id sid tid token lemma pos cord-286950-j7m69833 1 1 key key NN cord-286950-j7m69833 1 2 : : : cord-286950-j7m69833 1 3 cord-286950-j7m69833 cord-286950-j7m69833 NNP cord-286950-j7m69833 1 4 authors author NNS cord-286950-j7m69833 1 5 : : : cord-286950-j7m69833 1 6 Imperiale Imperiale NNP cord-286950-j7m69833 1 7 , , , cord-286950-j7m69833 1 8 Michael Michael NNP cord-286950-j7m69833 1 9 J. J. NNP cord-286950-j7m69833 1 10 ; ; : cord-286950-j7m69833 1 11 Howard Howard NNP cord-286950-j7m69833 1 12 , , , cord-286950-j7m69833 1 13 Don Don NNP cord-286950-j7m69833 1 14 ; ; : cord-286950-j7m69833 1 15 Casadevall Casadevall NNP cord-286950-j7m69833 1 16 , , , cord-286950-j7m69833 2 1 Arturo Arturo NNP cord-286950-j7m69833 2 2 title title NN cord-286950-j7m69833 2 3 : : : cord-286950-j7m69833 2 4 The the DT cord-286950-j7m69833 2 5 Silver Silver NNP cord-286950-j7m69833 2 6 Lining lining NN cord-286950-j7m69833 2 7 in in IN cord-286950-j7m69833 2 8 Gain gain NN cord-286950-j7m69833 2 9 - - HYPH cord-286950-j7m69833 2 10 of of IN cord-286950-j7m69833 2 11 - - HYPH cord-286950-j7m69833 2 12 Function function NN cord-286950-j7m69833 2 13 Experiments experiment NNS cord-286950-j7m69833 2 14 with with IN cord-286950-j7m69833 2 15 Pathogens pathogen NNS cord-286950-j7m69833 2 16 of of IN cord-286950-j7m69833 2 17 Pandemic Pandemic NNP cord-286950-j7m69833 2 18 Potential potential JJ cord-286950-j7m69833 2 19 date date NN cord-286950-j7m69833 2 20 : : : cord-286950-j7m69833 2 21 2018 2018 CD cord-286950-j7m69833 2 22 - - HYPH cord-286950-j7m69833 2 23 08 08 CD cord-286950-j7m69833 2 24 - - HYPH cord-286950-j7m69833 2 25 28 28 CD cord-286950-j7m69833 2 26 journal journal NN cord-286950-j7m69833 2 27 : : : cord-286950-j7m69833 3 1 Influenza Influenza NNP cord-286950-j7m69833 3 2 Virus Virus NNP cord-286950-j7m69833 3 3 DOI doi NN cord-286950-j7m69833 3 4 : : : cord-286950-j7m69833 3 5 10.1007/978 10.1007/978 CD cord-286950-j7m69833 3 6 - - HYPH cord-286950-j7m69833 3 7 1 1 CD cord-286950-j7m69833 3 8 - - HYPH cord-286950-j7m69833 3 9 4939 4939 CD cord-286950-j7m69833 3 10 - - HYPH cord-286950-j7m69833 3 11 8678 8678 CD cord-286950-j7m69833 3 12 - - HYPH cord-286950-j7m69833 3 13 1_28 1_28 CD cord-286950-j7m69833 3 14 sha sha NN cord-286950-j7m69833 3 15 : : : cord-286950-j7m69833 4 1 83215814219b9cd6f2f5a6e7bca32e5b7599c138 83215814219b9cd6f2f5a6e7bca32e5b7599c138 CD cord-286950-j7m69833 4 2 doc_id doc_id CD cord-286950-j7m69833 5 1 : : : cord-286950-j7m69833 5 2 286950 286950 CD cord-286950-j7m69833 5 3 cord_uid cord_uid NNS cord-286950-j7m69833 5 4 : : : cord-286950-j7m69833 5 5 j7m69833 j7m69833 NNP cord-286950-j7m69833 6 1 Half half PDT cord-286950-j7m69833 6 2 a a DT cord-286950-j7m69833 6 3 decade decade NN cord-286950-j7m69833 6 4 after after IN cord-286950-j7m69833 6 5 the the DT cord-286950-j7m69833 6 6 contentious contentious JJ cord-286950-j7m69833 6 7 “ " `` cord-286950-j7m69833 6 8 gain gain NN cord-286950-j7m69833 6 9 - - HYPH cord-286950-j7m69833 6 10 of of IN cord-286950-j7m69833 6 11 - - HYPH cord-286950-j7m69833 6 12 function function NN cord-286950-j7m69833 6 13 ” " '' cord-286950-j7m69833 6 14 ( ( -LRB- cord-286950-j7m69833 6 15 GOF GOF NNP cord-286950-j7m69833 6 16 ) ) -RRB- cord-286950-j7m69833 6 17 debate debate NN cord-286950-j7m69833 6 18 of of IN cord-286950-j7m69833 6 19 2012 2012 CD cord-286950-j7m69833 6 20 that that WDT cord-286950-j7m69833 6 21 followed follow VBD cord-286950-j7m69833 6 22 experimentation experimentation NN cord-286950-j7m69833 6 23 showing show VBG cord-286950-j7m69833 6 24 that that IN cord-286950-j7m69833 6 25 highly highly RB cord-286950-j7m69833 6 26 pathogenic pathogenic JJ cord-286950-j7m69833 6 27 avian avian JJ cord-286950-j7m69833 6 28 influenza influenza NN cord-286950-j7m69833 6 29 virus virus NN cord-286950-j7m69833 6 30 could could MD cord-286950-j7m69833 6 31 become become VB cord-286950-j7m69833 6 32 mammalian mammalian JJ cord-286950-j7m69833 6 33 transmissible transmissible JJ cord-286950-j7m69833 6 34 , , , cord-286950-j7m69833 6 35 it -PRON- PRP cord-286950-j7m69833 6 36 is be VBZ cord-286950-j7m69833 6 37 possible possible JJ cord-286950-j7m69833 6 38 to to TO cord-286950-j7m69833 6 39 reflect reflect VB cord-286950-j7m69833 6 40 on on IN cord-286950-j7m69833 6 41 the the DT cord-286950-j7m69833 6 42 arguments argument NNS cord-286950-j7m69833 6 43 for for IN cord-286950-j7m69833 6 44 and and CC cord-286950-j7m69833 6 45 against against IN cord-286950-j7m69833 6 46 this this DT cord-286950-j7m69833 6 47 type type NN cord-286950-j7m69833 6 48 of of IN cord-286950-j7m69833 6 49 research research NN cord-286950-j7m69833 6 50 . . . cord-286950-j7m69833 7 1 In in IN cord-286950-j7m69833 7 2 this this DT cord-286950-j7m69833 7 3 essay essay NN cord-286950-j7m69833 7 4 we -PRON- PRP cord-286950-j7m69833 7 5 argue argue VBP cord-286950-j7m69833 7 6 that that IN cord-286950-j7m69833 7 7 GOF GOF NNP cord-286950-j7m69833 7 8 - - HYPH cord-286950-j7m69833 7 9 type type NN cord-286950-j7m69833 7 10 experiments experiment NNS cord-286950-j7m69833 7 11 have have VBP cord-286950-j7m69833 7 12 already already RB cord-286950-j7m69833 7 13 produced produce VBN cord-286950-j7m69833 7 14 important important JJ cord-286950-j7m69833 7 15 information information NN cord-286950-j7m69833 7 16 not not RB cord-286950-j7m69833 7 17 available available JJ cord-286950-j7m69833 7 18 from from IN cord-286950-j7m69833 7 19 any any DT cord-286950-j7m69833 7 20 other other JJ cord-286950-j7m69833 7 21 source source NN cord-286950-j7m69833 7 22 while while IN cord-286950-j7m69833 7 23 also also RB cord-286950-j7m69833 7 24 providing provide VBG cord-286950-j7m69833 7 25 information information NN cord-286950-j7m69833 7 26 on on IN cord-286950-j7m69833 7 27 pathogenesis pathogenesis NN cord-286950-j7m69833 7 28 and and CC cord-286950-j7m69833 7 29 the the DT cord-286950-j7m69833 7 30 requirements requirement NNS cord-286950-j7m69833 7 31 for for IN cord-286950-j7m69833 7 32 optimizing optimize VBG cord-286950-j7m69833 7 33 strains strain NNS cord-286950-j7m69833 7 34 for for IN cord-286950-j7m69833 7 35 vaccine vaccine NN cord-286950-j7m69833 7 36 production production NN cord-286950-j7m69833 7 37 . . . cord-286950-j7m69833 8 1 We -PRON- PRP cord-286950-j7m69833 8 2 analyze analyze VBP cord-286950-j7m69833 8 3 the the DT cord-286950-j7m69833 8 4 moral moral JJ cord-286950-j7m69833 8 5 arguments argument NNS cord-286950-j7m69833 8 6 against against IN cord-286950-j7m69833 8 7 GOF GOF NNP cord-286950-j7m69833 8 8 and and CC cord-286950-j7m69833 8 9 find find VB cord-286950-j7m69833 8 10 them -PRON- PRP cord-286950-j7m69833 8 11 less less RBR cord-286950-j7m69833 8 12 compelling compelling JJ cord-286950-j7m69833 8 13 for for IN cord-286950-j7m69833 8 14 a a DT cord-286950-j7m69833 8 15 variety variety NN cord-286950-j7m69833 8 16 of of IN cord-286950-j7m69833 8 17 reasons reason NNS cord-286950-j7m69833 8 18 ranging range VBG cord-286950-j7m69833 8 19 from from IN cord-286950-j7m69833 8 20 the the DT cord-286950-j7m69833 8 21 uncertainty uncertainty NN cord-286950-j7m69833 8 22 of of IN cord-286950-j7m69833 8 23 risk risk NN cord-286950-j7m69833 8 24 - - HYPH cord-286950-j7m69833 8 25 benefit benefit NN cord-286950-j7m69833 8 26 analysis analysis NN cord-286950-j7m69833 8 27 to to IN cord-286950-j7m69833 8 28 the the DT cord-286950-j7m69833 8 29 reduced reduce VBN cord-286950-j7m69833 8 30 likelihood likelihood NN cord-286950-j7m69833 8 31 of of IN cord-286950-j7m69833 8 32 accidents accident NNS cord-286950-j7m69833 8 33 given give VBN cord-286950-j7m69833 8 34 the the DT cord-286950-j7m69833 8 35 enhanced enhance VBN cord-286950-j7m69833 8 36 biosafety biosafety NN cord-286950-j7m69833 8 37 and and CC cord-286950-j7m69833 8 38 biosecurity biosecurity NN cord-286950-j7m69833 8 39 protocols protocol NNS cord-286950-j7m69833 8 40 currently currently RB cord-286950-j7m69833 8 41 in in IN cord-286950-j7m69833 8 42 place place NN cord-286950-j7m69833 8 43 . . . cord-286950-j7m69833 9 1 In in IN cord-286950-j7m69833 9 2 our -PRON- PRP$ cord-286950-j7m69833 9 3 view view NN cord-286950-j7m69833 9 4 the the DT cord-286950-j7m69833 9 5 most most RBS cord-286950-j7m69833 9 6 important important JJ cord-286950-j7m69833 9 7 consequence consequence NN cord-286950-j7m69833 9 8 of of IN cord-286950-j7m69833 9 9 the the DT cord-286950-j7m69833 9 10 GOF GOF NNP cord-286950-j7m69833 9 11 debate debate NN cord-286950-j7m69833 9 12 is be VBZ cord-286950-j7m69833 9 13 that that IN cord-286950-j7m69833 9 14 it -PRON- PRP cord-286950-j7m69833 9 15 brought bring VBD cord-286950-j7m69833 9 16 renewed renew VBN cord-286950-j7m69833 9 17 attention attention NN cord-286950-j7m69833 9 18 to to IN cord-286950-j7m69833 9 19 biosafety biosafety NN cord-286950-j7m69833 9 20 protocols protocol NNS cord-286950-j7m69833 9 21 and and CC cord-286950-j7m69833 9 22 ushered usher VBD cord-286950-j7m69833 9 23 innovation innovation NN cord-286950-j7m69833 9 24 in in IN cord-286950-j7m69833 9 25 answering answer VBG cord-286950-j7m69833 9 26 the the DT cord-286950-j7m69833 9 27 relevant relevant JJ cord-286950-j7m69833 9 28 biological biological JJ cord-286950-j7m69833 9 29 questions question NNS cord-286950-j7m69833 9 30 with with IN cord-286950-j7m69833 9 31 greater great JJR cord-286950-j7m69833 9 32 safety safety NN cord-286950-j7m69833 9 33 . . . cord-286950-j7m69833 10 1 We -PRON- PRP cord-286950-j7m69833 10 2 conclude conclude VBP cord-286950-j7m69833 10 3 that that IN cord-286950-j7m69833 10 4 GOF GOF NNP cord-286950-j7m69833 10 5 experiments experiment NNS cord-286950-j7m69833 10 6 should should MD cord-286950-j7m69833 10 7 go go VB cord-286950-j7m69833 10 8 forward forward RB cord-286950-j7m69833 10 9 provided provide VBN cord-286950-j7m69833 10 10 that that IN cord-286950-j7m69833 10 11 necessary necessary JJ cord-286950-j7m69833 10 12 biosafety biosafety NN cord-286950-j7m69833 10 13 and and CC cord-286950-j7m69833 10 14 biosecurity biosecurity NN cord-286950-j7m69833 10 15 conditions condition NNS cord-286950-j7m69833 10 16 are be VBP cord-286950-j7m69833 10 17 in in IN cord-286950-j7m69833 10 18 place place NN cord-286950-j7m69833 10 19 . . . cord-286950-j7m69833 11 1 At at IN cord-286950-j7m69833 11 2 the the DT cord-286950-j7m69833 11 3 turn turn NN cord-286950-j7m69833 11 4 of of IN cord-286950-j7m69833 11 5 the the DT cord-286950-j7m69833 11 6 twenty twenty CD cord-286950-j7m69833 11 7 - - HYPH cord-286950-j7m69833 11 8 first first JJ cord-286950-j7m69833 11 9 century century NN cord-286950-j7m69833 11 10 , , , cord-286950-j7m69833 11 11 public public JJ cord-286950-j7m69833 11 12 health health NN cord-286950-j7m69833 11 13 officials official NNS cord-286950-j7m69833 11 14 began begin VBD cord-286950-j7m69833 11 15 to to TO cord-286950-j7m69833 11 16 notice notice VB cord-286950-j7m69833 11 17 an an DT cord-286950-j7m69833 11 18 increase increase NN cord-286950-j7m69833 11 19 in in IN cord-286950-j7m69833 11 20 the the DT cord-286950-j7m69833 11 21 number number NN cord-286950-j7m69833 11 22 of of IN cord-286950-j7m69833 11 23 human human JJ cord-286950-j7m69833 11 24 infections infection NNS cord-286950-j7m69833 11 25 with with IN cord-286950-j7m69833 11 26 highly highly RB cord-286950-j7m69833 11 27 pathogenic pathogenic JJ cord-286950-j7m69833 11 28 avian avian JJ cord-286950-j7m69833 11 29 H5N1 H5N1 NNP cord-286950-j7m69833 11 30 influenza influenza NN cord-286950-j7m69833 11 31 virus virus NN cord-286950-j7m69833 11 32 originating originate VBG cord-286950-j7m69833 11 33 from from IN cord-286950-j7m69833 11 34 birds bird NNS cord-286950-j7m69833 11 35 in in IN cord-286950-j7m69833 11 36 close close JJ cord-286950-j7m69833 11 37 proximity proximity NN cord-286950-j7m69833 11 38 to to IN cord-286950-j7m69833 11 39 people people NNS cord-286950-j7m69833 11 40 . . . cord-286950-j7m69833 12 1 The the DT cord-286950-j7m69833 12 2 possibility possibility NN cord-286950-j7m69833 12 3 of of IN cord-286950-j7m69833 12 4 influenza influenza NN cord-286950-j7m69833 12 5 pandemics pandemic NNS cord-286950-j7m69833 12 6 is be VBZ cord-286950-j7m69833 12 7 always always RB cord-286950-j7m69833 12 8 a a DT cord-286950-j7m69833 12 9 concern concern NN cord-286950-j7m69833 12 10 , , , cord-286950-j7m69833 12 11 but but CC cord-286950-j7m69833 12 12 this this DT cord-286950-j7m69833 12 13 zoonotic zoonotic JJ cord-286950-j7m69833 12 14 jump jump NN cord-286950-j7m69833 12 15 seemed seem VBD cord-286950-j7m69833 12 16 particularly particularly RB cord-286950-j7m69833 12 17 worrisome worrisome JJ cord-286950-j7m69833 12 18 because because IN cord-286950-j7m69833 12 19 the the DT cord-286950-j7m69833 12 20 case case NN cord-286950-j7m69833 12 21 fatality fatality NN cord-286950-j7m69833 12 22 rate rate NN cord-286950-j7m69833 12 23 ( ( -LRB- cord-286950-j7m69833 12 24 CFR CFR NNP cord-286950-j7m69833 12 25 ) ) -RRB- cord-286950-j7m69833 12 26 was be VBD cord-286950-j7m69833 12 27 approximately approximately RB cord-286950-j7m69833 12 28 60 60 CD cord-286950-j7m69833 12 29 % % NN cord-286950-j7m69833 12 30 . . . cord-286950-j7m69833 13 1 Fortunately fortunately RB cord-286950-j7m69833 13 2 , , , cord-286950-j7m69833 13 3 the the DT cord-286950-j7m69833 13 4 virus virus NN cord-286950-j7m69833 13 5 did do VBD cord-286950-j7m69833 13 6 not not RB cord-286950-j7m69833 13 7 acquire acquire VB cord-286950-j7m69833 13 8 mammalian mammalian JJ cord-286950-j7m69833 13 9 transmissibility transmissibility NN cord-286950-j7m69833 13 10 , , , cord-286950-j7m69833 13 11 and and CC cord-286950-j7m69833 13 12 there there EX cord-286950-j7m69833 13 13 were be VBD cord-286950-j7m69833 13 14 no no DT cord-286950-j7m69833 13 15 confirmed confirm VBN cord-286950-j7m69833 13 16 examples example NNS cord-286950-j7m69833 13 17 of of IN cord-286950-j7m69833 13 18 human human NN cord-286950-j7m69833 13 19 - - HYPH cord-286950-j7m69833 13 20 to to IN cord-286950-j7m69833 13 21 - - HYPH cord-286950-j7m69833 13 22 human human JJ cord-286950-j7m69833 13 23 spread spread NN cord-286950-j7m69833 13 24 . . . cord-286950-j7m69833 14 1 Nevertheless nevertheless RB cord-286950-j7m69833 14 2 , , , cord-286950-j7m69833 14 3 there there EX cord-286950-j7m69833 14 4 was be VBD cord-286950-j7m69833 14 5 great great JJ cord-286950-j7m69833 14 6 concern concern NN cord-286950-j7m69833 14 7 that that IN cord-286950-j7m69833 14 8 if if IN cord-286950-j7m69833 14 9 the the DT cord-286950-j7m69833 14 10 virus virus NN cord-286950-j7m69833 14 11 did do VBD cord-286950-j7m69833 14 12 acquire acquire VB cord-286950-j7m69833 14 13 human human JJ cord-286950-j7m69833 14 14 transmissibility transmissibility NN cord-286950-j7m69833 14 15 and and CC cord-286950-j7m69833 14 16 maintained maintain VBD cord-286950-j7m69833 14 17 such such PDT cord-286950-j7m69833 14 18 a a DT cord-286950-j7m69833 14 19 high high JJ cord-286950-j7m69833 14 20 CFR CFR NNP cord-286950-j7m69833 14 21 , , , cord-286950-j7m69833 14 22 the the DT cord-286950-j7m69833 14 23 world world NN cord-286950-j7m69833 14 24 could could MD cord-286950-j7m69833 14 25 face face VB cord-286950-j7m69833 14 26 a a DT cord-286950-j7m69833 14 27 public public JJ cord-286950-j7m69833 14 28 health health NN cord-286950-j7m69833 14 29 emergency emergency NN cord-286950-j7m69833 14 30 of of IN cord-286950-j7m69833 14 31 unprecedented unprecedented JJ cord-286950-j7m69833 14 32 danger danger NN cord-286950-j7m69833 14 33 . . . cord-286950-j7m69833 15 1 For for IN cord-286950-j7m69833 15 2 comparison comparison NN cord-286950-j7m69833 15 3 , , , cord-286950-j7m69833 15 4 the the DT cord-286950-j7m69833 15 5 CFR CFR NNP cord-286950-j7m69833 15 6 during during IN cord-286950-j7m69833 15 7 the the DT cord-286950-j7m69833 15 8 1918 1918 CD cord-286950-j7m69833 15 9 influenza influenza NN cord-286950-j7m69833 15 10 epidemic epidemic NN cord-286950-j7m69833 15 11 , , , cord-286950-j7m69833 15 12 which which WDT cord-286950-j7m69833 15 13 many many JJ cord-286950-j7m69833 15 14 believe believe VBP cord-286950-j7m69833 15 15 to to TO cord-286950-j7m69833 15 16 be be VB cord-286950-j7m69833 15 17 the the DT cord-286950-j7m69833 15 18 worst bad JJS cord-286950-j7m69833 15 19 influenza influenza NN cord-286950-j7m69833 15 20 pandemic pandemic NN cord-286950-j7m69833 15 21 in in IN cord-286950-j7m69833 15 22 history history NN cord-286950-j7m69833 15 23 , , , cord-286950-j7m69833 15 24 was be VBD cord-286950-j7m69833 15 25 approximately approximately RB cord-286950-j7m69833 15 26 2.5 2.5 CD cord-286950-j7m69833 15 27 % % NN cord-286950-j7m69833 15 28 . . . cord-286950-j7m69833 16 1 Another another DT cord-286950-j7m69833 16 2 development development NN cord-286950-j7m69833 16 3 in in IN cord-286950-j7m69833 16 4 the the DT cord-286950-j7m69833 16 5 mid-2000s mid-2000s NN cord-286950-j7m69833 16 6 was be VBD cord-286950-j7m69833 16 7 the the DT cord-286950-j7m69833 16 8 creation creation NN cord-286950-j7m69833 16 9 in in IN cord-286950-j7m69833 16 10 the the DT cord-286950-j7m69833 16 11 USA USA NNP cord-286950-j7m69833 16 12 of of IN cord-286950-j7m69833 16 13 the the DT cord-286950-j7m69833 16 14 National National NNP cord-286950-j7m69833 16 15 Science Science NNP cord-286950-j7m69833 16 16 Advisory Advisory NNP cord-286950-j7m69833 16 17 Board Board NNP cord-286950-j7m69833 16 18 for for IN cord-286950-j7m69833 16 19 Biosecurity Biosecurity NNP cord-286950-j7m69833 16 20 ( ( -LRB- cord-286950-j7m69833 16 21 NSABB NSABB NNP cord-286950-j7m69833 16 22 ) ) -RRB- cord-286950-j7m69833 16 23 , , , cord-286950-j7m69833 16 24 whose whose WP$ cord-286950-j7m69833 16 25 charge charge NN cord-286950-j7m69833 16 26 was be VBD cord-286950-j7m69833 16 27 to to TO cord-286950-j7m69833 16 28 advise advise VB cord-286950-j7m69833 16 29 the the DT cord-286950-j7m69833 16 30 US US NNP cord-286950-j7m69833 16 31 government government NN cord-286950-j7m69833 16 32 on on IN cord-286950-j7m69833 16 33 so so RB cord-286950-j7m69833 16 34 - - HYPH cord-286950-j7m69833 16 35 called call VBN cord-286950-j7m69833 16 36 " " `` cord-286950-j7m69833 16 37 dual dual JJ cord-286950-j7m69833 16 38 - - HYPH cord-286950-j7m69833 16 39 use use NN cord-286950-j7m69833 16 40 " " '' cord-286950-j7m69833 16 41 problem problem NN cord-286950-j7m69833 16 42 in in IN cord-286950-j7m69833 16 43 biomedical biomedical JJ cord-286950-j7m69833 16 44 research research NN cord-286950-j7m69833 16 45 : : : cord-286950-j7m69833 16 46 research research NN cord-286950-j7m69833 16 47 being be VBG cord-286950-j7m69833 16 48 performed perform VBN cord-286950-j7m69833 16 49 with with IN cord-286950-j7m69833 16 50 beneficial beneficial JJ cord-286950-j7m69833 16 51 goals goal NNS cord-286950-j7m69833 16 52 in in IN cord-286950-j7m69833 16 53 mind mind NN cord-286950-j7m69833 16 54 , , , cord-286950-j7m69833 16 55 but but CC cord-286950-j7m69833 16 56 the the DT cord-286950-j7m69833 16 57 results result NNS cord-286950-j7m69833 16 58 of of IN cord-286950-j7m69833 16 59 which which WDT cord-286950-j7m69833 16 60 could could MD cord-286950-j7m69833 16 61 be be VB cord-286950-j7m69833 16 62 misused misuse VBN cord-286950-j7m69833 16 63 for for IN cord-286950-j7m69833 16 64 nefarious nefarious JJ cord-286950-j7m69833 16 65 purposes purpose NNS cord-286950-j7m69833 16 66 . . . cord-286950-j7m69833 17 1 The the DT cord-286950-j7m69833 17 2 NSABB NSABB NNP cord-286950-j7m69833 17 3 delved delve VBD cord-286950-j7m69833 17 4 into into IN cord-286950-j7m69833 17 5 the the DT cord-286950-j7m69833 17 6 dual dual JJ cord-286950-j7m69833 17 7 - - HYPH cord-286950-j7m69833 17 8 use use NN cord-286950-j7m69833 17 9 controversy controversy NN cord-286950-j7m69833 17 10 early early RB cord-286950-j7m69833 17 11 in in IN cord-286950-j7m69833 17 12 its -PRON- PRP$ cord-286950-j7m69833 17 13 tenure tenure NN cord-286950-j7m69833 17 14 when when WRB cord-286950-j7m69833 17 15 the the DT cord-286950-j7m69833 17 16 US US NNP cord-286950-j7m69833 17 17 government government NN cord-286950-j7m69833 17 18 asked ask VBD cord-286950-j7m69833 17 19 it -PRON- PRP cord-286950-j7m69833 17 20 to to TO cord-286950-j7m69833 17 21 review review VB cord-286950-j7m69833 17 22 the the DT cord-286950-j7m69833 17 23 paper paper NN cord-286950-j7m69833 17 24 describing describe VBG cord-286950-j7m69833 17 25 the the DT cord-286950-j7m69833 17 26 reconstruction reconstruction NN cord-286950-j7m69833 17 27 of of IN cord-286950-j7m69833 17 28 the the DT cord-286950-j7m69833 17 29 influenza influenza NN cord-286950-j7m69833 17 30 virus virus NN cord-286950-j7m69833 17 31 strain strain NN cord-286950-j7m69833 17 32 responsible responsible JJ cord-286950-j7m69833 17 33 for for IN cord-286950-j7m69833 17 34 the the DT cord-286950-j7m69833 17 35 1918 1918 CD cord-286950-j7m69833 17 36 epidemic epidemic NN cord-286950-j7m69833 17 37 [ [ -LRB- cord-286950-j7m69833 17 38 1 1 CD cord-286950-j7m69833 17 39 ] ] -RRB- cord-286950-j7m69833 17 40 . . . cord-286950-j7m69833 18 1 Although although IN cord-286950-j7m69833 18 2 the the DT cord-286950-j7m69833 18 3 NSABB NSABB NNP cord-286950-j7m69833 18 4 voted vote VBD cord-286950-j7m69833 18 5 to to TO cord-286950-j7m69833 18 6 recommend recommend VB cord-286950-j7m69833 18 7 publication publication NN cord-286950-j7m69833 18 8 , , , cord-286950-j7m69833 18 9 the the DT cord-286950-j7m69833 18 10 editor editor NN cord-286950-j7m69833 18 11 of of IN cord-286950-j7m69833 18 12 Science Science NNP cord-286950-j7m69833 18 13 made make VBD cord-286950-j7m69833 18 14 it -PRON- PRP cord-286950-j7m69833 18 15 clear clear JJ cord-286950-j7m69833 18 16 that that IN cord-286950-j7m69833 18 17 the the DT cord-286950-j7m69833 18 18 journal journal NN cord-286950-j7m69833 18 19 would would MD cord-286950-j7m69833 18 20 have have VB cord-286950-j7m69833 18 21 published publish VBN cord-286950-j7m69833 18 22 the the DT cord-286950-j7m69833 18 23 article article NN cord-286950-j7m69833 18 24 irrespective irrespective RB cord-286950-j7m69833 18 25 of of IN cord-286950-j7m69833 18 26 the the DT cord-286950-j7m69833 18 27 NSABB NSABB NNP cord-286950-j7m69833 18 28 vote vote NN cord-286950-j7m69833 18 29 unless unless IN cord-286950-j7m69833 18 30 the the DT cord-286950-j7m69833 18 31 paper paper NN cord-286950-j7m69833 18 32 was be VBD cord-286950-j7m69833 18 33 classified classify VBN cord-286950-j7m69833 18 34 [ [ -LRB- cord-286950-j7m69833 18 35 2 2 CD cord-286950-j7m69833 18 36 ] ] -RRB- cord-286950-j7m69833 18 37 . . . cord-286950-j7m69833 19 1 For for IN cord-286950-j7m69833 19 2 the the DT cord-286950-j7m69833 19 3 next next JJ cord-286950-j7m69833 19 4 half half NN cord-286950-j7m69833 19 5 decade decade NN cord-286950-j7m69833 19 6 , , , cord-286950-j7m69833 19 7 the the DT cord-286950-j7m69833 19 8 NSABB NSABB NNP cord-286950-j7m69833 19 9 struggled struggle VBD cord-286950-j7m69833 19 10 with with IN cord-286950-j7m69833 19 11 the the DT cord-286950-j7m69833 19 12 problem problem NN cord-286950-j7m69833 19 13 of of IN cord-286950-j7m69833 19 14 how how WRB cord-286950-j7m69833 19 15 to to TO cord-286950-j7m69833 19 16 deal deal VB cord-286950-j7m69833 19 17 with with IN cord-286950-j7m69833 19 18 dual dual JJ cord-286950-j7m69833 19 19 - - HYPH cord-286950-j7m69833 19 20 use use NN cord-286950-j7m69833 19 21 research research NN cord-286950-j7m69833 19 22 in in IN cord-286950-j7m69833 19 23 the the DT cord-286950-j7m69833 19 24 biological biological JJ cord-286950-j7m69833 19 25 sciences science NNS cord-286950-j7m69833 19 26 and and CC cord-286950-j7m69833 19 27 proposed propose VBD cord-286950-j7m69833 19 28 identifying identify VBG cord-286950-j7m69833 19 29 a a DT cord-286950-j7m69833 19 30 small small JJ cord-286950-j7m69833 19 31 subset subset NN cord-286950-j7m69833 19 32 of of IN cord-286950-j7m69833 19 33 science science NN cord-286950-j7m69833 19 34 known know VBN cord-286950-j7m69833 19 35 as as IN cord-286950-j7m69833 19 36 " " `` cord-286950-j7m69833 19 37 dual dual JJ cord-286950-j7m69833 19 38 - - HYPH cord-286950-j7m69833 19 39 use use NN cord-286950-j7m69833 19 40 research research NN cord-286950-j7m69833 19 41 of of IN cord-286950-j7m69833 19 42 concern concern NN cord-286950-j7m69833 19 43 , , , cord-286950-j7m69833 19 44 " " '' cord-286950-j7m69833 19 45 or or CC cord-286950-j7m69833 19 46 DURC DURC NNP cord-286950-j7m69833 19 47 , , , cord-286950-j7m69833 19 48 as as IN cord-286950-j7m69833 19 49 that that DT cord-286950-j7m69833 19 50 domain domain NN cord-286950-j7m69833 19 51 on on IN cord-286950-j7m69833 19 52 which which WDT cord-286950-j7m69833 19 53 to to TO cord-286950-j7m69833 19 54 focus focus VB cord-286950-j7m69833 19 55 efforts effort NNS cord-286950-j7m69833 19 56 . . . cord-286950-j7m69833 20 1 While while IN cord-286950-j7m69833 20 2 the the DT cord-286950-j7m69833 20 3 NSABB NSABB NNP cord-286950-j7m69833 20 4 was be VBD cord-286950-j7m69833 20 5 formulating formulate VBG cord-286950-j7m69833 20 6 DURC DURC NNP cord-286950-j7m69833 20 7 definitions definition NNS cord-286950-j7m69833 20 8 and and CC cord-286950-j7m69833 20 9 devising devise VBG cord-286950-j7m69833 20 10 recommendations recommendation NNS cord-286950-j7m69833 20 11 , , , cord-286950-j7m69833 20 12 two two CD cord-286950-j7m69833 20 13 laboratories laboratory NNS cord-286950-j7m69833 20 14 set set VBN cord-286950-j7m69833 20 15 out out RP cord-286950-j7m69833 20 16 to to TO cord-286950-j7m69833 20 17 experimentally experimentally RB cord-286950-j7m69833 20 18 test test VB cord-286950-j7m69833 20 19 whether whether IN cord-286950-j7m69833 20 20 H5N1 H5N1 NNP cord-286950-j7m69833 20 21 virus virus NN cord-286950-j7m69833 20 22 could could MD cord-286950-j7m69833 20 23 become become VB cord-286950-j7m69833 20 24 transmissible transmissible JJ cord-286950-j7m69833 20 25 in in IN cord-286950-j7m69833 20 26 what what WP cord-286950-j7m69833 20 27 is be VBZ cord-286950-j7m69833 20 28 thought think VBN cord-286950-j7m69833 20 29 to to TO cord-286950-j7m69833 20 30 be be VB cord-286950-j7m69833 20 31 the the DT cord-286950-j7m69833 20 32 best good JJS cord-286950-j7m69833 20 33 animal animal NN cord-286950-j7m69833 20 34 model model NN cord-286950-j7m69833 20 35 for for IN cord-286950-j7m69833 20 36 such such JJ cord-286950-j7m69833 20 37 studies study NNS cord-286950-j7m69833 20 38 , , , cord-286950-j7m69833 20 39 the the DT cord-286950-j7m69833 20 40 ferret ferret NN cord-286950-j7m69833 20 41 . . . cord-286950-j7m69833 21 1 Research research NN cord-286950-j7m69833 21 2 groups group NNS cord-286950-j7m69833 21 3 led lead VBN cord-286950-j7m69833 21 4 by by IN cord-286950-j7m69833 21 5 Yoshi Yoshi NNP cord-286950-j7m69833 21 6 Kawaoka Kawaoka NNP cord-286950-j7m69833 21 7 in in IN cord-286950-j7m69833 21 8 the the DT cord-286950-j7m69833 21 9 USA USA NNP cord-286950-j7m69833 21 10 and and CC