id	sid	tid	token	lemma	pos
cord-281793-tj4m01s4	1	1	key	key	NN
cord-281793-tj4m01s4	1	2	:	:	:
cord-281793-tj4m01s4	1	3	cord-281793-tj4m01s4	cord-281793-tj4m01s4	NNP
cord-281793-tj4m01s4	1	4	authors	author	NNS
cord-281793-tj4m01s4	1	5	:	:	:
cord-281793-tj4m01s4	1	6	Ho	Ho	NNP
cord-281793-tj4m01s4	1	7	,	,	,
cord-281793-tj4m01s4	1	8	Mitchell	Mitchell	NNP
cord-281793-tj4m01s4	1	9	title	title	NN
cord-281793-tj4m01s4	1	10	:	:	:
cord-281793-tj4m01s4	1	11	Perspectives	perspective	NNS
cord-281793-tj4m01s4	1	12	on	on	IN
cord-281793-tj4m01s4	1	13	the	the	DT
cord-281793-tj4m01s4	1	14	development	development	NN
cord-281793-tj4m01s4	1	15	of	of	IN
cord-281793-tj4m01s4	1	16	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	1	17	antibodies	antibody	NNS
cord-281793-tj4m01s4	1	18	against	against	IN
cord-281793-tj4m01s4	1	19	SARS	SARS	NNP
cord-281793-tj4m01s4	1	20	-	-	HYPH
cord-281793-tj4m01s4	1	21	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	1	22	date	date	NN
cord-281793-tj4m01s4	1	23	:	:	:
cord-281793-tj4m01s4	1	24	2020	2020	CD
cord-281793-tj4m01s4	1	25	-	-	HYPH
cord-281793-tj4m01s4	1	26	05	05	CD
cord-281793-tj4m01s4	1	27	-	-	HYPH
cord-281793-tj4m01s4	1	28	20	20	CD
cord-281793-tj4m01s4	1	29	journal	journal	NN
cord-281793-tj4m01s4	1	30	:	:	:
cord-281793-tj4m01s4	2	1	Antib	Antib	NNP
cord-281793-tj4m01s4	2	2	Ther	Ther	NNP
cord-281793-tj4m01s4	2	3	DOI	DOI	NNP
cord-281793-tj4m01s4	2	4	:	:	:
cord-281793-tj4m01s4	3	1	10.1093	10.1093	CD
cord-281793-tj4m01s4	3	2	/	/	SYM
cord-281793-tj4m01s4	3	3	abt	abt	NNP
cord-281793-tj4m01s4	3	4	/	/	SYM
cord-281793-tj4m01s4	3	5	tbaa009	tbaa009	NNP
cord-281793-tj4m01s4	3	6	sha	sha	NNP
cord-281793-tj4m01s4	3	7	:	:	:
cord-281793-tj4m01s4	4	1	7bcb2c7d9ac0073e6ca72d6c3d6d4cb89d5a77f0	7bcb2c7d9ac0073e6ca72d6c3d6d4cb89d5a77f0	CD
cord-281793-tj4m01s4	4	2	doc_id	doc_id	CD
cord-281793-tj4m01s4	4	3	:	:	:
cord-281793-tj4m01s4	5	1	281793	281793	CD
cord-281793-tj4m01s4	5	2	cord_uid	cord_uid	NN
cord-281793-tj4m01s4	5	3	:	:	:
cord-281793-tj4m01s4	6	1	tj4m01s4	tj4m01s4	NNP
cord-281793-tj4m01s4	6	2	SARS	SARS	NNP
cord-281793-tj4m01s4	6	3	-	-	HYPH
cord-281793-tj4m01s4	6	4	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	6	5	gains	gain	VBZ
cord-281793-tj4m01s4	6	6	entry	entry	NN
cord-281793-tj4m01s4	6	7	to	to	IN
cord-281793-tj4m01s4	6	8	human	human	JJ
cord-281793-tj4m01s4	6	9	cells	cell	NNS
cord-281793-tj4m01s4	6	10	through	through	IN
cord-281793-tj4m01s4	6	11	its	-PRON-	PRP$
cord-281793-tj4m01s4	6	12	spike	spike	NN
cord-281793-tj4m01s4	6	13	(	(	-LRB-
cord-281793-tj4m01s4	6	14	S	s	NN
cord-281793-tj4m01s4	6	15	)	)	-RRB-
cord-281793-tj4m01s4	6	16	protein	protein	NN
cord-281793-tj4m01s4	6	17	binding	bind	VBG
cord-281793-tj4m01s4	6	18	to	to	IN
cord-281793-tj4m01s4	6	19	angiotensin	angiotensin	NN
cord-281793-tj4m01s4	6	20	-	-	HYPH
cord-281793-tj4m01s4	6	21	converting	convert	VBG
cord-281793-tj4m01s4	6	22	enzyme	enzyme	NN
cord-281793-tj4m01s4	6	23	2	2	CD
cord-281793-tj4m01s4	6	24	(	(	-LRB-
cord-281793-tj4m01s4	6	25	ACE2	ACE2	NNP
cord-281793-tj4m01s4	6	26	)	)	-RRB-
cord-281793-tj4m01s4	6	27	.	.	.
cord-281793-tj4m01s4	7	1	Therefore	therefore	RB
cord-281793-tj4m01s4	7	2	,	,	,
cord-281793-tj4m01s4	7	3	the	the	DT
cord-281793-tj4m01s4	7	4	receptor	receptor	NN
cord-281793-tj4m01s4	7	5	binding	bind	VBG
cord-281793-tj4m01s4	7	6	domain	domain	NN
cord-281793-tj4m01s4	7	7	(	(	-LRB-
cord-281793-tj4m01s4	7	8	RBD	RBD	NNP
cord-281793-tj4m01s4	7	9	)	)	-RRB-
cord-281793-tj4m01s4	7	10	of	of	IN
cord-281793-tj4m01s4	7	11	the	the	DT
cord-281793-tj4m01s4	7	12	S	S	NNP
cord-281793-tj4m01s4	7	13	protein	protein	NN
cord-281793-tj4m01s4	7	14	is	be	VBZ
cord-281793-tj4m01s4	7	15	the	the	DT
cord-281793-tj4m01s4	7	16	primary	primary	JJ
cord-281793-tj4m01s4	7	17	target	target	NN
cord-281793-tj4m01s4	7	18	for	for	IN
cord-281793-tj4m01s4	7	19	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	7	20	antibodies	antibody	NNS
cord-281793-tj4m01s4	7	21	.	.	.
cord-281793-tj4m01s4	8	1	Selection	selection	NN
cord-281793-tj4m01s4	8	2	of	of	IN
cord-281793-tj4m01s4	8	3	broad	broad	RB
cord-281793-tj4m01s4	8	4	-	-	HYPH
cord-281793-tj4m01s4	8	5	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	8	6	antibodies	antibody	NNS
cord-281793-tj4m01s4	8	7	against	against	IN
cord-281793-tj4m01s4	8	8	SARS	SARS	NNP
cord-281793-tj4m01s4	8	9	-	-	HYPH
cord-281793-tj4m01s4	8	10	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	8	11	and	and	CC
cord-281793-tj4m01s4	8	12	SARS	SARS	NNP
cord-281793-tj4m01s4	8	13	-	-	HYPH
cord-281793-tj4m01s4	8	14	CoV	CoV	NNP
cord-281793-tj4m01s4	8	15	is	be	VBZ
cord-281793-tj4m01s4	8	16	attractive	attractive	JJ
cord-281793-tj4m01s4	8	17	and	and	CC
cord-281793-tj4m01s4	8	18	might	may	MD
cord-281793-tj4m01s4	8	19	be	be	VB
cord-281793-tj4m01s4	8	20	useful	useful	JJ
cord-281793-tj4m01s4	8	21	for	for	IN
cord-281793-tj4m01s4	8	22	treating	treat	VBG
cord-281793-tj4m01s4	8	23	not	not	RB
cord-281793-tj4m01s4	8	24	only	only	RB
cord-281793-tj4m01s4	8	25	COVID-19	covid-19	VB
cord-281793-tj4m01s4	8	26	but	but	CC
cord-281793-tj4m01s4	8	27	also	also	RB
cord-281793-tj4m01s4	8	28	future	future	JJ
cord-281793-tj4m01s4	8	29	SARS	SARS	NNP
cord-281793-tj4m01s4	8	30	-	-	HYPH
cord-281793-tj4m01s4	8	31	related	relate	VBN
cord-281793-tj4m01s4	8	32	CoV	cov	NN
cord-281793-tj4m01s4	8	33	infections	infection	NNS
cord-281793-tj4m01s4	8	34	.	.	.
cord-281793-tj4m01s4	9	1	Broad	Broad	NNP
cord-281793-tj4m01s4	9	2	-	-	HYPH
cord-281793-tj4m01s4	9	3	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	9	4	antibodies	antibody	NNS
cord-281793-tj4m01s4	9	5	,	,	,
cord-281793-tj4m01s4	9	6	such	such	JJ
cord-281793-tj4m01s4	9	7	as	as	IN
cord-281793-tj4m01s4	9	8	47D11	47d11	CD
cord-281793-tj4m01s4	9	9	,	,	,
cord-281793-tj4m01s4	9	10	S309	S309	NNP
cord-281793-tj4m01s4	9	11	,	,	,
cord-281793-tj4m01s4	9	12	and	and	CC
cord-281793-tj4m01s4	9	13	VHH-72	VHH-72	NNP
cord-281793-tj4m01s4	9	14	,	,	,
cord-281793-tj4m01s4	9	15	have	have	VBP
cord-281793-tj4m01s4	9	16	been	be	VBN
cord-281793-tj4m01s4	9	17	reported	report	VBN
cord-281793-tj4m01s4	9	18	to	to	TO
cord-281793-tj4m01s4	9	19	target	target	VB
cord-281793-tj4m01s4	9	20	a	a	DT
cord-281793-tj4m01s4	9	21	conserved	conserved	JJ
cord-281793-tj4m01s4	9	22	region	region	NN
cord-281793-tj4m01s4	9	23	in	in	IN
cord-281793-tj4m01s4	9	24	the	the	DT
cord-281793-tj4m01s4	9	25	RBD	RBD	NNP
cord-281793-tj4m01s4	9	26	of	of	IN
cord-281793-tj4m01s4	9	27	the	the	DT
cord-281793-tj4m01s4	9	28	S1	S1	NNP
cord-281793-tj4m01s4	9	29	subunit	subunit	NN
cord-281793-tj4m01s4	9	30	.	.	.
cord-281793-tj4m01s4	10	1	The	the	DT
cord-281793-tj4m01s4	10	2	S2	S2	NNP
cord-281793-tj4m01s4	10	3	subunit	subunit	NN
cord-281793-tj4m01s4	10	4	required	require	VBN
cord-281793-tj4m01s4	10	5	for	for	IN
cord-281793-tj4m01s4	10	6	viral	viral	JJ
cord-281793-tj4m01s4	10	7	membrane	membrane	NN
cord-281793-tj4m01s4	10	8	fusion	fusion	NN
cord-281793-tj4m01s4	10	9	might	may	MD
cord-281793-tj4m01s4	10	10	be	be	VB
cord-281793-tj4m01s4	10	11	another	another	DT
cord-281793-tj4m01s4	10	12	target	target	NN
cord-281793-tj4m01s4	10	13	.	.	.
cord-281793-tj4m01s4	11	1	Due	due	IN
cord-281793-tj4m01s4	11	2	to	to	IN
cord-281793-tj4m01s4	11	3	their	-PRON-	PRP$
cord-281793-tj4m01s4	11	4	small	small	JJ
cord-281793-tj4m01s4	11	5	size	size	NN
cord-281793-tj4m01s4	11	6	and	and	CC
cord-281793-tj4m01s4	11	7	high	high	JJ
cord-281793-tj4m01s4	11	8	stability	stability	NN
cord-281793-tj4m01s4	11	9	,	,	,
cord-281793-tj4m01s4	11	10	single	single	JJ
cord-281793-tj4m01s4	11	11	-	-	HYPH
cord-281793-tj4m01s4	11	12	domain	domain	NN
cord-281793-tj4m01s4	11	13	antibodies	antibody	NNS
cord-281793-tj4m01s4	11	14	might	may	MD
cord-281793-tj4m01s4	11	15	have	have	VB
cord-281793-tj4m01s4	11	16	the	the	DT
cord-281793-tj4m01s4	11	17	ability	ability	NN
cord-281793-tj4m01s4	11	18	to	to	TO
cord-281793-tj4m01s4	11	19	be	be	VB
cord-281793-tj4m01s4	11	20	administered	administer	VBN
cord-281793-tj4m01s4	11	21	by	by	IN
cord-281793-tj4m01s4	11	22	an	an	DT
cord-281793-tj4m01s4	11	23	inhaler	inhaler	NN
cord-281793-tj4m01s4	11	24	making	make	VBG
cord-281793-tj4m01s4	11	25	them	-PRON-	PRP
cord-281793-tj4m01s4	11	26	potentially	potentially	RB
cord-281793-tj4m01s4	11	27	attractive	attractive	JJ
cord-281793-tj4m01s4	11	28	therapeutics	therapeutic	NNS
cord-281793-tj4m01s4	11	29	for	for	IN
cord-281793-tj4m01s4	11	30	respiratory	respiratory	JJ
cord-281793-tj4m01s4	11	31	infections	infection	NNS
cord-281793-tj4m01s4	11	32	.	.	.
cord-281793-tj4m01s4	12	1	A	a	DT
cord-281793-tj4m01s4	12	2	cocktail	cocktail	NN
cord-281793-tj4m01s4	12	3	strategy	strategy	NN
cord-281793-tj4m01s4	12	4	combining	combine	VBG
cord-281793-tj4m01s4	12	5	two	two	CD
cord-281793-tj4m01s4	12	6	(	(	-LRB-
cord-281793-tj4m01s4	12	7	or	or	CC
cord-281793-tj4m01s4	12	8	more	more	JJR
cord-281793-tj4m01s4	12	9	)	)	-RRB-
cord-281793-tj4m01s4	12	10	antibodies	antibody	NNS
cord-281793-tj4m01s4	12	11	that	that	WDT
cord-281793-tj4m01s4	12	12	recognize	recognize	VBP
cord-281793-tj4m01s4	12	13	different	different	JJ
cord-281793-tj4m01s4	12	14	parts	part	NNS
cord-281793-tj4m01s4	12	15	of	of	IN
cord-281793-tj4m01s4	12	16	the	the	DT
cord-281793-tj4m01s4	12	17	viral	viral	JJ
cord-281793-tj4m01s4	12	18	surface	surface	NN
cord-281793-tj4m01s4	12	19	that	that	WDT
cord-281793-tj4m01s4	12	20	interact	interact	VBP
cord-281793-tj4m01s4	12	21	with	with	IN
cord-281793-tj4m01s4	12	22	human	human	JJ
cord-281793-tj4m01s4	12	23	cells	cell	NNS
cord-281793-tj4m01s4	12	24	might	may	MD
cord-281793-tj4m01s4	12	25	be	be	VB
cord-281793-tj4m01s4	12	26	the	the	DT
cord-281793-tj4m01s4	12	27	most	most	RBS
cord-281793-tj4m01s4	12	28	effective	effective	JJ
cord-281793-tj4m01s4	12	29	.	.	.
cord-281793-tj4m01s4	13	1	COVID-19	COVID-19	NNP
cord-281793-tj4m01s4	13	2	is	be	VBZ
cord-281793-tj4m01s4	13	3	caused	cause	VBN
cord-281793-tj4m01s4	13	4	by	by	IN
cord-281793-tj4m01s4	13	5	the	the	DT
cord-281793-tj4m01s4	13	6	new	new	JJ
cord-281793-tj4m01s4	13	7	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	13	8	SARS	SARS	NNP
cord-281793-tj4m01s4	13	9	-	-	HYPH
cord-281793-tj4m01s4	13	10	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	13	11	(	(	-LRB-
cord-281793-tj4m01s4	13	12	initially	initially	RB
cord-281793-tj4m01s4	13	13	called	call	VBN
cord-281793-tj4m01s4	13	14	2019-nCoV	2019-ncov	CD
cord-281793-tj4m01s4	13	15	)	)	-RRB-
cord-281793-tj4m01s4	13	16	[	[	-LRB-
cord-281793-tj4m01s4	13	17	1	1	CD
cord-281793-tj4m01s4	13	18	,	,	,
cord-281793-tj4m01s4	13	19	2	2	CD
cord-281793-tj4m01s4	13	20	]	]	-RRB-
cord-281793-tj4m01s4	13	21	.	.	.
cord-281793-tj4m01s4	14	1	As	as	IN
cord-281793-tj4m01s4	14	2	of	of	IN
cord-281793-tj4m01s4	14	3	May	May	NNP
cord-281793-tj4m01s4	14	4	16	16	CD
cord-281793-tj4m01s4	14	5	,	,	,
cord-281793-tj4m01s4	14	6	2020	2020	CD
cord-281793-tj4m01s4	14	7	,	,	,
cord-281793-tj4m01s4	14	8	there	there	EX
cord-281793-tj4m01s4	14	9	are	be	VBP
cord-281793-tj4m01s4	14	10	4,632,903	4,632,903	CD
cord-281793-tj4m01s4	14	11	confirmed	confirm	VBN
cord-281793-tj4m01s4	14	12	cases	case	NNS
cord-281793-tj4m01s4	14	13	and	and	CC
cord-281793-tj4m01s4	14	14	311,739	311,739	CD
cord-281793-tj4m01s4	14	15	death	death	NN
cord-281793-tj4m01s4	14	16	worldwide	worldwide	RB
cord-281793-tj4m01s4	14	17	with	with	IN
cord-281793-tj4m01s4	14	18	188	188	CD
cord-281793-tj4m01s4	14	19	countries	country	NNS
cord-281793-tj4m01s4	14	20	affected	affect	VBN
cord-281793-tj4m01s4	14	21	(	(	-LRB-
cord-281793-tj4m01s4	14	22	https://coronavirus.jhu.edu/ma	https://coronavirus.jhu.edu/ma	NNP
cord-281793-tj4m01s4	14	23	p.html	p.html	NFP
cord-281793-tj4m01s4	14	24	)	)	-RRB-
cord-281793-tj4m01s4	14	25	.	.	.
cord-281793-tj4m01s4	15	1	It	-PRON-	PRP
cord-281793-tj4m01s4	15	2	is	be	VBZ
cord-281793-tj4m01s4	15	3	widely	widely	RB
cord-281793-tj4m01s4	15	4	believed	believe	VBN
cord-281793-tj4m01s4	15	5	that	that	IN
cord-281793-tj4m01s4	15	6	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	15	7	antibodies	antibody	NNS
cord-281793-tj4m01s4	15	8	can	can	MD
cord-281793-tj4m01s4	15	9	be	be	VB
cord-281793-tj4m01s4	15	10	used	use	VBN
cord-281793-tj4m01s4	15	11	to	to	TO
cord-281793-tj4m01s4	15	12	treat	treat	VB
cord-281793-tj4m01s4	15	13	COVID-19	COVID-19	NNP
cord-281793-tj4m01s4	15	14	by	by	IN
cord-281793-tj4m01s4	15	15	reducing	reduce	VBG
cord-281793-tj4m01s4	15	16	SARS	SARS	NNP
cord-281793-tj4m01s4	15	17	-	-	HYPH
cord-281793-tj4m01s4	15	18	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	15	19	infectivity	infectivity	NN
cord-281793-tj4m01s4	15	20	[	[	-LRB-
cord-281793-tj4m01s4	15	21	3	3	CD
cord-281793-tj4m01s4	15	22	]	]	-RRB-
cord-281793-tj4m01s4	15	23	.	.	.
cord-281793-tj4m01s4	16	1	In	in	IN
cord-281793-tj4m01s4	16	2	the	the	DT
cord-281793-tj4m01s4	16	3	current	current	JJ
cord-281793-tj4m01s4	16	4	issue	issue	NN
cord-281793-tj4m01s4	16	5	of	of	IN
cord-281793-tj4m01s4	16	6	Antibody	Antibody	NNP
cord-281793-tj4m01s4	16	7	Therapeutics	Therapeutics	NNP
cord-281793-tj4m01s4	16	8	,	,	,
cord-281793-tj4m01s4	16	9	two	two	CD
cord-281793-tj4m01s4	16	10	articles	article	NNS
cord-281793-tj4m01s4	16	11	related	relate	VBN
cord-281793-tj4m01s4	16	12	to	to	IN
cord-281793-tj4m01s4	16	13	COVID-19	COVID-19	NNP
cord-281793-tj4m01s4	16	14	have	have	VBP
cord-281793-tj4m01s4	16	15	been	be	VBN
cord-281793-tj4m01s4	16	16	published	publish	VBN
cord-281793-tj4m01s4	16	17	through	through	IN
cord-281793-tj4m01s4	16	18	a	a	DT
cord-281793-tj4m01s4	16	19	fast	fast	JJ
cord-281793-tj4m01s4	16	20	track	track	NN
cord-281793-tj4m01s4	16	21	peer	peer	NN
cord-281793-tj4m01s4	16	22	review	review	NN
cord-281793-tj4m01s4	16	23	,	,	,
cord-281793-tj4m01s4	16	24	revision	revision	NN
cord-281793-tj4m01s4	16	25	,	,	,
cord-281793-tj4m01s4	16	26	and	and	CC
cord-281793-tj4m01s4	16	27	production	production	NN
cord-281793-tj4m01s4	16	28	[	[	-LRB-
cord-281793-tj4m01s4	16	29	4	4	CD
cord-281793-tj4m01s4	16	30	,	,	,
cord-281793-tj4m01s4	16	31	5	5	CD
cord-281793-tj4m01s4	16	32	]	]	-RRB-
cord-281793-tj4m01s4	16	33	.	.	.
cord-281793-tj4m01s4	17	1	While	while	IN
cord-281793-tj4m01s4	17	2	most	most	JJS
cord-281793-tj4m01s4	17	3	publications	publication	NNS
cord-281793-tj4m01s4	17	4	in	in	IN
cord-281793-tj4m01s4	17	5	our	-PRON-	PRP$
cord-281793-tj4m01s4	17	6	journal	journal	NN
cord-281793-tj4m01s4	17	7	have	have	VBP
cord-281793-tj4m01s4	17	8	been	be	VBN
cord-281793-tj4m01s4	17	9	focused	focus	VBN
cord-281793-tj4m01s4	17	10	on	on	IN
cord-281793-tj4m01s4	17	11	cancer	cancer	NN
cord-281793-tj4m01s4	17	12	therapies	therapy	NNS
cord-281793-tj4m01s4	17	13	,	,	,
cord-281793-tj4m01s4	17	14	it	-PRON-	PRP
cord-281793-tj4m01s4	17	15	was	be	VBD
cord-281793-tj4m01s4	17	16	not	not	RB
cord-281793-tj4m01s4	17	17	the	the	DT
cord-281793-tj4m01s4	17	18	first	first	JJ
cord-281793-tj4m01s4	17	19	time	time	NN
cord-281793-tj4m01s4	17	20	that	that	WDT
cord-281793-tj4m01s4	17	21	Antibody	Antibody	NNP
cord-281793-tj4m01s4	17	22	Therapeutics	Therapeutics	NNP
cord-281793-tj4m01s4	17	23	published	publish	VBD
cord-281793-tj4m01s4	17	24	papers	paper	NNS
cord-281793-tj4m01s4	17	25	that	that	WDT
cord-281793-tj4m01s4	17	26	were	be	VBD
cord-281793-tj4m01s4	17	27	relevant	relevant	JJ
cord-281793-tj4m01s4	17	28	to	to	IN
cord-281793-tj4m01s4	17	29	antibody	antibody	NN
cord-281793-tj4m01s4	17	30	development	development	NN
cord-281793-tj4m01s4	17	31	for	for	IN
cord-281793-tj4m01s4	17	32	viral	viral	JJ
cord-281793-tj4m01s4	17	33	diseases	disease	NNS
cord-281793-tj4m01s4	17	34	.	.	.
cord-281793-tj4m01s4	18	1	In	in	IN
cord-281793-tj4m01s4	18	2	one	one	CD
cord-281793-tj4m01s4	18	3	previous	previous	JJ
cord-281793-tj4m01s4	18	4	study	study	NN
cord-281793-tj4m01s4	18	5	,	,	,
cord-281793-tj4m01s4	18	6	a	a	DT
cord-281793-tj4m01s4	18	7	human	human	JJ
cord-281793-tj4m01s4	18	8	papillomavirus	papillomavirus	NN
cord-281793-tj4m01s4	18	9	vaccine	vaccine	NN
cord-281793-tj4m01s4	18	10	using	use	VBG
cord-281793-tj4m01s4	18	11	a	a	DT
cord-281793-tj4m01s4	18	12	novel	novel	JJ
cord-281793-tj4m01s4	18	13	viruslike	viruslike	JJ
cord-281793-tj4m01s4	18	14	particle	particle	NN
cord-281793-tj4m01s4	18	15	was	be	VBD
cord-281793-tj4m01s4	18	16	shown	show	VBN
cord-281793-tj4m01s4	18	17	to	to	TO
cord-281793-tj4m01s4	18	18	induce	induce	VB
cord-281793-tj4m01s4	18	19	antibody	antibody	NN
cord-281793-tj4m01s4	18	20	response	response	NN
cord-281793-tj4m01s4	18	21	in	in	IN
cord-281793-tj4m01s4	18	22	Figure	figure	NN
cord-281793-tj4m01s4	18	23	1	1	CD
cord-281793-tj4m01s4	18	24	.	.	.
cord-281793-tj4m01s4	19	1	Development	development	NN
cord-281793-tj4m01s4	19	2	of	of	IN
cord-281793-tj4m01s4	19	3	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	19	4	antibodies	antibody	NNS
cord-281793-tj4m01s4	19	5	for	for	IN
cord-281793-tj4m01s4	19	6	treating	treat	VBG
cord-281793-tj4m01s4	19	7	COVID-19	covid-19	NN
cord-281793-tj4m01s4	19	8	.	.	.
cord-281793-tj4m01s4	20	1	In	in	IN
cord-281793-tj4m01s4	20	2	the	the	DT
cord-281793-tj4m01s4	20	3	receptor	receptor	NN
cord-281793-tj4m01s4	20	4	binding	bind	VBG
cord-281793-tj4m01s4	20	5	stage	stage	NN
cord-281793-tj4m01s4	20	6	,	,	,
cord-281793-tj4m01s4	20	7	the	the	DT
cord-281793-tj4m01s4	20	8	S1	S1	NNP
cord-281793-tj4m01s4	20	9	subunit	subunit	NN
cord-281793-tj4m01s4	20	10	of	of	IN
cord-281793-tj4m01s4	20	11	SARS	SARS	NNP
cord-281793-tj4m01s4	20	12	-	-	HYPH
cord-281793-tj4m01s4	20	13	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	20	14	binds	bind	VBZ
cord-281793-tj4m01s4	20	15	human	human	JJ
cord-281793-tj4m01s4	20	16	ACE2	ACE2	NNP
cord-281793-tj4m01s4	20	17	on	on	IN
cord-281793-tj4m01s4	20	18	the	the	DT
cord-281793-tj4m01s4	20	19	host	host	NN
cord-281793-tj4m01s4	20	20	cell	cell	NN
cord-281793-tj4m01s4	20	21	surface	surface	NN
cord-281793-tj4m01s4	20	22	.	.	.
cord-281793-tj4m01s4	21	1	Antibodies	antibody	NNS
cord-281793-tj4m01s4	21	2	that	that	WDT
cord-281793-tj4m01s4	21	3	bind	bind	VBP
cord-281793-tj4m01s4	21	4	the	the	DT
cord-281793-tj4m01s4	21	5	RBD	RBD	NNP
cord-281793-tj4m01s4	21	6	domain	domain	NN
cord-281793-tj4m01s4	21	7	on	on	IN
cord-281793-tj4m01s4	21	8	the	the	DT
cord-281793-tj4m01s4	21	9	S1	S1	NNP
cord-281793-tj4m01s4	21	10	subunit	subunit	NN
cord-281793-tj4m01s4	21	11	might	may	MD
cord-281793-tj4m01s4	21	12	block	block	VB
cord-281793-tj4m01s4	21	13	the	the	DT
cord-281793-tj4m01s4	21	14	interaction	interaction	NN
cord-281793-tj4m01s4	21	15	of	of	IN
cord-281793-tj4m01s4	21	16	the	the	DT
cord-281793-tj4m01s4	21	17	RBD	RBD	NNP
cord-281793-tj4m01s4	21	18	and	and	CC
cord-281793-tj4m01s4	21	19	the	the	DT
cord-281793-tj4m01s4	21	20	ACE2	ACE2	NNP
cord-281793-tj4m01s4	21	21	.	.	.
cord-281793-tj4m01s4	22	1	Crossreactive	crossreactive	JJ
cord-281793-tj4m01s4	22	2	antibodies	antibody	NNS
cord-281793-tj4m01s4	22	3	(	(	-LRB-
cord-281793-tj4m01s4	22	4	e.g.	e.g.	RB
cord-281793-tj4m01s4	22	5	,	,	,
cord-281793-tj4m01s4	22	6	47D11	47d11	CD
cord-281793-tj4m01s4	22	7	,	,	,
cord-281793-tj4m01s4	22	8	S309	S309	NNS
cord-281793-tj4m01s4	22	9	,	,	,
cord-281793-tj4m01s4	22	10	and	and	CC
cord-281793-tj4m01s4	22	11	VHH-72	VHH-72	NNP
cord-281793-tj4m01s4	22	12	)	)	-RRB-
cord-281793-tj4m01s4	22	13	that	that	WDT
cord-281793-tj4m01s4	22	14	bind	bind	VBP
cord-281793-tj4m01s4	22	15	highly	highly	RB
cord-281793-tj4m01s4	22	16	conserved	conserve	VBN
cord-281793-tj4m01s4	22	17	epitopes	epitope	NNS
cord-281793-tj4m01s4	22	18	on	on	IN
cord-281793-tj4m01s4	22	19	the	the	DT
cord-281793-tj4m01s4	22	20	RBDs	rbds	NN
cord-281793-tj4m01s4	22	21	of	of	IN
cord-281793-tj4m01s4	22	22	SARS	SARS	NNP
cord-281793-tj4m01s4	22	23	-	-	HYPH
cord-281793-tj4m01s4	22	24	CoV	CoV	NNP
cord-281793-tj4m01s4	22	25	and	and	CC
cord-281793-tj4m01s4	22	26	SARS	SARS	NNP
cord-281793-tj4m01s4	22	27	-	-	HYPH
cord-281793-tj4m01s4	22	28	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	22	29	could	could	MD
cord-281793-tj4m01s4	22	30	have	have	VB
cord-281793-tj4m01s4	22	31	broad	broad	JJ
cord-281793-tj4m01s4	22	32	neutralization	neutralization	NN
cord-281793-tj4m01s4	22	33	activities	activity	NNS
cord-281793-tj4m01s4	22	34	against	against	IN
cord-281793-tj4m01s4	22	35	viral	viral	JJ
cord-281793-tj4m01s4	22	36	infection	infection	NN
cord-281793-tj4m01s4	22	37	.	.	.
cord-281793-tj4m01s4	23	1	In	in	IN
cord-281793-tj4m01s4	23	2	the	the	DT
cord-281793-tj4m01s4	23	3	viral	viral	JJ
cord-281793-tj4m01s4	23	4	fusion	fusion	NN
cord-281793-tj4m01s4	23	5	stage	stage	NN
cord-281793-tj4m01s4	23	6	,	,	,
cord-281793-tj4m01s4	23	7	after	after	IN
cord-281793-tj4m01s4	23	8	the	the	DT
cord-281793-tj4m01s4	23	9	cleavage	cleavage	NN
cord-281793-tj4m01s4	23	10	of	of	IN
cord-281793-tj4m01s4	23	11	S1	s1	NN
cord-281793-tj4m01s4	23	12	subunit	subunit	NN
cord-281793-tj4m01s4	23	13	,	,	,
cord-281793-tj4m01s4	23	14	the	the	DT
cord-281793-tj4m01s4	23	15	viral	viral	JJ
cord-281793-tj4m01s4	23	16	fusion	fusion	NN
cord-281793-tj4m01s4	23	17	peptide	peptide	NN
cord-281793-tj4m01s4	23	18	(	(	-LRB-
cord-281793-tj4m01s4	23	19	FP	FP	NNP
cord-281793-tj4m01s4	23	20	)	)	-RRB-
cord-281793-tj4m01s4	23	21	on	on	IN
cord-281793-tj4m01s4	23	22	the	the	DT
cord-281793-tj4m01s4	23	23	S2	S2	NNP
cord-281793-tj4m01s4	23	24	subunit	subunit	NN
cord-281793-tj4m01s4	23	25	inserts	insert	VBZ
cord-281793-tj4m01s4	23	26	into	into	IN
cord-281793-tj4m01s4	23	27	the	the	DT
cord-281793-tj4m01s4	23	28	host	host	NN
cord-281793-tj4m01s4	23	29	cell	cell	NN
cord-281793-tj4m01s4	23	30	membrane	membrane	NN
cord-281793-tj4m01s4	23	31	,	,	,
cord-281793-tj4m01s4	23	32	inducing	induce	VBG
cord-281793-tj4m01s4	23	33	the	the	DT
cord-281793-tj4m01s4	23	34	conformational	conformational	JJ
cord-281793-tj4m01s4	23	35	change	change	NN
cord-281793-tj4m01s4	23	36	of	of	IN
cord-281793-tj4m01s4	23	37	the	the	DT
cord-281793-tj4m01s4	23	38	S2	S2	NNP
cord-281793-tj4m01s4	23	39	subunit	subunit	NN
cord-281793-tj4m01s4	23	40	,	,	,
cord-281793-tj4m01s4	23	41	which	which	WDT
cord-281793-tj4m01s4	23	42	forms	form	VBZ
cord-281793-tj4m01s4	23	43	a	a	DT
cord-281793-tj4m01s4	23	44	six	six	CD
cord-281793-tj4m01s4	23	45	-	-	HYPH
cord-281793-tj4m01s4	23	46	helix	helix	NN
cord-281793-tj4m01s4	23	47	bundle	bundle	NN
cord-281793-tj4m01s4	23	48	(	(	-LRB-
cord-281793-tj4m01s4	23	49	6-HB	6-hb	CD
cord-281793-tj4m01s4	23	50	)	)	-RRB-
cord-281793-tj4m01s4	23	51	with	with	IN
cord-281793-tj4m01s4	23	52	the	the	DT
cord-281793-tj4m01s4	23	53	HR1	HR1	NNP
cord-281793-tj4m01s4	23	54	and	and	CC
cord-281793-tj4m01s4	23	55	HR2	HR2	NNP
cord-281793-tj4m01s4	23	56	trimers	trimer	NNS
cord-281793-tj4m01s4	23	57	.	.	.
cord-281793-tj4m01s4	24	1	Antibodies	antibody	NNS
cord-281793-tj4m01s4	24	2	(	(	-LRB-
cord-281793-tj4m01s4	24	3	e.g.	e.g.	RB
cord-281793-tj4m01s4	24	4	,	,	,
cord-281793-tj4m01s4	24	5	1A9	1a9	CD
cord-281793-tj4m01s4	24	6	against	against	IN
cord-281793-tj4m01s4	24	7	SARS	SARS	NNP
cord-281793-tj4m01s4	24	8	-	-	HYPH
cord-281793-tj4m01s4	24	9	CoV	CoV	NNP
cord-281793-tj4m01s4	24	10	)	)	-RRB-
cord-281793-tj4m01s4	24	11	that	that	WDT
cord-281793-tj4m01s4	24	12	target	target	VBP
cord-281793-tj4m01s4	24	13	the	the	DT
cord-281793-tj4m01s4	24	14	HR	hr	NN
cord-281793-tj4m01s4	24	15	domains	domain	NNS
cord-281793-tj4m01s4	24	16	might	may	MD
cord-281793-tj4m01s4	24	17	block	block	VB
cord-281793-tj4m01s4	24	18	viral	viral	JJ
cord-281793-tj4m01s4	24	19	fusion	fusion	NN
cord-281793-tj4m01s4	24	20	.	.	.
