iccaqz8u	8	25	medicines	medicine	NNS
cord-276260-iccaqz8u	8	26	to	to	TO
cord-276260-iccaqz8u	8	27	treat	treat	VB
cord-276260-iccaqz8u	8	28	COVID-19	covid-19	JJ
cord-276260-iccaqz8u	8	29	patients	patient	NNS
cord-276260-iccaqz8u	8	30	.	.	.
cord-276260-iccaqz8u	9	1	These	these	DT
cord-276260-iccaqz8u	9	2	agonists	agonist	NNS
cord-276260-iccaqz8u	9	3	have	have	VBP
cord-276260-iccaqz8u	9	4	therapeutic	therapeutic	JJ
cord-276260-iccaqz8u	9	5	potential	potential	NN
cord-276260-iccaqz8u	9	6	in	in	IN
cord-276260-iccaqz8u	9	7	the	the	DT
cord-276260-iccaqz8u	9	8	acute	acute	JJ
cord-276260-iccaqz8u	9	9	disease	disease	NN
cord-276260-iccaqz8u	9	10	but	but	CC
cord-276260-iccaqz8u	9	11	in	in	IN
cord-276260-iccaqz8u	9	12	addition	addition	NN
cord-276260-iccaqz8u	9	13	may	may	MD
cord-276260-iccaqz8u	9	14	reduce	reduce	VB
cord-276260-iccaqz8u	9	15	COVID-19-associated	covid-19-associated	JJ
cord-276260-iccaqz8u	9	16	long	long	JJ
cord-276260-iccaqz8u	9	17	-	-	HYPH
cord-276260-iccaqz8u	9	18	term	term	NN
cord-276260-iccaqz8u	9	19	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	9	20	dysfunction	dysfunction	NN
cord-276260-iccaqz8u	9	21	and	and	CC
cord-276260-iccaqz8u	9	22	overall	overall	JJ
cord-276260-iccaqz8u	9	23	end	end	NN
cord-276260-iccaqz8u	9	24	-	-	HYPH
cord-276260-iccaqz8u	9	25	organ	organ	NN
cord-276260-iccaqz8u	9	26	damage	damage	NN
cord-276260-iccaqz8u	9	27	of	of	IN
cord-276260-iccaqz8u	9	28	this	this	DT
cord-276260-iccaqz8u	9	29	disease	disease	NN
cord-276260-iccaqz8u	9	30	.	.	.
cord-276260-iccaqz8u	10	1	Recent	recent	JJ
cord-276260-iccaqz8u	10	2	publications	publication	NNS
cord-276260-iccaqz8u	10	3	highlight	highlight	VBP
cord-276260-iccaqz8u	10	4	ACE2	ACE2	NNP
cord-276260-iccaqz8u	10	5	as	as	IN
cord-276260-iccaqz8u	10	6	a	a	DT
cord-276260-iccaqz8u	10	7	cell	cell	NN
cord-276260-iccaqz8u	10	8	-	-	HYPH
cord-276260-iccaqz8u	10	9	entry	entry	NN
cord-276260-iccaqz8u	10	10	receptor	receptor	NN
cord-276260-iccaqz8u	10	11	for	for	IN
cord-276260-iccaqz8u	10	12	SARS	SARS	NNP
cord-276260-iccaqz8u	10	13	-	-	HYPH
cord-276260-iccaqz8u	10	14	CoV	CoV	NNP
cord-276260-iccaqz8u	10	15	and	and	CC
cord-276260-iccaqz8u	10	16	SARS	SARS	NNP
cord-276260-iccaqz8u	10	17	-	-	HYPH
cord-276260-iccaqz8u	10	18	CoV-2	CoV-2	NNP
cord-276260-iccaqz8u	10	19	.	.	.
cord-276260-iccaqz8u	11	1	Less	Less	JJR
cord-276260-iccaqz8u	11	2	attention	attention	NN
cord-276260-iccaqz8u	11	3	is	be	VBZ
cord-276260-iccaqz8u	11	4	given	give	VBN
cord-276260-iccaqz8u	11	5	to	to	IN
cord-276260-iccaqz8u	11	6	other	other	JJ
cord-276260-iccaqz8u	11	7	,	,	,
cord-276260-iccaqz8u	11	8	in	in	IN
cord-276260-iccaqz8u	11	9	particular	particular	JJ
cord-276260-iccaqz8u	11	10	protective	protective	JJ
cord-276260-iccaqz8u	11	11	,	,	,
cord-276260-iccaqz8u	11	12	components	component	NNS
cord-276260-iccaqz8u	11	13	of	of	IN
cord-276260-iccaqz8u	11	14	the	the	DT
cord-276260-iccaqz8u	11	15	Renin	Renin	NNP
cord-276260-iccaqz8u	11	16	Angiotensin	Angiotensin	NNP
cord-276260-iccaqz8u	11	17	System	System	NNP
cord-276260-iccaqz8u	11	18	(	(	-LRB-
cord-276260-iccaqz8u	11	19	RAS	RAS	NNP
cord-276260-iccaqz8u	11	20	)	)	-RRB-
cord-276260-iccaqz8u	11	21	(	(	-LRB-
cord-276260-iccaqz8u	11	22	Unger	Unger	NNP
cord-276260-iccaqz8u	11	23	et	et	NNP
cord-276260-iccaqz8u	11	24	al	al	NNP
cord-276260-iccaqz8u	11	25	.	.	NNP
cord-276260-iccaqz8u	11	26	2015	2015	CD
cord-276260-iccaqz8u	11	27	)	)	-RRB-
cord-276260-iccaqz8u	11	28	.	.	.
cord-276260-iccaqz8u	12	1	RAS	RAS	NNP
cord-276260-iccaqz8u	12	2	has	have	VBZ
cord-276260-iccaqz8u	12	3	a	a	DT
cord-276260-iccaqz8u	12	4	double	double	JJ
cord-276260-iccaqz8u	12	5	nature	nature	NN
cord-276260-iccaqz8u	12	6	,	,	,
cord-276260-iccaqz8u	12	7	like	like	IN
cord-276260-iccaqz8u	12	8	the	the	DT
cord-276260-iccaqz8u	12	9	two	two	CD
cord-276260-iccaqz8u	12	10	-	-	HYPH
cord-276260-iccaqz8u	12	11	faced	face	VBN
cord-276260-iccaqz8u	12	12	ancient	ancient	JJ
cord-276260-iccaqz8u	12	13	Roman	roman	JJ
cord-276260-iccaqz8u	12	14	god	god	NN
cord-276260-iccaqz8u	12	15	Janus	Janus	NNP
cord-276260-iccaqz8u	12	16	,	,	,
cord-276260-iccaqz8u	12	17	which	which	WDT
cord-276260-iccaqz8u	12	18	simultaneously	simultaneously	RB
cord-276260-iccaqz8u	12	19	looks	look	VBZ
cord-276260-iccaqz8u	12	20	in	in	IN
cord-276260-iccaqz8u	12	21	opposite	opposite	JJ
cord-276260-iccaqz8u	12	22	directions	direction	NNS
cord-276260-iccaqz8u	12	23	.	.	.
cord-276260-iccaqz8u	13	1	The	the	DT
cord-276260-iccaqz8u	13	2	Detrimental	Detrimental	NNP
cord-276260-iccaqz8u	13	3	Arm	Arm	NNP
cord-276260-iccaqz8u	13	4	of	of	IN
cord-276260-iccaqz8u	13	5	RAS	RAS	NNP
cord-276260-iccaqz8u	13	6	is	be	VBZ
cord-276260-iccaqz8u	13	7	formed	form	VBN
cord-276260-iccaqz8u	13	8	by	by	IN
cord-276260-iccaqz8u	13	9	the	the	DT
cord-276260-iccaqz8u	13	10	ACE	ACE	NNP
cord-276260-iccaqz8u	13	11	-	-	HYPH
cord-276260-iccaqz8u	13	12	Angiotensin	Angiotensin	NNP
cord-276260-iccaqz8u	13	13	II	II	NNP
cord-276260-iccaqz8u	13	14	(	(	-LRB-
cord-276260-iccaqz8u	13	15	Ang	Ang	NNP
cord-276260-iccaqz8u	13	16	II)-angiotensin	II)-angiotensin	NNP
cord-276260-iccaqz8u	13	17	II	II	NNP
cord-276260-iccaqz8u	13	18	type	type	NN
cord-276260-iccaqz8u	13	19	1	1	CD
cord-276260-iccaqz8u	13	20	receptor	receptor	NN
cord-276260-iccaqz8u	13	21	(	(	-LRB-
cord-276260-iccaqz8u	13	22	AT	at	IN
cord-276260-iccaqz8u	13	23	1	1	CD
cord-276260-iccaqz8u	13	24	R	r	NN
cord-276260-iccaqz8u	13	25	)	)	-RRB-
cord-276260-iccaqz8u	13	26	axis	axis	NN
cord-276260-iccaqz8u	13	27	.	.	.
cord-276260-iccaqz8u	14	1	Limiting	limit	VBG
cord-276260-iccaqz8u	14	2	the	the	DT
cord-276260-iccaqz8u	14	3	detrimental	detrimental	JJ
cord-276260-iccaqz8u	14	4	effects	effect	NNS
cord-276260-iccaqz8u	14	5	of	of	IN
cord-276260-iccaqz8u	14	6	AT	at	NN
cord-276260-iccaqz8u	14	7	1	1	CD
cord-276260-iccaqz8u	14	8	R	r	NN
cord-276260-iccaqz8u	14	9	by	by	IN
cord-276260-iccaqz8u	14	10	AT	at	NN
cord-276260-iccaqz8u	14	11	1	1	CD
cord-276260-iccaqz8u	14	12	R	r	NN
cord-276260-iccaqz8u	14	13	blockers	blocker	NNS
cord-276260-iccaqz8u	14	14	(	(	-LRB-
cord-276260-iccaqz8u	14	15	ARBs	arb	NNS
cord-276260-iccaqz8u	14	16	)	)	-RRB-
cord-276260-iccaqz8u	14	17	or	or	CC
cord-276260-iccaqz8u	14	18	by	by	IN
cord-276260-iccaqz8u	14	19	inhibiting	inhibit	VBG
cord-276260-iccaqz8u	14	20	RAS	RAS	NNP
cord-276260-iccaqz8u	14	21	via	via	IN
cord-276260-iccaqz8u	14	22	ACE	ace	NN
cord-276260-iccaqz8u	14	23	inhibitors	inhibitor	NNS
cord-276260-iccaqz8u	14	24	(	(	-LRB-
cord-276260-iccaqz8u	14	25	ACEi	ACEi	NNP
cord-276260-iccaqz8u	14	26	)	)	-RRB-
cord-276260-iccaqz8u	14	27	is	be	VBZ
cord-276260-iccaqz8u	14	28	generally	generally	RB
cord-276260-iccaqz8u	14	29	well	well	RB
cord-276260-iccaqz8u	14	30	-	-	HYPH
cord-276260-iccaqz8u	14	31	established	establish	VBN
cord-276260-iccaqz8u	14	32	.	.	.
cord-276260-iccaqz8u	15	1	However	however	RB
cord-276260-iccaqz8u	15	2	,	,	,
cord-276260-iccaqz8u	15	3	the	the	DT
cord-276260-iccaqz8u	15	4	use	use	NN
cord-276260-iccaqz8u	15	5	of	of	IN
cord-276260-iccaqz8u	15	6	ARBs	arb	NNS
cord-276260-iccaqz8u	15	7	and	and	CC
cord-276260-iccaqz8u	15	8	ACEi	acei	NN
cord-276260-iccaqz8u	15	9	in	in	IN
cord-276260-iccaqz8u	15	10	coronavirus	coronavirus	NN
cord-276260-iccaqz8u	15	11	disease-2019	disease-2019	NNP
cord-276260-iccaqz8u	15	12	(	(	-LRB-
cord-276260-iccaqz8u	15	13	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	15	14	)	)	-RRB-
cord-276260-iccaqz8u	15	15	has	have	VBZ
cord-276260-iccaqz8u	15	16	been	be	VBN
cord-276260-iccaqz8u	15	17	subject	subject	JJ
cord-276260-iccaqz8u	15	18	of	of	IN
cord-276260-iccaqz8u	15	19	debate	debate	NN
cord-276260-iccaqz8u	15	20	.	.	.
cord-276260-iccaqz8u	16	1	On	on	IN
cord-276260-iccaqz8u	16	2	the	the	DT
cord-276260-iccaqz8u	16	3	other	other	JJ
cord-276260-iccaqz8u	16	4	hand	hand	NN
cord-276260-iccaqz8u	16	5	,	,	,
cord-276260-iccaqz8u	16	6	as	as	IN
cord-276260-iccaqz8u	16	7	part	part	NN
cord-276260-iccaqz8u	16	8	of	of	IN
cord-276260-iccaqz8u	16	9	the	the	DT
cord-276260-iccaqz8u	16	10	Protective	Protective	NNP
cord-276260-iccaqz8u	16	11	Arm	Arm	NNP
cord-276260-iccaqz8u	16	12	of	of	IN
cord-276260-iccaqz8u	16	13	RAS	RAS	NNP
cord-276260-iccaqz8u	16	14	,	,	,
cord-276260-iccaqz8u	16	15	Ang	Ang	NNP
cord-276260-iccaqz8u	16	16	II	II	NNP
cord-276260-iccaqz8u	16	17	also	also	RB
cord-276260-iccaqz8u	16	18	stimulates	stimulate	VBZ
cord-276260-iccaqz8u	16	19	the	the	DT
cord-276260-iccaqz8u	16	20	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	16	21	II	II	NNP
cord-276260-iccaqz8u	16	22	type	type	NN
cord-276260-iccaqz8u	16	23	2	2	CD
cord-276260-iccaqz8u	16	24	receptor	receptor	NN
cord-276260-iccaqz8u	16	25	(	(	-LRB-
cord-276260-iccaqz8u	16	26	AT	at	IN
cord-276260-iccaqz8u	16	27	2	2	CD
cord-276260-iccaqz8u	16	28	R	r	NN
cord-276260-iccaqz8u	16	29	)	)	-RRB-
cord-276260-iccaqz8u	16	30	and	and	CC
cord-276260-iccaqz8u	16	31	this	this	DT
cord-276260-iccaqz8u	16	32	octapeptide	octapeptide	NN
cord-276260-iccaqz8u	16	33	can	can	MD
cord-276260-iccaqz8u	16	34	be	be	VB
cord-276260-iccaqz8u	16	35	further	further	RB
cord-276260-iccaqz8u	16	36	cleaved	cleave	VBN
cord-276260-iccaqz8u	16	37	by	by	IN
cord-276260-iccaqz8u	16	38	the	the	DT
cord-276260-iccaqz8u	16	39	carboxypeptidase	carboxypeptidase	NN
cord-276260-iccaqz8u	16	40	ACE2	ACE2	NNP
cord-276260-iccaqz8u	16	41	to	to	TO
cord-276260-iccaqz8u	16	42	yield	yield	VB
cord-276260-iccaqz8u	16	43	angiotensin-(1	angiotensin-(1	CD
cord-276260-iccaqz8u	16	44	-	-	SYM
cord-276260-iccaqz8u	16	45	7	7	CD
cord-276260-iccaqz8u	16	46	)	)	-RRB-
cord-276260-iccaqz8u	17	1	(	(	-LRB-
cord-276260-iccaqz8u	17	2	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	17	3	-	-	HYPH
cord-276260-iccaqz8u	17	4	7	7	CD
cord-276260-iccaqz8u	17	5	)	)	-RRB-
cord-276260-iccaqz8u	17	6	)	)	-RRB-
cord-276260-iccaqz8u	17	7	,	,	,
cord-276260-iccaqz8u	17	8	an	an	DT
cord-276260-iccaqz8u	17	9	agonist	agonist	NN
cord-276260-iccaqz8u	17	10	of	of	IN
cord-276260-iccaqz8u	17	11	the	the	DT
cord-276260-iccaqz8u	17	12	Mas	Mas	NNP
cord-276260-iccaqz8u	17	13	receptor	receptor	NN
cord-276260-iccaqz8u	17	14	(	(	-LRB-
cord-276260-iccaqz8u	17	15	MasR	MasR	NNP
cord-276260-iccaqz8u	17	16	)	)	-RRB-
cord-276260-iccaqz8u	17	17	.	.	.
cord-276260-iccaqz8u	18	1	The	the	DT
cord-276260-iccaqz8u	18	2	protective	protective	JJ
cord-276260-iccaqz8u	18	3	effects	effect	NNS
cord-276260-iccaqz8u	18	4	of	of	IN
cord-276260-iccaqz8u	18	5	AT	at	NN
cord-276260-iccaqz8u	18	6	2	2	CD
cord-276260-iccaqz8u	18	7	R	r	NN
cord-276260-iccaqz8u	18	8	and	and	CC
cord-276260-iccaqz8u	18	9	MasR	MasR	NNP
cord-276260-iccaqz8u	18	10	agonists	agonist	NNS
cord-276260-iccaqz8u	18	11	are	be	VBP
cord-276260-iccaqz8u	18	12	usually	usually	RB
cord-276260-iccaqz8u	18	13	opposite	opposite	JJ
cord-276260-iccaqz8u	18	14	to	to	IN
cord-276260-iccaqz8u	18	15	the	the	DT
cord-276260-iccaqz8u	18	16	detrimental	detrimental	JJ
cord-276260-iccaqz8u	18	17	effects	effect	NNS
cord-276260-iccaqz8u	18	18	of	of	IN
cord-276260-iccaqz8u	18	19	AT	at	NN
cord-276260-iccaqz8u	18	20	1	1	CD
cord-276260-iccaqz8u	18	21	R	r	NN
cord-276260-iccaqz8u	18	22	,	,	,
cord-276260-iccaqz8u	18	23	but	but	CC
cord-276260-iccaqz8u	18	24	their	-PRON-	PRP$
cord-276260-iccaqz8u	18	25	clinical	clinical	JJ
cord-276260-iccaqz8u	18	26	use	use	NN
cord-276260-iccaqz8u	18	27	,	,	,
cord-276260-iccaqz8u	18	28	in	in	IN
cord-276260-iccaqz8u	18	29	cases	case	NNS
cord-276260-iccaqz8u	18	30	of	of	IN
cord-276260-iccaqz8u	18	31	unbalance	unbalance	NN
cord-276260-iccaqz8u	18	32	between	between	IN
cord-276260-iccaqz8u	18	33	the	the	DT
cord-276260-iccaqz8u	18	34	two	two	CD
cord-276260-iccaqz8u	18	35	Arms	arm	NNS
cord-276260-iccaqz8u	18	36	of	of	IN
cord-276260-iccaqz8u	18	37	RAS	RAS	NNP
cord-276260-iccaqz8u	18	38	,	,	,
cord-276260-iccaqz8u	18	39	is	be	VBZ
cord-276260-iccaqz8u	18	40	insufficiently	insufficiently	RB
cord-276260-iccaqz8u	18	41	explored	explore	VBN
cord-276260-iccaqz8u	18	42	.	.	.
cord-276260-iccaqz8u	19	1	Endogenous	endogenous	JJ
cord-276260-iccaqz8u	19	2	ligands	ligand	NNS
cord-276260-iccaqz8u	19	3	of	of	IN
cord-276260-iccaqz8u	19	4	the	the	DT
cord-276260-iccaqz8u	19	5	RAS	RAS	NNP
cord-276260-iccaqz8u	19	6	receptors	receptor	NNS
cord-276260-iccaqz8u	19	7	are	be	VBP
cord-276260-iccaqz8u	19	8	rapidly	rapidly	RB
cord-276260-iccaqz8u	19	9	degraded	degrade	VBN
cord-276260-iccaqz8u	19	10	and	and	CC
cord-276260-iccaqz8u	19	11	lack	lack	JJ
cord-276260-iccaqz8u	19	12	receptor	receptor	NN
cord-276260-iccaqz8u	19	13	specificity	specificity	NN
cord-276260-iccaqz8u	19	14	.	.	.
cord-276260-iccaqz8u	20	1	Here	here	RB
cord-276260-iccaqz8u	20	2	we	-PRON-	PRP
cord-276260-iccaqz8u	20	3	consider	consider	VBP
cord-276260-iccaqz8u	20	4	therapeutic	therapeutic	JJ
cord-276260-iccaqz8u	20	5	perspectives	perspective	NNS
cord-276260-iccaqz8u	20	6	of	of	IN
cord-276260-iccaqz8u	20	7	stable	stable	JJ
cord-276260-iccaqz8u	20	8	and	and	CC
cord-276260-iccaqz8u	20	9	specific	specific	JJ
cord-276260-iccaqz8u	20	10	AT	at	IN
cord-276260-iccaqz8u	20	11	2	2	CD
cord-276260-iccaqz8u	20	12	R	r	NN
cord-276260-iccaqz8u	20	13	and	and	CC
cord-276260-iccaqz8u	20	14	MasR	MasR	NNP
cord-276260-iccaqz8u	20	15	agonists	agonist	NNS
cord-276260-iccaqz8u	20	16	in	in	IN
cord-276260-iccaqz8u	20	17	The	the	DT
cord-276260-iccaqz8u	20	18	balance	balance	NN
cord-276260-iccaqz8u	20	19	between	between	IN
cord-276260-iccaqz8u	20	20	the	the	DT
cord-276260-iccaqz8u	20	21	Detrimental	detrimental	JJ
cord-276260-iccaqz8u	20	22	and	and	CC
cord-276260-iccaqz8u	20	23	Protective	Protective	NNP
cord-276260-iccaqz8u	20	24	Arm	Arm	NNP
cord-276260-iccaqz8u	20	25	of	of	IN
cord-276260-iccaqz8u	20	26	RAS	RAS	NNP
cord-276260-iccaqz8u	20	27	is	be	VBZ
cord-276260-iccaqz8u	20	28	in	in	IN
cord-276260-iccaqz8u	20	29	several	several	JJ
cord-276260-iccaqz8u	20	30	aspects	aspect	NNS
cord-276260-iccaqz8u	20	31	seriously	seriously	RB
cord-276260-iccaqz8u	20	32	disturbed	disturb	VBN
cord-276260-iccaqz8u	20	33	in	in	IN
cord-276260-iccaqz8u	20	34	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	20	35	,	,	,
cord-276260-iccaqz8u	20	36	thus	thus	RB
cord-276260-iccaqz8u	20	37	causing	cause	VBG
cord-276260-iccaqz8u	20	38	a	a	DT
cord-276260-iccaqz8u	20	39	potentially	potentially	RB
cord-276260-iccaqz8u	20	40	lethal	lethal	JJ
cord-276260-iccaqz8u	20	41	disease	disease	NN
cord-276260-iccaqz8u	20	42	(	(	-LRB-
cord-276260-iccaqz8u	20	43	Fig	fig	NN
cord-276260-iccaqz8u	20	44	.	.	.
cord-276260-iccaqz8u	20	45	1	1	CD
cord-276260-iccaqz8u	20	46	)	)	-RRB-
cord-276260-iccaqz8u	20	47	.	.	.