cord-286950-j7m69833 21 11 Ron Ron NNP cord-286950-j7m69833 21 12 Fouchier Fouchier NNP cord-286950-j7m69833 21 13 in in IN cord-286950-j7m69833 21 14 the the DT cord-286950-j7m69833 21 15 Netherlands Netherlands NNP cord-286950-j7m69833 21 16 took take VBD cord-286950-j7m69833 21 17 similar similar JJ cord-286950-j7m69833 21 18 approaches approach NNS cord-286950-j7m69833 21 19 albeit albeit IN cord-286950-j7m69833 21 20 with with IN cord-286950-j7m69833 21 21 different different JJ cord-286950-j7m69833 21 22 starting starting NN cord-286950-j7m69833 21 23 strains strain NNS cord-286950-j7m69833 21 24 , , , cord-286950-j7m69833 21 25 first first RB cord-286950-j7m69833 21 26 engineering engineer VBG cord-286950-j7m69833 21 27 the the DT cord-286950-j7m69833 21 28 ability ability NN cord-286950-j7m69833 21 29 of of IN cord-286950-j7m69833 21 30 the the DT cord-286950-j7m69833 21 31 virus virus NN cord-286950-j7m69833 21 32 to to TO cord-286950-j7m69833 21 33 bind bind VB cord-286950-j7m69833 21 34 to to IN cord-286950-j7m69833 21 35 human human JJ cord-286950-j7m69833 21 36 receptors receptor NNS cord-286950-j7m69833 21 37 and and CC cord-286950-j7m69833 21 38 then then RB cord-286950-j7m69833 21 39 serially serially RB cord-286950-j7m69833 21 40 passaging passage VBG cord-286950-j7m69833 21 41 it -PRON- PRP cord-286950-j7m69833 21 42 through through IN cord-286950-j7m69833 21 43 ferrets ferret NNS cord-286950-j7m69833 21 44 . . . cord-286950-j7m69833 22 1 Both both DT cord-286950-j7m69833 22 2 obtained obtain VBD cord-286950-j7m69833 22 3 the the DT cord-286950-j7m69833 22 4 same same JJ cord-286950-j7m69833 22 5 answer answer NN cord-286950-j7m69833 22 6 : : : cord-286950-j7m69833 22 7 the the DT cord-286950-j7m69833 22 8 H5N1 H5N1 NNP cord-286950-j7m69833 22 9 virus virus NN cord-286950-j7m69833 22 10 could could MD cord-286950-j7m69833 22 11 attain attain VB cord-286950-j7m69833 22 12 the the DT cord-286950-j7m69833 22 13 ability ability NN cord-286950-j7m69833 22 14 to to TO cord-286950-j7m69833 22 15 be be VB cord-286950-j7m69833 22 16 transmitted transmit VBN cord-286950-j7m69833 22 17 via via IN cord-286950-j7m69833 22 18 respiratory respiratory JJ cord-286950-j7m69833 22 19 droplets droplet NNS cord-286950-j7m69833 22 20 . . . cord-286950-j7m69833 23 1 They -PRON- PRP cord-286950-j7m69833 23 2 wrote write VBD cord-286950-j7m69833 23 3 manuscripts manuscript NNS cord-286950-j7m69833 23 4 and and CC cord-286950-j7m69833 23 5 submitted submit VBD cord-286950-j7m69833 23 6 them -PRON- PRP cord-286950-j7m69833 23 7 for for IN cord-286950-j7m69833 23 8 publication publication NN cord-286950-j7m69833 23 9 in in IN cord-286950-j7m69833 23 10 Nature Nature NNP cord-286950-j7m69833 23 11 and and CC cord-286950-j7m69833 23 12 Science Science NNP cord-286950-j7m69833 23 13 , , , cord-286950-j7m69833 23 14 respectively respectively RB cord-286950-j7m69833 23 15 [ [ -LRB- cord-286950-j7m69833 23 16 3 3 CD cord-286950-j7m69833 23 17 , , , cord-286950-j7m69833 23 18 4 4 CD cord-286950-j7m69833 23 19 ] ] -RRB- cord-286950-j7m69833 23 20 . . . cord-286950-j7m69833 24 1 In in IN cord-286950-j7m69833 24 2 late late JJ cord-286950-j7m69833 24 3 2011 2011 CD cord-286950-j7m69833 24 4 the the DT cord-286950-j7m69833 24 5 NSABB NSABB NNP cord-286950-j7m69833 24 6 had have VBD cord-286950-j7m69833 24 7 the the DT cord-286950-j7m69833 24 8 opportunity opportunity NN cord-286950-j7m69833 24 9 to to TO cord-286950-j7m69833 24 10 evaluate evaluate VB cord-286950-j7m69833 24 11 its -PRON- PRP$ cord-286950-j7m69833 24 12 policies policy NNS cord-286950-j7m69833 24 13 and and CC cord-286950-j7m69833 24 14 recommendations recommendation NNS cord-286950-j7m69833 24 15 when when WRB cord-286950-j7m69833 24 16 the the DT cord-286950-j7m69833 24 17 US US NNP cord-286950-j7m69833 24 18 government government NN cord-286950-j7m69833 24 19 learned learn VBD cord-286950-j7m69833 24 20 of of IN cord-286950-j7m69833 24 21 the the DT cord-286950-j7m69833 24 22 two two CD cord-286950-j7m69833 24 23 submitted submit VBN cord-286950-j7m69833 24 24 manuscripts manuscript NNS cord-286950-j7m69833 24 25 describing describe VBG cord-286950-j7m69833 24 26 these these DT cord-286950-j7m69833 24 27 high high JJ cord-286950-j7m69833 24 28 pathogenicity pathogenicity NN cord-286950-j7m69833 24 29 avian avian JJ cord-286950-j7m69833 24 30 influenza influenza NN cord-286950-j7m69833 24 31 viruses virus NNS cord-286950-j7m69833 24 32 ( ( -LRB- cord-286950-j7m69833 24 33 HPAIV HPAIV NNP cord-286950-j7m69833 24 34 ) ) -RRB- cord-286950-j7m69833 24 35 that that WDT cord-286950-j7m69833 24 36 had have VBD cord-286950-j7m69833 24 37 been be VBN cord-286950-j7m69833 24 38 made make VBN cord-286950-j7m69833 24 39 mammalian mammalian JJ cord-286950-j7m69833 24 40 transmissible transmissible JJ cord-286950-j7m69833 24 41 : : : cord-286950-j7m69833 24 42 it -PRON- PRP cord-286950-j7m69833 24 43 asked ask VBD cord-286950-j7m69833 24 44 the the DT cord-286950-j7m69833 24 45 NSABB NSABB NNP cord-286950-j7m69833 24 46 to to TO cord-286950-j7m69833 24 47 advise advise VB cord-286950-j7m69833 24 48 it -PRON- PRP cord-286950-j7m69833 24 49 whether whether IN cord-286950-j7m69833 24 50 publication publication NN cord-286950-j7m69833 24 51 was be VBD cord-286950-j7m69833 24 52 wise wise RB cord-286950-j7m69833 24 53 given give VBN cord-286950-j7m69833 24 54 potential potential JJ cord-286950-j7m69833 24 55 biosecurity biosecurity NN cord-286950-j7m69833 24 56 concerns concern NNS cord-286950-j7m69833 24 57 . . . cord-286950-j7m69833 25 1 The the DT cord-286950-j7m69833 25 2 details detail NNS cord-286950-j7m69833 25 3 of of IN cord-286950-j7m69833 25 4 the the DT cord-286950-j7m69833 25 5 deliberations deliberation NNS cord-286950-j7m69833 25 6 of of IN cord-286950-j7m69833 25 7 the the DT cord-286950-j7m69833 25 8 NSABB NSABB NNP cord-286950-j7m69833 25 9 and and CC cord-286950-j7m69833 25 10 its -PRON- PRP$ cord-286950-j7m69833 25 11 ultimate ultimate JJ cord-286950-j7m69833 25 12 decision decision NN cord-286950-j7m69833 25 13 to to TO cord-286950-j7m69833 25 14 recommend recommend VB cord-286950-j7m69833 25 15 publication publication NN cord-286950-j7m69833 25 16 have have VBP cord-286950-j7m69833 25 17 been be VBN cord-286950-j7m69833 25 18 described describe VBN cord-286950-j7m69833 25 19 in in IN cord-286950-j7m69833 25 20 detail detail NN cord-286950-j7m69833 25 21 elsewhere elsewhere RB cord-286950-j7m69833 25 22 , , , cord-286950-j7m69833 25 23 but but CC cord-286950-j7m69833 25 24 briefly briefly RB cord-286950-j7m69833 25 25 , , , cord-286950-j7m69833 25 26 the the DT cord-286950-j7m69833 25 27 NSABB NSABB NNP cord-286950-j7m69833 25 28 determined determine VBD cord-286950-j7m69833 25 29 that that IN cord-286950-j7m69833 25 30 the the DT cord-286950-j7m69833 25 31 benefits benefit NNS cord-286950-j7m69833 25 32 of of IN cord-286950-j7m69833 25 33 the the DT cord-286950-j7m69833 25 34 research research NN cord-286950-j7m69833 25 35 outweighed outweigh VBD cord-286950-j7m69833 25 36 the the DT cord-286950-j7m69833 25 37 biosecurity biosecurity NN cord-286950-j7m69833 25 38 risks risk NNS cord-286950-j7m69833 25 39 [ [ -LRB- cord-286950-j7m69833 25 40 5 5 CD cord-286950-j7m69833 25 41 ] ] -RRB- cord-286950-j7m69833 25 42 . . . cord-286950-j7m69833 26 1 Hence hence RB cord-286950-j7m69833 26 2 , , , cord-286950-j7m69833 26 3 the the DT cord-286950-j7m69833 26 4 first first JJ cord-286950-j7m69833 26 5 round round NN cord-286950-j7m69833 26 6 of of IN cord-286950-j7m69833 26 7 the the DT cord-286950-j7m69833 26 8 controversy controversy NN cord-286950-j7m69833 26 9 was be VBD cord-286950-j7m69833 26 10 focused focus VBN cord-286950-j7m69833 26 11 primarily primarily RB cord-286950-j7m69833 26 12 on on IN cord-286950-j7m69833 26 13 biosecurity biosecurity NN cord-286950-j7m69833 26 14 issues issue NNS cord-286950-j7m69833 26 15 . . . cord-286950-j7m69833 27 1 After after IN cord-286950-j7m69833 27 2 the the DT cord-286950-j7m69833 27 3 2012 2012 CD cord-286950-j7m69833 27 4 decision decision NN cord-286950-j7m69833 27 5 on on IN cord-286950-j7m69833 27 6 the the DT cord-286950-j7m69833 27 7 two two CD cord-286950-j7m69833 27 8 influenza influenza NN cord-286950-j7m69833 27 9 papers paper NNS cord-286950-j7m69833 27 10 , , , cord-286950-j7m69833 27 11 the the DT cord-286950-j7m69833 27 12 situation situation NN cord-286950-j7m69833 27 13 quieted quiet VBD cord-286950-j7m69833 27 14 for for IN cord-286950-j7m69833 27 15 a a DT cord-286950-j7m69833 27 16 couple couple NN cord-286950-j7m69833 27 17 of of IN cord-286950-j7m69833 27 18 years year NNS cord-286950-j7m69833 27 19 until until IN cord-286950-j7m69833 27 20 a a DT cord-286950-j7m69833 27 21 series series NN cord-286950-j7m69833 27 22 of of IN cord-286950-j7m69833 27 23 biosafety biosafety NN cord-286950-j7m69833 27 24 lapses lapse NNS cord-286950-j7m69833 27 25 at at IN cord-286950-j7m69833 27 26 US US NNP cord-286950-j7m69833 27 27 government government NN cord-286950-j7m69833 27 28 laboratories laboratory NNS cord-286950-j7m69833 27 29 at at IN cord-286950-j7m69833 27 30 the the DT cord-286950-j7m69833 27 31 CDC CDC NNP cord-286950-j7m69833 27 32 and and CC cord-286950-j7m69833 27 33 the the DT cord-286950-j7m69833 27 34 NIH NIH NNP cord-286950-j7m69833 27 35 received receive VBD cord-286950-j7m69833 27 36 rekindled rekindled JJ cord-286950-j7m69833 27 37 interest interest NN cord-286950-j7m69833 27 38 on on IN cord-286950-j7m69833 27 39 the the DT cord-286950-j7m69833 27 40 problem problem NN cord-286950-j7m69833 27 41 . . . cord-286950-j7m69833 28 1 These these DT cord-286950-j7m69833 28 2 laboratory laboratory NN cord-286950-j7m69833 28 3 incidents incident NNS cord-286950-j7m69833 28 4 received receive VBD cord-286950-j7m69833 28 5 a a DT cord-286950-j7m69833 28 6 high high JJ cord-286950-j7m69833 28 7 degree degree NN cord-286950-j7m69833 28 8 of of IN cord-286950-j7m69833 28 9 public public JJ cord-286950-j7m69833 28 10 attention attention NN cord-286950-j7m69833 28 11 , , , cord-286950-j7m69833 28 12 spearheaded spearhead VBN cord-286950-j7m69833 28 13 by by IN cord-286950-j7m69833 28 14 the the DT cord-286950-j7m69833 28 15 reporting reporting NN cord-286950-j7m69833 28 16 of of IN cord-286950-j7m69833 28 17 Alison Alison NNP cord-286950-j7m69833 28 18 Young Young NNP cord-286950-j7m69833 28 19 at at IN cord-286950-j7m69833 28 20 USA USA NNP cord-286950-j7m69833 28 21 Today Today NNP cord-286950-j7m69833 28 22 . . . cord-286950-j7m69833 29 1 This this DT cord-286950-j7m69833 29 2 conjunction conjunction NN cord-286950-j7m69833 29 3 of of IN cord-286950-j7m69833 29 4 laboratory laboratory NN cord-286950-j7m69833 29 5 accidents accident NNS cord-286950-j7m69833 29 6 together together RB cord-286950-j7m69833 29 7 with with IN cord-286950-j7m69833 29 8 additional additional JJ cord-286950-j7m69833 29 9 follow follow NN cord-286950-j7m69833 29 10 - - HYPH cord-286950-j7m69833 29 11 up up NN cord-286950-j7m69833 29 12 publications publication NNS cord-286950-j7m69833 29 13 [ [ -LRB- cord-286950-j7m69833 30 1 e.g. e.g. RB cord-286950-j7m69833 30 2 , , , cord-286950-j7m69833 30 3 6 6 CD cord-286950-j7m69833 30 4 ] ] -RRB- cord-286950-j7m69833 30 5 puts put VBZ cord-286950-j7m69833 30 6 the the DT cord-286950-j7m69833 30 7 H5N1 H5N1 NNP cord-286950-j7m69833 30 8 story story NN cord-286950-j7m69833 30 9 in in IN cord-286950-j7m69833 30 10 a a DT cord-286950-j7m69833 30 11 new new JJ cord-286950-j7m69833 30 12 light light NN cord-286950-j7m69833 30 13 , , , cord-286950-j7m69833 30 14 namely namely RB cord-286950-j7m69833 30 15 , , , cord-286950-j7m69833 30 16 whether whether IN cord-286950-j7m69833 30 17 similar similar JJ cord-286950-j7m69833 30 18 experiments experiment NNS cord-286950-j7m69833 30 19 in in IN cord-286950-j7m69833 30 20 which which WDT cord-286950-j7m69833 30 21 new new JJ cord-286950-j7m69833 30 22 phenotypes phenotype NNS cord-286950-j7m69833 30 23 are be VBP cord-286950-j7m69833 30 24 added add VBN cord-286950-j7m69833 30 25 to to IN cord-286950-j7m69833 30 26 pathogens pathogen NNS cord-286950-j7m69833 30 27 , , , cord-286950-j7m69833 30 28 gain gain NN cord-286950-j7m69833 30 29 - - HYPH cord-286950-j7m69833 30 30 of of IN cord-286950-j7m69833 30 31 - - HYPH cord-286950-j7m69833 30 32 function function NN cord-286950-j7m69833 30 33 ( ( -LRB- cord-286950-j7m69833 30 34 GOF GOF NNP cord-286950-j7m69833 30 35 ) ) -RRB- cord-286950-j7m69833 30 36 studies study NNS cord-286950-j7m69833 30 37 , , , cord-286950-j7m69833 30 38 could could MD cord-286950-j7m69833 30 39 be be VB cord-286950-j7m69833 30 40 conducted conduct VBN cord-286950-j7m69833 30 41 safely safely RB cord-286950-j7m69833 30 42 and and CC cord-286950-j7m69833 30 43 whether whether IN cord-286950-j7m69833 30 44 they -PRON- PRP cord-286950-j7m69833 30 45 should should MD cord-286950-j7m69833 30 46 be be VB cord-286950-j7m69833 30 47 pursued pursue VBN cord-286950-j7m69833 30 48 at at RB cord-286950-j7m69833 30 49 all all RB cord-286950-j7m69833 30 50 . . . cord-286950-j7m69833 31 1 Confronted confront VBN cord-286950-j7m69833 31 2 with with IN cord-286950-j7m69833 31 3 a a DT cord-286950-j7m69833 31 4 public public JJ cord-286950-j7m69833 31 5 outcry outcry NN cord-286950-j7m69833 31 6 combined combine VBN cord-286950-j7m69833 31 7 with with IN cord-286950-j7m69833 31 8 a a DT cord-286950-j7m69833 31 9 serious serious JJ cord-286950-j7m69833 31 10 scientific scientific JJ cord-286950-j7m69833 31 11 debate debate NN cord-286950-j7m69833 31 12 on on IN cord-286950-j7m69833 31 13 the the DT cord-286950-j7m69833 31 14 benefits benefit NNS cord-286950-j7m69833 31 15 and and CC cord-286950-j7m69833 31 16 risks risk NNS cord-286950-j7m69833 31 17 of of IN cord-286950-j7m69833 31 18 GOF GOF NNP cord-286950-j7m69833 31 19 - - HYPH cord-286950-j7m69833 31 20 type type NN cord-286950-j7m69833 31 21 experiments experiment NNS cord-286950-j7m69833 31 22 , , , cord-286950-j7m69833 31 23 in in IN cord-286950-j7m69833 31 24 2014 2014 CD cord-286950-j7m69833 31 25 the the DT cord-286950-j7m69833 31 26 NIH NIH NNP cord-286950-j7m69833 31 27 , , , cord-286950-j7m69833 31 28 which which WDT cord-286950-j7m69833 31 29 has have VBZ cord-286950-j7m69833 31 30 administrative administrative JJ cord-286950-j7m69833 31 31 responsibility responsibility NN cord-286950-j7m69833 31 32 for for IN cord-286950-j7m69833 31 33 the the DT cord-286950-j7m69833 31 34 NSABB NSABB NNP cord-286950-j7m69833 31 35 , , , cord-286950-j7m69833 31 36 imposed impose VBD cord-286950-j7m69833 31 37 a a DT cord-286950-j7m69833 31 38 moratorium moratorium NN cord-286950-j7m69833 31 39 on on IN cord-286950-j7m69833 31 40 US US NNP cord-286950-j7m69833 31 41 - - HYPH cord-286950-j7m69833 31 42 funded fund VBN cord-286950-j7m69833 31 43 GOF GOF NNP cord-286950-j7m69833 31 44 experiments experiment NNS cord-286950-j7m69833 31 45 with with IN cord-286950-j7m69833 31 46 " " `` cord-286950-j7m69833 31 47 pathogens pathogen NNS cord-286950-j7m69833 31 48 of of IN cord-286950-j7m69833 31 49 pandemic pandemic NN cord-286950-j7m69833 31 50 potential potential NN cord-286950-j7m69833 31 51 ( ( -LRB- cord-286950-j7m69833 31 52 PPP PPP NNP cord-286950-j7m69833 31 53 ) ) -RRB- cord-286950-j7m69833 31 54 , , , cord-286950-j7m69833 31 55 " " `` cord-286950-j7m69833 31 56 those those DT cord-286950-j7m69833 31 57 being be VBG cord-286950-j7m69833 31 58 influenza influenza NN cord-286950-j7m69833 31 59 virus virus NN cord-286950-j7m69833 31 60 , , , cord-286950-j7m69833 31 61 severe severe JJ cord-286950-j7m69833 31 62 acute acute JJ cord-286950-j7m69833 31 63 respiratory respiratory JJ cord-286950-j7m69833 31 64 syndrome syndrome NN cord-286950-j7m69833 31 65 ( ( -LRB- cord-286950-j7m69833 31 66 SARS SARS NNP cord-286950-j7m69833 31 67 ) ) -RRB- cord-286950-j7m69833 31 68 coronavirus coronavirus NN cord-286950-j7m69833 31 69 ( ( -LRB- cord-286950-j7m69833 31 70 SARS SARS NNP cord-286950-j7m69833 31 71 - - HYPH cord-286950-j7m69833 31 72 CoV CoV NNP cord-286950-j7m69833 31 73 ) ) -RRB- cord-286950-j7m69833 31 74 , , , cord-286950-j7m69833 31 75 and and CC cord-286950-j7m69833 31 76 Middle Middle NNP cord-286950-j7m69833 31 77 East East NNP cord-286950-j7m69833 31 78 respiratory respiratory JJ cord-286950-j7m69833 31 79 syndrome syndrome NN cord-286950-j7m69833 31 80 ( ( -LRB- cord-286950-j7m69833 31 81 MERS MERS NNP cord-286950-j7m69833 31 82 ) ) -RRB- cord-286950-j7m69833 31 83 coronavirus coronavirus NN cord-286950-j7m69833 31 84 ( ( -LRB- cord-286950-j7m69833 31 85 MERS MERS NNP cord-286950-j7m69833 31 86 - - HYPH cord-286950-j7m69833 31 87 CoV CoV NNP cord-286950-j7m69833 31 88 ) ) -RRB- cord-286950-j7m69833 31 89 . . . cord-286950-j7m69833 32 1 While while IN cord-286950-j7m69833 32 2 SARS SARS NNP cord-286950-j7m69833 32 3 - - HYPH cord-286950-j7m69833 32 4 CoV CoV NNP cord-286950-j7m69833 32 5 had have VBD cord-286950-j7m69833 32 6 disappeared disappear VBN cord-286950-j7m69833 32 7 from from IN cord-286950-j7m69833 32 8 the the DT cord-286950-j7m69833 32 9 human human JJ cord-286950-j7m69833 32 10 population population NN cord-286950-j7m69833 32 11 due due IN cord-286950-j7m69833 32 12 to to IN cord-286950-j7m69833 32 13 a a DT cord-286950-j7m69833 32 14 highly highly RB cord-286950-j7m69833 32 15 successful successful JJ cord-286950-j7m69833 32 16 public public JJ cord-286950-j7m69833 32 17 health health NN cord-286950-j7m69833 32 18 containment containment NN cord-286950-j7m69833 32 19 endeavor endeavor NN cord-286950-j7m69833 32 20 , , , cord-286950-j7m69833 32 21 the the DT cord-286950-j7m69833 32 22 MERS MERS NNP cord-286950-j7m69833 32 23 - - HYPH cord-286950-j7m69833 32 24 CoV CoV NNP cord-286950-j7m69833 32 25 outbreak outbreak NN cord-286950-j7m69833 32 26 had have VBD cord-286950-j7m69833 32 27 emerged emerge VBN cord-286950-j7m69833 32 28 in in IN cord-286950-j7m69833 32 29 the the DT cord-286950-j7m69833 32 30 Middle Middle NNP cord-286950-j7m69833 32 31 East East NNP cord-286950-j7m69833 32 32 and and CC cord-286950-j7m69833 32 33 was be VBD cord-286950-j7m69833 32 34 ( ( -LRB- cord-286950-j7m69833 32 35 and and CC cord-286950-j7m69833 32 36 still still RB cord-286950-j7m69833 32 37 is be VBZ cord-286950-j7m69833 32 38 ) ) -RRB- cord-286950-j7m69833 32 39 ongoing ongoing JJ cord-286950-j7m69833 32 40 at at IN cord-286950-j7m69833 32 41 the the DT cord-286950-j7m69833 32 42 time time NN cord-286950-j7m69833 32 43 . . . cord-286950-j7m69833 33 1 The the DT cord-286950-j7m69833 33 2 US US NNP cord-286950-j7m69833 33 3 government government NN cord-286950-j7m69833 33 4 also also RB cord-286950-j7m69833 33 5 charged charge VBD cord-286950-j7m69833 33 6 the the DT cord-286950-j7m69833 33 7 NSABB NSABB NNP cord-286950-j7m69833 33 8 with with IN cord-286950-j7m69833 33 9 making make VBG cord-286950-j7m69833 33 10 recommendations recommendation NNS cord-286950-j7m69833 33 11 about about IN cord-286950-j7m69833 33 12 the the DT cord-286950-j7m69833 33 13 future future NN cord-286950-j7m69833 33 14 of of IN cord-286950-j7m69833 33 15 GOF GOF NNP cord-286950-j7m69833 33 16 research research NN cord-286950-j7m69833 33 17 ( ( -LRB- cord-286950-j7m69833 33 18 https://www.phe.gov/s3/dualuse/Documents/ https://www.phe.gov/s3/dualuse/documents/ UH cord-286950-j7m69833 33 19 gain-of-function.pdf gain-of-function.pdf NNP cord-286950-j7m69833 33 20 ) ) -RRB- cord-286950-j7m69833 33 21 . . . cord-286950-j7m69833 34 1 We -PRON- PRP cord-286950-j7m69833 34 2 have have VBP cord-286950-j7m69833 34 3 summarized summarize VBN cord-286950-j7m69833 34 4 the the DT cord-286950-j7m69833 34 5 events event NNS cord-286950-j7m69833 34 6 of of IN cord-286950-j7m69833 34 7 2014 2014 CD cord-286950-j7m69833 34 8 in in IN cord-286950-j7m69833 34 9 a a DT cord-286950-j7m69833 34 10 series series NN cord-286950-j7m69833 34 11 of of IN cord-286950-j7m69833 34 12 papers paper NNS cord-286950-j7m69833 34 13 , , , cord-286950-j7m69833 34 14 and and CC cord-286950-j7m69833 34 15 those those DT cord-286950-j7m69833 34 16 details detail NNS cord-286950-j7m69833 34 17 will will MD cord-286950-j7m69833 34 18 not not RB cord-286950-j7m69833 34 19 be be VB cord-286950-j7m69833 34 20 recounted recount VBN cord-286950-j7m69833 34 21 here here RB cord-286950-j7m69833 34 22 [ [ -LRB- cord-286950-j7m69833 34 23 7 7 CD cord-286950-j7m69833 34 24 , , , cord-286950-j7m69833 34 25 8 8 CD cord-286950-j7m69833 34 26 ] ] -RRB- cord-286950-j7m69833 34 27 . . . cord-286950-j7m69833 35 1 Instead instead RB cord-286950-j7m69833 35 2 , , , cord-286950-j7m69833 35 3 our -PRON- PRP$ cord-286950-j7m69833 35 4 focus focus NN cord-286950-j7m69833 35 5 will will MD cord-286950-j7m69833 35 6 be be VB cord-286950-j7m69833 35 7 to to TO cord-286950-j7m69833 35 8 make make VB cord-286950-j7m69833 35 9 the the DT cord-286950-j7m69833 35 10 case case NN cord-286950-j7m69833 35 11 for for IN cord-286950-j7m69833 35 12 the the DT cord-286950-j7m69833 35 13 scientific scientific JJ cord-286950-j7m69833 35 14 and and CC cord-286950-j7m69833 35 15 moral moral JJ cord-286950-j7m69833 35 16 value value NN cord-286950-j7m69833 35 17 of of IN cord-286950-j7m69833 35 18 GOF GOF NNP cord-286950-j7m69833 35 19 - - HYPH cord-286950-j7m69833 35 20 type type NN cord-286950-j7m69833 35 21 research research NN cord-286950-j7m69833 35 22 provided provide VBD cord-286950-j7m69833 35 23 that that IN cord-286950-j7m69833 35 24 it -PRON- PRP cord-286950-j7m69833 35 25 can can MD cord-286950-j7m69833 35 26 be be VB cord-286950-j7m69833 35 27 conducted conduct VBN cord-286950-j7m69833 35 28 safely safely RB cord-286950-j7m69833 35 29 . . . cord-286950-j7m69833 36 1 Hence hence RB cord-286950-j7m69833 36 2 , , , cord-286950-j7m69833 36 3 the the DT cord-286950-j7m69833 36 4 second second JJ cord-286950-j7m69833 36 5 round round NN cord-286950-j7m69833 36 6 of of IN cord-286950-j7m69833 36 7 the the DT cord-286950-j7m69833 36 8 controversy controversy NN cord-286950-j7m69833 36 9 was be VBD cord-286950-j7m69833 36 10 focused focus VBN cord-286950-j7m69833 36 11 less less RBR cord-286950-j7m69833 36 12 on on IN cord-286950-j7m69833 36 13 biosecurity biosecurity NN cord-286950-j7m69833 36 14 and and CC cord-286950-j7m69833 36 15 intentional intentional JJ cord-286950-j7m69833 36 16 release release NN cord-286950-j7m69833 36 17 and and CC cord-286950-j7m69833 36 18 almost almost RB cord-286950-j7m69833 36 19 entirely entirely RB cord-286950-j7m69833 36 20 on on IN cord-286950-j7m69833 36 21 biosafety biosafety NN cord-286950-j7m69833 36 22 . . . cord-286950-j7m69833 37 1 We -PRON- PRP cord-286950-j7m69833 37 2 have have VBP cord-286950-j7m69833 37 3 previously previously RB cord-286950-j7m69833 37 4 argued argue VBN cord-286950-j7m69833 37 5 that that IN cord-286950-j7m69833 37 6 the the DT cord-286950-j7m69833 37 7 H5N1 H5N1 NNP cord-286950-j7m69833 37 8 experiments experiment NNS cord-286950-j7m69833 37 9 , , , cord-286950-j7m69833 37 10 and and CC cord-286950-j7m69833 37 11 similar similar JJ cord-286950-j7m69833 37 12 GOF GOF NNP cord-286950-j7m69833 37 13 studies study NNS cord-286950-j7m69833 37 14 , , , cord-286950-j7m69833 37 15 provide provide VB cord-286950-j7m69833 37 16 benefits benefit NNS cord-286950-j7m69833 37 17 at at IN cord-286950-j7m69833 37 18 many many JJ cord-286950-j7m69833 37 19 levels level NNS cord-286950-j7m69833 37 20 , , , cord-286950-j7m69833 37 21 from from IN cord-286950-j7m69833 37 22 the the DT cord-286950-j7m69833 37 23 practical practical JJ cord-286950-j7m69833 37 24 to to IN cord-286950-j7m69833 37 25 the the DT cord-286950-j7m69833 37 26 epistemological epistemological JJ cord-286950-j7m69833 37 27 [ [ -LRB- cord-286950-j7m69833 37 28 9 9 CD cord-286950-j7m69833 37 29 , , , cord-286950-j7m69833 37 30 10 10 CD cord-286950-j7m69833 37 31 ] ] -RRB- cord-286950-j7m69833 37 32 . . . cord-286950-j7m69833 38 1 Some some DT cord-286950-j7m69833 38 2 tangible tangible JJ cord-286950-j7m69833 38 3 benefits benefit NNS cord-286950-j7m69833 38 4 of of IN cord-286950-j7m69833 38 5 GOF GOF NNP cord-286950-j7m69833 38 6 studies study NNS cord-286950-j7m69833 38 7 involving involve VBG cord-286950-j7m69833 38 8 influenza influenza NN cord-286950-j7m69833 38 9 virus virus NN cord-286950-j7m69833 38 10 include include VBP cord-286950-j7m69833 38 11 : : : cord-286950-j7m69833 38 12 [ [ -LRB- cord-286950-j7m69833 38 13 11 11 CD cord-286950-j7m69833 38 14 ] ] -RRB- cord-286950-j7m69833 38 15 , , , cord-286950-j7m69833 38 16 extending extend VBG cord-286950-j7m69833 38 17 the the DT cord-286950-j7m69833 38 18 threat threat NN cord-286950-j7m69833 38 19 horizon horizon NN cord-286950-j7m69833 38 20 to to IN cord-286950-j7m69833 38 21 H7 H7 NNP cord-286950-j7m69833 38 22 viruses virus NNS cord-286950-j7m69833 38 23 . . . cord-286950-j7m69833 39 1 2 2 LS cord-286950-j7m69833 39 2 . . . cord-286950-j7m69833 40 1 The the DT cord-286950-j7m69833 40 2 results result NNS cord-286950-j7m69833 40 3 of of IN cord-286950-j7m69833 40 4 GOF GOF NNP cord-286950-j7m69833 40 5 experiments experiment NNS cord-286950-j7m69833 40 6 can can MD cord-286950-j7m69833 40 7 inform inform VB cord-286950-j7m69833 40 8 on on IN cord-286950-j7m69833 40 9 important important JJ cord-286950-j7m69833 40 10 biological biological JJ cord-286950-j7m69833 40 11 questions question NNS cord-286950-j7m69833 40 12 . . . cord-286950-j7m69833 41 1 For for IN cord-286950-j7m69833 41 2 example example NN cord-286950-j7m69833 41 3 , , , cord-286950-j7m69833 41 4 GOF GOF NNP cord-286950-j7m69833 41 5 experiments experiment NNS cord-286950-j7m69833 41 6 yielded yield VBD cord-286950-j7m69833 41 7 mutants mutant NNS cord-286950-j7m69833 41 8 that that IN cord-286950-j7m69833 41 9 when when WRB cord-286950-j7m69833 41 10 analyzed analyze VBN cord-286950-j7m69833 41 11 showed show VBD cord-286950-j7m69833 41 12 that that IN cord-286950-j7m69833 41 13 higher high JJR cord-286950-j7m69833 41 14 and and CC cord-286950-j7m69833 41 15 lower low JJR cord-286950-j7m69833 41 16 pH pH NNP cord-286950-j7m69833 41 17 optima optima NNP cord-286950-j7m69833 41 18 for for IN cord-286950-j7m69833 41 19 the the DT cord-286950-j7m69833 41 20 hemagglutinin hemagglutinin NN cord-286950-j7m69833 41 21 were be VBD cord-286950-j7m69833 41 22 associated associate VBN cord-286950-j7m69833 41 23 with with IN cord-286950-j7m69833 41 24 enhanced enhanced JJ cord-286950-j7m69833 41 25 virulence virulence NN cord-286950-j7m69833 41 26 in in IN cord-286950-j7m69833 41 27 birds bird NNS cord-286950-j7m69833 41 28 and and CC cord-286950-j7m69833 41 29 mammals mammal NNS cord-286950-j7m69833 41 30 , , , cord-286950-j7m69833 41 31 respectively respectively RB cord-286950-j7m69833 41 32 [ [ -LRB- cord-286950-j7m69833 41 33 12 12 CD cord-286950-j7m69833 41 34 ] ] -RRB- cord-286950-j7m69833 41 35 . . . cord-286950-j7m69833 42 1 