cord-281793-tj4m01s4	25	1	Ab	ab	NN
cord-281793-tj4m01s4	25	2	,	,	,
cord-281793-tj4m01s4	25	3	antibody	antibody	NN
cord-281793-tj4m01s4	25	4	.	.	.
cord-281793-tj4m01s4	26	1	the	the	DT
cord-281793-tj4m01s4	26	2	bat	bat	NN
cord-281793-tj4m01s4	26	3	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	26	4	RaTG13	ratg13	NN
cord-281793-tj4m01s4	26	5	,	,	,
cord-281793-tj4m01s4	26	6	indicating	indicate	VBG
cord-281793-tj4m01s4	26	7	that	that	IN
cord-281793-tj4m01s4	26	8	the	the	DT
cord-281793-tj4m01s4	26	9	bat	bat	NN
cord-281793-tj4m01s4	26	10	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	26	11	might	may	MD
cord-281793-tj4m01s4	26	12	be	be	VB
cord-281793-tj4m01s4	26	13	the	the	DT
cord-281793-tj4m01s4	26	14	origin	origin	NN
cord-281793-tj4m01s4	26	15	of	of	IN
cord-281793-tj4m01s4	26	16	the	the	DT
cord-281793-tj4m01s4	26	17	SARS	SARS	NNP
cord-281793-tj4m01s4	26	18	-	-	HYPH
cord-281793-tj4m01s4	26	19	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	26	20	[	[	-LRB-
cord-281793-tj4m01s4	26	21	10	10	CD
cord-281793-tj4m01s4	26	22	]	]	-RRB-
cord-281793-tj4m01s4	26	23	.	.	.
cord-281793-tj4m01s4	27	1	Furthermore	furthermore	RB
cord-281793-tj4m01s4	27	2	,	,	,
cord-281793-tj4m01s4	27	3	SARS	SARS	NNP
cord-281793-tj4m01s4	27	4	-	-	HYPH
cord-281793-tj4m01s4	27	5	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	27	6	might	may	MD
cord-281793-tj4m01s4	27	7	be	be	VB
cord-281793-tj4m01s4	27	8	the	the	DT
cord-281793-tj4m01s4	27	9	result	result	NN
cord-281793-tj4m01s4	27	10	of	of	IN
cord-281793-tj4m01s4	27	11	a	a	DT
cord-281793-tj4m01s4	27	12	recombination	recombination	NN
cord-281793-tj4m01s4	27	13	between	between	IN
cord-281793-tj4m01s4	27	14	bat	bat	NN
cord-281793-tj4m01s4	27	15	(	(	-LRB-
cord-281793-tj4m01s4	27	16	RaTG13	RaTG13	NNP
cord-281793-tj4m01s4	27	17	)	)	-RRB-
cord-281793-tj4m01s4	27	18	and	and	CC
cord-281793-tj4m01s4	27	19	pangolin	pangolin	NN
cord-281793-tj4m01s4	27	20	coronaviruses	coronaviruse	NNS
cord-281793-tj4m01s4	27	21	,	,	,
cord-281793-tj4m01s4	27	22	as	as	RB
cord-281793-tj4m01s4	27	23	particularly	particularly	RB
cord-281793-tj4m01s4	27	24	indicated	indicate	VBN
cord-281793-tj4m01s4	27	25	in	in	IN
cord-281793-tj4m01s4	27	26	the	the	DT
cord-281793-tj4m01s4	27	27	S	S	NNP
cord-281793-tj4m01s4	27	28	protein	protein	NN
cord-281793-tj4m01s4	27	29	sequence	sequence	NN
cord-281793-tj4m01s4	27	30	[	[	-LRB-
cord-281793-tj4m01s4	27	31	10	10	CD
cord-281793-tj4m01s4	27	32	]	]	-RRB-
cord-281793-tj4m01s4	27	33	.	.	.
cord-281793-tj4m01s4	28	1	The	the	DT
cord-281793-tj4m01s4	28	2	receptor	receptor	NN
cord-281793-tj4m01s4	28	3	binding	bind	VBG
cord-281793-tj4m01s4	28	4	domain	domain	NN
cord-281793-tj4m01s4	28	5	(	(	-LRB-
cord-281793-tj4m01s4	28	6	RBD	RBD	NNP
cord-281793-tj4m01s4	28	7	)	)	-RRB-
cord-281793-tj4m01s4	28	8	of	of	IN
cord-281793-tj4m01s4	28	9	the	the	DT
cord-281793-tj4m01s4	28	10	SARS	SARS	NNP
cord-281793-tj4m01s4	28	11	-	-	HYPH
cord-281793-tj4m01s4	28	12	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	28	13	S	S	NNP
cord-281793-tj4m01s4	28	14	protein	protein	NN
cord-281793-tj4m01s4	28	15	contains	contain	VBZ
cord-281793-tj4m01s4	28	16	several	several	JJ
cord-281793-tj4m01s4	28	17	novel	novel	JJ
cord-281793-tj4m01s4	28	18	residues	residue	NNS
cord-281793-tj4m01s4	28	19	that	that	WDT
cord-281793-tj4m01s4	28	20	might	may	MD
cord-281793-tj4m01s4	28	21	be	be	VB
cord-281793-tj4m01s4	28	22	introduced	introduce	VBN
cord-281793-tj4m01s4	28	23	through	through	IN
cord-281793-tj4m01s4	28	24	recombination	recombination	NN
cord-281793-tj4m01s4	28	25	with	with	IN
cord-281793-tj4m01s4	28	26	the	the	DT
cord-281793-tj4m01s4	28	27	pangolin	pangolin	NN
cord-281793-tj4m01s4	28	28	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	28	29	,	,	,
cord-281793-tj4m01s4	28	30	indicating	indicate	VBG
cord-281793-tj4m01s4	28	31	a	a	DT
cord-281793-tj4m01s4	28	32	possible	possible	JJ
cord-281793-tj4m01s4	28	33	critical	critical	JJ
cord-281793-tj4m01s4	28	34	step	step	NN
cord-281793-tj4m01s4	28	35	in	in	IN
cord-281793-tj4m01s4	28	36	the	the	DT
cord-281793-tj4m01s4	28	37	evolution	evolution	NN
cord-281793-tj4m01s4	28	38	of	of	IN
cord-281793-tj4m01s4	28	39	the	the	DT
cord-281793-tj4m01s4	28	40	ability	ability	NN
cord-281793-tj4m01s4	28	41	of	of	IN
cord-281793-tj4m01s4	28	42	SARS	SARS	NNP
cord-281793-tj4m01s4	28	43	-	-	HYPH
cord-281793-tj4m01s4	28	44	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	28	45	to	to	TO
cord-281793-tj4m01s4	28	46	infect	infect	VB
cord-281793-tj4m01s4	28	47	humans	human	NNS
cord-281793-tj4m01s4	28	48	[	[	-LRB-
cord-281793-tj4m01s4	28	49	10	10	CD
cord-281793-tj4m01s4	28	50	]	]	-RRB-
cord-281793-tj4m01s4	28	51	.	.	.
cord-281793-tj4m01s4	29	1	The	the	DT
cord-281793-tj4m01s4	29	2	structures	structure	NNS
cord-281793-tj4m01s4	29	3	of	of	IN
cord-281793-tj4m01s4	29	4	SARS	SARS	NNP
cord-281793-tj4m01s4	29	5	-	-	HYPH
cord-281793-tj4m01s4	29	6	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	29	7	S	S	NNP
cord-281793-tj4m01s4	29	8	protein	protein	NN
cord-281793-tj4m01s4	29	9	trimer	trimer	NN
cord-281793-tj4m01s4	29	10	[	[	-LRB-
cord-281793-tj4m01s4	29	11	11	11	CD
cord-281793-tj4m01s4	29	12	]	]	-RRB-
cord-281793-tj4m01s4	29	13	and	and	CC
cord-281793-tj4m01s4	29	14	human	human	JJ
cord-281793-tj4m01s4	29	15	ACE2	ACE2	NNP
cord-281793-tj4m01s4	29	16	[	[	-LRB-
cord-281793-tj4m01s4	29	17	12	12	CD
cord-281793-tj4m01s4	29	18	]	]	-RRB-
cord-281793-tj4m01s4	29	19	have	have	VBP
cord-281793-tj4m01s4	29	20	been	be	VBN
cord-281793-tj4m01s4	29	21	rapidly	rapidly	RB
cord-281793-tj4m01s4	29	22	solved	solve	VBN
cord-281793-tj4m01s4	29	23	using	use	VBG
cord-281793-tj4m01s4	29	24	modern	modern	JJ
cord-281793-tj4m01s4	29	25	cryoelectron	cryoelectron	NN
cord-281793-tj4m01s4	29	26	microscopy	microscopy	NNS
cord-281793-tj4m01s4	29	27	(	(	-LRB-
cord-281793-tj4m01s4	29	28	Cryo	Cryo	NNP
cord-281793-tj4m01s4	29	29	-	-	HYPH
cord-281793-tj4m01s4	29	30	EM	EM	NNP
cord-281793-tj4m01s4	29	31	)	)	-RRB-
cord-281793-tj4m01s4	29	32	.	.	.
cord-281793-tj4m01s4	30	1	The	the	DT
cord-281793-tj4m01s4	30	2	affinity	affinity	NN
cord-281793-tj4m01s4	30	3	of	of	IN
cord-281793-tj4m01s4	30	4	the	the	DT
cord-281793-tj4m01s4	30	5	SARS	SARS	NNP
cord-281793-tj4m01s4	30	6	-	-	HYPH
cord-281793-tj4m01s4	30	7	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	30	8	RBD	RBD	NNP
cord-281793-tj4m01s4	30	9	for	for	IN
cord-281793-tj4m01s4	30	10	human	human	JJ
cord-281793-tj4m01s4	30	11	ACE2	ACE2	NNP
cord-281793-tj4m01s4	30	12	appears	appear	VBZ
cord-281793-tj4m01s4	30	13	stronger	strong	JJR
cord-281793-tj4m01s4	30	14	than	than	IN
cord-281793-tj4m01s4	30	15	the	the	DT
cord-281793-tj4m01s4	30	16	SARS	SARS	NNP
cord-281793-tj4m01s4	30	17	-	-	HYPH
cord-281793-tj4m01s4	30	18	CoV	cov	NN
cord-281793-tj4m01s4	30	19	RBD	RBD	NNP
cord-281793-tj4m01s4	30	20	.	.	.
cord-281793-tj4m01s4	31	1	The	the	DT
cord-281793-tj4m01s4	31	2	structural	structural	JJ
cord-281793-tj4m01s4	31	3	analysis	analysis	NN
cord-281793-tj4m01s4	31	4	of	of	IN
cord-281793-tj4m01s4	31	5	the	the	DT
cord-281793-tj4m01s4	31	6	RBD	RBD	NNP
cord-281793-tj4m01s4	31	7	-	-	HYPH
cord-281793-tj4m01s4	31	8	ACE2	ACE2	NNP
cord-281793-tj4m01s4	31	9	complex	complex	NN
cord-281793-tj4m01s4	31	10	reveals	reveal	VBZ
cord-281793-tj4m01s4	31	11	some	some	DT
cord-281793-tj4m01s4	31	12	of	of	IN
cord-281793-tj4m01s4	31	13	the	the	DT
cord-281793-tj4m01s4	31	14	key	key	JJ
cord-281793-tj4m01s4	31	15	mutations	mutation	NNS
cord-281793-tj4m01s4	31	16	on	on	IN
cord-281793-tj4m01s4	31	17	the	the	DT
cord-281793-tj4m01s4	31	18	RBD	RBD	NNP
cord-281793-tj4m01s4	31	19	,	,	,
cord-281793-tj4m01s4	31	20	such	such	JJ
cord-281793-tj4m01s4	31	21	as	as	IN
cord-281793-tj4m01s4	31	22	F486	F486	NNP
cord-281793-tj4m01s4	31	23	and	and	CC
cord-281793-tj4m01s4	31	24	N501	N501	NNP
cord-281793-tj4m01s4	31	25	,	,	,
cord-281793-tj4m01s4	31	26	that	that	WDT
cord-281793-tj4m01s4	31	27	form	form	VBP
cord-281793-tj4m01s4	31	28	stronger	strong	JJR
cord-281793-tj4m01s4	31	29	contacts	contact	NNS
cord-281793-tj4m01s4	31	30	with	with	IN
cord-281793-tj4m01s4	31	31	human	human	JJ
cord-281793-tj4m01s4	31	32	ACE2	ACE2	NNP
cord-281793-tj4m01s4	31	33	[	[	-LRB-
cord-281793-tj4m01s4	31	34	12	12	CD
cord-281793-tj4m01s4	31	35	]	]	-RRB-
cord-281793-tj4m01s4	31	36	.	.	.
cord-281793-tj4m01s4	32	1	Interestingly	interestingly	RB
cord-281793-tj4m01s4	32	2	,	,	,
cord-281793-tj4m01s4	32	3	these	these	DT
cord-281793-tj4m01s4	32	4	residues	residue	NNS
cord-281793-tj4m01s4	32	5	can	can	MD
cord-281793-tj4m01s4	32	6	be	be	VB
cord-281793-tj4m01s4	32	7	found	find	VBN
cord-281793-tj4m01s4	32	8	in	in	IN
cord-281793-tj4m01s4	32	9	the	the	DT
cord-281793-tj4m01s4	32	10	pangolin	pangolin	NN
cord-281793-tj4m01s4	32	11	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	32	12	[	[	-LRB-
cord-281793-tj4m01s4	32	13	10	10	CD
cord-281793-tj4m01s4	32	14	]	]	-RRB-
cord-281793-tj4m01s4	32	15	.	.	.
cord-281793-tj4m01s4	33	1	In	in	IN
cord-281793-tj4m01s4	33	2	the	the	DT
cord-281793-tj4m01s4	33	3	review	review	NN
cord-281793-tj4m01s4	33	4	paper	paper	NN
cord-281793-tj4m01s4	33	5	from	from	IN
cord-281793-tj4m01s4	33	6	Dr	Dr	NNP
cord-281793-tj4m01s4	33	7	Zhiqiang	Zhiqiang	NNP
cord-281793-tj4m01s4	33	8	An	An	NNP
cord-281793-tj4m01s4	33	9	's	's	POS
cord-281793-tj4m01s4	33	10	group	group	NN
cord-281793-tj4m01s4	33	11	in	in	IN
cord-281793-tj4m01s4	33	12	the	the	DT
cord-281793-tj4m01s4	33	13	University	University	NNP
cord-281793-tj4m01s4	33	14	of	of	IN
cord-281793-tj4m01s4	33	15	Texas	Texas	NNP
cord-281793-tj4m01s4	33	16	Health	Health	NNP
cord-281793-tj4m01s4	33	17	Science	Science	NNP
cord-281793-tj4m01s4	33	18	Center	Center	NNP
cord-281793-tj4m01s4	33	19	at	at	IN
cord-281793-tj4m01s4	33	20	Houston	Houston	NNP
cord-281793-tj4m01s4	33	21	,	,	,
cord-281793-tj4m01s4	33	22	Ku	Ku	NNP
cord-281793-tj4m01s4	33	23	et	et	NNP
cord-281793-tj4m01s4	33	24	al	al	NNP
cord-281793-tj4m01s4	33	25	.	.	.
cord-281793-tj4m01s4	34	1	summarized	summarize	VBD
cord-281793-tj4m01s4	34	2	current	current	JJ
cord-281793-tj4m01s4	34	3	findings	finding	NNS
cord-281793-tj4m01s4	34	4	on	on	IN
cord-281793-tj4m01s4	34	5	the	the	DT
cord-281793-tj4m01s4	34	6	structures	structure	NNS
cord-281793-tj4m01s4	34	7	and	and	CC
cord-281793-tj4m01s4	34	8	functions	function	NNS
cord-281793-tj4m01s4	34	9	of	of	IN
cord-281793-tj4m01s4	34	10	SARS	SARS	NNP
cord-281793-tj4m01s4	34	11	-	-	HYPH
cord-281793-tj4m01s4	34	12	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	34	13	viral	viral	JJ
cord-281793-tj4m01s4	34	14	proteins	protein	NNS
cord-281793-tj4m01s4	34	15	.	.	.
cord-281793-tj4m01s4	35	1	They	-PRON-	PRP
cord-281793-tj4m01s4	35	2	describe	describe	VBP
cord-281793-tj4m01s4	35	3	potential	potential	JJ
cord-281793-tj4m01s4	35	4	strategies	strategy	NNS
cord-281793-tj4m01s4	35	5	for	for	IN
cord-281793-tj4m01s4	35	6	repurposing	repurpose	VBG
cord-281793-tj4m01s4	35	7	drugs	drug	NNS
cord-281793-tj4m01s4	35	8	for	for	IN
cord-281793-tj4m01s4	35	9	the	the	DT
cord-281793-tj4m01s4	35	10	treatment	treatment	NN
cord-281793-tj4m01s4	35	11	of	of	IN
cord-281793-tj4m01s4	35	12	COVID-19	COVID-19	NNP
cord-281793-tj4m01s4	35	13	and	and	CC
cord-281793-tj4m01s4	35	14	the	the	DT
cord-281793-tj4m01s4	35	15	current	current	JJ
cord-281793-tj4m01s4	35	16	development	development	NN
cord-281793-tj4m01s4	35	17	of	of	IN
cord-281793-tj4m01s4	35	18	vaccines	vaccine	NNS
cord-281793-tj4m01s4	35	19	,	,	,
cord-281793-tj4m01s4	35	20	plasma	plasma	NN
cord-281793-tj4m01s4	35	21	therapies	therapy	NNS
cord-281793-tj4m01s4	35	22	,	,	,
cord-281793-tj4m01s4	35	23	and	and	CC
cord-281793-tj4m01s4	35	24	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	35	25	antibodies	antibody	NNS
cord-281793-tj4m01s4	35	26	[	[	-LRB-
cord-281793-tj4m01s4	35	27	4	4	CD
cord-281793-tj4m01s4	35	28	]	]	-RRB-
cord-281793-tj4m01s4	35	29	.	.	.
cord-281793-tj4m01s4	36	1	Their	-PRON-	PRP$
cord-281793-tj4m01s4	36	2	review	review	NN
cord-281793-tj4m01s4	36	3	highlights	highlight	VBZ
cord-281793-tj4m01s4	36	4	the	the	DT
cord-281793-tj4m01s4	36	5	potential	potential	JJ
cord-281793-tj4m01s4	36	6	viral	viral	JJ
cord-281793-tj4m01s4	36	7	targets	target	NNS
cord-281793-tj4m01s4	36	8	,	,	,
cord-281793-tj4m01s4	36	9	screening	screening	NN
cord-281793-tj4m01s4	36	10	methods	method	NNS
cord-281793-tj4m01s4	36	11	,	,	,
cord-281793-tj4m01s4	36	12	in	in	IN
cord-281793-tj4m01s4	36	13	vitro	vitro	FW
cord-281793-tj4m01s4	36	14	and	and	CC
cord-281793-tj4m01s4	36	15	in	in	IN
cord-281793-tj4m01s4	36	16	vivo	vivo	NN
cord-281793-tj4m01s4	36	17	models	model	NNS
cord-281793-tj4m01s4	36	18	,	,	,
cord-281793-tj4m01s4	36	19	as	as	RB
cord-281793-tj4m01s4	36	20	well	well	RB
cord-281793-tj4m01s4	36	21	as	as	IN
cord-281793-tj4m01s4	36	22	discussing	discuss	VBG
cord-281793-tj4m01s4	36	23	potential	potential	JJ
cord-281793-tj4m01s4	36	24	antibody	antibody	NN
cord-281793-tj4m01s4	36	25	-	-	HYPH
cord-281793-tj4m01s4	36	26	dependent	dependent	JJ
cord-281793-tj4m01s4	36	27	enhancement	enhancement	NN
cord-281793-tj4m01s4	36	28	(	(	-LRB-
cord-281793-tj4m01s4	36	29	ADE	ADE	NNP
cord-281793-tj4m01s4	36	30	)	)	-RRB-
cord-281793-tj4m01s4	36	31	and	and	CC
cord-281793-tj4m01s4	36	32	Fc	Fc	NNP
cord-281793-tj4m01s4	36	33	engineering	engineering	NN
cord-281793-tj4m01s4	36	34	for	for	IN
cord-281793-tj4m01s4	36	35	developing	develop	VBG
cord-281793-tj4m01s4	36	36	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	36	37	antibodies	antibody	NNS
cord-281793-tj4m01s4	36	38	for	for	IN
cord-281793-tj4m01s4	36	39	treating	treat	VBG
cord-281793-tj4m01s4	36	40	COVID-19	covid-19	CD
cord-281793-tj4m01s4	36	41	patients	patient	NNS
cord-281793-tj4m01s4	36	42	.	.	.
cord-281793-tj4m01s4	37	1	In	in	IN
cord-281793-tj4m01s4	37	2	particular	particular	JJ
cord-281793-tj4m01s4	37	3	,	,	,
cord-281793-tj4m01s4	37	4	their	-PRON-	PRP$
cord-281793-tj4m01s4	37	5	review	review	NN
cord-281793-tj4m01s4	37	6	describes	describe	VBZ
cord-281793-tj4m01s4	37	7	major	major	JJ
cord-281793-tj4m01s4	37	8	screening	screening	NN
cord-281793-tj4m01s4	37	9	strategies	strategy	NNS
cord-281793-tj4m01s4	37	10	for	for	IN
cord-281793-tj4m01s4	37	11	the	the	DT
cord-281793-tj4m01s4	37	12	discovery	discovery	NN
cord-281793-tj4m01s4	37	13	and	and	CC
cord-281793-tj4m01s4	37	14	development	development	NN
cord-281793-tj4m01s4	37	15	of	of	IN
cord-281793-tj4m01s4	37	16	SARS	SARS	NNP
cord-281793-tj4m01s4	37	17	-	-	HYPH
cord-281793-tj4m01s4	37	18	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	37	19	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	37	20	antibodies	antibody	NNS
cord-281793-tj4m01s4	37	21	and	and	CC
cord-281793-tj4m01s4	37	22	provides	provide	VBZ
cord-281793-tj4m01s4	37	23	several	several	JJ
cord-281793-tj4m01s4	37	24	representative	representative	JJ
cord-281793-tj4m01s4	37	25	examples	example	NNS
cord-281793-tj4m01s4	37	26	using	use	VBG
cord-281793-tj4m01s4	37	27	these	these	DT
cord-281793-tj4m01s4	37	28	methods	method	NNS
cord-281793-tj4m01s4	37	29	.	.	.
cord-281793-tj4m01s4	38	1	Antibody	antibody	NN
cord-281793-tj4m01s4	38	2	sources	source	NNS
cord-281793-tj4m01s4	38	3	may	may	MD
cord-281793-tj4m01s4	38	4	include	include	VB
cord-281793-tj4m01s4	38	5	memory	memory	NN
cord-281793-tj4m01s4	38	6	or	or	CC
cord-281793-tj4m01s4	38	7	plasma	plasma	NN
cord-281793-tj4m01s4	38	8	B	b	NN
cord-281793-tj4m01s4	38	9	cells	cell	NNS
cord-281793-tj4m01s4	38	10	from	from	IN
cord-281793-tj4m01s4	38	11	recovered	recover	VBN
cord-281793-tj4m01s4	38	12	patients	patient	NNS
cord-281793-tj4m01s4	38	13	,	,	,
cord-281793-tj4m01s4	38	14	phage	phage	NN
cord-281793-tj4m01s4	38	15	,	,	,
cord-281793-tj4m01s4	38	16	yeast	yeast	NN
cord-281793-tj4m01s4	38	17	and	and	CC
cord-281793-tj4m01s4	38	18	ribosome	ribosome	NN
cord-281793-tj4m01s4	38	19	libraries	library	NNS
cord-281793-tj4m01s4	38	20	,	,	,
cord-281793-tj4m01s4	38	21	or	or	CC
cord-281793-tj4m01s4	38	22	from	from	IN
cord-281793-tj4m01s4	38	23	mouse	mouse	NN
cord-281793-tj4m01s4	38	24	,	,	,
cord-281793-tj4m01s4	38	25	rabbit	rabbit	NN
cord-281793-tj4m01s4	38	26	,	,	,
cord-281793-tj4m01s4	38	27	monkey	monkey	NN
cord-281793-tj4m01s4	38	28	,	,	,
cord-281793-tj4m01s4	38	29	and	and	CC
cord-281793-tj4m01s4	38	30	llama	llama	NN
cord-281793-tj4m01s4	38	31	immunizations	immunization	NNS
cord-281793-tj4m01s4	38	32	.	.	.
cord-281793-tj4m01s4	39	1	Most	Most	JJS
cord-281793-tj4m01s4	39	2	antibodies	antibody	NNS
cord-281793-tj4m01s4	39	3	are	be	VBP
cord-281793-tj4m01s4	39	4	tested	test	VBN
cord-281793-tj4m01s4	39	5	for	for	IN
cord-281793-tj4m01s4	39	6	their	-PRON-	PRP$
cord-281793-tj4m01s4	39	7	ability	ability	NN
cord-281793-tj4m01s4	39	8	to	to	TO
cord-281793-tj4m01s4	39	9	block	block	VB
cord-281793-tj4m01s4	39	10	S	S	NNP
cord-281793-tj4m01s4	39	11	protein	protein	NN
cord-281793-tj4m01s4	39	12	(	(	-LRB-
cord-281793-tj4m01s4	39	13	or	or	CC
cord-281793-tj4m01s4	39	14	RBD	RBD	NNP
cord-281793-tj4m01s4	39	15	)	)	-RRB-
cord-281793-tj4m01s4	39	16	binding	bind	VBG
cord-281793-tj4m01s4	39	17	to	to	IN
cord-281793-tj4m01s4	39	18	ACE2	ACE2	NNP
cord-281793-tj4m01s4	39	19	and	and	CC
cord-281793-tj4m01s4	39	20	preventing	prevent	VBG
cord-281793-tj4m01s4	39	21	spike	spike	NN
cord-281793-tj4m01s4	39	22	-	-	HYPH
cord-281793-tj4m01s4	39	23	mediated	mediate	VBN
cord-281793-tj4m01s4	39	24	membrane	membrane	NN
cord-281793-tj4m01s4	39	25	fusion	fusion	NN
cord-281793-tj4m01s4	39	26	.	.	.
cord-281793-tj4m01s4	40	1	Antibody	antibody	NN
cord-281793-tj4m01s4	40	2	activity	activity	NN
cord-281793-tj4m01s4	40	3	is	be	VBZ
cord-281793-tj4m01s4	40	4	tested	test	VBN
cord-281793-tj4m01s4	40	5	either	either	CC
cord-281793-tj4m01s4	40	6	by	by	IN
cord-281793-tj4m01s4	40	7	using	use	VBG
cord-281793-tj4m01s4	40	8	a	a	DT
cord-281793-tj4m01s4	40	9	pseudovirus	pseudovirus	NN
cord-281793-tj4m01s4	40	10	-	-	HYPH
cord-281793-tj4m01s4	40	11	based	base	VBN
cord-281793-tj4m01s4	40	12	neutralization	neutralization	NN
cord-281793-tj4m01s4	40	13	assay	assay	NN
cord-281793-tj4m01s4	40	14	or	or	CC
cord-281793-tj4m01s4	40	15	by	by	IN
cord-281793-tj4m01s4	40	16	a	a	DT
cord-281793-tj4m01s4	40	17	live	live	JJ
cord-281793-tj4m01s4	40	18	virus	virus	NN
cord-281793-tj4m01s4	40	19	-	-	HYPH
cord-281793-tj4m01s4	40	20	based	base	VBN
cord-281793-tj4m01s4	40	21	neutralization	neutralization	NN
cord-281793-tj4m01s4	40	22	assay	assay	NN
cord-281793-tj4m01s4	40	23	.	.	.
cord-281793-tj4m01s4	41	1	Animal	animal	NN
cord-281793-tj4m01s4	41	2	models	model	NNS
cord-281793-tj4m01s4	41	3	such	such	JJ
cord-281793-tj4m01s4	41	4	as	as	IN
cord-281793-tj4m01s4	41	5	human	human	JJ
cord-281793-tj4m01s4	41	6	ACE2	ACE2	NNP
cord-281793-tj4m01s4	41	7	transgenic	transgenic	JJ
cord-281793-tj4m01s4	41	8	mice	mouse	NNS
cord-281793-tj4m01s4	41	9	are	be	VBP
cord-281793-tj4m01s4	41	10	also	also	RB
cord-281793-tj4m01s4	41	11	summarized	summarize	VBN
cord-281793-tj4m01s4	41	12	in	in	IN
cord-281793-tj4m01s4	41	13	their	-PRON-	PRP$
cord-281793-tj4m01s4	41	14	review	review	NN
cord-281793-tj4m01s4	41	15	article	article	NN
cord-281793-tj4m01s4	41	16	.	.	.
cord-281793-tj4m01s4	42	1	In	in	IN
cord-281793-tj4m01s4	42	2	the	the	DT
cord-281793-tj4m01s4	42	3	research	research	NN
cord-281793-tj4m01s4	42	4	paper	paper	NN
cord-281793-tj4m01s4	42	5	from	from	IN
cord-281793-tj4m01s4	42	6	Chengdu	Chengdu	NNP
cord-281793-tj4m01s4	42	7	Medical	Medical	NNP
cord-281793-tj4m01s4	42	8	College	College	NNP
cord-281793-tj4m01s4	42	9	and	and	CC
cord-281793-tj4m01s4	42	10	ABLINK	ABLINK	NNP
cord-281793-tj4m01s4	42	11	Biotech	Biotech	NNP
cord-281793-tj4m01s4	42	12	Co.	Co.	NNP
cord-281793-tj4m01s4	42	13	,	,	,
cord-281793-tj4m01s4	42	14	Ltd	Ltd	NNP
cord-281793-tj4m01s4	42	15	in	in	IN
cord-281793-tj4m01s4	42	16	China	China	NNP
cord-281793-tj4m01s4	42	17	,	,	,
cord-281793-tj4m01s4	42	18	Zeng	Zeng	NNP
cord-281793-tj4m01s4	42	19	et	et	FW
cord-281793-tj4m01s4	42	20	al	al	NNP
cord-281793-tj4m01s4	42	21	.	.	.
cord-281793-tj4m01s4	43	1	isolated	isolate	VBN
cord-281793-tj4m01s4	43	2	a	a	DT
cord-281793-tj4m01s4	43	3	human	human	JJ
cord-281793-tj4m01s4	43	4	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	43	5	antibody	antibody	NN
cord-281793-tj4m01s4	43	6	(	(	-LRB-
cord-281793-tj4m01s4	43	7	named	name	VBN
cord-281793-tj4m01s4	43	8	"	"	``
cord-281793-tj4m01s4	43	9	rRBD-15	rrbd-15	CD
cord-281793-tj4m01s4	43	10	"	"	''
cord-281793-tj4m01s4	43	11	)	)	-RRB-
cord-281793-tj4m01s4	43	12	that	that	WDT
cord-281793-tj4m01s4	43	13	inhibits	inhibit	VBZ
cord-281793-tj4m01s4	43	14	the	the	DT
cord-281793-tj4m01s4	43	15	interaction	interaction	NN
cord-281793-tj4m01s4	43	16	of	of	IN
cord-281793-tj4m01s4	43	17	the	the	DT
cord-281793-tj4m01s4	43	18	RBD	RBD	NNP
cord-281793-tj4m01s4	43	19	of	of	IN
cord-281793-tj4m01s4	43	20	SARS	SARS	NNP
cord-281793-tj4m01s4	43	21	-	-	HYPH
cord-281793-tj4m01s4	43	22	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	43	23	and	and	CC
cord-281793-tj4m01s4	43	24	the	the	DT
cord-281793-tj4m01s4	43	25	ACE2	ACE2	NNP
cord-281793-tj4m01s4	43	26	and	and	CC
cord-281793-tj4m01s4	43	27	neutralizes	neutralize	VBZ
cord-281793-tj4m01s4	43	28	the	the	DT
cord-281793-tj4m01s4	43	29	pseudovirus	pseudovirus	JJ
cord-281793-tj4m01s4	43	30	infection	infection	NN
cord-281793-tj4m01s4	43	31	[	[	-LRB-
cord-281793-tj4m01s4	43	32	5	5	CD
cord-281793-tj4m01s4	43	33	]	]	-RRB-
cord-281793-tj4m01s4	43	34	.	.	.
cord-281793-tj4m01s4	44	1	The	the	DT
cord-281793-tj4m01s4	44	2	group	group	NN
cord-281793-tj4m01s4	44	3	used	use	VBD
cord-281793-tj4m01s4	44	4	a	a	DT
cord-281793-tj4m01s4	44	5	competitive	competitive	JJ
cord-281793-tj4m01s4	44	6	screening	screening	NN
cord-281793-tj4m01s4	44	7	strategy	strategy	NN
cord-281793-tj4m01s4	44	8	to	to	TO
cord-281793-tj4m01s4	44	9	isolate	isolate	VB
cord-281793-tj4m01s4	44	10	human	human	JJ
cord-281793-tj4m01s4	44	11	antibodies	antibody	NNS
cord-281793-tj4m01s4	44	12	from	from	IN
cord-281793-tj4m01s4	44	13	a	a	DT
cord-281793-tj4m01s4	44	14	phage	phage	NN
cord-281793-tj4m01s4	44	15	display	display	NN
cord-281793-tj4m01s4	44	16	library	library	NN
cord-281793-tj4m01s4	44	17	.	.	.
cord-281793-tj4m01s4	45	1	In	in	IN
cord-281793-tj4m01s4	45	2	the	the	DT
cord-281793-tj4m01s4	45	3	first	first	JJ
cord-281793-tj4m01s4	45	4	round	round	NN
cord-281793-tj4m01s4	45	5	of	of	IN
cord-281793-tj4m01s4	45	6	phage	phage	NN
cord-281793-tj4m01s4	45	7	panning	panning	NN
cord-281793-tj4m01s4	45	8	,	,	,
cord-281793-tj4m01s4	45	9	they	-PRON-	PRP
cord-281793-tj4m01s4	45	10	followed	follow	VBD
cord-281793-tj4m01s4	45	11	the	the	DT
cord-281793-tj4m01s4	45	12	standard	standard	JJ
cord-281793-tj4m01s4	45	13	procedure	procedure	NN
cord-281793-tj4m01s4	45	14	by	by	IN
cord-281793-tj4m01s4	45	15	screening	screen	VBG
cord-281793-tj4m01s4	45	16	phage	phage	NN
cord-281793-tj4m01s4	45	17	on	on	IN
cord-281793-tj4m01s4	45	18	immobilized	immobilize	VBN
cord-281793-tj4m01s4	45	19	RBD	RBD	NNP
cord-281793-tj4m01s4	45	20	.	.	.