cord-276260-iccaqz8u	21	1	After	after	IN
cord-276260-iccaqz8u	21	2	the	the	DT
cord-276260-iccaqz8u	21	3	SARS	SARS	NNP
cord-276260-iccaqz8u	21	4	-	-	HYPH
cord-276260-iccaqz8u	21	5	CoV	CoV	NNP
cord-276260-iccaqz8u	21	6	cell	cell	NN
cord-276260-iccaqz8u	21	7	-	-	HYPH
cord-276260-iccaqz8u	21	8	entry	entry	NN
cord-276260-iccaqz8u	21	9	following	follow	VBG
cord-276260-iccaqz8u	21	10	ACE2-interaction	ace2-interaction	NN
cord-276260-iccaqz8u	21	11	,	,	,
cord-276260-iccaqz8u	21	12	subsequent	subsequent	JJ
cord-276260-iccaqz8u	21	13	down	down	JJ
cord-276260-iccaqz8u	21	14	-	-	HYPH
cord-276260-iccaqz8u	21	15	regulation	regulation	NN
cord-276260-iccaqz8u	21	16	of	of	IN
cord-276260-iccaqz8u	21	17	cell	cell	NN
cord-276260-iccaqz8u	21	18	surface	surface	NN
cord-276260-iccaqz8u	21	19	ACE2	ACE2	NNP
cord-276260-iccaqz8u	21	20	is	be	VBZ
cord-276260-iccaqz8u	21	21	observed	observe	VBN
cord-276260-iccaqz8u	22	1	(	(	-LRB-
cord-276260-iccaqz8u	22	2	Kuba	Kuba	NNP
cord-276260-iccaqz8u	22	3	et	et	NNP
cord-276260-iccaqz8u	22	4	al	al	NNP
cord-276260-iccaqz8u	22	5	.	.	NNP
cord-276260-iccaqz8u	22	6	2005	2005	CD
cord-276260-iccaqz8u	22	7	)	)	-RRB-
cord-276260-iccaqz8u	22	8	.	.	.
cord-276260-iccaqz8u	23	1	Since	since	IN
cord-276260-iccaqz8u	23	2	SARS	SARS	NNP
cord-276260-iccaqz8u	23	3	-	-	HYPH
cord-276260-iccaqz8u	23	4	CoV-2	CoV-2	NNP
cord-276260-iccaqz8u	23	5	also	also	RB
cord-276260-iccaqz8u	23	6	targets	target	VBZ
cord-276260-iccaqz8u	23	7	ACE2	ACE2	NNP
cord-276260-iccaqz8u	23	8	,	,	,
cord-276260-iccaqz8u	23	9	likewise	likewise	RB
cord-276260-iccaqz8u	23	10	downregulation	downregulation	NN
cord-276260-iccaqz8u	23	11	of	of	IN
cord-276260-iccaqz8u	23	12	ACE2	ACE2	NNP
cord-276260-iccaqz8u	23	13	is	be	VBZ
cord-276260-iccaqz8u	23	14	expected	expect	VBN
cord-276260-iccaqz8u	23	15	.	.	.
cord-276260-iccaqz8u	24	1	Reduced	reduce	VBN
cord-276260-iccaqz8u	24	2	membrane	membrane	NN
cord-276260-iccaqz8u	24	3	expression	expression	NN
cord-276260-iccaqz8u	24	4	of	of	IN
cord-276260-iccaqz8u	24	5	ACE2	ACE2	NNP
cord-276260-iccaqz8u	24	6	enhances	enhance	VBZ
cord-276260-iccaqz8u	24	7	the	the	DT
cord-276260-iccaqz8u	24	8	inflammatory	inflammatory	JJ
cord-276260-iccaqz8u	24	9	response	response	NN
cord-276260-iccaqz8u	24	10	to	to	IN
cord-276260-iccaqz8u	24	11	the	the	DT
cord-276260-iccaqz8u	24	12	virus	virus	NN
cord-276260-iccaqz8u	24	13	.	.	.
cord-276260-iccaqz8u	25	1	COVID-19	covid-19	JJ
cord-276260-iccaqz8u	25	2	infection	infection	NN
cord-276260-iccaqz8u	25	3	furthermore	furthermore	RB
cord-276260-iccaqz8u	25	4	causes	cause	VBZ
cord-276260-iccaqz8u	25	5	an	an	DT
cord-276260-iccaqz8u	25	6	increase	increase	NN
cord-276260-iccaqz8u	25	7	in	in	IN
cord-276260-iccaqz8u	25	8	the	the	DT
cord-276260-iccaqz8u	25	9	decapeptide	decapeptide	NN
cord-276260-iccaqz8u	26	1	Ang	Ang	NNP
cord-276260-iccaqz8u	26	2	I	I	NNP
cord-276260-iccaqz8u	26	3	and	and	CC
cord-276260-iccaqz8u	26	4	the	the	DT
cord-276260-iccaqz8u	26	5	octapeptide	octapeptide	NNP
cord-276260-iccaqz8u	26	6	Ang	Ang	NNP
cord-276260-iccaqz8u	26	7	II	II	NNP
cord-276260-iccaqz8u	26	8	,	,	,
cord-276260-iccaqz8u	26	9	whereas	whereas	IN
cord-276260-iccaqz8u	26	10	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	26	11	-	-	HYPH
cord-276260-iccaqz8u	26	12	7	7	CD
cord-276260-iccaqz8u	26	13	)	)	-RRB-
cord-276260-iccaqz8u	26	14	levels	level	NNS
cord-276260-iccaqz8u	26	15	decrease	decrease	NN
cord-276260-iccaqz8u	26	16	.	.	.
cord-276260-iccaqz8u	27	1	Thereby	thereby	RB
cord-276260-iccaqz8u	27	2	detrimental	detrimental	JJ
cord-276260-iccaqz8u	27	3	Ang	Ang	NNP
cord-276260-iccaqz8u	27	4	II	II	NNP
cord-276260-iccaqz8u	27	5	-	-	HYPH
cord-276260-iccaqz8u	27	6	mediated	mediate	VBN
cord-276260-iccaqz8u	27	7	stimulation	stimulation	NN
cord-276260-iccaqz8u	27	8	of	of	IN
cord-276260-iccaqz8u	27	9	AT	at	NN
cord-276260-iccaqz8u	27	10	1	1	CD
cord-276260-iccaqz8u	27	11	R	r	NN
cord-276260-iccaqz8u	27	12	is	be	VBZ
cord-276260-iccaqz8u	27	13	enhanced	enhance	VBN
cord-276260-iccaqz8u	27	14	whereas	whereas	IN
cord-276260-iccaqz8u	27	15	protective	protective	JJ
cord-276260-iccaqz8u	27	16	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	27	17	-	-	HYPH
cord-276260-iccaqz8u	27	18	7)-mediated	7)-mediated	CD
cord-276260-iccaqz8u	27	19	stimulation	stimulation	NN
cord-276260-iccaqz8u	27	20	of	of	IN
cord-276260-iccaqz8u	27	21	MasR	MasR	NNP
cord-276260-iccaqz8u	27	22	is	be	VBZ
cord-276260-iccaqz8u	27	23	decreased	decrease	VBN
cord-276260-iccaqz8u	27	24	.	.	.
cord-276260-iccaqz8u	28	1	AT	at	IN
cord-276260-iccaqz8u	28	2	1	1	CD
cord-276260-iccaqz8u	28	3	R	r	NN
cord-276260-iccaqz8u	28	4	stimulation	stimulation	NN
cord-276260-iccaqz8u	28	5	reduces	reduce	VBZ
cord-276260-iccaqz8u	28	6	alveolar	alveolar	NN
cord-276260-iccaqz8u	28	7	cell	cell	NN
cord-276260-iccaqz8u	28	8	survival	survival	NN
cord-276260-iccaqz8u	28	9	.	.	.
cord-276260-iccaqz8u	29	1	It	-PRON-	PRP
cord-276260-iccaqz8u	29	2	also	also	RB
cord-276260-iccaqz8u	29	3	causes	cause	VBZ
cord-276260-iccaqz8u	29	4	inflammation	inflammation	NN
cord-276260-iccaqz8u	29	5	and	and	CC
cord-276260-iccaqz8u	29	6	an	an	DT
cord-276260-iccaqz8u	29	7	increase	increase	NN
cord-276260-iccaqz8u	29	8	in	in	IN
cord-276260-iccaqz8u	29	9	vascular	vascular	JJ
cord-276260-iccaqz8u	29	10	permeability	permeability	NN
cord-276260-iccaqz8u	29	11	(	(	-LRB-
cord-276260-iccaqz8u	29	12	Huertas	Huertas	NNP
cord-276260-iccaqz8u	29	13	et	et	NNP
cord-276260-iccaqz8u	29	14	al	al	NNP
cord-276260-iccaqz8u	29	15	.	.	NNP
cord-276260-iccaqz8u	29	16	2020	2020	CD
cord-276260-iccaqz8u	29	17	)	)	-RRB-
cord-276260-iccaqz8u	29	18	.	.	.
cord-276260-iccaqz8u	30	1	As	as	IN
cord-276260-iccaqz8u	30	2	a	a	DT
cord-276260-iccaqz8u	30	3	result	result	NN
cord-276260-iccaqz8u	30	4	,	,	,
cord-276260-iccaqz8u	30	5	edema	edema	NN
cord-276260-iccaqz8u	30	6	is	be	VBZ
cord-276260-iccaqz8u	30	7	accumulating	accumulate	VBG
cord-276260-iccaqz8u	30	8	in	in	IN
cord-276260-iccaqz8u	30	9	the	the	DT
cord-276260-iccaqz8u	30	10	alveoli	alveolus	NNS
cord-276260-iccaqz8u	30	11	which	which	WDT
cord-276260-iccaqz8u	30	12	hampers	hamper	VBZ
cord-276260-iccaqz8u	30	13	gas	gas	NN
cord-276260-iccaqz8u	30	14	-	-	HYPH
cord-276260-iccaqz8u	30	15	exchange	exchange	NN
cord-276260-iccaqz8u	30	16	leading	lead	VBG
cord-276260-iccaqz8u	30	17	to	to	IN
cord-276260-iccaqz8u	30	18	lower	low	JJR
cord-276260-iccaqz8u	30	19	oxygen	oxygen	NN
cord-276260-iccaqz8u	30	20	levels	level	NNS
cord-276260-iccaqz8u	30	21	.	.	.
cord-276260-iccaqz8u	31	1	Taken	take	VBN
cord-276260-iccaqz8u	31	2	together	together	RB
cord-276260-iccaqz8u	31	3	this	this	DT
cord-276260-iccaqz8u	31	4	adds	add	VBZ
cord-276260-iccaqz8u	31	5	to	to	IN
cord-276260-iccaqz8u	31	6	the	the	DT
cord-276260-iccaqz8u	31	7	severity	severity	NN
cord-276260-iccaqz8u	31	8	of	of	IN
cord-276260-iccaqz8u	31	9	the	the	DT
cord-276260-iccaqz8u	31	10	acute	acute	JJ
cord-276260-iccaqz8u	31	11	respiratory	respiratory	JJ
cord-276260-iccaqz8u	31	12	distress	distress	NN
cord-276260-iccaqz8u	31	13	.	.	.
cord-276260-iccaqz8u	32	1	Reduction	reduction	NN
cord-276260-iccaqz8u	32	2	of	of	IN
cord-276260-iccaqz8u	32	3	the	the	DT
cord-276260-iccaqz8u	32	4	unbalance	unbalance	NN
cord-276260-iccaqz8u	32	5	in	in	IN
cord-276260-iccaqz8u	32	6	the	the	DT
cord-276260-iccaqz8u	32	7	RAS	RAS	NNP
cord-276260-iccaqz8u	32	8	by	by	IN
cord-276260-iccaqz8u	32	9	inhibition	inhibition	NN
cord-276260-iccaqz8u	32	10	of	of	IN
cord-276260-iccaqz8u	32	11	the	the	DT
cord-276260-iccaqz8u	32	12	Detrimental	Detrimental	NNP
cord-276260-iccaqz8u	32	13	Arm	Arm	NNP
cord-276260-iccaqz8u	32	14	might	may	MD
cord-276260-iccaqz8u	32	15	be	be	VB
cord-276260-iccaqz8u	32	16	reached	reach	VBN
cord-276260-iccaqz8u	32	17	by	by	IN
cord-276260-iccaqz8u	32	18	either	either	CC
cord-276260-iccaqz8u	32	19	an	an	DT
cord-276260-iccaqz8u	32	20	ARB	ARB	NNP
cord-276260-iccaqz8u	32	21	or	or	CC
cord-276260-iccaqz8u	32	22	an	an	DT
cord-276260-iccaqz8u	32	23	ACEi	acei	NN
cord-276260-iccaqz8u	32	24	.	.	.
cord-276260-iccaqz8u	33	1	The	the	DT
cord-276260-iccaqz8u	33	2	combined	combine	VBN
cord-276260-iccaqz8u	33	3	use	use	NN
cord-276260-iccaqz8u	33	4	of	of	IN
cord-276260-iccaqz8u	33	5	ARBs	arb	NNS
cord-276260-iccaqz8u	33	6	and	and	CC
cord-276260-iccaqz8u	33	7	ACEi	acei	NN
cord-276260-iccaqz8u	33	8	is	be	VBZ
cord-276260-iccaqz8u	33	9	prohibited	prohibit	VBN
cord-276260-iccaqz8u	33	10	,	,	,
cord-276260-iccaqz8u	33	11	but	but	CC
cord-276260-iccaqz8u	33	12	their	-PRON-	PRP$
cord-276260-iccaqz8u	33	13	single	single	JJ
cord-276260-iccaqz8u	33	14	use	use	NN
cord-276260-iccaqz8u	33	15	is	be	VBZ
cord-276260-iccaqz8u	33	16	applied	apply	VBN
cord-276260-iccaqz8u	33	17	.	.	.
cord-276260-iccaqz8u	34	1	ARBs	arb	NNS
cord-276260-iccaqz8u	34	2	block	block	VBP
cord-276260-iccaqz8u	34	3	the	the	DT
cord-276260-iccaqz8u	34	4	AT	AT	NNP
cord-276260-iccaqz8u	34	5	1	1	CD
cord-276260-iccaqz8u	34	6	R	r	NN
cord-276260-iccaqz8u	34	7	and	and	CC
cord-276260-iccaqz8u	34	8	thus	thus	RB
cord-276260-iccaqz8u	34	9	Ang	Ang	NNP
cord-276260-iccaqz8u	34	10	II	II	NNP
cord-276260-iccaqz8u	34	11	can	can	MD
cord-276260-iccaqz8u	34	12	activate	activate	VB
cord-276260-iccaqz8u	34	13	the	the	DT
cord-276260-iccaqz8u	34	14	unopposed	unopposed	JJ
cord-276260-iccaqz8u	34	15	protective	protective	JJ
cord-276260-iccaqz8u	34	16	receptor	receptor	NN
cord-276260-iccaqz8u	34	17	AT	at	IN
cord-276260-iccaqz8u	34	18	2	2	CD
cord-276260-iccaqz8u	34	19	R	r	NN
cord-276260-iccaqz8u	34	20	and	and	CC
cord-276260-iccaqz8u	34	21	further	far	RBR
cord-276260-iccaqz8u	34	22	,	,	,
cord-276260-iccaqz8u	34	23	after	after	IN
cord-276260-iccaqz8u	34	24	ACE2-mediated	ace2-mediated	JJ
cord-276260-iccaqz8u	34	25	conversion	conversion	NN
cord-276260-iccaqz8u	34	26	of	of	IN
cord-276260-iccaqz8u	34	27	Ang	Ang	NNP
cord-276260-iccaqz8u	34	28	II	II	NNP
cord-276260-iccaqz8u	34	29	into	into	IN
cord-276260-iccaqz8u	34	30	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	34	31	-	-	HYPH
cord-276260-iccaqz8u	34	32	7	7	CD
cord-276260-iccaqz8u	34	33	)	)	-RRB-
cord-276260-iccaqz8u	34	34	,	,	,
cord-276260-iccaqz8u	34	35	also	also	RB
cord-276260-iccaqz8u	34	36	the	the	DT
cord-276260-iccaqz8u	34	37	MasR.	masr.	XX
cord-276260-iccaqz8u	35	1	Unfortunately	unfortunately	RB
cord-276260-iccaqz8u	35	2	,	,	,
cord-276260-iccaqz8u	35	3	ARBs	arb	NNS
cord-276260-iccaqz8u	35	4	exert	exert	VBP
cord-276260-iccaqz8u	35	5	only	only	RB
cord-276260-iccaqz8u	35	6	limited	limit	VBN
cord-276260-iccaqz8u	35	7	therapeutic	therapeutic	JJ
cord-276260-iccaqz8u	35	8	effect	effect	NN
cord-276260-iccaqz8u	35	9	in	in	IN
cord-276260-iccaqz8u	35	10	tissue	tissue	NN
cord-276260-iccaqz8u	35	11	injury	injury	NN
cord-276260-iccaqz8u	36	1	(	(	-LRB-
cord-276260-iccaqz8u	36	2	Unger	Unger	NNP
cord-276260-iccaqz8u	36	3	et	et	NNP
cord-276260-iccaqz8u	36	4	al	al	NNP
cord-276260-iccaqz8u	36	5	.	.	NNP
cord-276260-iccaqz8u	36	6	2015	2015	CD
cord-276260-iccaqz8u	36	7	)	)	-RRB-
cord-276260-iccaqz8u	36	8	.	.	.
cord-276260-iccaqz8u	37	1	Moreover	moreover	RB
cord-276260-iccaqz8u	37	2	,	,	,
cord-276260-iccaqz8u	37	3	ARBs	arb	NNS
cord-276260-iccaqz8u	37	4	may	may	MD
cord-276260-iccaqz8u	37	5	reduce	reduce	VB
cord-276260-iccaqz8u	37	6	blood	blood	NN
cord-276260-iccaqz8u	37	7	pressure	pressure	NN
cord-276260-iccaqz8u	37	8	,	,	,
cord-276260-iccaqz8u	37	9	which	which	WDT
cord-276260-iccaqz8u	37	10	in	in	IN
cord-276260-iccaqz8u	37	11	case	case	NN
cord-276260-iccaqz8u	37	12	of	of	IN
cord-276260-iccaqz8u	37	13	critically	critically	RB
cord-276260-iccaqz8u	37	14	ill	ill	JJ
cord-276260-iccaqz8u	37	15	patients	patient	NNS
cord-276260-iccaqz8u	37	16	may	may	MD
cord-276260-iccaqz8u	37	17	lead	lead	VB
cord-276260-iccaqz8u	37	18	to	to	IN
cord-276260-iccaqz8u	37	19	unwanted	unwanted	JJ
cord-276260-iccaqz8u	37	20	hypotension	hypotension	NN
cord-276260-iccaqz8u	37	21	.	.	.
cord-276260-iccaqz8u	38	1	ACEi	ACEi	NNP
cord-276260-iccaqz8u	38	2	block	block	VBP
cord-276260-iccaqz8u	38	3	the	the	DT
cord-276260-iccaqz8u	38	4	ACEmediated	acemediate	VBN
cord-276260-iccaqz8u	38	5	cleavage	cleavage	NN
cord-276260-iccaqz8u	38	6	of	of	IN
cord-276260-iccaqz8u	38	7	Ang	Ang	NNP
cord-276260-iccaqz8u	38	8	I	I	NNP
cord-276260-iccaqz8u	38	9	and	and	CC
cord-276260-iccaqz8u	38	10	thereby	thereby	RB
cord-276260-iccaqz8u	38	11	block	block	VB
cord-276260-iccaqz8u	38	12	the	the	DT
cord-276260-iccaqz8u	38	13	formation	formation	NN
cord-276260-iccaqz8u	38	14	of	of	IN
cord-276260-iccaqz8u	38	15	Ang	Ang	NNP
cord-276260-iccaqz8u	38	16	II	II	NNP
cord-276260-iccaqz8u	38	17	.	.	.
cord-276260-iccaqz8u	39	1	Pros	pro	NNS
cord-276260-iccaqz8u	39	2	and	and	CC
cord-276260-iccaqz8u	39	3	cons	con	NNS
cord-276260-iccaqz8u	39	4	of	of	IN
cord-276260-iccaqz8u	39	5	the	the	DT
cord-276260-iccaqz8u	39	6	use	use	NN
cord-276260-iccaqz8u	39	7	of	of	IN
cord-276260-iccaqz8u	39	8	ARBs	arb	NNS
cord-276260-iccaqz8u	39	9	and	and	CC
cord-276260-iccaqz8u	39	10	ACEi	ACEi	NNS
cord-276260-iccaqz8u	39	11	in	in	IN
cord-276260-iccaqz8u	39	12	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	39	13	have	have	VBP
cord-276260-iccaqz8u	39	14	been	be	VBN
cord-276260-iccaqz8u	39	15	discussed	discuss	VBN
cord-276260-iccaqz8u	40	1	(	(	-LRB-
cord-276260-iccaqz8u	40	2	D'Ardes	D'Ardes	NNP
cord-276260-iccaqz8u	40	3	et	et	FW
cord-276260-iccaqz8u	40	4	al	al	NNP
cord-276260-iccaqz8u	40	5	.	.	NNP
cord-276260-iccaqz8u	40	6	2020	2020	CD
cord-276260-iccaqz8u	40	7	)	)	-RRB-
cord-276260-iccaqz8u	40	8	.	.	.
cord-276260-iccaqz8u	41	1	Continuation	continuation	NN
cord-276260-iccaqz8u	41	2	of	of	IN
cord-276260-iccaqz8u	41	3	the	the	DT
cord-276260-iccaqz8u	41	4	use	use	NN
cord-276260-iccaqz8u	41	5	of	of	IN
cord-276260-iccaqz8u	41	6	an	an	DT
cord-276260-iccaqz8u	41	7	ARB	ARB	NNP
cord-276260-iccaqz8u	41	8	or	or	CC
cord-276260-iccaqz8u	41	9	an	an	DT
cord-276260-iccaqz8u	41	10	ACEi	acei	NN
cord-276260-iccaqz8u	41	11	in	in	IN
cord-276260-iccaqz8u	41	12	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	41	13	has	have	VBZ
cord-276260-iccaqz8u	41	14	been	be	VBN
cord-276260-iccaqz8u	41	15	recommended	recommend	VBN
cord-276260-iccaqz8u	41	16	(	(	-LRB-
cord-276260-iccaqz8u	41	17	Vaduganathan	Vaduganathan	NNP
cord-276260-iccaqz8u	41	18	et	et	FW
cord-276260-iccaqz8u	41	19	al	al	NNP
cord-276260-iccaqz8u	41	20	.	.	NNP
cord-276260-iccaqz8u	41	21	2020	2020	CD
cord-276260-iccaqz8u	41	22	;	;	.
cord-276260-iccaqz8u	42	1	Ingraham	Ingraham	NNP
cord-276260-iccaqz8u	42	2	et	et	NNP
cord-276260-iccaqz8u	42	3	al	al	NNP
cord-276260-iccaqz8u	42	4	.	.	.
cord-276260-iccaqz8u	42	5	2020	2020	CD
cord-276260-iccaqz8u	43	1	;	;	:
cord-276260-iccaqz8u	43	2	Park	Park	NNP
cord-276260-iccaqz8u	43	3	et	et	FW
cord-276260-iccaqz8u	43	4	al	al	NNP
cord-276260-iccaqz8u	43	5	.	.	.