This this DT cord-286950-j7m69833 42 2 information information NN cord-286950-j7m69833 42 3 is be VBZ cord-286950-j7m69833 42 4 important important JJ cord-286950-j7m69833 42 5 for for IN cord-286950-j7m69833 42 6 knowing know VBG cord-286950-j7m69833 42 7 how how WRB cord-286950-j7m69833 42 8 influenza influenza NN cord-286950-j7m69833 42 9 viruses virus NNS cord-286950-j7m69833 42 10 jump jump VBP cord-286950-j7m69833 42 11 from from IN cord-286950-j7m69833 42 12 birds bird NNS cord-286950-j7m69833 42 13 to to IN cord-286950-j7m69833 42 14 humans human NNS cord-286950-j7m69833 42 15 , , , cord-286950-j7m69833 42 16 which which WDT cord-286950-j7m69833 42 17 is be VBZ cord-286950-j7m69833 42 18 a a DT cord-286950-j7m69833 42 19 critical critical JJ cord-286950-j7m69833 42 20 step step NN cord-286950-j7m69833 42 21 in in IN cord-286950-j7m69833 42 22 the the DT cord-286950-j7m69833 42 23 emergence emergence NN cord-286950-j7m69833 42 24 of of IN cord-286950-j7m69833 42 25 new new JJ cord-286950-j7m69833 42 26 pandemic pandemic NN cord-286950-j7m69833 42 27 strains strain NNS cord-286950-j7m69833 42 28 . . . cord-286950-j7m69833 43 1 3 3 LS cord-286950-j7m69833 43 2 . . . cord-286950-j7m69833 44 1 GOF GOF NNP cord-286950-j7m69833 44 2 experiments experiment NNS cord-286950-j7m69833 44 3 can can MD cord-286950-j7m69833 44 4 be be VB cord-286950-j7m69833 44 5 used use VBN cord-286950-j7m69833 44 6 to to TO cord-286950-j7m69833 44 7 produce produce VB cord-286950-j7m69833 44 8 new new JJ cord-286950-j7m69833 44 9 viral viral JJ cord-286950-j7m69833 44 10 strains strain NNS cord-286950-j7m69833 44 11 to to TO cord-286950-j7m69833 44 12 improve improve VB cord-286950-j7m69833 44 13 vaccine vaccine NN cord-286950-j7m69833 44 14 production production NN cord-286950-j7m69833 44 15 . . . cord-286950-j7m69833 45 1 One one CD cord-286950-j7m69833 45 2 of of IN cord-286950-j7m69833 45 3 the the DT cord-286950-j7m69833 45 4 hurdles hurdle NNS cord-286950-j7m69833 45 5 in in IN cord-286950-j7m69833 45 6 vaccine vaccine NN cord-286950-j7m69833 45 7 preparation preparation NN cord-286950-j7m69833 45 8 is be VBZ cord-286950-j7m69833 45 9 the the DT cord-286950-j7m69833 45 10 adaptation adaptation NN cord-286950-j7m69833 45 11 and and CC cord-286950-j7m69833 45 12 growth growth NN cord-286950-j7m69833 45 13 of of IN cord-286950-j7m69833 45 14 vaccination vaccination NN cord-286950-j7m69833 45 15 strains strain NNS cord-286950-j7m69833 45 16 in in IN cord-286950-j7m69833 45 17 eggs egg NNS cord-286950-j7m69833 45 18 for for IN cord-286950-j7m69833 45 19 efficient efficient JJ cord-286950-j7m69833 45 20 production production NN cord-286950-j7m69833 45 21 . . . cord-286950-j7m69833 46 1 GOF GOF NNP cord-286950-j7m69833 46 2 - - HYPH cord-286950-j7m69833 46 3 type type NN cord-286950-j7m69833 46 4 of of IN cord-286950-j7m69833 46 5 experiments experiment NNS cord-286950-j7m69833 46 6 can can MD cord-286950-j7m69833 46 7 be be VB cord-286950-j7m69833 46 8 used use VBN cord-286950-j7m69833 46 9 to to TO cord-286950-j7m69833 46 10 identify identify VB cord-286950-j7m69833 46 11 mutations mutation NNS cord-286950-j7m69833 46 12 that that WDT cord-286950-j7m69833 46 13 facilitate facilitate VBP cord-286950-j7m69833 46 14 replication replication NN cord-286950-j7m69833 46 15 of of IN cord-286950-j7m69833 46 16 influenza influenza NN cord-286950-j7m69833 46 17 strains strain NNS cord-286950-j7m69833 46 18 in in IN cord-286950-j7m69833 46 19 eggs egg NNS cord-286950-j7m69833 46 20 , , , cord-286950-j7m69833 46 21 and and CC cord-286950-j7m69833 46 22 this this DT cord-286950-j7m69833 46 23 information information NN cord-286950-j7m69833 46 24 could could MD cord-286950-j7m69833 46 25 facilitate facilitate VB cord-286950-j7m69833 46 26 vaccine vaccine NN cord-286950-j7m69833 46 27 production production NN cord-286950-j7m69833 46 28 [ [ -LRB- cord-286950-j7m69833 46 29 13 13 CD cord-286950-j7m69833 46 30 ] ] -RRB- cord-286950-j7m69833 46 31 . . . cord-286950-j7m69833 47 1 Are be VBP cord-286950-j7m69833 47 2 there there EX cord-286950-j7m69833 47 3 other other JJ cord-286950-j7m69833 47 4 claimed claim VBN cord-286950-j7m69833 47 5 benefits benefit NNS cord-286950-j7m69833 47 6 that that WDT cord-286950-j7m69833 47 7 have have VBP cord-286950-j7m69833 47 8 been be VBN cord-286950-j7m69833 47 9 derived derive VBN cord-286950-j7m69833 47 10 from from IN cord-286950-j7m69833 47 11 the the DT cord-286950-j7m69833 47 12 H5N1 H5N1 NNP cord-286950-j7m69833 47 13 studies study NNS cord-286950-j7m69833 47 14 ? ? . cord-286950-j7m69833 48 1 At at IN cord-286950-j7m69833 48 2 the the DT cord-286950-j7m69833 48 3 time time NN cord-286950-j7m69833 48 4 of of IN cord-286950-j7m69833 48 5 publication publication NN cord-286950-j7m69833 48 6 , , , cord-286950-j7m69833 48 7 the the DT cord-286950-j7m69833 48 8 authors author NNS cord-286950-j7m69833 48 9 and and CC cord-286950-j7m69833 48 10 others other NNS cord-286950-j7m69833 48 11 argued argue VBD cord-286950-j7m69833 48 12 that that IN cord-286950-j7m69833 48 13 the the DT cord-286950-j7m69833 48 14 results result NNS cord-286950-j7m69833 48 15 would would MD cord-286950-j7m69833 48 16 inform inform VB cord-286950-j7m69833 48 17 surveillance surveillance NN cord-286950-j7m69833 48 18 efforts effort NNS cord-286950-j7m69833 48 19 and and CC cord-286950-j7m69833 48 20 vaccine vaccine NN cord-286950-j7m69833 48 21 development development NN cord-286950-j7m69833 48 22 . . . cord-286950-j7m69833 49 1 It -PRON- PRP cord-286950-j7m69833 49 2 is be VBZ cord-286950-j7m69833 49 3 unclear unclear JJ cord-286950-j7m69833 49 4 to to IN cord-286950-j7m69833 49 5 us -PRON- PRP cord-286950-j7m69833 49 6 how how WRB cord-286950-j7m69833 49 7 much much JJ cord-286950-j7m69833 49 8 surveillance surveillance NN cord-286950-j7m69833 49 9 has have VBZ cord-286950-j7m69833 49 10 benefitted benefit VBN cord-286950-j7m69833 49 11 although although IN cord-286950-j7m69833 49 12 the the DT cord-286950-j7m69833 49 13 mutation mutation NN cord-286950-j7m69833 49 14 information information NN cord-286950-j7m69833 49 15 has have VBZ cord-286950-j7m69833 49 16 been be VBN cord-286950-j7m69833 49 17 used use VBN cord-286950-j7m69833 49 18 in in IN cord-286950-j7m69833 49 19 monitoring monitor VBG cord-286950-j7m69833 49 20 [ [ -LRB- cord-286950-j7m69833 49 21 14 14 CD cord-286950-j7m69833 49 22 , , , cord-286950-j7m69833 49 23 15 15 CD cord-286950-j7m69833 49 24 ] ] -RRB- cord-286950-j7m69833 49 25 . . . cord-286950-j7m69833 50 1 As as IN cord-286950-j7m69833 50 2 we -PRON- PRP cord-286950-j7m69833 50 3 and and CC cord-286950-j7m69833 50 4 others other NNS cord-286950-j7m69833 50 5 have have VBP cord-286950-j7m69833 50 6 pointed point VBN cord-286950-j7m69833 50 7 out out RP cord-286950-j7m69833 50 8 , , , cord-286950-j7m69833 50 9 there there EX cord-286950-j7m69833 50 10 is be VBZ cord-286950-j7m69833 50 11 a a DT cord-286950-j7m69833 50 12 danger danger NN cord-286950-j7m69833 50 13 of of IN cord-286950-j7m69833 50 14 focusing focus VBG cord-286950-j7m69833 50 15 on on IN cord-286950-j7m69833 50 16 the the DT cord-286950-j7m69833 50 17 exact exact JJ cord-286950-j7m69833 50 18 mutations mutation NNS cord-286950-j7m69833 50 19 discovered discover VBN cord-286950-j7m69833 50 20 in in IN cord-286950-j7m69833 50 21 the the DT cord-286950-j7m69833 50 22 ferret ferret JJ cord-286950-j7m69833 50 23 experiments experiment NNS cord-286950-j7m69833 50 24 because because IN cord-286950-j7m69833 50 25 there there EX cord-286950-j7m69833 50 26 may may MD cord-286950-j7m69833 50 27 be be VB cord-286950-j7m69833 50 28 other other JJ cord-286950-j7m69833 50 29 genetic genetic JJ cord-286950-j7m69833 50 30 routes route NNS cord-286950-j7m69833 50 31 to to IN cord-286950-j7m69833 50 32 human human JJ cord-286950-j7m69833 50 33 transmissibility transmissibility NN cord-286950-j7m69833 50 34 [ [ -LRB- cord-286950-j7m69833 50 35 10 10 CD cord-286950-j7m69833 50 36 ] ] -RRB- cord-286950-j7m69833 50 37 . . . cord-286950-j7m69833 51 1 Some some DT cord-286950-j7m69833 51 2 have have VBP cord-286950-j7m69833 51 3 noted note VBN cord-286950-j7m69833 51 4 that that IN cord-286950-j7m69833 51 5 by by IN cord-286950-j7m69833 51 6 the the DT cord-286950-j7m69833 51 7 time time NN cord-286950-j7m69833 51 8 such such JJ cord-286950-j7m69833 51 9 mutations mutation NNS cord-286950-j7m69833 51 10 have have VBP cord-286950-j7m69833 51 11 been be VBN cord-286950-j7m69833 51 12 detected detect VBN cord-286950-j7m69833 51 13 in in IN cord-286950-j7m69833 51 14 avian avian JJ cord-286950-j7m69833 51 15 populations population NNS cord-286950-j7m69833 51 16 , , , cord-286950-j7m69833 51 17 it -PRON- PRP cord-286950-j7m69833 51 18 might may MD cord-286950-j7m69833 51 19 be be VB cord-286950-j7m69833 51 20 too too RB cord-286950-j7m69833 51 21 late late JJ cord-286950-j7m69833 51 22 to to TO cord-286950-j7m69833 51 23 stop stop VB cord-286950-j7m69833 51 24 the the DT cord-286950-j7m69833 51 25 spread spread NN cord-286950-j7m69833 51 26 due due IN cord-286950-j7m69833 51 27 to to IN cord-286950-j7m69833 51 28 the the DT cord-286950-j7m69833 51 29 relative relative JJ cord-286950-j7m69833 51 30 rates rate NNS cord-286950-j7m69833 51 31 with with IN cord-286950-j7m69833 51 32 which which WDT cord-286950-j7m69833 51 33 we -PRON- PRP cord-286950-j7m69833 51 34 can can MD cord-286950-j7m69833 51 35 identify identify VB cord-286950-j7m69833 51 36 those those DT cord-286950-j7m69833 51 37 mutations mutation NNS cord-286950-j7m69833 51 38 using use VBG cord-286950-j7m69833 51 39 current current JJ cord-286950-j7m69833 51 40 technology technology NN cord-286950-j7m69833 51 41 and and CC cord-286950-j7m69833 51 42 the the DT cord-286950-j7m69833 51 43 rate rate NN cord-286950-j7m69833 51 44 of of IN cord-286950-j7m69833 51 45 spread spread NN cord-286950-j7m69833 51 46 of of IN cord-286950-j7m69833 51 47 influenza influenza NN cord-286950-j7m69833 51 48 virus virus NN cord-286950-j7m69833 51 49 [ [ -LRB- cord-286950-j7m69833 51 50 16 16 CD cord-286950-j7m69833 51 51 , , , cord-286950-j7m69833 51 52 17 17 CD cord-286950-j7m69833 51 53 ] ] -RRB- cord-286950-j7m69833 51 54 . . . cord-286950-j7m69833 52 1 Increased increase VBN cord-286950-j7m69833 52 2 awareness awareness NN cord-286950-j7m69833 52 3 of of IN cord-286950-j7m69833 52 4 the the DT cord-286950-j7m69833 52 5 threat threat NN cord-286950-j7m69833 52 6 of of IN cord-286950-j7m69833 52 7 H5N1 H5N1 NNP cord-286950-j7m69833 52 8 , , , cord-286950-j7m69833 52 9 however however RB cord-286950-j7m69833 52 10 , , , cord-286950-j7m69833 52 11 must must MD cord-286950-j7m69833 52 12 certainly certainly RB cord-286950-j7m69833 52 13 have have VB cord-286950-j7m69833 52 14 led lead VBN cord-286950-j7m69833 52 15 to to IN cord-286950-j7m69833 52 16 better well JJR cord-286950-j7m69833 52 17 isolation isolation NN cord-286950-j7m69833 52 18 of of IN cord-286950-j7m69833 52 19 patients patient NNS cord-286950-j7m69833 52 20 who who WP cord-286950-j7m69833 52 21 have have VBP cord-286950-j7m69833 52 22 been be VBN cord-286950-j7m69833 52 23 exposed expose VBN cord-286950-j7m69833 52 24 to to IN cord-286950-j7m69833 52 25 the the DT cord-286950-j7m69833 52 26 virus virus NN cord-286950-j7m69833 52 27 . . . cord-286950-j7m69833 53 1 In in IN cord-286950-j7m69833 53 2 this this DT cord-286950-j7m69833 53 3 regard regard NN cord-286950-j7m69833 53 4 , , , cord-286950-j7m69833 53 5 it -PRON- PRP cord-286950-j7m69833 53 6 seems seem VBZ cord-286950-j7m69833 53 7 reasonable reasonable JJ cord-286950-j7m69833 53 8 to to TO cord-286950-j7m69833 53 9 assume assume VB cord-286950-j7m69833 53 10 that that IN cord-286950-j7m69833 53 11 any any DT cord-286950-j7m69833 53 12 onward onward JJ cord-286950-j7m69833 53 13 transmission transmission NN cord-286950-j7m69833 53 14 of of IN cord-286950-j7m69833 53 15 an an DT cord-286950-j7m69833 53 16 avian avian JJ cord-286950-j7m69833 53 17 strain strain NN cord-286950-j7m69833 53 18 would would MD cord-286950-j7m69833 53 19 occur occur VB cord-286950-j7m69833 53 20 largely largely RB cord-286950-j7m69833 53 21 in in IN cord-286950-j7m69833 53 22 the the DT cord-286950-j7m69833 53 23 healthcare healthcare NN cord-286950-j7m69833 53 24 setting setting NN cord-286950-j7m69833 53 25 , , , cord-286950-j7m69833 53 26 as as IN cord-286950-j7m69833 53 27 has have VBZ cord-286950-j7m69833 53 28 been be VBN cord-286950-j7m69833 53 29 the the DT cord-286950-j7m69833 53 30 case case NN cord-286950-j7m69833 53 31 with with IN cord-286950-j7m69833 53 32 SARS SARS NNP cord-286950-j7m69833 53 33 - - HYPH cord-286950-j7m69833 53 34 CoV CoV NNP cord-286950-j7m69833 53 35 and and CC cord-286950-j7m69833 53 36 MERS MERS NNP cord-286950-j7m69833 53 37 - - HYPH cord-286950-j7m69833 53 38 CoV CoV NNP cord-286950-j7m69833 53 39 , , , cord-286950-j7m69833 53 40 and and CC cord-286950-j7m69833 53 41 rapid rapid JJ cord-286950-j7m69833 53 42 intervention intervention NN cord-286950-j7m69833 53 43 could could MD cord-286950-j7m69833 53 44 prevent prevent VB cord-286950-j7m69833 53 45 a a DT cord-286950-j7m69833 53 46 widespread widespread JJ cord-286950-j7m69833 53 47 outbreak outbreak NN cord-286950-j7m69833 53 48 . . . cord-286950-j7m69833 54 1 While while IN cord-286950-j7m69833 54 2 monitoring monitor VBG cord-286950-j7m69833 54 3 the the DT cord-286950-j7m69833 54 4 mutations mutation NNS cord-286950-j7m69833 54 5 discovered discover VBN cord-286950-j7m69833 54 6 in in IN cord-286950-j7m69833 54 7 the the DT cord-286950-j7m69833 54 8 laboratory laboratory NN cord-286950-j7m69833 54 9 from from IN cord-286950-j7m69833 54 10 GOF GOF NNP cord-286950-j7m69833 54 11 experiments experiment NNS cord-286950-j7m69833 54 12 is be VBZ cord-286950-j7m69833 54 13 not not RB cord-286950-j7m69833 54 14 sufficient sufficient JJ cord-286950-j7m69833 54 15 to to TO cord-286950-j7m69833 54 16 predict predict VB cord-286950-j7m69833 54 17 dangers danger NNS cord-286950-j7m69833 54 18 from from IN cord-286950-j7m69833 54 19 environmental environmental JJ cord-286950-j7m69833 54 20 isolates isolate NNS cord-286950-j7m69833 54 21 , , , cord-286950-j7m69833 54 22 it -PRON- PRP cord-286950-j7m69833 54 23 is be VBZ cord-286950-j7m69833 54 24 important important JJ cord-286950-j7m69833 54 25 to to TO cord-286950-j7m69833 54 26 note note VB cord-286950-j7m69833 54 27 that that IN cord-286950-j7m69833 54 28 while while IN cord-286950-j7m69833 54 29 both both DT cord-286950-j7m69833 54 30 groups group NNS cord-286950-j7m69833 54 31 obtained obtain VBD cord-286950-j7m69833 54 32 viruses virus NNS cord-286950-j7m69833 54 33 with with IN cord-286950-j7m69833 54 34 different different JJ cord-286950-j7m69833 54 35 mutations mutation NNS cord-286950-j7m69833 54 36 , , , cord-286950-j7m69833 54 37 they -PRON- PRP cord-286950-j7m69833 54 38 both both DT cord-286950-j7m69833 54 39 achieved achieve VBD cord-286950-j7m69833 54 40 similar similar JJ cord-286950-j7m69833 54 41 phenotypes phenotype NNS cord-286950-j7m69833 54 42 of of IN cord-286950-j7m69833 54 43 enhanced enhanced JJ cord-286950-j7m69833 54 44 stability stability NN cord-286950-j7m69833 54 45 of of IN cord-286950-j7m69833 54 46 the the DT cord-286950-j7m69833 54 47 HA HA NNP cord-286950-j7m69833 54 48 protein protein NN cord-286950-j7m69833 54 49 . . . cord-286950-j7m69833 55 1 As as IN cord-286950-j7m69833 55 2 our -PRON- PRP$ cord-286950-j7m69833 55 3 ability ability NN cord-286950-j7m69833 55 4 to to TO cord-286950-j7m69833 55 5 predict predict VB cord-286950-j7m69833 55 6 phenotype phenotype NN cord-286950-j7m69833 55 7 from from IN cord-286950-j7m69833 55 8 genotype genotype NN cord-286950-j7m69833 55 9 improves improve VBZ cord-286950-j7m69833 55 10 , , , cord-286950-j7m69833 55 11 this this DT cord-286950-j7m69833 55 12 becomes become VBZ cord-286950-j7m69833 55 13 increasingly increasingly RB cord-286950-j7m69833 55 14 important important JJ cord-286950-j7m69833 55 15 . . . cord-286950-j7m69833 56 1 A a DT cord-286950-j7m69833 56 2 big big JJ cord-286950-j7m69833 56 3 caveat caveat NN cord-286950-j7m69833 56 4 to to IN cord-286950-j7m69833 56 5 overstating overstate VBG cord-286950-j7m69833 56 6 the the DT cord-286950-j7m69833 56 7 importance importance NN cord-286950-j7m69833 56 8 of of IN cord-286950-j7m69833 56 9 this this DT cord-286950-j7m69833 56 10 , , , cord-286950-j7m69833 56 11 however however RB cord-286950-j7m69833 56 12 , , , cord-286950-j7m69833 56 13 is be VBZ cord-286950-j7m69833 56 14 the the DT cord-286950-j7m69833 56 15 contribution contribution NN cord-286950-j7m69833 56 16 of of IN cord-286950-j7m69833 56 17 epistasis epistasis NN cord-286950-j7m69833 56 18 to to IN cord-286950-j7m69833 56 19 any any DT cord-286950-j7m69833 56 20 given give VBN cord-286950-j7m69833 56 21 phenotype phenotype NN cord-286950-j7m69833 56 22 . . . cord-286950-j7m69833 57 1 For for IN cord-286950-j7m69833 57 2 example example NN cord-286950-j7m69833 57 3 , , , cord-286950-j7m69833 57 4 the the DT cord-286950-j7m69833 57 5 same same JJ cord-286950-j7m69833 57 6 mutations mutation NNS cord-286950-j7m69833 57 7 identified identify VBN cord-286950-j7m69833 57 8 by by IN cord-286950-j7m69833 57 9 the the DT cord-286950-j7m69833 57 10 Fouchier Fouchier NNP cord-286950-j7m69833 57 11 group group NN cord-286950-j7m69833 57 12 , , , cord-286950-j7m69833 57 13 when when WRB cord-286950-j7m69833 57 14 introduced introduce VBN cord-286950-j7m69833 57 15 into into IN cord-286950-j7m69833 57 16 a a DT cord-286950-j7m69833 57 17 different different JJ cord-286950-j7m69833 57 18 H5N1 H5N1 NNP cord-286950-j7m69833 57 19 background background NN cord-286950-j7m69833 57 20 , , , cord-286950-j7m69833 57 21 yielded yield VBD cord-286950-j7m69833 57 22 a a DT cord-286950-j7m69833 57 23 different different JJ cord-286950-j7m69833 57 24 HA HA NNP cord-286950-j7m69833 57 25 phenotype phenotype NN cord-286950-j7m69833 57 26 [ [ -LRB- cord-286950-j7m69833 57 27 18 18 CD cord-286950-j7m69833 57 28 ] ] -RRB- cord-286950-j7m69833 57 29 . . . cord-286950-j7m69833 58 1 This this DT cord-286950-j7m69833 58 2 implies imply VBZ cord-286950-j7m69833 58 3 that that IN cord-286950-j7m69833 58 4 insights insight NNS cord-286950-j7m69833 58 5 gained gain VBD cord-286950-j7m69833 58 6 from from IN cord-286950-j7m69833 58 7 one one CD cord-286950-j7m69833 58 8 set set NN cord-286950-j7m69833 58 9 of of IN cord-286950-j7m69833 58 10 mutations mutation NNS cord-286950-j7m69833 58 11 in in IN cord-286950-j7m69833 58 12 one one CD cord-286950-j7m69833 58 13 strain strain NN cord-286950-j7m69833 58 14 are be VBP cord-286950-j7m69833 58 15 unlikely unlikely JJ cord-286950-j7m69833 58 16 to to TO cord-286950-j7m69833 58 17 be be VB cord-286950-j7m69833 58 18 generalizable generalizable JJ cord-286950-j7m69833 58 19 to to IN cord-286950-j7m69833 58 20 other other JJ cord-286950-j7m69833 58 21 strains strain NNS cord-286950-j7m69833 58 22 given give VBN cord-286950-j7m69833 58 23 sequence sequence NN cord-286950-j7m69833 58 24 differences difference NNS cord-286950-j7m69833 58 25 . . . cord-286950-j7m69833 59 1 Hence hence RB cord-286950-j7m69833 59 2 , , , cord-286950-j7m69833 59 3 with with IN cord-286950-j7m69833 59 4 the the DT cord-286950-j7m69833 59 5 hindsight hindsight NN cord-286950-j7m69833 59 6 of of IN cord-286950-j7m69833 59 7 half half PDT cord-286950-j7m69833 59 8 a a DT cord-286950-j7m69833 59 9 decade decade NN cord-286950-j7m69833 59 10 of of IN cord-286950-j7m69833 59 11 work work NN cord-286950-j7m69833 59 12 since since IN cord-286950-j7m69833 59 13 the the DT cord-286950-j7m69833 59 14 original original JJ cord-286950-j7m69833 59 15 controversy controversy NN cord-286950-j7m69833 59 16 in in IN cord-286950-j7m69833 59 17 2012 2012 CD cord-286950-j7m69833 59 18 , , , cord-286950-j7m69833 59 19 it -PRON- PRP cord-286950-j7m69833 59 20 appears appear VBZ cord-286950-j7m69833 59 21 that that IN cord-286950-j7m69833 59 22 GOF GOF NNP cord-286950-j7m69833 59 23 - - HYPH cord-286950-j7m69833 59 24 type type NN cord-286950-j7m69833 59 25 experiments experiment NNS cord-286950-j7m69833 59 26 are be VBP cord-286950-j7m69833 59 27 very very RB cord-286950-j7m69833 59 28 informative informative JJ cord-286950-j7m69833 59 29 with with IN cord-286950-j7m69833 59 30 regard regard NN cord-286950-j7m69833 59 31 to to IN cord-286950-j7m69833 59 32 big big JJ cord-286950-j7m69833 59 33 questions question NNS cord-286950-j7m69833 59 34 such such JJ cord-286950-j7m69833 59 35 as as IN cord-286950-j7m69833 59 36 whether whether IN cord-286950-j7m69833 59 37 mammalian mammalian JJ cord-286950-j7m69833 59 38 virulence virulence NN cord-286950-j7m69833 59 39 and and CC cord-286950-j7m69833 59 40 transmissibility transmissibility NN cord-286950-j7m69833 59 41 potential potential NN cord-286950-j7m69833 59 42 exists exist VBZ cord-286950-j7m69833 59 43 in in IN cord-286950-j7m69833 59 44 HPAIV HPAIV NNP cord-286950-j7m69833 59 45 but but CC cord-286950-j7m69833 59 46 may may MD cord-286950-j7m69833 59 47 be be VB cord-286950-j7m69833 59 48 less less RBR cord-286950-j7m69833 59 49 useful useful JJ cord-286950-j7m69833 59 50 in in IN cord-286950-j7m69833 59 51 making make VBG cord-286950-j7m69833 59 52 fine fine JJ cord-286950-j7m69833 59 53 - - HYPH cord-286950-j7m69833 59 54 scale scale NN cord-286950-j7m69833 59 55 molecular molecular JJ cord-286950-j7m69833 59 56 predictions prediction NNS cord-286950-j7m69833 59 57 . . . cord-286950-j7m69833 60 1 As as IN cord-286950-j7m69833 60 2 mentioned mention VBN cord-286950-j7m69833 60 3 above above RB cord-286950-j7m69833 60 4 , , , cord-286950-j7m69833 60 5 in in IN cord-286950-j7m69833 60 6 2014 2014 CD cord-286950-j7m69833 60 7 the the DT cord-286950-j7m69833 60 8 US US NNP cord-286950-j7m69833 60 9 government government NN cord-286950-j7m69833 60 10 mandated mandate VBD cord-286950-j7m69833 60 11 a a DT cord-286950-j7m69833 60 12 moratorium moratorium NN cord-286950-j7m69833 60 13 on on IN cord-286950-j7m69833 60 14 GOF GOF NNP cord-286950-j7m69833 60 15 - - HYPH cord-286950-j7m69833 60 16 type type NN cord-286950-j7m69833 60 17 experiments experiment NNS cord-286950-j7m69833 60 18 involving involve VBG cord-286950-j7m69833 60 19 PPP PPP NNP cord-286950-j7m69833 60 20 such such JJ cord-286950-j7m69833 60 21 as as IN cord-286950-j7m69833 60 22 influenza influenza NN cord-286950-j7m69833 60 23 , , , cord-286950-j7m69833 60 24 MERS MERS NNP cord-286950-j7m69833 60 25 - - HYPH cord-286950-j7m69833 60 26 CoV CoV NNP cord-286950-j7m69833 60 27 , , , cord-286950-j7m69833 60 28 and and CC cord-286950-j7m69833 60 29 SARS SARS NNP cord-286950-j7m69833 60 30 - - HYPH cord-286950-j7m69833 60 31 CoV. CoV. NNP cord-286950-j7m69833 61 1 To to IN cord-286950-j7m69833 61 2 the the DT cord-286950-j7m69833 61 3 best good JJS cord-286950-j7m69833 61 4 of of IN cord-286950-j7m69833 61 5 our -PRON- PRP$ cord-286950-j7m69833 61 6 knowledge knowledge NN cord-286950-j7m69833 61 7 , , , cord-286950-j7m69833 61 8 US US NNP cord-286950-j7m69833 61 9 - - HYPH cord-286950-j7m69833 61 10 supported support VBN cord-286950-j7m69833 61 11 experiments experiment NNS cord-286950-j7m69833 61 12 to to TO cord-286950-j7m69833 61 13 examine examine VB cord-286950-j7m69833 61 14 changes change NNS cord-286950-j7m69833 61 15 in in IN cord-286950-j7m69833 61 16 transmission transmission NN cord-286950-j7m69833 61 17 of of IN cord-286950-j7m69833 61 18 avian avian JJ cord-286950-j7m69833 61 19 influenza influenza NN cord-286950-j7m69833 61 20 viruses virus NNS cord-286950-j7m69833 61 21 have have VBP cord-286950-j7m69833 61 22 largely largely RB cord-286950-j7m69833 61 23 stopped stop VBN cord-286950-j7m69833 61 24 . . . cord-286950-j7m69833 62 1 The the DT cord-286950-j7m69833 62 2 Fouchier Fouchier NNP cord-286950-j7m69833 62 3 lab lab NN cord-286950-j7m69833 62 4 did do VBD cord-286950-j7m69833 62 5 publish publish VB cord-286950-j7m69833 62 6 a a DT cord-286950-j7m69833 62 7 follow follow NN cord-286950-j7m69833 62 8 - - HYPH cord-286950-j7m69833 62 9 up up NN cord-286950-j7m69833 62 10 report report NN cord-286950-j7m69833 62 11 to to IN cord-286950-j7m69833 62 12 their -PRON- PRP$ cord-286950-j7m69833 62 13 original original JJ cord-286950-j7m69833 62 14 Science Science NNP cord-286950-j7m69833 62 15 manuscript manuscript NN cord-286950-j7m69833 62 16 in in IN cord-286950-j7m69833 62 17 which which WDT cord-286950-j7m69833 62 18 they -PRON- PRP cord-286950-j7m69833 62 19 narrowed narrow VBD cord-286950-j7m69833 62 20 down down IN cord-286950-j7m69833 62 21 the the DT cord-286950-j7m69833 62 22 exact exact JJ cord-286950-j7m69833 62 23 mutations mutation NNS cord-286950-j7m69833 62 24 that that WDT cord-286950-j7m69833 62 25 enabled enable VBD cord-286950-j7m69833 62 26 transmission transmission NN cord-286950-j7m69833 62 27 in in IN cord-286950-j7m69833 62 28 the the DT cord-286950-j7m69833 62 29 ferret ferret NN cord-286950-j7m69833 62 30 model model NN cord-286950-j7m69833 62 31 , , , cord-286950-j7m69833 62 32 but but CC cord-286950-j7m69833 62 33 based base VBN cord-286950-j7m69833 62 34 on on IN cord-286950-j7m69833 62 35 the the DT cord-286950-j7m69833 62 36 publication publication NN cord-286950-j7m69833 62 37 date date NN cord-286950-j7m69833 62 38 , , , cord-286950-j7m69833 62 39 it -PRON- PRP cord-286950-j7m69833 62 40 appears appear VBZ cord-286950-j7m69833 62 41 that that IN cord-286950-j7m69833 62 42 this this DT cord-286950-j7m69833 62 43 work work NN cord-286950-j7m69833 62 44 was be VBD cord-286950-j7m69833 62 45 completed complete VBN cord-286950-j7m69833 62 46 prior prior RB cord-286950-j7m69833 62 47 to to IN cord-286950-j7m69833 62 48 the the DT cord-286950-j7m69833 62 49 moratorium moratorium NN cord-286950-j7m69833 62 50 [ [ -LRB- cord-286950-j7m69833 62 51 19 19 CD cord-286950-j7m69833 62 52 ] ] -RRB- cord-286950-j7m69833 62 53 . . . cord-286950-j7m69833 63 1 In in IN cord-286950-j7m69833 63 2 the the DT cord-286950-j7m69833 63 3 MERS MERS NNP cord-286950-j7m69833 63 4 - - HYPH cord-286950-j7m69833 63 5 CoV CoV NNP cord-286950-j7m69833 63 6 field field NN cord-286950-j7m69833 63 7 , , , cord-286950-j7m69833 63 8 the the DT cord-286950-j7m69833 63 9 development development NN cord-286950-j7m69833 63 10 of of IN cord-286950-j7m69833 63 11 a a DT cord-286950-j7m69833 63 12 small small JJ cord-286950-j7m69833 63 13 animal animal NN cord-286950-j7m69833 63 14 model model NN cord-286950-j7m69833 63 15 that that WDT cord-286950-j7m69833 63 16 faithfully faithfully RB cord-286950-j7m69833 63 17 reproduces reproduce VBZ cord-286950-j7m69833 63 18 human human JJ cord-286950-j7m69833 63 19 transmission transmission NN cord-286950-j7m69833 63 20 and and CC cord-286950-j7m69833 63 21 disease disease NN cord-286950-j7m69833 63 22 has have VBZ cord-286950-j7m69833 63 23 been be VBN cord-286950-j7m69833 