cord-281793-tj4m01s4	46	1	After	after	IN
cord-281793-tj4m01s4	46	2	the	the	DT
cord-281793-tj4m01s4	46	3	first	first	JJ
cord-281793-tj4m01s4	46	4	-	-	HYPH
cord-281793-tj4m01s4	46	5	round	round	NN
cord-281793-tj4m01s4	46	6	enrichment	enrichment	NN
cord-281793-tj4m01s4	46	7	of	of	IN
cord-281793-tj4m01s4	46	8	RBD	RBD	NNP
cord-281793-tj4m01s4	46	9	binders	binder	NNS
cord-281793-tj4m01s4	46	10	,	,	,
cord-281793-tj4m01s4	46	11	in	in	IN
cord-281793-tj4m01s4	46	12	the	the	DT
cord-281793-tj4m01s4	46	13	2nd	2nd	JJ
cord-281793-tj4m01s4	46	14	and	and	CC
cord-281793-tj4m01s4	46	15	3rd	3rd	JJ
cord-281793-tj4m01s4	46	16	rounds	round	NNS
cord-281793-tj4m01s4	46	17	,	,	,
cord-281793-tj4m01s4	46	18	they	-PRON-	PRP
cord-281793-tj4m01s4	46	19	immobilized	immobilize	VBD
cord-281793-tj4m01s4	46	20	ACE2	ACE2	NNP
cord-281793-tj4m01s4	46	21	and	and	CC
cord-281793-tj4m01s4	46	22	added	add	VBD
cord-281793-tj4m01s4	46	23	the	the	DT
cord-281793-tj4m01s4	46	24	mixture	mixture	NN
cord-281793-tj4m01s4	46	25	of	of	IN
cord-281793-tj4m01s4	46	26	free	free	JJ
cord-281793-tj4m01s4	46	27	RBD	RBD	NNP
cord-281793-tj4m01s4	46	28	and	and	CC
cord-281793-tj4m01s4	46	29	a	a	DT
cord-281793-tj4m01s4	46	30	phage	phage	NN
cord-281793-tj4m01s4	46	31	pool	pool	NN
cord-281793-tj4m01s4	46	32	enriched	enrich	VBN
cord-281793-tj4m01s4	46	33	from	from	IN
cord-281793-tj4m01s4	46	34	the	the	DT
cord-281793-tj4m01s4	46	35	1st	1st	JJ
cord-281793-tj4m01s4	46	36	round	round	NN
cord-281793-tj4m01s4	46	37	.	.	.
cord-281793-tj4m01s4	47	1	Phage	phage	NN
cord-281793-tj4m01s4	47	2	that	that	WDT
cord-281793-tj4m01s4	47	3	bind	bind	VBP
cord-281793-tj4m01s4	47	4	RBD	RBD	NNP
cord-281793-tj4m01s4	47	5	at	at	IN
cord-281793-tj4m01s4	47	6	epitopes	epitope	NNS
cord-281793-tj4m01s4	47	7	different	different	JJ
cord-281793-tj4m01s4	47	8	from	from	IN
cord-281793-tj4m01s4	47	9	the	the	DT
cord-281793-tj4m01s4	47	10	ACE2-binding	ace2-binding	NN
cord-281793-tj4m01s4	47	11	site	site	NN
cord-281793-tj4m01s4	47	12	were	be	VBD
cord-281793-tj4m01s4	47	13	captured	capture	VBN
cord-281793-tj4m01s4	47	14	by	by	IN
cord-281793-tj4m01s4	47	15	the	the	DT
cord-281793-tj4m01s4	47	16	immobilized	immobilized	JJ
cord-281793-tj4m01s4	47	17	ACE2	ACE2	NNP
cord-281793-tj4m01s4	47	18	to	to	TO
cord-281793-tj4m01s4	47	19	form	form	VB
cord-281793-tj4m01s4	47	20	a	a	DT
cord-281793-tj4m01s4	47	21	"	"	``
cord-281793-tj4m01s4	47	22	sandwich	sandwich	NN
cord-281793-tj4m01s4	47	23	"	"	''
cord-281793-tj4m01s4	47	24	complex	complex	JJ
cord-281793-tj4m01s4	47	25	.	.	.
cord-281793-tj4m01s4	48	1	Phage	phage	NN
cord-281793-tj4m01s4	48	2	that	that	WDT
cord-281793-tj4m01s4	48	3	competed	compete	VBD
cord-281793-tj4m01s4	48	4	with	with	IN
cord-281793-tj4m01s4	48	5	ACE2	ACE2	NNP
cord-281793-tj4m01s4	48	6	for	for	IN
cord-281793-tj4m01s4	48	7	RBD	RBD	NNP
cord-281793-tj4m01s4	48	8	were	be	VBD
cord-281793-tj4m01s4	48	9	in	in	IN
cord-281793-tj4m01s4	48	10	the	the	DT
cord-281793-tj4m01s4	48	11	supernatant	supernatant	NN
cord-281793-tj4m01s4	48	12	along	along	RB
cord-281793-tj4m01s4	48	13	with	with	IN
cord-281793-tj4m01s4	48	14	presumably	presumably	RB
cord-281793-tj4m01s4	48	15	unknown	unknown	JJ
cord-281793-tj4m01s4	48	16	amounts	amount	NNS
cord-281793-tj4m01s4	48	17	of	of	IN
cord-281793-tj4m01s4	48	18	nonbinders	nonbinder	NNS
cord-281793-tj4m01s4	48	19	or	or	CC
cord-281793-tj4m01s4	48	20	nonspecific	nonspecific	JJ
cord-281793-tj4m01s4	48	21	binders	binder	NNS
cord-281793-tj4m01s4	48	22	.	.	.
cord-281793-tj4m01s4	49	1	The	the	DT
cord-281793-tj4m01s4	49	2	phage	phage	NN
cord-281793-tj4m01s4	49	3	that	that	WDT
cord-281793-tj4m01s4	49	4	bind	bind	VBP
cord-281793-tj4m01s4	49	5	the	the	DT
cord-281793-tj4m01s4	49	6	ACE2	ACE2	NNP
cord-281793-tj4m01s4	49	7	site	site	NN
cord-281793-tj4m01s4	49	8	on	on	IN
cord-281793-tj4m01s4	49	9	the	the	DT
cord-281793-tj4m01s4	49	10	RBD	RBD	NNP
cord-281793-tj4m01s4	49	11	were	be	VBD
cord-281793-tj4m01s4	49	12	then	then	RB
cord-281793-tj4m01s4	49	13	isolated	isolate	VBN
cord-281793-tj4m01s4	49	14	by	by	IN
cord-281793-tj4m01s4	49	15	magnetic	magnetic	JJ
cord-281793-tj4m01s4	49	16	beads	bead	NNS
cord-281793-tj4m01s4	49	17	using	use	VBG
cord-281793-tj4m01s4	49	18	the	the	DT
cord-281793-tj4m01s4	49	19	histidine	histidine	NN
cord-281793-tj4m01s4	49	20	tag	tag	NN
cord-281793-tj4m01s4	49	21	on	on	IN
cord-281793-tj4m01s4	49	22	the	the	DT
cord-281793-tj4m01s4	49	23	RBD	RBD	NNP
cord-281793-tj4m01s4	49	24	.	.	.
cord-281793-tj4m01s4	50	1	The	the	DT
cord-281793-tj4m01s4	50	2	key	key	NN
cord-281793-tj4m01s4	50	3	for	for	IN
cord-281793-tj4m01s4	50	4	success	success	NN
cord-281793-tj4m01s4	50	5	using	use	VBG
cord-281793-tj4m01s4	50	6	this	this	DT
cord-281793-tj4m01s4	50	7	strategy	strategy	NN
cord-281793-tj4m01s4	50	8	is	be	VBZ
cord-281793-tj4m01s4	50	9	the	the	DT
cord-281793-tj4m01s4	50	10	ratio	ratio	NN
cord-281793-tj4m01s4	50	11	of	of	IN
cord-281793-tj4m01s4	50	12	immobilized	immobilize	VBN
cord-281793-tj4m01s4	50	13	ACE2	ACE2	NNP
cord-281793-tj4m01s4	50	14	,	,	,
cord-281793-tj4m01s4	50	15	free	free	JJ
cord-281793-tj4m01s4	50	16	RBD	RBD	NNP
cord-281793-tj4m01s4	50	17	,	,	,
cord-281793-tj4m01s4	50	18	and	and	CC
cord-281793-tj4m01s4	50	19	phage	phage	NN
cord-281793-tj4m01s4	50	20	concentrations	concentration	NNS
cord-281793-tj4m01s4	50	21	in	in	IN
cord-281793-tj4m01s4	50	22	solution	solution	NN
cord-281793-tj4m01s4	50	23	.	.	.
cord-281793-tj4m01s4	51	1	Therefore	therefore	RB
cord-281793-tj4m01s4	51	2	,	,	,
cord-281793-tj4m01s4	51	3	they	-PRON-	PRP
cord-281793-tj4m01s4	51	4	used	use	VBD
cord-281793-tj4m01s4	51	5	a	a	DT
cord-281793-tj4m01s4	51	6	low	low	JJ
cord-281793-tj4m01s4	51	7	concentration	concentration	NN
cord-281793-tj4m01s4	51	8	of	of	IN
cord-281793-tj4m01s4	51	9	RBD	RBD	NNP
cord-281793-tj4m01s4	51	10	(	(	-LRB-
cord-281793-tj4m01s4	51	11	1	1	CD
cord-281793-tj4m01s4	51	12	μg	μg	NN
cord-281793-tj4m01s4	51	13	/	/	SYM
cord-281793-tj4m01s4	51	14	ml	ml	NNP
cord-281793-tj4m01s4	51	15	)	)	-RRB-
cord-281793-tj4m01s4	51	16	close	close	JJ
cord-281793-tj4m01s4	51	17	to	to	IN
cord-281793-tj4m01s4	51	18	the	the	DT
cord-281793-tj4m01s4	51	19	EC	EC	NNP
cord-281793-tj4m01s4	51	20	50	50	CD
cord-281793-tj4m01s4	51	21	value	value	NN
cord-281793-tj4m01s4	51	22	of	of	IN
cord-281793-tj4m01s4	51	23	RBD	rbd	NN
cord-281793-tj4m01s4	51	24	binding	bind	VBG
cord-281793-tj4m01s4	51	25	to	to	IN
cord-281793-tj4m01s4	51	26	ACE2	ACE2	NNP
cord-281793-tj4m01s4	51	27	and	and	CC
cord-281793-tj4m01s4	51	28	a	a	DT
cord-281793-tj4m01s4	51	29	low	low	JJ
cord-281793-tj4m01s4	51	30	concentration	concentration	NN
cord-281793-tj4m01s4	51	31	1	1	CD
cord-281793-tj4m01s4	51	32	×	×	NN
cord-281793-tj4m01s4	51	33	10	10	CD
cord-281793-tj4m01s4	51	34	10	10	CD
cord-281793-tj4m01s4	51	35	pfu	pfu	NN
cord-281793-tj4m01s4	51	36	of	of	IN
cord-281793-tj4m01s4	51	37	the	the	DT
cord-281793-tj4m01s4	51	38	phage	phage	NN
cord-281793-tj4m01s4	51	39	they	-PRON-	PRP
cord-281793-tj4m01s4	51	40	enriched	enrich	VBD
cord-281793-tj4m01s4	51	41	from	from	IN
cord-281793-tj4m01s4	51	42	1st	1st	JJ
cord-281793-tj4m01s4	51	43	round	round	NN
cord-281793-tj4m01s4	51	44	of	of	IN
cord-281793-tj4m01s4	51	45	panning	pan	VBG
cord-281793-tj4m01s4	51	46	on	on	IN
cord-281793-tj4m01s4	51	47	RBD	RBD	NNP
cord-281793-tj4m01s4	51	48	.	.	.
cord-281793-tj4m01s4	52	1	Standard	standard	JJ
cord-281793-tj4m01s4	52	2	phage	phage	NN
cord-281793-tj4m01s4	52	3	panning	panning	NN
cord-281793-tj4m01s4	52	4	protocols	protocol	NNS
cord-281793-tj4m01s4	52	5	used	use	VBN
cord-281793-tj4m01s4	52	6	about	about	RB
cord-281793-tj4m01s4	52	7	100	100	CD
cord-281793-tj4m01s4	52	8	times	time	NNS
cord-281793-tj4m01s4	52	9	more	more	JJR
cord-281793-tj4m01s4	52	10	phage	phage	NN
cord-281793-tj4m01s4	52	11	or	or	CC
cord-281793-tj4m01s4	52	12	about	about	RB
cord-281793-tj4m01s4	52	13	1	1	CD
cord-281793-tj4m01s4	52	14	×	×	CD
cord-281793-tj4m01s4	52	15	10	10	CD
cord-281793-tj4m01s4	52	16	12	12	CD
cord-281793-tj4m01s4	52	17	pfu	pfu	NN
cord-281793-tj4m01s4	52	18	.	.	.
cord-281793-tj4m01s4	53	1	In	in	IN
cord-281793-tj4m01s4	53	2	this	this	DT
cord-281793-tj4m01s4	53	3	way	way	NN
cord-281793-tj4m01s4	53	4	,	,	,
cord-281793-tj4m01s4	53	5	they	-PRON-	PRP
cord-281793-tj4m01s4	53	6	expected	expect	VBD
cord-281793-tj4m01s4	53	7	to	to	TO
cord-281793-tj4m01s4	53	8	reduce	reduce	VB
cord-281793-tj4m01s4	53	9	nonspecific	nonspecific	JJ
cord-281793-tj4m01s4	53	10	binding	binding	NN
cord-281793-tj4m01s4	53	11	of	of	IN
cord-281793-tj4m01s4	53	12	phage	phage	NN
cord-281793-tj4m01s4	53	13	.	.	.
cord-281793-tj4m01s4	54	1	Antibody	Antibody	NNP
cord-281793-tj4m01s4	54	2	Therapeutics	Therapeutics	NNP
cord-281793-tj4m01s4	54	3	,	,	,
cord-281793-tj4m01s4	54	4	2020	2020	CD
cord-281793-tj4m01s4	54	5	111	111	CD
cord-281793-tj4m01s4	54	6	Several	several	JJ
cord-281793-tj4m01s4	54	7	important	important	JJ
cord-281793-tj4m01s4	54	8	questions	question	NNS
cord-281793-tj4m01s4	54	9	are	be	VBP
cord-281793-tj4m01s4	54	10	raised	raise	VBN
cord-281793-tj4m01s4	54	11	in	in	IN
cord-281793-tj4m01s4	54	12	the	the	DT
cord-281793-tj4m01s4	54	13	development	development	NN
cord-281793-tj4m01s4	54	14	of	of	IN
cord-281793-tj4m01s4	54	15	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	54	16	antibodies	antibody	NNS
cord-281793-tj4m01s4	54	17	for	for	IN
cord-281793-tj4m01s4	54	18	treating	treat	VBG
cord-281793-tj4m01s4	54	19	COVID-19	covid-19	NN
cord-281793-tj4m01s4	54	20	.	.	.
cord-281793-tj4m01s4	55	1	Could	Could	MD
cord-281793-tj4m01s4	55	2	such	such	JJ
cord-281793-tj4m01s4	55	3	antibodies	antibody	NNS
cord-281793-tj4m01s4	55	4	be	be	VB
cord-281793-tj4m01s4	55	5	cross	cross	JJ
cord-281793-tj4m01s4	55	6	-	-	JJ
cord-281793-tj4m01s4	55	7	reactive	reactive	JJ
cord-281793-tj4m01s4	55	8	with	with	IN
cord-281793-tj4m01s4	55	9	other	other	JJ
cord-281793-tj4m01s4	55	10	SARS	SARS	NNP
cord-281793-tj4m01s4	55	11	-	-	HYPH
cord-281793-tj4m01s4	55	12	related	relate	VBN
cord-281793-tj4m01s4	55	13	CoVs	CoVs	NNP
cord-281793-tj4m01s4	55	14	(	(	-LRB-
cord-281793-tj4m01s4	55	15	SARSr	SARSr	NNS
cord-281793-tj4m01s4	55	16	-	-	HYPH
cord-281793-tj4m01s4	55	17	CoVs	CoVs	NNP
cord-281793-tj4m01s4	55	18	)	)	-RRB-
cord-281793-tj4m01s4	55	19	?	?	.
cord-281793-tj4m01s4	56	1	Could	Could	MD
cord-281793-tj4m01s4	56	2	such	such	JJ
cord-281793-tj4m01s4	56	3	cross	cross	JJ
cord-281793-tj4m01s4	56	4	-	-	JJ
cord-281793-tj4m01s4	56	5	reactive	reactive	JJ
cord-281793-tj4m01s4	56	6	antibodies	antibody	NNS
cord-281793-tj4m01s4	56	7	have	have	VBP
cord-281793-tj4m01s4	56	8	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	56	9	activities	activity	NNS
cord-281793-tj4m01s4	56	10	for	for	IN
cord-281793-tj4m01s4	56	11	all	all	DT
cord-281793-tj4m01s4	56	12	SARSr	SARSr	NNS
cord-281793-tj4m01s4	56	13	-	-	HYPH
cord-281793-tj4m01s4	56	14	CoVs	CoVs	NNP
cord-281793-tj4m01s4	56	15	?	?	.
cord-281793-tj4m01s4	57	1	What	what	WP
cord-281793-tj4m01s4	57	2	would	would	MD
cord-281793-tj4m01s4	57	3	be	be	VB
cord-281793-tj4m01s4	57	4	ideal	ideal	JJ
cord-281793-tj4m01s4	57	5	targets	target	NNS
cord-281793-tj4m01s4	57	6	or	or	CC
cord-281793-tj4m01s4	57	7	epitopes	epitope	NNS
cord-281793-tj4m01s4	57	8	for	for	IN
cord-281793-tj4m01s4	57	9	cross	cross	NN
cord-281793-tj4m01s4	57	10	-	-	JJ
cord-281793-tj4m01s4	57	11	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	57	12	antibodies	antibody	NNS
cord-281793-tj4m01s4	57	13	?	?	.
cord-281793-tj4m01s4	58	1	Selection	selection	NN
cord-281793-tj4m01s4	58	2	of	of	IN
cord-281793-tj4m01s4	58	3	cross	cross	JJ
cord-281793-tj4m01s4	58	4	-	-	JJ
cord-281793-tj4m01s4	58	5	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	58	6	antibodies	antibody	NNS
cord-281793-tj4m01s4	58	7	would	would	MD
cord-281793-tj4m01s4	58	8	be	be	VB
cord-281793-tj4m01s4	58	9	useful	useful	JJ
cord-281793-tj4m01s4	58	10	for	for	IN
cord-281793-tj4m01s4	58	11	treating	treat	VBG
cord-281793-tj4m01s4	58	12	not	not	RB
cord-281793-tj4m01s4	58	13	only	only	RB
cord-281793-tj4m01s4	58	14	current	current	JJ
cord-281793-tj4m01s4	58	15	COVID-19	covid-19	CD
cord-281793-tj4m01s4	58	16	patients	patient	NNS
cord-281793-tj4m01s4	58	17	but	but	CC
cord-281793-tj4m01s4	58	18	also	also	RB
cord-281793-tj4m01s4	58	19	future	future	JJ
cord-281793-tj4m01s4	58	20	SARSr	SARSr	NNS
cord-281793-tj4m01s4	58	21	-	-	HYPH
cord-281793-tj4m01s4	58	22	CoV	cov	NN
cord-281793-tj4m01s4	58	23	infections	infection	NNS
cord-281793-tj4m01s4	58	24	.	.	.
cord-281793-tj4m01s4	59	1	The	the	DT
cord-281793-tj4m01s4	59	2	RBD	RBD	NNP
cord-281793-tj4m01s4	59	3	of	of	IN
cord-281793-tj4m01s4	59	4	the	the	DT
cord-281793-tj4m01s4	59	5	S	S	NNP
cord-281793-tj4m01s4	59	6	protein	protein	NN
cord-281793-tj4m01s4	59	7	is	be	VBZ
cord-281793-tj4m01s4	59	8	the	the	DT
cord-281793-tj4m01s4	59	9	primary	primary	JJ
cord-281793-tj4m01s4	59	10	target	target	NN
cord-281793-tj4m01s4	59	11	for	for	IN
cord-281793-tj4m01s4	59	12	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	59	13	antibodies	antibody	NNS
cord-281793-tj4m01s4	59	14	.	.	.
cord-281793-tj4m01s4	60	1	Many	many	JJ
cord-281793-tj4m01s4	60	2	known	know	VBN
cord-281793-tj4m01s4	60	3	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	60	4	antibodies	antibody	NNS
cord-281793-tj4m01s4	60	5	,	,	,
cord-281793-tj4m01s4	60	6	including	include	VBG
cord-281793-tj4m01s4	60	7	S230	s230	PRP
cord-281793-tj4m01s4	60	8	,	,	,
cord-281793-tj4m01s4	60	9	m396	m396	NNP
cord-281793-tj4m01s4	60	10	,	,	,
cord-281793-tj4m01s4	60	11	and	and	CC
cord-281793-tj4m01s4	60	12	80R	80R	NNP
cord-281793-tj4m01s4	60	13	,	,	,
cord-281793-tj4m01s4	60	14	are	be	VBP
cord-281793-tj4m01s4	60	15	specific	specific	JJ
cord-281793-tj4m01s4	60	16	for	for	IN
cord-281793-tj4m01s4	60	17	SARS	SARS	NNP
cord-281793-tj4m01s4	60	18	-	-	HYPH
cord-281793-tj4m01s4	60	19	CoV	cov	NN
cord-281793-tj4m01s4	60	20	RBD	RBD	NNP
cord-281793-tj4m01s4	60	21	but	but	CC
cord-281793-tj4m01s4	60	22	fail	fail	VB
cord-281793-tj4m01s4	60	23	to	to	TO
cord-281793-tj4m01s4	60	24	bind	bind	VB
cord-281793-tj4m01s4	60	25	SARS	SARS	NNP
cord-281793-tj4m01s4	60	26	-	-	HYPH
cord-281793-tj4m01s4	60	27	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	60	28	even	even	RB
cord-281793-tj4m01s4	60	29	at	at	IN
cord-281793-tj4m01s4	60	30	the	the	DT
cord-281793-tj4m01s4	60	31	concentration	concentration	NN
cord-281793-tj4m01s4	60	32	up	up	IN
cord-281793-tj4m01s4	60	33	to	to	IN
cord-281793-tj4m01s4	60	34	1	1	CD
cord-281793-tj4m01s4	60	35	μM	μm	CD
cord-281793-tj4m01s4	60	36	[	[	-LRB-
cord-281793-tj4m01s4	60	37	11	11	CD
cord-281793-tj4m01s4	60	38	]	]	-RRB-
cord-281793-tj4m01s4	60	39	.	.	.
cord-281793-tj4m01s4	61	1	Polyclonal	Polyclonal	NNP
cord-281793-tj4m01s4	61	2	antibodies	antibody	NNS
cord-281793-tj4m01s4	61	3	from	from	IN
cord-281793-tj4m01s4	61	4	mice	mouse	NNS
cord-281793-tj4m01s4	61	5	immunized	immunize	VBN
cord-281793-tj4m01s4	61	6	with	with	IN
cord-281793-tj4m01s4	61	7	a	a	DT
cord-281793-tj4m01s4	61	8	stabilized	stabilize	VBN
cord-281793-tj4m01s4	61	9	SARS	SARS	NNP
cord-281793-tj4m01s4	61	10	-	-	HYPH
cord-281793-tj4m01s4	61	11	CoV	CoV	NNP
cord-281793-tj4m01s4	61	12	S	S	NNP
cord-281793-tj4m01s4	61	13	protein	protein	NN
cord-281793-tj4m01s4	61	14	can	can	MD
cord-281793-tj4m01s4	61	15	inhibit	inhibit	VB
cord-281793-tj4m01s4	61	16	SARS	SARS	NNP
cord-281793-tj4m01s4	61	17	-	-	HYPH
cord-281793-tj4m01s4	61	18	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	61	19	entry	entry	NN
cord-281793-tj4m01s4	61	20	into	into	IN
cord-281793-tj4m01s4	61	21	target	target	NN
cord-281793-tj4m01s4	61	22	cells	cell	NNS
cord-281793-tj4m01s4	61	23	.	.	.
cord-281793-tj4m01s4	62	1	This	this	DT
cord-281793-tj4m01s4	62	2	suggests	suggest	VBZ
cord-281793-tj4m01s4	62	3	that	that	IN
cord-281793-tj4m01s4	62	4	immunity	immunity	NN
cord-281793-tj4m01s4	62	5	against	against	IN
cord-281793-tj4m01s4	62	6	one	one	CD
cord-281793-tj4m01s4	62	7	SARSr	SARSr	NNS
cord-281793-tj4m01s4	62	8	-	-	HYPH
cord-281793-tj4m01s4	62	9	CoV	CoV	NNP
cord-281793-tj4m01s4	62	10	can	can	MD
cord-281793-tj4m01s4	62	11	potentially	potentially	RB
cord-281793-tj4m01s4	62	12	provide	provide	VB
cord-281793-tj4m01s4	62	13	protection	protection	NN
cord-281793-tj4m01s4	62	14	against	against	IN
cord-281793-tj4m01s4	62	15	related	relate	VBN
cord-281793-tj4m01s4	62	16	SARS	SARS	NNP
cord-281793-tj4m01s4	62	17	-	-	HYPH
cord-281793-tj4m01s4	62	18	CoV	CoV	NNP
cord-281793-tj4m01s4	62	19	[	[	-LRB-
cord-281793-tj4m01s4	62	20	13	13	CD
cord-281793-tj4m01s4	62	21	]	]	-RRB-
cord-281793-tj4m01s4	62	22	.	.	.
cord-281793-tj4m01s4	63	1	In	in	IN
cord-281793-tj4m01s4	63	2	contrast	contrast	NN
cord-281793-tj4m01s4	63	3	,	,	,
cord-281793-tj4m01s4	63	4	another	another	DT
cord-281793-tj4m01s4	63	5	study	study	NN
cord-281793-tj4m01s4	63	6	showed	show	VBD
cord-281793-tj4m01s4	63	7	that	that	IN
cord-281793-tj4m01s4	63	8	polyclonal	polyclonal	JJ
cord-281793-tj4m01s4	63	9	rabbit	rabbit	NN
cord-281793-tj4m01s4	63	10	anti	anti	NNP
cord-281793-tj4m01s4	63	11	-	-	NNP
cord-281793-tj4m01s4	63	12	SARS	SARS	NNP
cord-281793-tj4m01s4	63	13	-	-	HYPH
cord-281793-tj4m01s4	63	14	CoV	CoV	NNP
cord-281793-tj4m01s4	63	15	S1	s1	NN
cord-281793-tj4m01s4	63	16	antibodies	antibody	NNS
cord-281793-tj4m01s4	63	17	(	(	-LRB-
cord-281793-tj4m01s4	63	18	T62	T62	NNP
cord-281793-tj4m01s4	63	19	)	)	-RRB-
cord-281793-tj4m01s4	63	20	inhibited	inhibit	VBN
cord-281793-tj4m01s4	63	21	entry	entry	NN
cord-281793-tj4m01s4	63	22	of	of	IN
cord-281793-tj4m01s4	63	23	SARS	SARS	NNP
cord-281793-tj4m01s4	63	24	-	-	HYPH
cord-281793-tj4m01s4	63	25	CoV	CoV	NNP
cord-281793-tj4m01s4	63	26	,	,	,
cord-281793-tj4m01s4	63	27	but	but	CC
cord-281793-tj4m01s4	63	28	not	not	RB
cord-281793-tj4m01s4	63	29	SARS	SARS	NNP
cord-281793-tj4m01s4	63	30	-	-	HYPH
cord-281793-tj4m01s4	63	31	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	63	32	pseudovirus	pseudovirus	NN
cord-281793-tj4m01s4	63	33	[	[	-LRB-
cord-281793-tj4m01s4	63	34	14	14	CD
cord-281793-tj4m01s4	63	35	]	]	-RRB-
cord-281793-tj4m01s4	63	36	.	.	.
cord-281793-tj4m01s4	64	1	In	in	IN
cord-281793-tj4m01s4	64	2	addition	addition	NN
cord-281793-tj4m01s4	64	3	,	,	,
cord-281793-tj4m01s4	64	4	sera	sera	NNP
cord-281793-tj4m01s4	64	5	from	from	IN
cord-281793-tj4m01s4	64	6	recovered	recover	VBN
cord-281793-tj4m01s4	64	7	SARS	SARS	NNP
cord-281793-tj4m01s4	64	8	and	and	CC
cord-281793-tj4m01s4	64	9	COVID-19	COVID-19	NNP
cord-281793-tj4m01s4	64	10	patients	patient	NNS
cord-281793-tj4m01s4	64	11	show	show	VBP
cord-281793-tj4m01s4	64	12	only	only	RB
cord-281793-tj4m01s4	64	13	modest	modest	JJ
cord-281793-tj4m01s4	64	14	cross	cross	NN
cord-281793-tj4m01s4	64	15	-	-	NN
cord-281793-tj4m01s4	64	16	neutralization	neutralization	NN
cord-281793-tj4m01s4	64	17	,	,	,
cord-281793-tj4m01s4	64	18	suggesting	suggest	VBG
cord-281793-tj4m01s4	64	19	that	that	IN
cord-281793-tj4m01s4	64	20	recovery	recovery	NN
cord-281793-tj4m01s4	64	21	from	from	IN
cord-281793-tj4m01s4	64	22	one	one	CD
cord-281793-tj4m01s4	64	23	SARSr	SARSr	NNP
cord-281793-tj4m01s4	64	24	-	-	HYPH
cord-281793-tj4m01s4	64	25	CoV	cov	NN
cord-281793-tj4m01s4	64	26	infection	infection	NN
cord-281793-tj4m01s4	64	27	might	may	MD
cord-281793-tj4m01s4	64	28	not	not	RB
cord-281793-tj4m01s4	64	29	protect	protect	VB
cord-281793-tj4m01s4	64	30	against	against	IN
cord-281793-tj4m01s4	64	31	the	the	DT
cord-281793-tj4m01s4	64	32	other	other	JJ
cord-281793-tj4m01s4	64	33	.	.	.
cord-281793-tj4m01s4	65	1	A	a	DT
cord-281793-tj4m01s4	65	2	recent	recent	JJ
cord-281793-tj4m01s4	65	3	report	report	NN
cord-281793-tj4m01s4	65	4	showed	show	VBD
cord-281793-tj4m01s4	65	5	that	that	IN
cord-281793-tj4m01s4	65	6	none	none	NN
cord-281793-tj4m01s4	65	7	of	of	IN
cord-281793-tj4m01s4	65	8	the	the	DT
cord-281793-tj4m01s4	65	9	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	65	10	antibodies	antibody	NNS
cord-281793-tj4m01s4	65	11	isolated	isolate	VBN
cord-281793-tj4m01s4	65	12	from	from	IN
cord-281793-tj4m01s4	65	13	SARS	SARS	NNP
cord-281793-tj4m01s4	65	14	-	-	HYPH
cord-281793-tj4m01s4	65	15	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	65	16	infected	infect	VBN
cord-281793-tj4m01s4	65	17	individuals	individual	NNS
cord-281793-tj4m01s4	65	18	by	by	IN
cord-281793-tj4m01s4	65	19	single	single	JJ
cord-281793-tj4m01s4	65	20	B	b	NN
cord-281793-tj4m01s4	65	21	-	-	HYPH
cord-281793-tj4m01s4	65	22	cell	cell	NN
cord-281793-tj4m01s4	65	23	sorting	sorting	NN
cord-281793-tj4m01s4	65	24	were	be	VBD
cord-281793-tj4m01s4	65	25	cross	cross	JJ
cord-281793-tj4m01s4	65	26	-	-	JJ
cord-281793-tj4m01s4	65	27	reactive	reactive	JJ
cord-281793-tj4m01s4	65	28	with	with	IN
cord-281793-tj4m01s4	65	29	the	the	DT
cord-281793-tj4m01s4	65	30	RBD	RBD	NNP
cord-281793-tj4m01s4	65	31	of	of	IN
cord-281793-tj4m01s4	65	32	SARS	SARS	NNP
cord-281793-tj4m01s4	65	33	-	-	HYPH
cord-281793-tj4m01s4	65	34	CoV	CoV	NNP
cord-281793-tj4m01s4	65	35	[	[	-LRB-
cord-281793-tj4m01s4	65	36	15	15	CD
cord-281793-tj4m01s4	65	37	]	]	-RRB-
cord-281793-tj4m01s4	65	38	.	.	.
cord-281793-tj4m01s4	66	1	In	in	IN
cord-281793-tj4m01s4	66	2	a	a	DT
cord-281793-tj4m01s4	66	3	research	research	NN
cord-281793-tj4m01s4	66	4	article	article	NN
cord-281793-tj4m01s4	66	5	published	publish	VBN
cord-281793-tj4m01s4	66	6	in	in	IN
cord-281793-tj4m01s4	66	7	our	-PRON-	PRP$
cord-281793-tj4m01s4	66	8	journal	journal	NN
cord-281793-tj4m01s4	66	9	,	,	,
cord-281793-tj4m01s4	66	10	Zeng	Zeng	NNP
cord-281793-tj4m01s4	66	11	et	et	NNP
cord-281793-tj4m01s4	66	12	al	al	NNP
cord-281793-tj4m01s4	66	13	.	.	NNP
cord-281793-tj4m01s4	66	14	did	do	VBD
cord-281793-tj4m01s4	66	15	not	not	RB
cord-281793-tj4m01s4	66	16	test	test	VB
cord-281793-tj4m01s4	66	17	the	the	DT
cord-281793-tj4m01s4	66	18	cross	cross	NN
cord-281793-tj4m01s4	66	19	-	-	NN
cord-281793-tj4m01s4	66	20	reactivity	reactivity	NN
cord-281793-tj4m01s4	66	21	of	of	IN
cord-281793-tj4m01s4	66	22	the	the	DT
cord-281793-tj4m01s4	66	23	rRBD-15	rRBD-15	NNP
cord-281793-tj4m01s4	66	24	human	human	JJ
cord-281793-tj4m01s4	66	25	antibody	antibody	NN
cord-281793-tj4m01s4	66	26	for	for	IN
cord-281793-tj4m01s4	66	27	SARS	SARS	NNP
cord-281793-tj4m01s4	66	28	-	-	HYPH
cord-281793-tj4m01s4	66	29	CoV	cov	NN
cord-281793-tj4m01s4	66	30	RBD	RBD	NNP
cord-281793-tj4m01s4	66	31	[	[	-LRB-
cord-281793-tj4m01s4	66	32	5	5	CD
cord-281793-tj4m01s4	66	33	]	]	-RRB-
cord-281793-tj4m01s4	66	34	.	.	.
cord-281793-tj4m01s4	67	1	In	in	IN
cord-281793-tj4m01s4	67	2	the	the	DT
cord-281793-tj4m01s4	67	3	review	review	NN
cord-281793-tj4m01s4	67	4	article	article	NN
cord-281793-tj4m01s4	67	5	,	,	,
cord-281793-tj4m01s4	67	6	Ku	Ku	NNP
cord-281793-tj4m01s4	67	7	et	et	NNP
cord-281793-tj4m01s4	67	8	al	al	NNP
cord-281793-tj4m01s4	67	9	.	.	NNP
cord-281793-tj4m01s4	67	10	discusses	discuss	VBZ
cord-281793-tj4m01s4	67	11	two	two	CD
cord-281793-tj4m01s4	67	12	unique	unique	JJ
cord-281793-tj4m01s4	67	13	cross	cross	JJ
cord-281793-tj4m01s4	67	14	-	-	JJ
cord-281793-tj4m01s4	67	15	reactive	reactive	JJ
cord-281793-tj4m01s4	67	16	antibodies	antibody	NNS
cord-281793-tj4m01s4	67	17	,	,	,
cord-281793-tj4m01s4	67	18	CR3022	cr3022	NN
cord-281793-tj4m01s4	67	19	and	and	CC
cord-281793-tj4m01s4	67	20	47D11	47d11	NN
cord-281793-tj4m01s4	67	21	,	,	,
cord-281793-tj4m01s4	67	22	which	which	WDT
cord-281793-tj4m01s4	67	23	bind	bind	VBP
cord-281793-tj4m01s4	67	24	highly	highly	RB
cord-281793-tj4m01s4	67	25	conserved	conserved	JJ
cord-281793-tj4m01s4	67	26	epitopes	epitope	NNS
cord-281793-tj4m01s4	67	27	in	in	IN
cord-281793-tj4m01s4	67	28	the	the	DT
cord-281793-tj4m01s4	67	29	RBD	RBD	NNP
cord-281793-tj4m01s4	67	30	[	[	-LRB-
cord-281793-tj4m01s4	67	31	4	4	CD
cord-281793-tj4m01s4	67	32	]	]	-RRB-
cord-281793-tj4m01s4	67	33	.	.	.