cord-276260-iccaqz8u	43	6	2020	2020	CD
cord-276260-iccaqz8u	44	1	;	;	:
cord-276260-iccaqz8u	44	2	Sanchis	Sanchis	NNP
cord-276260-iccaqz8u	44	3	Gomar	Gomar	NNP
cord-276260-iccaqz8u	44	4	et	et	NNP
cord-276260-iccaqz8u	44	5	al	al	NNP
cord-276260-iccaqz8u	44	6	.	.	NNP
cord-276260-iccaqz8u	44	7	2020	2020	CD
cord-276260-iccaqz8u	44	8	)	)	-RRB-
cord-276260-iccaqz8u	45	1	and	and	CC
cord-276260-iccaqz8u	45	2	has	have	VBZ
cord-276260-iccaqz8u	45	3	been	be	VBN
cord-276260-iccaqz8u	45	4	suggested	suggest	VBN
cord-276260-iccaqz8u	45	5	to	to	TO
cord-276260-iccaqz8u	45	6	be	be	VB
cord-276260-iccaqz8u	45	7	beneficial	beneficial	JJ
cord-276260-iccaqz8u	45	8	in	in	IN
cord-276260-iccaqz8u	45	9	cardiovascular	cardiovascular	JJ
cord-276260-iccaqz8u	45	10	disease	disease	NN
cord-276260-iccaqz8u	46	1	(	(	-LRB-
cord-276260-iccaqz8u	46	2	Wang	Wang	NNP
cord-276260-iccaqz8u	46	3	et	et	NNP
cord-276260-iccaqz8u	46	4	al	al	NNP
cord-276260-iccaqz8u	46	5	.	.	NNP
cord-276260-iccaqz8u	46	6	2020	2020	CD
cord-276260-iccaqz8u	46	7	)	)	-RRB-
cord-276260-iccaqz8u	46	8	.	.	.
cord-276260-iccaqz8u	47	1	Fear	fear	NN
cord-276260-iccaqz8u	47	2	for	for	IN
cord-276260-iccaqz8u	47	3	induction	induction	NN
cord-276260-iccaqz8u	47	4	of	of	IN
cord-276260-iccaqz8u	47	5	upregulation	upregulation	NN
cord-276260-iccaqz8u	47	6	of	of	IN
cord-276260-iccaqz8u	47	7	the	the	DT
cord-276260-iccaqz8u	47	8	CoV-2-receptor	CoV-2-receptor	NNP
cord-276260-iccaqz8u	47	9	ACE2	ACE2	NNP
cord-276260-iccaqz8u	47	10	leading	lead	VBG
cord-276260-iccaqz8u	47	11	to	to	IN
cord-276260-iccaqz8u	47	12	enhanced	enhanced	JJ
cord-276260-iccaqz8u	47	13	infection	infection	NN
cord-276260-iccaqz8u	47	14	(	(	-LRB-
cord-276260-iccaqz8u	47	15	Sommerstein	Sommerstein	NNP
cord-276260-iccaqz8u	47	16	and	and	CC
cord-276260-iccaqz8u	47	17	Gråni	Gråni	NNP
cord-276260-iccaqz8u	47	18	2020	2020	CD
cord-276260-iccaqz8u	47	19	)	)	-RRB-
cord-276260-iccaqz8u	47	20	has	have	VBZ
cord-276260-iccaqz8u	47	21	not	not	RB
cord-276260-iccaqz8u	47	22	been	be	VBN
cord-276260-iccaqz8u	47	23	supported	support	VBN
cord-276260-iccaqz8u	47	24	by	by	IN
cord-276260-iccaqz8u	47	25	clinical	clinical	JJ
cord-276260-iccaqz8u	47	26	data	datum	NNS
cord-276260-iccaqz8u	47	27	(	(	-LRB-
cord-276260-iccaqz8u	47	28	Gupta	Gupta	NNP
cord-276260-iccaqz8u	47	29	and	and	CC
cord-276260-iccaqz8u	47	30	Misra	Misra	NNP
cord-276260-iccaqz8u	47	31	2020	2020	CD
cord-276260-iccaqz8u	47	32	;	;	:
cord-276260-iccaqz8u	47	33	Kai	Kai	NNP
cord-276260-iccaqz8u	47	34	and	and	CC
cord-276260-iccaqz8u	47	35	Kai	Kai	NNP
cord-276260-iccaqz8u	47	36	2020	2020	CD
cord-276260-iccaqz8u	47	37	)	)	-RRB-
cord-276260-iccaqz8u	47	38	.	.	.
cord-276260-iccaqz8u	48	1	In	in	IN
cord-276260-iccaqz8u	48	2	fact	fact	NN
cord-276260-iccaqz8u	48	3	a	a	DT
cord-276260-iccaqz8u	48	4	clinical	clinical	JJ
cord-276260-iccaqz8u	48	5	investigation	investigation	NN
cord-276260-iccaqz8u	48	6	demonstrated	demonstrate	VBD
cord-276260-iccaqz8u	48	7	that	that	IN
cord-276260-iccaqz8u	48	8	no	no	DT
cord-276260-iccaqz8u	48	9	ARB	ARB	NNP
cord-276260-iccaqz8u	48	10	or	or	CC
cord-276260-iccaqz8u	48	11	ACEi	acei	NN
cord-276260-iccaqz8u	48	12	-	-	HYPH
cord-276260-iccaqz8u	48	13	induced	induce	VBN
cord-276260-iccaqz8u	48	14	upregulation	upregulation	NN
cord-276260-iccaqz8u	48	15	of	of	IN
cord-276260-iccaqz8u	48	16	ACE2	ACE2	NNP
cord-276260-iccaqz8u	48	17	takes	take	VBZ
cord-276260-iccaqz8u	48	18	place	place	NN
cord-276260-iccaqz8u	48	19	(	(	-LRB-
cord-276260-iccaqz8u	48	20	Sriram	Sriram	NNP
cord-276260-iccaqz8u	48	21	and	and	CC
cord-276260-iccaqz8u	48	22	Insel	Insel	NNP
cord-276260-iccaqz8u	48	23	2020	2020	CD
cord-276260-iccaqz8u	48	24	)	)	-RRB-
cord-276260-iccaqz8u	48	25	.	.	.
cord-276260-iccaqz8u	49	1	On	on	IN
cord-276260-iccaqz8u	49	2	the	the	DT
cord-276260-iccaqz8u	49	3	other	other	JJ
cord-276260-iccaqz8u	49	4	hand	hand	NN
cord-276260-iccaqz8u	49	5	,	,	,
cord-276260-iccaqz8u	49	6	benefits	benefit	NNS
cord-276260-iccaqz8u	49	7	with	with	IN
cord-276260-iccaqz8u	49	8	respect	respect	NN
cord-276260-iccaqz8u	49	9	to	to	IN
cord-276260-iccaqz8u	49	10	reducing	reduce	VBG
cord-276260-iccaqz8u	49	11	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	49	12	itself	-PRON-	PRP
cord-276260-iccaqz8u	49	13	have	have	VBP
cord-276260-iccaqz8u	49	14	not	not	RB
cord-276260-iccaqz8u	49	15	(	(	-LRB-
cord-276260-iccaqz8u	49	16	yet	yet	RB
cord-276260-iccaqz8u	49	17	)	)	-RRB-
cord-276260-iccaqz8u	49	18	been	be	VBN
cord-276260-iccaqz8u	49	19	demonstrated	demonstrate	VBN
cord-276260-iccaqz8u	49	20	in	in	IN
cord-276260-iccaqz8u	49	21	the	the	DT
cord-276260-iccaqz8u	49	22	clinic	clinic	NN
cord-276260-iccaqz8u	49	23	either	either	CC
cord-276260-iccaqz8u	49	24	(	(	-LRB-
cord-276260-iccaqz8u	49	25	Gupta	Gupta	NNP
cord-276260-iccaqz8u	49	26	and	and	CC
cord-276260-iccaqz8u	49	27	Misra	Misra	NNP
cord-276260-iccaqz8u	49	28	2020	2020	CD
cord-276260-iccaqz8u	49	29	;	;	:
cord-276260-iccaqz8u	49	30	Kai	Kai	NNP
cord-276260-iccaqz8u	49	31	and	and	CC
cord-276260-iccaqz8u	49	32	Kai	Kai	NNP
cord-276260-iccaqz8u	49	33	2020	2020	CD
cord-276260-iccaqz8u	49	34	;	;	:
cord-276260-iccaqz8u	49	35	Rico	Rico	NNP
cord-276260-iccaqz8u	49	36	-	-	HYPH
cord-276260-iccaqz8u	49	37	Mesa	Mesa	NNP
cord-276260-iccaqz8u	49	38	et	et	FW
cord-276260-iccaqz8u	49	39	al	al	NNP
cord-276260-iccaqz8u	49	40	.	.	NNP
cord-276260-iccaqz8u	49	41	2020	2020	CD
cord-276260-iccaqz8u	49	42	)	)	-RRB-
cord-276260-iccaqz8u	49	43	.	.	.
cord-276260-iccaqz8u	50	1	Instead	instead	RB
cord-276260-iccaqz8u	50	2	of	of	IN
cord-276260-iccaqz8u	50	3	blocking	block	VBG
cord-276260-iccaqz8u	50	4	AT	at	IN
cord-276260-iccaqz8u	50	5	1	1	CD
cord-276260-iccaqz8u	50	6	R	r	NN
cord-276260-iccaqz8u	50	7	or	or	CC
cord-276260-iccaqz8u	50	8	inhibiting	inhibit	VBG
cord-276260-iccaqz8u	50	9	ACE	ace	NN
cord-276260-iccaqz8u	50	10	,	,	,
cord-276260-iccaqz8u	50	11	here	here	RB
cord-276260-iccaqz8u	50	12	we	-PRON-	PRP
cord-276260-iccaqz8u	50	13	focus	focus	VBP
cord-276260-iccaqz8u	50	14	on	on	IN
cord-276260-iccaqz8u	50	15	the	the	DT
cord-276260-iccaqz8u	50	16	potential	potential	JJ
cord-276260-iccaqz8u	50	17	benefits	benefit	NNS
cord-276260-iccaqz8u	50	18	in	in	IN
cord-276260-iccaqz8u	50	19	COVID-19	covid-19	CD
cord-276260-iccaqz8u	50	20	of	of	IN
cord-276260-iccaqz8u	50	21	stimulating	stimulate	VBG
cord-276260-iccaqz8u	50	22	the	the	DT
cord-276260-iccaqz8u	50	23	AT	AT	NNP
cord-276260-iccaqz8u	50	24	2	2	CD
cord-276260-iccaqz8u	50	25	R	r	NN
cord-276260-iccaqz8u	50	26	or	or	CC
cord-276260-iccaqz8u	50	27	MasR.	MasR.	NNP
cord-276260-iccaqz8u	50	28	Restoration	restoration	NN
cord-276260-iccaqz8u	50	29	of	of	IN
cord-276260-iccaqz8u	50	30	the	the	DT
cord-276260-iccaqz8u	50	31	balance	balance	NN
cord-276260-iccaqz8u	50	32	in	in	IN
cord-276260-iccaqz8u	50	33	the	the	DT
cord-276260-iccaqz8u	50	34	RAS	RAS	NNP
cord-276260-iccaqz8u	50	35	after	after	IN
cord-276260-iccaqz8u	50	36	corona	corona	NNP
cord-276260-iccaqz8u	50	37	virus	virus	NN
cord-276260-iccaqz8u	50	38	infection	infection	NN
cord-276260-iccaqz8u	50	39	might	may	MD
cord-276260-iccaqz8u	50	40	be	be	VB
cord-276260-iccaqz8u	50	41	pursued	pursue	VBN
cord-276260-iccaqz8u	50	42	by	by	IN
cord-276260-iccaqz8u	50	43	direct	direct	JJ
cord-276260-iccaqz8u	50	44	and	and	CC
cord-276260-iccaqz8u	50	45	specific	specific	JJ
cord-276260-iccaqz8u	50	46	stimulation	stimulation	NN
cord-276260-iccaqz8u	50	47	of	of	IN
cord-276260-iccaqz8u	50	48	the	the	DT
cord-276260-iccaqz8u	50	49	Protective	Protective	NNP
cord-276260-iccaqz8u	50	50	Arm	Arm	NNP
cord-276260-iccaqz8u	50	51	via	via	IN
cord-276260-iccaqz8u	50	52	AT	at	IN
cord-276260-iccaqz8u	50	53	2	2	CD
cord-276260-iccaqz8u	50	54	R	r	NN
cord-276260-iccaqz8u	50	55	or	or	CC
cord-276260-iccaqz8u	50	56	via	via	IN
cord-276260-iccaqz8u	50	57	the	the	DT
cord-276260-iccaqz8u	50	58	ACE2	ACE2	NNP
cord-276260-iccaqz8u	50	59	-Ang-(1	-Ang-(1	:
cord-276260-iccaqz8u	50	60	-	-	SYM
cord-276260-iccaqz8u	50	61	7	7	CD
cord-276260-iccaqz8u	50	62	)	)	-RRB-
cord-276260-iccaqz8u	51	1	-MasR	-MasR	NNP
cord-276260-iccaqz8u	51	2	axis	axis	NN
cord-276260-iccaqz8u	51	3	.	.	.
cord-276260-iccaqz8u	52	1	In	in	IN
cord-276260-iccaqz8u	52	2	a	a	DT
cord-276260-iccaqz8u	52	3	subchronic	subchronic	JJ
cord-276260-iccaqz8u	52	4	lung	lung	NN
cord-276260-iccaqz8u	52	5	injury	injury	NN
cord-276260-iccaqz8u	52	6	model	model	NN
cord-276260-iccaqz8u	52	7	a	a	DT
cord-276260-iccaqz8u	52	8	cyclized	cyclize	VBN
cord-276260-iccaqz8u	52	9	AT	at	IN
cord-276260-iccaqz8u	52	10	2	2	CD
cord-276260-iccaqz8u	52	11	R	r	NN
cord-276260-iccaqz8u	52	12	-	-	HYPH
cord-276260-iccaqz8u	52	13	specific	specific	JJ
cord-276260-iccaqz8u	52	14	peptide	peptide	NN
cord-276260-iccaqz8u	52	15	agonist	agonist	NN
cord-276260-iccaqz8u	52	16	,	,	,
cord-276260-iccaqz8u	52	17	with	with	IN
cord-276260-iccaqz8u	52	18	a	a	DT
cord-276260-iccaqz8u	52	19	half	half	JJ
cord-276260-iccaqz8u	52	20	-	-	HYPH
cord-276260-iccaqz8u	52	21	life	life	NN
cord-276260-iccaqz8u	52	22	of	of	IN
cord-276260-iccaqz8u	52	23	>	>	XX
cord-276260-iccaqz8u	52	24	2	2	CD
cord-276260-iccaqz8u	52	25	h	h	NN
cord-276260-iccaqz8u	52	26	in	in	IN
cord-276260-iccaqz8u	52	27	man	man	NN
cord-276260-iccaqz8u	52	28	,	,	,
cord-276260-iccaqz8u	52	29	reduced	reduce	VBN
cord-276260-iccaqz8u	52	30	inflammation	inflammation	NN
cord-276260-iccaqz8u	52	31	and	and	CC
cord-276260-iccaqz8u	52	32	hypertrophy	hypertrophy	NN
cord-276260-iccaqz8u	53	1	(	(	-LRB-
cord-276260-iccaqz8u	53	2	Wagenaar	Wagenaar	NNP
cord-276260-iccaqz8u	53	3	et	et	NNP
cord-276260-iccaqz8u	53	4	al	al	NNP
cord-276260-iccaqz8u	53	5	.	.	NNP
cord-276260-iccaqz8u	53	6	2013	2013	CD
cord-276260-iccaqz8u	53	7	)	)	-RRB-
cord-276260-iccaqz8u	53	8	.	.	.
cord-276260-iccaqz8u	54	1	In	in	IN
cord-276260-iccaqz8u	54	2	an	an	DT
cord-276260-iccaqz8u	54	3	animal	animal	NN
cord-276260-iccaqz8u	54	4	model	model	NN
cord-276260-iccaqz8u	54	5	of	of	IN
cord-276260-iccaqz8u	54	6	monocrotaline	monocrotaline	NNP
cord-276260-iccaqz8u	54	7	-	-	HYPH
cord-276260-iccaqz8u	54	8	induced	induce	VBN
cord-276260-iccaqz8u	54	9	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	54	10	hypertension	hypertension	NN
cord-276260-iccaqz8u	54	11	,	,	,
cord-276260-iccaqz8u	54	12	a	a	DT
cord-276260-iccaqz8u	54	13	small	small	JJ
cord-276260-iccaqz8u	54	14	molecule	molecule	NN
cord-276260-iccaqz8u	54	15	AT	at	IN
cord-276260-iccaqz8u	55	1	2	2	LS
cord-276260-iccaqz8u	55	2	R	r	NN
cord-276260-iccaqz8u	55	3	agonist	agonist	NN
cord-276260-iccaqz8u	55	4	C21	C21	NNP
cord-276260-iccaqz8u	55	5	reversed	reverse	VBD
cord-276260-iccaqz8u	55	6	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	55	7	fibrosis	fibrosis	NN
cord-276260-iccaqz8u	55	8	and	and	CC
cord-276260-iccaqz8u	55	9	prevented	prevent	VBD
cord-276260-iccaqz8u	55	10	right	right	JJ
cord-276260-iccaqz8u	55	11	ventricular	ventricular	JJ
cord-276260-iccaqz8u	55	12	fibrosis	fibrosis	NN
cord-276260-iccaqz8u	55	13	.	.	.
cord-276260-iccaqz8u	56	1	Furthermore	furthermore	RB
cord-276260-iccaqz8u	56	2	C21	C21	NNP
cord-276260-iccaqz8u	56	3	improved	improve	VBD
cord-276260-iccaqz8u	56	4	right	right	JJ
cord-276260-iccaqz8u	56	5	heart	heart	NN
cord-276260-iccaqz8u	56	6	function	function	NN
cord-276260-iccaqz8u	56	7	,	,	,
cord-276260-iccaqz8u	56	8	decreased	decrease	VBD
cord-276260-iccaqz8u	56	9	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	56	10	vessel	vessel	NN
cord-276260-iccaqz8u	56	11	wall	wall	NN
cord-276260-iccaqz8u	56	12	thickness	thickness	NN
cord-276260-iccaqz8u	56	13	,	,	,
cord-276260-iccaqz8u	56	14	and	and	CC
cord-276260-iccaqz8u	56	15	reduced	reduce	VBN
cord-276260-iccaqz8u	56	16	pro	pro	JJ
cord-276260-iccaqz8u	56	17	-	-	JJ
cord-276260-iccaqz8u	56	18	inflammatory	inflammatory	JJ
cord-276260-iccaqz8u	56	19	cytokines	cytokine	NNS
cord-276260-iccaqz8u	56	20	(	(	-LRB-
cord-276260-iccaqz8u	56	21	Bruce	Bruce	NNP
cord-276260-iccaqz8u	56	22	et	et	NNP
cord-276260-iccaqz8u	56	23	al	al	NNP
cord-276260-iccaqz8u	56	24	.	.	NNP
cord-276260-iccaqz8u	56	25	2015	2015	CD
cord-276260-iccaqz8u	56	26	)	)	-RRB-
cord-276260-iccaqz8u	56	27	.	.	.
cord-276260-iccaqz8u	57	1	In	in	IN
cord-276260-iccaqz8u	57	2	a	a	DT
cord-276260-iccaqz8u	57	3	bleomycin	bleomycin	NN
cord-276260-iccaqz8u	57	4	-	-	HYPH
cord-276260-iccaqz8u	57	5	induced	induce	VBN
cord-276260-iccaqz8u	57	6	lung	lung	NN
cord-276260-iccaqz8u	57	7	injury	injury	NN
cord-276260-iccaqz8u	57	8	model	model	NN
cord-276260-iccaqz8u	57	9	prolonged	prolong	VBN
cord-276260-iccaqz8u	57	10	administration	administration	NN
cord-276260-iccaqz8u	57	11	of	of	IN
cord-276260-iccaqz8u	57	12	the	the	DT
cord-276260-iccaqz8u	57	13	AT	AT	NNP
cord-276260-iccaqz8u	57	14	2	2	CD
cord-276260-iccaqz8u	57	15	R	r	NN
cord-276260-iccaqz8u	57	16	agonist	agonist	NN
cord-276260-iccaqz8u	57	17	C21	C21	NNP
cord-276260-iccaqz8u	57	18	prevented	prevent	VBD
cord-276260-iccaqz8u	57	19	and	and	CC
cord-276260-iccaqz8u	57	20	attenuated	attenuated	JJ
cord-276260-iccaqz8u	57	21	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	57	22	fibrosis	fibrosis	NN
cord-276260-iccaqz8u	57	23	,	,	,
cord-276260-iccaqz8u	57	24	collagen	collagen	NN
cord-276260-iccaqz8u	57	25	deposition	deposition	NN
cord-276260-iccaqz8u	57	26	and	and	CC
cord-276260-iccaqz8u	57	27	lung	lung	NN
cord-276260-iccaqz8u	57	28	remodeling	remodeling	NN
cord-276260-iccaqz8u	57	29	.	.	.
cord-276260-iccaqz8u	58	1	In	in	IN
cord-276260-iccaqz8u	58	2	addition	addition	NN
cord-276260-iccaqz8u	58	3	C21	C21	NNP
cord-276260-iccaqz8u	58	4	reduced	reduce	VBN
cord-276260-iccaqz8u	58	5	inflammation	inflammation	NN
cord-276260-iccaqz8u	58	6	,	,	,
cord-276260-iccaqz8u	58	7	improved	improve	VBN
cord-276260-iccaqz8u	58	8	lung	lung	NN
cord-276260-iccaqz8u	58	9	pressure	pressure	NN
cord-276260-iccaqz8u	58	10	and	and	CC
cord-276260-iccaqz8u	58	11	reduced	reduced	JJ
cord-276260-iccaqz8u	58	12	muscularization	muscularization	NN
cord-276260-iccaqz8u	58	13	of	of	IN
cord-276260-iccaqz8u	58	14	the	the	DT
cord-276260-iccaqz8u	58	15	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	58	16	vessels	vessel	NNS
cord-276260-iccaqz8u	58	17	(	(	-LRB-
cord-276260-iccaqz8u	58	18	Rathinasabapathy	Rathinasabapathy	NNP
cord-276260-iccaqz8u	58	19	et	et	NNP
cord-276260-iccaqz8u	58	20	al	al	NNP
cord-276260-iccaqz8u	58	21	.	.	.
cord-276260-iccaqz8u	58	22	2018	2018	CD
cord-276260-iccaqz8u	58	23	)	)	-RRB-
cord-276260-iccaqz8u	58	24	.	.	.