63 24 slowed slow VBN cord-286950-j7m69833 63 25 significantly significantly RB cord-286950-j7m69833 63 26 by by IN cord-286950-j7m69833 63 27 the the DT cord-286950-j7m69833 63 28 moratorium moratorium NN cord-286950-j7m69833 63 29 . . . cord-286950-j7m69833 64 1 MERS MERS NNP cord-286950-j7m69833 64 2 - - HYPH cord-286950-j7m69833 64 3 CoV CoV NNP cord-286950-j7m69833 64 4 uses use VBZ cord-286950-j7m69833 64 5 the the DT cord-286950-j7m69833 64 6 dipeptidyl dipeptidyl JJ cord-286950-j7m69833 64 7 peptidase peptidase NN cord-286950-j7m69833 64 8 4 4 CD cord-286950-j7m69833 64 9 ( ( -LRB- cord-286950-j7m69833 64 10 DPP4 DPP4 NNP cord-286950-j7m69833 64 11 ) ) -RRB- cord-286950-j7m69833 64 12 protein protein NN cord-286950-j7m69833 64 13 as as IN cord-286950-j7m69833 64 14 a a DT cord-286950-j7m69833 64 15 receptor receptor NN cord-286950-j7m69833 64 16 , , , cord-286950-j7m69833 64 17 and and CC cord-286950-j7m69833 64 18 the the DT cord-286950-j7m69833 64 19 human human JJ cord-286950-j7m69833 64 20 and and CC cord-286950-j7m69833 64 21 murine murine JJ cord-286950-j7m69833 64 22 proteins protein NNS cord-286950-j7m69833 64 23 differ differ VBP cord-286950-j7m69833 64 24 enough enough RB cord-286950-j7m69833 64 25 such such JJ cord-286950-j7m69833 64 26 that that IN cord-286950-j7m69833 64 27 the the DT cord-286950-j7m69833 64 28 virus virus NN cord-286950-j7m69833 64 29 can can MD cord-286950-j7m69833 64 30 not not RB cord-286950-j7m69833 64 31 use use VB cord-286950-j7m69833 64 32 the the DT cord-286950-j7m69833 64 33 mouse mouse NN cord-286950-j7m69833 64 34 molecule molecule NN cord-286950-j7m69833 64 35 . . . cord-286950-j7m69833 65 1 Transgenic transgenic JJ cord-286950-j7m69833 65 2 mice mouse NNS cord-286950-j7m69833 65 3 that that WDT cord-286950-j7m69833 65 4 express express VBP cord-286950-j7m69833 65 5 human human JJ cord-286950-j7m69833 65 6 DPP4 DPP4 NNP cord-286950-j7m69833 65 7 ubiquitously ubiquitously RB cord-286950-j7m69833 65 8 experience experience VBP cord-286950-j7m69833 65 9 a a DT cord-286950-j7m69833 65 10 broader broad JJR cord-286950-j7m69833 65 11 set set NN cord-286950-j7m69833 65 12 of of IN cord-286950-j7m69833 65 13 symptoms symptom NNS cord-286950-j7m69833 65 14 than than IN cord-286950-j7m69833 65 15 do do VB cord-286950-j7m69833 65 16 humans human NNS cord-286950-j7m69833 65 17 when when WRB cord-286950-j7m69833 65 18 infected infect VBN cord-286950-j7m69833 65 19 with with IN cord-286950-j7m69833 65 20 wild wild JJ cord-286950-j7m69833 65 21 - - HYPH cord-286950-j7m69833 65 22 type type NN cord-286950-j7m69833 65 23 MERS MERS NNP cord-286950-j7m69833 65 24 - - HYPH cord-286950-j7m69833 65 25 CoV CoV NNP cord-286950-j7m69833 65 26 [ [ -LRB- cord-286950-j7m69833 65 27 20 20 CD cord-286950-j7m69833 65 28 ] ] -RRB- cord-286950-j7m69833 65 29 [ [ -LRB- cord-286950-j7m69833 65 30 21 21 CD cord-286950-j7m69833 65 31 ] ] -RRB- cord-286950-j7m69833 66 1 [ [ -LRB- cord-286950-j7m69833 66 2 22 22 CD cord-286950-j7m69833 66 3 ] ] -RRB- cord-286950-j7m69833 66 4 [ [ -LRB- cord-286950-j7m69833 66 5 23 23 CD cord-286950-j7m69833 66 6 ] ] -RRB- cord-286950-j7m69833 66 7 . . . cord-286950-j7m69833 67 1 This this DT cord-286950-j7m69833 67 2 problem problem NN cord-286950-j7m69833 67 3 was be VBD cord-286950-j7m69833 67 4 recently recently RB cord-286950-j7m69833 67 5 overcome overcome VBN cord-286950-j7m69833 67 6 by by IN cord-286950-j7m69833 67 7 developing develop VBG cord-286950-j7m69833 67 8 a a DT cord-286950-j7m69833 67 9 transgenic transgenic JJ cord-286950-j7m69833 67 10 mouse mouse NN cord-286950-j7m69833 67 11 expressing express VBG cord-286950-j7m69833 67 12 a a DT cord-286950-j7m69833 67 13 mutant mutant JJ cord-286950-j7m69833 67 14 DPP4 DPP4 NNP cord-286950-j7m69833 67 15 in in IN cord-286950-j7m69833 67 16 which which WDT cord-286950-j7m69833 67 17 two two CD cord-286950-j7m69833 67 18 key key JJ cord-286950-j7m69833 67 19 amino amino NN cord-286950-j7m69833 67 20 acids acid NNS cord-286950-j7m69833 67 21 were be VBD cord-286950-j7m69833 67 22 mutated mutate VBN cord-286950-j7m69833 67 23 from from IN cord-286950-j7m69833 67 24 the the DT cord-286950-j7m69833 67 25 mouse mouse NN cord-286950-j7m69833 67 26 allele allele NN cord-286950-j7m69833 67 27 to to IN cord-286950-j7m69833 67 28 the the DT cord-286950-j7m69833 67 29 human human JJ cord-286950-j7m69833 67 30 allele allele NN cord-286950-j7m69833 67 31 . . . cord-286950-j7m69833 68 1 However however RB cord-286950-j7m69833 68 2 , , , cord-286950-j7m69833 68 3 the the DT cord-286950-j7m69833 68 4 authors author NNS cord-286950-j7m69833 68 5 still still RB cord-286950-j7m69833 68 6 needed need VBD cord-286950-j7m69833 68 7 to to TO cord-286950-j7m69833 68 8 passage passage VB cord-286950-j7m69833 68 9 the the DT cord-286950-j7m69833 68 10 virus virus NN cord-286950-j7m69833 68 11 through through IN cord-286950-j7m69833 68 12 these these DT cord-286950-j7m69833 68 13 transgenic transgenic JJ cord-286950-j7m69833 68 14 mice mouse NNS cord-286950-j7m69833 68 15 to to TO cord-286950-j7m69833 68 16 derive derive VB cord-286950-j7m69833 68 17 a a DT cord-286950-j7m69833 68 18 GOF GOF NNP cord-286950-j7m69833 68 19 variant variant NN cord-286950-j7m69833 68 20 that that WDT cord-286950-j7m69833 68 21 recapitulated recapitulate VBD cord-286950-j7m69833 68 22 human human JJ cord-286950-j7m69833 68 23 disease disease NN cord-286950-j7m69833 68 24 [ [ -LRB- cord-286950-j7m69833 68 25 24 24 CD cord-286950-j7m69833 68 26 ] ] -RRB- cord-286950-j7m69833 68 27 . . . cord-286950-j7m69833 69 1 This this DT cord-286950-j7m69833 69 2 GOF GOF NNP cord-286950-j7m69833 69 3 virus virus NN cord-286950-j7m69833 69 4 was be VBD cord-286950-j7m69833 69 5 subsequently subsequently RB cord-286950-j7m69833 69 6 used use VBN cord-286950-j7m69833 69 7 to to TO cord-286950-j7m69833 69 8 show show VB cord-286950-j7m69833 69 9 the the DT cord-286950-j7m69833 69 10 efficacy efficacy NN cord-286950-j7m69833 69 11 of of IN cord-286950-j7m69833 69 12 a a DT cord-286950-j7m69833 69 13 promising promising JJ cord-286950-j7m69833 69 14 nucleotide nucleotide JJ cord-286950-j7m69833 69 15 prodrug prodrug NN cord-286950-j7m69833 69 16 , , , cord-286950-j7m69833 69 17 originally originally RB cord-286950-j7m69833 69 18 initially initially RB cord-286950-j7m69833 69 19 developed develop VBN cord-286950-j7m69833 69 20 for for IN cord-286950-j7m69833 69 21 Ebola Ebola NNP cord-286950-j7m69833 69 22 virus virus NN cord-286950-j7m69833 69 23 , , , cord-286950-j7m69833 69 24 for for IN cord-286950-j7m69833 69 25 treating treat VBG cord-286950-j7m69833 69 26 MERS MERS NNPS cord-286950-j7m69833 69 27 [ [ -LRB- cord-286950-j7m69833 69 28 25 25 CD cord-286950-j7m69833 69 29 ] ] -RRB- cord-286950-j7m69833 69 30 . . . cord-286950-j7m69833 70 1 Continuing continue VBG cord-286950-j7m69833 70 2 efforts effort NNS cord-286950-j7m69833 70 3 to to TO cord-286950-j7m69833 70 4 produce produce VB cord-286950-j7m69833 70 5 a a DT cord-286950-j7m69833 70 6 mouse mouse NN cord-286950-j7m69833 70 7 - - HYPH cord-286950-j7m69833 70 8 adapted adapt VBN cord-286950-j7m69833 70 9 MERS MERS NNP cord-286950-j7m69833 70 10 - - HYPH cord-286950-j7m69833 70 11 CoV CoV NNP cord-286950-j7m69833 70 12 in in IN cord-286950-j7m69833 70 13 wild wild JJ cord-286950-j7m69833 70 14 - - HYPH cord-286950-j7m69833 70 15 type type NN cord-286950-j7m69833 70 16 mice mouse NNS cord-286950-j7m69833 70 17 have have VBP cord-286950-j7m69833 70 18 been be VBN cord-286950-j7m69833 70 19 prohibited prohibit VBN cord-286950-j7m69833 70 20 [ [ -LRB- cord-286950-j7m69833 70 21 26 26 CD cord-286950-j7m69833 70 22 ; ; : cord-286950-j7m69833 70 23 R. R. NNP cord-286950-j7m69833 70 24 Baric Baric NNP cord-286950-j7m69833 70 25 , , , cord-286950-j7m69833 70 26 personal personal JJ cord-286950-j7m69833 70 27 communication communication NN cord-286950-j7m69833 70 28 ] ] -RRB- cord-286950-j7m69833 70 29 . . . cord-286950-j7m69833 71 1 The the DT cord-286950-j7m69833 71 2 question question NN cord-286950-j7m69833 71 3 remains remain VBZ cord-286950-j7m69833 71 4 , , , cord-286950-j7m69833 71 5 how how WRB cord-286950-j7m69833 71 6 does do VBZ cord-286950-j7m69833 71 7 society society NN cord-286950-j7m69833 71 8 at at IN cord-286950-j7m69833 71 9 large large JJ cord-286950-j7m69833 71 10 , , , cord-286950-j7m69833 71 11 and and CC cord-286950-j7m69833 71 12 the the DT cord-286950-j7m69833 71 13 scientific scientific JJ cord-286950-j7m69833 71 14 community community NN cord-286950-j7m69833 71 15 and and CC cord-286950-j7m69833 71 16 regulatory regulatory JJ cord-286950-j7m69833 71 17 agencies agency NNS cord-286950-j7m69833 71 18 in in IN cord-286950-j7m69833 71 19 particular particular JJ cord-286950-j7m69833 71 20 , , , cord-286950-j7m69833 71 21 weigh weigh VB cord-286950-j7m69833 71 22 the the DT cord-286950-j7m69833 71 23 risks risk NNS cord-286950-j7m69833 71 24 and and CC cord-286950-j7m69833 71 25 benefits benefit NNS cord-286950-j7m69833 71 26 ? ? . cord-286950-j7m69833 72 1 The the DT cord-286950-j7m69833 72 2 difficulty difficulty NN cord-286950-j7m69833 72 3 lies lie VBZ cord-286950-j7m69833 72 4 largely largely RB cord-286950-j7m69833 72 5 in in IN cord-286950-j7m69833 72 6 trying try VBG cord-286950-j7m69833 72 7 to to TO cord-286950-j7m69833 72 8 apply apply VB cord-286950-j7m69833 72 9 quantitative quantitative JJ cord-286950-j7m69833 72 10 risk risk NN cord-286950-j7m69833 72 11 assessment assessment NN cord-286950-j7m69833 72 12 measures measure NNS cord-286950-j7m69833 72 13 to to IN cord-286950-j7m69833 72 14 the the DT cord-286950-j7m69833 72 15 problem problem NN cord-286950-j7m69833 72 16 . . . cord-286950-j7m69833 73 1 The the DT cord-286950-j7m69833 73 2 benefits benefit NNS cord-286950-j7m69833 73 3 of of IN cord-286950-j7m69833 73 4 all all DT cord-286950-j7m69833 73 5 biological biological JJ cord-286950-j7m69833 73 6 research research NN cord-286950-j7m69833 73 7 , , , cord-286950-j7m69833 73 8 not not RB cord-286950-j7m69833 73 9 just just RB cord-286950-j7m69833 73 10 GOF GOF NNP cord-286950-j7m69833 73 11 research research NN cord-286950-j7m69833 73 12 , , , cord-286950-j7m69833 73 13 often often RB cord-286950-j7m69833 73 14 do do VBP cord-286950-j7m69833 73 15 not not RB cord-286950-j7m69833 73 16 make make VB cord-286950-j7m69833 73 17 themselves -PRON- PRP cord-286950-j7m69833 73 18 apparent apparent JJ cord-286950-j7m69833 73 19 until until IN cord-286950-j7m69833 73 20 years year NNS cord-286950-j7m69833 73 21 or or CC cord-286950-j7m69833 73 22 even even RB cord-286950-j7m69833 73 23 decades decade NNS cord-286950-j7m69833 73 24 after after IN cord-286950-j7m69833 73 25 the the DT cord-286950-j7m69833 73 26 experiments experiment NNS cord-286950-j7m69833 73 27 are be VBP cord-286950-j7m69833 73 28 performed perform VBN cord-286950-j7m69833 73 29 . . . cord-286950-j7m69833 74 1 On on IN cord-286950-j7m69833 74 2 the the DT cord-286950-j7m69833 74 3 other other JJ cord-286950-j7m69833 74 4 hand hand NN cord-286950-j7m69833 74 5 , , , cord-286950-j7m69833 74 6 the the DT cord-286950-j7m69833 74 7 risks risk NNS cord-286950-j7m69833 74 8 , , , cord-286950-j7m69833 74 9 even even RB cord-286950-j7m69833 74 10 when when WRB cord-286950-j7m69833 74 11 theoretical theoretical JJ cord-286950-j7m69833 74 12 , , , cord-286950-j7m69833 74 13 manifest manifest VBP cord-286950-j7m69833 74 14 themselves -PRON- PRP cord-286950-j7m69833 74 15 in in IN cord-286950-j7m69833 74 16 the the DT cord-286950-j7m69833 74 17 present present NN cord-286950-j7m69833 74 18 when when WRB cord-286950-j7m69833 74 19 the the DT cord-286950-j7m69833 74 20 experimentation experimentation NN cord-286950-j7m69833 74 21 is be VBZ cord-286950-j7m69833 74 22 done do VBN cord-286950-j7m69833 74 23 . . . cord-286950-j7m69833 75 1 Fortunately fortunately RB cord-286950-j7m69833 75 2 , , , cord-286950-j7m69833 75 3 we -PRON- PRP cord-286950-j7m69833 75 4 have have VBP cord-286950-j7m69833 75 5 not not RB cord-286950-j7m69833 75 6 had have VBN cord-286950-j7m69833 75 7 real real JJ cord-286950-j7m69833 75 8 examples example NNS cord-286950-j7m69833 75 9 of of IN cord-286950-j7m69833 75 10 laboratory laboratory NN cord-286950-j7m69833 75 11 accidents accident NNS cord-286950-j7m69833 75 12 leading lead VBG cord-286950-j7m69833 75 13 to to IN cord-286950-j7m69833 75 14 significant significant JJ cord-286950-j7m69833 75 15 morbidity morbidity NN cord-286950-j7m69833 75 16 or or CC cord-286950-j7m69833 75 17 mortality mortality NN cord-286950-j7m69833 75 18 . . . cord-286950-j7m69833 76 1 The the DT cord-286950-j7m69833 76 2 1977 1977 CD cord-286950-j7m69833 76 3 reintroduction reintroduction NN cord-286950-j7m69833 76 4 of of IN cord-286950-j7m69833 76 5 H1N1 H1N1 NNP cord-286950-j7m69833 76 6 into into IN cord-286950-j7m69833 76 7 human human JJ cord-286950-j7m69833 76 8 circulation circulation NN cord-286950-j7m69833 76 9 has have VBZ cord-286950-j7m69833 76 10 been be VBN cord-286950-j7m69833 76 11 attributed attribute VBN cord-286950-j7m69833 76 12 to to IN cord-286950-j7m69833 76 13 a a DT cord-286950-j7m69833 76 14 laboratory laboratory NN cord-286950-j7m69833 76 15 mishap mishap NN cord-286950-j7m69833 76 16 , , , cord-286950-j7m69833 76 17 although although IN cord-286950-j7m69833 76 18 not not RB cord-286950-j7m69833 76 19 all all DT cord-286950-j7m69833 76 20 agree agree VBP cord-286950-j7m69833 76 21 since since IN cord-286950-j7m69833 76 22 other other JJ cord-286950-j7m69833 76 23 explanations explanation NNS cord-286950-j7m69833 76 24 are be VBP cord-286950-j7m69833 76 25 possible possible JJ cord-286950-j7m69833 76 26 [ [ -LRB- cord-286950-j7m69833 76 27 27 27 CD cord-286950-j7m69833 76 28 ] ] -RRB- cord-286950-j7m69833 77 1 [ [ -LRB- cord-286950-j7m69833 77 2 28 28 CD cord-286950-j7m69833 77 3 ] ] -RRB- cord-286950-j7m69833 77 4 [ [ -LRB- cord-286950-j7m69833 77 5 29 29 CD cord-286950-j7m69833 77 6 ] ] -RRB- cord-286950-j7m69833 77 7 . . . cord-286950-j7m69833 78 1 As as IN cord-286950-j7m69833 78 2 discussed discuss VBN cord-286950-j7m69833 78 3 below below RB cord-286950-j7m69833 78 4 , , , cord-286950-j7m69833 78 5 some some DT cord-286950-j7m69833 78 6 authorities authority NNS cord-286950-j7m69833 78 7 have have VBP cord-286950-j7m69833 78 8 presented present VBN cord-286950-j7m69833 78 9 worst bad JJS cord-286950-j7m69833 78 10 - - HYPH cord-286950-j7m69833 78 11 case case NN cord-286950-j7m69833 78 12 scenarios scenario NNS cord-286950-j7m69833 78 13 based base VBN cord-286950-j7m69833 78 14 on on IN cord-286950-j7m69833 78 15 hypothetical hypothetical JJ cord-286950-j7m69833 78 16 calculations calculation NNS cord-286950-j7m69833 78 17 , , , cord-286950-j7m69833 78 18 whereas whereas IN cord-286950-j7m69833 78 19 others other NNS cord-286950-j7m69833 78 20 have have VBP cord-286950-j7m69833 78 21 used use VBN cord-286950-j7m69833 78 22 similar similar JJ cord-286950-j7m69833 78 23 types type NNS cord-286950-j7m69833 78 24 of of IN cord-286950-j7m69833 78 25 data datum NNS cord-286950-j7m69833 78 26 to to TO cord-286950-j7m69833 78 27 come come VB cord-286950-j7m69833 78 28 up up RP cord-286950-j7m69833 78 29 with with IN cord-286950-j7m69833 78 30 numbers number NNS cord-286950-j7m69833 78 31 at at IN cord-286950-j7m69833 78 32 the the DT cord-286950-j7m69833 78 33 extreme extreme JJ cord-286950-j7m69833 78 34 opposite opposite JJ cord-286950-j7m69833 78 35 end end NN cord-286950-j7m69833 78 36 of of IN cord-286950-j7m69833 78 37 the the DT cord-286950-j7m69833 78 38 spectrum spectrum NN cord-286950-j7m69833 78 39 , , , cord-286950-j7m69833 78 40 arguing argue VBG cord-286950-j7m69833 78 41 that that IN cord-286950-j7m69833 78 42 the the DT cord-286950-j7m69833 78 43 likelihood likelihood NN cord-286950-j7m69833 78 44 of of IN cord-286950-j7m69833 78 45 such such JJ cord-286950-j7m69833 78 46 events event NNS cord-286950-j7m69833 78 47 is be VBZ cord-286950-j7m69833 78 48 extremely extremely RB cord-286950-j7m69833 78 49 low low JJ cord-286950-j7m69833 78 50 . . . cord-286950-j7m69833 79 1 Perhaps perhaps RB cord-286950-j7m69833 79 2 the the DT cord-286950-j7m69833 79 3 greatest great JJS cord-286950-j7m69833 79 4 benefit benefit NN cord-286950-j7m69833 79 5 of of IN cord-286950-j7m69833 79 6 this this DT cord-286950-j7m69833 79 7 controversy controversy NN cord-286950-j7m69833 79 8 has have VBZ cord-286950-j7m69833 79 9 been be VBN cord-286950-j7m69833 79 10 an an DT cord-286950-j7m69833 79 11 increased increase VBN cord-286950-j7m69833 79 12 attention attention NN cord-286950-j7m69833 79 13 to to IN cord-286950-j7m69833 79 14 biosafety biosafety NN cord-286950-j7m69833 79 15 when when WRB cord-286950-j7m69833 79 16 working work VBG cord-286950-j7m69833 79 17 with with IN cord-286950-j7m69833 79 18 dangerous dangerous JJ cord-286950-j7m69833 79 19 pathogens pathogen NNS cord-286950-j7m69833 79 20 . . . cord-286950-j7m69833 80 1 In in IN cord-286950-j7m69833 80 2 2014 2014 CD cord-286950-j7m69833 80 3 , , , cord-286950-j7m69833 80 4 the the DT cord-286950-j7m69833 80 5 NIH NIH NNP cord-286950-j7m69833 80 6 proposed propose VBD cord-286950-j7m69833 80 7 a a DT cord-286950-j7m69833 80 8 Biosafety Biosafety NNP cord-286950-j7m69833 80 9 Stewardship Stewardship NNP cord-286950-j7m69833 80 10 Month Month NNP cord-286950-j7m69833 80 11 as as IN cord-286950-j7m69833 80 12 a a DT cord-286950-j7m69833 80 13 means means NN cord-286950-j7m69833 80 14 to to TO cord-286950-j7m69833 80 15 promote promote VB cord-286950-j7m69833 80 16 increased increase VBN cord-286950-j7m69833 80 17 attention attention NN cord-286950-j7m69833 80 18 to to IN cord-286950-j7m69833 80 19 biosafety biosafety NN cord-286950-j7m69833 80 20 , , , cord-286950-j7m69833 80 21 and and CC cord-286950-j7m69833 80 22 many many JJ cord-286950-j7m69833 80 23 institutions institution NNS cord-286950-j7m69833 80 24 took take VBD cord-286950-j7m69833 80 25 advantage advantage NN cord-286950-j7m69833 80 26 of of IN cord-286950-j7m69833 80 27 this this DT cord-286950-j7m69833 80 28 opportunity opportunity NN cord-286950-j7m69833 80 29 . . . cord-286950-j7m69833 81 1 Indeed indeed RB cord-286950-j7m69833 81 2 , , , cord-286950-j7m69833 81 3 while while IN cord-286950-j7m69833 81 4 it -PRON- PRP cord-286950-j7m69833 81 5 can can MD cord-286950-j7m69833 81 6 be be VB cord-286950-j7m69833 81 7 misleading mislead VBG cord-286950-j7m69833 81 8 to to TO cord-286950-j7m69833 81 9 draw draw VB cord-286950-j7m69833 81 10 strong strong JJ cord-286950-j7m69833 81 11 conclusions conclusion NNS cord-286950-j7m69833 81 12 from from IN cord-286950-j7m69833 81 13 the the DT cord-286950-j7m69833 81 14 absence absence NN cord-286950-j7m69833 81 15 of of IN cord-286950-j7m69833 81 16 events event NNS cord-286950-j7m69833 81 17 , , , cord-286950-j7m69833 81 18 the the DT cord-286950-j7m69833 81 19 types type NNS cord-286950-j7m69833 81 20 of of IN cord-286950-j7m69833 81 21 events event NNS cord-286950-j7m69833 81 22 that that WDT cord-286950-j7m69833 81 23 found find VBD cord-286950-j7m69833 81 24 their -PRON- PRP$ cord-286950-j7m69833 81 25 way way NN cord-286950-j7m69833 81 26 into into IN cord-286950-j7m69833 81 27 the the DT cord-286950-j7m69833 81 28 news news NN cord-286950-j7m69833 81 29 media medium NNS cord-286950-j7m69833 81 30 earlier early RBR cord-286950-j7m69833 81 31 in in IN cord-286950-j7m69833 81 32 this this DT cord-286950-j7m69833 81 33 decade decade NN cord-286950-j7m69833 81 34 seem seem VB cord-286950-j7m69833 81 35 to to TO cord-286950-j7m69833 81 36 have have VB cord-286950-j7m69833 81 37 decreased decrease VBN cord-286950-j7m69833 81 38 significantly significantly RB cord-286950-j7m69833 81 39 . . . cord-286950-j7m69833 82 1 Another another DT cord-286950-j7m69833 82 2 benefit benefit NN cord-286950-j7m69833 82 3 of of IN cord-286950-j7m69833 82 4 the the DT cord-286950-j7m69833 82 5 controversy controversy NN cord-286950-j7m69833 82 6 was be VBD cord-286950-j7m69833 82 7 that that IN cord-286950-j7m69833 82 8 it -PRON- PRP cord-286950-j7m69833 82 9 has have VBZ cord-286950-j7m69833 82 10 stimulated stimulate VBN cord-286950-j7m69833 82 11 efforts effort NNS cord-286950-j7m69833 82 12 to to TO cord-286950-j7m69833 82 13 gain gain VB cord-286950-j7m69833 82 14 comparable comparable JJ cord-286950-j7m69833 82 15 information information NN cord-286950-j7m69833 82 16 in in IN cord-286950-j7m69833 82 17 systems system NNS cord-286950-j7m69833 82 18 that that WDT cord-286950-j7m69833 82 19 do do VBP cord-286950-j7m69833 82 20 pose pose VB cord-286950-j7m69833 82 21 the the DT cord-286950-j7m69833 82 22 same same JJ cord-286950-j7m69833 82 23 biosafety biosafety NN cord-286950-j7m69833 82 24 or or CC cord-286950-j7m69833 82 25 biosecurity biosecurity NN cord-286950-j7m69833 82 26 risks risk NNS cord-286950-j7m69833 82 27 as as IN cord-286950-j7m69833 82 28 working work VBG cord-286950-j7m69833 82 29 on on IN cord-286950-j7m69833 82 30 the the DT cord-286950-j7m69833 82 31 wild wild JJ cord-286950-j7m69833 82 32 - - HYPH cord-286950-j7m69833 82 33 type type NN cord-286950-j7m69833 82 34 virus virus NN cord-286950-j7m69833 82 35 . . . cord-286950-j7m69833 83 1 For for IN cord-286950-j7m69833 83 2 example example NN cord-286950-j7m69833 83 3 , , , cord-286950-j7m69833 83 4 a a DT cord-286950-j7m69833 83 5 recent recent JJ cord-286950-j7m69833 83 6 study study NN cord-286950-j7m69833 83 7 reporting report VBG cord-286950-j7m69833 83 8 that that IN cord-286950-j7m69833 83 9 only only RB cord-286950-j7m69833 83 10 three three CD cord-286950-j7m69833 83 11 mutations mutation NNS cord-286950-j7m69833 83 12 were be VBD cord-286950-j7m69833 83 13 needed need VBN cord-286950-j7m69833 83 14 to to TO cord-286950-j7m69833 83 15 switch switch VB cord-286950-j7m69833 83 16 H7N9 H7N9 NNP cord-286950-j7m69833 83 17 tropism tropism NN cord-286950-j7m69833 83 18 to to IN cord-286950-j7m69833 83 19 human human JJ cord-286950-j7m69833 83 20 cells cell NNS cord-286950-j7m69833 83 21 was be VBD cord-286950-j7m69833 83 22 performed perform VBN cord-286950-j7m69833 83 23 using use VBG cord-286950-j7m69833 83 24 an an DT cord-286950-j7m69833 83 25 attenuated attenuated JJ cord-286950-j7m69833 83 26 virus virus NN cord-286950-j7m69833 83 27 [ [ -LRB- cord-286950-j7m69833 83 28 30 30 CD cord-286950-j7m69833 83 29 ] ] -RRB- cord-286950-j7m69833 83 30 . . . cord-286950-j7m69833 84 1 GOF GOF NNP cord-286950-j7m69833 84 2 research research NN cord-286950-j7m69833 84 3 , , , cord-286950-j7m69833 84 4 especially especially RB cord-286950-j7m69833 84 5 that that IN cord-286950-j7m69833 84 6 involving involve VBG cord-286950-j7m69833 84 7 a a DT cord-286950-j7m69833 84 8 PPP PPP NNP cord-286950-j7m69833 84 9 , , , cord-286950-j7m69833 84 10 has have VBZ cord-286950-j7m69833 84 11 become become VBN cord-286950-j7m69833 84 12 the the DT cord-286950-j7m69833 84 13 focus focus NN cord-286950-j7m69833 84 14 of of IN cord-286950-j7m69833 84 15 intense intense JJ cord-286950-j7m69833 84 16 ethical ethical JJ cord-286950-j7m69833 84 17 debate debate NN cord-286950-j7m69833 84 18 in in IN cord-286950-j7m69833 84 19 the the DT cord-286950-j7m69833 84 20 wake wake NN cord-286950-j7m69833 84 21 of of IN cord-286950-j7m69833 84 22 the the DT cord-286950-j7m69833 84 23 2014 2014 CD cord-286950-j7m69833 84 24 moratorium moratorium NN cord-286950-j7m69833 84 25 . . . cord-286950-j7m69833 85 1 The the DT cord-286950-j7m69833 85 2 ethical ethical JJ cord-286950-j7m69833 85 3 concerns concern NNS cord-286950-j7m69833 85 4 have have VBP cord-286950-j7m69833 85 5 been be VBN cord-286950-j7m69833 85 6 formulated formulate VBN cord-286950-j7m69833 85 7 along along IN cord-286950-j7m69833 85 8 three three CD cord-286950-j7m69833 85 9 main main JJ cord-286950-j7m69833 85 10 axes axis NNS cord-286950-j7m69833 85 11 of of IN cord-286950-j7m69833 85 12 criticism criticism NN cord-286950-j7m69833 85 13 . . . cord-286950-j7m69833 86 1 The the DT cord-286950-j7m69833 86 2 first first JJ cord-286950-j7m69833 86 3 concern concern NN cord-286950-j7m69833 86 4 is be VBZ cord-286950-j7m69833 86 5 the the DT cord-286950-j7m69833 86 6 potential potential NN cord-286950-j7m69833 86 7 for for IN cord-286950-j7m69833 86 8 misuse misuse NN cord-286950-j7m69833 86 9 of of IN cord-286950-j7m69833 86 10 any any DT cord-286950-j7m69833 86 11 information information NN cord-286950-j7m69833 86 12 or or CC cord-286950-j7m69833 86 13 product product NN cord-286950-j7m69833 86 14 generated generate VBN cord-286950-j7m69833 86 15 by by IN cord-286950-j7m69833 86 16 GOF GOF NNP cord-286950-j7m69833 86 17 research research NN cord-286950-j7m69833 86 18 by by IN cord-286950-j7m69833 86 19 bad bad JJ cord-286950-j7m69833 86 20 actors actor NNS cord-286950-j7m69833 86 21 . . . cord-286950-j7m69833 87 1 The the DT cord-286950-j7m69833 87 2 worry worry NN cord-286950-j7m69833 87 3 here here RB cord-286950-j7m69833 87 4 is be VBZ cord-286950-j7m69833 87 5 that that IN cord-286950-j7m69833 87 6 , , , cord-286950-j7m69833 87 7 once once IN cord-286950-j7m69833 87 8 the the DT cord-286950-j7m69833 87 9 results result NNS cord-286950-j7m69833 87 10 of of IN cord-286950-j7m69833 87 11 GOF GOF NNP cord-286950-j7m69833 87 12 studies study NNS cord-286950-j7m69833 87 13 are be VBP cord-286950-j7m69833 87 14 published publish VBN cord-286950-j7m69833 87 15 , , , cord-286950-j7m69833 87 16 bad bad JJ cord-286950-j7m69833 87 17 actors actor NNS cord-286950-j7m69833 87 18 could could MD cord-286950-j7m69833 87 19 replicate replicate VB cord-286950-j7m69833 87 20 the the DT cord-286950-j7m69833 87 21 work work NN cord-286950-j7m69833 87 22 for for IN cord-286950-j7m69833 87 23 nefarious nefarious JJ cord-286950-j7m69833 87 24 purposes purpose NNS cord-286950-j7m69833 87 25 , , , cord-286950-j7m69833 87 26 such such JJ cord-286950-j7m69833 87 27 as as IN cord-286950-j7m69833 87 28 a a DT cord-286950-j7m69833 87 29 terrorist terrorist JJ cord-286950-j7m69833 87 30 attack attack NN cord-286950-j7m69833 87 31 . . . cord-286950-j7m69833 88 1 Such such JJ cord-286950-j7m69833 88 2 concerns concern NNS cord-286950-j7m69833 88 3 were be VBD cord-286950-j7m69833 88 4 expressed express VBN cord-286950-j7m69833 88 5 , , , cord-286950-j7m69833 88 6 for for IN cord-286950-j7m69833 88 7 example example NN cord-286950-j7m69833 88 8 , , , cord-286950-j7m69833 88 9 in in IN cord-286950-j7m69833 88 10 connection connection NN cord-286950-j7m69833 88 11 with with IN cord-286950-j7m69833 88 12 the the DT cord-286950-j7m69833 88 13 aforementioned aforementioned JJ cord-286950-j7m69833 88 14 2012 2012 CD cord-286950-j7m69833 88 15 publication publication NN cord-286950-j7m69833 88 16 of of IN cord-286950-j7m69833 88 17 studies study NNS cord-286950-j7m69833 88 18 of of IN cord-286950-j7m69833 88 19 engineered engineer VBN cord-286950-j7m69833 88 20 avian