cord-281793-tj4m01s4	68	1	CR3022	cr3022	NN
cord-281793-tj4m01s4	68	2	is	be	VBZ
cord-281793-tj4m01s4	68	3	an	an	DT
cord-281793-tj4m01s4	68	4	antibody	antibody	NN
cord-281793-tj4m01s4	68	5	that	that	WDT
cord-281793-tj4m01s4	68	6	binds	bind	VBZ
cord-281793-tj4m01s4	68	7	both	both	DT
cord-281793-tj4m01s4	68	8	SARS	SARS	NNP
cord-281793-tj4m01s4	68	9	-	-	HYPH
cord-281793-tj4m01s4	68	10	CoV	CoV	NNP
cord-281793-tj4m01s4	68	11	and	and	CC
cord-281793-tj4m01s4	68	12	SARS	SARS	NNP
cord-281793-tj4m01s4	68	13	-	-	HYPH
cord-281793-tj4m01s4	68	14	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	68	15	RBDs	rbds	NN
cord-281793-tj4m01s4	68	16	,	,	,
cord-281793-tj4m01s4	68	17	but	but	CC
cord-281793-tj4m01s4	68	18	it	-PRON-	PRP
cord-281793-tj4m01s4	68	19	can	can	MD
cord-281793-tj4m01s4	68	20	not	not	RB
cord-281793-tj4m01s4	68	21	neutralize	neutralize	VB
cord-281793-tj4m01s4	68	22	SARS	SARS	NNP
cord-281793-tj4m01s4	68	23	-	-	HYPH
cord-281793-tj4m01s4	68	24	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	68	25	as	as	IN
cord-281793-tj4m01s4	68	26	it	-PRON-	PRP
cord-281793-tj4m01s4	68	27	does	do	VBZ
cord-281793-tj4m01s4	68	28	SARS	SARS	NNP
cord-281793-tj4m01s4	68	29	-	-	HYPH
cord-281793-tj4m01s4	68	30	CoV	CoV	NNP
cord-281793-tj4m01s4	68	31	[	[	-LRB-
cord-281793-tj4m01s4	68	32	16	16	CD
cord-281793-tj4m01s4	68	33	]	]	-RRB-
cord-281793-tj4m01s4	68	34	.	.	.
cord-281793-tj4m01s4	69	1	More	more	RBR
cord-281793-tj4m01s4	69	2	recently	recently	RB
cord-281793-tj4m01s4	69	3	,	,	,
cord-281793-tj4m01s4	69	4	Wang	Wang	NNP
cord-281793-tj4m01s4	69	5	et	et	NNP
cord-281793-tj4m01s4	69	6	al	al	NNP
cord-281793-tj4m01s4	69	7	.	.	NNP
cord-281793-tj4m01s4	69	8	identified	identify	VBD
cord-281793-tj4m01s4	69	9	the	the	DT
cord-281793-tj4m01s4	69	10	47D11	47d11	CD
cord-281793-tj4m01s4	69	11	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	69	12	antibody	antibody	NN
cord-281793-tj4m01s4	69	13	that	that	WDT
cord-281793-tj4m01s4	69	14	can	can	MD
cord-281793-tj4m01s4	69	15	neutralize	neutralize	VB
cord-281793-tj4m01s4	69	16	both	both	DT
cord-281793-tj4m01s4	69	17	SARS	SARS	NNP
cord-281793-tj4m01s4	69	18	-	-	HYPH
cord-281793-tj4m01s4	69	19	CoV	CoV	NNP
cord-281793-tj4m01s4	69	20	and	and	CC
cord-281793-tj4m01s4	69	21	SARS	SARS	NNP
cord-281793-tj4m01s4	69	22	-	-	HYPH
cord-281793-tj4m01s4	69	23	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	69	24	infection	infection	NN
cord-281793-tj4m01s4	69	25	[	[	-LRB-
cord-281793-tj4m01s4	69	26	17	17	CD
cord-281793-tj4m01s4	69	27	]	]	-RRB-
cord-281793-tj4m01s4	69	28	.	.	.
cord-281793-tj4m01s4	70	1	The	the	DT
cord-281793-tj4m01s4	70	2	47D11	47d11	JJ
cord-281793-tj4m01s4	70	3	antibody	antibody	NN
cord-281793-tj4m01s4	70	4	was	be	VBD
cord-281793-tj4m01s4	70	5	isolated	isolate	VBN
cord-281793-tj4m01s4	70	6	from	from	IN
cord-281793-tj4m01s4	70	7	transgenic	transgenic	JJ
cord-281793-tj4m01s4	70	8	mice	mouse	NNS
cord-281793-tj4m01s4	70	9	immunized	immunize	VBN
cord-281793-tj4m01s4	70	10	sequentially	sequentially	RB
cord-281793-tj4m01s4	70	11	with	with	IN
cord-281793-tj4m01s4	70	12	purified	purify	VBN
cord-281793-tj4m01s4	70	13	S	s	NN
cord-281793-tj4m01s4	70	14	proteins	protein	NNS
cord-281793-tj4m01s4	70	15	of	of	IN
cord-281793-tj4m01s4	70	16	different	different	JJ
cord-281793-tj4m01s4	70	17	coronaviruses	coronaviruse	NNS
cord-281793-tj4m01s4	71	1	(	(	-LRB-
cord-281793-tj4m01s4	71	2	HCoV	HCoV	NNP
cord-281793-tj4m01s4	71	3	-	-	HYPH
cord-281793-tj4m01s4	71	4	OC43	OC43	NNP
cord-281793-tj4m01s4	71	5	,	,	,
cord-281793-tj4m01s4	71	6	SARS	SARS	NNP
cord-281793-tj4m01s4	71	7	-	-	HYPH
cord-281793-tj4m01s4	71	8	CoV	CoV	NNP
cord-281793-tj4m01s4	71	9	,	,	,
cord-281793-tj4m01s4	71	10	and	and	CC
cord-281793-tj4m01s4	71	11	MERS	MERS	NNP
cord-281793-tj4m01s4	71	12	-	-	HYPH
cord-281793-tj4m01s4	71	13	CoV	CoV	NNP
cord-281793-tj4m01s4	71	14	)	)	-RRB-
cord-281793-tj4m01s4	71	15	.	.	.
cord-281793-tj4m01s4	72	1	The	the	DT
cord-281793-tj4m01s4	72	2	transgenic	transgenic	JJ
cord-281793-tj4m01s4	72	3	mice	mouse	NNS
cord-281793-tj4m01s4	72	4	produce	produce	VBP
cord-281793-tj4m01s4	72	5	chimeric	chimeric	JJ
cord-281793-tj4m01s4	72	6	immunoglobulins	immunoglobulin	NNS
cord-281793-tj4m01s4	72	7	with	with	IN
cord-281793-tj4m01s4	72	8	human	human	JJ
cord-281793-tj4m01s4	72	9	variable	variable	JJ
cord-281793-tj4m01s4	72	10	regions	region	NNS
cord-281793-tj4m01s4	72	11	and	and	CC
cord-281793-tj4m01s4	72	12	rodent	rodent	NN
cord-281793-tj4m01s4	72	13	constant	constant	JJ
cord-281793-tj4m01s4	72	14	regions	region	NNS
cord-281793-tj4m01s4	72	15	.	.	.
cord-281793-tj4m01s4	73	1	Four	four	CD
cord-281793-tj4m01s4	73	2	of	of	IN
cord-281793-tj4m01s4	73	3	51	51	CD
cord-281793-tj4m01s4	73	4	antibodies	antibody	NNS
cord-281793-tj4m01s4	73	5	specific	specific	JJ
cord-281793-tj4m01s4	73	6	for	for	IN
cord-281793-tj4m01s4	73	7	the	the	DT
cord-281793-tj4m01s4	73	8	S	S	NNP
cord-281793-tj4m01s4	73	9	protein	protein	NN
cord-281793-tj4m01s4	73	10	of	of	IN
cord-281793-tj4m01s4	73	11	SARS	SARS	NNP
cord-281793-tj4m01s4	73	12	-	-	HYPH
cord-281793-tj4m01s4	73	13	CoV	CoV	NNP
cord-281793-tj4m01s4	73	14	show	show	NNP
cord-281793-tj4m01s4	73	15	cross	cross	NN
cord-281793-tj4m01s4	73	16	-	-	NN
cord-281793-tj4m01s4	73	17	reactivity	reactivity	NN
cord-281793-tj4m01s4	73	18	with	with	IN
cord-281793-tj4m01s4	73	19	the	the	DT
cord-281793-tj4m01s4	73	20	S1	S1	NNP
cord-281793-tj4m01s4	73	21	subunit	subunit	NN
cord-281793-tj4m01s4	73	22	of	of	IN
cord-281793-tj4m01s4	73	23	SARS	SARS	NNP
cord-281793-tj4m01s4	73	24	-	-	HYPH
cord-281793-tj4m01s4	73	25	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	73	26	.	.	.
cord-281793-tj4m01s4	74	1	Among	among	IN
cord-281793-tj4m01s4	74	2	them	-PRON-	PRP
cord-281793-tj4m01s4	74	3	,	,	,
cord-281793-tj4m01s4	74	4	the	the	DT
cord-281793-tj4m01s4	74	5	47D11	47d11	JJ
cord-281793-tj4m01s4	74	6	antibody	antibody	NN
cord-281793-tj4m01s4	74	7	exhibits	exhibit	VBZ
cord-281793-tj4m01s4	74	8	the	the	DT
cord-281793-tj4m01s4	74	9	cross	cross	NN
cord-281793-tj4m01s4	74	10	-	-	JJ
cord-281793-tj4m01s4	74	11	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	74	12	activity	activity	NN
cord-281793-tj4m01s4	74	13	of	of	IN
cord-281793-tj4m01s4	74	14	SARS	SARS	NNP
cord-281793-tj4m01s4	74	15	-	-	HYPH
cord-281793-tj4m01s4	74	16	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	74	17	and	and	CC
cord-281793-tj4m01s4	74	18	SARS	SARS	NNP
cord-281793-tj4m01s4	74	19	-	-	HYPH
cord-281793-tj4m01s4	74	20	CoV	CoV	NNP
cord-281793-tj4m01s4	74	21	in	in	IN
cord-281793-tj4m01s4	74	22	cell	cell	NN
cord-281793-tj4m01s4	74	23	culture	culture	NN
cord-281793-tj4m01s4	74	24	.	.	.
cord-281793-tj4m01s4	75	1	Interestingly	interestingly	RB
cord-281793-tj4m01s4	75	2	,	,	,
cord-281793-tj4m01s4	75	3	47D11	47d11	NN
cord-281793-tj4m01s4	75	4	binds	bind	VBZ
cord-281793-tj4m01s4	75	5	the	the	DT
cord-281793-tj4m01s4	75	6	RBD	RBD	NNP
cord-281793-tj4m01s4	75	7	but	but	CC
cord-281793-tj4m01s4	75	8	does	do	VBZ
cord-281793-tj4m01s4	75	9	not	not	RB
cord-281793-tj4m01s4	75	10	block	block	VB
cord-281793-tj4m01s4	75	11	the	the	DT
cord-281793-tj4m01s4	75	12	interaction	interaction	NN
cord-281793-tj4m01s4	75	13	of	of	IN
cord-281793-tj4m01s4	75	14	RBD	RBD	NNP
cord-281793-tj4m01s4	75	15	and	and	CC
cord-281793-tj4m01s4	75	16	ACE2	ACE2	NNP
cord-281793-tj4m01s4	75	17	,	,	,
cord-281793-tj4m01s4	75	18	indicating	indicate	VBG
cord-281793-tj4m01s4	75	19	that	that	IN
cord-281793-tj4m01s4	75	20	47D11	47d11	NN
cord-281793-tj4m01s4	75	21	might	may	MD
cord-281793-tj4m01s4	75	22	bind	bind	VB
cord-281793-tj4m01s4	75	23	a	a	DT
cord-281793-tj4m01s4	75	24	highly	highly	RB
cord-281793-tj4m01s4	75	25	conserved	conserve	VBN
cord-281793-tj4m01s4	75	26	epitope	epitope	NN
cord-281793-tj4m01s4	75	27	of	of	IN
cord-281793-tj4m01s4	75	28	the	the	DT
cord-281793-tj4m01s4	75	29	RBD	RBD	NNP
cord-281793-tj4m01s4	75	30	distinct	distinct	JJ
cord-281793-tj4m01s4	75	31	from	from	IN
cord-281793-tj4m01s4	75	32	the	the	DT
cord-281793-tj4m01s4	75	33	ACE2	ACE2	NNP
cord-281793-tj4m01s4	75	34	binding	binding	NN
cord-281793-tj4m01s4	75	35	site	site	NN
cord-281793-tj4m01s4	75	36	.	.	.
cord-281793-tj4m01s4	76	1	Previous	previous	JJ
cord-281793-tj4m01s4	76	2	studies	study	NNS
cord-281793-tj4m01s4	76	3	indicate	indicate	VBP
cord-281793-tj4m01s4	76	4	that	that	IN
cord-281793-tj4m01s4	76	5	SARS	SARS	NNP
cord-281793-tj4m01s4	76	6	-	-	HYPH
cord-281793-tj4m01s4	76	7	CoV	CoV	NNP
cord-281793-tj4m01s4	76	8	RBD	RBD	NNP
cord-281793-tj4m01s4	76	9	antibodies	antibody	NNS
cord-281793-tj4m01s4	76	10	that	that	WDT
cord-281793-tj4m01s4	76	11	block	block	VBP
cord-281793-tj4m01s4	76	12	the	the	DT
cord-281793-tj4m01s4	76	13	interaction	interaction	NN
cord-281793-tj4m01s4	76	14	of	of	IN
cord-281793-tj4m01s4	76	15	the	the	DT
cord-281793-tj4m01s4	76	16	RBD	RBD	NNP
cord-281793-tj4m01s4	76	17	and	and	CC
cord-281793-tj4m01s4	76	18	ACE2	ACE2	NNP
cord-281793-tj4m01s4	76	19	are	be	VBP
cord-281793-tj4m01s4	76	20	not	not	RB
cord-281793-tj4m01s4	76	21	cross	cross	JJ
cord-281793-tj4m01s4	76	22	-	-	JJ
cord-281793-tj4m01s4	76	23	reactive	reactive	JJ
cord-281793-tj4m01s4	76	24	with	with	IN
cord-281793-tj4m01s4	76	25	SARS	SARS	NNP
cord-281793-tj4m01s4	76	26	-	-	HYPH
cord-281793-tj4m01s4	76	27	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	76	28	RBD	RBD	NNP
cord-281793-tj4m01s4	76	29	[	[	-LRB-
cord-281793-tj4m01s4	76	30	11	11	CD
cord-281793-tj4m01s4	76	31	]	]	-RRB-
cord-281793-tj4m01s4	76	32	.	.	.
cord-281793-tj4m01s4	77	1	CR3022	cr3022	NN
cord-281793-tj4m01s4	77	2	also	also	RB
cord-281793-tj4m01s4	77	3	binds	bind	VBZ
cord-281793-tj4m01s4	77	4	a	a	DT
cord-281793-tj4m01s4	77	5	highly	highly	RB
cord-281793-tj4m01s4	77	6	conserved	conserve	VBN
cord-281793-tj4m01s4	77	7	epitope	epitope	NN
cord-281793-tj4m01s4	77	8	on	on	IN
cord-281793-tj4m01s4	77	9	the	the	DT
cord-281793-tj4m01s4	77	10	RBD	RBD	NNP
cord-281793-tj4m01s4	77	11	and	and	CC
cord-281793-tj4m01s4	77	12	binds	bind	VBZ
cord-281793-tj4m01s4	77	13	both	both	DT
cord-281793-tj4m01s4	77	14	SARS	SARS	NNP
cord-281793-tj4m01s4	77	15	-	-	HYPH
cord-281793-tj4m01s4	77	16	CoV	CoV	NNP
cord-281793-tj4m01s4	77	17	and	and	CC
cord-281793-tj4m01s4	77	18	SARS	SARS	NNP
cord-281793-tj4m01s4	77	19	-	-	HYPH
cord-281793-tj4m01s4	77	20	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	77	21	RBDs	RBDs	.
cord-281793-tj4m01s4	77	22	[	[	-LRB-
cord-281793-tj4m01s4	77	23	16	16	CD
cord-281793-tj4m01s4	77	24	]	]	-RRB-
cord-281793-tj4m01s4	77	25	,	,	,
cord-281793-tj4m01s4	77	26	but	but	CC
cord-281793-tj4m01s4	77	27	unlike	unlike	IN
cord-281793-tj4m01s4	77	28	47D11	47d11	CD
cord-281793-tj4m01s4	77	29	,	,	,
cord-281793-tj4m01s4	77	30	it	-PRON-	PRP
cord-281793-tj4m01s4	77	31	does	do	VBZ
cord-281793-tj4m01s4	77	32	not	not	RB
cord-281793-tj4m01s4	77	33	have	have	VB
cord-281793-tj4m01s4	77	34	the	the	DT
cord-281793-tj4m01s4	77	35	cross	cross	NN
cord-281793-tj4m01s4	77	36	-	-	JJ
cord-281793-tj4m01s4	77	37	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	77	38	activity	activity	NN
cord-281793-tj4m01s4	77	39	against	against	IN
cord-281793-tj4m01s4	77	40	SARS	SARS	NNP
cord-281793-tj4m01s4	77	41	-	-	HYPH
cord-281793-tj4m01s4	77	42	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	77	43	.	.	.
cord-281793-tj4m01s4	78	1	The	the	DT
cord-281793-tj4m01s4	78	2	structure	structure	NN
cord-281793-tj4m01s4	78	3	complex	complex	NN
cord-281793-tj4m01s4	78	4	of	of	IN
cord-281793-tj4m01s4	78	5	47D11	47d11	CD
cord-281793-tj4m01s4	78	6	and	and	CC
cord-281793-tj4m01s4	78	7	the	the	DT
cord-281793-tj4m01s4	78	8	RBD	RBD	NNP
cord-281793-tj4m01s4	78	9	(	(	-LRB-
cord-281793-tj4m01s4	78	10	or	or	CC
cord-281793-tj4m01s4	78	11	the	the	DT
cord-281793-tj4m01s4	78	12	S1	S1	NNP
cord-281793-tj4m01s4	78	13	/	/	SYM
cord-281793-tj4m01s4	78	14	S	S	NNP
cord-281793-tj4m01s4	78	15	protein	protein	NN
cord-281793-tj4m01s4	78	16	)	)	-RRB-
cord-281793-tj4m01s4	78	17	would	would	MD
cord-281793-tj4m01s4	78	18	reveal	reveal	VB
cord-281793-tj4m01s4	78	19	a	a	DT
cord-281793-tj4m01s4	78	20	novel	novel	NN
cord-281793-tj4m01s4	78	21	conserved	conserve	VBN
cord-281793-tj4m01s4	78	22	site	site	NN
cord-281793-tj4m01s4	78	23	on	on	IN
cord-281793-tj4m01s4	78	24	the	the	DT
cord-281793-tj4m01s4	78	25	RBD	RBD	NNP
cord-281793-tj4m01s4	78	26	for	for	IN
cord-281793-tj4m01s4	78	27	broad	broad	RB
cord-281793-tj4m01s4	78	28	-	-	HYPH
cord-281793-tj4m01s4	78	29	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	78	30	antibodies	antibody	NNS
cord-281793-tj4m01s4	78	31	against	against	IN
cord-281793-tj4m01s4	78	32	SARSr	SARSr	NNS
cord-281793-tj4m01s4	78	33	-	-	HYPH
cord-281793-tj4m01s4	78	34	CoVs	CoVs	NNP
cord-281793-tj4m01s4	78	35	.	.	.
cord-281793-tj4m01s4	79	1	In	in	IN
cord-281793-tj4m01s4	79	2	addition	addition	NN
cord-281793-tj4m01s4	79	3	to	to	IN
cord-281793-tj4m01s4	79	4	47D11	47d11	CD
cord-281793-tj4m01s4	79	5	,	,	,
cord-281793-tj4m01s4	79	6	another	another	DT
cord-281793-tj4m01s4	79	7	human	human	JJ
cord-281793-tj4m01s4	79	8	antibody	antibody	NN
cord-281793-tj4m01s4	79	9	(	(	-LRB-
cord-281793-tj4m01s4	79	10	S309	S309	NNS
cord-281793-tj4m01s4	79	11	)	)	-RRB-
cord-281793-tj4m01s4	79	12	isolated	isolate	VBN
cord-281793-tj4m01s4	79	13	from	from	IN
cord-281793-tj4m01s4	79	14	memory	memory	NN
cord-281793-tj4m01s4	79	15	B	b	NN
cord-281793-tj4m01s4	79	16	cells	cell	NNS
cord-281793-tj4m01s4	79	17	of	of	IN
cord-281793-tj4m01s4	79	18	a	a	DT
cord-281793-tj4m01s4	79	19	SARS	SARS	NNP
cord-281793-tj4m01s4	79	20	survivor	survivor	NN
cord-281793-tj4m01s4	79	21	infected	infect	VBN
cord-281793-tj4m01s4	79	22	in	in	IN
cord-281793-tj4m01s4	79	23	2003	2003	CD
cord-281793-tj4m01s4	79	24	neutralizes	neutralize	VBZ
cord-281793-tj4m01s4	79	25	SARS	SARS	NNP
cord-281793-tj4m01s4	79	26	-	-	HYPH
cord-281793-tj4m01s4	79	27	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	79	28	[	[	-LRB-
cord-281793-tj4m01s4	79	29	18	18	CD
cord-281793-tj4m01s4	79	30	]	]	-RRB-
cord-281793-tj4m01s4	79	31	.	.	.
cord-281793-tj4m01s4	80	1	Interestingly	interestingly	RB
cord-281793-tj4m01s4	80	2	,	,	,
cord-281793-tj4m01s4	80	3	S309	S309	NNP
cord-281793-tj4m01s4	80	4	recognizes	recognize	VBZ
cord-281793-tj4m01s4	80	5	a	a	DT
cord-281793-tj4m01s4	80	6	glycan	glycan	NN
cord-281793-tj4m01s4	80	7	-	-	HYPH
cord-281793-tj4m01s4	80	8	containing	contain	VBG
cord-281793-tj4m01s4	80	9	epitope	epitope	NN
cord-281793-tj4m01s4	80	10	on	on	IN
cord-281793-tj4m01s4	80	11	the	the	DT
cord-281793-tj4m01s4	80	12	RBD	RBD	NNP
cord-281793-tj4m01s4	80	13	in	in	IN
cord-281793-tj4m01s4	80	14	both	both	CC
cord-281793-tj4m01s4	80	15	the	the	DT
cord-281793-tj4m01s4	80	16	open	open	JJ
cord-281793-tj4m01s4	80	17	and	and	CC
cord-281793-tj4m01s4	80	18	closed	closed	JJ
cord-281793-tj4m01s4	80	19	S	S	NNP
cord-281793-tj4m01s4	80	20	states	state	NNS
cord-281793-tj4m01s4	80	21	.	.	.
cord-281793-tj4m01s4	81	1	The	the	DT
cord-281793-tj4m01s4	81	2	cryo	cryo	NN
cord-281793-tj4m01s4	81	3	-	-	HYPH
cord-281793-tj4m01s4	81	4	EM	EM	NNP
cord-281793-tj4m01s4	81	5	structure	structure	NN
cord-281793-tj4m01s4	81	6	of	of	IN
cord-281793-tj4m01s4	81	7	the	the	DT
cord-281793-tj4m01s4	81	8	complex	complex	NN
cord-281793-tj4m01s4	81	9	of	of	IN
cord-281793-tj4m01s4	81	10	S309	S309	NNP
cord-281793-tj4m01s4	81	11	and	and	CC
cord-281793-tj4m01s4	81	12	SARS	SARS	NNP
cord-281793-tj4m01s4	81	13	-	-	HYPH
cord-281793-tj4m01s4	81	14	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	81	15	S	S	NNP
cord-281793-tj4m01s4	81	16	protein	protein	NN
cord-281793-tj4m01s4	81	17	indicates	indicate	VBZ
cord-281793-tj4m01s4	81	18	that	that	IN
cord-281793-tj4m01s4	81	19	the	the	DT
cord-281793-tj4m01s4	81	20	antibody	antibody	NN
cord-281793-tj4m01s4	81	21	engages	engage	VBZ
cord-281793-tj4m01s4	81	22	an	an	DT
cord-281793-tj4m01s4	81	23	epitope	epitope	NN
cord-281793-tj4m01s4	81	24	distinct	distinct	JJ
cord-281793-tj4m01s4	81	25	from	from	IN
cord-281793-tj4m01s4	81	26	the	the	DT
cord-281793-tj4m01s4	81	27	ACE2	ACE2	NNP
cord-281793-tj4m01s4	81	28	binding	binding	NN
cord-281793-tj4m01s4	81	29	motif	motif	NN
cord-281793-tj4m01s4	81	30	and	and	CC
cord-281793-tj4m01s4	81	31	would	would	MD
cord-281793-tj4m01s4	81	32	not	not	RB
cord-281793-tj4m01s4	81	33	clash	clash	VB
cord-281793-tj4m01s4	81	34	with	with	IN
cord-281793-tj4m01s4	81	35	ACE2	ACE2	NNP
cord-281793-tj4m01s4	81	36	for	for	IN
cord-281793-tj4m01s4	81	37	its	-PRON-	PRP$
cord-281793-tj4m01s4	81	38	binding	binding	NN
cord-281793-tj4m01s4	81	39	to	to	IN
cord-281793-tj4m01s4	81	40	S	s	NN
cord-281793-tj4m01s4	81	41	protein	protein	NN
cord-281793-tj4m01s4	81	42	.	.	.
cord-281793-tj4m01s4	82	1	The	the	DT
cord-281793-tj4m01s4	82	2	glycan	glycan	NN
cord-281793-tj4m01s4	82	3	recognition	recognition	NN
cord-281793-tj4m01s4	82	4	of	of	IN
cord-281793-tj4m01s4	82	5	S309	S309	NNP
cord-281793-tj4m01s4	82	6	implies	imply	VBZ
cord-281793-tj4m01s4	82	7	the	the	DT
cord-281793-tj4m01s4	82	8	importance	importance	NN
cord-281793-tj4m01s4	82	9	of	of	IN
cord-281793-tj4m01s4	82	10	the	the	DT
cord-281793-tj4m01s4	82	11	N	N	NNP
cord-281793-tj4m01s4	82	12	-	-	HYPH
cord-281793-tj4m01s4	82	13	glycans	glycan	NNS
cord-281793-tj4m01s4	82	14	in	in	IN
cord-281793-tj4m01s4	82	15	SARS	SARS	NNP
cord-281793-tj4m01s4	82	16	-	-	HYPH
cord-281793-tj4m01s4	82	17	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	82	18	S	S	NNP
cord-281793-tj4m01s4	82	19	protein	protein	NN
cord-281793-tj4m01s4	82	20	.	.	.
cord-281793-tj4m01s4	83	1	Furthermore	furthermore	RB
cord-281793-tj4m01s4	83	2	,	,	,
cord-281793-tj4m01s4	83	3	antibody	antibody	NN
cord-281793-tj4m01s4	83	4	cocktails	cocktail	NNS
cord-281793-tj4m01s4	83	5	containing	contain	VBG
cord-281793-tj4m01s4	83	6	S309	S309	NNP
cord-281793-tj4m01s4	83	7	further	further	RB
cord-281793-tj4m01s4	83	8	improved	improve	VBN
cord-281793-tj4m01s4	83	9	SARS	SARS	NNP
cord-281793-tj4m01s4	83	10	-	-	HYPH
cord-281793-tj4m01s4	83	11	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	83	12	neutralization	neutralization	NN
cord-281793-tj4m01s4	83	13	and	and	CC
cord-281793-tj4m01s4	83	14	might	may	MD
cord-281793-tj4m01s4	83	15	be	be	VB
cord-281793-tj4m01s4	83	16	useful	useful	JJ
cord-281793-tj4m01s4	83	17	for	for	IN
cord-281793-tj4m01s4	83	18	preventing	prevent	VBG
cord-281793-tj4m01s4	83	19	or	or	CC
cord-281793-tj4m01s4	83	20	mitigating	mitigate	VBG
cord-281793-tj4m01s4	83	21	virus	virus	NN
cord-281793-tj4m01s4	83	22	escape	escape	NN
cord-281793-tj4m01s4	83	23	mutants	mutant	NNS
cord-281793-tj4m01s4	83	24	.	.	.
cord-281793-tj4m01s4	84	1	This	this	DT
cord-281793-tj4m01s4	84	2	supports	support	VBZ
cord-281793-tj4m01s4	84	3	the	the	DT
cord-281793-tj4m01s4	84	4	idea	idea	NN
cord-281793-tj4m01s4	84	5	that	that	IN
cord-281793-tj4m01s4	84	6	antibody	antibody	NN
cord-281793-tj4m01s4	84	7	cocktails	cocktail	NNS
cord-281793-tj4m01s4	84	8	could	could	MD
cord-281793-tj4m01s4	84	9	be	be	VB
cord-281793-tj4m01s4	84	10	more	more	RBR
cord-281793-tj4m01s4	84	11	effective	effective	JJ
cord-281793-tj4m01s4	84	12	than	than	IN
cord-281793-tj4m01s4	84	13	single	single	JJ
cord-281793-tj4m01s4	84	14	antibody	antibody	NN
cord-281793-tj4m01s4	84	15	therapy	therapy	NN
cord-281793-tj4m01s4	84	16	.	.	.
cord-281793-tj4m01s4	85	1	Besides	besides	IN
cord-281793-tj4m01s4	85	2	human	human	JJ
cord-281793-tj4m01s4	85	3	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	85	4	antibodies	antibody	NNS
cord-281793-tj4m01s4	85	5	,	,	,
cord-281793-tj4m01s4	85	6	a	a	DT
cord-281793-tj4m01s4	85	7	single	single	JJ
cord-281793-tj4m01s4	85	8	domain	domain	NN
cord-281793-tj4m01s4	85	9	camelid	camelid	NN
cord-281793-tj4m01s4	85	10	antibody	antibody	NN
cord-281793-tj4m01s4	85	11	(	(	-LRB-
cord-281793-tj4m01s4	85	12	VHH-72	VHH-72	NNP
cord-281793-tj4m01s4	85	13	)	)	-RRB-
cord-281793-tj4m01s4	85	14	,	,	,
cord-281793-tj4m01s4	85	15	commonly	commonly	RB
cord-281793-tj4m01s4	85	16	called	call	VBN
cord-281793-tj4m01s4	85	17	"	"	``
cord-281793-tj4m01s4	85	18	nanobody	nanobody	NNP
cord-281793-tj4m01s4	85	19	"	"	''
cord-281793-tj4m01s4	85	20	,	,	,
cord-281793-tj4m01s4	85	21	was	be	VBD
cord-281793-tj4m01s4	85	22	isolated	isolate	VBN
cord-281793-tj4m01s4	85	23	from	from	IN
cord-281793-tj4m01s4	85	24	a	a	DT
cord-281793-tj4m01s4	85	25	llama	llama	NN
cord-281793-tj4m01s4	85	26	immunized	immunize	VBN
cord-281793-tj4m01s4	85	27	with	with	IN
cord-281793-tj4m01s4	85	28	SARS	SARS	NNP
cord-281793-tj4m01s4	85	29	-	-	HYPH
cord-281793-tj4m01s4	85	30	CoV	CoV	NNP
cord-281793-tj4m01s4	85	31	S	S	NNP
cord-281793-tj4m01s4	85	32	and	and	CC
cord-281793-tj4m01s4	85	33	MERS	MERS	NNP
cord-281793-tj4m01s4	85	34	-	-	HYPH
cord-281793-tj4m01s4	85	35	CoV	CoV	NNP
cord-281793-tj4m01s4	85	36	S.	S.	NNP
cord-281793-tj4m01s4	86	1	This	this	DT
cord-281793-tj4m01s4	86	2	nanobody	nanobody	NN
cord-281793-tj4m01s4	86	3	showed	show	VBD
cord-281793-tj4m01s4	86	4	reactivity	reactivity	NN
cord-281793-tj4m01s4	86	5	with	with	IN
cord-281793-tj4m01s4	86	6	SARS	SARS	NNP
cord-281793-tj4m01s4	86	7	-	-	HYPH
cord-281793-tj4m01s4	86	8	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	86	9	S	S	NNP
cord-281793-tj4m01s4	86	10	protein	protein	NN
cord-281793-tj4m01s4	86	11	by	by	IN
cord-281793-tj4m01s4	86	12	binding	bind	VBG
cord-281793-tj4m01s4	86	13	to	to	IN
cord-281793-tj4m01s4	86	14	a	a	DT
cord-281793-tj4m01s4	86	15	highly	highly	RB
cord-281793-tj4m01s4	86	16	conserved	conserved	JJ
cord-281793-tj4m01s4	86	17	epitope	epitope	NN
cord-281793-tj4m01s4	86	18	on	on	IN
cord-281793-tj4m01s4	86	19	the	the	DT
cord-281793-tj4m01s4	86	20	RBD	RBD	NNP
cord-281793-tj4m01s4	86	21	partially	partially	RB
cord-281793-tj4m01s4	86	22	overlapping	overlap	VBG
cord-281793-tj4m01s4	86	23	the	the	DT
cord-281793-tj4m01s4	86	24	CR3022	cr3022	NN
cord-281793-tj4m01s4	86	25	binding	bind	VBG
cord-281793-tj4m01s4	86	26	site	site	NN
cord-281793-tj4m01s4	86	27	[	[	-LRB-
cord-281793-tj4m01s4	86	28	19	19	CD
cord-281793-tj4m01s4	86	29	]	]	-RRB-
cord-281793-tj4m01s4	86	30	.	.	.
cord-281793-tj4m01s4	87	1	However	however	RB
cord-281793-tj4m01s4	87	2	,	,	,
cord-281793-tj4m01s4	87	3	unlike	unlike	IN
cord-281793-tj4m01s4	87	4	CR3022	cr3022	NN
cord-281793-tj4m01s4	87	5	,	,	,
cord-281793-tj4m01s4	87	6	the	the	DT
cord-281793-tj4m01s4	87	7	bivalent	bivalent	JJ
cord-281793-tj4m01s4	87	8	VHH-72-Fc	VHH-72-Fc	NNP
cord-281793-tj4m01s4	87	9	fusion	fusion	NN
cord-281793-tj4m01s4	87	10	protein	protein	NN
cord-281793-tj4m01s4	87	11	not	not	RB
cord-281793-tj4m01s4	87	12	only	only	RB
cord-281793-tj4m01s4	87	13	prevents	prevent	VBZ
cord-281793-tj4m01s4	87	14	the	the	DT
cord-281793-tj4m01s4	87	15	binding	binding	NN
cord-281793-tj4m01s4	87	16	of	of	IN
cord-281793-tj4m01s4	87	17	ACE2	ACE2	NNP
cord-281793-tj4m01s4	87	18	but	but	CC
cord-281793-tj4m01s4	87	19	also	also	RB
cord-281793-tj4m01s4	87	20	has	have	VBZ
cord-281793-tj4m01s4	87	21	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	87	22	activity	activity	NN
cord-281793-tj4m01s4	87	23	against	against	IN
cord-281793-tj4m01s4	87	24	SARS	SARS	NNP
cord-281793-tj4m01s4	87	25	-	-	HYPH
cord-281793-tj4m01s4	87	26	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	87	27	pseudovirus	pseudovirus	NNP
cord-281793-tj4m01s4	87	28	.	.	.