cord-276260-iccaqz8u	59	1	Currently	currently	RB
cord-276260-iccaqz8u	59	2	the	the	DT
cord-276260-iccaqz8u	59	3	safety	safety	NN
cord-276260-iccaqz8u	59	4	and	and	CC
cord-276260-iccaqz8u	59	5	efficacy	efficacy	NN
cord-276260-iccaqz8u	59	6	of	of	IN
cord-276260-iccaqz8u	59	7	this	this	DT
cord-276260-iccaqz8u	59	8	agonist	agonist	NN
cord-276260-iccaqz8u	59	9	is	be	VBZ
cord-276260-iccaqz8u	59	10	tested	test	VBN
cord-276260-iccaqz8u	59	11	in	in	IN
cord-276260-iccaqz8u	59	12	a	a	DT
cord-276260-iccaqz8u	59	13	Phase	phase	NN
cord-276260-iccaqz8u	59	14	2	2	CD
cord-276260-iccaqz8u	59	15	trial	trial	NN
cord-276260-iccaqz8u	59	16	with	with	IN
cord-276260-iccaqz8u	59	17	patients	patient	NNS
cord-276260-iccaqz8u	59	18	with	with	IN
cord-276260-iccaqz8u	59	19	COVID-19	covid-19	JJ
cord-276260-iccaqz8u	59	20	infection	infection	NN
cord-276260-iccaqz8u	59	21	(	(	-LRB-
cord-276260-iccaqz8u	59	22	ClinicalTrials.gov	ClinicalTrials.gov	NNP
cord-276260-iccaqz8u	59	23	Identifier	identifier	NN
cord-276260-iccaqz8u	59	24	:	:	:
cord-276260-iccaqz8u	59	25	NCT04452435	NCT04452435	NNP
cord-276260-iccaqz8u	59	26	)	)	-RRB-
cord-276260-iccaqz8u	59	27	.	.	.
cord-276260-iccaqz8u	60	1	Recombinant	recombinant	JJ
cord-276260-iccaqz8u	60	2	human	human	JJ
cord-276260-iccaqz8u	60	3	ACE2	ACE2	NNP
cord-276260-iccaqz8u	60	4	,	,	,
cord-276260-iccaqz8u	60	5	which	which	WDT
cord-276260-iccaqz8u	60	6	is	be	VBZ
cord-276260-iccaqz8u	60	7	not	not	RB
cord-276260-iccaqz8u	60	8	membrane	membrane	NN
cord-276260-iccaqz8u	60	9	bound	bind	VBN
cord-276260-iccaqz8u	60	10	,	,	,
cord-276260-iccaqz8u	60	11	still	still	RB
cord-276260-iccaqz8u	60	12	binds	bind	VBZ
cord-276260-iccaqz8u	60	13	to	to	IN
cord-276260-iccaqz8u	60	14	the	the	DT
cord-276260-iccaqz8u	60	15	corona	corona	NN
cord-276260-iccaqz8u	60	16	virus	virus	NN
cord-276260-iccaqz8u	60	17	and	and	CC
cord-276260-iccaqz8u	60	18	thereby	thereby	RB
cord-276260-iccaqz8u	60	19	limits	limit	VBZ
cord-276260-iccaqz8u	60	20	the	the	DT
cord-276260-iccaqz8u	60	21	cell	cell	NN
cord-276260-iccaqz8u	60	22	entry	entry	NN
cord-276260-iccaqz8u	60	23	(	(	-LRB-
cord-276260-iccaqz8u	60	24	Fig	Fig	NNP
cord-276260-iccaqz8u	60	25	.	.	.
cord-276260-iccaqz8u	60	26	1	1	CD
cord-276260-iccaqz8u	60	27	)	)	-RRB-
cord-276260-iccaqz8u	60	28	.	.	.
cord-276260-iccaqz8u	61	1	Furthermore	furthermore	RB
cord-276260-iccaqz8u	61	2	recombinant	recombinant	JJ
cord-276260-iccaqz8u	61	3	ACE2	ACE2	NNP
cord-276260-iccaqz8u	61	4	converts	convert	VBZ
cord-276260-iccaqz8u	61	5	Ang	Ang	NNP
cord-276260-iccaqz8u	61	6	II	II	NNP
cord-276260-iccaqz8u	61	7	into	into	IN
cord-276260-iccaqz8u	61	8	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	61	9	-	-	HYPH
cord-276260-iccaqz8u	61	10	7	7	CD
cord-276260-iccaqz8u	61	11	)	)	-RRB-
cord-276260-iccaqz8u	61	12	.	.	.
cord-276260-iccaqz8u	62	1	In	in	IN
cord-276260-iccaqz8u	62	2	patients	patient	NNS
cord-276260-iccaqz8u	62	3	with	with	IN
cord-276260-iccaqz8u	62	4	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	62	5	arterial	arterial	JJ
cord-276260-iccaqz8u	62	6	hypertension	hypertension	NN
cord-276260-iccaqz8u	62	7	a	a	DT
cord-276260-iccaqz8u	62	8	single	single	JJ
cord-276260-iccaqz8u	62	9	dose	dose	NN
cord-276260-iccaqz8u	62	10	of	of	IN
cord-276260-iccaqz8u	62	11	recombinant	recombinant	JJ
cord-276260-iccaqz8u	62	12	human	human	JJ
cord-276260-iccaqz8u	62	13	ACE2	ACE2	NNP
cord-276260-iccaqz8u	62	14	resulted	result	VBD
cord-276260-iccaqz8u	62	15	in	in	IN
cord-276260-iccaqz8u	62	16	a	a	DT
cord-276260-iccaqz8u	62	17	decreased	decreased	JJ
cord-276260-iccaqz8u	62	18	level	level	NN
cord-276260-iccaqz8u	62	19	of	of	IN
cord-276260-iccaqz8u	62	20	pro	pro	JJ
cord-276260-iccaqz8u	62	21	-	-	JJ
cord-276260-iccaqz8u	62	22	inflammatory	inflammatory	JJ
cord-276260-iccaqz8u	62	23	cytokines	cytokine	NNS
cord-276260-iccaqz8u	62	24	and	and	CC
cord-276260-iccaqz8u	62	25	markers	marker	NNS
cord-276260-iccaqz8u	62	26	of	of	IN
cord-276260-iccaqz8u	62	27	oxidative	oxidative	JJ
cord-276260-iccaqz8u	62	28	stress	stress	NN
cord-276260-iccaqz8u	62	29	accompanied	accompany	VBN
cord-276260-iccaqz8u	62	30	by	by	IN
cord-276260-iccaqz8u	62	31	decreased	decrease	VBN
cord-276260-iccaqz8u	62	32	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	62	33	vascular	vascular	JJ
cord-276260-iccaqz8u	62	34	resistance	resistance	NN
cord-276260-iccaqz8u	62	35	and	and	CC
cord-276260-iccaqz8u	62	36	increased	increase	VBN
cord-276260-iccaqz8u	62	37	cardiac	cardiac	JJ
cord-276260-iccaqz8u	62	38	output	output	NN
cord-276260-iccaqz8u	62	39	(	(	-LRB-
cord-276260-iccaqz8u	62	40	Hemnes	Hemnes	NNP
cord-276260-iccaqz8u	62	41	et	et	NNP
cord-276260-iccaqz8u	62	42	al	al	NNP
cord-276260-iccaqz8u	62	43	.	.	.
cord-276260-iccaqz8u	62	44	2018	2018	CD
cord-276260-iccaqz8u	62	45	)	)	-RRB-
cord-276260-iccaqz8u	62	46	.	.	.
cord-276260-iccaqz8u	63	1	To	to	TO
cord-276260-iccaqz8u	63	2	elucidate	elucidate	VB
cord-276260-iccaqz8u	63	3	the	the	DT
cord-276260-iccaqz8u	63	4	molecular	molecular	JJ
cord-276260-iccaqz8u	63	5	mechanisms	mechanism	NNS
cord-276260-iccaqz8u	63	6	leading	lead	VBG
cord-276260-iccaqz8u	63	7	to	to	IN
cord-276260-iccaqz8u	63	8	the	the	DT
cord-276260-iccaqz8u	63	9	observed	observed	JJ
cord-276260-iccaqz8u	63	10	effects	effect	NNS
cord-276260-iccaqz8u	63	11	,	,	,
cord-276260-iccaqz8u	63	12	RNAseq	RNAseq	NNP
cord-276260-iccaqz8u	63	13	on	on	IN
cord-276260-iccaqz8u	63	14	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	63	15	arteries	artery	NNS
cord-276260-iccaqz8u	63	16	treated	treat	VBN
cord-276260-iccaqz8u	63	17	ex	ex	NN
cord-276260-iccaqz8u	63	18	vivo	vivo	NN
cord-276260-iccaqz8u	63	19	with	with	IN
cord-276260-iccaqz8u	63	20	MasR	MasR	NNP
cord-276260-iccaqz8u	63	21	agonist	agonist	NN
cord-276260-iccaqz8u	63	22	AVE0991	AVE0991	NNP
cord-276260-iccaqz8u	63	23	was	be	VBD
cord-276260-iccaqz8u	63	24	performed	perform	VBN
cord-276260-iccaqz8u	63	25	.	.	.
cord-276260-iccaqz8u	64	1	Significant	significant	JJ
cord-276260-iccaqz8u	64	2	changes	change	NNS
cord-276260-iccaqz8u	64	3	in	in	IN
cord-276260-iccaqz8u	64	4	pressure	pressure	NN
cord-276260-iccaqz8u	64	5	regulation	regulation	NN
cord-276260-iccaqz8u	64	6	,	,	,
cord-276260-iccaqz8u	64	7	inflammatory	inflammatory	JJ
cord-276260-iccaqz8u	64	8	responses	response	NNS
cord-276260-iccaqz8u	64	9	and	and	CC
cord-276260-iccaqz8u	64	10	cell	cell	NN
cord-276260-iccaqz8u	64	11	migration	migration	NN
cord-276260-iccaqz8u	64	12	pathways	pathway	NNS
cord-276260-iccaqz8u	64	13	were	be	VBD
cord-276260-iccaqz8u	64	14	observed	observe	VBN
cord-276260-iccaqz8u	64	15	indicating	indicate	VBG
cord-276260-iccaqz8u	64	16	therapeutic	therapeutic	JJ
cord-276260-iccaqz8u	64	17	effects	effect	NNS
cord-276260-iccaqz8u	64	18	of	of	IN
cord-276260-iccaqz8u	64	19	MasR	MasR	NNP
cord-276260-iccaqz8u	64	20	activation	activation	NN
cord-276260-iccaqz8u	64	21	(	(	-LRB-
cord-276260-iccaqz8u	64	22	Hemnes	Hemnes	NNP
cord-276260-iccaqz8u	64	23	et	et	NNP
cord-276260-iccaqz8u	64	24	al	al	NNP
cord-276260-iccaqz8u	64	25	.	.	.
cord-276260-iccaqz8u	64	26	2018	2018	CD
cord-276260-iccaqz8u	64	27	)	)	-RRB-
cord-276260-iccaqz8u	64	28	.	.	.
cord-276260-iccaqz8u	65	1	Stimulation	stimulation	NN
cord-276260-iccaqz8u	65	2	of	of	IN
cord-276260-iccaqz8u	65	3	the	the	DT
cord-276260-iccaqz8u	65	4	MasR	MasR	NNP
cord-276260-iccaqz8u	65	5	reduces	reduce	VBZ
cord-276260-iccaqz8u	65	6	in	in	IN
cord-276260-iccaqz8u	65	7	vitro	vitro	FW
cord-276260-iccaqz8u	65	8	Ang	Ang	NNP
cord-276260-iccaqz8u	65	9	II	II	NNP
cord-276260-iccaqz8u	65	10	-	-	:
cord-276260-iccaqz8u	65	11	or	or	CC
cord-276260-iccaqz8u	65	12	bleomycin	bleomycin	NN
cord-276260-iccaqz8u	65	13	-	-	HYPH
cord-276260-iccaqz8u	65	14	induced	induce	VBN
cord-276260-iccaqz8u	65	15	apoptosis	apoptosis	NN
cord-276260-iccaqz8u	65	16	of	of	IN
cord-276260-iccaqz8u	65	17	alveolar	alveolar	JJ
cord-276260-iccaqz8u	65	18	epithelial	epithelial	JJ
cord-276260-iccaqz8u	65	19	cells	cell	NNS
cord-276260-iccaqz8u	66	1	(	(	-LRB-
cord-276260-iccaqz8u	66	2	Uhal	Uhal	NNP
cord-276260-iccaqz8u	66	3	et	et	FW
cord-276260-iccaqz8u	66	4	al	al	NNP
cord-276260-iccaqz8u	66	5	.	.	NNP
cord-276260-iccaqz8u	66	6	2011	2011	CD
cord-276260-iccaqz8u	66	7	)	)	-RRB-
cord-276260-iccaqz8u	66	8	.	.	.
cord-276260-iccaqz8u	67	1	A	a	DT
cord-276260-iccaqz8u	67	2	recent	recent	JJ
cord-276260-iccaqz8u	67	3	review	review	NN
cord-276260-iccaqz8u	67	4	speculates	speculate	VBZ
cord-276260-iccaqz8u	67	5	on	on	IN
cord-276260-iccaqz8u	67	6	potential	potential	JJ
cord-276260-iccaqz8u	67	7	benefits	benefit	NNS
cord-276260-iccaqz8u	67	8	of	of	IN
cord-276260-iccaqz8u	67	9	MasR	MasR	NNP
cord-276260-iccaqz8u	67	10	stimulation	stimulation	NN
cord-276260-iccaqz8u	67	11	in	in	IN
cord-276260-iccaqz8u	67	12	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	67	13	based	base	VBN
cord-276260-iccaqz8u	67	14	on	on	IN
cord-276260-iccaqz8u	67	15	data	datum	NNS
cord-276260-iccaqz8u	67	16	obtained	obtain	VBN
cord-276260-iccaqz8u	67	17	from	from	IN
cord-276260-iccaqz8u	67	18	animal	animal	NN
cord-276260-iccaqz8u	67	19	models	model	NNS
cord-276260-iccaqz8u	67	20	of	of	IN
cord-276260-iccaqz8u	67	21	asthma	asthma	NN
cord-276260-iccaqz8u	67	22	,	,	,
cord-276260-iccaqz8u	67	23	lung	lung	NN
cord-276260-iccaqz8u	67	24	fibrosis	fibrosis	NN
cord-276260-iccaqz8u	67	25	,	,	,
cord-276260-iccaqz8u	67	26	ARDS	ARDS	NNP
cord-276260-iccaqz8u	67	27	,	,	,
cord-276260-iccaqz8u	67	28	and	and	CC
cord-276260-iccaqz8u	67	29	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	67	30	emphysema	emphysema	NN
cord-276260-iccaqz8u	67	31	.	.	.
cord-276260-iccaqz8u	68	1	The	the	DT
cord-276260-iccaqz8u	68	2	anti	anti	JJ
cord-276260-iccaqz8u	68	3	-	-	JJ
cord-276260-iccaqz8u	68	4	inflammation	inflammation	JJ
cord-276260-iccaqz8u	68	5	effects	effect	NNS
cord-276260-iccaqz8u	68	6	,	,	,
cord-276260-iccaqz8u	68	7	such	such	JJ
cord-276260-iccaqz8u	68	8	as	as	IN
cord-276260-iccaqz8u	68	9	decreased	decrease	VBN
cord-276260-iccaqz8u	68	10	cytokine	cytokine	NN
cord-276260-iccaqz8u	68	11	and	and	CC
cord-276260-iccaqz8u	68	12	chemokine	chemokine	NN
cord-276260-iccaqz8u	68	13	synthesis	synthesis	NN
cord-276260-iccaqz8u	68	14	,	,	,
cord-276260-iccaqz8u	68	15	migration	migration	NN
cord-276260-iccaqz8u	68	16	of	of	IN
cord-276260-iccaqz8u	68	17	inflammatory	inflammatory	JJ
cord-276260-iccaqz8u	68	18	cells	cell	NNS
cord-276260-iccaqz8u	68	19	to	to	IN
cord-276260-iccaqz8u	68	20	the	the	DT
cord-276260-iccaqz8u	68	21	lung	lung	NN
cord-276260-iccaqz8u	68	22	and	and	CC
cord-276260-iccaqz8u	68	23	the	the	DT
cord-276260-iccaqz8u	68	24	resulting	result	VBG
cord-276260-iccaqz8u	68	25	functional	functional	JJ
cord-276260-iccaqz8u	68	26	improvement	improvement	NN
cord-276260-iccaqz8u	68	27	of	of	IN
cord-276260-iccaqz8u	68	28	the	the	DT
cord-276260-iccaqz8u	68	29	lungs	lung	NNS
cord-276260-iccaqz8u	68	30	would	would	MD
cord-276260-iccaqz8u	68	31	be	be	VB
cord-276260-iccaqz8u	68	32	key	key	JJ
cord-276260-iccaqz8u	68	33	benefits	benefit	NNS
cord-276260-iccaqz8u	68	34	of	of	IN
cord-276260-iccaqz8u	68	35	MasR	MasR	NNP
cord-276260-iccaqz8u	68	36	stimulation	stimulation	NN
cord-276260-iccaqz8u	68	37	(	(	-LRB-
cord-276260-iccaqz8u	68	38	Fig	fig	NN
cord-276260-iccaqz8u	68	39	.	.	NNP
cord-276260-iccaqz8u	68	40	2	2	CD
cord-276260-iccaqz8u	68	41	)	)	-RRB-
cord-276260-iccaqz8u	68	42	.	.	.
cord-276260-iccaqz8u	69	1	In	in	IN
cord-276260-iccaqz8u	69	2	addition	addition	NN
cord-276260-iccaqz8u	69	3	,	,	,
cord-276260-iccaqz8u	69	4	prolonged	prolong	VBN
cord-276260-iccaqz8u	69	5	treatment	treatment	NN
cord-276260-iccaqz8u	69	6	might	may	MD
cord-276260-iccaqz8u	69	7	Fig	fig	NN
cord-276260-iccaqz8u	69	8	.	.	.
cord-276260-iccaqz8u	69	9	2	2	CD
cord-276260-iccaqz8u	69	10	Anti	anti	JJ
cord-276260-iccaqz8u	69	11	-	-	JJ
cord-276260-iccaqz8u	69	12	inflammatory	inflammatory	JJ
cord-276260-iccaqz8u	69	13	and	and	CC
cord-276260-iccaqz8u	69	14	anti	anti	JJ
cord-276260-iccaqz8u	69	15	-	-	JJ
cord-276260-iccaqz8u	69	16	fibrotic	fibrotic	JJ
cord-276260-iccaqz8u	69	17	pathways	pathway	NNS
cord-276260-iccaqz8u	69	18	mediated	mediate	VBN
cord-276260-iccaqz8u	69	19	by	by	IN
cord-276260-iccaqz8u	69	20	activated	activate	VBN
cord-276260-iccaqz8u	69	21	AT	at	IN
cord-276260-iccaqz8u	69	22	2	2	CD
cord-276260-iccaqz8u	69	23	R	r	NN
cord-276260-iccaqz8u	69	24	and/or	and/or	CC
cord-276260-iccaqz8u	69	25	MasR.	MasR.	NNP
cord-276260-iccaqz8u	70	1	The	the	DT
cord-276260-iccaqz8u	70	2	AT	AT	NNP
cord-276260-iccaqz8u	70	3	2	2	CD
cord-276260-iccaqz8u	70	4	R	r	NN
cord-276260-iccaqz8u	70	5	and	and	CC
cord-276260-iccaqz8u	70	6	MasR	MasR	NNP
cord-276260-iccaqz8u	70	7	are	be	VBP
cord-276260-iccaqz8u	70	8	expressed	express	VBN
cord-276260-iccaqz8u	70	9	in	in	IN
cord-276260-iccaqz8u	70	10	the	the	DT
cord-276260-iccaqz8u	70	11	cell	cell	NN
cord-276260-iccaqz8u	70	12	as	as	IN
cord-276260-iccaqz8u	70	13	monomers	monomer	NNS
cord-276260-iccaqz8u	70	14	,	,	,
cord-276260-iccaqz8u	70	15	homodimers	homodimer	NNS
cord-276260-iccaqz8u	70	16	and	and	CC
cord-276260-iccaqz8u	70	17	AT	AT	NNP
cord-276260-iccaqz8u	70	18	2	2	CD
cord-276260-iccaqz8u	70	19	R	R	NNP
cord-276260-iccaqz8u	70	20	-	-	HYPH
cord-276260-iccaqz8u	70	21	MasR	MasR	NNP
cord-276260-iccaqz8u	70	22	heterodimers	heterodimer	NNS
cord-276260-iccaqz8u	70	23	(	(	-LRB-
cord-276260-iccaqz8u	70	24	Leonhardt	Leonhardt	NNP
cord-276260-iccaqz8u	70	25	et	et	FW
cord-276260-iccaqz8u	70	26	al	al	NNP
cord-276260-iccaqz8u	70	27	.	.	.
cord-276260-iccaqz8u	70	28	2017	2017	CD
cord-276260-iccaqz8u	70	29	)	)	-RRB-
cord-276260-iccaqz8u	70	30	and	and	CC
cord-276260-iccaqz8u	70	31	their	-PRON-	PRP$
cord-276260-iccaqz8u	70	32	downstream	downstream	JJ
cord-276260-iccaqz8u	70	33	pathways	pathway	NNS
cord-276260-iccaqz8u	70	34	are	be	VBP
cord-276260-iccaqz8u	70	35	largely	largely	RB
cord-276260-iccaqz8u	70	36	similar	similar	JJ
cord-276260-iccaqz8u	70	37	,	,	,
cord-276260-iccaqz8u	70	38	making	make	VBG
cord-276260-iccaqz8u	70	39	it	-PRON-	PRP
cord-276260-iccaqz8u	70	40	often	often	RB
cord-276260-iccaqz8u	70	41	impossible	impossible	JJ
cord-276260-iccaqz8u	70	42	to	to	TO
cord-276260-iccaqz8u	70	43	distinguish	distinguish	VB
cord-276260-iccaqz8u	70	44	between	between	IN
cord-276260-iccaqz8u	70	45	them	-PRON-	PRP
cord-276260-iccaqz8u	70	46	.	.	.
cord-276260-iccaqz8u	71	1	During	during	IN
cord-276260-iccaqz8u	71	2	infection	infection	NN
cord-276260-iccaqz8u	71	3	the	the	DT
cord-276260-iccaqz8u	71	4	AT	at	NN
cord-276260-iccaqz8u	71	5	1	1	CD
cord-276260-iccaqz8u	71	6	R	r	NN
cord-276260-iccaqz8u	71	7	becomes	become	VBZ
cord-276260-iccaqz8u	71	8	activated	activate	VBN
cord-276260-iccaqz8u	71	9	initiating	initiate	VBG
cord-276260-iccaqz8u	71	10	inflammatory	inflammatory	JJ
cord-276260-iccaqz8u	71	11	processes	process	NNS
cord-276260-iccaqz8u	71	12	via	via	IN
cord-276260-iccaqz8u	71	13	NFκB	NFκB	NNP
cord-276260-iccaqz8u	71	14	and	and	CC
cord-276260-iccaqz8u	71	15	MAPK	MAPK	NNP
cord-276260-iccaqz8u	71	16	.	.	.