avian JJ cord-286950-j7m69833 88 21 flu flu NN cord-286950-j7m69833 88 22 virus virus NN cord-286950-j7m69833 88 23 transmissibility transmissibility NN cord-286950-j7m69833 88 24 in in IN cord-286950-j7m69833 88 25 ferret ferret JJ cord-286950-j7m69833 88 26 models model NNS cord-286950-j7m69833 88 27 [ [ -LRB- cord-286950-j7m69833 88 28 5 5 CD cord-286950-j7m69833 88 29 , , , cord-286950-j7m69833 88 30 3 3 CD cord-286950-j7m69833 88 31 , , , cord-286950-j7m69833 88 32 4 4 CD cord-286950-j7m69833 88 33 ] ] -RRB- cord-286950-j7m69833 88 34 . . . cord-286950-j7m69833 89 1 As as IN cord-286950-j7m69833 89 2 noted note VBN cord-286950-j7m69833 89 3 above above RB cord-286950-j7m69833 89 4 , , , cord-286950-j7m69833 89 5 the the DT cord-286950-j7m69833 89 6 question question NN cord-286950-j7m69833 89 7 whether whether IN cord-286950-j7m69833 89 8 to to TO cord-286950-j7m69833 89 9 permit permit VB cord-286950-j7m69833 89 10 publication publication NN cord-286950-j7m69833 89 11 was be VBD cord-286950-j7m69833 89 12 considered consider VBN cord-286950-j7m69833 89 13 by by IN cord-286950-j7m69833 89 14 the the DT cord-286950-j7m69833 89 15 NSABB NSABB NNP cord-286950-j7m69833 89 16 , , , cord-286950-j7m69833 89 17 which which WDT cord-286950-j7m69833 89 18 eventually eventually RB cord-286950-j7m69833 89 19 allowed allow VBD cord-286950-j7m69833 89 20 publication publication NN cord-286950-j7m69833 89 21 , , , cord-286950-j7m69833 89 22 judging judge VBG cord-286950-j7m69833 89 23 that that IN cord-286950-j7m69833 89 24 the the DT cord-286950-j7m69833 89 25 risk risk NN cord-286950-j7m69833 89 26 of of IN cord-286950-j7m69833 89 27 misuse misuse NN cord-286950-j7m69833 89 28 was be VBD cord-286950-j7m69833 89 29 outweighed outweigh VBN cord-286950-j7m69833 89 30 by by IN cord-286950-j7m69833 89 31 the the DT cord-286950-j7m69833 89 32 potential potential JJ cord-286950-j7m69833 89 33 benefits benefit NNS cord-286950-j7m69833 89 34 . . . cord-286950-j7m69833 90 1 This this DT cord-286950-j7m69833 90 2 is be VBZ cord-286950-j7m69833 90 3 neither neither CC cord-286950-j7m69833 90 4 the the DT cord-286950-j7m69833 90 5 first first JJ cord-286950-j7m69833 90 6 nor nor CC cord-286950-j7m69833 90 7 the the DT cord-286950-j7m69833 90 8 last last JJ cord-286950-j7m69833 90 9 occasion occasion NN cord-286950-j7m69833 90 10 on on IN cord-286950-j7m69833 90 11 which which WDT cord-286950-j7m69833 90 12 questions question NNS cord-286950-j7m69833 90 13 have have VBP cord-286950-j7m69833 90 14 been be VBN cord-286950-j7m69833 90 15 raised raise VBN cord-286950-j7m69833 90 16 about about IN cord-286950-j7m69833 90 17 the the DT cord-286950-j7m69833 90 18 risks risk NNS cord-286950-j7m69833 90 19 of of IN cord-286950-j7m69833 90 20 dual dual JJ cord-286950-j7m69833 90 21 - - HYPH cord-286950-j7m69833 90 22 use use NN cord-286950-j7m69833 90 23 research research NN cord-286950-j7m69833 90 24 , , , cord-286950-j7m69833 90 25 with with IN cord-286950-j7m69833 90 26 examples example NNS cord-286950-j7m69833 90 27 ranging range VBG cord-286950-j7m69833 90 28 far far RB cord-286950-j7m69833 90 29 beyond beyond IN cord-286950-j7m69833 90 30 biomedical biomedical JJ cord-286950-j7m69833 90 31 research research NN cord-286950-j7m69833 90 32 to to TO cord-286950-j7m69833 90 33 include include VB cord-286950-j7m69833 90 34 such such JJ cord-286950-j7m69833 90 35 technologies technology NNS cord-286950-j7m69833 90 36 as as IN cord-286950-j7m69833 90 37 unmanned unmanned JJ cord-286950-j7m69833 90 38 aerial aerial JJ cord-286950-j7m69833 90 39 vehicles vehicle NNS cord-286950-j7m69833 90 40 being be VBG cord-286950-j7m69833 90 41 used use VBN cord-286950-j7m69833 90 42 as as IN cord-286950-j7m69833 90 43 weapons weapon NNS cord-286950-j7m69833 90 44 and and CC cord-286950-j7m69833 90 45 hacking hacking NN cord-286950-j7m69833 90 46 being be VBG cord-286950-j7m69833 90 47 used use VBN cord-286950-j7m69833 90 48 for for IN cord-286950-j7m69833 90 49 the the DT cord-286950-j7m69833 90 50 Stuxnet Stuxnet NNP cord-286950-j7m69833 90 51 cyberattack cyberattack NN cord-286950-j7m69833 90 52 . . . cord-286950-j7m69833 91 1 Cyberwarfare cyberwarfare NN cord-286950-j7m69833 91 2 tools tool NNS cord-286950-j7m69833 91 3 can can MD cord-286950-j7m69833 91 4 be be VB cord-286950-j7m69833 91 5 used use VBN cord-286950-j7m69833 91 6 to to TO cord-286950-j7m69833 91 7 enhance enhance VB cord-286950-j7m69833 91 8 national national JJ cord-286950-j7m69833 91 9 security security NN cord-286950-j7m69833 91 10 by by IN cord-286950-j7m69833 91 11 disarming disarm VBG cord-286950-j7m69833 91 12 opponents opponent NNS cord-286950-j7m69833 91 13 while while IN cord-286950-j7m69833 91 14 at at IN cord-286950-j7m69833 91 15 the the DT cord-286950-j7m69833 91 16 same same JJ cord-286950-j7m69833 91 17 time time NN cord-286950-j7m69833 91 18 finding find VBG cord-286950-j7m69833 91 19 employment employment NN cord-286950-j7m69833 91 20 in in IN cord-286950-j7m69833 91 21 crime crime NN cord-286950-j7m69833 91 22 such such JJ cord-286950-j7m69833 91 23 as as IN cord-286950-j7m69833 91 24 occurred occur VBN cord-286950-j7m69833 91 25 recently recently RB cord-286950-j7m69833 91 26 when when WRB cord-286950-j7m69833 91 27 the the DT cord-286950-j7m69833 91 28 leaked leak VBN cord-286950-j7m69833 91 29 National National NNP cord-286950-j7m69833 91 30 Security Security NNP cord-286950-j7m69833 91 31 Agency Agency NNP cord-286950-j7m69833 91 32 code code NN cord-286950-j7m69833 91 33 was be VBD cord-286950-j7m69833 91 34 used use VBN cord-286950-j7m69833 91 35 in in IN cord-286950-j7m69833 91 36 Spring Spring NNP cord-286950-j7m69833 91 37 2017 2017 CD cord-286950-j7m69833 91 38 for for IN cord-286950-j7m69833 91 39 global global JJ cord-286950-j7m69833 91 40 ransomware ransomware NN cord-286950-j7m69833 91 41 attacks attack NNS cord-286950-j7m69833 91 42 . . . cord-286950-j7m69833 92 1 Such such JJ cord-286950-j7m69833 92 2 misuse misuse NN cord-286950-j7m69833 92 3 of of IN cord-286950-j7m69833 92 4 GOF GOF NNP cord-286950-j7m69833 92 5 research research NN cord-286950-j7m69833 92 6 is be VBZ cord-286950-j7m69833 92 7 certainly certainly RB cord-286950-j7m69833 92 8 possible possible JJ cord-286950-j7m69833 92 9 . . . cord-286950-j7m69833 93 1 But but CC cord-286950-j7m69833 93 2 one one CD cord-286950-j7m69833 93 3 serious serious JJ cord-286950-j7m69833 93 4 problem problem NN cord-286950-j7m69833 93 5 in in IN cord-286950-j7m69833 93 6 an an DT cord-286950-j7m69833 93 7 ethical ethical JJ cord-286950-j7m69833 93 8 evaluation evaluation NN cord-286950-j7m69833 93 9 of of IN cord-286950-j7m69833 93 10 possible possible JJ cord-286950-j7m69833 93 11 misuse misuse NN cord-286950-j7m69833 93 12 is be VBZ cord-286950-j7m69833 93 13 the the DT cord-286950-j7m69833 93 14 difficulty difficulty NN cord-286950-j7m69833 93 15 of of IN cord-286950-j7m69833 93 16 estimating estimate VBG cord-286950-j7m69833 93 17 the the DT cord-286950-j7m69833 93 18 likelihood likelihood NN cord-286950-j7m69833 93 19 and and CC cord-286950-j7m69833 93 20 potential potential JJ cord-286950-j7m69833 93 21 impact impact NN cord-286950-j7m69833 93 22 of of IN cord-286950-j7m69833 93 23 misuse misuse NN cord-286950-j7m69833 93 24 . . . cord-286950-j7m69833 94 1 One one PRP cord-286950-j7m69833 94 2 can can MD cord-286950-j7m69833 94 3 imagine imagine VB cord-286950-j7m69833 94 4 numerous numerous JJ cord-286950-j7m69833 94 5 different different JJ cord-286950-j7m69833 94 6 scenarios scenario NNS cord-286950-j7m69833 94 7 involving involve VBG cord-286950-j7m69833 94 8 everyone everyone NN cord-286950-j7m69833 94 9 from from IN cord-286950-j7m69833 94 10 major major JJ cord-286950-j7m69833 94 11 state state NN cord-286950-j7m69833 94 12 actors actor NNS cord-286950-j7m69833 94 13 and and CC cord-286950-j7m69833 94 14 non non JJ cord-286950-j7m69833 94 15 - - JJ cord-286950-j7m69833 94 16 state state JJ cord-286950-j7m69833 94 17 terrorist terrorist JJ cord-286950-j7m69833 94 18 organizations organization NNS cord-286950-j7m69833 94 19 to to IN cord-286950-j7m69833 94 20 freelance freelance JJ cord-286950-j7m69833 94 21 mischief mischief NN cord-286950-j7m69833 94 22 - - HYPH cord-286950-j7m69833 94 23 makers maker NNS cord-286950-j7m69833 94 24 working work VBG cord-286950-j7m69833 94 25 in in IN cord-286950-j7m69833 94 26 a a DT cord-286950-j7m69833 94 27 home home NN cord-286950-j7m69833 94 28 basement basement NN cord-286950-j7m69833 94 29 lab lab NN cord-286950-j7m69833 94 30 . . . cord-286950-j7m69833 95 1 There there EX cord-286950-j7m69833 95 2 is be VBZ cord-286950-j7m69833 95 3 no no DT cord-286950-j7m69833 95 4 way way NN cord-286950-j7m69833 95 5 to to TO cord-286950-j7m69833 95 6 quantify quantify VB cord-286950-j7m69833 95 7 over over IN cord-286950-j7m69833 95 8 so so RB cord-286950-j7m69833 95 9 many many JJ cord-286950-j7m69833 95 10 possibilities possibility NNS cord-286950-j7m69833 95 11 , , , cord-286950-j7m69833 95 12 let let VB cord-286950-j7m69833 95 13 alone alone RB cord-286950-j7m69833 95 14 to to TO cord-286950-j7m69833 95 15 assay assay VB cord-286950-j7m69833 95 16 systematically systematically RB cord-286950-j7m69833 95 17 the the DT cord-286950-j7m69833 95 18 effects effect NNS cord-286950-j7m69833 95 19 that that WDT cord-286950-j7m69833 95 20 such such PDT cord-286950-j7m69833 95 21 a a DT cord-286950-j7m69833 95 22 diverse diverse JJ cord-286950-j7m69833 95 23 array array NN cord-286950-j7m69833 95 24 of of IN cord-286950-j7m69833 95 25 actors actor NNS cord-286950-j7m69833 95 26 might may MD cord-286950-j7m69833 95 27 achieve achieve VB cord-286950-j7m69833 95 28 . . . cord-286950-j7m69833 96 1 The the DT cord-286950-j7m69833 96 2 misuse misuse JJ cord-286950-j7m69833 96 3 concern concern NN cord-286950-j7m69833 96 4 is be VBZ cord-286950-j7m69833 96 5 further far RBR cord-286950-j7m69833 96 6 complicated complicate VBN cord-286950-j7m69833 96 7 by by IN cord-286950-j7m69833 96 8 the the DT cord-286950-j7m69833 96 9 fact fact NN cord-286950-j7m69833 96 10 that that IN cord-286950-j7m69833 96 11 the the DT cord-286950-j7m69833 96 12 cost cost NN cord-286950-j7m69833 96 13 and and CC cord-286950-j7m69833 96 14 complexity complexity NN cord-286950-j7m69833 96 15 of of IN cord-286950-j7m69833 96 16 using use VBG cord-286950-j7m69833 96 17 relevant relevant JJ cord-286950-j7m69833 96 18 tools tool NNS cord-286950-j7m69833 96 19 , , , cord-286950-j7m69833 96 20 such such JJ cord-286950-j7m69833 96 21 as as IN cord-286950-j7m69833 96 22 CRISPR CRISPR NNP cord-286950-j7m69833 96 23 / / SYM cord-286950-j7m69833 96 24 Cas9 Cas9 NNP cord-286950-j7m69833 96 25 , , , cord-286950-j7m69833 96 26 continues continue VBZ cord-286950-j7m69833 96 27 to to TO cord-286950-j7m69833 96 28 decline decline VB cord-286950-j7m69833 96 29 , , , cord-286950-j7m69833 96 30 making make VBG cord-286950-j7m69833 96 31 ever ever RB cord-286950-j7m69833 96 32 easier easy JJR cord-286950-j7m69833 96 33 the the DT cord-286950-j7m69833 96 34 replication replication NN cord-286950-j7m69833 96 35 of of IN cord-286950-j7m69833 96 36 even even RB cord-286950-j7m69833 96 37 unpublished unpublished JJ cord-286950-j7m69833 96 38 research research NN cord-286950-j7m69833 96 39 . . . cord-286950-j7m69833 97 1 Indeed indeed RB cord-286950-j7m69833 97 2 , , , cord-286950-j7m69833 97 3 the the DT cord-286950-j7m69833 97 4 risks risk NNS cord-286950-j7m69833 97 5 of of IN cord-286950-j7m69833 97 6 the the DT cord-286950-j7m69833 97 7 democratization democratization NN cord-286950-j7m69833 97 8 of of IN cord-286950-j7m69833 97 9 CRISPR CRISPR NNP cord-286950-j7m69833 97 10 / / SYM cord-286950-j7m69833 97 11 Cas9 Cas9 NNP cord-286950-j7m69833 97 12 technology technology NN cord-286950-j7m69833 97 13 go go VBP cord-286950-j7m69833 97 14 well well RB cord-286950-j7m69833 97 15 beyond beyond IN cord-286950-j7m69833 97 16 GOF GOF NNP cord-286950-j7m69833 97 17 research research NN cord-286950-j7m69833 97 18 , , , cord-286950-j7m69833 97 19 and and CC cord-286950-j7m69833 97 20 there there EX cord-286950-j7m69833 97 21 has have VBZ cord-286950-j7m69833 97 22 been be VBN cord-286950-j7m69833 97 23 a a DT cord-286950-j7m69833 97 24 call call NN cord-286950-j7m69833 97 25 for for IN cord-286950-j7m69833 97 26 a a DT cord-286950-j7m69833 97 27 much much RB cord-286950-j7m69833 97 28 more more RBR cord-286950-j7m69833 97 29 concerted concerted JJ cord-286950-j7m69833 97 30 , , , cord-286950-j7m69833 97 31 international international JJ cord-286950-j7m69833 97 32 , , , cord-286950-j7m69833 97 33 public public JJ cord-286950-j7m69833 97 34 debate debate NN cord-286950-j7m69833 97 35 about about IN cord-286950-j7m69833 97 36 monitoring monitoring NN cord-286950-j7m69833 97 37 and and CC cord-286950-j7m69833 97 38 possibly possibly RB cord-286950-j7m69833 97 39 regulating regulate VBG cord-286950-j7m69833 97 40 access access NN cord-286950-j7m69833 97 41 to to IN cord-286950-j7m69833 97 42 some some DT cord-286950-j7m69833 97 43 of of IN cord-286950-j7m69833 97 44 those those DT cord-286950-j7m69833 97 45 tools tool NNS cord-286950-j7m69833 97 46 [ [ -LRB- cord-286950-j7m69833 97 47 see see VB cord-286950-j7m69833 97 48 31 31 CD cord-286950-j7m69833 97 49 ] ] -RRB- cord-286950-j7m69833 97 50 . . . cord-286950-j7m69833 98 1 Given give VBN cord-286950-j7m69833 98 2 these these DT cord-286950-j7m69833 98 3 difficulties difficulty NNS cord-286950-j7m69833 98 4 , , , cord-286950-j7m69833 98 5 what what WP cord-286950-j7m69833 98 6 is be VBZ cord-286950-j7m69833 98 7 the the DT cord-286950-j7m69833 98 8 responsible responsible JJ cord-286950-j7m69833 98 9 way way NN cord-286950-j7m69833 98 10 for for IN cord-286950-j7m69833 98 11 GOF GOF NNP cord-286950-j7m69833 98 12 researchers researcher NNS cord-286950-j7m69833 98 13 to to TO cord-286950-j7m69833 98 14 proceed proceed VB cord-286950-j7m69833 98 15 with with IN cord-286950-j7m69833 98 16 respect respect NN cord-286950-j7m69833 98 17 to to IN cord-286950-j7m69833 98 18 potential potential JJ cord-286950-j7m69833 98 19 misuse misuse NN cord-286950-j7m69833 98 20 ? ? . cord-286950-j7m69833 99 1 This this DT cord-286950-j7m69833 99 2 is be VBZ cord-286950-j7m69833 99 3 a a DT cord-286950-j7m69833 99 4 place place NN cord-286950-j7m69833 99 5 where where WRB cord-286950-j7m69833 99 6 prudence prudence NN cord-286950-j7m69833 99 7 might may MD cord-286950-j7m69833 99 8 be be VB cord-286950-j7m69833 99 9 a a DT cord-286950-j7m69833 99 10 better well JJR cord-286950-j7m69833 99 11 guide guide NN cord-286950-j7m69833 99 12 than than IN cord-286950-j7m69833 99 13 cost cost NN cord-286950-j7m69833 99 14 - - HYPH cord-286950-j7m69833 99 15 benefit benefit NN cord-286950-j7m69833 99 16 analysis analysis NN cord-286950-j7m69833 99 17 . . . cord-286950-j7m69833 100 1 Thus thus RB cord-286950-j7m69833 100 2 , , , cord-286950-j7m69833 100 3 one one CD cord-286950-j7m69833 100 4 notes note VBZ cord-286950-j7m69833 100 5 that that IN cord-286950-j7m69833 100 6 , , , cord-286950-j7m69833 100 7 for for IN cord-286950-j7m69833 100 8 the the DT cord-286950-j7m69833 100 9 researcher researcher NN cord-286950-j7m69833 100 10 's 's POS cord-286950-j7m69833 100 11 own own JJ cord-286950-j7m69833 100 12 safety safety NN cord-286950-j7m69833 100 13 , , , cord-286950-j7m69833 100 14 GOF GOF NNP cord-286950-j7m69833 100 15 research research NN cord-286950-j7m69833 100 16 with with IN cord-286950-j7m69833 100 17 especially especially RB cord-286950-j7m69833 100 18 dangerous dangerous JJ cord-286950-j7m69833 100 19 pathogens pathogen NNS cord-286950-j7m69833 100 20 must must MD cord-286950-j7m69833 100 21 be be VB cord-286950-j7m69833 100 22 done do VBN cord-286950-j7m69833 100 23 in in IN cord-286950-j7m69833 100 24 labs lab NNS cord-286950-j7m69833 100 25 with with IN cord-286950-j7m69833 100 26 very very RB cord-286950-j7m69833 100 27 high high JJ cord-286950-j7m69833 100 28 biosafety biosafety NN cord-286950-j7m69833 100 29 standards standard NNS cord-286950-j7m69833 100 30 , , , cord-286950-j7m69833 100 31 at at IN cord-286950-j7m69833 100 32 least least JJS cord-286950-j7m69833 100 33 biosafety biosafety NN cord-286950-j7m69833 100 34 level level NN cord-286950-j7m69833 100 35 ( ( -LRB- cord-286950-j7m69833 100 36 BSL)-3 bsl)-3 NN cord-286950-j7m69833 100 37 . . . cord-286950-j7m69833 101 1 That that DT cord-286950-j7m69833 101 2 means mean VBZ cord-286950-j7m69833 101 3 that that IN cord-286950-j7m69833 101 4 , , , cord-286950-j7m69833 101 5 except except IN cord-286950-j7m69833 101 6 for for IN cord-286950-j7m69833 101 7 the the DT cord-286950-j7m69833 101 8 rare rare JJ cord-286950-j7m69833 101 9 suicidal suicidal JJ cord-286950-j7m69833 101 10 individual individual NN cord-286950-j7m69833 101 11 , , , cord-286950-j7m69833 101 12 such such JJ cord-286950-j7m69833 101 13 research research NN cord-286950-j7m69833 101 14 will will MD cord-286950-j7m69833 101 15 only only RB cord-286950-j7m69833 101 16 be be VB cord-286950-j7m69833 101 17 feasible feasible JJ cord-286950-j7m69833 101 18 in in IN cord-286950-j7m69833 101 19 countries country NNS cord-286950-j7m69833 101 20 with with IN cord-286950-j7m69833 101 21 the the DT cord-286950-j7m69833 101 22 necessary necessary JJ cord-286950-j7m69833 101 23 biosafety biosafety NN cord-286950-j7m69833 101 24 facilities facility NNS cord-286950-j7m69833 101 25 and and CC cord-286950-j7m69833 101 26 protocols protocol NNS cord-286950-j7m69833 101 27 , , , cord-286950-j7m69833 101 28 and and CC cord-286950-j7m69833 101 29 the the DT cord-286950-j7m69833 101 30 list list NN cord-286950-j7m69833 101 31 of of IN cord-286950-j7m69833 101 32 such such JJ cord-286950-j7m69833 101 33 facilities facility NNS cord-286950-j7m69833 101 34 today today NN cord-286950-j7m69833 101 35 includes include VBZ cord-286950-j7m69833 101 36 mostly mostly RB cord-286950-j7m69833 101 37 nations nation NNS cord-286950-j7m69833 101 38 with with IN cord-286950-j7m69833 101 39 proven prove VBN cord-286950-j7m69833 101 40 records record NNS cord-286950-j7m69833 101 41 of of IN cord-286950-j7m69833 101 42 responsible responsible JJ cord-286950-j7m69833 101 43 research research NN cord-286950-j7m69833 101 44 conduct conduct NN cord-286950-j7m69833 101 45 , , , cord-286950-j7m69833 101 46 nations nation NNS cord-286950-j7m69833 101 47 which which WDT cord-286950-j7m69833 101 48 also also RB cord-286950-j7m69833 101 49 have have VBP cord-286950-j7m69833 101 50 the the DT cord-286950-j7m69833 101 51 technical technical JJ cord-286950-j7m69833 101 52 expertise expertise NN cord-286950-j7m69833 101 53 to to TO cord-286950-j7m69833 101 54 conduct conduct VB cord-286950-j7m69833 101 55 such such JJ cord-286950-j7m69833 101 56 research research NN cord-286950-j7m69833 101 57 entirely entirely RB cord-286950-j7m69833 101 58 on on IN cord-286950-j7m69833 101 59 their -PRON- PRP$ cord-286950-j7m69833 101 60 own own JJ cord-286950-j7m69833 101 61 . . . cord-286950-j7m69833 102 1 Of of RB cord-286950-j7m69833 102 2 course course RB cord-286950-j7m69833 102 3 one one PRP cord-286950-j7m69833 102 4 could could MD cord-286950-j7m69833 102 5 imagine imagine VB cord-286950-j7m69833 102 6 a a DT cord-286950-j7m69833 102 7 nation nation NN cord-286950-j7m69833 102 8 like like IN cord-286950-j7m69833 102 9 North North NNP cord-286950-j7m69833 102 10 Korea Korea NNP cord-286950-j7m69833 102 11 aspiring aspire VBG cord-286950-j7m69833 102 12 to to IN cord-286950-j7m69833 102 13 a a DT cord-286950-j7m69833 102 14 bioweapon bioweapon NN cord-286950-j7m69833 102 15 capability capability NN cord-286950-j7m69833 102 16 , , , cord-286950-j7m69833 102 17 and and CC cord-286950-j7m69833 102 18 as as IN cord-286950-j7m69833 102 19 they -PRON- PRP cord-286950-j7m69833 102 20 have have VBP cord-286950-j7m69833 102 21 demonstrated demonstrate VBN cord-286950-j7m69833 102 22 with with IN cord-286950-j7m69833 102 23 their -PRON- PRP$ cord-286950-j7m69833 102 24 successes success NNS cord-286950-j7m69833 102 25 in in IN cord-286950-j7m69833 102 26 offensive offensive JJ cord-286950-j7m69833 102 27 cyber cyber JJ cord-286950-j7m69833 102 28 operations operation NNS cord-286950-j7m69833 102 29 , , , cord-286950-j7m69833 102 30 ballistic ballistic JJ cord-286950-j7m69833 102 31 missiles missile NNS cord-286950-j7m69833 102 32 , , , cord-286950-j7m69833 102 33 and and CC cord-286950-j7m69833 102 34 nuclear nuclear JJ cord-286950-j7m69833 102 35 weapons weapon NNS cord-286950-j7m69833 102 36 , , , cord-286950-j7m69833 102 37 there there EX cord-286950-j7m69833 102 38 is be VBZ cord-286950-j7m69833 102 39 no no DT cord-286950-j7m69833 102 40 lack lack NN cord-286950-j7m69833 102 41 of of IN cord-286950-j7m69833 102 42 technical technical JJ cord-286950-j7m69833 102 43 talent talent NN cord-286950-j7m69833 102 44 in in IN cord-286950-j7m69833 102 45 North North NNP cord-286950-j7m69833 102 46 Korea Korea NNP cord-286950-j7m69833 102 47 . . . cord-286950-j7m69833 103 1 For for IN cord-286950-j7m69833 103 2 all all DT cord-286950-j7m69833 103 3 of of IN cord-286950-j7m69833 103 4 these these DT cord-286950-j7m69833 103 5 reasons reason NNS cord-286950-j7m69833 103 6 , , , cord-286950-j7m69833 103 7 the the DT cord-286950-j7m69833 103 8 risk risk NN cord-286950-j7m69833 103 9 of of IN cord-286950-j7m69833 103 10 publication publication NN cord-286950-j7m69833 103 11 of of IN cord-286950-j7m69833 103 12 GOF GOF NNP cord-286950-j7m69833 103 13 research research NN cord-286950-j7m69833 103 14 related relate VBN cord-286950-j7m69833 103 15 to to IN cord-286950-j7m69833 103 16 misuse misuse NN cord-286950-j7m69833 103 17 of of IN cord-286950-j7m69833 103 18 biotechnology biotechnology NN cord-286950-j7m69833 103 19 seems seem VBZ cord-286950-j7m69833 103 20 to to TO cord-286950-j7m69833 103 21 have have VB cord-286950-j7m69833 103 22 receded recede VBN cord-286950-j7m69833 103 23 from from IN cord-286950-j7m69833 103 24 the the DT cord-286950-j7m69833 103 25 forefront forefront NN cord-286950-j7m69833 103 26 of of IN cord-286950-j7m69833 103 27 concern concern NN cord-286950-j7m69833 103 28 . . . cord-286950-j7m69833 104 1 In in IN cord-286950-j7m69833 104 2 addition addition NN cord-286950-j7m69833 104 3 , , , cord-286950-j7m69833 104 4 the the DT cord-286950-j7m69833 104 5 scientific scientific JJ cord-286950-j7m69833 104 6 publishing publishing NN cord-286950-j7m69833 104 7 community community NN cord-286950-j7m69833 104 8 is be VBZ cord-286950-j7m69833 104 9 much much RB cord-286950-j7m69833 104 10 more more RBR cord-286950-j7m69833 104 11 aware aware JJ cord-286950-j7m69833 104 12 of of IN cord-286950-j7m69833 104 13 these these DT cord-286950-j7m69833 104 14 issues issue NNS cord-286950-j7m69833 104 15 , , , cord-286950-j7m69833 104 16 and and CC cord-286950-j7m69833 104 17 many many JJ cord-286950-j7m69833 104 18 journals journal NNS cord-286950-j7m69833 104 19 have have VBP cord-286950-j7m69833 104 20 instituted institute VBN cord-286950-j7m69833 104 21 internal internal JJ cord-286950-j7m69833 104 22 reviews review NNS cord-286950-j7m69833 104 23 for for IN cord-286950-j7m69833 104 24 papers paper NNS cord-286950-j7m69833 104 25 that that WDT cord-286950-j7m69833 104 26 include include VBP cord-286950-j7m69833 104 27 DURC DURC NNP cord-286950-j7m69833 104 28 [ [ -LRB- cord-286950-j7m69833 104 29 e.g. e.g. RB cord-286950-j7m69833 104 30 , , , cord-286950-j7m69833 104 31 32 32 CD cord-286950-j7m69833 104 32 , , , cord-286950-j7m69833 104 33 33 33 CD cord-286950-j7m69833 104 34 ] ] -RRB- cord-286950-j7m69833 104 35 . . . cord-286950-j7m69833 105 1 The the DT cord-286950-j7m69833 105 2 more more RBR cord-286950-j7m69833 105 3 prominent prominent JJ cord-286950-j7m69833 105 4 worry worry NN cord-286950-j7m69833 105 5 today today NN cord-286950-j7m69833 105 6 is be VBZ cord-286950-j7m69833 105 7 about about IN cord-286950-j7m69833 105 8 accidently accidently RB cord-286950-j7m69833 105 9 unleashing unleash VBG cord-286950-j7m69833 105 10 the the DT cord-286950-j7m69833 105 11 very very JJ cord-286950-j7m69833 105 12 kind kind NN cord-286950-j7m69833 105 13 of of IN cord-286950-j7m69833 105 14 global global JJ cord-286950-j7m69833 105 15 pandemic pandemic NN cord-286950-j7m69833 105 16 that that WDT cord-286950-j7m69833 105 17 one one PRP cord-286950-j7m69833 105 18 was be VBD cord-286950-j7m69833 105 19 seeking seek VBG cord-286950-j7m69833 105 20 to to TO cord-286950-j7m69833 105 21 prevent prevent VB cord-286950-j7m69833 105 22 . . . cord-286950-j7m69833 106 1 A a DT cord-286950-j7m69833 106 2 number number NN cord-286950-j7m69833 106 3 of of IN cord-286950-j7m69833 106 4 critics critic NNS cord-286950-j7m69833 106 5 have have VBP cord-286950-j7m69833 106 6 argued argue VBN cord-286950-j7m69833 106 7 that that IN cord-286950-j7m69833 106 8 the the DT cord-286950-j7m69833 106 9 risk risk NN cord-286950-j7m69833 106 10 of of IN cord-286950-j7m69833 106 11 inadvertently inadvertently RB cord-286950-j7m69833 106 12 creating create VBG cord-286950-j7m69833 106 13 a a DT cord-286950-j7m69833 106 14 global global JJ cord-286950-j7m69833 106 15 pandemic pandemic NN cord-286950-j7m69833 106 16 through through IN cord-286950-j7m69833 106 17 accidental accidental JJ cord-286950-j7m69833 106 18 release release NN cord-286950-j7m69833 106 19 of of IN cord-286950-j7m69833 106 20 an an DT cord-286950-j7m69833 106 21 engineered engineered JJ cord-286950-j7m69833 106 22 , , , cord-286950-j7m69833 106 23 human human JJ cord-286950-j7m69833 106 24 - - HYPH cord-286950-j7m69833 106 25 transmissible transmissible JJ cord-286950-j7m69833 106 26 pathogen pathogen NN cord-286950-j7m69833 106 27 with with IN cord-286950-j7m69833 106 28 high high JJ cord-286950-j7m69833 106 29 virulence virulence NN cord-286950-j7m69833 106 30 and and CC cord-286950-j7m69833 106 31 case case NN cord-286950-j7m69833 106 32 fatality fatality NN cord-286950-j7m69833 106 33 rate rate NN cord-286950-j7m69833 106 34 vastly vastly RB cord-286950-j7m69833 106 35 outweighs outweigh VBZ cord-286950-j7m69833 106 36 any any DT cord-286950-j7m69833 106 37 benefits benefit NNS cord-286950-j7m69833 106 38 that that WDT cord-286950-j7m69833 106 39 might may MD cord-286950-j7m69833 106 40 be be VB cord-286950-j7m69833 106 41 obtained obtain VBN cord-286950-j7m69833 106 42 from from IN cord-286950-j7m69833 106 43 such such JJ cord-286950-j7m69833 106 44 research research NN cord-286950-j7m69833 106 45 [ [ -LRB- cord-286950-j7m69833 106 46 e.g. e.g. RB cord-286950-j7m69833 106 47 , , , cord-286950-j7m69833 106 48 34 34 CD cord-286950-j7m69833 106 49 ] ] -RRB- cord-286950-j7m69833 106 50 . . . cord-286950-j7m69833 107 1 Thus thus RB cord-286950-j7m69833 107 2 , , , cord-286950-j7m69833 107 3 one one CD cord-286950-j7m69833 107 4 source source NN cord-286950-j7m69833 107 5 claims claim