cord-281793-tj4m01s4	88	1	The	the	DT
cord-281793-tj4m01s4	88	2	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	88	3	effects	effect	NNS
cord-281793-tj4m01s4	88	4	of	of	IN
cord-281793-tj4m01s4	88	5	47D11	47d11	CD
cord-281793-tj4m01s4	88	6	and	and	CC
cord-281793-tj4m01s4	88	7	VHH-72	vhh-72	RB
cord-281793-tj4m01s4	88	8	suggest	suggest	VB
cord-281793-tj4m01s4	88	9	that	that	IN
cord-281793-tj4m01s4	88	10	co	co	NN
cord-281793-tj4m01s4	88	11	-	-	JJ
cord-281793-tj4m01s4	88	12	immunizing	immunizing	JJ
cord-281793-tj4m01s4	88	13	animals	animal	NNS
cord-281793-tj4m01s4	88	14	with	with	IN
cord-281793-tj4m01s4	88	15	S	s	NN
cord-281793-tj4m01s4	88	16	proteins	protein	NNS
cord-281793-tj4m01s4	88	17	from	from	IN
cord-281793-tj4m01s4	88	18	SARS	SARS	NNP
cord-281793-tj4m01s4	88	19	-	-	HYPH
cord-281793-tj4m01s4	88	20	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	88	21	and	and	CC
cord-281793-tj4m01s4	88	22	other	other	JJ
cord-281793-tj4m01s4	88	23	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	88	24	may	may	MD
cord-281793-tj4m01s4	88	25	produce	produce	VB
cord-281793-tj4m01s4	88	26	potent	potent	JJ
cord-281793-tj4m01s4	88	27	broad	broad	RB
cord-281793-tj4m01s4	88	28	-	-	HYPH
cord-281793-tj4m01s4	88	29	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	88	30	antibodies	antibody	NNS
cord-281793-tj4m01s4	88	31	against	against	IN
cord-281793-tj4m01s4	88	32	SARS	SARS	NNP
cord-281793-tj4m01s4	88	33	-	-	HYPH
cord-281793-tj4m01s4	88	34	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	88	35	by	by	IN
cord-281793-tj4m01s4	88	36	targeting	target	VBG
cord-281793-tj4m01s4	88	37	the	the	DT
cord-281793-tj4m01s4	88	38	RBD	RBD	NNP
cord-281793-tj4m01s4	88	39	.	.	.
cord-281793-tj4m01s4	89	1	Single	single	JJ
cord-281793-tj4m01s4	89	2	domain	domain	NN
cord-281793-tj4m01s4	89	3	antibodies	antibody	NNS
cord-281793-tj4m01s4	89	4	have	have	VBP
cord-281793-tj4m01s4	89	5	unique	unique	JJ
cord-281793-tj4m01s4	89	6	binding	binding	NN
cord-281793-tj4m01s4	89	7	features	feature	NNS
cord-281793-tj4m01s4	89	8	[	[	-LRB-
cord-281793-tj4m01s4	89	9	20	20	CD
cord-281793-tj4m01s4	89	10	,	,	,
cord-281793-tj4m01s4	89	11	21	21	CD
cord-281793-tj4m01s4	89	12	]	]	-RRB-
cord-281793-tj4m01s4	89	13	,	,	,
cord-281793-tj4m01s4	89	14	so	so	IN
cord-281793-tj4m01s4	89	15	they	-PRON-	PRP
cord-281793-tj4m01s4	89	16	can	can	MD
cord-281793-tj4m01s4	89	17	bind	bind	VB
cord-281793-tj4m01s4	89	18	novel	novel	JJ
cord-281793-tj4m01s4	89	19	viral	viral	JJ
cord-281793-tj4m01s4	89	20	conformational	conformational	JJ
cord-281793-tj4m01s4	89	21	epitopes	epitope	NNS
cord-281793-tj4m01s4	89	22	including	include	VBG
cord-281793-tj4m01s4	89	23	highly	highly	RB
cord-281793-tj4m01s4	89	24	conformational	conformational	JJ
cord-281793-tj4m01s4	89	25	and/or	and/or	CC
cord-281793-tj4m01s4	89	26	buried	bury	VBN
cord-281793-tj4m01s4	89	27	sites	site	NNS
cord-281793-tj4m01s4	89	28	unreachable	unreachable	JJ
cord-281793-tj4m01s4	89	29	by	by	IN
cord-281793-tj4m01s4	89	30	conventional	conventional	JJ
cord-281793-tj4m01s4	89	31	antibodies	antibody	NNS
cord-281793-tj4m01s4	89	32	.	.	.
cord-281793-tj4m01s4	90	1	Besides	besides	IN
cord-281793-tj4m01s4	90	2	their	-PRON-	PRP$
cord-281793-tj4m01s4	90	3	unique	unique	JJ
cord-281793-tj4m01s4	90	4	binding	binding	NN
cord-281793-tj4m01s4	90	5	features	feature	NNS
cord-281793-tj4m01s4	90	6	,	,	,
cord-281793-tj4m01s4	90	7	other	other	JJ
cord-281793-tj4m01s4	90	8	advantages	advantage	NNS
cord-281793-tj4m01s4	90	9	include	include	VBP
cord-281793-tj4m01s4	90	10	the	the	DT
cord-281793-tj4m01s4	90	11	construction	construction	NN
cord-281793-tj4m01s4	90	12	of	of	IN
cord-281793-tj4m01s4	90	13	multivalent	multivalent	JJ
cord-281793-tj4m01s4	90	14	/	/	SYM
cord-281793-tj4m01s4	90	15	multispecific	multispecific	JJ
cord-281793-tj4m01s4	90	16	molecules	molecule	NNS
cord-281793-tj4m01s4	90	17	and	and	CC
cord-281793-tj4m01s4	90	18	thermostability	thermostability	NN
cord-281793-tj4m01s4	90	19	/	/	SYM
cord-281793-tj4m01s4	90	20	chemostability	chemostability	NN
cord-281793-tj4m01s4	90	21	[	[	-LRB-
cord-281793-tj4m01s4	90	22	22	22	CD
cord-281793-tj4m01s4	90	23	]	]	-RRB-
cord-281793-tj4m01s4	90	24	.	.	.
cord-281793-tj4m01s4	91	1	For	for	IN
cord-281793-tj4m01s4	91	2	respiratory	respiratory	JJ
cord-281793-tj4m01s4	91	3	infection	infection	NN
cord-281793-tj4m01s4	91	4	,	,	,
cord-281793-tj4m01s4	91	5	single	single	JJ
cord-281793-tj4m01s4	91	6	domain	domain	NN
cord-281793-tj4m01s4	91	7	antibodies	antibody	NNS
cord-281793-tj4m01s4	91	8	might	may	MD
cord-281793-tj4m01s4	91	9	be	be	VB
cord-281793-tj4m01s4	91	10	particularly	particularly	RB
cord-281793-tj4m01s4	91	11	attractive	attractive	JJ
cord-281793-tj4m01s4	91	12	because	because	IN
cord-281793-tj4m01s4	91	13	they	-PRON-	PRP
cord-281793-tj4m01s4	91	14	might	may	MD
cord-281793-tj4m01s4	91	15	be	be	VB
cord-281793-tj4m01s4	91	16	administered	administer	VBN
cord-281793-tj4m01s4	91	17	as	as	IN
cord-281793-tj4m01s4	91	18	an	an	DT
cord-281793-tj4m01s4	91	19	inhaler	inhaler	NN
cord-281793-tj4m01s4	91	20	directly	directly	RB
cord-281793-tj4m01s4	91	21	to	to	IN
cord-281793-tj4m01s4	91	22	the	the	DT
cord-281793-tj4m01s4	91	23	site	site	NN
cord-281793-tj4m01s4	91	24	of	of	IN
cord-281793-tj4m01s4	91	25	infection	infection	NN
cord-281793-tj4m01s4	91	26	[	[	-LRB-
cord-281793-tj4m01s4	91	27	19	19	CD
cord-281793-tj4m01s4	91	28	]	]	-RRB-
cord-281793-tj4m01s4	91	29	.	.	.
cord-281793-tj4m01s4	92	1	Both	both	DT
cord-281793-tj4m01s4	92	2	47D11	47d11	NN
cord-281793-tj4m01s4	92	3	and	and	CC
cord-281793-tj4m01s4	92	4	S309	S309	NNS
cord-281793-tj4m01s4	92	5	are	be	VBP
cord-281793-tj4m01s4	92	6	fully	fully	RB
cord-281793-tj4m01s4	92	7	human	human	JJ
cord-281793-tj4m01s4	92	8	IgG	igg	NN
cord-281793-tj4m01s4	92	9	molecules	molecule	NNS
cord-281793-tj4m01s4	92	10	,	,	,
cord-281793-tj4m01s4	92	11	whereas	whereas	IN
cord-281793-tj4m01s4	92	12	VHH-72	VHH-72	NNP
cord-281793-tj4m01s4	92	13	is	be	VBZ
cord-281793-tj4m01s4	92	14	a	a	DT
cord-281793-tj4m01s4	92	15	single	single	JJ
cord-281793-tj4m01s4	92	16	domain	domain	NN
cord-281793-tj4m01s4	92	17	antibody	antibody	NN
cord-281793-tj4m01s4	92	18	derived	derive	VBN
cord-281793-tj4m01s4	92	19	from	from	IN
cord-281793-tj4m01s4	92	20	a	a	DT
cord-281793-tj4m01s4	92	21	llama	llama	NN
cord-281793-tj4m01s4	92	22	heavy	heavy	JJ
cord-281793-tj4m01s4	92	23	chain	chain	NN
cord-281793-tj4m01s4	92	24	antibody	antibody	NN
cord-281793-tj4m01s4	92	25	that	that	WDT
cord-281793-tj4m01s4	92	26	has	have	VBZ
cord-281793-tj4m01s4	92	27	not	not	RB
cord-281793-tj4m01s4	92	28	been	be	VBN
cord-281793-tj4m01s4	92	29	humanized	humanize	VBN
cord-281793-tj4m01s4	92	30	yet	yet	RB
cord-281793-tj4m01s4	92	31	.	.	.
cord-281793-tj4m01s4	93	1	For	for	IN
cord-281793-tj4m01s4	93	2	therapeutic	therapeutic	JJ
cord-281793-tj4m01s4	93	3	applications	application	NNS
cord-281793-tj4m01s4	93	4	,	,	,
cord-281793-tj4m01s4	93	5	the	the	DT
cord-281793-tj4m01s4	93	6	camelid	camelid	NN
cord-281793-tj4m01s4	93	7	-	-	HYPH
cord-281793-tj4m01s4	93	8	specific	specific	JJ
cord-281793-tj4m01s4	93	9	sequences	sequence	NNS
cord-281793-tj4m01s4	93	10	in	in	IN
cord-281793-tj4m01s4	93	11	the	the	DT
cord-281793-tj4m01s4	93	12	framework	framework	NN
cord-281793-tj4m01s4	93	13	may	may	MD
cord-281793-tj4m01s4	93	14	need	need	VB
cord-281793-tj4m01s4	93	15	to	to	TO
cord-281793-tj4m01s4	93	16	be	be	VB
cord-281793-tj4m01s4	93	17	mutated	mutate	VBN
cord-281793-tj4m01s4	93	18	to	to	IN
cord-281793-tj4m01s4	93	19	their	-PRON-	PRP$
cord-281793-tj4m01s4	93	20	human	human	JJ
cord-281793-tj4m01s4	93	21	heavy	heavy	JJ
cord-281793-tj4m01s4	93	22	chain	chain	NN
cord-281793-tj4m01s4	93	23	variable	variable	NN
cord-281793-tj4m01s4	93	24	domain	domain	NN
cord-281793-tj4m01s4	93	25	equivalent	equivalent	NN
cord-281793-tj4m01s4	93	26	[	[	-LRB-
cord-281793-tj4m01s4	93	27	23	23	CD
cord-281793-tj4m01s4	93	28	]	]	-RRB-
cord-281793-tj4m01s4	93	29	.	.	.
cord-281793-tj4m01s4	94	1	Its	-PRON-	PRP$
cord-281793-tj4m01s4	94	2	suitability	suitability	NN
cord-281793-tj4m01s4	94	3	for	for	IN
cord-281793-tj4m01s4	94	4	prophylactic	prophylactic	JJ
cord-281793-tj4m01s4	94	5	and	and	CC
cord-281793-tj4m01s4	94	6	therapeutic	therapeutic	JJ
cord-281793-tj4m01s4	94	7	treatments	treatment	NNS
cord-281793-tj4m01s4	94	8	remains	remain	VBZ
cord-281793-tj4m01s4	94	9	to	to	TO
cord-281793-tj4m01s4	94	10	be	be	VB
cord-281793-tj4m01s4	94	11	determined	determine	VBN
cord-281793-tj4m01s4	94	12	.	.	.
cord-281793-tj4m01s4	95	1	It	-PRON-	PRP
cord-281793-tj4m01s4	95	2	might	may	MD
cord-281793-tj4m01s4	95	3	be	be	VB
cord-281793-tj4m01s4	95	4	useful	useful	JJ
cord-281793-tj4m01s4	95	5	to	to	TO
cord-281793-tj4m01s4	95	6	analyze	analyze	VB
cord-281793-tj4m01s4	95	7	the	the	DT
cord-281793-tj4m01s4	95	8	mutations	mutation	NNS
cord-281793-tj4m01s4	95	9	of	of	IN
cord-281793-tj4m01s4	95	10	SARS	SARS	NNP
cord-281793-tj4m01s4	95	11	-	-	HYPH
cord-281793-tj4m01s4	95	12	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	95	13	as	as	IN
cord-281793-tj4m01s4	95	14	it	-PRON-	PRP
cord-281793-tj4m01s4	95	15	spreads	spread	VBZ
cord-281793-tj4m01s4	95	16	worldwide	worldwide	RB
cord-281793-tj4m01s4	95	17	,	,	,
cord-281793-tj4m01s4	95	18	so	so	IN
cord-281793-tj4m01s4	95	19	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	95	20	antibodies	antibody	NNS
cord-281793-tj4m01s4	95	21	can	can	MD
cord-281793-tj4m01s4	95	22	be	be	VB
cord-281793-tj4m01s4	95	23	effective	effective	JJ
cord-281793-tj4m01s4	95	24	for	for	IN
cord-281793-tj4m01s4	95	25	multiple	multiple	JJ
cord-281793-tj4m01s4	95	26	strains	strain	NNS
cord-281793-tj4m01s4	95	27	of	of	IN
cord-281793-tj4m01s4	95	28	the	the	DT
cord-281793-tj4m01s4	95	29	virus	virus	NN
cord-281793-tj4m01s4	95	30	[	[	-LRB-
cord-281793-tj4m01s4	95	31	24	24	CD
cord-281793-tj4m01s4	95	32	]	]	-RRB-
cord-281793-tj4m01s4	95	33	[	[	-LRB-
cord-281793-tj4m01s4	95	34	25	25	CD
cord-281793-tj4m01s4	95	35	]	]	-RRB-
cord-281793-tj4m01s4	95	36	[	[	-LRB-
cord-281793-tj4m01s4	95	37	26	26	CD
cord-281793-tj4m01s4	95	38	]	]	-RRB-
cord-281793-tj4m01s4	95	39	.	.	.
cord-281793-tj4m01s4	96	1	Up	up	IN
cord-281793-tj4m01s4	96	2	to	to	IN
cord-281793-tj4m01s4	96	3	now	now	RB
cord-281793-tj4m01s4	96	4	,	,	,
cord-281793-tj4m01s4	96	5	most	most	JJS
cord-281793-tj4m01s4	96	6	of	of	IN
cord-281793-tj4m01s4	96	7	the	the	DT
cord-281793-tj4m01s4	96	8	mutations	mutation	NNS
cord-281793-tj4m01s4	96	9	found	find	VBN
cord-281793-tj4m01s4	96	10	in	in	IN
cord-281793-tj4m01s4	96	11	the	the	DT
cord-281793-tj4m01s4	96	12	RBD	RBD	NNP
cord-281793-tj4m01s4	96	13	of	of	IN
cord-281793-tj4m01s4	96	14	SARS	SARS	NNP
cord-281793-tj4m01s4	96	15	-	-	HYPH
cord-281793-tj4m01s4	96	16	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	96	17	are	be	VBP
cord-281793-tj4m01s4	96	18	of	of	IN
cord-281793-tj4m01s4	96	19	low	low	JJ
cord-281793-tj4m01s4	96	20	frequency	frequency	NN
cord-281793-tj4m01s4	96	21	[	[	-LRB-
cord-281793-tj4m01s4	96	22	26	26	CD
cord-281793-tj4m01s4	96	23	]	]	-RRB-
cord-281793-tj4m01s4	96	24	.	.	.
cord-281793-tj4m01s4	97	1	The	the	DT
cord-281793-tj4m01s4	97	2	G476S	G476S	NNP
cord-281793-tj4m01s4	97	3	mutation	mutation	NN
cord-281793-tj4m01s4	97	4	was	be	VBD
cord-281793-tj4m01s4	97	5	located	locate	VBN
cord-281793-tj4m01s4	97	6	in	in	IN
cord-281793-tj4m01s4	97	7	the	the	DT
cord-281793-tj4m01s4	97	8	binding	bind	VBG
cord-281793-tj4m01s4	97	9	interface	interface	NN
cord-281793-tj4m01s4	97	10	of	of	IN
cord-281793-tj4m01s4	97	11	the	the	DT
cord-281793-tj4m01s4	97	12	RBD	RBD	NNP
cord-281793-tj4m01s4	97	13	with	with	IN
cord-281793-tj4m01s4	97	14	the	the	DT
cord-281793-tj4m01s4	97	15	ACE2	ACE2	NNP
cord-281793-tj4m01s4	97	16	,	,	,
cord-281793-tj4m01s4	97	17	although	although	IN
cord-281793-tj4m01s4	97	18	it	-PRON-	PRP
cord-281793-tj4m01s4	97	19	occurred	occur	VBD
cord-281793-tj4m01s4	97	20	in	in	IN
cord-281793-tj4m01s4	97	21	early	early	JJ
cord-281793-tj4m01s4	97	22	samples	sample	NNS
cord-281793-tj4m01s4	97	23	and	and	CC
cord-281793-tj4m01s4	97	24	diminished	diminish	VBN
cord-281793-tj4m01s4	97	25	in	in	IN
cord-281793-tj4m01s4	97	26	late	late	JJ
cord-281793-tj4m01s4	97	27	samples	sample	NNS
cord-281793-tj4m01s4	97	28	,	,	,
cord-281793-tj4m01s4	97	29	indicating	indicate	VBG
cord-281793-tj4m01s4	97	30	that	that	IN
cord-281793-tj4m01s4	97	31	the	the	DT
cord-281793-tj4m01s4	97	32	virus	virus	NN
cord-281793-tj4m01s4	97	33	with	with	IN
cord-281793-tj4m01s4	97	34	mutations	mutation	NNS
cord-281793-tj4m01s4	97	35	in	in	IN
cord-281793-tj4m01s4	97	36	the	the	DT
cord-281793-tj4m01s4	97	37	critical	critical	JJ
cord-281793-tj4m01s4	97	38	functional	functional	JJ
cord-281793-tj4m01s4	97	39	site	site	NN
cord-281793-tj4m01s4	97	40	might	may	MD
cord-281793-tj4m01s4	97	41	not	not	RB
cord-281793-tj4m01s4	97	42	have	have	VB
cord-281793-tj4m01s4	97	43	advantage	advantage	NN
cord-281793-tj4m01s4	97	44	for	for	IN
cord-281793-tj4m01s4	97	45	its	-PRON-	PRP$
cord-281793-tj4m01s4	97	46	survival	survival	NN
cord-281793-tj4m01s4	97	47	or	or	CC
cord-281793-tj4m01s4	97	48	spread	spread	NN
cord-281793-tj4m01s4	97	49	.	.	.
cord-281793-tj4m01s4	98	1	While	while	IN
cord-281793-tj4m01s4	98	2	the	the	DT
cord-281793-tj4m01s4	98	3	RBD	RBD	NNP
cord-281793-tj4m01s4	98	4	is	be	VBZ
cord-281793-tj4m01s4	98	5	the	the	DT
cord-281793-tj4m01s4	98	6	focus	focus	NN
cord-281793-tj4m01s4	98	7	for	for	IN
cord-281793-tj4m01s4	98	8	the	the	DT
cord-281793-tj4m01s4	98	9	development	development	NN
cord-281793-tj4m01s4	98	10	of	of	IN
cord-281793-tj4m01s4	98	11	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	98	12	antibodies	antibody	NNS
cord-281793-tj4m01s4	98	13	against	against	IN
cord-281793-tj4m01s4	98	14	SARS	SARS	NNP
cord-281793-tj4m01s4	98	15	-	-	HYPH
cord-281793-tj4m01s4	98	16	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	98	17	,	,	,
cord-281793-tj4m01s4	98	18	the	the	DT
cord-281793-tj4m01s4	98	19	function	function	NN
cord-281793-tj4m01s4	98	20	of	of	IN
cord-281793-tj4m01s4	98	21	non	non	JJ
cord-281793-tj4m01s4	98	22	-	-	JJ
cord-281793-tj4m01s4	98	23	RBD	rbd	JJ
cord-281793-tj4m01s4	98	24	regions	region	NNS
cord-281793-tj4m01s4	98	25	is	be	VBZ
cord-281793-tj4m01s4	98	26	poorly	poorly	RB
cord-281793-tj4m01s4	98	27	understood	understand	VBN
cord-281793-tj4m01s4	98	28	.	.	.
cord-281793-tj4m01s4	99	1	Recently	recently	RB
cord-281793-tj4m01s4	99	2	,	,	,
cord-281793-tj4m01s4	99	3	an	an	DT
cord-281793-tj4m01s4	99	4	antibody	antibody	NN
cord-281793-tj4m01s4	99	5	(	(	-LRB-
cord-281793-tj4m01s4	99	6	4A8	4a8	CD
cord-281793-tj4m01s4	99	7	)	)	-RRB-
cord-281793-tj4m01s4	99	8	isolated	isolate	VBN
cord-281793-tj4m01s4	99	9	from	from	IN
cord-281793-tj4m01s4	99	10	convalescent	convalescent	JJ
cord-281793-tj4m01s4	100	1	COVID-19	covid-19	JJ
cord-281793-tj4m01s4	100	2	patients	patient	NNS
cord-281793-tj4m01s4	100	3	shows	show	VBZ
cord-281793-tj4m01s4	100	4	the	the	DT
cord-281793-tj4m01s4	100	5	binding	binding	NN
cord-281793-tj4m01s4	100	6	on	on	IN
cord-281793-tj4m01s4	100	7	the	the	DT
cord-281793-tj4m01s4	100	8	N	n	CD
cord-281793-tj4m01s4	100	9	-	-	HYPH
cord-281793-tj4m01s4	100	10	terminal	terminal	NN
cord-281793-tj4m01s4	100	11	domain	domain	NN
cord-281793-tj4m01s4	100	12	(	(	-LRB-
cord-281793-tj4m01s4	100	13	NTD	NTD	NNP
cord-281793-tj4m01s4	100	14	)	)	-RRB-
cord-281793-tj4m01s4	100	15	of	of	IN
cord-281793-tj4m01s4	100	16	the	the	DT
cord-281793-tj4m01s4	100	17	SARS	SARS	NNP
cord-281793-tj4m01s4	100	18	-	-	HYPH
cord-281793-tj4m01s4	100	19	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	100	20	S	S	NNP
cord-281793-tj4m01s4	100	21	protein	protein	NN
cord-281793-tj4m01s4	100	22	and	and	CC
cord-281793-tj4m01s4	100	23	exhibits	exhibit	VBZ
cord-281793-tj4m01s4	100	24	high	high	JJ
cord-281793-tj4m01s4	100	25	neutralization	neutralization	NN
cord-281793-tj4m01s4	100	26	potency	potency	NN
cord-281793-tj4m01s4	100	27	SARS	SARS	NNP
cord-281793-tj4m01s4	100	28	-	-	HYPH
cord-281793-tj4m01s4	100	29	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	100	30	.	.	.
cord-281793-tj4m01s4	101	1	The	the	DT
cord-281793-tj4m01s4	101	2	structural	structural	JJ
cord-281793-tj4m01s4	101	3	analysis	analysis	NN
cord-281793-tj4m01s4	101	4	has	have	VBZ
cord-281793-tj4m01s4	101	5	confirmed	confirm	VBN
cord-281793-tj4m01s4	101	6	its	-PRON-	PRP$
cord-281793-tj4m01s4	101	7	binding	binding	NN
cord-281793-tj4m01s4	101	8	to	to	IN
cord-281793-tj4m01s4	101	9	the	the	DT
cord-281793-tj4m01s4	101	10	NTD	NTD	NNP
cord-281793-tj4m01s4	101	11	,	,	,
cord-281793-tj4m01s4	101	12	not	not	RB
cord-281793-tj4m01s4	101	13	the	the	DT
cord-281793-tj4m01s4	101	14	RBD	RBD	NNP
cord-281793-tj4m01s4	101	15	which	which	WDT
cord-281793-tj4m01s4	101	16	directly	directly	RB
cord-281793-tj4m01s4	101	17	interacts	interact	VBZ
cord-281793-tj4m01s4	101	18	with	with	IN
cord-281793-tj4m01s4	101	19	ACE2	ACE2	NNP
cord-281793-tj4m01s4	101	20	,	,	,
cord-281793-tj4m01s4	101	21	demonstrating	demonstrate	VBG
cord-281793-tj4m01s4	101	22	a	a	DT
cord-281793-tj4m01s4	101	23	new	new	JJ
cord-281793-tj4m01s4	101	24	vulnerable	vulnerable	JJ
cord-281793-tj4m01s4	101	25	epitope	epitope	NN
cord-281793-tj4m01s4	101	26	in	in	IN
cord-281793-tj4m01s4	101	27	the	the	DT
cord-281793-tj4m01s4	101	28	S1	s1	NN
cord-281793-tj4m01s4	101	29	subunit	subunit	NN
cord-281793-tj4m01s4	101	30	as	as	IN
cord-281793-tj4m01s4	101	31	a	a	DT
cord-281793-tj4m01s4	101	32	target	target	NN
cord-281793-tj4m01s4	101	33	of	of	IN
cord-281793-tj4m01s4	101	34	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	101	35	antibodies	antibody	NNS
cord-281793-tj4m01s4	101	36	for	for	IN
cord-281793-tj4m01s4	101	37	treating	treat	VBG
cord-281793-tj4m01s4	101	38	COVID-19	covid-19	ADD
cord-281793-tj4m01s4	101	39	[	[	-LRB-
cord-281793-tj4m01s4	101	40	27	27	CD
cord-281793-tj4m01s4	101	41	]	]	-RRB-
cord-281793-tj4m01s4	101	42	.	.	.
cord-281793-tj4m01s4	102	1	Antibodies	antibody	NNS
cord-281793-tj4m01s4	102	2	that	that	WDT
cord-281793-tj4m01s4	102	3	target	target	VBP
cord-281793-tj4m01s4	102	4	the	the	DT
cord-281793-tj4m01s4	102	5	S	S	NNP
cord-281793-tj4m01s4	102	6	protein	protein	NN
cord-281793-tj4m01s4	102	7	beyond	beyond	IN
cord-281793-tj4m01s4	102	8	the	the	DT
cord-281793-tj4m01s4	102	9	S1	s1	NN
cord-281793-tj4m01s4	102	10	subunit	subunit	NN
cord-281793-tj4m01s4	102	11	have	have	VBP
cord-281793-tj4m01s4	102	12	rarely	rarely	RB
cord-281793-tj4m01s4	102	13	been	be	VBN
cord-281793-tj4m01s4	102	14	reported	report	VBN
cord-281793-tj4m01s4	102	15	.	.	.
cord-281793-tj4m01s4	103	1	The	the	DT
cord-281793-tj4m01s4	103	2	S2	s2	NN
cord-281793-tj4m01s4	103	3	subunit	subunit	NN
cord-281793-tj4m01s4	103	4	,	,	,
cord-281793-tj4m01s4	103	5	in	in	IN
cord-281793-tj4m01s4	103	6	particular	particular	JJ
cord-281793-tj4m01s4	103	7	heptad	heptad	NN
cord-281793-tj4m01s4	103	8	repeat	repeat	NN
cord-281793-tj4m01s4	103	9	(	(	-LRB-
cord-281793-tj4m01s4	103	10	HR	hr	NN
cord-281793-tj4m01s4	103	11	)	)	-RRB-
cord-281793-tj4m01s4	103	12	loops	loop	NNS
cord-281793-tj4m01s4	103	13	including	include	VBG
cord-281793-tj4m01s4	103	14	HR1	HR1	NNP
cord-281793-tj4m01s4	103	15	and	and	CC
cord-281793-tj4m01s4	103	16	HR2	HR2	NNP
cord-281793-tj4m01s4	103	17	domains	domain	NNS
cord-281793-tj4m01s4	103	18	,	,	,
cord-281793-tj4m01s4	103	19	required	require	VBN
cord-281793-tj4m01s4	103	20	for	for	IN
cord-281793-tj4m01s4	103	21	membrane	membrane	NN
cord-281793-tj4m01s4	103	22	fusion	fusion	NN
cord-281793-tj4m01s4	103	23	might	may	MD
cord-281793-tj4m01s4	103	24	be	be	VB
cord-281793-tj4m01s4	103	25	another	another	DT
cord-281793-tj4m01s4	103	26	target	target	NN
cord-281793-tj4m01s4	103	27	.	.	.
cord-281793-tj4m01s4	104	1	The	the	DT
cord-281793-tj4m01s4	104	2	1A9	1a9	CD
cord-281793-tj4m01s4	104	3	antibody	antibody	NN
cord-281793-tj4m01s4	104	4	is	be	VBZ
cord-281793-tj4m01s4	104	5	the	the	DT
cord-281793-tj4m01s4	104	6	only	only	RB
cord-281793-tj4m01s4	104	7	known	know	VBN
cord-281793-tj4m01s4	104	8	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	104	9	antibody	antibody	NN
cord-281793-tj4m01s4	104	10	that	that	WDT
cord-281793-tj4m01s4	104	11	binds	bind	VBZ
cord-281793-tj4m01s4	104	12	the	the	DT
cord-281793-tj4m01s4	104	13	HR2	HR2	NNP
cord-281793-tj4m01s4	104	14	domain	domain	NN
cord-281793-tj4m01s4	104	15	on	on	IN
cord-281793-tj4m01s4	104	16	S2	S2	NNP
cord-281793-tj4m01s4	104	17	subunit	subunit	NN
cord-281793-tj4m01s4	104	18	of	of	IN
cord-281793-tj4m01s4	104	19	SARS	SARS	NNP
cord-281793-tj4m01s4	104	20	-	-	HYPH
cord-281793-tj4m01s4	104	21	CoV	CoV	NNP
cord-281793-tj4m01s4	104	22	[	[	-LRB-
cord-281793-tj4m01s4	104	23	28	28	CD
cord-281793-tj4m01s4	104	24	]	]	-RRB-
cord-281793-tj4m01s4	105	1	(	(	-LRB-
cord-281793-tj4m01s4	105	2	Fig	Fig	NNP
cord-281793-tj4m01s4	105	3	.	.	NNP
cord-281793-tj4m01s4	105	4	1	1	CD
cord-281793-tj4m01s4	105	5	)	)	-RRB-
cord-281793-tj4m01s4	105	6	.	.	.
cord-281793-tj4m01s4	106	1	A	a	DT
cord-281793-tj4m01s4	106	2	more	more	RBR
cord-281793-tj4m01s4	106	3	recent	recent	JJ
cord-281793-tj4m01s4	106	4	study	study	NN
cord-281793-tj4m01s4	106	5	showed	show	VBD
cord-281793-tj4m01s4	106	6	that	that	IN
cord-281793-tj4m01s4	106	7	SARS	SARS	NNP
cord-281793-tj4m01s4	106	8	-	-	HYPH
cord-281793-tj4m01s4	106	9	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	106	10	had	have	VBD
cord-281793-tj4m01s4	106	11	a	a	DT
cord-281793-tj4m01s4	106	12	superior	superior	JJ
cord-281793-tj4m01s4	106	13	plasma	plasma	NN
cord-281793-tj4m01s4	106	14	membrane	membrane	NN
cord-281793-tj4m01s4	106	15	fusion	fusion	NN
cord-281793-tj4m01s4	106	16	capacity	capacity	NN
cord-281793-tj4m01s4	106	17	compared	compare	VBN
cord-281793-tj4m01s4	106	18	with	with	IN
cord-281793-tj4m01s4	106	19	that	that	DT
cord-281793-tj4m01s4	106	20	of	of	IN
cord-281793-tj4m01s4	106	21	SARS	SARS	NNP
cord-281793-tj4m01s4	106	22	-	-	HYPH
cord-281793-tj4m01s4	106	23	CoV	CoV	NNP
cord-281793-tj4m01s4	106	24	[	[	-LRB-
cord-281793-tj4m01s4	106	25	29	29	CD
cord-281793-tj4m01s4	106	26	]	]	-RRB-
cord-281793-tj4m01s4	106	27	.	.	.
cord-281793-tj4m01s4	107	1	The	the	DT
cord-281793-tj4m01s4	107	2	X	x	NN
cord-281793-tj4m01s4	107	3	-	-	NN
cord-281793-tj4m01s4	107	4	ray	ray	NN
cord-281793-tj4m01s4	107	5	crystal	crystal	NN
cord-281793-tj4m01s4	107	6	structure	structure	NN
cord-281793-tj4m01s4	107	7	of	of	IN
cord-281793-tj4m01s4	107	8	six	six	CD
cord-281793-tj4m01s4	107	9	-	-	HYPH
cord-281793-tj4m01s4	107	10	helical	helical	JJ
cord-281793-tj4m01s4	107	11	bundle	bundle	NN
cord-281793-tj4m01s4	107	12	(	(	-LRB-
cord-281793-tj4m01s4	107	13	6-HB	6-hb	CD
cord-281793-tj4m01s4	107	14	)	)	-RRB-
cord-281793-tj4m01s4	107	15	core	core	NN
cord-281793-tj4m01s4	107	16	of	of	IN
cord-281793-tj4m01s4	107	17	the	the	DT
cord-281793-tj4m01s4	107	18	HR1	HR1	NNP
cord-281793-tj4m01s4	107	19	and	and	CC
cord-281793-tj4m01s4	107	20	HR2	HR2	NNP
cord-281793-tj4m01s4	107	21	domains	domain	NNS
cord-281793-tj4m01s4	107	22	in	in	IN
cord-281793-tj4m01s4	107	23	the	the	DT
cord-281793-tj4m01s4	107	24	SARS	SARS	NNP
cord-281793-tj4m01s4	107	25	-	-	HYPH
cord-281793-tj4m01s4	107	26	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	107	27	S	S	NNP
cord-281793-tj4m01s4	107	28	protein	protein	NN
cord-281793-tj4m01s4	107	29	S2	s2	NN
cord-281793-tj4m01s4	107	30	subunit	subunit	NN
cord-281793-tj4m01s4	107	31	has	have	VBZ
cord-281793-tj4m01s4	107	32	also	also	RB
cord-281793-tj4m01s4	107	33	been	be	VBN
cord-281793-tj4m01s4	107	34	solved	solve	VBN
cord-281793-tj4m01s4	107	35	[	[	-LRB-
cord-281793-tj4m01s4	107	36	29	29	CD
cord-281793-tj4m01s4	107	37	]	]	-RRB-
cord-281793-tj4m01s4	107	38	.	.	.