cord-276260-iccaqz8u	72	1	Prolonged	prolonged	JJ
cord-276260-iccaqz8u	72	2	activation	activation	NN
cord-276260-iccaqz8u	72	3	of	of	IN
cord-276260-iccaqz8u	72	4	AT	at	NN
cord-276260-iccaqz8u	72	5	1	1	CD
cord-276260-iccaqz8u	72	6	R	r	NN
cord-276260-iccaqz8u	72	7	may	may	MD
cord-276260-iccaqz8u	72	8	initiate	initiate	VB
cord-276260-iccaqz8u	72	9	pro	pro	JJ
cord-276260-iccaqz8u	72	10	-	-	JJ
cord-276260-iccaqz8u	72	11	fibrotic	fibrotic	JJ
cord-276260-iccaqz8u	72	12	processes	process	NNS
cord-276260-iccaqz8u	72	13	with	with	IN
cord-276260-iccaqz8u	72	14	TGFβ	TGFβ	NNS
cord-276260-iccaqz8u	72	15	as	as	IN
cord-276260-iccaqz8u	72	16	a	a	DT
cord-276260-iccaqz8u	72	17	key	key	JJ
cord-276260-iccaqz8u	72	18	molecule	molecule	NN
cord-276260-iccaqz8u	72	19	.	.	.
cord-276260-iccaqz8u	73	1	Agonist	agonist	NN
cord-276260-iccaqz8u	73	2	-	-	HYPH
cord-276260-iccaqz8u	73	3	mediated	mediate	VBN
cord-276260-iccaqz8u	73	4	stimulation	stimulation	NN
cord-276260-iccaqz8u	73	5	of	of	IN
cord-276260-iccaqz8u	73	6	AT	AT	NNP
cord-276260-iccaqz8u	73	7	2	2	CD
cord-276260-iccaqz8u	73	8	R	r	NN
cord-276260-iccaqz8u	73	9	or	or	CC
cord-276260-iccaqz8u	73	10	MasR	MasR	NNP
cord-276260-iccaqz8u	73	11	inhibits	inhibit	VBZ
cord-276260-iccaqz8u	73	12	activation	activation	NN
cord-276260-iccaqz8u	73	13	of	of	IN
cord-276260-iccaqz8u	73	14	NFκB	NFκB	NNP
cord-276260-iccaqz8u	73	15	and	and	CC
cord-276260-iccaqz8u	73	16	MAPK	MAPK	NNP
cord-276260-iccaqz8u	73	17	resulting	result	VBG
cord-276260-iccaqz8u	73	18	in	in	IN
cord-276260-iccaqz8u	73	19	anti	anti	JJ
cord-276260-iccaqz8u	73	20	-	-	JJ
cord-276260-iccaqz8u	73	21	inflammation	inflammation	NN
cord-276260-iccaqz8u	73	22	.	.	.
cord-276260-iccaqz8u	74	1	For	for	IN
cord-276260-iccaqz8u	74	2	the	the	DT
cord-276260-iccaqz8u	74	3	anti	anti	JJ
cord-276260-iccaqz8u	74	4	-	-	JJ
cord-276260-iccaqz8u	74	5	fibrotic	fibrotic	JJ
cord-276260-iccaqz8u	74	6	action	action	NN
cord-276260-iccaqz8u	74	7	the	the	DT
cord-276260-iccaqz8u	74	8	inhibition	inhibition	NN
cord-276260-iccaqz8u	74	9	of	of	IN
cord-276260-iccaqz8u	74	10	receptor	receptor	NN
cord-276260-iccaqz8u	74	11	tyrosine	tyrosine	NN
cord-276260-iccaqz8u	74	12	kinase	kinase	NN
cord-276260-iccaqz8u	74	13	activity	activity	NN
cord-276260-iccaqz8u	74	14	by	by	IN
cord-276260-iccaqz8u	74	15	dephosphorylation	dephosphorylation	NN
cord-276260-iccaqz8u	74	16	on	on	IN
cord-276260-iccaqz8u	74	17	the	the	DT
cord-276260-iccaqz8u	74	18	one	one	CD
cord-276260-iccaqz8u	74	19	hand	hand	NN
cord-276260-iccaqz8u	74	20	,	,	,
cord-276260-iccaqz8u	74	21	and	and	CC
cord-276260-iccaqz8u	74	22	activation	activation	NN
cord-276260-iccaqz8u	74	23	of	of	IN
cord-276260-iccaqz8u	74	24	cGMP	cGMP	NNP
cord-276260-iccaqz8u	74	25	on	on	IN
cord-276260-iccaqz8u	74	26	the	the	DT
cord-276260-iccaqz8u	74	27	other	other	JJ
cord-276260-iccaqz8u	74	28	hand	hand	NN
cord-276260-iccaqz8u	74	29	,	,	,
cord-276260-iccaqz8u	74	30	plays	play	VBZ
cord-276260-iccaqz8u	74	31	a	a	DT
cord-276260-iccaqz8u	74	32	crucial	crucial	JJ
cord-276260-iccaqz8u	74	33	role	role	NN
cord-276260-iccaqz8u	74	34	.	.	.
cord-276260-iccaqz8u	75	1	In	in	IN
cord-276260-iccaqz8u	75	2	addition	addition	NN
cord-276260-iccaqz8u	75	3	,	,	,
cord-276260-iccaqz8u	75	4	heterodimerization	heterodimerization	NN
cord-276260-iccaqz8u	75	5	between	between	IN
cord-276260-iccaqz8u	75	6	AT	AT	NNP
cord-276260-iccaqz8u	75	7	1	1	CD
cord-276260-iccaqz8u	75	8	R	r	NN
cord-276260-iccaqz8u	75	9	and	and	CC
cord-276260-iccaqz8u	75	10	AT	at	NN
cord-276260-iccaqz8u	75	11	2	2	CD
cord-276260-iccaqz8u	75	12	R	r	NN
cord-276260-iccaqz8u	75	13	or	or	CC
cord-276260-iccaqz8u	75	14	MasR	MasR	NNP
cord-276260-iccaqz8u	75	15	inhibits	inhibit	VBZ
cord-276260-iccaqz8u	75	16	detrimental	detrimental	JJ
cord-276260-iccaqz8u	75	17	effects	effect	NNS
cord-276260-iccaqz8u	75	18	mediated	mediate	VBN
cord-276260-iccaqz8u	75	19	by	by	IN
cord-276260-iccaqz8u	75	20	AT	AT	NNP
cord-276260-iccaqz8u	75	21	1	1	CD
cord-276260-iccaqz8u	75	22	R.	R.	NNP
cord-276260-iccaqz8u	75	23	Blue	Blue	NNP
cord-276260-iccaqz8u	75	24	lines	line	NNS
cord-276260-iccaqz8u	75	25	:	:	:
cord-276260-iccaqz8u	75	26	pro	pro	JJ
cord-276260-iccaqz8u	75	27	-	-	JJ
cord-276260-iccaqz8u	75	28	fibrotic	fibrotic	JJ
cord-276260-iccaqz8u	75	29	pathways	pathway	NNS
cord-276260-iccaqz8u	75	30	;	;	:
cord-276260-iccaqz8u	75	31	red	red	JJ
cord-276260-iccaqz8u	75	32	lines	line	NNS
cord-276260-iccaqz8u	75	33	:	:	:
cord-276260-iccaqz8u	75	34	pro	pro	JJ
cord-276260-iccaqz8u	75	35	-	-	JJ
cord-276260-iccaqz8u	75	36	inflammatory	inflammatory	JJ
cord-276260-iccaqz8u	75	37	pathways	pathway	NNS
cord-276260-iccaqz8u	75	38	;	;	:
cord-276260-iccaqz8u	75	39	green	green	JJ
cord-276260-iccaqz8u	75	40	lines	line	NNS
cord-276260-iccaqz8u	75	41	:	:	:
cord-276260-iccaqz8u	75	42	anti	anti	JJ
cord-276260-iccaqz8u	75	43	-	-	JJ
cord-276260-iccaqz8u	75	44	inflammatory	inflammatory	JJ
cord-276260-iccaqz8u	75	45	or	or	CC
cord-276260-iccaqz8u	75	46	antifibrotic	antifibrotic	JJ
cord-276260-iccaqz8u	75	47	pathways	pathway	NNS
cord-276260-iccaqz8u	75	48	.	.	.
cord-276260-iccaqz8u	76	1	AT	at	IN
cord-276260-iccaqz8u	76	2	2	2	CD
cord-276260-iccaqz8u	77	1	R	R	NNP
cord-276260-iccaqz8u	77	2	/	/	SYM
cord-276260-iccaqz8u	77	3	MasR	MasR	NNP
cord-276260-iccaqz8u	77	4	:	:	:
cord-276260-iccaqz8u	78	1	angiotensin	angiotensin	NNP
cord-276260-iccaqz8u	78	2	II	II	NNP
cord-276260-iccaqz8u	78	3	type	type	NN
cord-276260-iccaqz8u	78	4	2	2	CD
cord-276260-iccaqz8u	78	5	receptor	receptor	NN
cord-276260-iccaqz8u	78	6	or	or	CC
cord-276260-iccaqz8u	78	7	Mas	Mas	NNP
cord-276260-iccaqz8u	78	8	receptor	receptor	NN
cord-276260-iccaqz8u	78	9	or	or	CC
cord-276260-iccaqz8u	78	10	AT	at	IN
cord-276260-iccaqz8u	78	11	2	2	CD
cord-276260-iccaqz8u	78	12	R	R	NNP
cord-276260-iccaqz8u	78	13	-	-	HYPH
cord-276260-iccaqz8u	78	14	MasR	MasR	NNP
cord-276260-iccaqz8u	78	15	heterodimers	heterodimer	NNS
cord-276260-iccaqz8u	78	16	;	;	:
cord-276260-iccaqz8u	78	17	TGFBR2	TGFBR2	NNP
cord-276260-iccaqz8u	78	18	:	:	:
cord-276260-iccaqz8u	79	1	transforming	transform	VBG
cord-276260-iccaqz8u	79	2	growth	growth	NN
cord-276260-iccaqz8u	79	3	factor	factor	NN
cord-276260-iccaqz8u	79	4	beta	beta	NN
cord-276260-iccaqz8u	79	5	receptor	receptor	NN
cord-276260-iccaqz8u	79	6	II	II	NNP
cord-276260-iccaqz8u	79	7	;	;	:
cord-276260-iccaqz8u	80	1	AT	at	IN
cord-276260-iccaqz8u	80	2	1	1	CD
cord-276260-iccaqz8u	80	3	R	r	NN
cord-276260-iccaqz8u	80	4	:	:	:
cord-276260-iccaqz8u	80	5	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	80	6	II	II	NNP
cord-276260-iccaqz8u	80	7	type	type	NN
cord-276260-iccaqz8u	80	8	1	1	CD
cord-276260-iccaqz8u	80	9	receptor	receptor	NN
cord-276260-iccaqz8u	80	10	;	;	:
cord-276260-iccaqz8u	80	11	RTKs	RTKs	NNP
cord-276260-iccaqz8u	80	12	:	:	:
cord-276260-iccaqz8u	80	13	receptor	receptor	NN
cord-276260-iccaqz8u	80	14	tyrosine	tyrosine	NN
cord-276260-iccaqz8u	80	15	kinases	kinase	NNS
cord-276260-iccaqz8u	80	16	;	;	:
cord-276260-iccaqz8u	81	1	Akt	Akt	NNP
cord-276260-iccaqz8u	81	2	:	:	:
cord-276260-iccaqz8u	81	3	protein	protein	NN
cord-276260-iccaqz8u	81	4	kinase	kinase	NN
cord-276260-iccaqz8u	81	5	B	b	NN
cord-276260-iccaqz8u	81	6	;	;	:
cord-276260-iccaqz8u	81	7	PTP	ptp	NN
cord-276260-iccaqz8u	81	8	:	:	:
cord-276260-iccaqz8u	81	9	protein	protein	NN
cord-276260-iccaqz8u	81	10	tyrosine	tyrosine	NN
cord-276260-iccaqz8u	81	11	phosphatase	phosphatase	NN
cord-276260-iccaqz8u	81	12	;	;	:
cord-276260-iccaqz8u	81	13	PSP	PSP	NNP
cord-276260-iccaqz8u	81	14	:	:	:
cord-276260-iccaqz8u	81	15	protein	protein	NN
cord-276260-iccaqz8u	81	16	serine	serine	NN
cord-276260-iccaqz8u	81	17	/	/	SYM
cord-276260-iccaqz8u	81	18	threonine	threonine	NN
cord-276260-iccaqz8u	81	19	phosphatase	phosphatase	NN
cord-276260-iccaqz8u	81	20	;	;	:
cord-276260-iccaqz8u	81	21	eNOS	enos	JJ
cord-276260-iccaqz8u	81	22	:	:	:
cord-276260-iccaqz8u	81	23	nitric	nitric	JJ
cord-276260-iccaqz8u	81	24	oxide	oxide	NN
cord-276260-iccaqz8u	81	25	synthase	synthase	NN
cord-276260-iccaqz8u	81	26	3	3	CD
cord-276260-iccaqz8u	81	27	;	;	.
cord-276260-iccaqz8u	82	1	NO	no	RB
cord-276260-iccaqz8u	82	2	:	:	:
cord-276260-iccaqz8u	82	3	nitric	nitric	NN
cord-276260-iccaqz8u	82	4	oxide	oxide	NN
cord-276260-iccaqz8u	82	5	;	;	:
cord-276260-iccaqz8u	82	6	cGMP	cgmp	JJ
cord-276260-iccaqz8u	82	7	:	:	:
cord-276260-iccaqz8u	82	8	cyclic	cyclic	JJ
cord-276260-iccaqz8u	82	9	guanosine	guanosine	NN
cord-276260-iccaqz8u	82	10	monophosphate	monophosphate	NN
cord-276260-iccaqz8u	82	11	;	;	:
cord-276260-iccaqz8u	82	12	MMP9	mmp9	NN
cord-276260-iccaqz8u	82	13	:	:	:
cord-276260-iccaqz8u	82	14	matrix	matrix	NNP
cord-276260-iccaqz8u	82	15	metallopeptidase	metallopeptidase	NNP
cord-276260-iccaqz8u	82	16	9	9	CD
cord-276260-iccaqz8u	82	17	;	;	:
cord-276260-iccaqz8u	82	18	TGFβ	TGFβ	NNP
cord-276260-iccaqz8u	82	19	:	:	:
cord-276260-iccaqz8u	83	1	transforming	transform	VBG
cord-276260-iccaqz8u	83	2	growth	growth	NN
cord-276260-iccaqz8u	83	3	factor	factor	NN
cord-276260-iccaqz8u	83	4	beta	beta	NN
cord-276260-iccaqz8u	83	5	;	;	:
cord-276260-iccaqz8u	83	6	PDGF	pdgf	NN
cord-276260-iccaqz8u	83	7	:	:	:
cord-276260-iccaqz8u	84	1	platelet	platelet	NN
cord-276260-iccaqz8u	84	2	-	-	HYPH
cord-276260-iccaqz8u	84	3	derived	derive	VBN
cord-276260-iccaqz8u	84	4	growth	growth	NN
cord-276260-iccaqz8u	84	5	factor	factor	NN
cord-276260-iccaqz8u	84	6	;	;	:
cord-276260-iccaqz8u	84	7	FGF	fgf	NN
cord-276260-iccaqz8u	84	8	:	:	:
cord-276260-iccaqz8u	84	9	fibroblast	fibroblast	NN
cord-276260-iccaqz8u	84	10	growth	growth	NN
cord-276260-iccaqz8u	84	11	factor	factor	NN
cord-276260-iccaqz8u	84	12	;	;	:
cord-276260-iccaqz8u	84	13	CTGF	ctgf	NN
cord-276260-iccaqz8u	84	14	:	:	:
cord-276260-iccaqz8u	84	15	connective	connective	JJ
cord-276260-iccaqz8u	84	16	tissue	tissue	NN
cord-276260-iccaqz8u	84	17	growth	growth	NN
cord-276260-iccaqz8u	84	18	factor	factor	NN
cord-276260-iccaqz8u	84	19	;	;	:
cord-276260-iccaqz8u	84	20	VEGF	VEGF	NNP
cord-276260-iccaqz8u	84	21	:	:	:
cord-276260-iccaqz8u	84	22	vascular	vascular	JJ
cord-276260-iccaqz8u	84	23	endothelial	endothelial	JJ
cord-276260-iccaqz8u	84	24	growth	growth	NN
cord-276260-iccaqz8u	84	25	factor	factor	NN
cord-276260-iccaqz8u	84	26	;	;	:
cord-276260-iccaqz8u	84	27	ECM	ECM	NNP
cord-276260-iccaqz8u	84	28	:	:	:
cord-276260-iccaqz8u	84	29	extracellular	extracellular	JJ
cord-276260-iccaqz8u	84	30	matrix	matrix	NN
cord-276260-iccaqz8u	84	31	;	;	:
cord-276260-iccaqz8u	84	32	ERK	erk	NN
cord-276260-iccaqz8u	84	33	:	:	:
cord-276260-iccaqz8u	84	34	extracellular	extracellular	JJ
cord-276260-iccaqz8u	84	35	signal	signal	NN
cord-276260-iccaqz8u	84	36	-	-	HYPH
cord-276260-iccaqz8u	84	37	regulated	regulate	VBN
cord-276260-iccaqz8u	84	38	kinases	kinase	NNS
cord-276260-iccaqz8u	84	39	;	;	:
cord-276260-iccaqz8u	84	40	MAPK	MAPK	NNP
cord-276260-iccaqz8u	84	41	:	:	:
cord-276260-iccaqz8u	85	1	mitogen	mitogen	NNP
cord-276260-iccaqz8u	85	2	-	-	HYPH
cord-276260-iccaqz8u	85	3	activated	activate	VBN
cord-276260-iccaqz8u	85	4	protein	protein	NN
cord-276260-iccaqz8u	85	5	kinase	kinase	NN
cord-276260-iccaqz8u	85	6	;	;	:
cord-276260-iccaqz8u	85	7	NOX	NOX	NNP
cord-276260-iccaqz8u	85	8	:	:	:
cord-276260-iccaqz8u	85	9	NADPH	NADPH	NNP
cord-276260-iccaqz8u	85	10	oxidase	oxidase	NN
cord-276260-iccaqz8u	85	11	;	;	:
cord-276260-iccaqz8u	85	12	ROS	ROS	NNP
cord-276260-iccaqz8u	85	13	:	:	:
cord-276260-iccaqz8u	85	14	reactive	reactive	JJ
cord-276260-iccaqz8u	85	15	oxygen	oxygen	NN
cord-276260-iccaqz8u	85	16	species	specie	NNS
cord-276260-iccaqz8u	85	17	;	;	:
cord-276260-iccaqz8u	86	1	NFκB	nfκb	JJ
cord-276260-iccaqz8u	86	2	:	:	:
cord-276260-iccaqz8u	86	3	nuclear	nuclear	JJ
cord-276260-iccaqz8u	86	4	factor	factor	NN
cord-276260-iccaqz8u	86	5	kappa	kappa	NN
cord-276260-iccaqz8u	86	6	B	B	NNP
cord-276260-iccaqz8u	86	7	;	;	:
cord-276260-iccaqz8u	87	1	Gαi	Gαi	NNP
cord-276260-iccaqz8u	87	2	:	:	:
cord-276260-iccaqz8u	87	3	G	g	NN
cord-276260-iccaqz8u	87	4	protein	protein	NN
cord-276260-iccaqz8u	87	5	alpha	alpha	NN
cord-276260-iccaqz8u	87	6	i	i	NNP
cord-276260-iccaqz8u	87	7	subunit	subunit	NN
cord-276260-iccaqz8u	87	8	;	;	.
cord-276260-iccaqz8u	88	1	ATIP	ATIP	NNP
cord-276260-iccaqz8u	88	2	:	:	:
cord-276260-iccaqz8u	89	1	AT	at	IN
cord-276260-iccaqz8u	89	2	2	2	CD
cord-276260-iccaqz8u	89	3	R	r	NN
cord-276260-iccaqz8u	89	4	-	-	HYPH
cord-276260-iccaqz8u	89	5	interacting	interact	VBG
cord-276260-iccaqz8u	89	6	proteins	protein	NNS
cord-276260-iccaqz8u	89	7	/	/	SYM
cord-276260-iccaqz8u	89	8	microtubuleassociated	microtubuleassociate	VBN
cord-276260-iccaqz8u	89	9	scaffold	scaffold	NN
cord-276260-iccaqz8u	89	10	proteins	protein	NNS
cord-276260-iccaqz8u	89	11	;	;	:
cord-276260-iccaqz8u	89	12	PP2A	PP2A	NNS
cord-276260-iccaqz8u	89	13	:	:	:
cord-276260-iccaqz8u	89	14	protein	protein	NN
cord-276260-iccaqz8u	89	15	phosphatase	phosphatase	NN
cord-276260-iccaqz8u	89	16	2A	2a	CD
cord-276260-iccaqz8u	89	17	;	;	:
cord-276260-iccaqz8u	89	18	SHP-1	shp-1	NN
cord-276260-iccaqz8u	89	19	:	:	:
cord-276260-iccaqz8u	90	1	Src	Src	NNP
cord-276260-iccaqz8u	90	2	homology	homology	NN
cord-276260-iccaqz8u	90	3	region	region	NN
cord-276260-iccaqz8u	90	4	2	2	CD
cord-276260-iccaqz8u	90	5	domain	domain	NN
cord-276260-iccaqz8u	90	6	-	-	HYPH
cord-276260-iccaqz8u	90	7	containing	contain	VBG
cord-276260-iccaqz8u	90	8	phosphatase-1	phosphatase-1	NN
cord-276260-iccaqz8u	90	9	;	;	.
cord-276260-iccaqz8u	91	1	MKP-1	MKP-1	NNP
cord-276260-iccaqz8u	91	2	:	:	:
cord-276260-iccaqz8u	92	1	MAPK	MAPK	NNP
cord-276260-iccaqz8u	92	2	Phosphatase	Phosphatase	NNP
cord-276260-iccaqz8u	92	3	1	1	CD
cord-276260-iccaqz8u	92	4	.	.	.
cord-276260-iccaqz8u	93	1	The	the	DT
cord-276260-iccaqz8u	93	2	pathways	pathway	NNS
cord-276260-iccaqz8u	93	3	are	be	VBP
cord-276260-iccaqz8u	93	4	based	base	VBN
cord-276260-iccaqz8u	93	5	on	on	IN
cord-276260-iccaqz8u	93	6	:	:	:
cord-276260-iccaqz8u	93	7	Unger	Unger	NNP
cord-276260-iccaqz8u	93	8	et	et	NNP
cord-276260-iccaqz8u	93	9	al	al	NNP
cord-276260-iccaqz8u	93	10	.	.	.
cord-276260-iccaqz8u	93	11	2015	2015	CD
cord-276260-iccaqz8u	93	12	;	;	:
cord-276260-iccaqz8u	93	13	Sumners	Sumners	NNP
cord-276260-iccaqz8u	93	14	et	et	NNP
cord-276260-iccaqz8u	93	15	al	al	NNP
cord-276260-iccaqz8u	93	16	.	.	.
cord-276260-iccaqz8u	94	1	2019	2019	CD
cord-276260-iccaqz8u	94	2	;	;	:
cord-276260-iccaqz8u	94	3	Zhang	Zhang	NNP
cord-276260-iccaqz8u	94	4	et	et	NNP
cord-276260-iccaqz8u	94	5	al	al	NNP
cord-276260-iccaqz8u	94	6	.	.	.