VBZ cord-286950-j7m69833 107 6 a a DT cord-286950-j7m69833 107 7 0.01 0.01 CD cord-286950-j7m69833 107 8 % % NN cord-286950-j7m69833 107 9 to to TO cord-286950-j7m69833 107 10 0.1 0.1 CD cord-286950-j7m69833 107 11 % % NN cord-286950-j7m69833 107 12 probability probability NN cord-286950-j7m69833 107 13 per per IN cord-286950-j7m69833 107 14 year year NN cord-286950-j7m69833 107 15 of of IN cord-286950-j7m69833 107 16 research research NN cord-286950-j7m69833 107 17 in in IN cord-286950-j7m69833 107 18 a a DT cord-286950-j7m69833 107 19 BSL-3 BSL-3 NNP cord-286950-j7m69833 107 20 lab lab NN cord-286950-j7m69833 107 21 of of IN cord-286950-j7m69833 107 22 an an DT cord-286950-j7m69833 107 23 accidental accidental JJ cord-286950-j7m69833 107 24 release release NN cord-286950-j7m69833 107 25 of of IN cord-286950-j7m69833 107 26 highly highly RB cord-286950-j7m69833 107 27 transmissible transmissible JJ cord-286950-j7m69833 107 28 influenza influenza NN cord-286950-j7m69833 107 29 virus virus NN cord-286950-j7m69833 107 30 that that WDT cord-286950-j7m69833 107 31 would would MD cord-286950-j7m69833 107 32 kill kill VB cord-286950-j7m69833 107 33 between between IN cord-286950-j7m69833 107 34 200,000 200,000 CD cord-286950-j7m69833 107 35 and and CC cord-286950-j7m69833 107 36 16 16 CD cord-286950-j7m69833 107 37 million million CD cord-286950-j7m69833 107 38 people people NNS cord-286950-j7m69833 107 39 [ [ -LRB- cord-286950-j7m69833 107 40 35 35 CD cord-286950-j7m69833 107 41 , , , cord-286950-j7m69833 107 42 36 36 CD cord-286950-j7m69833 107 43 ] ] -RRB- cord-286950-j7m69833 107 44 . . . cord-286950-j7m69833 108 1 If if IN cord-286950-j7m69833 108 2 this this DT cord-286950-j7m69833 108 3 is be VBZ cord-286950-j7m69833 108 4 a a DT cord-286950-j7m69833 108 5 reliable reliable JJ cord-286950-j7m69833 108 6 estimate estimate NN cord-286950-j7m69833 108 7 , , , cord-286950-j7m69833 108 8 that that DT cord-286950-j7m69833 108 9 's be VBZ cord-286950-j7m69833 108 10 a a DT cord-286950-j7m69833 108 11 scary scary JJ cord-286950-j7m69833 108 12 prospect prospect NN cord-286950-j7m69833 108 13 . . . cord-286950-j7m69833 109 1 On on IN cord-286950-j7m69833 109 2 the the DT cord-286950-j7m69833 109 3 other other JJ cord-286950-j7m69833 109 4 hand hand NN cord-286950-j7m69833 109 5 , , , cord-286950-j7m69833 109 6 one one CD cord-286950-j7m69833 109 7 of of IN cord-286950-j7m69833 109 8 the the DT cord-286950-j7m69833 109 9 authors author NNS cord-286950-j7m69833 109 10 of of IN cord-286950-j7m69833 109 11 the the DT cord-286950-j7m69833 109 12 original original JJ cord-286950-j7m69833 109 13 H5N1 H5N1 NNP cord-286950-j7m69833 109 14 studies study NNS cord-286950-j7m69833 109 15 has have VBZ cord-286950-j7m69833 109 16 calculated calculate VBN cord-286950-j7m69833 109 17 the the DT cord-286950-j7m69833 109 18 risks risk NNS cord-286950-j7m69833 109 19 to to TO cord-286950-j7m69833 109 20 be be VB cord-286950-j7m69833 109 21 much much JJ cord-286950-j7m69833 109 22 , , , cord-286950-j7m69833 109 23 much much RB cord-286950-j7m69833 109 24 lower low JJR cord-286950-j7m69833 109 25 [ [ -LRB- cord-286950-j7m69833 109 26 37 37 CD cord-286950-j7m69833 109 27 ] ] -RRB- cord-286950-j7m69833 109 28 . . . cord-286950-j7m69833 110 1 Given give VBN cord-286950-j7m69833 110 2 a a DT cord-286950-j7m69833 110 3 claimed claim VBN cord-286950-j7m69833 110 4 risk risk NN cord-286950-j7m69833 110 5 on on IN cord-286950-j7m69833 110 6 that that DT cord-286950-j7m69833 110 7 high high JJ cord-286950-j7m69833 110 8 a a DT cord-286950-j7m69833 110 9 scale scale NN cord-286950-j7m69833 110 10 , , , cord-286950-j7m69833 110 11 how how WRB cord-286950-j7m69833 110 12 shall shall MD cord-286950-j7m69833 110 13 we -PRON- PRP cord-286950-j7m69833 110 14 think think VB cord-286950-j7m69833 110 15 about about IN cord-286950-j7m69833 110 16 the the DT cord-286950-j7m69833 110 17 balance balance NN cord-286950-j7m69833 110 18 between between IN cord-286950-j7m69833 110 19 benefit benefit NN cord-286950-j7m69833 110 20 and and CC cord-286950-j7m69833 110 21 risk risk NN cord-286950-j7m69833 110 22 ? ? . cord-286950-j7m69833 111 1 First first RB cord-286950-j7m69833 111 2 , , , cord-286950-j7m69833 111 3 we -PRON- PRP cord-286950-j7m69833 111 4 must must MD cord-286950-j7m69833 111 5 ask ask VB cord-286950-j7m69833 111 6 some some DT cord-286950-j7m69833 111 7 tough tough JJ cord-286950-j7m69833 111 8 questions question NNS cord-286950-j7m69833 111 9 about about IN cord-286950-j7m69833 111 10 the the DT cord-286950-j7m69833 111 11 risk risk NN cord-286950-j7m69833 111 12 analysis analysis NN cord-286950-j7m69833 111 13 itself -PRON- PRP cord-286950-j7m69833 111 14 . . . cord-286950-j7m69833 112 1 Many many JJ cord-286950-j7m69833 112 2 factors factor NNS cord-286950-j7m69833 112 3 go go VBP cord-286950-j7m69833 112 4 into into IN cord-286950-j7m69833 112 5 such such PDT cord-286950-j7m69833 112 6 an an DT cord-286950-j7m69833 112 7 analysis analysis NN cord-286950-j7m69833 112 8 , , , cord-286950-j7m69833 112 9 including include VBG cord-286950-j7m69833 112 10 historical historical JJ cord-286950-j7m69833 112 11 data datum NNS cord-286950-j7m69833 112 12 on on IN cord-286950-j7m69833 112 13 accidental accidental JJ cord-286950-j7m69833 112 14 exposure exposure NN cord-286950-j7m69833 112 15 in in IN cord-286950-j7m69833 112 16 BSL-3 BSL-3 NNP cord-286950-j7m69833 112 17 and and CC cord-286950-j7m69833 112 18 BSL-4 BSL-4 NNP cord-286950-j7m69833 112 19 labs lab NNS cord-286950-j7m69833 112 20 and and CC cord-286950-j7m69833 112 21 simulation simulation NN cord-286950-j7m69833 112 22 studies study NNS cord-286950-j7m69833 112 23 of of IN cord-286950-j7m69833 112 24 disease disease NNP cord-286950-j7m69833 112 25 spread spread VBD cord-286950-j7m69833 112 26 after after IN cord-286950-j7m69833 112 27 accidental accidental JJ cord-286950-j7m69833 112 28 exposure exposure NN cord-286950-j7m69833 112 29 . . . cord-286950-j7m69833 113 1 We -PRON- PRP cord-286950-j7m69833 113 2 consider consider VBP cord-286950-j7m69833 113 3 each each DT cord-286950-j7m69833 113 4 of of IN cord-286950-j7m69833 113 5 these these DT cord-286950-j7m69833 113 6 factors factor NNS cord-286950-j7m69833 113 7 separately separately RB cord-286950-j7m69833 113 8 . . . cord-286950-j7m69833 114 1 To to IN cord-286950-j7m69833 114 2 date date NN cord-286950-j7m69833 114 3 , , , cord-286950-j7m69833 114 4 only only RB cord-286950-j7m69833 114 5 one one CD cord-286950-j7m69833 114 6 reasonably reasonably RB cord-286950-j7m69833 114 7 sophisticated sophisticated JJ cord-286950-j7m69833 114 8 simulation simulation NN cord-286950-j7m69833 114 9 study study NN cord-286950-j7m69833 114 10 for for IN cord-286950-j7m69833 114 11 the the DT cord-286950-j7m69833 114 12 spread spread NN cord-286950-j7m69833 114 13 of of IN cord-286950-j7m69833 114 14 a a DT cord-286950-j7m69833 114 15 potentially potentially RB cord-286950-j7m69833 114 16 pandemic pandemic JJ cord-286950-j7m69833 114 17 influenza influenza NN cord-286950-j7m69833 114 18 virus virus NN cord-286950-j7m69833 114 19 has have VBZ cord-286950-j7m69833 114 20 been be VBN cord-286950-j7m69833 114 21 reported report VBN cord-286950-j7m69833 114 22 [ [ -LRB- cord-286950-j7m69833 114 23 38 38 CD cord-286950-j7m69833 114 24 ] ] -RRB- cord-286950-j7m69833 114 25 . . . cord-286950-j7m69833 115 1 This this DT cord-286950-j7m69833 115 2 is be VBZ cord-286950-j7m69833 115 3 the the DT cord-286950-j7m69833 115 4 study study NN cord-286950-j7m69833 115 5 cited cite VBN cord-286950-j7m69833 115 6 by by IN cord-286950-j7m69833 115 7 Lipsitch Lipsitch NNP cord-286950-j7m69833 115 8 and and CC cord-286950-j7m69833 115 9 Inglesbsy Inglesbsy NNP cord-286950-j7m69833 115 10 [ [ -LRB- cord-286950-j7m69833 115 11 35 35 CD cord-286950-j7m69833 115 12 , , , cord-286950-j7m69833 115 13 36 36 CD cord-286950-j7m69833 115 14 ] ] -RRB- cord-286950-j7m69833 115 15 . . . cord-286950-j7m69833 116 1 The the DT cord-286950-j7m69833 116 2 researchers researcher NNS cord-286950-j7m69833 116 3 who who WP cord-286950-j7m69833 116 4 conducted conduct VBD cord-286950-j7m69833 116 5 the the DT cord-286950-j7m69833 116 6 simulation simulation NN cord-286950-j7m69833 116 7 study study NN cord-286950-j7m69833 116 8 had have VBD cord-286950-j7m69833 116 9 to to TO cord-286950-j7m69833 116 10 make make VB cord-286950-j7m69833 116 11 many many JJ cord-286950-j7m69833 116 12 assumptions assumption NNS cord-286950-j7m69833 116 13 about about IN cord-286950-j7m69833 116 14 such such JJ cord-286950-j7m69833 116 15 variables variable NNS cord-286950-j7m69833 116 16 as as IN cord-286950-j7m69833 116 17 virulence virulence NN cord-286950-j7m69833 116 18 , , , cord-286950-j7m69833 116 19 case case NN cord-286950-j7m69833 116 20 fatality fatality NN cord-286950-j7m69833 116 21 rate rate NN cord-286950-j7m69833 116 22 , , , cord-286950-j7m69833 116 23 latency latency NN cord-286950-j7m69833 116 24 time time NN cord-286950-j7m69833 116 25 , , , cord-286950-j7m69833 116 26 demographics demographic NNS cord-286950-j7m69833 116 27 , , , cord-286950-j7m69833 116 28 geography geography NN cord-286950-j7m69833 116 29 , , , cord-286950-j7m69833 116 30 response response NN cord-286950-j7m69833 116 31 capabilities capability NNS cord-286950-j7m69833 116 32 of of IN cord-286950-j7m69833 116 33 public public JJ cord-286950-j7m69833 116 34 health health NN cord-286950-j7m69833 116 35 authorities authority NNS cord-286950-j7m69833 116 36 , , , cord-286950-j7m69833 116 37 and and CC cord-286950-j7m69833 116 38 monitoring monitoring NN cord-286950-j7m69833 116 39 of of IN cord-286950-j7m69833 116 40 lab lab NN cord-286950-j7m69833 116 41 personnel personnel NNS cord-286950-j7m69833 116 42 for for IN cord-286950-j7m69833 116 43 symptoms symptom NNS cord-286950-j7m69833 116 44 of of IN cord-286950-j7m69833 116 45 exposure exposure NN cord-286950-j7m69833 116 46 . . . cord-286950-j7m69833 117 1 The the DT cord-286950-j7m69833 117 2 simulation simulation NN cord-286950-j7m69833 117 3 model model NN cord-286950-j7m69833 117 4 was be VBD cord-286950-j7m69833 117 5 robust robust JJ cord-286950-j7m69833 117 6 against against IN cord-286950-j7m69833 117 7 variations variation NNS cord-286950-j7m69833 117 8 in in IN cord-286950-j7m69833 117 9 many many JJ cord-286950-j7m69833 117 10 of of IN cord-286950-j7m69833 117 11 these these DT cord-286950-j7m69833 117 12 parameters parameter NNS cord-286950-j7m69833 117 13 , , , cord-286950-j7m69833 117 14 but but CC cord-286950-j7m69833 117 15 there there EX cord-286950-j7m69833 117 16 were be VBD cord-286950-j7m69833 117 17 considerable considerable JJ cord-286950-j7m69833 117 18 differences difference NNS cord-286950-j7m69833 117 19 in in IN cord-286950-j7m69833 117 20 outcome outcome NN cord-286950-j7m69833 117 21 with with IN cord-286950-j7m69833 117 22 some some DT cord-286950-j7m69833 117 23 variations variation NNS cord-286950-j7m69833 117 24 , , , cord-286950-j7m69833 117 25 such such JJ cord-286950-j7m69833 117 26 as as IN cord-286950-j7m69833 117 27 early early JJ cord-286950-j7m69833 117 28 detection detection NN cord-286950-j7m69833 117 29 of of IN cord-286950-j7m69833 117 30 initial initial JJ cord-286950-j7m69833 117 31 exposure exposure NN cord-286950-j7m69833 117 32 . . . cord-286950-j7m69833 118 1 Still still RB cord-286950-j7m69833 118 2 , , , cord-286950-j7m69833 118 3 on on IN cord-286950-j7m69833 118 4 the the DT cord-286950-j7m69833 118 5 whole whole NN cord-286950-j7m69833 118 6 , , , cord-286950-j7m69833 118 7 the the DT cord-286950-j7m69833 118 8 numbers number NNS cord-286950-j7m69833 118 9 are be VBP cord-286950-j7m69833 118 10 grim grim JJ cord-286950-j7m69833 118 11 . . . cord-286950-j7m69833 119 1 With with IN cord-286950-j7m69833 119 2 the the DT cord-286950-j7m69833 119 3 right right JJ cord-286950-j7m69833 119 4 combination combination NN cord-286950-j7m69833 119 5 of of IN cord-286950-j7m69833 119 6 factors factor NNS cord-286950-j7m69833 119 7 , , , cord-286950-j7m69833 119 8 it -PRON- PRP cord-286950-j7m69833 119 9 is be VBZ cord-286950-j7m69833 119 10 theoretically theoretically RB cord-286950-j7m69833 119 11 possible possible JJ cord-286950-j7m69833 119 12 for for IN cord-286950-j7m69833 119 13 an an DT cord-286950-j7m69833 119 14 accidental accidental JJ cord-286950-j7m69833 119 15 release release NN cord-286950-j7m69833 119 16 to to TO cord-286950-j7m69833 119 17 wreak wreak VB cord-286950-j7m69833 119 18 havoc havoc NN cord-286950-j7m69833 119 19 . . . cord-286950-j7m69833 120 1 That that DT cord-286950-j7m69833 120 2 brings bring VBZ cord-286950-j7m69833 120 3 us -PRON- PRP cord-286950-j7m69833 120 4 to to IN cord-286950-j7m69833 120 5 the the DT cord-286950-j7m69833 120 6 question question NN cord-286950-j7m69833 120 7 of of IN cord-286950-j7m69833 120 8 how how WRB cord-286950-j7m69833 120 9 probable probable JJ cord-286950-j7m69833 120 10 such such PDT cord-286950-j7m69833 120 11 a a DT cord-286950-j7m69833 120 12 catastrophic catastrophic JJ cord-286950-j7m69833 120 13 event event NN cord-286950-j7m69833 120 14 is be VBZ cord-286950-j7m69833 120 15 and and CC cord-286950-j7m69833 120 16 the the DT cord-286950-j7m69833 120 17 science science NN cord-286950-j7m69833 120 18 of of IN cord-286950-j7m69833 120 19 risk risk NN cord-286950-j7m69833 120 20 - - HYPH cord-286950-j7m69833 120 21 benefit benefit NN cord-286950-j7m69833 120 22 analysis analysis NN cord-286950-j7m69833 120 23 . . . cord-286950-j7m69833 121 1 The the DT cord-286950-j7m69833 121 2 other other JJ cord-286950-j7m69833 121 3 major major JJ cord-286950-j7m69833 121 4 component component NN cord-286950-j7m69833 121 5 of of IN cord-286950-j7m69833 121 6 the the DT cord-286950-j7m69833 121 7 risk risk NN cord-286950-j7m69833 121 8 calculation calculation NN cord-286950-j7m69833 121 9 - - : cord-286950-j7m69833 121 10 the the DT cord-286950-j7m69833 121 11 chance chance NN cord-286950-j7m69833 121 12 of of IN cord-286950-j7m69833 121 13 accidental accidental JJ cord-286950-j7m69833 121 14 exposure exposure NN cord-286950-j7m69833 121 15 or or CC cord-286950-j7m69833 121 16 release release NN cord-286950-j7m69833 121 17 - - : cord-286950-j7m69833 121 18 is be VBZ cord-286950-j7m69833 121 19 generally generally RB cord-286950-j7m69833 121 20 estimated estimate VBN cord-286950-j7m69833 121 21 on on IN cord-286950-j7m69833 121 22 the the DT cord-286950-j7m69833 121 23 basis basis NN cord-286950-j7m69833 121 24 of of IN cord-286950-j7m69833 121 25 historical historical JJ cord-286950-j7m69833 121 26 data datum NNS cord-286950-j7m69833 121 27 , , , cord-286950-j7m69833 121 28 which which WDT cord-286950-j7m69833 121 29 , , , cord-286950-j7m69833 121 30 with with IN cord-286950-j7m69833 121 31 its -PRON- PRP$ cord-286950-j7m69833 121 32 foibles foible NNS cord-286950-j7m69833 121 33 , , , cord-286950-j7m69833 121 34 is be VBZ cord-286950-j7m69833 121 35 far far RB cord-286950-j7m69833 121 36 less less RBR cord-286950-j7m69833 121 37 robust robust JJ cord-286950-j7m69833 121 38 . . . cord-286950-j7m69833 122 1 The the DT cord-286950-j7m69833 122 2 spate spate NN cord-286950-j7m69833 122 3 of of IN cord-286950-j7m69833 122 4 accidents accident NNS cord-286950-j7m69833 122 5 in in IN cord-286950-j7m69833 122 6 US US NNP cord-286950-j7m69833 122 7 BSL-3 BSL-3 NNP cord-286950-j7m69833 122 8 labs lab VBZ cord-286950-j7m69833 122 9 a a DT cord-286950-j7m69833 122 10 few few JJ cord-286950-j7m69833 122 11 years year NNS cord-286950-j7m69833 122 12 ago ago RB cord-286950-j7m69833 122 13 rightly rightly RB cord-286950-j7m69833 122 14 aroused arouse VBD cord-286950-j7m69833 122 15 concern concern NN cord-286950-j7m69833 122 16 among among IN cord-286950-j7m69833 122 17 experts expert NNS cord-286950-j7m69833 122 18 but but CC cord-286950-j7m69833 122 19 also also RB cord-286950-j7m69833 122 20 generated generate VBN cord-286950-j7m69833 122 21 in in IN cord-286950-j7m69833 122 22 the the DT cord-286950-j7m69833 122 23 public public JJ cord-286950-j7m69833 122 24 mind mind NN cord-286950-j7m69833 122 25 a a DT cord-286950-j7m69833 122 26 perception perception NN cord-286950-j7m69833 122 27 of of IN cord-286950-j7m69833 122 28 risk risk NN cord-286950-j7m69833 122 29 that that WDT cord-286950-j7m69833 122 30 might may MD cord-286950-j7m69833 122 31 not not RB cord-286950-j7m69833 122 32 accurately accurately RB cord-286950-j7m69833 122 33 represent represent VB cord-286950-j7m69833 122 34 the the DT cord-286950-j7m69833 122 35 current current JJ cord-286950-j7m69833 122 36 state state NN cord-286950-j7m69833 122 37 of of IN cord-286950-j7m69833 122 38 affairs affair NNS cord-286950-j7m69833 122 39 after after IN cord-286950-j7m69833 122 40 more more RBR cord-286950-j7m69833 122 41 stringent stringent JJ cord-286950-j7m69833 122 42 monitoring monitoring NN cord-286950-j7m69833 122 43 and and CC cord-286950-j7m69833 122 44 review review NN cord-286950-j7m69833 122 45 procedures procedure NNS cord-286950-j7m69833 122 46 were be VBD cord-286950-j7m69833 122 47 implemented implement VBN cord-286950-j7m69833 122 48 . . . cord-286950-j7m69833 123 1 The the DT cord-286950-j7m69833 123 2 annual annual JJ cord-286950-j7m69833 123 3 rate rate NN cord-286950-j7m69833 123 4 of of IN cord-286950-j7m69833 123 5 accidental accidental JJ cord-286950-j7m69833 123 6 exposure exposure NN cord-286950-j7m69833 123 7 today today NN cord-286950-j7m69833 123 8 could could MD cord-286950-j7m69833 123 9 easily easily RB cord-286950-j7m69833 123 10 be be VB cord-286950-j7m69833 123 11 ten ten CD cord-286950-j7m69833 123 12 to to IN cord-286950-j7m69833 123 13 one one CD cord-286950-j7m69833 123 14 hundred hundred CD cord-286950-j7m69833 123 15 times time NNS cord-286950-j7m69833 123 16 smaller small JJR cord-286950-j7m69833 123 17 than than IN cord-286950-j7m69833 123 18 it -PRON- PRP cord-286950-j7m69833 123 19 appeared appear VBD cord-286950-j7m69833 123 20 to to TO cord-286950-j7m69833 123 21 be be VB cord-286950-j7m69833 123 22 in in IN cord-286950-j7m69833 123 23 2013 2013 CD cord-286950-j7m69833 123 24 . . . cord-286950-j7m69833 124 1 Of of RB cord-286950-j7m69833 124 2 course course RB cord-286950-j7m69833 124 3 , , , cord-286950-j7m69833 124 4 200,000 200,000 CD cord-286950-j7m69833 124 5 to to TO cord-286950-j7m69833 124 6 16 16 CD cord-286950-j7m69833 124 7 million million CD cord-286950-j7m69833 124 8 deaths death NNS cord-286950-j7m69833 124 9 per per IN cord-286950-j7m69833 124 10 lab lab NN cord-286950-j7m69833 124 11 year year NN cord-286950-j7m69833 124 12 is be VBZ cord-286950-j7m69833 124 13 still still RB cord-286950-j7m69833 124 14 reason reason NN cord-286950-j7m69833 124 15 for for IN cord-286950-j7m69833 124 16 worry worry NN cord-286950-j7m69833 124 17 . . . cord-286950-j7m69833 125 1 But but CC cord-286950-j7m69833 125 2 then then RB cord-286950-j7m69833 125 3 there there EX cord-286950-j7m69833 125 4 are be VBP cord-286950-j7m69833 125 5 other other JJ cord-286950-j7m69833 125 6 factors factor NNS cord-286950-j7m69833 125 7 to to TO cord-286950-j7m69833 125 8 consider consider VB cord-286950-j7m69833 125 9 . . . cord-286950-j7m69833 126 1 The the DT cord-286950-j7m69833 126 2 reported report VBN cord-286950-j7m69833 126 3 accidental accidental JJ cord-286950-j7m69833 126 4 exposures exposure NNS cord-286950-j7m69833 126 5 aggregate aggregate JJ cord-286950-j7m69833 126 6 data datum NNS cord-286950-j7m69833 126 7 on on IN cord-286950-j7m69833 126 8 all all DT cord-286950-j7m69833 126 9 organisms organism NNS cord-286950-j7m69833 126 10 that that WDT cord-286950-j7m69833 126 11 require require VBP cord-286950-j7m69833 126 12 high high JJ cord-286950-j7m69833 126 13 levels level NNS cord-286950-j7m69833 126 14 of of IN cord-286950-j7m69833 126 15 biosafety biosafety NN cord-286950-j7m69833 126 16 containment containment NN cord-286950-j7m69833 126 17 . . . cord-286950-j7m69833 127 1 None none NN cord-286950-j7m69833 127 2 of of IN cord-286950-j7m69833 127 3 those those DT cord-286950-j7m69833 127 4 cases case NNS cord-286950-j7m69833 127 5 involved involve VBD cord-286950-j7m69833 127 6 GOF GOF NNP cord-286950-j7m69833 127 7 research research NN cord-286950-j7m69833 127 8 , , , cord-286950-j7m69833 127 9 and and CC cord-286950-j7m69833 127 10 , , , cord-286950-j7m69833 127 11 given give VBN cord-286950-j7m69833 127 12 the the DT cord-286950-j7m69833 127 13 attention attention NN cord-286950-j7m69833 127 14 being be VBG cord-286950-j7m69833 127 15 paid pay VBN cord-286950-j7m69833 127 16 to to IN cord-286950-j7m69833 127 17 GOF GOF NNP cord-286950-j7m69833 127 18 by by IN cord-286950-j7m69833 127 19 comparison comparison NN cord-286950-j7m69833 127 20 with with IN cord-286950-j7m69833 127 21 research research NN cord-286950-j7m69833 127 22 on on IN cord-286950-j7m69833 127 23 , , , cord-286950-j7m69833 127 24 say say UH cord-286950-j7m69833 127 25 , , , cord-286950-j7m69833 127 26 natural natural JJ cord-286950-j7m69833 127 27 pathogens pathogen NNS cord-286950-j7m69833 127 28 , , , cord-286950-j7m69833 127 29 it -PRON- PRP cord-286950-j7m69833 127 30 is be VBZ cord-286950-j7m69833 127 31 not not RB cord-286950-j7m69833 127 32 at at RB cord-286950-j7m69833 127 33 all all RB cord-286950-j7m69833 127 34 clear clear JJ cord-286950-j7m69833 127 35 that that IN cord-286950-j7m69833 127 36 we -PRON- PRP cord-286950-j7m69833 127 37 can can MD cord-286950-j7m69833 127 38 reasonably reasonably RB cord-286950-j7m69833 127 39 extrapolate extrapolate VB cord-286950-j7m69833 127 40 from from IN cord-286950-j7m69833 127 41 the the DT cord-286950-j7m69833 127 42 historical historical JJ cord-286950-j7m69833 127 43 data datum NNS cord-286950-j7m69833 127 44 on on IN cord-286950-j7m69833 127 45 accidental accidental JJ cord-286950-j7m69833 127 46 exposure exposure NN cord-286950-j7m69833 127 47 to to IN cord-286950-j7m69833 127 48 the the DT cord-286950-j7m69833 127 49 risk risk NN cord-286950-j7m69833 127 50 of of IN cord-286950-j7m69833 127 51 accidental accidental JJ cord-286950-j7m69833 127 52 exposure exposure NN cord-286950-j7m69833 127 53 or or CC cord-286950-j7m69833 127 54 release release NN cord-286950-j7m69833 127 55 in in IN cord-286950-j7m69833 127 56 GOF GOF NNP cord-286950-j7m69833 127 57 research research NN cord-286950-j7m69833 127 58 . . . cord-286950-j7m69833 128 1 There there EX cord-286950-j7m69833 128 2 are be VBP cord-286950-j7m69833 128 3 still still RB cord-286950-j7m69833 128 4 deeper deep JJR cord-286950-j7m69833 128 5 problems problem NNS cord-286950-j7m69833 128 6 with with IN cord-286950-j7m69833 128 7 a a DT cord-286950-j7m69833 128 8 cost cost NN cord-286950-j7m69833 128 9 - - HYPH cord-286950-j7m69833 128 10 benefit benefit NN cord-286950-j7m69833 128 11 approach approach NN cord-286950-j7m69833 128 12 to to TO cord-286950-j7m69833 128 13 assess assess VB cord-286950-j7m69833 128 14 the the DT cord-286950-j7m69833 128 15 ethics ethic NNS cord-286950-j7m69833 128 16 of of IN cord-286950-j7m69833 128 17 GOF GOF NNP cord-286950-j7m69833 128 18 research research NN cord-286950-j7m69833 128 19 . . . cord-286950-j7m69833 129 1 First first RB cord-286950-j7m69833 129 2 , , , cord-286950-j7m69833 129 3 assessing assess VBG cord-286950-j7m69833 129 4 the the DT cord-286950-j7m69833 129 5 risk risk NN cord-286950-j7m69833 129 6 of of IN cord-286950-j7m69833 129 7 accidental accidental JJ cord-286950-j7m69833 129 8 release release NN cord-286950-j7m69833 129 9 and and CC cord-286950-j7m69833 129 10 an an DT cord-286950-j7m69833 129 11 attendant attendant JJ cord-286950-j7m69833 129 12 global global JJ cord-286950-j7m69833 129 13 pandemic pandemic NN cord-286950-j7m69833 129 14 is be VBZ cord-286950-j7m69833 129 15 only only RB cord-286950-j7m69833 129 16 one one CD cord-286950-j7m69833 129 17 small small JJ cord-286950-j7m69833 129 18 part part NN cord-286950-j7m69833 129 19 of of IN cord-286950-j7m69833 129 20 a a DT cord-286950-j7m69833 129 21 more more RBR cord-286950-j7m69833 129 22 comprehensive comprehensive JJ cord-286950-j7m69833 129 23 cost cost NN cord-286950-j7m69833 129 24 - - HYPH cord-286950-j7m69833 129 25 benefit benefit NN cord-286950-j7m69833 129 26 analysis analysis NN cord-286950-j7m69833 129 27 , , , cord-286950-j7m69833 129 28 which which WDT cord-286950-j7m69833 129 29 must must MD cord-286950-j7m69833 129 30 always always RB cord-286950-j7m69833 129 31 compare compare VB cord-286950-j7m69833 129 32 the the DT cord-286950-j7m69833 129 33 costs cost NNS cord-286950-j7m69833 129 34 and and CC cord-286950-j7m69833 129 35 benefits benefit NNS cord-286950-j7m69833 129 36 of of IN cord-286950-j7m69833 129 37 alternative alternative JJ cord-286950-j7m69833 129 38 courses course NNS cord-286950-j7m69833 129 39 of of IN cord-286950-j7m69833 129 40 action action NN cord-286950-j7m69833 129 41 . . . cord-286950-j7m69833 130 1 Proponents proponent NNS cord-286950-j7m69833 130 2 of of IN cord-286950-j7m69833 130 3 GOF GOF NNP cord-286950-j7m69833 130 4 research research NN cord-286950-j7m69833 130 5 argue argue VBP cord-286950-j7m69833 130 6 that that IN cord-286950-j7m69833 130 7 it -PRON- PRP cord-286950-j7m69833 130 8 can can MD cord-286950-j7m69833 130 9 play play VB cord-286950-j7m69833 130 10 a a DT cord-286950-j7m69833 130 11 crucial crucial JJ cord-286950-j7m69833 130 12 role role NN cord-286950-j7m69833 130 13 in in IN cord-286950-j7m69833 130 14 preventing prevent VBG cord-286950-j7m69833 130 15 or or CC cord-286950-j7m69833 130 16 lessening lessen VBG cord-286950-j7m69833 130 17 the the DT cord-286950-j7m69833 130 18 effects effect NNS cord-286950-j7m69833 130 19 of of IN cord-286950-j7m69833 130 20 a a DT cord-286950-j7m69833 130 21 global global JJ cord-286950-j7m69833 130 22 pandemic pandemic NN cord-286950-j7m69833 130 23 by by IN cord-286950-j7m69833 130 24 enabling enable VBG cord-286950-j7m69833 130 25 mitigation mitigation NN cord-286950-j7m69833 130 26 factors factor NNS cord-286950-j7m69833 130 27 such such JJ cord-286950-j7m69833 130 28 as as IN cord-286950-j7m69833 130 29 early early JJ cord-286950-j7m69833 130 30 detection detection NN cord-286950-j7m69833 130 31 and and CC cord-286950-j7m69833 130 32 the the DT cord-286950-j7m69833 130 33 rapid rapid JJ cord-286950-j7m69833 130 34 development development NN cord-286950-j7m69833 130 35 of of IN cord-286950-j7m69833 130 36 vaccines vaccine NNS cord-286950-j7m69833 130 37 . . . cord-286950-j7m69833 131 1 One one CD cord-286950-j7m69833 131 2 obvious obvious JJ cord-286950-j7m69833 131 3 additional additional JJ cord-286950-j7m69833 131 4 risk risk NN cord-286950-j7m69833 131 5 , , , cord-286950-j7m69833 131 6 then then RB cord-286950-j7m69833 131 7 , , , cord-286950-j7m69833 131 8 is be VBZ cord-286950-j7m69833 131 9 the the DT cord-286950-j7m69833 131 10 risk risk NN