cord-281793-tj4m01s4	108	1	A	a	DT
cord-281793-tj4m01s4	108	2	lipopeptide	lipopeptide	NN
cord-281793-tj4m01s4	108	3	(	(	-LRB-
cord-281793-tj4m01s4	108	4	EK1C4	ek1c4	RB
cord-281793-tj4m01s4	108	5	)	)	-RRB-
cord-281793-tj4m01s4	108	6	that	that	WDT
cord-281793-tj4m01s4	108	7	disturbs	disturb	VBZ
cord-281793-tj4m01s4	108	8	viral	viral	JJ
cord-281793-tj4m01s4	108	9	6-HB	6-hb	CD
cord-281793-tj4m01s4	108	10	formation	formation	NN
cord-281793-tj4m01s4	108	11	by	by	IN
cord-281793-tj4m01s4	108	12	binding	bind	VBG
cord-281793-tj4m01s4	108	13	the	the	DT
cord-281793-tj4m01s4	108	14	HR1	HR1	NNP
cord-281793-tj4m01s4	108	15	domain	domain	NN
cord-281793-tj4m01s4	108	16	can	can	MD
cord-281793-tj4m01s4	108	17	inhibit	inhibit	VB
cord-281793-tj4m01s4	108	18	the	the	DT
cord-281793-tj4m01s4	108	19	fusion	fusion	NN
cord-281793-tj4m01s4	108	20	of	of	IN
cord-281793-tj4m01s4	108	21	SARS	SARS	NNP
cord-281793-tj4m01s4	108	22	-	-	HYPH
cord-281793-tj4m01s4	108	23	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	108	24	as	as	RB
cord-281793-tj4m01s4	108	25	well	well	RB
cord-281793-tj4m01s4	108	26	as	as	IN
cord-281793-tj4m01s4	108	27	other	other	JJ
cord-281793-tj4m01s4	108	28	human	human	JJ
cord-281793-tj4m01s4	108	29	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	108	30	including	include	VBG
cord-281793-tj4m01s4	108	31	SARS	SARS	NNP
cord-281793-tj4m01s4	108	32	-	-	HYPH
cord-281793-tj4m01s4	108	33	CoV	CoV	NNP
cord-281793-tj4m01s4	108	34	and	and	CC
cord-281793-tj4m01s4	108	35	MERS	MERS	NNP
cord-281793-tj4m01s4	108	36	-	-	HYPH
cord-281793-tj4m01s4	108	37	CoV	CoV	NNP
cord-281793-tj4m01s4	108	38	,	,	,
cord-281793-tj4m01s4	108	39	suggesting	suggest	VBG
cord-281793-tj4m01s4	108	40	that	that	IN
cord-281793-tj4m01s4	108	41	a	a	DT
cord-281793-tj4m01s4	108	42	broad	broad	JJ
cord-281793-tj4m01s4	108	43	inhibitor	inhibitor	NN
cord-281793-tj4m01s4	108	44	targeting	target	VBG
cord-281793-tj4m01s4	108	45	the	the	DT
cord-281793-tj4m01s4	108	46	HR	hr	NN
cord-281793-tj4m01s4	108	47	region	region	NN
cord-281793-tj4m01s4	108	48	should	should	MD
cord-281793-tj4m01s4	108	49	be	be	VB
cord-281793-tj4m01s4	108	50	tested	test	VBN
cord-281793-tj4m01s4	108	51	for	for	IN
cord-281793-tj4m01s4	108	52	the	the	DT
cord-281793-tj4m01s4	108	53	treatment	treatment	NN
cord-281793-tj4m01s4	108	54	of	of	IN
cord-281793-tj4m01s4	108	55	infection	infection	NN
cord-281793-tj4m01s4	108	56	by	by	IN
cord-281793-tj4m01s4	108	57	current	current	JJ
cord-281793-tj4m01s4	108	58	and	and	CC
cord-281793-tj4m01s4	108	59	future	future	JJ
cord-281793-tj4m01s4	108	60	SARSr	SARSr	NNS
cord-281793-tj4m01s4	108	61	-	-	HYPH
cord-281793-tj4m01s4	108	62	CoVs	CoVs	NNP
cord-281793-tj4m01s4	108	63	.	.	.
cord-281793-tj4m01s4	109	1	Besides	besides	IN
cord-281793-tj4m01s4	109	2	widely	widely	RB
cord-281793-tj4m01s4	109	3	studied	study	VBN
cord-281793-tj4m01s4	109	4	protein	protein	NN
cord-281793-tj4m01s4	109	5	targets	target	NNS
cord-281793-tj4m01s4	109	6	,	,	,
cord-281793-tj4m01s4	109	7	glycan	glycan	NN
cord-281793-tj4m01s4	109	8	targets	target	NNS
cord-281793-tj4m01s4	109	9	might	may	MD
cord-281793-tj4m01s4	109	10	be	be	VB
cord-281793-tj4m01s4	109	11	worth	worth	JJ
cord-281793-tj4m01s4	109	12	exploring	explore	VBG
cord-281793-tj4m01s4	109	13	as	as	RB
cord-281793-tj4m01s4	109	14	well	well	RB
cord-281793-tj4m01s4	109	15	.	.	.
cord-281793-tj4m01s4	110	1	The	the	DT
cord-281793-tj4m01s4	110	2	S	S	NNP
cord-281793-tj4m01s4	110	3	protein	protein	NN
cord-281793-tj4m01s4	110	4	of	of	IN
cord-281793-tj4m01s4	110	5	SARS	SARS	NNP
cord-281793-tj4m01s4	110	6	-	-	HYPH
cord-281793-tj4m01s4	110	7	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	110	8	is	be	VBZ
cord-281793-tj4m01s4	110	9	highly	highly	RB
cord-281793-tj4m01s4	110	10	glycosylated	glycosylate	VBN
cord-281793-tj4m01s4	110	11	[	[	-LRB-
cord-281793-tj4m01s4	110	12	11	11	CD
cord-281793-tj4m01s4	110	13	]	]	-RRB-
cord-281793-tj4m01s4	110	14	.	.	.
cord-281793-tj4m01s4	111	1	Isolation	isolation	NN
cord-281793-tj4m01s4	111	2	of	of	IN
cord-281793-tj4m01s4	111	3	the	the	DT
cord-281793-tj4m01s4	111	4	S309	S309	NNS
cord-281793-tj4m01s4	111	5	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	111	6	antibody	antibody	NN
cord-281793-tj4m01s4	111	7	that	that	WDT
cord-281793-tj4m01s4	111	8	recognizes	recognize	VBZ
cord-281793-tj4m01s4	111	9	a	a	DT
cord-281793-tj4m01s4	111	10	glycan	glycan	NN
cord-281793-tj4m01s4	111	11	-	-	HYPH
cord-281793-tj4m01s4	111	12	containing	contain	VBG
cord-281793-tj4m01s4	111	13	epitope	epitope	NN
cord-281793-tj4m01s4	111	14	on	on	IN
cord-281793-tj4m01s4	111	15	the	the	DT
cord-281793-tj4m01s4	111	16	RBD	RBD	NNP
cord-281793-tj4m01s4	111	17	indicates	indicate	VBZ
cord-281793-tj4m01s4	111	18	that	that	IN
cord-281793-tj4m01s4	111	19	glycosylation	glycosylation	NN
cord-281793-tj4m01s4	111	20	on	on	IN
cord-281793-tj4m01s4	111	21	the	the	DT
cord-281793-tj4m01s4	111	22	S	S	NNP
cord-281793-tj4m01s4	111	23	protein	protein	NN
cord-281793-tj4m01s4	111	24	would	would	MD
cord-281793-tj4m01s4	111	25	affect	affect	VB
cord-281793-tj4m01s4	111	26	the	the	DT
cord-281793-tj4m01s4	111	27	development	development	NN
cord-281793-tj4m01s4	111	28	of	of	IN
cord-281793-tj4m01s4	111	29	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	111	30	antibodies	antibody	NNS
cord-281793-tj4m01s4	111	31	targeting	target	VBG
cord-281793-tj4m01s4	111	32	SARS	SARS	NNP
cord-281793-tj4m01s4	111	33	-	-	HYPH
cord-281793-tj4m01s4	111	34	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	111	35	[	[	-LRB-
cord-281793-tj4m01s4	111	36	18	18	CD
cord-281793-tj4m01s4	111	37	]	]	-RRB-
cord-281793-tj4m01s4	111	38	.	.	.
cord-281793-tj4m01s4	112	1	On	on	IN
cord-281793-tj4m01s4	112	2	the	the	DT
cord-281793-tj4m01s4	112	3	host	host	NN
cord-281793-tj4m01s4	112	4	cell	cell	NN
cord-281793-tj4m01s4	112	5	,	,	,
cord-281793-tj4m01s4	112	6	the	the	DT
cord-281793-tj4m01s4	112	7	primary	primary	JJ
cord-281793-tj4m01s4	112	8	target	target	NN
cord-281793-tj4m01s4	112	9	is	be	VBZ
cord-281793-tj4m01s4	112	10	the	the	DT
cord-281793-tj4m01s4	112	11	viral	viral	JJ
cord-281793-tj4m01s4	112	12	entry	entry	NN
cord-281793-tj4m01s4	112	13	protein	protein	NN
cord-281793-tj4m01s4	112	14	,	,	,
cord-281793-tj4m01s4	112	15	ACE2	ACE2	NNP
cord-281793-tj4m01s4	112	16	.	.	.
cord-281793-tj4m01s4	113	1	It	-PRON-	PRP
cord-281793-tj4m01s4	113	2	has	have	VBZ
cord-281793-tj4m01s4	113	3	been	be	VBN
cord-281793-tj4m01s4	113	4	proposed	propose	VBN
cord-281793-tj4m01s4	113	5	that	that	IN
cord-281793-tj4m01s4	113	6	recombinant	recombinant	JJ
cord-281793-tj4m01s4	113	7	ACE2	ACE2	NNP
cord-281793-tj4m01s4	113	8	might	may	MD
cord-281793-tj4m01s4	113	9	be	be	VB
cord-281793-tj4m01s4	113	10	used	use	VBN
cord-281793-tj4m01s4	113	11	as	as	IN
cord-281793-tj4m01s4	113	12	a	a	DT
cord-281793-tj4m01s4	113	13	potential	potential	JJ
cord-281793-tj4m01s4	113	14	inhibitor	inhibitor	NN
cord-281793-tj4m01s4	113	15	to	to	TO
cord-281793-tj4m01s4	113	16	block	block	VB
cord-281793-tj4m01s4	113	17	the	the	DT
cord-281793-tj4m01s4	113	18	virus	virus	NN
cord-281793-tj4m01s4	113	19	entry	entry	NN
cord-281793-tj4m01s4	113	20	[	[	-LRB-
cord-281793-tj4m01s4	113	21	30	30	CD
cord-281793-tj4m01s4	113	22	]	]	-RRB-
cord-281793-tj4m01s4	113	23	.	.	.
cord-281793-tj4m01s4	114	1	The	the	DT
cord-281793-tj4m01s4	114	2	ACE2-human	ACE2-human	NNP
cord-281793-tj4m01s4	114	3	IgG1	igg1	NN
cord-281793-tj4m01s4	114	4	Fc	Fc	NNP
cord-281793-tj4m01s4	114	5	fusion	fusion	NN
cord-281793-tj4m01s4	114	6	has	have	VBZ
cord-281793-tj4m01s4	114	7	been	be	VBN
cord-281793-tj4m01s4	114	8	engineered	engineer	VBN
cord-281793-tj4m01s4	114	9	.	.	.
cord-281793-tj4m01s4	115	1	The	the	DT
cord-281793-tj4m01s4	115	2	fusion	fusion	NN
cord-281793-tj4m01s4	115	3	protein	protein	NN
cord-281793-tj4m01s4	115	4	can	can	MD
cord-281793-tj4m01s4	115	5	neutralize	neutralize	VB
cord-281793-tj4m01s4	115	6	pseudoviruses	pseudoviruse	NNS
cord-281793-tj4m01s4	115	7	that	that	WDT
cord-281793-tj4m01s4	115	8	express	express	VBP
cord-281793-tj4m01s4	115	9	the	the	DT
cord-281793-tj4m01s4	115	10	S	S	NNP
cord-281793-tj4m01s4	115	11	proteins	protein	NNS
cord-281793-tj4m01s4	115	12	of	of	IN
cord-281793-tj4m01s4	115	13	SARS	SARS	NNP
cord-281793-tj4m01s4	115	14	-	-	HYPH
cord-281793-tj4m01s4	115	15	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	115	16	or	or	CC
cord-281793-tj4m01s4	115	17	SARS	SARS	NNP
cord-281793-tj4m01s4	115	18	-	-	HYPH
cord-281793-tj4m01s4	115	19	CoV	CoV	NNP
cord-281793-tj4m01s4	115	20	in	in	IN
cord-281793-tj4m01s4	115	21	cell	cell	NN
cord-281793-tj4m01s4	115	22	culture	culture	NN
cord-281793-tj4m01s4	115	23	[	[	-LRB-
cord-281793-tj4m01s4	115	24	31	31	CD
cord-281793-tj4m01s4	115	25	]	]	-RRB-
cord-281793-tj4m01s4	115	26	.	.	.
cord-281793-tj4m01s4	116	1	Heparan	heparan	JJ
cord-281793-tj4m01s4	116	2	sulfate	sulfate	NN
cord-281793-tj4m01s4	116	3	proteoglycans	proteoglycan	NNS
cord-281793-tj4m01s4	116	4	(	(	-LRB-
cord-281793-tj4m01s4	116	5	HSPGs	hspg	NNS
cord-281793-tj4m01s4	116	6	)	)	-RRB-
cord-281793-tj4m01s4	116	7	provide	provide	VB
cord-281793-tj4m01s4	116	8	the	the	DT
cord-281793-tj4m01s4	116	9	initial	initial	JJ
cord-281793-tj4m01s4	116	10	sites	site	NNS
cord-281793-tj4m01s4	116	11	for	for	IN
cord-281793-tj4m01s4	116	12	the	the	DT
cord-281793-tj4m01s4	116	13	virus	virus	NN
cord-281793-tj4m01s4	116	14	to	to	TO
cord-281793-tj4m01s4	116	15	make	make	VB
cord-281793-tj4m01s4	116	16	primary	primary	JJ
cord-281793-tj4m01s4	116	17	contact	contact	NN
cord-281793-tj4m01s4	116	18	with	with	IN
cord-281793-tj4m01s4	116	19	the	the	DT
cord-281793-tj4m01s4	116	20	cell	cell	NN
cord-281793-tj4m01s4	116	21	surface	surface	NN
cord-281793-tj4m01s4	116	22	[	[	-LRB-
cord-281793-tj4m01s4	116	23	32	32	CD
cord-281793-tj4m01s4	116	24	]	]	-RRB-
cord-281793-tj4m01s4	116	25	.	.	.
cord-281793-tj4m01s4	117	1	My	-PRON-	PRP$
cord-281793-tj4m01s4	117	2	laboratory	laboratory	NN
cord-281793-tj4m01s4	117	3	research	research	NN
cord-281793-tj4m01s4	117	4	has	have	VBZ
cord-281793-tj4m01s4	117	5	been	be	VBN
cord-281793-tj4m01s4	117	6	focused	focus	VBN
cord-281793-tj4m01s4	117	7	on	on	IN
cord-281793-tj4m01s4	117	8	the	the	DT
cord-281793-tj4m01s4	117	9	biology	biology	NN
cord-281793-tj4m01s4	117	10	of	of	IN
cord-281793-tj4m01s4	117	11	HSPGs	hspg	NNS
cord-281793-tj4m01s4	117	12	,	,	,
cord-281793-tj4m01s4	117	13	in	in	IN
cord-281793-tj4m01s4	117	14	particular	particular	JJ
cord-281793-tj4m01s4	117	15	glypicans	glypican	NNS
cord-281793-tj4m01s4	117	16	,	,	,
cord-281793-tj4m01s4	117	17	and	and	CC
cord-281793-tj4m01s4	117	18	their	-PRON-	PRP$
cord-281793-tj4m01s4	117	19	roles	role	NNS
cord-281793-tj4m01s4	117	20	as	as	IN
cord-281793-tj4m01s4	117	21	targets	target	NNS
cord-281793-tj4m01s4	117	22	in	in	IN
cord-281793-tj4m01s4	117	23	cancer	cancer	NN
cord-281793-tj4m01s4	117	24	therapy	therapy	NN
cord-281793-tj4m01s4	117	25	[	[	-LRB-
cord-281793-tj4m01s4	117	26	33	33	CD
cord-281793-tj4m01s4	117	27	]	]	-RRB-
cord-281793-tj4m01s4	117	28	.	.	.
cord-281793-tj4m01s4	118	1	Using	use	VBG
cord-281793-tj4m01s4	118	2	one	one	CD
cord-281793-tj4m01s4	118	3	of	of	IN
cord-281793-tj4m01s4	118	4	our	-PRON-	PRP$
cord-281793-tj4m01s4	118	5	human	human	JJ
cord-281793-tj4m01s4	118	6	antibodies	antibody	NNS
cord-281793-tj4m01s4	118	7	(	(	-LRB-
cord-281793-tj4m01s4	118	8	HS20	HS20	NNP
cord-281793-tj4m01s4	118	9	)	)	-RRB-
cord-281793-tj4m01s4	118	10	specific	specific	JJ
cord-281793-tj4m01s4	118	11	for	for	IN
cord-281793-tj4m01s4	118	12	heparan	heparan	JJ
cord-281793-tj4m01s4	118	13	sulfate	sulfate	NN
cord-281793-tj4m01s4	118	14	oligosaccharides	oligosaccharide	NNS
cord-281793-tj4m01s4	118	15	with	with	IN
cord-281793-tj4m01s4	118	16	high	high	JJ
cord-281793-tj4m01s4	118	17	affinity	affinity	NN
cord-281793-tj4m01s4	118	18	[	[	-LRB-
cord-281793-tj4m01s4	118	19	34	34	CD
cord-281793-tj4m01s4	118	20	]	]	-RRB-
cord-281793-tj4m01s4	118	21	[	[	-LRB-
cord-281793-tj4m01s4	118	22	35	35	CD
cord-281793-tj4m01s4	118	23	]	]	-RRB-
cord-281793-tj4m01s4	118	24	[	[	-LRB-
cord-281793-tj4m01s4	118	25	36	36	CD
cord-281793-tj4m01s4	118	26	]	]	-RRB-
cord-281793-tj4m01s4	118	27	,	,	,
cord-281793-tj4m01s4	118	28	we	-PRON-	PRP
cord-281793-tj4m01s4	118	29	and	and	CC
cord-281793-tj4m01s4	118	30	collaborators	collaborator	NNS
cord-281793-tj4m01s4	118	31	previously	previously	RB
cord-281793-tj4m01s4	118	32	showed	show	VBD
cord-281793-tj4m01s4	118	33	that	that	IN
cord-281793-tj4m01s4	118	34	the	the	DT
cord-281793-tj4m01s4	118	35	HS20	HS20	NNP
cord-281793-tj4m01s4	118	36	antibody	antibody	NN
cord-281793-tj4m01s4	118	37	can	can	MD
cord-281793-tj4m01s4	118	38	block	block	VB
cord-281793-tj4m01s4	118	39	the	the	DT
cord-281793-tj4m01s4	118	40	attachment	attachment	NN
cord-281793-tj4m01s4	118	41	of	of	IN
cord-281793-tj4m01s4	118	42	pathogenic	pathogenic	JJ
cord-281793-tj4m01s4	118	43	polyomaviruses	polyomaviruse	NNS
cord-281793-tj4m01s4	118	44	on	on	IN
cord-281793-tj4m01s4	118	45	cells	cell	NNS
cord-281793-tj4m01s4	118	46	[	[	-LRB-
cord-281793-tj4m01s4	118	47	37	37	CD
cord-281793-tj4m01s4	118	48	]	]	-RRB-
cord-281793-tj4m01s4	118	49	.	.	.
cord-281793-tj4m01s4	119	1	Interestingly	interestingly	RB
cord-281793-tj4m01s4	119	2	,	,	,
cord-281793-tj4m01s4	119	3	treatment	treatment	NN
cord-281793-tj4m01s4	119	4	of	of	IN
cord-281793-tj4m01s4	119	5	the	the	DT
cord-281793-tj4m01s4	119	6	cells	cell	NNS
cord-281793-tj4m01s4	119	7	with	with	IN
cord-281793-tj4m01s4	119	8	heparinase	heparinase	NN
cord-281793-tj4m01s4	119	9	or	or	CC
cord-281793-tj4m01s4	119	10	exogenous	exogenous	JJ
cord-281793-tj4m01s4	119	11	heparin	heparin	NN
cord-281793-tj4m01s4	119	12	prevents	prevent	VBZ
cord-281793-tj4m01s4	119	13	the	the	DT
cord-281793-tj4m01s4	119	14	binding	binding	NN
cord-281793-tj4m01s4	119	15	of	of	IN
cord-281793-tj4m01s4	119	16	the	the	DT
cord-281793-tj4m01s4	119	17	S	S	NNP
cord-281793-tj4m01s4	119	18	protein	protein	NN
cord-281793-tj4m01s4	119	19	to	to	TO
cord-281793-tj4m01s4	119	20	host	host	VB
cord-281793-tj4m01s4	119	21	cells	cell	NNS
cord-281793-tj4m01s4	119	22	and	and	CC
cord-281793-tj4m01s4	119	23	inhibits	inhibit	VBZ
cord-281793-tj4m01s4	119	24	SARS	SARS	NNP
cord-281793-tj4m01s4	119	25	pseudovirus	pseudovirus	NNP
cord-281793-tj4m01s4	119	26	infection	infection	NN
cord-281793-tj4m01s4	119	27	[	[	-LRB-
cord-281793-tj4m01s4	119	28	32	32	CD
cord-281793-tj4m01s4	119	29	]	]	-RRB-
cord-281793-tj4m01s4	119	30	,	,	,
cord-281793-tj4m01s4	119	31	suggesting	suggest	VBG
cord-281793-tj4m01s4	119	32	that	that	IN
cord-281793-tj4m01s4	119	33	in	in	IN
cord-281793-tj4m01s4	119	34	addition	addition	NN
cord-281793-tj4m01s4	119	35	to	to	IN
cord-281793-tj4m01s4	119	36	ACE2	ACE2	NNP
cord-281793-tj4m01s4	119	37	,	,	,
cord-281793-tj4m01s4	119	38	HSPGs	hspg	NNS
cord-281793-tj4m01s4	119	39	might	may	MD
cord-281793-tj4m01s4	119	40	be	be	VB
cord-281793-tj4m01s4	119	41	essential	essential	JJ
cord-281793-tj4m01s4	119	42	for	for	IN
cord-281793-tj4m01s4	119	43	SARS	SARS	NNP
cord-281793-tj4m01s4	119	44	-	-	HYPH
cord-281793-tj4m01s4	119	45	CoV	CoV	NNP
cord-281793-tj4m01s4	119	46	entry	entry	NN
cord-281793-tj4m01s4	119	47	into	into	IN
cord-281793-tj4m01s4	119	48	host	host	NN
cord-281793-tj4m01s4	119	49	cells	cell	NNS
cord-281793-tj4m01s4	119	50	.	.	.
cord-281793-tj4m01s4	120	1	Blocking	block	VBG
cord-281793-tj4m01s4	120	2	the	the	DT
cord-281793-tj4m01s4	120	3	HSPGs	hspg	NNS
cord-281793-tj4m01s4	120	4	on	on	IN
cord-281793-tj4m01s4	120	5	human	human	JJ
cord-281793-tj4m01s4	120	6	cells	cell	NNS
cord-281793-tj4m01s4	120	7	by	by	IN
cord-281793-tj4m01s4	120	8	therapeutic	therapeutic	JJ
cord-281793-tj4m01s4	120	9	antibodies	antibody	NNS
cord-281793-tj4m01s4	120	10	is	be	VBZ
cord-281793-tj4m01s4	120	11	worth	worth	JJ
cord-281793-tj4m01s4	120	12	investigating	investigate	VBG
cord-281793-tj4m01s4	120	13	as	as	IN
cord-281793-tj4m01s4	120	14	another	another	DT
cord-281793-tj4m01s4	120	15	potential	potential	JJ
cord-281793-tj4m01s4	120	16	strategy	strategy	NN
cord-281793-tj4m01s4	120	17	for	for	IN
cord-281793-tj4m01s4	120	18	treating	treat	VBG
cord-281793-tj4m01s4	120	19	COVID-19	covid-19	NN
cord-281793-tj4m01s4	120	20	.	.	.
cord-281793-tj4m01s4	121	1	Many	many	JJ
cord-281793-tj4m01s4	121	2	antibodies	antibody	NNS
cord-281793-tj4m01s4	121	3	capable	capable	JJ
cord-281793-tj4m01s4	121	4	of	of	IN
cord-281793-tj4m01s4	121	5	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	121	6	specifically	specifically	RB
cord-281793-tj4m01s4	121	7	either	either	DT
cord-281793-tj4m01s4	121	8	SARS	SARS	NNP
cord-281793-tj4m01s4	121	9	-	-	HYPH
cord-281793-tj4m01s4	121	10	CoV	CoV	NNP
cord-281793-tj4m01s4	121	11	or	or	CC
cord-281793-tj4m01s4	121	12	SARS	SARS	NNP
cord-281793-tj4m01s4	121	13	-	-	HYPH
cord-281793-tj4m01s4	121	14	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	121	15	,	,	,
cord-281793-tj4m01s4	121	16	but	but	CC
cord-281793-tj4m01s4	121	17	not	not	RB
cord-281793-tj4m01s4	121	18	both	both	DT
cord-281793-tj4m01s4	121	19	,	,	,
cord-281793-tj4m01s4	121	20	have	have	VBP
cord-281793-tj4m01s4	121	21	been	be	VBN
cord-281793-tj4m01s4	121	22	identified	identify	VBN
cord-281793-tj4m01s4	121	23	and	and	CC
cord-281793-tj4m01s4	121	24	reported	report	VBN
cord-281793-tj4m01s4	121	25	through	through	IN
cord-281793-tj4m01s4	121	26	many	many	JJ
cord-281793-tj4m01s4	121	27	methodologies	methodology	NNS
cord-281793-tj4m01s4	121	28	.	.	.
cord-281793-tj4m01s4	122	1	A	a	DT
cord-281793-tj4m01s4	122	2	very	very	RB
cord-281793-tj4m01s4	122	3	few	few	JJ
cord-281793-tj4m01s4	122	4	and	and	CC
cord-281793-tj4m01s4	122	5	very	very	RB
cord-281793-tj4m01s4	122	6	special	special	JJ
cord-281793-tj4m01s4	122	7	SARS	SARS	NNP
cord-281793-tj4m01s4	122	8	-	-	HYPH
cord-281793-tj4m01s4	122	9	CoV	CoV	NNP
cord-281793-tj4m01s4	122	10	and	and	CC
cord-281793-tj4m01s4	122	11	SARS	SARS	NNP
cord-281793-tj4m01s4	122	12	-	-	HYPH
cord-281793-tj4m01s4	122	13	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	122	14	crossneutralizing	crossneutralize	VBG
cord-281793-tj4m01s4	122	15	antibodies	antibody	NNS
cord-281793-tj4m01s4	122	16	have	have	VBP
cord-281793-tj4m01s4	122	17	also	also	RB
cord-281793-tj4m01s4	122	18	been	be	VBN
cord-281793-tj4m01s4	122	19	documented	document	VBN
cord-281793-tj4m01s4	122	20	,	,	,
cord-281793-tj4m01s4	122	21	including	include	VBG
cord-281793-tj4m01s4	122	22	47D11	47d11	CD
cord-281793-tj4m01s4	122	23	,	,	,
cord-281793-tj4m01s4	122	24	S309	S309	NNP
cord-281793-tj4m01s4	122	25	,	,	,
cord-281793-tj4m01s4	122	26	and	and	CC
cord-281793-tj4m01s4	122	27	VHH-72	VHH-72	NNP
cord-281793-tj4m01s4	122	28	,	,	,
cord-281793-tj4m01s4	122	29	among	among	IN
cord-281793-tj4m01s4	122	30	which	which	WDT
cord-281793-tj4m01s4	122	31	the	the	DT
cord-281793-tj4m01s4	122	32	former	former	JJ
cord-281793-tj4m01s4	122	33	two	two	CD
cord-281793-tj4m01s4	122	34	,	,	,
cord-281793-tj4m01s4	122	35	which	which	WDT
cord-281793-tj4m01s4	122	36	are	be	VBP
cord-281793-tj4m01s4	122	37	human	human	JJ
cord-281793-tj4m01s4	122	38	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	122	39	antibodies	antibody	NNS
cord-281793-tj4m01s4	122	40	,	,	,
cord-281793-tj4m01s4	122	41	are	be	VBP
cord-281793-tj4m01s4	122	42	ACE2	ACE2	NNP
cord-281793-tj4m01s4	122	43	nonblockers	nonblocker	NNS
cord-281793-tj4m01s4	122	44	,	,	,
cord-281793-tj4m01s4	122	45	whereas	whereas	IN
cord-281793-tj4m01s4	122	46	the	the	DT
cord-281793-tj4m01s4	122	47	third	third	JJ
cord-281793-tj4m01s4	122	48	one	one	NN
cord-281793-tj4m01s4	122	49	,	,	,
cord-281793-tj4m01s4	122	50	which	which	WDT
cord-281793-tj4m01s4	122	51	is	be	VBZ
cord-281793-tj4m01s4	122	52	a	a	DT
cord-281793-tj4m01s4	122	53	llama	llama	NN
cord-281793-tj4m01s4	122	54	single	single	JJ
cord-281793-tj4m01s4	122	55	domain	domain	NN
cord-281793-tj4m01s4	122	56	antibody	antibody	NN
cord-281793-tj4m01s4	122	57	,	,	,
cord-281793-tj4m01s4	122	58	is	be	VBZ
cord-281793-tj4m01s4	122	59	an	an	DT
cord-281793-tj4m01s4	122	60	ACE2	ACE2	NNP
cord-281793-tj4m01s4	122	61	blocker	blocker	NN
cord-281793-tj4m01s4	122	62	.	.	.
cord-281793-tj4m01s4	123	1	Competitive	competitive	JJ
cord-281793-tj4m01s4	123	2	phage	phage	NN
cord-281793-tj4m01s4	123	3	display	display	NN
cord-281793-tj4m01s4	123	4	panning	panning	NN
cord-281793-tj4m01s4	123	5	might	may	MD
cord-281793-tj4m01s4	123	6	be	be	VB
cord-281793-tj4m01s4	123	7	a	a	DT
cord-281793-tj4m01s4	123	8	new	new	JJ
cord-281793-tj4m01s4	123	9	way	way	NN
cord-281793-tj4m01s4	123	10	to	to	TO
cord-281793-tj4m01s4	123	11	identify	identify	VB
cord-281793-tj4m01s4	123	12	both	both	DT
cord-281793-tj4m01s4	123	13	ACE2	ACE2	NNP
cord-281793-tj4m01s4	123	14	blockers	blocker	NNS
cord-281793-tj4m01s4	123	15	and	and	CC
cord-281793-tj4m01s4	123	16	nonblockers	nonblocker	NNS
cord-281793-tj4m01s4	123	17	.	.	.
cord-281793-tj4m01s4	124	1	Even	even	RB
cord-281793-tj4m01s4	124	2	though	though	IN
cord-281793-tj4m01s4	124	3	Zeng	Zeng	NNP
cord-281793-tj4m01s4	124	4	et	et	FW
cord-281793-tj4m01s4	124	5	al	al	NNP
cord-281793-tj4m01s4	124	6	.	.	.
cord-281793-tj4m01s4	125	1	only	only	RB
cord-281793-tj4m01s4	125	2	reported	report	VBD
cord-281793-tj4m01s4	125	3	the	the	DT
cord-281793-tj4m01s4	125	4	identification	identification	NN
cord-281793-tj4m01s4	125	5	of	of	IN
cord-281793-tj4m01s4	125	6	one	one	CD
cord-281793-tj4m01s4	125	7	antibody	antibody	NN
cord-281793-tj4m01s4	125	8	,	,	,
cord-281793-tj4m01s4	125	9	rRBD-15	rrbd-15	CD
cord-281793-tj4m01s4	125	10	,	,	,
cord-281793-tj4m01s4	125	11	that	that	WDT
cord-281793-tj4m01s4	125	12	blocked	block	VBD
cord-281793-tj4m01s4	125	13	ACE2	ACE2	NNP
cord-281793-tj4m01s4	125	14	and	and	CC
cord-281793-tj4m01s4	125	15	neutralized	neutralize	VBN
cord-281793-tj4m01s4	125	16	SARS	SARS	NNP
cord-281793-tj4m01s4	125	17	-	-	HYPH
cord-281793-tj4m01s4	125	18	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	125	19	[	[	-LRB-
cord-281793-tj4m01s4	125	20	5	5	CD
cord-281793-tj4m01s4	125	21	]	]	-RRB-
cord-281793-tj4m01s4	125	22	,	,	,
cord-281793-tj4m01s4	125	23	the	the	DT
cord-281793-tj4m01s4	125	24	same	same	JJ
cord-281793-tj4m01s4	125	25	phage	phage	NN
cord-281793-tj4m01s4	125	26	display	display	NN
cord-281793-tj4m01s4	125	27	competitive	competitive	JJ
cord-281793-tj4m01s4	125	28	panning	panning	NN
cord-281793-tj4m01s4	125	29	strategy	strategy	NN
cord-281793-tj4m01s4	125	30	could	could	MD
cord-281793-tj4m01s4	125	31	also	also	RB
cord-281793-tj4m01s4	125	32	be	be	VB
cord-281793-tj4m01s4	125	33	used	use	VBN
cord-281793-tj4m01s4	125	34	to	to	TO
cord-281793-tj4m01s4	125	35	identify	identify	VB
cord-281793-tj4m01s4	125	36	antibodies	antibody	NNS
cord-281793-tj4m01s4	125	37	that	that	WDT
cord-281793-tj4m01s4	125	38	do	do	VBP
cord-281793-tj4m01s4	125	39	not	not	RB
cord-281793-tj4m01s4	125	40	block	block	VB
cord-281793-tj4m01s4	125	41	the	the	DT
cord-281793-tj4m01s4	125	42	interaction	interaction	NN
cord-281793-tj4m01s4	125	43	between	between	IN
cord-281793-tj4m01s4	125	44	S	S	NNP
cord-281793-tj4m01s4	125	45	protein	protein	NN
cord-281793-tj4m01s4	125	46	and	and	CC
cord-281793-tj4m01s4	125	47	ACE2	ACE2	NNP
cord-281793-tj4m01s4	125	48	yet	yet	RB
cord-281793-tj4m01s4	125	49	still	still	RB
cord-281793-tj4m01s4	125	50	neutralize	neutralize	VB
cord-281793-tj4m01s4	125	51	viral	viral	JJ
cord-281793-tj4m01s4	125	52	infections	infection	NNS
cord-281793-tj4m01s4	125	53	.	.	.