cord-276260-iccaqz8u	95	1	2014	2014	CD
cord-276260-iccaqz8u	95	2	;	;	:
cord-276260-iccaqz8u	95	3	Leonhardt	Leonhardt	NNP
cord-276260-iccaqz8u	95	4	et	et	FW
cord-276260-iccaqz8u	95	5	al	al	NNP
cord-276260-iccaqz8u	95	6	.	.	.
cord-276260-iccaqz8u	95	7	2017	2017	CD
cord-276260-iccaqz8u	95	8	;	;	:
cord-276260-iccaqz8u	95	9	Chappell	Chappell	NNP
cord-276260-iccaqz8u	95	10	and	and	CC
cord-276260-iccaqz8u	95	11	Al	Al	NNP
cord-276260-iccaqz8u	95	12	Zayadneh	Zayadneh	NNP
cord-276260-iccaqz8u	95	13	2017	2017	CD
cord-276260-iccaqz8u	95	14	result	result	NN
cord-276260-iccaqz8u	95	15	in	in	IN
cord-276260-iccaqz8u	95	16	anti	anti	JJ
cord-276260-iccaqz8u	95	17	-	-	JJ
cord-276260-iccaqz8u	95	18	fibrotic	fibrotic	JJ
cord-276260-iccaqz8u	95	19	effects	effect	NNS
cord-276260-iccaqz8u	95	20	in	in	IN
cord-276260-iccaqz8u	95	21	lung	lung	NN
cord-276260-iccaqz8u	95	22	tissue	tissue	NN
cord-276260-iccaqz8u	96	1	(	(	-LRB-
cord-276260-iccaqz8u	96	2	Magalhaes	Magalhaes	NNPS
cord-276260-iccaqz8u	96	3	et	et	NNP
cord-276260-iccaqz8u	96	4	al	al	NNP
cord-276260-iccaqz8u	96	5	.	.	NNP
cord-276260-iccaqz8u	96	6	2020	2020	CD
cord-276260-iccaqz8u	96	7	)	)	-RRB-
cord-276260-iccaqz8u	96	8	.	.	.
cord-276260-iccaqz8u	97	1	The	the	DT
cord-276260-iccaqz8u	97	2	potential	potential	NN
cord-276260-iccaqz8u	97	3	of	of	IN
cord-276260-iccaqz8u	97	4	the	the	DT
cord-276260-iccaqz8u	97	5	ACE2	ACE2	NNP
cord-276260-iccaqz8u	97	6	-Ang-(1	-Ang-(1	:
cord-276260-iccaqz8u	97	7	-	-	SYM
cord-276260-iccaqz8u	97	8	7	7	CD
cord-276260-iccaqz8u	97	9	)	)	-RRB-
cord-276260-iccaqz8u	98	1	-MasR	-MasR	NNP
cord-276260-iccaqz8u	99	1	axis	axis	NN
cord-276260-iccaqz8u	99	2	has	have	VBZ
cord-276260-iccaqz8u	99	3	furthermore	furthermore	RB
cord-276260-iccaqz8u	99	4	been	be	VBN
cord-276260-iccaqz8u	99	5	recognized	recognize	VBN
cord-276260-iccaqz8u	99	6	as	as	IN
cord-276260-iccaqz8u	99	7	witnessed	witness	VBN
cord-276260-iccaqz8u	99	8	by	by	IN
cord-276260-iccaqz8u	99	9	registered	register	VBN
cord-276260-iccaqz8u	99	10	clinical	clinical	JJ
cord-276260-iccaqz8u	99	11	trials	trial	NNS
cord-276260-iccaqz8u	99	12	of	of	IN
cord-276260-iccaqz8u	99	13	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	99	14	-	-	HYPH
cord-276260-iccaqz8u	99	15	7	7	CD
cord-276260-iccaqz8u	99	16	)	)	-RRB-
cord-276260-iccaqz8u	99	17	in	in	IN
cord-276260-iccaqz8u	99	18	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	99	19	(	(	-LRB-
cord-276260-iccaqz8u	99	20	Clinical-Trials.gov	clinical-trials.gov	NN
cord-276260-iccaqz8u	99	21	,	,	,
cord-276260-iccaqz8u	99	22	Identifiers	identifier	NNS
cord-276260-iccaqz8u	99	23	:	:	:
cord-276260-iccaqz8u	99	24	NCT04332666	NCT04332666	NNP
cord-276260-iccaqz8u	99	25	;	;	:
cord-276260-iccaqz8u	100	1	NCT04375124	NCT04375124	NNP
cord-276260-iccaqz8u	100	2	;	;	:
cord-276260-iccaqz8u	100	3	NCT04401423	NCT04401423	NNP
cord-276260-iccaqz8u	100	4	)	)	-RRB-
cord-276260-iccaqz8u	100	5	.	.	.
cord-276260-iccaqz8u	101	1	However	however	RB
cord-276260-iccaqz8u	101	2	,	,	,
cord-276260-iccaqz8u	101	3	endogenous	endogenous	JJ
cord-276260-iccaqz8u	101	4	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	101	5	-	-	HYPH
cord-276260-iccaqz8u	101	6	7	7	CD
cord-276260-iccaqz8u	101	7	)	)	-RRB-
cord-276260-iccaqz8u	101	8	lacks	lack	VBZ
cord-276260-iccaqz8u	101	9	receptor	receptor	NN
cord-276260-iccaqz8u	101	10	specificity	specificity	NN
cord-276260-iccaqz8u	101	11	.	.	.
cord-276260-iccaqz8u	102	1	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	102	2	-	-	HYPH
cord-276260-iccaqz8u	102	3	7	7	CD
cord-276260-iccaqz8u	102	4	)	)	-RRB-
cord-276260-iccaqz8u	102	5	stimulates	stimulate	VBZ
cord-276260-iccaqz8u	102	6	in	in	IN
cord-276260-iccaqz8u	102	7	vivo	vivo	NN
cord-276260-iccaqz8u	102	8	the	the	DT
cord-276260-iccaqz8u	102	9	MasR	MasR	NNP
cord-276260-iccaqz8u	102	10	but	but	CC
cord-276260-iccaqz8u	102	11	in	in	IN
cord-276260-iccaqz8u	102	12	vitro	vitro	FW
cord-276260-iccaqz8u	102	13	studies	study	NNS
cord-276260-iccaqz8u	102	14	reported	report	VBD
cord-276260-iccaqz8u	102	15	biased	biased	JJ
cord-276260-iccaqz8u	102	16	agonism	agonism	NN
cord-276260-iccaqz8u	102	17	at	at	IN
cord-276260-iccaqz8u	102	18	the	the	DT
cord-276260-iccaqz8u	102	19	AT	AT	NNP
cord-276260-iccaqz8u	102	20	1	1	CD
cord-276260-iccaqz8u	102	21	R	r	NN
cord-276260-iccaqz8u	102	22	(	(	-LRB-
cord-276260-iccaqz8u	102	23	Galandrin	Galandrin	NNP
cord-276260-iccaqz8u	102	24	et	et	FW
cord-276260-iccaqz8u	102	25	al	al	NNP
cord-276260-iccaqz8u	102	26	.	.	.
cord-276260-iccaqz8u	102	27	2016	2016	CD
cord-276260-iccaqz8u	102	28	)	)	-RRB-
cord-276260-iccaqz8u	102	29	.	.	.
cord-276260-iccaqz8u	103	1	In	in	IN
cord-276260-iccaqz8u	103	2	addition	addition	NN
cord-276260-iccaqz8u	103	3	,	,	,
cord-276260-iccaqz8u	103	4	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	103	5	-	-	HYPH
cord-276260-iccaqz8u	103	6	7	7	NNP
cord-276260-iccaqz8u	103	7	)	)	-RRB-
cord-276260-iccaqz8u	103	8	is	be	VBZ
cord-276260-iccaqz8u	103	9	very	very	RB
cord-276260-iccaqz8u	103	10	rapidly	rapidly	RB
cord-276260-iccaqz8u	103	11	degraded	degrade	VBN
cord-276260-iccaqz8u	103	12	resulting	resulting	NN
cord-276260-iccaqz8u	103	13	in	in	IN
cord-276260-iccaqz8u	103	14	a	a	DT
cord-276260-iccaqz8u	103	15	half	half	JJ
cord-276260-iccaqz8u	103	16	-	-	HYPH
cord-276260-iccaqz8u	103	17	life	life	NN
cord-276260-iccaqz8u	103	18	of	of	IN
cord-276260-iccaqz8u	103	19	less	less	JJR
cord-276260-iccaqz8u	103	20	than	than	IN
cord-276260-iccaqz8u	103	21	a	a	DT
cord-276260-iccaqz8u	103	22	minute	minute	NN
cord-276260-iccaqz8u	103	23	in	in	IN
cord-276260-iccaqz8u	103	24	man	man	NN
cord-276260-iccaqz8u	103	25	.	.	.
cord-276260-iccaqz8u	104	1	In	in	IN
cord-276260-iccaqz8u	104	2	contrast	contrast	NN
cord-276260-iccaqz8u	104	3	,	,	,
cord-276260-iccaqz8u	104	4	specific	specific	JJ
cord-276260-iccaqz8u	104	5	and	and	CC
cord-276260-iccaqz8u	104	6	stable	stable	JJ
cord-276260-iccaqz8u	104	7	cyclic	cyclic	JJ
cord-276260-iccaqz8u	104	8	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	104	9	-	-	HYPH
cord-276260-iccaqz8u	104	10	7	7	NNP
cord-276260-iccaqz8u	104	11	)	)	-RRB-
cord-276260-iccaqz8u	104	12	exerts	exert	VBZ
cord-276260-iccaqz8u	104	13	multiple	multiple	JJ
cord-276260-iccaqz8u	104	14	therapeutic	therapeutic	JJ
cord-276260-iccaqz8u	104	15	effects	effect	NNS
cord-276260-iccaqz8u	104	16	in	in	IN
cord-276260-iccaqz8u	104	17	lung	lung	NN
cord-276260-iccaqz8u	104	18	tissue	tissue	NN
cord-276260-iccaqz8u	104	19	of	of	IN
cord-276260-iccaqz8u	104	20	animal	animal	NN
cord-276260-iccaqz8u	104	21	models	model	NNS
cord-276260-iccaqz8u	104	22	of	of	IN
cord-276260-iccaqz8u	104	23	acute	acute	JJ
cord-276260-iccaqz8u	104	24	and	and	CC
cord-276260-iccaqz8u	104	25	chronic	chronic	JJ
cord-276260-iccaqz8u	104	26	lung	lung	NN
cord-276260-iccaqz8u	104	27	injury	injury	NN
cord-276260-iccaqz8u	105	1	(	(	-LRB-
cord-276260-iccaqz8u	105	2	Wagenaar	Wagenaar	NNP
cord-276260-iccaqz8u	105	3	et	et	NNP
cord-276260-iccaqz8u	105	4	al	al	NNP
cord-276260-iccaqz8u	105	5	.	.	.
cord-276260-iccaqz8u	106	1	2013	2013	CD
cord-276260-iccaqz8u	106	2	;	;	:
cord-276260-iccaqz8u	106	3	Wösten	Wösten	NNP
cord-276260-iccaqz8u	106	4	-	-	HYPH
cord-276260-iccaqz8u	106	5	van	van	NNP
cord-276260-iccaqz8u	106	6	Asperen	Asperen	NNP
cord-276260-iccaqz8u	106	7	et	et	NNP
cord-276260-iccaqz8u	106	8	al	al	NNP
cord-276260-iccaqz8u	106	9	.	.	NNP
cord-276260-iccaqz8u	106	10	2011	2011	CD
cord-276260-iccaqz8u	106	11	)	)	-RRB-
cord-276260-iccaqz8u	106	12	.	.	.
cord-276260-iccaqz8u	107	1	In	in	IN
cord-276260-iccaqz8u	107	2	an	an	DT
cord-276260-iccaqz8u	107	3	animal	animal	NN
cord-276260-iccaqz8u	107	4	model	model	NN
cord-276260-iccaqz8u	107	5	of	of	IN
cord-276260-iccaqz8u	107	6	ARDS	ARDS	NNP
cord-276260-iccaqz8u	107	7	,	,	,
cord-276260-iccaqz8u	107	8	cyclic	cyclic	JJ
cord-276260-iccaqz8u	107	9	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	107	10	-	-	HYPH
cord-276260-iccaqz8u	107	11	7	7	CD
cord-276260-iccaqz8u	107	12	)	)	-RRB-
cord-276260-iccaqz8u	107	13	reduced	reduce	VBN
cord-276260-iccaqz8u	107	14	lung	lung	NN
cord-276260-iccaqz8u	107	15	injury	injury	NN
cord-276260-iccaqz8u	107	16	and	and	CC
cord-276260-iccaqz8u	107	17	inflammation	inflammation	NN
cord-276260-iccaqz8u	107	18	while	while	IN
cord-276260-iccaqz8u	107	19	improving	improve	VBG
cord-276260-iccaqz8u	107	20	blood	blood	NN
cord-276260-iccaqz8u	107	21	oxygenation	oxygenation	NN
cord-276260-iccaqz8u	107	22	(	(	-LRB-
cord-276260-iccaqz8u	107	23	Fig	Fig	NNP
cord-276260-iccaqz8u	107	24	.	.	.
cord-276260-iccaqz8u	107	25	1	1	CD
cord-276260-iccaqz8u	107	26	)	)	-RRB-
cord-276260-iccaqz8u	107	27	.	.	.
cord-276260-iccaqz8u	108	1	Cyclic	Cyclic	NNP
cord-276260-iccaqz8u	108	2	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	108	3	-	-	HYPH
cord-276260-iccaqz8u	108	4	7	7	CD
cord-276260-iccaqz8u	108	5	)	)	-RRB-
cord-276260-iccaqz8u	108	6	,	,	,
cord-276260-iccaqz8u	108	7	which	which	WDT
cord-276260-iccaqz8u	108	8	is	be	VBZ
cord-276260-iccaqz8u	108	9	fully	fully	RB
cord-276260-iccaqz8u	108	10	ACE	ace	NN
cord-276260-iccaqz8u	108	11	-	-	HYPH
cord-276260-iccaqz8u	108	12	resistant	resistant	JJ
cord-276260-iccaqz8u	108	13	,	,	,
cord-276260-iccaqz8u	108	14	did	do	VBD
cord-276260-iccaqz8u	108	15	not	not	RB
cord-276260-iccaqz8u	108	16	change	change	VB
cord-276260-iccaqz8u	108	17	the	the	DT
cord-276260-iccaqz8u	108	18	blood	blood	NN
cord-276260-iccaqz8u	108	19	pressure	pressure	NN
cord-276260-iccaqz8u	108	20	(	(	-LRB-
cord-276260-iccaqz8u	108	21	Wösten	Wösten	NNP
cord-276260-iccaqz8u	108	22	-	-	HYPH
cord-276260-iccaqz8u	108	23	van	van	NNP
cord-276260-iccaqz8u	108	24	Asperen	Asperen	NNP
cord-276260-iccaqz8u	108	25	et	et	NNP
cord-276260-iccaqz8u	108	26	al	al	NNP
cord-276260-iccaqz8u	108	27	.	.	NNP
cord-276260-iccaqz8u	108	28	2011	2011	CD
cord-276260-iccaqz8u	108	29	)	)	-RRB-
cord-276260-iccaqz8u	108	30	.	.	.
cord-276260-iccaqz8u	109	1	In	in	IN
cord-276260-iccaqz8u	109	2	addition	addition	NN
cord-276260-iccaqz8u	109	3	to	to	IN
cord-276260-iccaqz8u	109	4	the	the	DT
cord-276260-iccaqz8u	109	5	acute	acute	JJ
cord-276260-iccaqz8u	109	6	and	and	CC
cord-276260-iccaqz8u	109	7	sub	sub	JJ
cord-276260-iccaqz8u	109	8	-	-	JJ
cord-276260-iccaqz8u	109	9	chronic	chronic	JJ
cord-276260-iccaqz8u	109	10	effects	effect	NNS
cord-276260-iccaqz8u	109	11	in	in	IN
cord-276260-iccaqz8u	109	12	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	109	13	,	,	,
cord-276260-iccaqz8u	109	14	stable	stable	JJ
cord-276260-iccaqz8u	109	15	AT	at	IN
cord-276260-iccaqz8u	109	16	2	2	CD
cord-276260-iccaqz8u	109	17	R	r	NN
cord-276260-iccaqz8u	109	18	agonists	agonist	NNS
cord-276260-iccaqz8u	110	1	(	(	-LRB-
cord-276260-iccaqz8u	110	2	Bruce	Bruce	NNP
cord-276260-iccaqz8u	110	3	et	et	NNP
cord-276260-iccaqz8u	110	4	al	al	NNP
cord-276260-iccaqz8u	110	5	.	.	NNP
cord-276260-iccaqz8u	110	6	2015	2015	CD
cord-276260-iccaqz8u	110	7	)	)	-RRB-
cord-276260-iccaqz8u	110	8	may	may	MD
cord-276260-iccaqz8u	110	9	reduce	reduce	VB
cord-276260-iccaqz8u	110	10	COVID-19associated	COVID-19associated	NNP
cord-276260-iccaqz8u	110	11	long	long	JJ
cord-276260-iccaqz8u	110	12	term	term	NN
cord-276260-iccaqz8u	110	13	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	110	14	dysfunction	dysfunction	NN
cord-276260-iccaqz8u	110	15	.	.	.
cord-276260-iccaqz8u	111	1	Besides	besides	IN
cord-276260-iccaqz8u	111	2	the	the	DT
cord-276260-iccaqz8u	111	3	lungs	lung	NNS
cord-276260-iccaqz8u	111	4	,	,	,
cord-276260-iccaqz8u	111	5	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	111	6	also	also	RB
cord-276260-iccaqz8u	111	7	affects	affect	VBZ
cord-276260-iccaqz8u	111	8	heart	heart	NN
cord-276260-iccaqz8u	111	9	,	,	,
cord-276260-iccaqz8u	111	10	kidney	kidney	NN
cord-276260-iccaqz8u	111	11	,	,	,
cord-276260-iccaqz8u	111	12	liver	liver	NN
cord-276260-iccaqz8u	111	13	,	,	,
cord-276260-iccaqz8u	111	14	gastrointestinal	gastrointestinal	JJ
cord-276260-iccaqz8u	111	15	and	and	CC
cord-276260-iccaqz8u	111	16	the	the	DT
cord-276260-iccaqz8u	111	17	central	central	JJ
cord-276260-iccaqz8u	111	18	nervous	nervous	JJ
cord-276260-iccaqz8u	111	19	systems	system	NNS
cord-276260-iccaqz8u	111	20	(	(	-LRB-
cord-276260-iccaqz8u	111	21	Gan	Gan	NNP
cord-276260-iccaqz8u	111	22	et	et	FW
cord-276260-iccaqz8u	111	23	al	al	NNP
cord-276260-iccaqz8u	111	24	.	.	NNP
cord-276260-iccaqz8u	111	25	2020	2020	CD
cord-276260-iccaqz8u	111	26	)	)	-RRB-
cord-276260-iccaqz8u	111	27	.	.	.
cord-276260-iccaqz8u	112	1	In	in	IN
cord-276260-iccaqz8u	112	2	view	view	NN
cord-276260-iccaqz8u	112	3	of	of	IN
cord-276260-iccaqz8u	112	4	the	the	DT
cord-276260-iccaqz8u	112	5	demonstrated	demonstrate	VBN
cord-276260-iccaqz8u	112	6	general	general	JJ
cord-276260-iccaqz8u	112	7	therapeutic	therapeutic	JJ
cord-276260-iccaqz8u	112	8	potential	potential	NN
cord-276260-iccaqz8u	112	9	of	of	IN
cord-276260-iccaqz8u	112	10	the	the	DT
cord-276260-iccaqz8u	112	11	Protective	Protective	NNP
cord-276260-iccaqz8u	112	12	Arm	Arm	NNP
cord-276260-iccaqz8u	112	13	of	of	IN
cord-276260-iccaqz8u	112	14	RAS	RAS	NNP
cord-276260-iccaqz8u	112	15	in	in	IN
cord-276260-iccaqz8u	112	16	these	these	DT
cord-276260-iccaqz8u	112	17	organs	organ	NNS
cord-276260-iccaqz8u	112	18	and	and	CC
cord-276260-iccaqz8u	112	19	systems	system	NNS
cord-276260-iccaqz8u	113	1	(	(	-LRB-
cord-276260-iccaqz8u	113	2	Unger	Unger	NNP
cord-276260-iccaqz8u	113	3	et	et	NNP
cord-276260-iccaqz8u	113	4	al	al	NNP
cord-276260-iccaqz8u	113	5	.	.	.
cord-276260-iccaqz8u	113	6	2015	2015	CD
cord-276260-iccaqz8u	113	7	)	)	-RRB-
cord-276260-iccaqz8u	113	8	,	,	,
cord-276260-iccaqz8u	113	9	treatment	treatment	NN
cord-276260-iccaqz8u	113	10	of	of	IN
cord-276260-iccaqz8u	113	11	severe	severe	JJ
cord-276260-iccaqz8u	113	12	ARDS	ARDS	NNP
cord-276260-iccaqz8u	113	13	in	in	IN
cord-276260-iccaqz8u	113	14	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	113	15	with	with	IN
cord-276260-iccaqz8u	113	16	AT	AT	NNP
cord-276260-iccaqz8u	113	17	2	2	CD
cord-276260-iccaqz8u	113	18	R	r	NN
cord-276260-iccaqz8u	113	19	and	and	CC
cord-276260-iccaqz8u	113	20	MasR	MasR	NNP
cord-276260-iccaqz8u	113	21	agonists	agonist	NNS
cord-276260-iccaqz8u	113	22	may	may	MD
cord-276260-iccaqz8u	113	23	concomitantly	concomitantly	RB
cord-276260-iccaqz8u	113	24	confer	confer	VB
cord-276260-iccaqz8u	113	25	beneficial	beneficial	JJ
cord-276260-iccaqz8u	113	26	effects	effect	NNS
cord-276260-iccaqz8u	113	27	that	that	WDT
cord-276260-iccaqz8u	113	28	reduce	reduce	VBP
cord-276260-iccaqz8u	113	29	the	the	DT
cord-276260-iccaqz8u	113	30	overall	overall	JJ
cord-276260-iccaqz8u	113	31	end	end	NN
cord-276260-iccaqz8u	113	32	-	-	HYPH
cord-276260-iccaqz8u	113	33	organ	organ	NN
cord-276260-iccaqz8u	113	34	damage	damage	NN
cord-276260-iccaqz8u	113	35	of	of	IN
cord-276260-iccaqz8u	113	36	this	this	DT
cord-276260-iccaqz8u	113	37	disease	disease	NN
cord-276260-iccaqz8u	113	38	.	.	.