cord-286950-j7m69833 131 11 of of IN cord-286950-j7m69833 131 12 a a DT cord-286950-j7m69833 131 13 global global JJ cord-286950-j7m69833 131 14 pandemic pandemic NN cord-286950-j7m69833 131 15 that that WDT cord-286950-j7m69833 131 16 might may MD cord-286950-j7m69833 131 17 have have VB cord-286950-j7m69833 131 18 been be VBN cord-286950-j7m69833 131 19 prevented prevent VBN cord-286950-j7m69833 131 20 or or CC cord-286950-j7m69833 131 21 mitigated mitigate VBN cord-286950-j7m69833 131 22 by by IN cord-286950-j7m69833 131 23 continuing continue VBG cord-286950-j7m69833 131 24 GOF GOF NNP cord-286950-j7m69833 131 25 research research NN cord-286950-j7m69833 131 26 . . . cord-286950-j7m69833 132 1 That that DT cord-286950-j7m69833 132 2 risk risk NN cord-286950-j7m69833 132 3 is be VBZ cord-286950-j7m69833 132 4 even even RB cord-286950-j7m69833 132 5 more more RBR cord-286950-j7m69833 132 6 difficult difficult JJ cord-286950-j7m69833 132 7 to to TO cord-286950-j7m69833 132 8 quantify quantify VB cord-286950-j7m69833 132 9 than than IN cord-286950-j7m69833 132 10 the the DT cord-286950-j7m69833 132 11 risk risk NN cord-286950-j7m69833 132 12 of of IN cord-286950-j7m69833 132 13 pandemic pandemic NN cord-286950-j7m69833 132 14 through through IN cord-286950-j7m69833 132 15 accidental accidental JJ cord-286950-j7m69833 132 16 release release NN cord-286950-j7m69833 132 17 . . . cord-286950-j7m69833 133 1 Still still RB cord-286950-j7m69833 133 2 , , , cord-286950-j7m69833 133 3 it -PRON- PRP cord-286950-j7m69833 133 4 must must MD cord-286950-j7m69833 133 5 be be VB cord-286950-j7m69833 133 6 part part NN cord-286950-j7m69833 133 7 of of IN cord-286950-j7m69833 133 8 a a DT cord-286950-j7m69833 133 9 comprehensive comprehensive JJ cord-286950-j7m69833 133 10 analysis analysis NN cord-286950-j7m69833 133 11 , , , cord-286950-j7m69833 133 12 and and CC cord-286950-j7m69833 133 13 since since IN cord-286950-j7m69833 133 14 its -PRON- PRP$ cord-286950-j7m69833 133 15 major major JJ cord-286950-j7m69833 133 16 consequence consequence NN cord-286950-j7m69833 133 17 , , , cord-286950-j7m69833 133 18 e.g. e.g. RB cord-286950-j7m69833 133 19 , , , cord-286950-j7m69833 133 20 a a DT cord-286950-j7m69833 133 21 global global JJ cord-286950-j7m69833 133 22 pandemic pandemic NN cord-286950-j7m69833 133 23 , , , cord-286950-j7m69833 133 24 is be VBZ cord-286950-j7m69833 133 25 just just RB cord-286950-j7m69833 133 26 as as RB cord-286950-j7m69833 133 27 severe severe JJ cord-286950-j7m69833 133 28 as as IN cord-286950-j7m69833 133 29 a a DT cord-286950-j7m69833 133 30 pandemic pandemic NN cord-286950-j7m69833 133 31 caused cause VBN cord-286950-j7m69833 133 32 by by IN cord-286950-j7m69833 133 33 accidental accidental JJ cord-286950-j7m69833 133 34 release release NN cord-286950-j7m69833 133 35 , , , cord-286950-j7m69833 133 36 such such PDT cord-286950-j7m69833 133 37 a a DT cord-286950-j7m69833 133 38 scenario scenario NN cord-286950-j7m69833 133 39 would would MD cord-286950-j7m69833 133 40 loom loom VB cord-286950-j7m69833 133 41 just just RB cord-286950-j7m69833 133 42 as as RB cord-286950-j7m69833 133 43 large large JJ cord-286950-j7m69833 133 44 as as IN cord-286950-j7m69833 133 45 the the DT cord-286950-j7m69833 133 46 accidental accidental JJ cord-286950-j7m69833 133 47 release release NN cord-286950-j7m69833 133 48 scenario scenario NN cord-286950-j7m69833 133 49 in in IN cord-286950-j7m69833 133 50 a a DT cord-286950-j7m69833 133 51 thorough thorough JJ cord-286950-j7m69833 133 52 cost cost NN cord-286950-j7m69833 133 53 - - HYPH cord-286950-j7m69833 133 54 benefit benefit NN cord-286950-j7m69833 133 55 analysis analysis NN cord-286950-j7m69833 133 56 . . . cord-286950-j7m69833 134 1 Another another DT cord-286950-j7m69833 134 2 deep deep JJ cord-286950-j7m69833 134 3 problem problem NN cord-286950-j7m69833 134 4 with with IN cord-286950-j7m69833 134 5 conventional conventional JJ cord-286950-j7m69833 134 6 cost cost NN cord-286950-j7m69833 134 7 - - HYPH cord-286950-j7m69833 134 8 benefit benefit NN cord-286950-j7m69833 134 9 analyses analysis NNS cord-286950-j7m69833 134 10 is be VBZ cord-286950-j7m69833 134 11 that that IN cord-286950-j7m69833 134 12 they -PRON- PRP cord-286950-j7m69833 134 13 usually usually RB cord-286950-j7m69833 134 14 do do VBP cord-286950-j7m69833 134 15 not not RB cord-286950-j7m69833 134 16 include include VB cord-286950-j7m69833 134 17 the the DT cord-286950-j7m69833 134 18 intrinsic intrinsic JJ cord-286950-j7m69833 134 19 benefit benefit NN cord-286950-j7m69833 134 20 of of IN cord-286950-j7m69833 134 21 new new JJ cord-286950-j7m69833 134 22 knowledge knowledge NN cord-286950-j7m69833 134 23 [ [ -LRB- cord-286950-j7m69833 134 24 9 9 CD cord-286950-j7m69833 134 25 ] ] -RRB- cord-286950-j7m69833 134 26 . . . cord-286950-j7m69833 135 1 One one PRP cord-286950-j7m69833 135 2 might may MD cord-286950-j7m69833 135 3 think think VB cord-286950-j7m69833 135 4 that that IN cord-286950-j7m69833 135 5 " " `` cord-286950-j7m69833 135 6 knowledge knowledge NN cord-286950-j7m69833 135 7 " " '' cord-286950-j7m69833 135 8 is be VBZ cord-286950-j7m69833 135 9 something something NN cord-286950-j7m69833 135 10 too too RB cord-286950-j7m69833 135 11 ephemeral ephemeral JJ cord-286950-j7m69833 135 12 to to TO cord-286950-j7m69833 135 13 be be VB cord-286950-j7m69833 135 14 quantified quantify VBN cord-286950-j7m69833 135 15 , , , cord-286950-j7m69833 135 16 or or CC cord-286950-j7m69833 135 17 one one PRP cord-286950-j7m69833 135 18 might may MD cord-286950-j7m69833 135 19 argue argue VB cord-286950-j7m69833 135 20 that that IN cord-286950-j7m69833 135 21 , , , cord-286950-j7m69833 135 22 if if IN cord-286950-j7m69833 135 23 knowledge knowledge NN cord-286950-j7m69833 135 24 counts count VBZ cord-286950-j7m69833 135 25 as as IN cord-286950-j7m69833 135 26 a a DT cord-286950-j7m69833 135 27 " " `` cord-286950-j7m69833 135 28 benefit benefit NN cord-286950-j7m69833 135 29 , , , cord-286950-j7m69833 135 30 " " '' cord-286950-j7m69833 135 31 it -PRON- PRP cord-286950-j7m69833 135 32 does do VBZ cord-286950-j7m69833 135 33 so so RB cord-286950-j7m69833 135 34 only only RB cord-286950-j7m69833 135 35 through through IN cord-286950-j7m69833 135 36 the the DT cord-286950-j7m69833 135 37 consequences consequence NNS cord-286950-j7m69833 135 38 of of IN cord-286950-j7m69833 135 39 such such JJ cord-286950-j7m69833 135 40 knowledge knowledge NN cord-286950-j7m69833 135 41 for for IN cord-286950-j7m69833 135 42 human human JJ cord-286950-j7m69833 135 43 flourishing flourishing NN cord-286950-j7m69833 135 44 , , , cord-286950-j7m69833 135 45 which which WDT cord-286950-j7m69833 135 46 means mean VBZ cord-286950-j7m69833 135 47 that that IN cord-286950-j7m69833 135 48 it -PRON- PRP cord-286950-j7m69833 135 49 does do VBZ cord-286950-j7m69833 135 50 enter enter VB cord-286950-j7m69833 135 51 our -PRON- PRP$ cord-286950-j7m69833 135 52 calculations calculation NNS cord-286950-j7m69833 135 53 indirectly indirectly RB cord-286950-j7m69833 135 54 though though IN cord-286950-j7m69833 135 55 measures measure NNS cord-286950-j7m69833 135 56 of of IN cord-286950-j7m69833 135 57 the the DT cord-286950-j7m69833 135 58 costs cost NNS cord-286950-j7m69833 135 59 and and CC cord-286950-j7m69833 135 60 benefits benefit NNS cord-286950-j7m69833 135 61 of of IN cord-286950-j7m69833 135 62 human human JJ cord-286950-j7m69833 135 63 health health NN cord-286950-j7m69833 135 64 and and CC cord-286950-j7m69833 135 65 human human JJ cord-286950-j7m69833 135 66 suffering suffering NN cord-286950-j7m69833 135 67 . . . cord-286950-j7m69833 136 1 One one NN cord-286950-j7m69833 136 2 does do VBZ cord-286950-j7m69833 136 3 not not RB cord-286950-j7m69833 136 4 want want VB cord-286950-j7m69833 136 5 to to TO cord-286950-j7m69833 136 6 indulge indulge VB cord-286950-j7m69833 136 7 uncritically uncritically RB cord-286950-j7m69833 136 8 in in IN cord-286950-j7m69833 136 9 the the DT cord-286950-j7m69833 136 10 mantra mantra NN cord-286950-j7m69833 136 11 of of IN cord-286950-j7m69833 136 12 knowledge knowledge NN cord-286950-j7m69833 136 13 for for IN cord-286950-j7m69833 136 14 knowledge knowledge NN cord-286950-j7m69833 136 15 's 's POS cord-286950-j7m69833 136 16 own own JJ cord-286950-j7m69833 136 17 sake sake NN cord-286950-j7m69833 136 18 , , , cord-286950-j7m69833 136 19 a a DT cord-286950-j7m69833 136 20 trope trope NN cord-286950-j7m69833 136 21 that that WDT cord-286950-j7m69833 136 22 has have VBZ cord-286950-j7m69833 136 23 too too RB cord-286950-j7m69833 136 24 often often RB cord-286950-j7m69833 136 25 been be VBN cord-286950-j7m69833 136 26 used use VBN cord-286950-j7m69833 136 27 to to TO cord-286950-j7m69833 136 28 justify justify VB cord-286950-j7m69833 136 29 research research NN cord-286950-j7m69833 136 30 , , , cord-286950-j7m69833 136 31 but but CC cord-286950-j7m69833 136 32 the the DT cord-286950-j7m69833 136 33 fact fact NN cord-286950-j7m69833 136 34 remains remain VBZ cord-286950-j7m69833 136 35 that that IN cord-286950-j7m69833 136 36 , , , cord-286950-j7m69833 136 37 on on IN cord-286950-j7m69833 136 38 the the DT cord-286950-j7m69833 136 39 whole whole NN cord-286950-j7m69833 136 40 , , , cord-286950-j7m69833 136 41 increased increase VBN cord-286950-j7m69833 136 42 knowledge knowledge NN cord-286950-j7m69833 136 43 brings bring VBZ cord-286950-j7m69833 136 44 increased increase VBN cord-286950-j7m69833 136 45 ability ability NN cord-286950-j7m69833 136 46 to to TO cord-286950-j7m69833 136 47 promote promote VB cord-286950-j7m69833 136 48 the the DT cord-286950-j7m69833 136 49 good good NN cord-286950-j7m69833 136 50 and and CC cord-286950-j7m69833 136 51 to to TO cord-286950-j7m69833 136 52 mitigate mitigate VB cord-286950-j7m69833 136 53 suffering suffering NN cord-286950-j7m69833 136 54 . . . cord-286950-j7m69833 137 1 New new JJ cord-286950-j7m69833 137 2 knowledge knowledge NN cord-286950-j7m69833 137 3 can can MD cord-286950-j7m69833 137 4 always always RB cord-286950-j7m69833 137 5 be be VB cord-286950-j7m69833 137 6 used use VBN cord-286950-j7m69833 137 7 for for IN cord-286950-j7m69833 137 8 evil evil JJ cord-286950-j7m69833 137 9 ends end NNS cord-286950-j7m69833 137 10 , , , cord-286950-j7m69833 137 11 but but CC cord-286950-j7m69833 137 12 how how WRB cord-286950-j7m69833 137 13 we -PRON- PRP cord-286950-j7m69833 137 14 use use VBP cord-286950-j7m69833 137 15 that that DT cord-286950-j7m69833 137 16 knowledge knowledge NN cord-286950-j7m69833 137 17 is be VBZ cord-286950-j7m69833 137 18 a a DT cord-286950-j7m69833 137 19 moral moral JJ cord-286950-j7m69833 137 20 choice choice NN cord-286950-j7m69833 137 21 , , , cord-286950-j7m69833 137 22 and and CC cord-286950-j7m69833 137 23 if if IN cord-286950-j7m69833 137 24 we -PRON- PRP cord-286950-j7m69833 137 25 do do VBP cord-286950-j7m69833 137 26 n't not RB cord-286950-j7m69833 137 27 have have VB cord-286950-j7m69833 137 28 that that DT cord-286950-j7m69833 137 29 knowledge knowledge NN cord-286950-j7m69833 137 30 in in IN cord-286950-j7m69833 137 31 the the DT cord-286950-j7m69833 137 32 first first JJ cord-286950-j7m69833 137 33 place place NN cord-286950-j7m69833 137 34 , , , cord-286950-j7m69833 137 35 then then RB cord-286950-j7m69833 137 36 we -PRON- PRP cord-286950-j7m69833 137 37 can can MD cord-286950-j7m69833 137 38 not not RB cord-286950-j7m69833 137 39 use use VB cord-286950-j7m69833 137 40 it -PRON- PRP cord-286950-j7m69833 137 41 for for IN cord-286950-j7m69833 137 42 the the DT cord-286950-j7m69833 137 43 good good NN cord-286950-j7m69833 137 44 . . . cord-286950-j7m69833 138 1 Exactly exactly RB cord-286950-j7m69833 138 2 how how WRB cord-286950-j7m69833 138 3 new new JJ cord-286950-j7m69833 138 4 knowledge knowledge NN cord-286950-j7m69833 138 5 will will MD cord-286950-j7m69833 138 6 contribute contribute VB cord-286950-j7m69833 138 7 to to IN cord-286950-j7m69833 138 8 future future JJ cord-286950-j7m69833 138 9 human human JJ cord-286950-j7m69833 138 10 flourishing flourishing NN cord-286950-j7m69833 138 11 in in IN cord-286950-j7m69833 138 12 a a DT cord-286950-j7m69833 138 13 complex complex JJ cord-286950-j7m69833 138 14 and and CC cord-286950-j7m69833 138 15 rapidly rapidly RB cord-286950-j7m69833 138 16 changing change VBG cord-286950-j7m69833 138 17 technical technical JJ cord-286950-j7m69833 138 18 and and CC cord-286950-j7m69833 138 19 social social JJ cord-286950-j7m69833 138 20 world world NN cord-286950-j7m69833 138 21 is be VBZ cord-286950-j7m69833 138 22 usually usually RB cord-286950-j7m69833 138 23 unforeseeable unforeseeable JJ cord-286950-j7m69833 138 24 at at IN cord-286950-j7m69833 138 25 the the DT cord-286950-j7m69833 138 26 time time NN cord-286950-j7m69833 138 27 when when WRB cord-286950-j7m69833 138 28 the the DT cord-286950-j7m69833 138 29 new new JJ cord-286950-j7m69833 138 30 knowledge knowledge NN cord-286950-j7m69833 138 31 is be VBZ cord-286950-j7m69833 138 32 first first RB cord-286950-j7m69833 138 33 generated generate VBN cord-286950-j7m69833 138 34 . . . cord-286950-j7m69833 139 1 Technology technology NN cord-286950-j7m69833 139 2 ethicist ethicist NN cord-286950-j7m69833 139 3 Shannon Shannon NNP cord-286950-j7m69833 139 4 Vallor Vallor NNP cord-286950-j7m69833 139 5 dubs dub VBZ cord-286950-j7m69833 139 6 this this DT cord-286950-j7m69833 139 7 the the DT cord-286950-j7m69833 139 8 problem problem NN cord-286950-j7m69833 139 9 of of IN cord-286950-j7m69833 139 10 " " `` cord-286950-j7m69833 139 11 technosocial technosocial JJ cord-286950-j7m69833 139 12 opacity opacity NN cord-286950-j7m69833 139 13 " " '' cord-286950-j7m69833 139 14 [ [ -LRB- cord-286950-j7m69833 139 15 39 39 CD cord-286950-j7m69833 139 16 ] ] -RRB- cord-286950-j7m69833 139 17 . . . cord-286950-j7m69833 140 1 Thus thus RB cord-286950-j7m69833 140 2 , , , cord-286950-j7m69833 140 3 it -PRON- PRP cord-286950-j7m69833 140 4 would would MD cord-286950-j7m69833 140 5 seem seem VB cord-286950-j7m69833 140 6 impossible impossible JJ cord-286950-j7m69833 140 7 to to TO cord-286950-j7m69833 140 8 include include VB cord-286950-j7m69833 140 9 the the DT cord-286950-j7m69833 140 10 long long JJ cord-286950-j7m69833 140 11 - - HYPH cord-286950-j7m69833 140 12 term term NN cord-286950-j7m69833 140 13 effects effect NNS cord-286950-j7m69833 140 14 of of IN cord-286950-j7m69833 140 15 new new JJ cord-286950-j7m69833 140 16 knowledge knowledge NN cord-286950-j7m69833 140 17 production production NN cord-286950-j7m69833 140 18 in in IN cord-286950-j7m69833 140 19 a a DT cord-286950-j7m69833 140 20 cost cost NN cord-286950-j7m69833 140 21 - - HYPH cord-286950-j7m69833 140 22 benefit benefit NN cord-286950-j7m69833 140 23 analysis analysis NN cord-286950-j7m69833 140 24 of of IN cord-286950-j7m69833 140 25 the the DT cord-286950-j7m69833 140 26 research research NN cord-286950-j7m69833 140 27 generating generate VBG cord-286950-j7m69833 140 28 that that DT cord-286950-j7m69833 140 29 knowledge knowledge NN cord-286950-j7m69833 140 30 . . . cord-286950-j7m69833 141 1 The the DT cord-286950-j7m69833 141 2 only only JJ cord-286950-j7m69833 141 3 way way NN cord-286950-j7m69833 141 4 to to TO cord-286950-j7m69833 141 5 fairly fairly RB cord-286950-j7m69833 141 6 assess assess VB cord-286950-j7m69833 141 7 the the DT cord-286950-j7m69833 141 8 benefits benefit NNS cord-286950-j7m69833 141 9 of of IN cord-286950-j7m69833 141 10 such such JJ cord-286950-j7m69833 141 11 research research NN cord-286950-j7m69833 141 12 is be VBZ cord-286950-j7m69833 141 13 to to TO cord-286950-j7m69833 141 14 put put VB cord-286950-j7m69833 141 15 a a DT cord-286950-j7m69833 141 16 premium premium NN cord-286950-j7m69833 141 17 on on IN cord-286950-j7m69833 141 18 knowledge knowledge NN cord-286950-j7m69833 141 19 production production NN cord-286950-j7m69833 141 20 per per FW cord-286950-j7m69833 141 21 se se FW cord-286950-j7m69833 141 22 . . . cord-286950-j7m69833 142 1 How how WRB cord-286950-j7m69833 142 2 to to TO cord-286950-j7m69833 142 3 do do VB cord-286950-j7m69833 142 4 that that DT cord-286950-j7m69833 142 5 is be VBZ cord-286950-j7m69833 142 6 the the DT cord-286950-j7m69833 142 7 hard hard JJ cord-286950-j7m69833 142 8 problem problem NN cord-286950-j7m69833 142 9 , , , cord-286950-j7m69833 142 10 and and CC cord-286950-j7m69833 142 11 that that IN cord-286950-j7m69833 142 12 difficulty difficulty NN cord-286950-j7m69833 142 13 must must MD cord-286950-j7m69833 142 14 be be VB cord-286950-j7m69833 142 15 added add VBN cord-286950-j7m69833 142 16 to to IN cord-286950-j7m69833 142 17 the the DT cord-286950-j7m69833 142 18 list list NN cord-286950-j7m69833 142 19 of of IN cord-286950-j7m69833 142 20 reasons reason NNS cord-286950-j7m69833 142 21 suggesting suggest VBG cord-286950-j7m69833 142 22 that that IN cord-286950-j7m69833 142 23 cost cost NN cord-286950-j7m69833 142 24 - - HYPH cord-286950-j7m69833 142 25 benefit benefit NN cord-286950-j7m69833 142 26 analysis analysis NN cord-286950-j7m69833 142 27 is be VBZ cord-286950-j7m69833 142 28 a a DT cord-286950-j7m69833 142 29 seriously seriously RB cord-286950-j7m69833 142 30 limited limited JJ cord-286950-j7m69833 142 31 tool tool NN cord-286950-j7m69833 142 32 for for IN cord-286950-j7m69833 142 33 policymaking policymake VBG cord-286950-j7m69833 142 34 about about IN cord-286950-j7m69833 142 35 scientific scientific JJ cord-286950-j7m69833 142 36 research research NN cord-286950-j7m69833 142 37 . . . cord-286950-j7m69833 143 1 Perhaps perhaps RB cord-286950-j7m69833 143 2 the the DT cord-286950-j7m69833 143 3 deepest deep JJS cord-286950-j7m69833 143 4 problem problem NN cord-286950-j7m69833 143 5 with with IN cord-286950-j7m69833 143 6 the the DT cord-286950-j7m69833 143 7 cost cost NN cord-286950-j7m69833 143 8 - - HYPH cord-286950-j7m69833 143 9 benefit benefit NN cord-286950-j7m69833 143 10 approach approach NN cord-286950-j7m69833 143 11 to to IN cord-286950-j7m69833 143 12 policymaking policymaking NN cord-286950-j7m69833 143 13 is be VBZ cord-286950-j7m69833 143 14 what what WP cord-286950-j7m69833 143 15 we -PRON- PRP cord-286950-j7m69833 143 16 have have VBP cord-286950-j7m69833 143 17 termed term VBN cord-286950-j7m69833 143 18 elsewhere elsewhere RB cord-286950-j7m69833 143 19 the the DT cord-286950-j7m69833 143 20 " " `` cord-286950-j7m69833 143 21 apocalyptic apocalyptic JJ cord-286950-j7m69833 143 22 fallacy fallacy NN cord-286950-j7m69833 143 23 " " '' cord-286950-j7m69833 143 24 [ [ -LRB- cord-286950-j7m69833 143 25 40 40 CD cord-286950-j7m69833 143 26 ] ] -RRB- cord-286950-j7m69833 143 27 . . . cord-286950-j7m69833 144 1 Imagining imagine VBG cord-286950-j7m69833 144 2 an an DT cord-286950-j7m69833 144 3 unintentional unintentional JJ cord-286950-j7m69833 144 4 , , , cord-286950-j7m69833 144 5 global global JJ cord-286950-j7m69833 144 6 pandemic pandemic NN cord-286950-j7m69833 144 7 as as IN cord-286950-j7m69833 144 8 one one CD cord-286950-j7m69833 144 9 possible possible JJ cord-286950-j7m69833 144 10 outcome outcome NN cord-286950-j7m69833 144 11 of of IN cord-286950-j7m69833 144 12 GOF GOF NNP cord-286950-j7m69833 144 13 research research NN cord-286950-j7m69833 144 14 is be VBZ cord-286950-j7m69833 144 15 tantamount tantamount JJ cord-286950-j7m69833 144 16 to to IN cord-286950-j7m69833 144 17 assigning assign VBG cord-286950-j7m69833 144 18 infinite infinite JJ cord-286950-j7m69833 144 19 negative negative JJ cord-286950-j7m69833 144 20 utility utility NN cord-286950-j7m69833 144 21 to to IN cord-286950-j7m69833 144 22 such such JJ cord-286950-j7m69833 144 23 research research NN cord-286950-j7m69833 144 24 in in IN cord-286950-j7m69833 144 25 a a DT cord-286950-j7m69833 144 26 cost cost NN cord-286950-j7m69833 144 27 - - HYPH cord-286950-j7m69833 144 28 benefit benefit NN cord-286950-j7m69833 144 29 analysis analysis NN cord-286950-j7m69833 144 30 . . . cord-286950-j7m69833 145 1 Thus thus RB cord-286950-j7m69833 145 2 , , , cord-286950-j7m69833 145 3 it -PRON- PRP cord-286950-j7m69833 145 4 makes make VBZ cord-286950-j7m69833 145 5 no no DT cord-286950-j7m69833 145 6 difference difference NN cord-286950-j7m69833 145 7 how how WRB cord-286950-j7m69833 145 8 low low JJ cord-286950-j7m69833 145 9 the the DT cord-286950-j7m69833 145 10 probability probability NN cord-286950-j7m69833 145 11 of of IN cord-286950-j7m69833 145 12 such such PDT cord-286950-j7m69833 145 13 an an DT cord-286950-j7m69833 145 14 outcome outcome NN cord-286950-j7m69833 145 15 might may MD cord-286950-j7m69833 145 16 be be VB cord-286950-j7m69833 145 17 . . . cord-286950-j7m69833 146 1 Infinite infinite JJ cord-286950-j7m69833 146 2 negative negative JJ cord-286950-j7m69833 146 3 utility utility NN cord-286950-j7m69833 146 4 , , , cord-286950-j7m69833 146 5 multiplied multiply VBN cord-286950-j7m69833 146 6 by by IN cord-286950-j7m69833 146 7 any any DT cord-286950-j7m69833 146 8 finite finite JJ cord-286950-j7m69833 146 9 probability probability NN cord-286950-j7m69833 146 10 , , , cord-286950-j7m69833 146 11 totally totally RB cord-286950-j7m69833 146 12 swamps swamp VBZ cord-286950-j7m69833 146 13 every every DT cord-286950-j7m69833 146 14 other other JJ cord-286950-j7m69833 146 15 term term NN cord-286950-j7m69833 146 16 in in IN cord-286950-j7m69833 146 17 a a DT cord-286950-j7m69833 146 18 cost cost NN cord-286950-j7m69833 146 19 - - HYPH cord-286950-j7m69833 146 20 benefit benefit NN cord-286950-j7m69833 146 21 analysis analysis NN cord-286950-j7m69833 146 22 , , , cord-286950-j7m69833 146 23 meaning mean VBG cord-286950-j7m69833 146 24 that that IN cord-286950-j7m69833 146 25 no no DT cord-286950-j7m69833 146 26 imagined imagine VBN cord-286950-j7m69833 146 27 benefits benefit NNS cord-286950-j7m69833 146 28 of of IN cord-286950-j7m69833 146 29 alternative alternative JJ cord-286950-j7m69833 146 30 courses course NNS cord-286950-j7m69833 146 31 of of IN cord-286950-j7m69833 146 32 action action NN cord-286950-j7m69833 146 33 , , , cord-286950-j7m69833 146 34 however however RB cord-286950-j7m69833 146 35 great great JJ cord-286950-j7m69833 146 36 ( ( -LRB- cord-286950-j7m69833 146 37 excepting except VBG cord-286950-j7m69833 146 38 eternal eternal JJ cord-286950-j7m69833 146 39 salvation salvation NN cord-286950-j7m69833 146 40 for for IN cord-286950-j7m69833 146 41 all all DT cord-286950-j7m69833 146 42 of of IN cord-286950-j7m69833 146 43 humankind humankind NN cord-286950-j7m69833 146 44 ) ) -RRB- cord-286950-j7m69833 146 45 , , , cord-286950-j7m69833 146 46 can can MD cord-286950-j7m69833 146 47 make make VB cord-286950-j7m69833 146 48 a a DT cord-286950-j7m69833 146 49 difference difference NN cord-286950-j7m69833 146 50 in in IN cord-286950-j7m69833 146 51 the the DT cord-286950-j7m69833 146 52 calculation calculation NN cord-286950-j7m69833 146 53 . . . cord-286950-j7m69833 147 1 What what WP cord-286950-j7m69833 147 2 this this DT cord-286950-j7m69833 147 3 means mean VBZ cord-286950-j7m69833 147 4 is be VBZ cord-286950-j7m69833 147 5 that that DT cord-286950-j7m69833 147 6 cost cost NN cord-286950-j7m69833 147 7 - - HYPH cord-286950-j7m69833 147 8 benefit benefit NN cord-286950-j7m69833 147 9 analysis analysis NN cord-286950-j7m69833 147 10 is be VBZ cord-286950-j7m69833 147 11 , , , cord-286950-j7m69833 147 12 effectively effectively RB cord-286950-j7m69833 147 13 , , , cord-286950-j7m69833 147 14 useless useless JJ cord-286950-j7m69833 147 15 in in IN cord-286950-j7m69833 147 16 such such JJ cord-286950-j7m69833 147 17 settings setting NNS cord-286950-j7m69833 147 18 , , , cord-286950-j7m69833 147 19 at at IN cord-286950-j7m69833 147 20 least least JJS cord-286950-j7m69833 147 21 with with IN cord-286950-j7m69833 147 22 regard regard NN cord-286950-j7m69833 147 23 to to IN cord-286950-j7m69833 147 24 the the DT cord-286950-j7m69833 147 25 moral moral JJ cord-286950-j7m69833 147 26 assessment assessment NN cord-286950-j7m69833 147 27 of of IN cord-286950-j7m69833 147 28 something something NN cord-286950-j7m69833 147 29 like like IN cord-286950-j7m69833 147 30 GOF GOF NNP cord-286950-j7m69833 147 31 research research NN cord-286950-j7m69833 147 32 . . . cord-286950-j7m69833 148 1 If if IN cord-286950-j7m69833 148 2 cost cost NN cord-286950-j7m69833 148 3 - - HYPH cord-286950-j7m69833 148 4 benefit benefit NN cord-286950-j7m69833 148 5 analysis analysis NN cord-286950-j7m69833 148 6 is be VBZ cord-286950-j7m69833 148 7 the the DT cord-286950-j7m69833 148 8 epitome epitome NN cord-286950-j7m69833 148 9 of of IN cord-286950-j7m69833 148 10 reason reason NN cord-286950-j7m69833 148 11 and and CC cord-286950-j7m69833 148 12 rationality rationality NN cord-286950-j7m69833 148 13 in in IN cord-286950-j7m69833 148 14 policymaking policymaking NN cord-286950-j7m69833 148 15 , , , cord-286950-j7m69833 148 16 then then RB cord-286950-j7m69833 148 17 reason reason NN cord-286950-j7m69833 148 18 fails fail VBZ cord-286950-j7m69833 148 19 us -PRON- PRP cord-286950-j7m69833 148 20 in in IN cord-286950-j7m69833 148 21 cases case NNS cord-286950-j7m69833 148 22 where where WRB cord-286950-j7m69833 148 23 the the DT cord-286950-j7m69833 148 24 risks risk NNS cord-286950-j7m69833 148 25 include include VBP cord-286950-j7m69833 148 26 the the DT cord-286950-j7m69833 148 27 extermination extermination NN cord-286950-j7m69833 148 28 of of IN cord-286950-j7m69833 148 29 a a DT cord-286950-j7m69833 148 30 significant significant JJ cord-286950-j7m69833 148 31 fraction fraction NN cord-286950-j7m69833 148 32 of of IN cord-286950-j7m69833 148 33 all all DT cord-286950-j7m69833 148 34 human human JJ cord-286950-j7m69833 148 35 life life NN cord-286950-j7m69833 148 36 . . . cord-286950-j7m69833 149 1 Nevertheless nevertheless RB cord-286950-j7m69833 149 2 , , , cord-286950-j7m69833 149 3 there there EX cord-286950-j7m69833 149 4 is be VBZ cord-286950-j7m69833 149 5 still still RB cord-286950-j7m69833 149 6 value value NN cord-286950-j7m69833 149 7 in in IN cord-286950-j7m69833 149 8 risk risk NN cord-286950-j7m69833 149 9 analysis analysis NN cord-286950-j7m69833 149 10 . . . cord-286950-j7m69833 150 1 As as IN cord-286950-j7m69833 150 2 the the DT cord-286950-j7m69833 150 3 abovecited abovecited NNP cord-286950-j7m69833 150 4 simulation simulation NN cord-286950-j7m69833 150 5 study study NN cord-286950-j7m69833 150 6 of of IN cord-286950-j7m69833 150 7 disease disease NN cord-286950-j7m69833 150 8 spread spread VBN cord-286950-j7m69833 150 9 after after IN cord-286950-j7m69833 150 10 accidental accidental JJ cord-286950-j7m69833 150 11 exposure exposure NN cord-286950-j7m69833 150 12 and and CC cord-286950-j7m69833 150 13 release release NN cord-286950-j7m69833 150 14 amply amply RB cord-286950-j7m69833 150 15 demonstrates demonstrate VBZ cord-286950-j7m69833 150 16 , , , cord-286950-j7m69833 