cord-281793-tj4m01s4	126	1	More	more	RBR
cord-281793-tj4m01s4	126	2	importantly	importantly	RB
cord-281793-tj4m01s4	126	3	,	,	,
cord-281793-tj4m01s4	126	4	with	with	IN
cord-281793-tj4m01s4	126	5	S	s	NN
cord-281793-tj4m01s4	126	6	proteins	protein	NNS
cord-281793-tj4m01s4	126	7	of	of	IN
cord-281793-tj4m01s4	126	8	both	both	DT
cord-281793-tj4m01s4	126	9	SARS	SARS	NNP
cord-281793-tj4m01s4	126	10	-	-	HYPH
cord-281793-tj4m01s4	126	11	CoV	CoV	NNP
cord-281793-tj4m01s4	126	12	and	and	CC
cord-281793-tj4m01s4	126	13	SARS	SARS	NNP
cord-281793-tj4m01s4	126	14	-	-	HYPH
cord-281793-tj4m01s4	126	15	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	126	16	as	as	IN
cord-281793-tj4m01s4	126	17	competitors	competitor	NNS
cord-281793-tj4m01s4	126	18	,	,	,
cord-281793-tj4m01s4	126	19	this	this	DT
cord-281793-tj4m01s4	126	20	competitive	competitive	JJ
cord-281793-tj4m01s4	126	21	panning	panning	NN
cord-281793-tj4m01s4	126	22	strategy	strategy	NN
cord-281793-tj4m01s4	126	23	could	could	MD
cord-281793-tj4m01s4	126	24	be	be	VB
cord-281793-tj4m01s4	126	25	utilized	utilize	VBN
cord-281793-tj4m01s4	126	26	to	to	TO
cord-281793-tj4m01s4	126	27	identify	identify	VB
cord-281793-tj4m01s4	126	28	both	both	DT
cord-281793-tj4m01s4	126	29	ACE2	ACE2	NNP
cord-281793-tj4m01s4	126	30	blocking	blocking	NN
cord-281793-tj4m01s4	126	31	and	and	CC
cord-281793-tj4m01s4	126	32	nonblocking	nonblocking	JJ
cord-281793-tj4m01s4	126	33	antibodies	antibody	NNS
cord-281793-tj4m01s4	126	34	against	against	IN
cord-281793-tj4m01s4	126	35	both	both	DT
cord-281793-tj4m01s4	126	36	viruses	virus	NNS
cord-281793-tj4m01s4	126	37	with	with	IN
cord-281793-tj4m01s4	126	38	functional	functional	JJ
cord-281793-tj4m01s4	126	39	profiles	profile	NNS
cord-281793-tj4m01s4	126	40	similar	similar	JJ
cord-281793-tj4m01s4	126	41	to	to	IN
cord-281793-tj4m01s4	126	42	47D11	47d11	CD
cord-281793-tj4m01s4	126	43	,	,	,
cord-281793-tj4m01s4	126	44	S309	S309	NNP
cord-281793-tj4m01s4	126	45	,	,	,
cord-281793-tj4m01s4	126	46	and	and	CC
cord-281793-tj4m01s4	126	47	VHH-72	VHH-72	NNP
cord-281793-tj4m01s4	126	48	,	,	,
cord-281793-tj4m01s4	126	49	respectively	respectively	RB
cord-281793-tj4m01s4	126	50	.	.	.
cord-281793-tj4m01s4	127	1	In	in	IN
cord-281793-tj4m01s4	127	2	the	the	DT
cord-281793-tj4m01s4	127	3	last	last	JJ
cord-281793-tj4m01s4	127	4	20	20	CD
cord-281793-tj4m01s4	127	5	years	year	NNS
cord-281793-tj4m01s4	127	6	,	,	,
cord-281793-tj4m01s4	127	7	human	human	JJ
cord-281793-tj4m01s4	127	8	coronaviruses	coronaviruse	NNS
cord-281793-tj4m01s4	127	9	have	have	VBP
cord-281793-tj4m01s4	127	10	infected	infect	VBN
cord-281793-tj4m01s4	127	11	humans	human	NNS
cord-281793-tj4m01s4	127	12	and	and	CC
cord-281793-tj4m01s4	127	13	causes	cause	VBZ
cord-281793-tj4m01s4	127	14	three	three	CD
cord-281793-tj4m01s4	127	15	major	major	JJ
cord-281793-tj4m01s4	127	16	outbreaks	outbreak	NNS
cord-281793-tj4m01s4	127	17	due	due	JJ
cord-281793-tj4m01s4	127	18	to	to	IN
cord-281793-tj4m01s4	127	19	SARS	SARS	NNP
cord-281793-tj4m01s4	127	20	-	-	HYPH
cord-281793-tj4m01s4	127	21	CoV	CoV	NNP
cord-281793-tj4m01s4	127	22	,	,	,
cord-281793-tj4m01s4	127	23	MERS	MERS	NNP
cord-281793-tj4m01s4	127	24	-	-	HYPH
cord-281793-tj4m01s4	127	25	CoV	CoV	NNP
cord-281793-tj4m01s4	127	26	,	,	,
cord-281793-tj4m01s4	127	27	and	and	CC
cord-281793-tj4m01s4	127	28	SARS	SARS	NNP
cord-281793-tj4m01s4	127	29	-	-	HYPH
cord-281793-tj4m01s4	127	30	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	127	31	.	.	.
cord-281793-tj4m01s4	128	1	An	an	DT
cord-281793-tj4m01s4	128	2	urgent	urgent	JJ
cord-281793-tj4m01s4	128	3	and	and	CC
cord-281793-tj4m01s4	128	4	important	important	JJ
cord-281793-tj4m01s4	128	5	challenge	challenge	NN
cord-281793-tj4m01s4	128	6	in	in	IN
cord-281793-tj4m01s4	128	7	modern	modern	JJ
cord-281793-tj4m01s4	128	8	medicine	medicine	NN
cord-281793-tj4m01s4	128	9	is	be	VBZ
cord-281793-tj4m01s4	128	10	whether	whether	IN
cord-281793-tj4m01s4	128	11	we	-PRON-	PRP
cord-281793-tj4m01s4	128	12	could	could	MD
cord-281793-tj4m01s4	128	13	identify	identify	VB
cord-281793-tj4m01s4	128	14	a	a	DT
cord-281793-tj4m01s4	128	15	so	so	RB
cord-281793-tj4m01s4	128	16	-	-	HYPH
cord-281793-tj4m01s4	128	17	called	call	VBN
cord-281793-tj4m01s4	128	18	"	"	``
cord-281793-tj4m01s4	128	19	universal	universal	JJ
cord-281793-tj4m01s4	128	20	"	"	''
cord-281793-tj4m01s4	128	21	target	target	NN
cord-281793-tj4m01s4	128	22	or	or	CC
cord-281793-tj4m01s4	128	23	strategy	strategy	NN
cord-281793-tj4m01s4	128	24	for	for	IN
cord-281793-tj4m01s4	128	25	inhibiting	inhibit	VBG
cord-281793-tj4m01s4	128	26	SARSr	SARSr	NNP
cord-281793-tj4m01s4	128	27	-	-	HYPH
cord-281793-tj4m01s4	128	28	CoV	cov	NN
cord-281793-tj4m01s4	128	29	or	or	CC
cord-281793-tj4m01s4	128	30	even	even	RB
cord-281793-tj4m01s4	128	31	all	all	DT
cord-281793-tj4m01s4	128	32	coronaviruses	coronaviruse	NNS
cord-281793-tj4m01s4	128	33	.	.	.
cord-281793-tj4m01s4	129	1	The	the	DT
cord-281793-tj4m01s4	129	2	molecular	molecular	JJ
cord-281793-tj4m01s4	129	3	mechanisms	mechanism	NNS
cord-281793-tj4m01s4	129	4	of	of	IN
cord-281793-tj4m01s4	129	5	SARS	SARS	NNP
cord-281793-tj4m01s4	129	6	-	-	HYPH
cord-281793-tj4m01s4	129	7	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	129	8	infection	infection	NN
cord-281793-tj4m01s4	129	9	are	be	VBP
cord-281793-tj4m01s4	129	10	not	not	RB
cord-281793-tj4m01s4	129	11	yet	yet	RB
cord-281793-tj4m01s4	129	12	fully	fully	RB
cord-281793-tj4m01s4	129	13	understood	understand	VBN
cord-281793-tj4m01s4	129	14	.	.	.
cord-281793-tj4m01s4	130	1	More	More	JJR
cord-281793-tj4m01s4	130	2	research	research	NN
cord-281793-tj4m01s4	130	3	on	on	IN
cord-281793-tj4m01s4	130	4	the	the	DT
cord-281793-tj4m01s4	130	5	SARS	SARS	NNP
cord-281793-tj4m01s4	130	6	-	-	HYPH
cord-281793-tj4m01s4	130	7	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	130	8	biology	biology	NN
cord-281793-tj4m01s4	130	9	is	be	VBZ
cord-281793-tj4m01s4	130	10	urgently	urgently	RB
cord-281793-tj4m01s4	130	11	needed	need	VBN
cord-281793-tj4m01s4	130	12	.	.	.
cord-281793-tj4m01s4	131	1	Current	current	JJ
cord-281793-tj4m01s4	131	2	challenges	challenge	NNS
cord-281793-tj4m01s4	131	3	in	in	IN
cord-281793-tj4m01s4	131	4	developing	develop	VBG
cord-281793-tj4m01s4	131	5	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	131	6	antibodies	antibody	NNS
cord-281793-tj4m01s4	131	7	against	against	IN
cord-281793-tj4m01s4	131	8	SARS	SARS	NNP
cord-281793-tj4m01s4	131	9	-	-	HYPH
cord-281793-tj4m01s4	131	10	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	131	11	include	include	VBP
cord-281793-tj4m01s4	131	12	mutations	mutation	NNS
cord-281793-tj4m01s4	131	13	in	in	IN
cord-281793-tj4m01s4	131	14	less	less	RBR
cord-281793-tj4m01s4	131	15	conserved	conserved	JJ
cord-281793-tj4m01s4	131	16	region	region	NN
cord-281793-tj4m01s4	131	17	of	of	IN
cord-281793-tj4m01s4	131	18	S1	s1	NN
cord-281793-tj4m01s4	131	19	subunit	subunit	NN
cord-281793-tj4m01s4	131	20	,	,	,
cord-281793-tj4m01s4	131	21	possibly	possibly	RB
cord-281793-tj4m01s4	131	22	antigen	antigen	NNP
cord-281793-tj4m01s4	131	23	drift	drift	NN
cord-281793-tj4m01s4	131	24	,	,	,
cord-281793-tj4m01s4	131	25	immunodominant	immunodominant	JJ
cord-281793-tj4m01s4	131	26	epitope	epitope	NN
cord-281793-tj4m01s4	131	27	,	,	,
cord-281793-tj4m01s4	131	28	ADE	ADE	NNP
cord-281793-tj4m01s4	131	29	potentially	potentially	RB
cord-281793-tj4m01s4	131	30	induced	induce	VBN
cord-281793-tj4m01s4	131	31	by	by	IN
cord-281793-tj4m01s4	131	32	nonneutralizing	nonneutralize	VBG
cord-281793-tj4m01s4	131	33	antibodies	antibody	NNS
cord-281793-tj4m01s4	131	34	,	,	,
cord-281793-tj4m01s4	131	35	or	or	CC
cord-281793-tj4m01s4	131	36	increased	increase	VBN
cord-281793-tj4m01s4	131	37	affinity	affinity	NN
cord-281793-tj4m01s4	131	38	of	of	IN
cord-281793-tj4m01s4	131	39	viral	viral	JJ
cord-281793-tj4m01s4	131	40	S	s	NN
cord-281793-tj4m01s4	131	41	protein	protein	NN
cord-281793-tj4m01s4	131	42	for	for	IN
cord-281793-tj4m01s4	131	43	ACE2	ACE2	NNP
cord-281793-tj4m01s4	131	44	[	[	-LRB-
cord-281793-tj4m01s4	131	45	26	26	CD
cord-281793-tj4m01s4	131	46	]	]	-RRB-
cord-281793-tj4m01s4	131	47	.	.	.
cord-281793-tj4m01s4	132	1	It	-PRON-	PRP
cord-281793-tj4m01s4	132	2	is	be	VBZ
cord-281793-tj4m01s4	132	3	important	important	JJ
cord-281793-tj4m01s4	132	4	to	to	TO
cord-281793-tj4m01s4	132	5	identify	identify	VB
cord-281793-tj4m01s4	132	6	and	and	CC
cord-281793-tj4m01s4	132	7	develop	develop	VB
cord-281793-tj4m01s4	132	8	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	132	9	antibodies	antibody	NNS
cord-281793-tj4m01s4	132	10	,	,	,
cord-281793-tj4m01s4	132	11	such	such	JJ
cord-281793-tj4m01s4	132	12	as	as	IN
cord-281793-tj4m01s4	132	13	47D11	47d11	CD
cord-281793-tj4m01s4	132	14	,	,	,
cord-281793-tj4m01s4	132	15	S309	S309	NNP
cord-281793-tj4m01s4	132	16	,	,	,
cord-281793-tj4m01s4	132	17	and	and	CC
cord-281793-tj4m01s4	132	18	VHH-72	VHH-72	NNP
cord-281793-tj4m01s4	132	19	,	,	,
cord-281793-tj4m01s4	132	20	against	against	IN
cord-281793-tj4m01s4	132	21	highly	highly	RB
cord-281793-tj4m01s4	132	22	conserved	conserve	VBN
cord-281793-tj4m01s4	132	23	region	region	NN
cord-281793-tj4m01s4	132	24	of	of	IN
cord-281793-tj4m01s4	132	25	RBD	RBD	NNP
cord-281793-tj4m01s4	132	26	or	or	CC
cord-281793-tj4m01s4	132	27	S1	S1	NNP
cord-281793-tj4m01s4	132	28	,	,	,
cord-281793-tj4m01s4	132	29	to	to	TO
cord-281793-tj4m01s4	132	30	combat	combat	VB
cord-281793-tj4m01s4	132	31	not	not	RB
cord-281793-tj4m01s4	132	32	only	only	RB
cord-281793-tj4m01s4	132	33	various	various	JJ
cord-281793-tj4m01s4	132	34	strains	strain	NNS
cord-281793-tj4m01s4	132	35	of	of	IN
cord-281793-tj4m01s4	132	36	SARS	SARS	NNP
cord-281793-tj4m01s4	132	37	-	-	HYPH
cord-281793-tj4m01s4	132	38	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	132	39	but	but	CC
cord-281793-tj4m01s4	132	40	also	also	RB
cord-281793-tj4m01s4	132	41	broadly	broadly	RB
cord-281793-tj4m01s4	132	42	against	against	IN
cord-281793-tj4m01s4	132	43	other	other	JJ
cord-281793-tj4m01s4	132	44	SARSr	SARSr	NNS
cord-281793-tj4m01s4	132	45	-	-	HYPH
cord-281793-tj4m01s4	132	46	CoVs	CoVs	NNP
cord-281793-tj4m01s4	132	47	.	.	.
cord-281793-tj4m01s4	133	1	Furthermore	furthermore	RB
cord-281793-tj4m01s4	133	2	,	,	,
cord-281793-tj4m01s4	133	3	a	a	DT
cord-281793-tj4m01s4	133	4	single	single	JJ
cord-281793-tj4m01s4	133	5	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	133	6	antibody	antibody	NN
cord-281793-tj4m01s4	133	7	therapy	therapy	NN
cord-281793-tj4m01s4	133	8	might	may	MD
cord-281793-tj4m01s4	133	9	not	not	RB
cord-281793-tj4m01s4	133	10	be	be	VB
cord-281793-tj4m01s4	133	11	enough	enough	JJ
cord-281793-tj4m01s4	133	12	.	.	.
cord-281793-tj4m01s4	134	1	There	there	EX
cord-281793-tj4m01s4	134	2	might	may	MD
cord-281793-tj4m01s4	134	3	be	be	VB
cord-281793-tj4m01s4	134	4	different	different	JJ
cord-281793-tj4m01s4	134	5	strains	strain	NNS
cord-281793-tj4m01s4	134	6	of	of	IN
cord-281793-tj4m01s4	134	7	the	the	DT
cord-281793-tj4m01s4	134	8	virus	virus	NN
cord-281793-tj4m01s4	134	9	that	that	WDT
cord-281793-tj4m01s4	134	10	can	can	MD
cord-281793-tj4m01s4	134	11	not	not	RB
cord-281793-tj4m01s4	134	12	be	be	VB
cord-281793-tj4m01s4	134	13	recognized	recognize	VBN
cord-281793-tj4m01s4	134	14	by	by	IN
cord-281793-tj4m01s4	134	15	the	the	DT
cord-281793-tj4m01s4	134	16	antibody	antibody	NN
cord-281793-tj4m01s4	134	17	.	.	.
cord-281793-tj4m01s4	135	1	Mutations	mutation	NNS
cord-281793-tj4m01s4	135	2	in	in	IN
cord-281793-tj4m01s4	135	3	the	the	DT
cord-281793-tj4m01s4	135	4	virus	virus	NN
cord-281793-tj4m01s4	135	5	can	can	MD
cord-281793-tj4m01s4	135	6	lead	lead	VB
cord-281793-tj4m01s4	135	7	to	to	TO
cord-281793-tj4m01s4	135	8	escape	escape	VB
cord-281793-tj4m01s4	135	9	variants	variant	NNS
cord-281793-tj4m01s4	135	10	[	[	-LRB-
cord-281793-tj4m01s4	135	11	38	38	CD
cord-281793-tj4m01s4	135	12	]	]	-RRB-
cord-281793-tj4m01s4	135	13	.	.	.
cord-281793-tj4m01s4	136	1	Multiple	multiple	JJ
cord-281793-tj4m01s4	136	2	strategies	strategy	NNS
cord-281793-tj4m01s4	136	3	and	and	CC
cord-281793-tj4m01s4	136	4	combination	combination	NN
cord-281793-tj4m01s4	136	5	of	of	IN
cord-281793-tj4m01s4	136	6	multiple	multiple	JJ
cord-281793-tj4m01s4	136	7	mechanisms	mechanism	NNS
cord-281793-tj4m01s4	136	8	are	be	VBP
cord-281793-tj4m01s4	136	9	highly	highly	RB
cord-281793-tj4m01s4	136	10	expected	expect	VBN
cord-281793-tj4m01s4	136	11	as	as	IN
cord-281793-tj4m01s4	136	12	described	describe	VBN
cord-281793-tj4m01s4	136	13	in	in	IN
cord-281793-tj4m01s4	136	14	MERS	MERS	NNP
cord-281793-tj4m01s4	136	15	[	[	-LRB-
cord-281793-tj4m01s4	136	16	39	39	CD
cord-281793-tj4m01s4	136	17	]	]	-RRB-
cord-281793-tj4m01s4	136	18	and	and	CC
cord-281793-tj4m01s4	136	19	SARS	SARS	NNP
cord-281793-tj4m01s4	136	20	[	[	-LRB-
cord-281793-tj4m01s4	136	21	38	38	CD
cord-281793-tj4m01s4	136	22	]	]	-RRB-
cord-281793-tj4m01s4	136	23	antibody	antibody	NN
cord-281793-tj4m01s4	136	24	development	development	NN
cord-281793-tj4m01s4	136	25	.	.	.
cord-281793-tj4m01s4	137	1	A	a	DT
cord-281793-tj4m01s4	137	2	combination	combination	NN
cord-281793-tj4m01s4	137	3	of	of	IN
cord-281793-tj4m01s4	137	4	two	two	CD
cord-281793-tj4m01s4	137	5	(	(	-LRB-
cord-281793-tj4m01s4	137	6	or	or	CC
cord-281793-tj4m01s4	137	7	more	more	JJR
cord-281793-tj4m01s4	137	8	)	)	-RRB-
cord-281793-tj4m01s4	137	9	antibodies	antibody	NNS
cord-281793-tj4m01s4	137	10	that	that	WDT
cord-281793-tj4m01s4	137	11	recognize	recognize	VBP
cord-281793-tj4m01s4	137	12	different	different	JJ
cord-281793-tj4m01s4	137	13	parts	part	NNS
cord-281793-tj4m01s4	137	14	including	include	VBG
cord-281793-tj4m01s4	137	15	both	both	CC
cord-281793-tj4m01s4	137	16	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	137	17	and	and	CC
cord-281793-tj4m01s4	137	18	nonneutralizing	nonneutralize	VBG
cord-281793-tj4m01s4	137	19	epitopes	epitope	NNS
cord-281793-tj4m01s4	137	20	(	(	-LRB-
cord-281793-tj4m01s4	137	21	e.g.	e.g.	RB
cord-281793-tj4m01s4	137	22	,	,	,
cord-281793-tj4m01s4	137	23	RBD	RBD	NNP
cord-281793-tj4m01s4	137	24	,	,	,
cord-281793-tj4m01s4	137	25	NTD	NTD	NNP
cord-281793-tj4m01s4	137	26	,	,	,
cord-281793-tj4m01s4	137	27	HR	HR	NNP
cord-281793-tj4m01s4	137	28	,	,	,
cord-281793-tj4m01s4	137	29	and	and	CC
cord-281793-tj4m01s4	137	30	glycan	glycan	NN
cord-281793-tj4m01s4	137	31	)	)	-RRB-
cord-281793-tj4m01s4	137	32	of	of	IN
cord-281793-tj4m01s4	137	33	the	the	DT
cord-281793-tj4m01s4	137	34	viral	viral	JJ
cord-281793-tj4m01s4	137	35	surface	surface	NN
cord-281793-tj4m01s4	137	36	that	that	WDT
cord-281793-tj4m01s4	137	37	interact	interact	VBP
cord-281793-tj4m01s4	137	38	with	with	IN
cord-281793-tj4m01s4	137	39	human	human	JJ
cord-281793-tj4m01s4	137	40	cells	cell	NNS
cord-281793-tj4m01s4	137	41	might	may	MD
cord-281793-tj4m01s4	137	42	be	be	VB
cord-281793-tj4m01s4	137	43	the	the	DT
cord-281793-tj4m01s4	137	44	most	most	RBS
cord-281793-tj4m01s4	137	45	effective	effective	JJ
cord-281793-tj4m01s4	137	46	.	.	.
cord-281793-tj4m01s4	138	1	Future	future	JJ
cord-281793-tj4m01s4	138	2	therapeutic	therapeutic	JJ
cord-281793-tj4m01s4	138	3	applications	application	NNS
cord-281793-tj4m01s4	138	4	could	could	MD
cord-281793-tj4m01s4	138	5	include	include	VB
cord-281793-tj4m01s4	138	6	cocktail	cocktail	NN
cord-281793-tj4m01s4	138	7	therapy	therapy	NN
cord-281793-tj4m01s4	138	8	by	by	IN
cord-281793-tj4m01s4	138	9	combining	combine	VBG
cord-281793-tj4m01s4	138	10	Early	early	JJ
cord-281793-tj4m01s4	138	11	transmission	transmission	NN
cord-281793-tj4m01s4	138	12	dynamics	dynamic	NNS
cord-281793-tj4m01s4	138	13	in	in	IN
cord-281793-tj4m01s4	138	14	Wuhan	Wuhan	NNP
cord-281793-tj4m01s4	138	15	,	,	,
cord-281793-tj4m01s4	138	16	China	China	NNP
cord-281793-tj4m01s4	138	17	,	,	,
cord-281793-tj4m01s4	138	18	of	of	IN
cord-281793-tj4m01s4	138	19	novel	novel	JJ
cord-281793-tj4m01s4	138	20	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	138	21	-	-	HYPH
cord-281793-tj4m01s4	138	22	infected	infect	VBN
cord-281793-tj4m01s4	138	23	pneumonia	pneumonia	NN
cord-281793-tj4m01s4	138	24	Clinical	clinical	JJ
cord-281793-tj4m01s4	138	25	course	course	NN
cord-281793-tj4m01s4	138	26	and	and	CC
cord-281793-tj4m01s4	138	27	risk	risk	NN
cord-281793-tj4m01s4	138	28	factors	factor	NNS
cord-281793-tj4m01s4	138	29	for	for	IN
cord-281793-tj4m01s4	138	30	mortality	mortality	NN
cord-281793-tj4m01s4	138	31	of	of	IN
cord-281793-tj4m01s4	138	32	adult	adult	NN
cord-281793-tj4m01s4	138	33	inpatients	inpatient	NNS
cord-281793-tj4m01s4	138	34	with	with	IN
cord-281793-tj4m01s4	138	35	COVID-19	COVID-19	NNP
cord-281793-tj4m01s4	138	36	in	in	IN
cord-281793-tj4m01s4	138	37	Wuhan	Wuhan	NNP
cord-281793-tj4m01s4	138	38	,	,	,
cord-281793-tj4m01s4	138	39	China	China	NNP
cord-281793-tj4m01s4	138	40	:	:	:
cord-281793-tj4m01s4	138	41	a	a	DT
cord-281793-tj4m01s4	138	42	retrospective	retrospective	JJ
cord-281793-tj4m01s4	138	43	cohort	cohort	NN
cord-281793-tj4m01s4	138	44	study	study	NN
cord-281793-tj4m01s4	138	45	The	the	DT
cord-281793-tj4m01s4	138	46	race	race	NN
cord-281793-tj4m01s4	138	47	is	be	VBZ
cord-281793-tj4m01s4	138	48	on	on	IN
cord-281793-tj4m01s4	138	49	for	for	IN
cord-281793-tj4m01s4	138	50	antibodies	antibody	NNS
cord-281793-tj4m01s4	138	51	that	that	WDT
cord-281793-tj4m01s4	138	52	stop	stop	VBP
cord-281793-tj4m01s4	138	53	the	the	DT
cord-281793-tj4m01s4	138	54	new	new	JJ
cord-281793-tj4m01s4	138	55	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	138	56	Antibody	antibody	NN
cord-281793-tj4m01s4	138	57	therapies	therapy	NNS
cord-281793-tj4m01s4	138	58	for	for	IN
cord-281793-tj4m01s4	138	59	the	the	DT
cord-281793-tj4m01s4	138	60	treatment	treatment	NN
cord-281793-tj4m01s4	138	61	of	of	IN
cord-281793-tj4m01s4	138	62	COVID-19	COVID-19	NNP
cord-281793-tj4m01s4	138	63	Isolation	Isolation	NNP
cord-281793-tj4m01s4	138	64	of	of	IN
cord-281793-tj4m01s4	138	65	a	a	DT
cord-281793-tj4m01s4	138	66	human	human	JJ
cord-281793-tj4m01s4	138	67	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	138	68	antibody	antibody	NN
cord-281793-tj4m01s4	138	69	specific	specific	JJ
cord-281793-tj4m01s4	138	70	for	for	IN
cord-281793-tj4m01s4	138	71	the	the	DT
cord-281793-tj4m01s4	138	72	receptor	receptor	NN
cord-281793-tj4m01s4	138	73	binding	bind	VBG
cord-281793-tj4m01s4	138	74	domain	domain	NN
cord-281793-tj4m01s4	138	75	of	of	IN
cord-281793-tj4m01s4	138	76	SARS	SARS	NNP
cord-281793-tj4m01s4	138	77	-	-	HYPH
cord-281793-tj4m01s4	138	78	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	138	79	using	use	VBG
cord-281793-tj4m01s4	138	80	a	a	DT
cord-281793-tj4m01s4	138	81	competitive	competitive	JJ
cord-281793-tj4m01s4	138	82	phage	phage	NN
cord-281793-tj4m01s4	138	83	biopanning	biopanning	NN
cord-281793-tj4m01s4	138	84	strategy	strategy	NN
cord-281793-tj4m01s4	138	85	Induction	Induction	NNP
cord-281793-tj4m01s4	138	86	of	of	IN
cord-281793-tj4m01s4	138	87	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	138	88	antibodies	antibody	NNS
cord-281793-tj4m01s4	138	89	by	by	IN
cord-281793-tj4m01s4	138	90	human	human	JJ
cord-281793-tj4m01s4	138	91	papillomavirus	papillomavirus	NN
cord-281793-tj4m01s4	138	92	vaccine	vaccine	NN
cord-281793-tj4m01s4	138	93	generated	generate	VBN
cord-281793-tj4m01s4	138	94	in	in	IN
cord-281793-tj4m01s4	138	95	mammalian	mammalian	JJ
cord-281793-tj4m01s4	138	96	cells	cell	NNS
cord-281793-tj4m01s4	138	97	Construction	construction	NN
cord-281793-tj4m01s4	138	98	and	and	CC
cord-281793-tj4m01s4	138	99	next	next	JJ
cord-281793-tj4m01s4	138	100	-	-	HYPH
cord-281793-tj4m01s4	138	101	generation	generation	NN
cord-281793-tj4m01s4	138	102	sequencing	sequencing	NN
cord-281793-tj4m01s4	138	103	analysis	analysis	NN
cord-281793-tj4m01s4	138	104	of	of	IN
cord-281793-tj4m01s4	138	105	a	a	DT
cord-281793-tj4m01s4	138	106	large	large	JJ
cord-281793-tj4m01s4	138	107	phage	phage	NN
cord-281793-tj4m01s4	138	108	-	-	HYPH
cord-281793-tj4m01s4	138	109	displayed	display	VBN
cord-281793-tj4m01s4	138	110	VNAR	VNAR	NNP
cord-281793-tj4m01s4	138	111	single	single	JJ
cord-281793-tj4m01s4	138	112	-	-	HYPH
cord-281793-tj4m01s4	138	113	domain	domain	NN
cord-281793-tj4m01s4	138	114	antibody	antibody	NN
cord-281793-tj4m01s4	138	115	library	library	NN
cord-281793-tj4m01s4	138	116	from	from	IN
cord-281793-tj4m01s4	138	117	six	six	CD
cord-281793-tj4m01s4	138	118	naive	naive	JJ
cord-281793-tj4m01s4	138	119	nurse	nurse	NN
cord-281793-tj4m01s4	138	120	sharks	shark	NNS
cord-281793-tj4m01s4	139	1	Renin	renin	NN
cord-281793-tj4m01s4	139	2	-	-	HYPH
cord-281793-tj4m01s4	139	3	angiotensin	angiotensin	NN
cord-281793-tj4m01s4	139	4	-	-	HYPH
cord-281793-tj4m01s4	139	5	aldosterone	aldosterone	NN
cord-281793-tj4m01s4	139	6	system	system	NN
cord-281793-tj4m01s4	139	7	inhibitors	inhibitor	NNS
cord-281793-tj4m01s4	139	8	in	in	IN
cord-281793-tj4m01s4	139	9	patients	patient	NNS
cord-281793-tj4m01s4	139	10	with	with	IN
cord-281793-tj4m01s4	139	11	Covid-19	Covid-19	NNP
cord-281793-tj4m01s4	139	12	Receptor	Receptor	NNP
cord-281793-tj4m01s4	139	13	recognition	recognition	NN
cord-281793-tj4m01s4	139	14	by	by	IN
cord-281793-tj4m01s4	139	15	the	the	DT
cord-281793-tj4m01s4	139	16	novel	novel	JJ
cord-281793-tj4m01s4	139	17	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	139	18	from	from	IN
cord-281793-tj4m01s4	139	19	Wuhan	Wuhan	NNP
cord-281793-tj4m01s4	139	20	:	:	:
cord-281793-tj4m01s4	139	21	an	an	DT
cord-281793-tj4m01s4	139	22	analysis	analysis	NN
cord-281793-tj4m01s4	139	23	based	base	VBN
cord-281793-tj4m01s4	139	24	on	on	IN
cord-281793-tj4m01s4	139	25	decadelong	decadelong	JJ
cord-281793-tj4m01s4	139	26	structural	structural	JJ
cord-281793-tj4m01s4	139	27	studies	study	NNS
cord-281793-tj4m01s4	139	28	of	of	IN
cord-281793-tj4m01s4	139	29	SARS	SARS	NNP
cord-281793-tj4m01s4	139	30	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	140	1	The	the	DT
cord-281793-tj4m01s4	140	2	proximal	proximal	JJ
cord-281793-tj4m01s4	140	3	origin	origin	NN
cord-281793-tj4m01s4	140	4	of	of	IN
cord-281793-tj4m01s4	140	5	SARS	SARS	NNP
cord-281793-tj4m01s4	140	6	-	-	HYPH
cord-281793-tj4m01s4	140	7	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	140	8	Cryo	Cryo	NNP
cord-281793-tj4m01s4	140	9	-	-	HYPH
cord-281793-tj4m01s4	140	10	EM	EM	NNP
cord-281793-tj4m01s4	140	11	structure	structure	NN
cord-281793-tj4m01s4	140	12	of	of	IN
cord-281793-tj4m01s4	140	13	the	the	DT
cord-281793-tj4m01s4	140	14	2019-nCoV	2019-ncov	CD
cord-281793-tj4m01s4	140	15	spike	spike	NN
cord-281793-tj4m01s4	140	16	in	in	IN
cord-281793-tj4m01s4	140	17	the	the	DT
cord-281793-tj4m01s4	140	18	prefusion	prefusion	NN
cord-281793-tj4m01s4	140	19	conformation	conformation	NN
cord-281793-tj4m01s4	140	20	Structural	structural	JJ
cord-281793-tj4m01s4	140	21	basis	basis	NN
cord-281793-tj4m01s4	140	22	for	for	IN
cord-281793-tj4m01s4	140	23	the	the	DT
cord-281793-tj4m01s4	140	24	recognition	recognition	NN
cord-281793-tj4m01s4	140	25	of	of	IN
cord-281793-tj4m01s4	140	26	SARS	SARS	NNP
cord-281793-tj4m01s4	140	27	-	-	HYPH
cord-281793-tj4m01s4	140	28	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	140	29	by	by	IN
cord-281793-tj4m01s4	140	30	full	full	JJ
cord-281793-tj4m01s4	140	31	-	-	HYPH
cord-281793-tj4m01s4	140	32	length	length	NN
cord-281793-tj4m01s4	140	33	human	human	JJ
cord-281793-tj4m01s4	140	34	ACE2	ACE2	NNP
cord-281793-tj4m01s4	140	35	Structure	Structure	NNP
cord-281793-tj4m01s4	140	36	,	,	,
cord-281793-tj4m01s4	140	37	function	function	NN
cord-281793-tj4m01s4	140	38	,	,	,
cord-281793-tj4m01s4	140	39	and	and	CC
cord-281793-tj4m01s4	140	40	antigenicity	antigenicity	NN
cord-281793-tj4m01s4	140	41	of	of	IN
cord-281793-tj4m01s4	140	42	the	the	DT
cord-281793-tj4m01s4	140	43	SARS	SARS	NNP
cord-281793-tj4m01s4	140	44	-	-	HYPH
cord-281793-tj4m01s4	140	45	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	140	46	spike	spike	NN
cord-281793-tj4m01s4	140	47	glycoprotein	glycoprotein	NN
cord-281793-tj4m01s4	140	48	Characterization	characterization	NN
cord-281793-tj4m01s4	140	49	of	of	IN
cord-281793-tj4m01s4	140	50	spike	spike	NN
cord-281793-tj4m01s4	140	51	glycoprotein	glycoprotein	NN
cord-281793-tj4m01s4	140	52	of	of	IN
cord-281793-tj4m01s4	140	53	SARS	SARS	NNP
cord-281793-tj4m01s4	140	54	-	-	HYPH
cord-281793-tj4m01s4	140	55	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	140	56	on	on	IN
cord-281793-tj4m01s4	140	57	virus	virus	NN
cord-281793-tj4m01s4	140	58	entry	entry	NN
cord-281793-tj4m01s4	140	59	and	and	CC
cord-281793-tj4m01s4	140	60	its	-PRON-	PRP$
cord-281793-tj4m01s4	140	61	immune	immune	JJ
cord-281793-tj4m01s4	140	62	cross	cross	NN
cord-281793-tj4m01s4	140	63	-	-	NN
cord-281793-tj4m01s4	140	64	reactivity	reactivity	NN
cord-281793-tj4m01s4	140	65	with	with	IN
cord-281793-tj4m01s4	140	66	SARS	SARS	NNP
cord-281793-tj4m01s4	140	67	-	-	HYPH
cord-281793-tj4m01s4	140	68	CoV	CoV	NNP