cord-276260-iccaqz8u	114	1	In	in	IN
cord-276260-iccaqz8u	114	2	conclusion	conclusion	NN
cord-276260-iccaqz8u	114	3	,	,	,
cord-276260-iccaqz8u	114	4	available	available	JJ
cord-276260-iccaqz8u	114	5	data	datum	NNS
cord-276260-iccaqz8u	114	6	indicate	indicate	VBP
cord-276260-iccaqz8u	114	7	the	the	DT
cord-276260-iccaqz8u	114	8	perspective	perspective	NN
cord-276260-iccaqz8u	114	9	of	of	IN
cord-276260-iccaqz8u	114	10	an	an	DT
cord-276260-iccaqz8u	114	11	effective	effective	JJ
cord-276260-iccaqz8u	114	12	strategy	strategy	NN
cord-276260-iccaqz8u	114	13	for	for	IN
cord-276260-iccaqz8u	114	14	treatment	treatment	NN
cord-276260-iccaqz8u	114	15	of	of	IN
cord-276260-iccaqz8u	114	16	ARDS	ARDS	NNP
cord-276260-iccaqz8u	114	17	and	and	CC
cord-276260-iccaqz8u	114	18	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	114	19	by	by	IN
cord-276260-iccaqz8u	114	20	direct	direct	JJ
cord-276260-iccaqz8u	114	21	and	and	CC
cord-276260-iccaqz8u	114	22	selective	selective	JJ
cord-276260-iccaqz8u	114	23	stimulation	stimulation	NN
cord-276260-iccaqz8u	114	24	of	of	IN
cord-276260-iccaqz8u	114	25	the	the	DT
cord-276260-iccaqz8u	114	26	Protective	Protective	NNP
cord-276260-iccaqz8u	114	27	Arm	Arm	NNP
cord-276260-iccaqz8u	114	28	of	of	IN
cord-276260-iccaqz8u	114	29	RAS	RAS	NNP
cord-276260-iccaqz8u	114	30	by	by	IN
cord-276260-iccaqz8u	114	31	AT	AT	NNP
cord-276260-iccaqz8u	114	32	2	2	CD
cord-276260-iccaqz8u	114	33	R	r	NN
cord-276260-iccaqz8u	114	34	-	-	:
cord-276260-iccaqz8u	114	35	or	or	CC
cord-276260-iccaqz8u	114	36	MasR	MasR	NNP
cord-276260-iccaqz8u	114	37	-	-	HYPH
cord-276260-iccaqz8u	114	38	specific	specific	JJ
cord-276260-iccaqz8u	114	39	,	,	,
cord-276260-iccaqz8u	114	40	peptidase	peptidase	NN
cord-276260-iccaqz8u	114	41	-	-	HYPH
cord-276260-iccaqz8u	114	42	resistant	resistant	JJ
cord-276260-iccaqz8u	114	43	agonists	agonist	NNS
cord-276260-iccaqz8u	114	44	.	.	.
cord-276260-iccaqz8u	115	1	The	the	DT
cord-276260-iccaqz8u	115	2	data	datum	NNS
cord-276260-iccaqz8u	115	3	converge	converge	VBP
cord-276260-iccaqz8u	115	4	to	to	IN
cord-276260-iccaqz8u	115	5	further	further	JJ
cord-276260-iccaqz8u	115	6	investigations	investigation	NNS
cord-276260-iccaqz8u	115	7	in	in	IN
cord-276260-iccaqz8u	115	8	viral	viral	JJ
cord-276260-iccaqz8u	115	9	pneumonia	pneumonia	NN
cord-276260-iccaqz8u	115	10	-	-	HYPH
cord-276260-iccaqz8u	115	11	mediated	mediate	VBN
cord-276260-iccaqz8u	115	12	ARDS	ARDS	NNP
cord-276260-iccaqz8u	115	13	models	model	NNS
cord-276260-iccaqz8u	115	14	.	.	.
cord-276260-iccaqz8u	116	1	Abbreviations	abbreviation	NNS
cord-276260-iccaqz8u	116	2	RAS	RAS	NNP
cord-276260-iccaqz8u	116	3	:	:	:
cord-276260-iccaqz8u	117	1	Renin	renin	NN
cord-276260-iccaqz8u	117	2	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	117	3	system	system	NN
cord-276260-iccaqz8u	117	4	;	;	:
cord-276260-iccaqz8u	117	5	SARS	SARS	NNP
cord-276260-iccaqz8u	117	6	:	:	:
cord-276260-iccaqz8u	117	7	Severe	severe	JJ
cord-276260-iccaqz8u	117	8	acute	acute	JJ
cord-276260-iccaqz8u	117	9	respiratory	respiratory	JJ
cord-276260-iccaqz8u	117	10	syndrome	syndrome	NN
cord-276260-iccaqz8u	117	11	;	;	:
cord-276260-iccaqz8u	117	12	CoV-2	cov-2	RB
cord-276260-iccaqz8u	117	13	:	:	:
cord-276260-iccaqz8u	117	14	Coronavirus	Coronavirus	NNP
cord-276260-iccaqz8u	117	15	2	2	CD
cord-276260-iccaqz8u	117	16	;	;	:
cord-276260-iccaqz8u	117	17	COVID-19	covid-19	CD
cord-276260-iccaqz8u	117	18	:	:	:
cord-276260-iccaqz8u	117	19	Coronavirus	Coronavirus	NNP
cord-276260-iccaqz8u	117	20	disease	disease	NN
cord-276260-iccaqz8u	117	21	2019	2019	CD
cord-276260-iccaqz8u	117	22	;	;	:
cord-276260-iccaqz8u	117	23	ARDS	ARDS	NNP
cord-276260-iccaqz8u	117	24	:	:	:
cord-276260-iccaqz8u	118	1	Acute	acute	JJ
cord-276260-iccaqz8u	118	2	respiratory	respiratory	JJ
cord-276260-iccaqz8u	118	3	distress	distress	NN
cord-276260-iccaqz8u	118	4	syndrome	syndrome	NN
cord-276260-iccaqz8u	118	5	;	;	:
cord-276260-iccaqz8u	119	1	AT	at	IN
cord-276260-iccaqz8u	119	2	2	2	CD
cord-276260-iccaqz8u	119	3	R	r	NN
cord-276260-iccaqz8u	119	4	:	:	:
cord-276260-iccaqz8u	119	5	Angiotensin	Angiotensin	NNP
cord-276260-iccaqz8u	119	6	II	II	NNP
cord-276260-iccaqz8u	119	7	type	type	NN
cord-276260-iccaqz8u	119	8	2	2	CD
cord-276260-iccaqz8u	119	9	receptor	receptor	NN
cord-276260-iccaqz8u	119	10	;	;	:
cord-276260-iccaqz8u	119	11	MasR	MasR	NNP
cord-276260-iccaqz8u	119	12	:	:	:
cord-276260-iccaqz8u	120	1	Mas	Mas	NNP
cord-276260-iccaqz8u	120	2	receptor	receptor	NN
cord-276260-iccaqz8u	120	3	;	;	:
cord-276260-iccaqz8u	120	4	ARB	arb	NN
cord-276260-iccaqz8u	120	5	:	:	:
cord-276260-iccaqz8u	120	6	Angiotensin	Angiotensin	NNP
cord-276260-iccaqz8u	120	7	II	II	NNP
cord-276260-iccaqz8u	120	8	type	type	NN
cord-276260-iccaqz8u	120	9	1	1	CD
cord-276260-iccaqz8u	120	10	receptor	receptor	NN
cord-276260-iccaqz8u	120	11	blocker	blocker	NN
cord-276260-iccaqz8u	120	12	;	;	:
cord-276260-iccaqz8u	120	13	ACE	ace	NN
cord-276260-iccaqz8u	120	14	:	:	:
cord-276260-iccaqz8u	120	15	Angiotensin	angiotensin	NN
cord-276260-iccaqz8u	120	16	converting	convert	VBG
cord-276260-iccaqz8u	120	17	enzyme	enzyme	NN
cord-276260-iccaqz8u	120	18	;	;	:
cord-276260-iccaqz8u	120	19	ACEi	acei	NN
cord-276260-iccaqz8u	120	20	:	:	:
cord-276260-iccaqz8u	120	21	Angiotensin	angiotensin	NN
cord-276260-iccaqz8u	120	22	converting	convert	VBG
cord-276260-iccaqz8u	120	23	enzyme	enzyme	NN
cord-276260-iccaqz8u	120	24	inhibitor	inhibitor	NN
cord-276260-iccaqz8u	120	25	;	;	:
cord-276260-iccaqz8u	120	26	Ang	Ang	NNP
cord-276260-iccaqz8u	120	27	II	II	NNP
cord-276260-iccaqz8u	120	28	:	:	:
cord-276260-iccaqz8u	120	29	Angiotensin	Angiotensin	NNP
cord-276260-iccaqz8u	120	30	II	II	NNP
cord-276260-iccaqz8u	120	31	;	;	:
cord-276260-iccaqz8u	120	32	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	120	33	-	-	HYPH
cord-276260-iccaqz8u	120	34	7	7	CD
cord-276260-iccaqz8u	120	35	)	)	-RRB-
cord-276260-iccaqz8u	120	36	:	:	:
cord-276260-iccaqz8u	120	37	Angiotensin-(1	Angiotensin-(1	NNP
cord-276260-iccaqz8u	120	38	-	-	HYPH
cord-276260-iccaqz8u	120	39	7	7	CD
cord-276260-iccaqz8u	120	40	)	)	-RRB-
cord-276260-iccaqz8u	121	1	Selective	selective	JJ
cord-276260-iccaqz8u	121	2	activation	activation	NN
cord-276260-iccaqz8u	121	3	of	of	IN
cord-276260-iccaqz8u	121	4	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	121	5	AT2	at2	NN
cord-276260-iccaqz8u	121	6	receptors	receptor	NNS
cord-276260-iccaqz8u	121	7	attenuates	attenuate	VBZ
cord-276260-iccaqz8u	121	8	progression	progression	NN
cord-276260-iccaqz8u	121	9	of	of	IN
cord-276260-iccaqz8u	121	10	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	121	11	hypertension	hypertension	NN
cord-276260-iccaqz8u	121	12	and	and	CC
cord-276260-iccaqz8u	121	13	inhibits	inhibit	VBZ
cord-276260-iccaqz8u	121	14	cardiopulmonary	cardiopulmonary	JJ
cord-276260-iccaqz8u	121	15	fibrosis	fibrosis	NN
cord-276260-iccaqz8u	121	16	Angiotensin-(1	Angiotensin-(1	NNP
cord-276260-iccaqz8u	121	17	-	-	HYPH
cord-276260-iccaqz8u	121	18	7	7	CD
cord-276260-iccaqz8u	121	19	)	)	-RRB-
cord-276260-iccaqz8u	121	20	and	and	CC
cord-276260-iccaqz8u	121	21	the	the	DT
cord-276260-iccaqz8u	121	22	regulation	regulation	NN
cord-276260-iccaqz8u	121	23	of	of	IN
cord-276260-iccaqz8u	121	24	antifibrotic	antifibrotic	JJ
cord-276260-iccaqz8u	121	25	signaling	signal	VBG
cord-276260-iccaqz8u	121	26	pathways	pathway	NNS
cord-276260-iccaqz8u	121	27	COVID-19	covid-19	VBP
cord-276260-iccaqz8u	121	28	and	and	CC
cord-276260-iccaqz8u	121	29	RAS	RAS	NNP
cord-276260-iccaqz8u	121	30	:	:	:
cord-276260-iccaqz8u	121	31	Unravelling	unravel	VBG
cord-276260-iccaqz8u	121	32	an	an	DT
cord-276260-iccaqz8u	121	33	unclear	unclear	JJ
cord-276260-iccaqz8u	121	34	relationship	relationship	NN
cord-276260-iccaqz8u	121	35	Cardioprotective	Cardioprotective	NNP
cord-276260-iccaqz8u	121	36	angiotensin-(1	angiotensin-(1	NNP
cord-276260-iccaqz8u	121	37	-	-	SYM
cord-276260-iccaqz8u	121	38	7	7	CD
cord-276260-iccaqz8u	121	39	)	)	-RRB-
cord-276260-iccaqz8u	121	40	peptide	peptide	NN
cord-276260-iccaqz8u	121	41	acts	act	NNS
cord-276260-iccaqz8u	121	42	as	as	IN
cord-276260-iccaqz8u	121	43	a	a	DT
cord-276260-iccaqz8u	121	44	natural	natural	RB
cord-276260-iccaqz8u	121	45	-	-	HYPH
cord-276260-iccaqz8u	121	46	biased	biased	JJ
cord-276260-iccaqz8u	121	47	ligand	ligand	NN
cord-276260-iccaqz8u	121	48	at	at	IN
cord-276260-iccaqz8u	121	49	the	the	DT
cord-276260-iccaqz8u	121	50	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	121	51	II	II	NNP
cord-276260-iccaqz8u	121	52	type	type	NN
cord-276260-iccaqz8u	121	53	1	1	CD
cord-276260-iccaqz8u	121	54	receptor	receptor	NN
cord-276260-iccaqz8u	121	55	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	121	56	as	as	IN
cord-276260-iccaqz8u	121	57	a	a	DT
cord-276260-iccaqz8u	121	58	viral	viral	JJ
cord-276260-iccaqz8u	121	59	functional	functional	JJ
cord-276260-iccaqz8u	121	60	ACE2	ACE2	NNP
cord-276260-iccaqz8u	121	61	deficiency	deficiency	NN
cord-276260-iccaqz8u	121	62	disorder	disorder	NN
cord-276260-iccaqz8u	121	63	with	with	IN
cord-276260-iccaqz8u	121	64	ACE2	ACE2	NNP
cord-276260-iccaqz8u	121	65	related	related	JJ
cord-276260-iccaqz8u	121	66	multi	multi	JJ
cord-276260-iccaqz8u	121	67	-	-	JJ
cord-276260-iccaqz8u	121	68	organ	organ	JJ
cord-276260-iccaqz8u	121	69	disease	disease	NN
cord-276260-iccaqz8u	121	70	Contentious	contentious	JJ
cord-276260-iccaqz8u	121	71	issues	issue	NNS
cord-276260-iccaqz8u	121	72	and	and	CC
cord-276260-iccaqz8u	121	73	evolving	evolve	VBG
cord-276260-iccaqz8u	121	74	concepts	concept	NNS
cord-276260-iccaqz8u	121	75	in	in	IN
cord-276260-iccaqz8u	121	76	the	the	DT
cord-276260-iccaqz8u	121	77	clinical	clinical	JJ
cord-276260-iccaqz8u	121	78	presentation	presentation	NN
cord-276260-iccaqz8u	121	79	and	and	CC
cord-276260-iccaqz8u	121	80	management	management	NN
cord-276260-iccaqz8u	121	81	of	of	IN
cord-276260-iccaqz8u	121	82	patients	patient	NNS
cord-276260-iccaqz8u	121	83	with	with	IN
cord-276260-iccaqz8u	121	84	COVID-19	covid-19	JJ
cord-276260-iccaqz8u	121	85	infection	infection	NN
cord-276260-iccaqz8u	121	86	with	with	IN
cord-276260-iccaqz8u	121	87	reference	reference	NN
cord-276260-iccaqz8u	121	88	to	to	IN
cord-276260-iccaqz8u	121	89	use	use	NN
cord-276260-iccaqz8u	121	90	of	of	IN
cord-276260-iccaqz8u	121	91	therapeutic	therapeutic	JJ
cord-276260-iccaqz8u	121	92	and	and	CC
cord-276260-iccaqz8u	121	93	other	other	JJ
cord-276260-iccaqz8u	121	94	drugs	drug	NNS
cord-276260-iccaqz8u	121	95	used	use	VBN
cord-276260-iccaqz8u	121	96	in	in	IN
cord-276260-iccaqz8u	121	97	co	co	JJ
cord-276260-iccaqz8u	121	98	-	-	JJ
cord-276260-iccaqz8u	121	99	morbid	morbid	JJ
cord-276260-iccaqz8u	121	100	diseases	disease	NNS
cord-276260-iccaqz8u	121	101	A	a	DT
cord-276260-iccaqz8u	121	102	potential	potential	JJ
cord-276260-iccaqz8u	121	103	therapeutic	therapeutic	JJ
cord-276260-iccaqz8u	121	104	role	role	NN
cord-276260-iccaqz8u	121	105	for	for	IN
cord-276260-iccaqz8u	121	106	Angiotensin	Angiotensin	NNP
cord-276260-iccaqz8u	121	107	Converting	Converting	NNP
cord-276260-iccaqz8u	121	108	Enzyme	Enzyme	NNP
cord-276260-iccaqz8u	121	109	2	2	CD
cord-276260-iccaqz8u	121	110	in	in	IN
cord-276260-iccaqz8u	121	111	human	human	JJ
cord-276260-iccaqz8u	121	112	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	121	113	arterial	arterial	JJ
cord-276260-iccaqz8u	121	114	hypertension	hypertension	NN
cord-276260-iccaqz8u	121	115	Endothelial	endothelial	JJ
cord-276260-iccaqz8u	121	116	cell	cell	NN
cord-276260-iccaqz8u	121	117	dysfunction	dysfunction	NN
cord-276260-iccaqz8u	121	118	:	:	:
cord-276260-iccaqz8u	121	119	a	a	DT
cord-276260-iccaqz8u	121	120	major	major	JJ
cord-276260-iccaqz8u	121	121	player	player	NN
cord-276260-iccaqz8u	121	122	in	in	IN
cord-276260-iccaqz8u	121	123	SARS	SARS	NNP
cord-276260-iccaqz8u	121	124	-	-	HYPH
cord-276260-iccaqz8u	121	125	CoV-2	CoV-2	NNP
cord-276260-iccaqz8u	121	126	infection	infection	NN
cord-276260-iccaqz8u	121	127	(	(	-LRB-
cord-276260-iccaqz8u	121	128	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	121	129	)	)	-RRB-
cord-276260-iccaqz8u	121	130	?	?	.
cord-276260-iccaqz8u	122	1	Understanding	understand	VBG
cord-276260-iccaqz8u	122	2	the	the	DT
cord-276260-iccaqz8u	122	3	renin	renin	NN
cord-276260-iccaqz8u	122	4	-	-	HYPH
cord-276260-iccaqz8u	122	5	angiotensinaldosterone	angiotensinaldosterone	NN
cord-276260-iccaqz8u	122	6	-	-	HYPH
cord-276260-iccaqz8u	122	7	SARS	SARS	NNP
cord-276260-iccaqz8u	122	8	-	-	HYPH
cord-276260-iccaqz8u	122	9	CoV	CoV	NNP
cord-276260-iccaqz8u	122	10	-	-	HYPH
cord-276260-iccaqz8u	122	11	Axis	axis	NN
cord-276260-iccaqz8u	122	12	:	:	:
cord-276260-iccaqz8u	122	13	a	a	DT
cord-276260-iccaqz8u	122	14	comprehensive	comprehensive	JJ
cord-276260-iccaqz8u	122	15	review	review	NN
cord-276260-iccaqz8u	122	16	Interactions	Interactions	NNPS
cord-276260-iccaqz8u	122	17	of	of	IN
cord-276260-iccaqz8u	122	18	coronaviruses	coronaviruse	NNS
cord-276260-iccaqz8u	122	19	with	with	IN
cord-276260-iccaqz8u	122	20	ACE2	ACE2	NNP
cord-276260-iccaqz8u	122	21	,	,	,
cord-276260-iccaqz8u	122	22	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	122	23	II	II	NNP
cord-276260-iccaqz8u	122	24	,	,	,
cord-276260-iccaqz8u	122	25	and	and	CC
cord-276260-iccaqz8u	122	26	RAS	RAS	NNP
cord-276260-iccaqz8u	122	27	inhibitors	inhibitor	NNS
cord-276260-iccaqz8u	122	28	-	-	:
cord-276260-iccaqz8u	122	29	lessons	lesson	NNS
cord-276260-iccaqz8u	122	30	form	form	NN
cord-276260-iccaqz8u	123	1	available	available	JJ
cord-276260-iccaqz8u	123	2	evidence	evidence	NN
cord-276260-iccaqz8u	123	3	and	and	CC
cord-276260-iccaqz8u	123	4	insights	insight	NNS
cord-276260-iccaqz8u	123	5	into	into	IN
cord-276260-iccaqz8u	123	6	COVID-19	COVID-19	NNP
cord-276260-iccaqz8u	123	7	A	a	DT
cord-276260-iccaqz8u	123	8	crucial	crucial	JJ
cord-276260-iccaqz8u	123	9	role	role	NN
cord-276260-iccaqz8u	123	10	of	of	IN
cord-276260-iccaqz8u	123	11	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	123	12	converting	convert	VBG
cord-276260-iccaqz8u	123	13	enzyme	enzyme	NN
cord-276260-iccaqz8u	123	14	2	2	CD
cord-276260-iccaqz8u	123	15	(	(	-LRB-
cord-276260-iccaqz8u	123	16	ACE2	ACE2	NNP
cord-276260-iccaqz8u	123	17	)	)	-RRB-
cord-276260-iccaqz8u	123	18	in	in	IN
cord-276260-iccaqz8u	123	19	SARS	SARS	NNP
cord-276260-iccaqz8u	123	20	coronavirus	coronavirus	NN
cord-276260-iccaqz8u	123	21	-	-	HYPH
cord-276260-iccaqz8u	123	22	induced	induce	VBN
cord-276260-iccaqz8u	123	23	lung	lung	NN
cord-276260-iccaqz8u	123	24	injury	injury	NN
cord-276260-iccaqz8u	123	25	Evidence	evidence	NN
cord-276260-iccaqz8u	123	26	for	for	IN
cord-276260-iccaqz8u	123	27	heterodimerization	heterodimerization	NN
cord-276260-iccaqz8u	123	28	and	and	CC
cord-276260-iccaqz8u	123	29	functional	functional	JJ
cord-276260-iccaqz8u	123	30	interaction	interaction	NN
cord-276260-iccaqz8u	123	31	of	of	IN
cord-276260-iccaqz8u	123	32	the	the	DT
cord-276260-iccaqz8u	123	33	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	123	34	type	type	NN
cord-276260-iccaqz8u	123	35	2	2	CD
cord-276260-iccaqz8u	123	36	receptor	receptor	NN
cord-276260-iccaqz8u	123	37	and	and	CC
cord-276260-iccaqz8u	123	38	the	the	DT
cord-276260-iccaqz8u	123	39	receptor	receptor	NN
cord-276260-iccaqz8u	123	40	MAS	MAS	NNP
cord-276260-iccaqz8u	123	41	Activation	Activation	NNP
cord-276260-iccaqz8u	123	42	of	of	IN
cord-276260-iccaqz8u	123	43	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	123	44	-	-	HYPH
cord-276260-iccaqz8u	123	45	7)/mas	7)/mas	CD
cord-276260-iccaqz8u	123	46	receptor	receptor	NN
cord-276260-iccaqz8u	123	47	is	be	VBZ
cord-276260-iccaqz8u	123	48	a	a	DT
cord-276260-iccaqz8u	123	49	possible	possible	JJ
cord-276260-iccaqz8u	123	50	strategy	strategy	NN
cord-276260-iccaqz8u	123	51	to	to	TO
cord-276260-iccaqz8u	123	52	treat	treat	VB
cord-276260-iccaqz8u	123	53	coronavirus	coronavirus	NN
cord-276260-iccaqz8u	123	54	(	(	-LRB-
cord-276260-iccaqz8u	123	55	SARS	SARS	NNP
cord-276260-iccaqz8u	123	56	-	-	HYPH
cord-276260-iccaqz8u	123	57	CoV-2	CoV-2	NNP
cord-276260-iccaqz8u	123	58	)	)	-RRB-
cord-276260-iccaqz8u	123	59	infection	infection	NN
cord-276260-iccaqz8u	124	1	Is	be	VBZ
cord-276260-iccaqz8u	124	2	the	the	DT
cord-276260-iccaqz8u	124	3	use	use	NN
cord-276260-iccaqz8u	124	4	of	of	IN
cord-276260-iccaqz8u	124	5	RAS	RAS	NNP
cord-276260-iccaqz8u	124	6	inhibitors	inhibitor	NNS
cord-276260-iccaqz8u	124	7	safe	safe	JJ
cord-276260-iccaqz8u	124	8	in	in	IN
cord-276260-iccaqz8u	124	9	the	the	DT
cord-276260-iccaqz8u	124	10	current	current	JJ
cord-276260-iccaqz8u	124	11	era	era	NN
cord-276260-iccaqz8u	124	12	of	of	IN
cord-276260-iccaqz8u	124	13	COVID-19	covid-19	JJ
cord-276260-iccaqz8u	124	14	pandemic	pandemic	NN
cord-276260-iccaqz8u	124	15	?	?	.
cord-276260-iccaqz8u	125	1	The	the	DT
cord-276260-iccaqz8u	125	2	selective	selective	JJ
cord-276260-iccaqz8u	125	3	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	125	4	II	ii	CD
cord-276260-iccaqz8u	125	5	type	type	NN
cord-276260-iccaqz8u	125	6	2	2	CD
cord-276260-iccaqz8u	125	7	receptor	receptor	NN
cord-276260-iccaqz8u	125	8	agonist	agonist	NN
cord-276260-iccaqz8u	125	9	,	,	,
cord-276260-iccaqz8u	125	10	compound	compound	NN
cord-276260-iccaqz8u	125	11	21	21	CD
cord-276260-iccaqz8u	125	12	,	,	,
cord-276260-iccaqz8u	125	13	attenuates	attenuate	VBZ
cord-276260-iccaqz8u	125	14	the	the	DT
cord-276260-iccaqz8u	125	15	progression	progression	NN
cord-276260-iccaqz8u	125	16	of	of	IN
cord-276260-iccaqz8u	125	17	lung	lung	NN
cord-276260-iccaqz8u	125	18	fibrosis	fibrosis	NN
cord-276260-iccaqz8u	125	19	and	and	CC
cord-276260-iccaqz8u	125	20	pulmonary	pulmonary	JJ
cord-276260-iccaqz8u	125	21	hypertension	hypertension	NN
cord-276260-iccaqz8u	125	22	in	in	IN
cord-276260-iccaqz8u	125	23	an	an	DT
cord-276260-iccaqz8u	125	24	experimental	experimental	JJ
cord-276260-iccaqz8u	125	25	model	model	NN
cord-276260-iccaqz8u	125	26	of	of	IN
cord-276260-iccaqz8u	125	27	bleomycin	bleomycin	NN
cord-276260-iccaqz8u	125	28	-	-	HYPH
cord-276260-iccaqz8u	125	29	induced	induce	VBN
cord-276260-iccaqz8u	125	30	lung	lung	NN
cord-276260-iccaqz8u	125	31	injury	injury	NN
cord-276260-iccaqz8u	125	32	Outcomes	Outcomes	NNP
cord-276260-iccaqz8u	125	33	in	in	IN
cord-276260-iccaqz8u	125	34	patients	patient	NNS
cord-276260-iccaqz8u	125	35	with	with	IN
cord-276260-iccaqz8u	125	36	COVID-19	covid-19	JJ
cord-276260-iccaqz8u	125	37	infection	infection	NN
cord-276260-iccaqz8u	125	38	taking	take	VBG
cord-276260-iccaqz8u	125	39	ACEi	ACEi	NNS
cord-276260-iccaqz8u	125	40	/	/	SYM
cord-276260-iccaqz8u	125	41	ARB	ARB	NNP
cord-276260-iccaqz8u	125	42	Angiotensin	Angiotensin	NNP
cord-276260-iccaqz8u	125	43	-	-	HYPH
cord-276260-iccaqz8u	125	44	converting	convert	VBG
cord-276260-iccaqz8u	125	45	enzyme	enzyme	NN
cord-276260-iccaqz8u	125	46	2	2	CD
cord-276260-iccaqz8u	125	47	and	and	CC
cord-276260-iccaqz8u	125	48	antihypertensives	antihypertensives	NNP
cord-276260-iccaqz8u	125	49	(	(	-LRB-
cord-276260-iccaqz8u	125	50	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	125	51	receptor	receptor	NN
cord-276260-iccaqz8u	125	52	blockers	blocker	NNS
cord-276260-iccaqz8u	125	53	and	and	CC
cord-276260-iccaqz8u	125	54	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	125	55	-	-	HYPH
cord-276260-iccaqz8u	125	56	converting	convert	VBG
cord-276260-iccaqz8u	125	57	enzyme	enzyme	NN
cord-276260-iccaqz8u	125	58	inhibitors	inhibitor	NNS
cord-276260-iccaqz8u	125	59	)	)	-RRB-
cord-276260-iccaqz8u	125	60	in	in	IN
cord-276260-iccaqz8u	125	61	coronavirus	coronavirus	NN
cord-276260-iccaqz8u	125	62	disease	disease	NN
cord-276260-iccaqz8u	125	63	2019	2019	CD
cord-276260-iccaqz8u	125	64	Rapid	Rapid	NNP
cord-276260-iccaqz8u	125	65	resonse	resonse	NN
cord-276260-iccaqz8u	125	66	:	:	:
cord-276260-iccaqz8u	125	67	preventing	prevent	VBG
cord-276260-iccaqz8u	125	68	a	a	DT
cord-276260-iccaqz8u	125	69	Covid-19	covid-19	NN
cord-276260-iccaqz8u	125	70	pandemic	pandemic	NN
cord-276260-iccaqz8u	125	71	:	:	:
cord-276260-iccaqz8u	125	72	ACE	ace	NN
cord-276260-iccaqz8u	125	73	inhibitors	inhibitor	NNS
cord-276260-iccaqz8u	125	74	as	as	IN
cord-276260-iccaqz8u	125	75	a	a	DT
cord-276260-iccaqz8u	125	76	potential	potential	JJ
cord-276260-iccaqz8u	125	77	risk	risk	NN
cord-276260-iccaqz8u	125	78	factor	factor	NN
cord-276260-iccaqz8u	125	79	for	for	IN
cord-276260-iccaqz8u	125	80	fatal	fatal	JJ
cord-276260-iccaqz8u	125	81	Covid-19	Covid-19	NNP
cord-276260-iccaqz8u	125	82	Risk	Risk	NNP
cord-276260-iccaqz8u	125	83	of	of	IN
cord-276260-iccaqz8u	125	84	ACE	ACE	NNP
cord-276260-iccaqz8u	125	85	inhibitor	inhibitor	NN
cord-276260-iccaqz8u	125	86	and	and	CC
cord-276260-iccaqz8u	125	87	ARB	ARB	NNP
cord-276260-iccaqz8u	125	88	usage	usage	NN
cord-276260-iccaqz8u	125	89	in	in	IN
cord-276260-iccaqz8u	125	90	Covid-10	Covid-10	NNP
cord-276260-iccaqz8u	125	91	:	:	:
cord-276260-iccaqz8u	125	92	evaluating	evaluate	VBG
cord-276260-iccaqz8u	125	93	the	the	DT
cord-276260-iccaqz8u	125	94	evidence	evidence	NN
cord-276260-iccaqz8u	125	95	Anti	anti	JJ
cord-276260-iccaqz8u	125	96	-	-	JJ
cord-276260-iccaqz8u	125	97	fibrotic	fibrotic	JJ
cord-276260-iccaqz8u	125	98	mechanisms	mechanism	NNS
cord-276260-iccaqz8u	125	99	of	of	IN
cord-276260-iccaqz8u	125	100	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	125	101	AT2	at2	NN
cord-276260-iccaqz8u	125	102	-receptor	-receptor	NN
cord-276260-iccaqz8u	125	103	stimulation	stimulation	NN
cord-276260-iccaqz8u	125	104	Regulation	regulation	NN
cord-276260-iccaqz8u	125	105	of	of	IN
cord-276260-iccaqz8u	125	106	alveolar	alveolar	JJ
cord-276260-iccaqz8u	125	107	epithelial	epithelial	JJ
cord-276260-iccaqz8u	125	108	cell	cell	NN
cord-276260-iccaqz8u	125	109	survival	survival	NN
cord-276260-iccaqz8u	125	110	by	by	IN
cord-276260-iccaqz8u	125	111	the	the	DT
cord-276260-iccaqz8u	125	112	ACE-2	ACE-2	NNP
cord-276260-iccaqz8u	125	113	/	/	SYM
cord-276260-iccaqz8u	125	114	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	125	115	1	1	CD
cord-276260-iccaqz8u	125	116	-	-	SYM
cord-276260-iccaqz8u	125	117	7	7	CD
cord-276260-iccaqz8u	125	118	/	/	SYM
cord-276260-iccaqz8u	125	119	mas	mas	NNP
cord-276260-iccaqz8u	125	120	axis	axis	NNP
cord-276260-iccaqz8u	126	1	The	the	DT
cord-276260-iccaqz8u	126	2	protective	protective	JJ
cord-276260-iccaqz8u	126	3	arm	arm	NN
cord-276260-iccaqz8u	126	4	of	of	IN
cord-276260-iccaqz8u	126	5	the	the	DT
cord-276260-iccaqz8u	126	6	renin	renin	NN
cord-276260-iccaqz8u	126	7	angiotensin	angiotensin	NNP
cord-276260-iccaqz8u	126	8	system	system	NN
cord-276260-iccaqz8u	126	9	.	.	.
cord-276260-iccaqz8u	127	1	Functional	functional	JJ
cord-276260-iccaqz8u	127	2	aspects	aspect	NNS
cord-276260-iccaqz8u	127	3	and	and	CC
cord-276260-iccaqz8u	127	4	therapeutic	therapeutic	JJ
cord-276260-iccaqz8u	127	5	implications	implication	NNS
cord-276260-iccaqz8u	127	6	Renin	renin	NN
cord-276260-iccaqz8u	127	7	-	-	HYPH
cord-276260-iccaqz8u	127	8	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	127	9	-	-	HYPH
cord-276260-iccaqz8u	127	10	aldosterone	aldosterone	NN
cord-276260-iccaqz8u	127	11	system	system	NN
cord-276260-iccaqz8u	127	12	inhibitors	inhibitor	NNS
cord-276260-iccaqz8u	127	13	in	in	IN
cord-276260-iccaqz8u	127	14	patients	patient	NNS
cord-276260-iccaqz8u	127	15	with	with	IN
cord-276260-iccaqz8u	127	16	Covid-19	Covid-19	NNP
cord-276260-iccaqz8u	127	17	Agonists	Agonists	NNPS
cord-276260-iccaqz8u	127	18	of	of	IN
cord-276260-iccaqz8u	127	19	MAS	MAS	NNP
cord-276260-iccaqz8u	127	20	oncogene	oncogene	NN
cord-276260-iccaqz8u	127	21	and	and	CC
cord-276260-iccaqz8u	127	22	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	127	23	II	ii	CD
cord-276260-iccaqz8u	127	24	type	type	NN
cord-276260-iccaqz8u	127	25	2	2	CD
cord-276260-iccaqz8u	127	26	receptors	receptor	NNS
cord-276260-iccaqz8u	127	27	attenuate	attenuate	VBP
cord-276260-iccaqz8u	127	28	cardiopulmonary	cardiopulmonary	JJ
cord-276260-iccaqz8u	127	29	disease	disease	NN
cord-276260-iccaqz8u	127	30	in	in	IN
cord-276260-iccaqz8u	127	31	rats	rat	NNS
cord-276260-iccaqz8u	127	32	with	with	IN
cord-276260-iccaqz8u	127	33	neonatal	neonatal	JJ
cord-276260-iccaqz8u	127	34	hyperoxia	hyperoxia	NN
cord-276260-iccaqz8u	127	35	-	-	HYPH
cord-276260-iccaqz8u	127	36	induced	induce	VBN
cord-276260-iccaqz8u	127	37	lung	lung	NN
cord-276260-iccaqz8u	127	38	injury	injury	NN
cord-276260-iccaqz8u	127	39	Good	good	JJ
cord-276260-iccaqz8u	127	40	or	or	CC
cord-276260-iccaqz8u	127	41	bad	bad	JJ
cord-276260-iccaqz8u	127	42	:	:	:
cord-276260-iccaqz8u	127	43	application	application	NN
cord-276260-iccaqz8u	127	44	of	of	IN
cord-276260-iccaqz8u	127	45	RAAS	RAAS	NNP
cord-276260-iccaqz8u	127	46	inhibitors	inhibitor	NNS
cord-276260-iccaqz8u	127	47	in	in	IN
cord-276260-iccaqz8u	127	48	COVID-19	covid-19	JJ
cord-276260-iccaqz8u	127	49	patients	patient	NNS
cord-276260-iccaqz8u	127	50	with	with	IN
cord-276260-iccaqz8u	127	51	cardiovascular	cardiovascular	JJ
cord-276260-iccaqz8u	127	52	comorbidities	comorbiditie	NNS
cord-276260-iccaqz8u	127	53	Acute	acute	JJ
cord-276260-iccaqz8u	127	54	respiratory	respiratory	JJ
cord-276260-iccaqz8u	127	55	distress	distress	NN
cord-276260-iccaqz8u	127	56	syndrome	syndrome	NN
cord-276260-iccaqz8u	127	57	leads	lead	VBZ
cord-276260-iccaqz8u	127	58	to	to	IN
cord-276260-iccaqz8u	127	59	reduced	reduce	VBN
cord-276260-iccaqz8u	127	60	ratio	ratio	NN
cord-276260-iccaqz8u	127	61	of	of	IN
cord-276260-iccaqz8u	127	62	ACE	ACE	NNP
cord-276260-iccaqz8u	127	63	/	/	SYM
cord-276260-iccaqz8u	127	64	ACE2	ACE2	NNP
cord-276260-iccaqz8u	127	65	activities	activity	NNS
cord-276260-iccaqz8u	127	66	and	and	CC
cord-276260-iccaqz8u	127	67	is	be	VBZ
cord-276260-iccaqz8u	127	68	prevented	prevent	VBN
cord-276260-iccaqz8u	127	69	by	by	IN
cord-276260-iccaqz8u	127	70	angiotensin-(1	angiotensin-(1	CD
cord-276260-iccaqz8u	127	71	-	-	SYM
cord-276260-iccaqz8u	127	72	7	7	CD
cord-276260-iccaqz8u	127	73	)	)	-RRB-
cord-276260-iccaqz8u	127	74	or	or	CC
cord-276260-iccaqz8u	127	75	an	an	DT
cord-276260-iccaqz8u	127	76	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	127	77	II	ii	CD
cord-276260-iccaqz8u	127	78	receptor	receptor	NN
cord-276260-iccaqz8u	127	79	antagonist	antagonist	NN
cord-276260-iccaqz8u	127	80	ACE2	ACE2	NNP
cord-276260-iccaqz8u	127	81	/	/	SYM
cord-276260-iccaqz8u	127	82	Ang-(1	Ang-(1	NNP
cord-276260-iccaqz8u	127	83	-	-	HYPH
cord-276260-iccaqz8u	127	84	7	7	CD
cord-276260-iccaqz8u	127	85	)	)	-RRB-
cord-276260-iccaqz8u	127	86	signaling	signal	VBG
cord-276260-iccaqz8u	127	87	and	and	CC
cord-276260-iccaqz8u	127	88	vascular	vascular	JJ
cord-276260-iccaqz8u	127	89	remodeling	remodeling	NN
cord-276260-iccaqz8u	128	1	Publisher	publisher	NN
cord-276260-iccaqz8u	128	2	's	's	POS
cord-276260-iccaqz8u	128	3	Note	Note	NNP
cord-276260-iccaqz8u	128	4	Springer	Springer	NNP
cord-276260-iccaqz8u	128	5	Nature	Nature	NNP
cord-276260-iccaqz8u	128	6	remains	remain	VBZ
cord-276260-iccaqz8u	128	7	neutral	neutral	JJ
cord-276260-iccaqz8u	128	8	with	with	IN
cord-276260-iccaqz8u	128	9	regard	regard	NN
cord-276260-iccaqz8u	128	10	to	to	IN
cord-276260-iccaqz8u	128	11	jurisdictional	jurisdictional	JJ
cord-276260-iccaqz8u	128	12	claims	claim	NNS
cord-276260-iccaqz8u	128	13	in	in	IN
cord-276260-iccaqz8u	128	14	published	publish	VBN
cord-276260-iccaqz8u	128	15	maps	map	NNS
cord-276260-iccaqz8u	128	16	and	and	CC
cord-276260-iccaqz8u	128	17	institutional	institutional	JJ
cord-276260-iccaqz8u	128	18	affiliations	affiliation	NNS
cord-276260-iccaqz8u	128	19	Not	not	RB
cord-276260-iccaqz8u	128	20	applicable	applicable	JJ
cord-276260-iccaqz8u	128	21	.	.	.
cord-276260-iccaqz8u	129	1	Authors	author	NNS
cord-276260-iccaqz8u	129	2	'	'	POS
cord-276260-iccaqz8u	129	3	contributions	contribution	NNS
cord-276260-iccaqz8u	130	1	PN	PN	NNP
cord-276260-iccaqz8u	130	2	wrote	write	VBD
cord-276260-iccaqz8u	130	3	the	the	DT
cord-276260-iccaqz8u	130	4	first	first	JJ
cord-276260-iccaqz8u	130	5	version	version	NN
cord-276260-iccaqz8u	130	6	of	of	IN
cord-276260-iccaqz8u	130	7	the	the	DT
cord-276260-iccaqz8u	130	8	manuscript	manuscript	NN
cord-276260-iccaqz8u	130	9	which	which	WDT
cord-276260-iccaqz8u	130	10	has	have	VBZ
cord-276260-iccaqz8u	130	11	been	be	VBN
cord-276260-iccaqz8u	130	12	extended	extend	VBN
cord-276260-iccaqz8u	130	13	by	by	IN
cord-276260-iccaqz8u	130	14	GNM	GNM	NNP
cord-276260-iccaqz8u	130	15	.	.	.
cord-276260-iccaqz8u	131	1	The	the	DT
cord-276260-iccaqz8u	131	2	author(s	author(s	NNP
cord-276260-iccaqz8u	131	3	)	)	-RRB-
cord-276260-iccaqz8u	131	4	read	read	VBD
cord-276260-iccaqz8u	131	5	and	and	CC
cord-276260-iccaqz8u	131	6	approved	approve	VBD
cord-276260-iccaqz8u	131	7	the	the	DT
cord-276260-iccaqz8u	131	8	final	final	JJ
cord-276260-iccaqz8u	131	9	manuscript	manuscript	NN
cord-276260-iccaqz8u	131	10	.	.	.
cord-276260-iccaqz8u	132	1	No	no	DT
cord-276260-iccaqz8u	132	2	funding	funding	NN
cord-276260-iccaqz8u	132	3	for	for	IN
cord-276260-iccaqz8u	132	4	this	this	DT
cord-276260-iccaqz8u	132	5	work	work	NN
cord-276260-iccaqz8u	132	6	has	have	VBZ
cord-276260-iccaqz8u	132	7	been	be	VBN
cord-276260-iccaqz8u	132	8	received	receive	VBN
cord-276260-iccaqz8u	132	9	.	.	.
cord-276260-iccaqz8u	133	1	Availability	availability	NN
cord-276260-iccaqz8u	133	2	of	of	IN
cord-276260-iccaqz8u	133	3	data	datum	NNS
cord-276260-iccaqz8u	133	4	and	and	CC
cord-276260-iccaqz8u	133	5	materials	material	NNS
cord-276260-iccaqz8u	133	6	Not	not	RB
cord-276260-iccaqz8u	133	7	applicable	applicable	JJ
cord-276260-iccaqz8u	133	8	.	.	.
cord-276260-iccaqz8u	134	1	Ethics	ethic	NNS
cord-276260-iccaqz8u	134	2	approval	approval	NN
cord-276260-iccaqz8u	134	3	and	and	CC
cord-276260-iccaqz8u	134	4	consent	consent	NN
cord-276260-iccaqz8u	134	5	to	to	TO
cord-276260-iccaqz8u	134	6	participate	participate	VB
cord-276260-iccaqz8u	134	7	Not	not	RB
cord-276260-iccaqz8u	134	8	applicable	applicable	JJ
cord-276260-iccaqz8u	134	9	.	.	.
cord-276260-iccaqz8u	135	1	Both	both	DT
cord-276260-iccaqz8u	135	2	authors	author	NNS
cord-276260-iccaqz8u	135	3	read	read	VBP
cord-276260-iccaqz8u	135	4	and	and	CC
cord-276260-iccaqz8u	135	5	agreed	agree	VBD
cord-276260-iccaqz8u	135	6	to	to	IN
cord-276260-iccaqz8u	135	7	the	the	DT
cord-276260-iccaqz8u	135	8	content	content	NN
cord-276260-iccaqz8u	135	9	of	of	IN
cord-276260-iccaqz8u	135	10	the	the	DT
cord-276260-iccaqz8u	135	11	final	final	JJ
cord-276260-iccaqz8u	135	12	manuscript	manuscript	NN
cord-276260-iccaqz8u	135	13	,	,	,
cord-276260-iccaqz8u	135	14	and	and	CC
cord-276260-iccaqz8u	135	15	consented	consent	VBD
cord-276260-iccaqz8u	135	16	on	on	IN
cord-276260-iccaqz8u	135	17	its	-PRON-	PRP$
cord-276260-iccaqz8u	135	18	publication	publication	NN
cord-276260-iccaqz8u	135	19	.	.	.
cord-276260-iccaqz8u	136	1	The	the	DT
cord-276260-iccaqz8u	136	2	authors	author	NNS
cord-276260-iccaqz8u	136	3	disclose	disclose	VBP
cord-276260-iccaqz8u	136	4	that	that	IN
cord-276260-iccaqz8u	136	5	their	-PRON-	PRP$
cord-276260-iccaqz8u	136	6	employer	employer	NN
cord-276260-iccaqz8u	136	7	,	,	,
cord-276260-iccaqz8u	136	8	LanthioPep	LanthioPep	NNP
cord-276260-iccaqz8u	136	9	B.V.	B.V.	NNP
cord-276260-iccaqz8u	136	10	,	,	,
cord-276260-iccaqz8u	136	11	is	be	VBZ
cord-276260-iccaqz8u	136	12	owner	owner	NN
cord-276260-iccaqz8u	136	13	of	of	IN
cord-276260-iccaqz8u	136	14	patents	patent	NNS
cord-276260-iccaqz8u	136	15	on	on	IN
cord-276260-iccaqz8u	136	16	angiotensin	angiotensin	NN
cord-276260-iccaqz8u	136	17	variants	variant	NNS
cord-276260-iccaqz8u	136	18	.	.	.
cord-276260-iccaqz8u	137	1	GNM	GNM	NNP
cord-276260-iccaqz8u	137	2	is	be	VBZ
cord-276260-iccaqz8u	137	3	director	director	NN
cord-276260-iccaqz8u	137	4	of	of	IN
cord-276260-iccaqz8u	137	5	LanthioPep	LanthioPep	NNP
cord-276260-iccaqz8u	137	6	B.V	B.V	NNP
cord-276260-iccaqz8u	137	7	..	..	.