cord-281793-tj4m01s4	140	69	Human	Human	NNP
cord-281793-tj4m01s4	140	70	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	140	71	antibodies	antibody	NNS
cord-281793-tj4m01s4	140	72	elicited	elicit	VBN
cord-281793-tj4m01s4	140	73	by	by	IN
cord-281793-tj4m01s4	140	74	SARS	SARS	NNP
cord-281793-tj4m01s4	140	75	-	-	HYPH
cord-281793-tj4m01s4	140	76	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	140	77	infection	infection	NN
cord-281793-tj4m01s4	141	1	A	a	DT
cord-281793-tj4m01s4	141	2	highly	highly	RB
cord-281793-tj4m01s4	141	3	conserved	conserved	JJ
cord-281793-tj4m01s4	141	4	cryptic	cryptic	JJ
cord-281793-tj4m01s4	141	5	epitope	epitope	NN
cord-281793-tj4m01s4	141	6	in	in	IN
cord-281793-tj4m01s4	141	7	the	the	DT
cord-281793-tj4m01s4	141	8	receptor	receptor	NN
cord-281793-tj4m01s4	141	9	-	-	HYPH
cord-281793-tj4m01s4	141	10	binding	bind	VBG
cord-281793-tj4m01s4	141	11	domains	domain	NNS
cord-281793-tj4m01s4	141	12	of	of	IN
cord-281793-tj4m01s4	141	13	SARS	SARS	NNP
cord-281793-tj4m01s4	141	14	-	-	HYPH
cord-281793-tj4m01s4	141	15	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	141	16	and	and	CC
cord-281793-tj4m01s4	141	17	SARS	SARS	NNP
cord-281793-tj4m01s4	141	18	-	-	HYPH
cord-281793-tj4m01s4	141	19	CoV	CoV	NNP
cord-281793-tj4m01s4	141	20	A	a	DT
cord-281793-tj4m01s4	141	21	human	human	JJ
cord-281793-tj4m01s4	141	22	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	141	23	antibody	antibody	NN
cord-281793-tj4m01s4	141	24	blocking	block	VBG
cord-281793-tj4m01s4	141	25	SARS	SARS	NNP
cord-281793-tj4m01s4	141	26	-	-	HYPH
cord-281793-tj4m01s4	141	27	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	141	28	infection	infection	NN
cord-281793-tj4m01s4	141	29	Structural	structural	JJ
cord-281793-tj4m01s4	141	30	and	and	CC
cord-281793-tj4m01s4	141	31	functional	functional	JJ
cord-281793-tj4m01s4	141	32	analysis	analysis	NN
cord-281793-tj4m01s4	141	33	of	of	IN
cord-281793-tj4m01s4	141	34	a	a	DT
cord-281793-tj4m01s4	141	35	potent	potent	JJ
cord-281793-tj4m01s4	141	36	sarbecovirus	sarbecovirus	JJ
cord-281793-tj4m01s4	141	37	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	141	38	antibody	antibody	NN
cord-281793-tj4m01s4	141	39	Structural	structural	JJ
cord-281793-tj4m01s4	141	40	basis	basis	NN
cord-281793-tj4m01s4	141	41	for	for	IN
cord-281793-tj4m01s4	141	42	potent	potent	JJ
cord-281793-tj4m01s4	141	43	neutralization	neutralization	NN
cord-281793-tj4m01s4	141	44	of	of	IN
cord-281793-tj4m01s4	141	45	Betacoronaviruses	Betacoronaviruses	NNP
cord-281793-tj4m01s4	141	46	by	by	IN
cord-281793-tj4m01s4	141	47	single	single	JJ
cord-281793-tj4m01s4	141	48	-	-	HYPH
cord-281793-tj4m01s4	141	49	domain	domain	NN
cord-281793-tj4m01s4	141	50	Camelid	Camelid	NNP
cord-281793-tj4m01s4	141	51	antibodies	antibody	NNS
cord-281793-tj4m01s4	141	52	Crystal	Crystal	NNP
cord-281793-tj4m01s4	141	53	structure	structure	NN
cord-281793-tj4m01s4	141	54	of	of	IN
cord-281793-tj4m01s4	141	55	a	a	DT
cord-281793-tj4m01s4	141	56	shark	shark	NN
cord-281793-tj4m01s4	141	57	single	single	JJ
cord-281793-tj4m01s4	141	58	-	-	HYPH
cord-281793-tj4m01s4	141	59	domain	domain	NN
cord-281793-tj4m01s4	141	60	antibody	antibody	NN
cord-281793-tj4m01s4	141	61	V	v	NN
cord-281793-tj4m01s4	141	62	region	region	NN
cord-281793-tj4m01s4	141	63	in	in	IN
cord-281793-tj4m01s4	141	64	complex	complex	NN
cord-281793-tj4m01s4	141	65	with	with	IN
cord-281793-tj4m01s4	141	66	lysozyme	lysozyme	NNS
cord-281793-tj4m01s4	141	67	A	a	DT
cord-281793-tj4m01s4	141	68	cold	cold	JJ
cord-281793-tj4m01s4	141	69	-	-	HYPH
cord-281793-tj4m01s4	141	70	blooded	blooded	JJ
cord-281793-tj4m01s4	141	71	view	view	NN
cord-281793-tj4m01s4	141	72	of	of	IN
cord-281793-tj4m01s4	141	73	adaptive	adaptive	JJ
cord-281793-tj4m01s4	141	74	immunity	immunity	NN
cord-281793-tj4m01s4	141	75	Ancient	Ancient	NNP
cord-281793-tj4m01s4	141	76	species	specie	NNS
cord-281793-tj4m01s4	141	77	offers	offer	VBZ
cord-281793-tj4m01s4	141	78	contemporary	contemporary	JJ
cord-281793-tj4m01s4	141	79	therapeutics	therapeutic	NNS
cord-281793-tj4m01s4	141	80	:	:	:
cord-281793-tj4m01s4	141	81	an	an	DT
cord-281793-tj4m01s4	141	82	update	update	NN
cord-281793-tj4m01s4	141	83	on	on	IN
cord-281793-tj4m01s4	141	84	shark	shark	NN
cord-281793-tj4m01s4	141	85	VNAR	VNAR	NNP
cord-281793-tj4m01s4	141	86	single	single	JJ
cord-281793-tj4m01s4	141	87	domain	domain	NN
cord-281793-tj4m01s4	141	88	antibody	antibody	NN
cord-281793-tj4m01s4	141	89	sequences	sequence	NNS
cord-281793-tj4m01s4	141	90	,	,	,
cord-281793-tj4m01s4	141	91	phage	phage	NN
cord-281793-tj4m01s4	141	92	libraries	library	NNS
cord-281793-tj4m01s4	141	93	and	and	CC
cord-281793-tj4m01s4	141	94	potential	potential	JJ
cord-281793-tj4m01s4	141	95	clinical	clinical	JJ
cord-281793-tj4m01s4	141	96	applications	application	NNS
cord-281793-tj4m01s4	142	1	General	general	JJ
cord-281793-tj4m01s4	142	2	strategy	strategy	NN
cord-281793-tj4m01s4	142	3	to	to	TO
cord-281793-tj4m01s4	142	4	humanize	humanize	VB
cord-281793-tj4m01s4	142	5	a	a	DT
cord-281793-tj4m01s4	142	6	Camelid	Camelid	NNP
cord-281793-tj4m01s4	142	7	single	single	JJ
cord-281793-tj4m01s4	142	8	-	-	HYPH
cord-281793-tj4m01s4	142	9	domain	domain	NN
cord-281793-tj4m01s4	142	10	antibody	antibody	NN
cord-281793-tj4m01s4	142	11	and	and	CC
cord-281793-tj4m01s4	142	12	identification	identification	NN
cord-281793-tj4m01s4	142	13	of	of	IN
cord-281793-tj4m01s4	142	14	a	a	DT
cord-281793-tj4m01s4	142	15	universal	universal	JJ
cord-281793-tj4m01s4	142	16	humanized	humanize	VBN
cord-281793-tj4m01s4	142	17	nanobody	nanobody	NN
cord-281793-tj4m01s4	142	18	scaffold	scaffold	NN
cord-281793-tj4m01s4	142	19	Phylogenetic	Phylogenetic	NNP
cord-281793-tj4m01s4	142	20	network	network	NN
cord-281793-tj4m01s4	142	21	analysis	analysis	NN
cord-281793-tj4m01s4	142	22	of	of	IN
cord-281793-tj4m01s4	142	23	SARS	SARS	NNP
cord-281793-tj4m01s4	142	24	-	-	HYPH
cord-281793-tj4m01s4	142	25	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	142	26	genomes	genome	NNS
cord-281793-tj4m01s4	142	27	Patient	patient	NN
cord-281793-tj4m01s4	142	28	-	-	HYPH
cord-281793-tj4m01s4	142	29	derived	derive	VBN
cord-281793-tj4m01s4	142	30	mutations	mutation	NNS
cord-281793-tj4m01s4	142	31	impact	impact	NN
cord-281793-tj4m01s4	142	32	pathogenicity	pathogenicity	NN
cord-281793-tj4m01s4	142	33	of	of	IN
cord-281793-tj4m01s4	142	34	SARS	SARS	NNP
cord-281793-tj4m01s4	142	35	-	-	HYPH
cord-281793-tj4m01s4	142	36	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	142	37	Spike	Spike	NNP
cord-281793-tj4m01s4	142	38	mutation	mutation	NN
cord-281793-tj4m01s4	142	39	pipeline	pipeline	NN
cord-281793-tj4m01s4	142	40	reveals	reveal	VBZ
cord-281793-tj4m01s4	142	41	the	the	DT
cord-281793-tj4m01s4	142	42	emergence	emergence	NN
cord-281793-tj4m01s4	142	43	of	of	IN
cord-281793-tj4m01s4	142	44	a	a	DT
cord-281793-tj4m01s4	142	45	more	more	RBR
cord-281793-tj4m01s4	142	46	transmissible	transmissible	JJ
cord-281793-tj4m01s4	142	47	form	form	NN
cord-281793-tj4m01s4	142	48	of	of	IN
cord-281793-tj4m01s4	142	49	SARS	SARS	NNP
cord-281793-tj4m01s4	142	50	-	-	HYPH
cord-281793-tj4m01s4	142	51	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	142	52	A	a	DT
cord-281793-tj4m01s4	142	53	potent	potent	JJ
cord-281793-tj4m01s4	142	54	neutralizing	neutralize	VBG
cord-281793-tj4m01s4	142	55	human	human	JJ
cord-281793-tj4m01s4	142	56	antibody	antibody	NN
cord-281793-tj4m01s4	142	57	reveals	reveal	VBZ
cord-281793-tj4m01s4	142	58	the	the	DT
cord-281793-tj4m01s4	142	59	N	n	CD
cord-281793-tj4m01s4	142	60	-	-	HYPH
cord-281793-tj4m01s4	142	61	terminal	terminal	NN
cord-281793-tj4m01s4	142	62	domain	domain	NN
cord-281793-tj4m01s4	142	63	of	of	IN
cord-281793-tj4m01s4	142	64	the	the	DT
cord-281793-tj4m01s4	142	65	Spike	Spike	NNP
cord-281793-tj4m01s4	142	66	protein	protein	NN
cord-281793-tj4m01s4	142	67	of	of	IN
cord-281793-tj4m01s4	142	68	SARS	SARS	NNP
cord-281793-tj4m01s4	142	69	-	-	HYPH
cord-281793-tj4m01s4	142	70	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	142	71	as	as	IN
cord-281793-tj4m01s4	142	72	a	a	DT
cord-281793-tj4m01s4	142	73	site	site	NN
cord-281793-tj4m01s4	142	74	of	of	IN
cord-281793-tj4m01s4	142	75	vulnerability	vulnerability	NN
cord-281793-tj4m01s4	142	76	Monoclonal	Monoclonal	NNP
cord-281793-tj4m01s4	142	77	antibodies	antibody	NNS
cord-281793-tj4m01s4	142	78	targeting	target	VBG
cord-281793-tj4m01s4	142	79	the	the	DT
cord-281793-tj4m01s4	142	80	HR2	HR2	NNP
cord-281793-tj4m01s4	142	81	domain	domain	NN
cord-281793-tj4m01s4	142	82	and	and	CC
cord-281793-tj4m01s4	142	83	the	the	DT
cord-281793-tj4m01s4	142	84	region	region	NN
cord-281793-tj4m01s4	142	85	immediately	immediately	RB
cord-281793-tj4m01s4	142	86	upstream	upstream	RB
cord-281793-tj4m01s4	142	87	of	of	IN
cord-281793-tj4m01s4	142	88	the	the	DT
cord-281793-tj4m01s4	142	89	HR2	hr2	NN
cord-281793-tj4m01s4	142	90	of	of	IN
cord-281793-tj4m01s4	142	91	the	the	DT
cord-281793-tj4m01s4	142	92	S	S	NNP
cord-281793-tj4m01s4	142	93	protein	protein	NN
cord-281793-tj4m01s4	142	94	neutralize	neutralize	VB
cord-281793-tj4m01s4	142	95	in	in	IN
cord-281793-tj4m01s4	142	96	vitro	vitro	FW
cord-281793-tj4m01s4	142	97	infection	infection	NN
cord-281793-tj4m01s4	142	98	of	of	IN
cord-281793-tj4m01s4	142	99	severe	severe	JJ
cord-281793-tj4m01s4	142	100	acute	acute	JJ
cord-281793-tj4m01s4	142	101	respiratory	respiratory	JJ
cord-281793-tj4m01s4	142	102	syndrome	syndrome	NN
cord-281793-tj4m01s4	142	103	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	142	104	Inhibition	Inhibition	NNP
cord-281793-tj4m01s4	142	105	of	of	IN
cord-281793-tj4m01s4	142	106	SARS	SARS	NNP
cord-281793-tj4m01s4	142	107	-	-	HYPH
cord-281793-tj4m01s4	142	108	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	142	109	(	(	-LRB-
cord-281793-tj4m01s4	142	110	previously	previously	RB
cord-281793-tj4m01s4	142	111	2019-nCoV	2019-ncov	CD
cord-281793-tj4m01s4	142	112	)	)	-RRB-
cord-281793-tj4m01s4	142	113	infection	infection	NN
cord-281793-tj4m01s4	142	114	by	by	IN
cord-281793-tj4m01s4	142	115	a	a	DT
cord-281793-tj4m01s4	142	116	highly	highly	RB
cord-281793-tj4m01s4	142	117	potent	potent	JJ
cord-281793-tj4m01s4	142	118	pan	pan	JJ
cord-281793-tj4m01s4	142	119	-	-	JJ
cord-281793-tj4m01s4	142	120	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	142	121	fusion	fusion	NN
cord-281793-tj4m01s4	142	122	inhibitor	inhibitor	NN
cord-281793-tj4m01s4	142	123	targeting	target	VBG
cord-281793-tj4m01s4	142	124	its	-PRON-	PRP$
cord-281793-tj4m01s4	142	125	spike	spike	NN
cord-281793-tj4m01s4	142	126	protein	protein	NN
cord-281793-tj4m01s4	142	127	that	that	WDT
cord-281793-tj4m01s4	142	128	harbors	harbor	VBZ
cord-281793-tj4m01s4	142	129	a	a	DT
cord-281793-tj4m01s4	142	130	high	high	JJ
cord-281793-tj4m01s4	142	131	capacity	capacity	NN
cord-281793-tj4m01s4	142	132	to	to	TO
cord-281793-tj4m01s4	142	133	mediate	mediate	VB
cord-281793-tj4m01s4	142	134	membrane	membrane	NN
cord-281793-tj4m01s4	142	135	fusion	fusion	NN
cord-281793-tj4m01s4	142	136	Therapeutic	therapeutic	JJ
cord-281793-tj4m01s4	142	137	strategies	strategy	NNS
cord-281793-tj4m01s4	142	138	in	in	IN
cord-281793-tj4m01s4	142	139	an	an	DT
cord-281793-tj4m01s4	142	140	outbreak	outbreak	NN
cord-281793-tj4m01s4	142	141	scenario	scenario	NN
cord-281793-tj4m01s4	142	142	to	to	TO
cord-281793-tj4m01s4	142	143	treat	treat	VB
cord-281793-tj4m01s4	142	144	the	the	DT
cord-281793-tj4m01s4	142	145	novel	novel	JJ
cord-281793-tj4m01s4	142	146	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	142	147	originating	originate	VBG
cord-281793-tj4m01s4	142	148	in	in	IN
cord-281793-tj4m01s4	142	149	Wuhan	Wuhan	NNP
cord-281793-tj4m01s4	142	150	Neutralization	Neutralization	NNP
cord-281793-tj4m01s4	142	151	of	of	IN
cord-281793-tj4m01s4	142	152	SARS	SARS	NNP
cord-281793-tj4m01s4	142	153	-	-	HYPH
cord-281793-tj4m01s4	142	154	CoV-2	CoV-2	NNP
cord-281793-tj4m01s4	142	155	spike	spike	NN
cord-281793-tj4m01s4	142	156	pseudotyped	pseudotype	VBD
cord-281793-tj4m01s4	142	157	virus	virus	NN
cord-281793-tj4m01s4	142	158	by	by	IN
cord-281793-tj4m01s4	142	159	recombinant	recombinant	JJ
cord-281793-tj4m01s4	142	160	ACE2-Ig	ACE2-Ig	NNP
cord-281793-tj4m01s4	142	161	Inhibition	Inhibition	NNP
cord-281793-tj4m01s4	142	162	of	of	IN
cord-281793-tj4m01s4	142	163	SARS	SARS	NNP
cord-281793-tj4m01s4	142	164	pseudovirus	pseudovirus	NNP
cord-281793-tj4m01s4	142	165	cell	cell	NN
cord-281793-tj4m01s4	142	166	entry	entry	NN
cord-281793-tj4m01s4	142	167	by	by	IN
cord-281793-tj4m01s4	142	168	lactoferrin	lactoferrin	NN
cord-281793-tj4m01s4	142	169	binding	bind	VBG
cord-281793-tj4m01s4	142	170	to	to	IN
cord-281793-tj4m01s4	142	171	heparan	heparan	JJ
cord-281793-tj4m01s4	142	172	sulfate	sulfate	NN
cord-281793-tj4m01s4	142	173	proteoglycans	proteoglycan	NNS
cord-281793-tj4m01s4	142	174	Glypicans	Glypicans	NNP
cord-281793-tj4m01s4	142	175	as	as	IN
cord-281793-tj4m01s4	142	176	cancer	cancer	NN
cord-281793-tj4m01s4	142	177	therapeutic	therapeutic	JJ
cord-281793-tj4m01s4	142	178	targets	target	NNS
cord-281793-tj4m01s4	142	179	Isolation	isolation	NN
cord-281793-tj4m01s4	142	180	of	of	IN
cord-281793-tj4m01s4	142	181	antibodies	antibody	NNS
cord-281793-tj4m01s4	142	182	to	to	IN
cord-281793-tj4m01s4	142	183	Heparan	Heparan	NNP
cord-281793-tj4m01s4	142	184	Sulfate	Sulfate	NNP
cord-281793-tj4m01s4	142	185	on	on	IN
cord-281793-tj4m01s4	142	186	Glypicans	Glypicans	NNPS
cord-281793-tj4m01s4	142	187	by	by	IN
cord-281793-tj4m01s4	142	188	phage	phage	NN
cord-281793-tj4m01s4	142	189	display	display	NN
cord-281793-tj4m01s4	142	190	Human	human	JJ
cord-281793-tj4m01s4	142	191	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	142	192	antibody	antibody	NN
cord-281793-tj4m01s4	142	193	targeting	target	VBG
cord-281793-tj4m01s4	142	194	the	the	DT
cord-281793-tj4m01s4	142	195	heparan	heparan	NN
cord-281793-tj4m01s4	142	196	sulfate	sulfate	NN
cord-281793-tj4m01s4	142	197	chains	chain	NNS
cord-281793-tj4m01s4	142	198	of	of	IN
cord-281793-tj4m01s4	142	199	Glypican-3	Glypican-3	NNP
cord-281793-tj4m01s4	142	200	inhibits	inhibit	VBZ
cord-281793-tj4m01s4	142	201	HGF	hgf	NN
cord-281793-tj4m01s4	142	202	-	-	HYPH
cord-281793-tj4m01s4	142	203	mediated	mediate	VBN
cord-281793-tj4m01s4	142	204	migration	migration	NN
cord-281793-tj4m01s4	142	205	and	and	CC
cord-281793-tj4m01s4	142	206	motility	motility	NN
cord-281793-tj4m01s4	142	207	of	of	IN
cord-281793-tj4m01s4	142	208	hepatocellular	hepatocellular	JJ
cord-281793-tj4m01s4	142	209	carcinoma	carcinoma	NN
cord-281793-tj4m01s4	142	210	cells	cell	NNS
cord-281793-tj4m01s4	142	211	Epitope	Epitope	NNP
cord-281793-tj4m01s4	142	212	mapping	mapping	NN
cord-281793-tj4m01s4	142	213	by	by	IN
cord-281793-tj4m01s4	142	214	a	a	DT
cord-281793-tj4m01s4	142	215	Wnt	Wnt	NNP
cord-281793-tj4m01s4	142	216	-	-	HYPH
cord-281793-tj4m01s4	142	217	blocking	block	VBG
cord-281793-tj4m01s4	142	218	antibody	antibody	NN
cord-281793-tj4m01s4	142	219	:	:	:
cord-281793-tj4m01s4	142	220	evidence	evidence	NN
cord-281793-tj4m01s4	142	221	of	of	IN
cord-281793-tj4m01s4	142	222	the	the	DT
cord-281793-tj4m01s4	142	223	Wnt	Wnt	NNP
cord-281793-tj4m01s4	142	224	binding	bind	VBG
cord-281793-tj4m01s4	142	225	domain	domain	NN
cord-281793-tj4m01s4	142	226	in	in	IN
cord-281793-tj4m01s4	142	227	heparan	heparan	NN
cord-281793-tj4m01s4	142	228	sulfate	sulfate	NN
cord-281793-tj4m01s4	142	229	Infectious	infectious	JJ
cord-281793-tj4m01s4	142	230	entry	entry	NN
cord-281793-tj4m01s4	142	231	and	and	CC
cord-281793-tj4m01s4	142	232	neutralization	neutralization	NN
cord-281793-tj4m01s4	142	233	of	of	IN
cord-281793-tj4m01s4	142	234	pathogenic	pathogenic	JJ
cord-281793-tj4m01s4	142	235	JC	JC	NNP
cord-281793-tj4m01s4	142	236	polyomaviruses	polyomaviruse	VBZ
cord-281793-tj4m01s4	142	237	Human	human	JJ
cord-281793-tj4m01s4	142	238	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	142	239	antibody	antibody	NN
cord-281793-tj4m01s4	142	240	combination	combination	NN
cord-281793-tj4m01s4	142	241	against	against	IN
cord-281793-tj4m01s4	142	242	SARS	SARS	NNP
cord-281793-tj4m01s4	142	243	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	142	244	:	:	:
cord-281793-tj4m01s4	142	245	synergy	synergy	NN
cord-281793-tj4m01s4	142	246	and	and	CC
cord-281793-tj4m01s4	142	247	coverage	coverage	NN
cord-281793-tj4m01s4	142	248	of	of	IN
cord-281793-tj4m01s4	142	249	escape	escape	NN
cord-281793-tj4m01s4	142	250	mutants	mutant	NNS
cord-281793-tj4m01s4	142	251	Towards	towards	IN
cord-281793-tj4m01s4	142	252	a	a	DT
cord-281793-tj4m01s4	142	253	solution	solution	NN
cord-281793-tj4m01s4	142	254	to	to	IN
cord-281793-tj4m01s4	142	255	MERS	MERS	NNP
cord-281793-tj4m01s4	142	256	:	:	:
cord-281793-tj4m01s4	142	257	protective	protective	JJ
cord-281793-tj4m01s4	142	258	human	human	JJ
cord-281793-tj4m01s4	142	259	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	142	260	antibodies	antibody	NNS
cord-281793-tj4m01s4	142	261	targeting	target	VBG
cord-281793-tj4m01s4	142	262	different	different	JJ
cord-281793-tj4m01s4	142	263	domains	domain	NNS
cord-281793-tj4m01s4	142	264	and	and	CC
cord-281793-tj4m01s4	142	265	functions	function	NNS
cord-281793-tj4m01s4	142	266	of	of	IN
cord-281793-tj4m01s4	142	267	the	the	DT
cord-281793-tj4m01s4	142	268	MERS	MERS	NNP
cord-281793-tj4m01s4	142	269	-	-	HYPH
cord-281793-tj4m01s4	142	270	coronavirus	coronavirus	NN
cord-281793-tj4m01s4	142	271	spike	spike	NN
cord-281793-tj4m01s4	142	272	glycoprotein	glycoprotein	NN
cord-281793-tj4m01s4	142	273	antibodies	antibody	NNS
cord-281793-tj4m01s4	142	274	(	(	-LRB-
cord-281793-tj4m01s4	142	275	including	include	VBG
cord-281793-tj4m01s4	142	276	multiple	multiple	JJ
cord-281793-tj4m01s4	142	277	single	single	JJ
cord-281793-tj4m01s4	142	278	domain	domain	NN
cord-281793-tj4m01s4	142	279	antibodies	antibody	NNS
cord-281793-tj4m01s4	142	280	)	)	-RRB-
cord-281793-tj4m01s4	142	281	that	that	WDT
cord-281793-tj4m01s4	142	282	target	target	VBP
cord-281793-tj4m01s4	142	283	different	different	JJ
cord-281793-tj4m01s4	142	284	epitopes	epitope	NNS
cord-281793-tj4m01s4	142	285	via	via	IN
cord-281793-tj4m01s4	142	286	different	different	JJ
cord-281793-tj4m01s4	142	287	mechanisms	mechanism	NNS
cord-281793-tj4m01s4	142	288	.	.	.
cord-281793-tj4m01s4	143	1	I	-PRON-	PRP
cord-281793-tj4m01s4	143	2	would	would	MD
cord-281793-tj4m01s4	143	3	like	like	VB
cord-281793-tj4m01s4	143	4	to	to	TO
cord-281793-tj4m01s4	143	5	thank	thank	VB
cord-281793-tj4m01s4	143	6	Chin	Chin	NNP
cord-281793-tj4m01s4	143	7	-	-	HYPH
cord-281793-tj4m01s4	143	8	Hsien	Hsien	NNP
cord-281793-tj4m01s4	143	9	Tai	Tai	NNP
cord-281793-tj4m01s4	143	10	,	,	,
cord-281793-tj4m01s4	143	11	Yaping	Yaping	NNP
cord-281793-tj4m01s4	143	12	Sun	Sun	NNP
cord-281793-tj4m01s4	143	13	,	,	,
cord-281793-tj4m01s4	143	14	Bryan	Bryan	NNP
cord-281793-tj4m01s4	143	15	Fleming	Fleming	NNP
cord-281793-tj4m01s4	143	16	,	,	,
cord-281793-tj4m01s4	143	17	and	and	CC
cord-281793-tj4m01s4	143	18	Jessica	Jessica	NNP
cord-281793-tj4m01s4	143	19	Hong	Hong	NNP
cord-281793-tj4m01s4	143	20	(	(	-LRB-
cord-281793-tj4m01s4	143	21	NCI	NCI	NNP
cord-281793-tj4m01s4	143	22	)	)	-RRB-
cord-281793-tj4m01s4	143	23	for	for	IN
cord-281793-tj4m01s4	143	24	reading	read	VBG
cord-281793-tj4m01s4	143	25	the	the	DT
cord-281793-tj4m01s4	143	26	manuscript	manuscript	NN
cord-281793-tj4m01s4	143	27	,	,	,
cord-281793-tj4m01s4	143	28	and	and	CC
cord-281793-tj4m01s4	143	29	Alan	Alan	NNP
cord-281793-tj4m01s4	143	30	Hoofring	Hoofring	NNP
cord-281793-tj4m01s4	143	31	and	and	CC
cord-281793-tj4m01s4	143	32	Ethan	Ethan	NNP
cord-281793-tj4m01s4	143	33	Tyler	Tyler	NNP
cord-281793-tj4m01s4	144	1	(	(	-LRB-
cord-281793-tj4m01s4	144	2	NIH	NIH	NNP
cord-281793-tj4m01s4	144	3	Medical	Medical	NNP
cord-281793-tj4m01s4	144	4	Arts	Arts	NNP
cord-281793-tj4m01s4	144	5	Design	Design	NNP
cord-281793-tj4m01s4	144	6	Section	Section	NNP
cord-281793-tj4m01s4	144	7	)	)	-RRB-
cord-281793-tj4m01s4	144	8	for	for	IN
cord-281793-tj4m01s4	144	9	making	make	VBG
cord-281793-tj4m01s4	144	10	the	the	DT
cord-281793-tj4m01s4	144	11	figure	figure	NN
cord-281793-tj4m01s4	144	12	.	.	.
cord-281793-tj4m01s4	145	1	The	the	DT
cord-281793-tj4m01s4	145	2	content	content	NN
cord-281793-tj4m01s4	145	3	of	of	IN
cord-281793-tj4m01s4	145	4	this	this	DT
cord-281793-tj4m01s4	145	5	publication	publication	NN
cord-281793-tj4m01s4	145	6	does	do	VBZ
cord-281793-tj4m01s4	145	7	not	not	RB
cord-281793-tj4m01s4	145	8	necessarily	necessarily	RB
cord-281793-tj4m01s4	145	9	reflect	reflect	VB
cord-281793-tj4m01s4	145	10	the	the	DT
cord-281793-tj4m01s4	145	11	views	view	NNS
cord-281793-tj4m01s4	145	12	or	or	CC
cord-281793-tj4m01s4	145	13	policies	policy	NNS
cord-281793-tj4m01s4	145	14	of	of	IN
cord-281793-tj4m01s4	145	15	the	the	DT
cord-281793-tj4m01s4	145	16	Department	Department	NNP
cord-281793-tj4m01s4	145	17	of	of	IN
cord-281793-tj4m01s4	145	18	Health	Health	NNP
cord-281793-tj4m01s4	145	19	and	and	CC
cord-281793-tj4m01s4	145	20	Human	Human	NNP
cord-281793-tj4m01s4	145	21	Services	Services	NNPS
cord-281793-tj4m01s4	145	22	nor	nor	CC
cord-281793-tj4m01s4	145	23	does	do	VBZ
cord-281793-tj4m01s4	145	24	mention	mention	VB
cord-281793-tj4m01s4	145	25	of	of	IN
cord-281793-tj4m01s4	145	26	trade	trade	NN
cord-281793-tj4m01s4	145	27	names	name	NNS
cord-281793-tj4m01s4	145	28	,	,	,
cord-281793-tj4m01s4	145	29	commercial	commercial	JJ
cord-281793-tj4m01s4	145	30	products	product	NNS
cord-281793-tj4m01s4	145	31	,	,	,
cord-281793-tj4m01s4	145	32	or	or	CC
cord-281793-tj4m01s4	145	33	organizations	organization	NNS
cord-281793-tj4m01s4	145	34	imply	imply	VBP
cord-281793-tj4m01s4	145	35	endorsement	endorsement	NN
cord-281793-tj4m01s4	145	36	by	by	IN
cord-281793-tj4m01s4	145	37	the	the	DT
cord-281793-tj4m01s4	145	38	U.S.	U.S.	NNP
cord-281793-tj4m01s4	145	39	Government	Government	NNP
cord-281793-tj4m01s4	145	40	.	.	.
cord-281793-tj4m01s4	146	1	The	the	DT
cord-281793-tj4m01s4	146	2	HS20	HS20	NNP
cord-281793-tj4m01s4	146	3	human	human	JJ
cord-281793-tj4m01s4	146	4	monoclonal	monoclonal	JJ
cord-281793-tj4m01s4	146	5	antibody	antibody	NN
cord-281793-tj4m01s4	146	6	is	be	VBZ
cord-281793-tj4m01s4	146	7	available	available	JJ
cord-281793-tj4m01s4	146	8	for	for	IN
cord-281793-tj4m01s4	146	9	licensing	licensing	NN
cord-281793-tj4m01s4	146	10	,	,	,
cord-281793-tj4m01s4	146	11	in	in	IN
cord-281793-tj4m01s4	146	12	a	a	DT
cord-281793-tj4m01s4	146	13	wide	wide	JJ
cord-281793-tj4m01s4	146	14	range	range	NN
cord-281793-tj4m01s4	146	15	of	of	IN
cord-281793-tj4m01s4	146	16	fields	field	NNS
cord-281793-tj4m01s4	146	17	of	of	IN
cord-281793-tj4m01s4	146	18	use	use	NN
cord-281793-tj4m01s4	146	19	,	,	,
cord-281793-tj4m01s4	146	20	from	from	IN
cord-281793-tj4m01s4	146	21	the	the	DT
cord-281793-tj4m01s4	146	22	National	National	NNP
cord-281793-tj4m01s4	146	23	Cancer	Cancer	NNP
cord-281793-tj4m01s4	146	24	Institute	Institute	NNP
cord-281793-tj4m01s4	146	25	.	.	.
cord-281793-tj4m01s4	147	1	If	if	IN
cord-281793-tj4m01s4	147	2	you	-PRON-	PRP
cord-281793-tj4m01s4	147	3	are	be	VBP
cord-281793-tj4m01s4	147	4	interested	interested	JJ
cord-281793-tj4m01s4	147	5	in	in	IN
cord-281793-tj4m01s4	147	6	obtaining	obtain	VBG
cord-281793-tj4m01s4	147	7	a	a	DT
cord-281793-tj4m01s4	147	8	license	license	NN
cord-281793-tj4m01s4	147	9	,	,	,
cord-281793-tj4m01s4	147	10	please	please	UH
cord-281793-tj4m01s4	147	11	contact	contact	VB
cord-281793-tj4m01s4	147	12	Dr.	Dr.	NNP
cord-281793-tj4m01s4	147	13	Mitchell	Mitchell	NNP
cord-281793-tj4m01s4	147	14	Ho	Ho	NNP
cord-281793-tj4m01s4	147	15	.	.	.
cord-281793-tj4m01s4	148	1	The	the	DT
cord-281793-tj4m01s4	148	2	author	author	NN
cord-281793-tj4m01s4	148	3	is	be	VBZ
cord-281793-tj4m01s4	148	4	supported	support	VBN
cord-281793-tj4m01s4	148	5	by	by	IN
cord-281793-tj4m01s4	148	6	the	the	DT
cord-281793-tj4m01s4	148	7	Intramural	Intramural	NNP
cord-281793-tj4m01s4	148	8	Research	Research	NNP
cord-281793-tj4m01s4	148	9	Program	Program	NNP
cord-281793-tj4m01s4	148	10	of	of	IN
cord-281793-tj4m01s4	148	11	NIH	NIH	NNP
cord-281793-tj4m01s4	148	12	,	,	,
cord-281793-tj4m01s4	148	13	NCI	NCI	NNP
cord-281793-tj4m01s4	148	14	(	(	-LRB-
cord-281793-tj4m01s4	148	15	Z01	Z01	NNP
cord-281793-tj4m01s4	148	16	BC010891	BC010891	NNP
cord-281793-tj4m01s4	148	17	,	,	,
cord-281793-tj4m01s4	148	18	ZIA	ZIA	NNP
cord-281793-tj4m01s4	148	19	BC010891	BC010891	NNP
cord-281793-tj4m01s4	148	20	,	,	,
cord-281793-tj4m01s4	148	21	and	and	CC
cord-281793-tj4m01s4	148	22	NCI	NCI	NNP
cord-281793-tj4m01s4	148	23	CCR	CCR	NNP
cord-281793-tj4m01s4	148	24	Antibody	Antibody	NNP
cord-281793-tj4m01s4	148	25	Engineering	Engineering	NNP
cord-281793-tj4m01s4	148	26	Program	Program	NNP
cord-281793-tj4m01s4	148	27	)	)	-RRB-
cord-281793-tj4m01s4	148	28	.	.	.
cord-281793-tj4m01s4	149	1	None	none	NN
cord-281793-tj4m01s4	149	2	declared	declare	VBD
cord-281793-tj4m01s4	149	3	.	.	.