150 17 a a DT cord-286950-j7m69833 150 18 careful careful JJ cord-286950-j7m69833 150 19 risk risk NN cord-286950-j7m69833 150 20 analysis analysis NN cord-286950-j7m69833 150 21 can can MD cord-286950-j7m69833 150 22 point point VB cord-286950-j7m69833 150 23 us -PRON- PRP cord-286950-j7m69833 150 24 toward toward IN cord-286950-j7m69833 150 25 those those DT cord-286950-j7m69833 150 26 factors factor NNS cord-286950-j7m69833 150 27 that that WDT cord-286950-j7m69833 150 28 are be VBP cord-286950-j7m69833 150 29 critical critical JJ cord-286950-j7m69833 150 30 for for IN cord-286950-j7m69833 150 31 minimizing minimize VBG cord-286950-j7m69833 150 32 risk risk NN cord-286950-j7m69833 150 33 , , , cord-286950-j7m69833 150 34 such such JJ cord-286950-j7m69833 150 35 as as IN cord-286950-j7m69833 150 36 enhanced enhance VBN cord-286950-j7m69833 150 37 biosafety biosafety NN cord-286950-j7m69833 150 38 protocols protocol NNS cord-286950-j7m69833 150 39 and and CC cord-286950-j7m69833 150 40 rapid rapid JJ cord-286950-j7m69833 150 41 public public JJ cord-286950-j7m69833 150 42 health health NN cord-286950-j7m69833 150 43 responses response NNS cord-286950-j7m69833 150 44 . . . cord-286950-j7m69833 151 1 But but CC cord-286950-j7m69833 151 2 when when WRB cord-286950-j7m69833 151 3 promoted promote VBN cord-286950-j7m69833 151 4 to to IN cord-286950-j7m69833 151 5 the the DT cord-286950-j7m69833 151 6 public public NN cord-286950-j7m69833 151 7 and and CC cord-286950-j7m69833 151 8 policymakers policymaker NNS cord-286950-j7m69833 151 9 as as IN cord-286950-j7m69833 151 10 forecasting forecast VBG cord-286950-j7m69833 151 11 a a DT cord-286950-j7m69833 151 12 doomsday doomsday NN cord-286950-j7m69833 151 13 scenario scenario NN cord-286950-j7m69833 151 14 , , , cord-286950-j7m69833 151 15 such such JJ cord-286950-j7m69833 151 16 analyses analysis NNS cord-286950-j7m69833 151 17 risk risk VBP cord-286950-j7m69833 151 18 inducing induce VBG cord-286950-j7m69833 151 19 panic panic NN cord-286950-j7m69833 151 20 that that WDT cord-286950-j7m69833 151 21 overwhelms overwhelm VBZ cord-286950-j7m69833 151 22 practical practical JJ cord-286950-j7m69833 151 23 reason reason NN cord-286950-j7m69833 151 24 . . . cord-286950-j7m69833 152 1 Similarly similarly RB cord-286950-j7m69833 152 2 , , , cord-286950-j7m69833 152 3 comparisons comparison NNS cord-286950-j7m69833 152 4 of of IN cord-286950-j7m69833 152 5 the the DT cord-286950-j7m69833 152 6 risks risk NNS cord-286950-j7m69833 152 7 of of IN cord-286950-j7m69833 152 8 GOF GOF NNP cord-286950-j7m69833 152 9 research research NN cord-286950-j7m69833 152 10 to to IN cord-286950-j7m69833 152 11 the the DT cord-286950-j7m69833 152 12 events event NNS cord-286950-j7m69833 152 13 leading lead VBG cord-286950-j7m69833 152 14 to to IN cord-286950-j7m69833 152 15 the the DT cord-286950-j7m69833 152 16 development development NN cord-286950-j7m69833 152 17 of of IN cord-286950-j7m69833 152 18 the the DT cord-286950-j7m69833 152 19 Nuremberg Nuremberg NNP cord-286950-j7m69833 152 20 Code Code NNP cord-286950-j7m69833 152 21 do do VBP cord-286950-j7m69833 152 22 not not RB cord-286950-j7m69833 152 23 serve serve VB cord-286950-j7m69833 152 24 a a DT cord-286950-j7m69833 152 25 useful useful JJ cord-286950-j7m69833 152 26 purpose purpose NN cord-286950-j7m69833 152 27 in in IN cord-286950-j7m69833 152 28 the the DT cord-286950-j7m69833 152 29 discussion discussion NN cord-286950-j7m69833 152 30 [ [ -LRB- cord-286950-j7m69833 152 31 34 34 CD cord-286950-j7m69833 152 32 ] ] -RRB- cord-286950-j7m69833 152 33 . . . cord-286950-j7m69833 153 1 The the DT cord-286950-j7m69833 153 2 use use NN cord-286950-j7m69833 153 3 of of IN cord-286950-j7m69833 153 4 the the DT cord-286950-j7m69833 153 5 word word NN cord-286950-j7m69833 153 6 " " `` cord-286950-j7m69833 153 7 Nuremberg Nuremberg NNP cord-286950-j7m69833 153 8 " " '' cord-286950-j7m69833 153 9 connotes connote VBZ cord-286950-j7m69833 153 10 an an DT cord-286950-j7m69833 153 11 association association NN cord-286950-j7m69833 153 12 with with IN cord-286950-j7m69833 153 13 war war NN cord-286950-j7m69833 153 14 crimes crime NNS cord-286950-j7m69833 153 15 that that WDT cord-286950-j7m69833 153 16 is be VBZ cord-286950-j7m69833 153 17 simply simply RB cord-286950-j7m69833 153 18 inappropriate inappropriate JJ cord-286950-j7m69833 153 19 for for IN cord-286950-j7m69833 153 20 use use NN cord-286950-j7m69833 153 21 in in IN cord-286950-j7m69833 153 22 a a DT cord-286950-j7m69833 153 23 rational rational JJ cord-286950-j7m69833 153 24 discussion discussion NN cord-286950-j7m69833 153 25 about about IN cord-286950-j7m69833 153 26 experiments experiment NNS cord-286950-j7m69833 153 27 that that WDT cord-286950-j7m69833 153 28 are be VBP cord-286950-j7m69833 153 29 ostensibly ostensibly RB cord-286950-j7m69833 153 30 being be VBG cord-286950-j7m69833 153 31 done do VBN cord-286950-j7m69833 153 32 by by IN cord-286950-j7m69833 153 33 well well RB cord-286950-j7m69833 153 34 - - HYPH cord-286950-j7m69833 153 35 meaning mean VBG cord-286950-j7m69833 153 36 scientists scientist NNS cord-286950-j7m69833 153 37 trying try VBG cord-286950-j7m69833 153 38 to to TO cord-286950-j7m69833 153 39 prepare prepare VB cord-286950-j7m69833 153 40 humanity humanity NN cord-286950-j7m69833 153 41 for for IN cord-286950-j7m69833 153 42 confronting confront VBG cord-286950-j7m69833 153 43 a a DT cord-286950-j7m69833 153 44 potential potential JJ cord-286950-j7m69833 153 45 pandemic pandemic NN cord-286950-j7m69833 153 46 . . . cord-286950-j7m69833 154 1 Although although IN cord-286950-j7m69833 154 2 we -PRON- PRP cord-286950-j7m69833 154 3 are be VBP cord-286950-j7m69833 154 4 well well RB cord-286950-j7m69833 154 5 aware aware JJ cord-286950-j7m69833 154 6 that that IN cord-286950-j7m69833 154 7 the the DT cord-286950-j7m69833 154 8 Nuremberg Nuremberg NNP cord-286950-j7m69833 154 9 Code Code NNP cord-286950-j7m69833 154 10 and and CC cord-286950-j7m69833 154 11 the the DT cord-286950-j7m69833 154 12 war war NN cord-286950-j7m69833 154 13 crimes crime NNS cord-286950-j7m69833 154 14 of of IN cord-286950-j7m69833 154 15 the the DT cord-286950-j7m69833 154 16 high high JJ cord-286950-j7m69833 154 17 echelons echelon NNS cord-286950-j7m69833 154 18 of of IN cord-286950-j7m69833 154 19 the the DT cord-286950-j7m69833 154 20 Nazi Nazi NNP cord-286950-j7m69833 154 21 hierarchy hierarchy NN cord-286950-j7m69833 154 22 are be VBP cord-286950-j7m69833 154 23 very very RB cord-286950-j7m69833 154 24 different different JJ cord-286950-j7m69833 154 25 things thing NNS cord-286950-j7m69833 154 26 , , , cord-286950-j7m69833 154 27 the the DT cord-286950-j7m69833 154 28 problem problem NN cord-286950-j7m69833 154 29 lies lie VBZ cord-286950-j7m69833 154 30 in in IN cord-286950-j7m69833 154 31 the the DT cord-286950-j7m69833 154 32 symbolism symbolism NN cord-286950-j7m69833 154 33 of of IN cord-286950-j7m69833 154 34 the the DT cord-286950-j7m69833 154 35 phrase phrase NN cord-286950-j7m69833 154 36 and and CC cord-286950-j7m69833 154 37 how how WRB cord-286950-j7m69833 154 38 it -PRON- PRP cord-286950-j7m69833 154 39 may may MD cord-286950-j7m69833 154 40 be be VB cord-286950-j7m69833 154 41 perceived perceive VBN cord-286950-j7m69833 154 42 by by IN cord-286950-j7m69833 154 43 the the DT cord-286950-j7m69833 154 44 public public NN cord-286950-j7m69833 154 45 . . . cord-286950-j7m69833 155 1 We -PRON- PRP cord-286950-j7m69833 155 2 urge urge VBP cord-286950-j7m69833 155 3 that that IN cord-286950-j7m69833 155 4 it -PRON- PRP cord-286950-j7m69833 155 5 not not RB cord-286950-j7m69833 155 6 be be VB cord-286950-j7m69833 155 7 used use VBN cord-286950-j7m69833 155 8 and and CC cord-286950-j7m69833 155 9 in in IN cord-286950-j7m69833 155 10 fact fact NN cord-286950-j7m69833 155 11 , , , cord-286950-j7m69833 155 12 it -PRON- PRP cord-286950-j7m69833 155 13 is be VBZ cord-286950-j7m69833 155 14 possible possible JJ cord-286950-j7m69833 155 15 to to TO cord-286950-j7m69833 155 16 discuss discuss VB cord-286950-j7m69833 155 17 these these DT cord-286950-j7m69833 155 18 important important JJ cord-286950-j7m69833 155 19 principles principle NNS cord-286950-j7m69833 155 20 without without IN cord-286950-j7m69833 155 21 invoking invoke VBG cord-286950-j7m69833 155 22 the the DT cord-286950-j7m69833 155 23 name name NN cord-286950-j7m69833 155 24 of of IN cord-286950-j7m69833 155 25 the the DT cord-286950-j7m69833 155 26 city city NN cord-286950-j7m69833 155 27 with with IN cord-286950-j7m69833 155 28 its -PRON- PRP$ cord-286950-j7m69833 155 29 historical historical JJ cord-286950-j7m69833 155 30 baggage baggage NN cord-286950-j7m69833 155 31 . . . cord-286950-j7m69833 156 1 If if IN cord-286950-j7m69833 156 2 cost cost NN cord-286950-j7m69833 156 3 - - HYPH cord-286950-j7m69833 156 4 benefit benefit NN cord-286950-j7m69833 156 5 analysis analysis NN cord-286950-j7m69833 156 6 is be VBZ cord-286950-j7m69833 156 7 not not RB cord-286950-j7m69833 156 8 the the DT cord-286950-j7m69833 156 9 optimal optimal JJ cord-286950-j7m69833 156 10 tool tool NN cord-286950-j7m69833 156 11 for for IN cord-286950-j7m69833 156 12 policymaking policymake VBG cord-286950-j7m69833 156 13 with with IN cord-286950-j7m69833 156 14 respect respect NN cord-286950-j7m69833 156 15 to to IN cord-286950-j7m69833 156 16 GOF GOF NNP cord-286950-j7m69833 156 17 research research NN cord-286950-j7m69833 156 18 , , , cord-286950-j7m69833 156 19 what what WP cord-286950-j7m69833 156 20 is be VBZ cord-286950-j7m69833 156 21 ? ? . cord-286950-j7m69833 157 1 Earlier early RBR cord-286950-j7m69833 157 2 , , , cord-286950-j7m69833 157 3 we -PRON- PRP cord-286950-j7m69833 157 4 mentioned mention VBD cord-286950-j7m69833 157 5 the the DT cord-286950-j7m69833 157 6 virtue virtue NN cord-286950-j7m69833 157 7 of of IN cord-286950-j7m69833 157 8 simple simple JJ cord-286950-j7m69833 157 9 prudence prudence NN cord-286950-j7m69833 157 10 in in IN cord-286950-j7m69833 157 11 thinking think VBG cord-286950-j7m69833 157 12 about about IN cord-286950-j7m69833 157 13 dual dual JJ cord-286950-j7m69833 157 14 - - HYPH cord-286950-j7m69833 157 15 use use NN cord-286950-j7m69833 157 16 research research NN cord-286950-j7m69833 157 17 and and CC cord-286950-j7m69833 157 18 technology technology NN cord-286950-j7m69833 157 19 . . . cord-286950-j7m69833 158 1 Perhaps perhaps RB cord-286950-j7m69833 158 2 that that DT cord-286950-j7m69833 158 3 is be VBZ cord-286950-j7m69833 158 4 the the DT cord-286950-j7m69833 158 5 answer answer NN cord-286950-j7m69833 158 6 here here RB cord-286950-j7m69833 158 7 as as RB cord-286950-j7m69833 158 8 well well RB cord-286950-j7m69833 158 9 . . . cord-286950-j7m69833 159 1 Technology technology NN cord-286950-j7m69833 159 2 ethicists ethicist NNS cord-286950-j7m69833 159 3 have have VBP cord-286950-j7m69833 159 4 given give VBN cord-286950-j7m69833 159 5 the the DT cord-286950-j7m69833 159 6 name name NN cord-286950-j7m69833 159 7 " " `` cord-286950-j7m69833 159 8 precautionary precautionary JJ cord-286950-j7m69833 159 9 principle"-policymakers principle"-policymaker NNS cord-286950-j7m69833 159 10 prefer prefer VBP cord-286950-j7m69833 159 11 sophisticated sophisticated JJ cord-286950-j7m69833 159 12 names name NNS cord-286950-j7m69833 159 13 like like IN cord-286950-j7m69833 159 14 this this DT cord-286950-j7m69833 159 15 - - : cord-286950-j7m69833 159 16 to to IN cord-286950-j7m69833 159 17 the the DT cord-286950-j7m69833 159 18 homespun homespun JJ cord-286950-j7m69833 159 19 idea idea NN cord-286950-j7m69833 159 20 of of IN cord-286950-j7m69833 159 21 prudence prudence NN cord-286950-j7m69833 159 22 . . . cord-286950-j7m69833 160 1 But but CC cord-286950-j7m69833 160 2 prudence prudence NN cord-286950-j7m69833 160 3 is be VBZ cord-286950-j7m69833 160 4 really really RB cord-286950-j7m69833 160 5 a a DT cord-286950-j7m69833 160 6 simple simple JJ cord-286950-j7m69833 160 7 idea idea NN cord-286950-j7m69833 160 8 , , , cord-286950-j7m69833 160 9 familiar familiar JJ cord-286950-j7m69833 160 10 to to IN cord-286950-j7m69833 160 11 us -PRON- PRP cord-286950-j7m69833 160 12 all all DT cord-286950-j7m69833 160 13 . . . cord-286950-j7m69833 161 1 It -PRON- PRP cord-286950-j7m69833 161 2 means mean VBZ cord-286950-j7m69833 161 3 , , , cord-286950-j7m69833 161 4 " " '' cord-286950-j7m69833 161 5 think think VB cord-286950-j7m69833 161 6 before before IN cord-286950-j7m69833 161 7 you -PRON- PRP cord-286950-j7m69833 161 8 act act VBP cord-286950-j7m69833 161 9 " " '' cord-286950-j7m69833 161 10 and and CC cord-286950-j7m69833 161 11 " " `` cord-286950-j7m69833 161 12 do do VBP cord-286950-j7m69833 161 13 not not RB cord-286950-j7m69833 161 14 act act VB cord-286950-j7m69833 161 15 if if IN cord-286950-j7m69833 161 16 you -PRON- PRP cord-286950-j7m69833 161 17 are be VBP cord-286950-j7m69833 161 18 not not RB cord-286950-j7m69833 161 19 sufficiently sufficiently RB cord-286950-j7m69833 161 20 secure secure JJ cord-286950-j7m69833 161 21 in in IN cord-286950-j7m69833 161 22 thinking thinking NN cord-286950-j7m69833 161 23 that that IN cord-286950-j7m69833 161 24 you -PRON- PRP cord-286950-j7m69833 161 25 will will MD cord-286950-j7m69833 161 26 do do VB cord-286950-j7m69833 161 27 more more RBR cord-286950-j7m69833 161 28 good good JJ cord-286950-j7m69833 161 29 than than IN cord-286950-j7m69833 161 30 harm harm NN cord-286950-j7m69833 161 31 . . . cord-286950-j7m69833 161 32 " " '' cord-286950-j7m69833 162 1 Thinking think VBG cord-286950-j7m69833 162 2 before before IN cord-286950-j7m69833 162 3 acting acting NN cord-286950-j7m69833 162 4 should should MD cord-286950-j7m69833 162 5 include include VB cord-286950-j7m69833 162 6 risk risk NN cord-286950-j7m69833 162 7 analysis analysis NN cord-286950-j7m69833 162 8 in in IN cord-286950-j7m69833 162 9 settings setting NNS cord-286950-j7m69833 162 10 such such JJ cord-286950-j7m69833 162 11 as as IN cord-286950-j7m69833 162 12 GOF GOF NNP cord-286950-j7m69833 162 13 research research NN cord-286950-j7m69833 162 14 . . . cord-286950-j7m69833 163 1 But but CC cord-286950-j7m69833 163 2 a a DT cord-286950-j7m69833 163 3 risk risk NN cord-286950-j7m69833 163 4 analysis analysis NN cord-286950-j7m69833 163 5 is be VBZ cord-286950-j7m69833 163 6 not not RB cord-286950-j7m69833 163 7 the the DT cord-286950-j7m69833 163 8 end end NN cord-286950-j7m69833 163 9 of of IN cord-286950-j7m69833 163 10 clear clear JJ cord-286950-j7m69833 163 11 thinking thinking NN cord-286950-j7m69833 163 12 ; ; : cord-286950-j7m69833 163 13 it -PRON- PRP cord-286950-j7m69833 163 14 is be VBZ cord-286950-j7m69833 163 15 only only RB cord-286950-j7m69833 163 16 the the DT cord-286950-j7m69833 163 17 beginning beginning NN cord-286950-j7m69833 163 18 . . . cord-286950-j7m69833 164 1 Where where WRB cord-286950-j7m69833 164 2 does do VBZ cord-286950-j7m69833 164 3 this this DT cord-286950-j7m69833 164 4 leave leave VB cord-286950-j7m69833 164 5 us -PRON- PRP cord-286950-j7m69833 164 6 ? ? . cord-286950-j7m69833 165 1 One one CD cord-286950-j7m69833 165 2 major major JJ cord-286950-j7m69833 165 3 conclusion conclusion NN cord-286950-j7m69833 165 4 is be VBZ cord-286950-j7m69833 165 5 this this DT cord-286950-j7m69833 165 6 : : : cord-286950-j7m69833 166 1 For for IN cord-286950-j7m69833 166 2 almost almost RB cord-286950-j7m69833 166 3 every every DT cord-286950-j7m69833 166 4 form form NN cord-286950-j7m69833 166 5 of of IN cord-286950-j7m69833 166 6 human human JJ cord-286950-j7m69833 166 7 activity activity NN cord-286950-j7m69833 166 8 , , , cord-286950-j7m69833 166 9 there there EX cord-286950-j7m69833 166 10 is be VBZ cord-286950-j7m69833 166 11 a a DT cord-286950-j7m69833 166 12 nonvanishing nonvanishing JJ cord-286950-j7m69833 166 13 probability probability NN cord-286950-j7m69833 166 14 of of IN cord-286950-j7m69833 166 15 catastrophic catastrophic JJ cord-286950-j7m69833 166 16 outcomes outcome NNS cord-286950-j7m69833 166 17 . . . cord-286950-j7m69833 167 1 Any any DT cord-286950-j7m69833 167 2 casual casual JJ cord-286950-j7m69833 167 3 individual individual JJ cord-286950-j7m69833 167 4 act act NN cord-286950-j7m69833 167 5 could could MD cord-286950-j7m69833 167 6 set set VB cord-286950-j7m69833 167 7 in in IN cord-286950-j7m69833 167 8 motion motion NN cord-286950-j7m69833 167 9 a a DT cord-286950-j7m69833 167 10 chain chain NN cord-286950-j7m69833 167 11 of of IN cord-286950-j7m69833 167 12 events event NNS cord-286950-j7m69833 167 13 that that WDT cord-286950-j7m69833 167 14 would would MD cord-286950-j7m69833 167 15 lead lead VB cord-286950-j7m69833 167 16 to to IN cord-286950-j7m69833 167 17 the the DT cord-286950-j7m69833 167 18 rise rise NN cord-286950-j7m69833 167 19 of of IN cord-286950-j7m69833 167 20 the the DT cord-286950-j7m69833 167 21 next next JJ cord-286950-j7m69833 167 22 world world NN cord-286950-j7m69833 167 23 war war NN cord-286950-j7m69833 167 24 . . . cord-286950-j7m69833 168 1 This this DT cord-286950-j7m69833 168 2 is be VBZ cord-286950-j7m69833 168 3 highly highly RB cord-286950-j7m69833 168 4 improbable improbable JJ cord-286950-j7m69833 168 5 but but CC cord-286950-j7m69833 168 6 possible possible JJ cord-286950-j7m69833 168 7 , , , cord-286950-j7m69833 168 8 and and CC cord-286950-j7m69833 168 9 the the DT cord-286950-j7m69833 168 10 consequences consequence NNS cord-286950-j7m69833 168 11 would would MD cord-286950-j7m69833 168 12 be be VB cord-286950-j7m69833 168 13 cataclysmic cataclysmic JJ cord-286950-j7m69833 168 14 , , , cord-286950-j7m69833 168 15 outweighing outweigh VBG cord-286950-j7m69833 168 16 any any DT cord-286950-j7m69833 168 17 imaginable imaginable NN cord-286950-j7m69833 168 18 good good NN cord-286950-j7m69833 168 19 that that WDT cord-286950-j7m69833 168 20 might may MD cord-286950-j7m69833 168 21 derive derive VB cord-286950-j7m69833 168 22 from from IN cord-286950-j7m69833 168 23 that that DT cord-286950-j7m69833 168 24 action action NN cord-286950-j7m69833 168 25 . . . cord-286950-j7m69833 169 1 Therefore therefore RB cord-286950-j7m69833 169 2 , , , cord-286950-j7m69833 169 3 the the DT cord-286950-j7m69833 169 4 precautionary precautionary JJ cord-286950-j7m69833 169 5 principle principle NN cord-286950-j7m69833 169 6 would would MD cord-286950-j7m69833 169 7 suggest suggest VB cord-286950-j7m69833 169 8 that that IN cord-286950-j7m69833 169 9 we -PRON- PRP cord-286950-j7m69833 169 10 do do VBP cord-286950-j7m69833 169 11 nothing nothing NN cord-286950-j7m69833 169 12 . . . cord-286950-j7m69833 170 1 But but CC cord-286950-j7m69833 170 2 doing do VBG cord-286950-j7m69833 170 3 nothing nothing NN cord-286950-j7m69833 170 4 can can MD cord-286950-j7m69833 170 5 equally equally RB cord-286950-j7m69833 170 6 well well RB cord-286950-j7m69833 170 7 engender engender VB cord-286950-j7m69833 170 8 a a DT cord-286950-j7m69833 170 9 sequence sequence NN cord-286950-j7m69833 170 10 of of IN cord-286950-j7m69833 170 11 events event NNS cord-286950-j7m69833 170 12 leading lead VBG cord-286950-j7m69833 170 13 to to IN cord-286950-j7m69833 170 14 human human JJ cord-286950-j7m69833 170 15 extinction extinction NN cord-286950-j7m69833 170 16 . . . cord-286950-j7m69833 171 1 We -PRON- PRP cord-286950-j7m69833 171 2 conclude conclude VBP cord-286950-j7m69833 171 3 , , , cord-286950-j7m69833 171 4 therefore therefore RB cord-286950-j7m69833 171 5 , , , cord-286950-j7m69833 171 6 one one PRP cord-286950-j7m69833 171 7 should should MD cord-286950-j7m69833 171 8 act act VB cord-286950-j7m69833 171 9 . . . cord-286950-j7m69833 172 1 This this DT cord-286950-j7m69833 172 2 dilemma dilemma NN cord-286950-j7m69833 172 3 highlights highlight VBZ cord-286950-j7m69833 172 4 a a DT cord-286950-j7m69833 172 5 fatal fatal JJ cord-286950-j7m69833 172 6 contradiction contradiction NN cord-286950-j7m69833 172 7 lurking lurk VBG cord-286950-j7m69833 172 8 within within IN cord-286950-j7m69833 172 9 any any DT cord-286950-j7m69833 172 10 attempt attempt NN cord-286950-j7m69833 172 11 to to TO cord-286950-j7m69833 172 12 rationally rationally RB cord-286950-j7m69833 172 13 assess assess VB cord-286950-j7m69833 172 14 actions action NNS cord-286950-j7m69833 172 15 that that WDT cord-286950-j7m69833 172 16 might may MD cord-286950-j7m69833 172 17 entrain entrain VB cord-286950-j7m69833 172 18 consequences consequence NNS cord-286950-j7m69833 172 19 with with IN cord-286950-j7m69833 172 20 infinite infinite JJ cord-286950-j7m69833 172 21 negative negative JJ cord-286950-j7m69833 172 22 utility utility NN cord-286950-j7m69833 172 23 via via IN cord-286950-j7m69833 172 24 cost cost NN cord-286950-j7m69833 172 25 - - HYPH cord-286950-j7m69833 172 26 benefit benefit NN cord-286950-j7m69833 172 27 analysis analysis NN cord-286950-j7m69833 172 28 . . . cord-286950-j7m69833 173 1 How how WRB cord-286950-j7m69833 173 2 otherwise otherwise RB cord-286950-j7m69833 173 3 should should MD cord-286950-j7m69833 173 4 we -PRON- PRP cord-286950-j7m69833 173 5 proceed proceed VB cord-286950-j7m69833 173 6 ? ? . cord-286950-j7m69833 174 1 This this DT cord-286950-j7m69833 174 2 is be VBZ cord-286950-j7m69833 174 3 not not RB cord-286950-j7m69833 174 4 a a DT cord-286950-j7m69833 174 5 hard hard JJ cord-286950-j7m69833 174 6 question question NN cord-286950-j7m69833 174 7 . . . cord-286950-j7m69833 175 1 Think think VB cord-286950-j7m69833 175 2 about about IN cord-286950-j7m69833 175 3 both both DT cord-286950-j7m69833 175 4 risks risk NNS cord-286950-j7m69833 175 5 and and CC cord-286950-j7m69833 175 6 benefits benefit NNS cord-286950-j7m69833 175 7 , , , cord-286950-j7m69833 175 8 take take VB cord-286950-j7m69833 175 9 obvious obvious JJ cord-286950-j7m69833 175 10 precautions precaution NNS cord-286950-j7m69833 175 11 , , , cord-286950-j7m69833 175 12 and and CC cord-286950-j7m69833 175 13 then then RB cord-286950-j7m69833 175 14 make make VB cord-286950-j7m69833 175 15 the the DT cord-286950-j7m69833 175 16 prudent prudent JJ cord-286950-j7m69833 175 17 choice choice NN cord-286950-j7m69833 175 18 . . . cord-286950-j7m69833 176 1 With with IN cord-286950-j7m69833 176 2 enhanced enhance VBN cord-286950-j7m69833 176 3 biosafety biosafety NN cord-286950-j7m69833 176 4 protocols protocol NNS cord-286950-j7m69833 176 5 and and CC cord-286950-j7m69833 176 6 improvements improvement NNS cord-286950-j7m69833 176 7 in in IN cord-286950-j7m69833 176 8 the the DT cord-286950-j7m69833 176 9 public public JJ cord-286950-j7m69833 176 10 health health NN cord-286950-j7m69833 176 11 response response NN cord-286950-j7m69833 176 12 , , , cord-286950-j7m69833 176 13 we -PRON- PRP cord-286950-j7m69833 176 14 should should MD cord-286950-j7m69833 176 15 not not RB cord-286950-j7m69833 176 16 ban ban VB cord-286950-j7m69833 176 17 GOF GOF NNP cord-286950-j7m69833 176 18 research research NN cord-286950-j7m69833 176 19 but but CC cord-286950-j7m69833 176 20 monitor monitor VBP cord-286950-j7m69833 176 21 it -PRON- PRP cord-286950-j7m69833 176 22 . . . cord-286950-j7m69833 177 1 The the DT cord-286950-j7m69833 177 2 relevant relevant JJ cord-286950-j7m69833 177 3 research research NN cord-286950-j7m69833 177 4 communities community NNS cord-286950-j7m69833 177 5 should should MD cord-286950-j7m69833 177 6 insist insist VB cord-286950-j7m69833 177 7 upon upon IN cord-286950-j7m69833 177 8 stringent stringent JJ cord-286950-j7m69833 177 9 norms norm NNS cord-286950-j7m69833 177 10 for for IN cord-286950-j7m69833 177 11 the the DT cord-286950-j7m69833 177 12 conduct conduct NN cord-286950-j7m69833 177 13 of of IN cord-286950-j7m69833 177 14 the the DT cord-286950-j7m69833 177 15 research research NN cord-286950-j7m69833 177 16 and and CC cord-286950-j7m69833 177 17 in in IN cord-286950-j7m69833 177 18 safety safety NN cord-286950-j7m69833 177 19 protocols protocol NNS cord-286950-j7m69833 177 20 . . . cord-286950-j7m69833 178 1 Provided provide VBN cord-286950-j7m69833 178 2 that that IN cord-286950-j7m69833 178 3 these these DT cord-286950-j7m69833 178 4 conditions condition NNS cord-286950-j7m69833 178 5 are be VBP cord-286950-j7m69833 178 6 met meet VBN cord-286950-j7m69833 178 7 , , , cord-286950-j7m69833 178 8 there there EX cord-286950-j7m69833 178 9 is be VBZ cord-286950-j7m69833 178 10 no no DT cord-286950-j7m69833 178 11 obvious obvious JJ cord-286950-j7m69833 178 12 reason reason NN cord-286950-j7m69833 178 13 why why WRB cord-286950-j7m69833 178 14 GOF GOF NNP cord-286950-j7m69833 178 15 type type NN cord-286950-j7m69833 178 16 of of IN cord-286950-j7m69833 178 17 experimentation experimentation NN cord-286950-j7m69833 178 18 should should MD cord-286950-j7m69833 178 19 not not RB cord-286950-j7m69833 178 20 go go VB cord-286950-j7m69833 178 21 forward forward RB cord-286950-j7m69833 178 22 . . . cord-286950-j7m69833 179 1 Reconstruction reconstruction NN cord-286950-j7m69833 179 2 of of IN cord-286950-j7m69833 179 3 the the DT cord-286950-j7m69833 179 4 1918 1918 CD cord-286950-j7m69833 179 5 influenza influenza NN cord-286950-j7m69833 179 6 virus virus NN cord-286950-j7m69833 179 7 : : : cord-286950-j7m69833 179 8 unexpected unexpected JJ cord-286950-j7m69833 179 9 rewards reward NNS cord-286950-j7m69833 179 10 from from IN cord-286950-j7m69833 179 11 the the DT cord-286950-j7m69833 179 12 past past NN cord-286950-j7m69833 180 1 Better well RBR cord-286950-j7m69833 180 2 never never RB cord-286950-j7m69833 180 3 than than IN cord-286950-j7m69833 180 4 late late JJ cord-286950-j7m69833 180 5 Airborne airborne JJ cord-286950-j7m69833 180 6 transmission transmission NN cord-286950-j7m69833 180 7 of of IN cord-286950-j7m69833 180 8 influenza influenza NN cord-286950-j7m69833 180 9 A A NNP cord-286950-j7m69833 180 10 / / SYM cord-286950-j7m69833 180 11 H5N1 H5N1 NNP cord-286950-j7m69833 180 12 virus virus NN cord-286950-j7m69833 180 13 between between IN cord-286950-j7m69833 180 14 ferrets ferret NNS cord-286950-j7m69833 180 15 Experimental experimental JJ cord-286950-j7m69833 180 16 adaptation adaptation NN cord-286950-j7m69833 180 17 of of IN cord-286950-j7m69833 180 18 an an DT cord-286950-j7m69833 180 19 influenza influenza NN cord-286950-j7m69833 180 20 H5 H5 NNP cord-286950-j7m69833 180 21 HA HA NNP cord-286950-j7m69833 180 22 confers confer VBZ cord-286950-j7m69833 180 23 respiratory respiratory JJ cord-286950-j7m69833 180 24 droplet droplet NN cord-286950-j7m69833 180 25 transmission transmission NN cord-286950-j7m69833 180 26 to to IN cord-286950-j7m69833 180 27 a a DT cord-286950-j7m69833 180 28 reassortant reassortant JJ cord-286950-j7m69833 180 29 H5 H5 NNP cord-286950-j7m69833 180 30 HA HA NNP cord-286950-j7m69833 180 31 / / SYM cord-286950-j7m69833 180 32 H1N1 H1N1 NNP cord-286950-j7m69833 180 33 virus virus NN cord-286950-j7m69833 180 34 in in IN cord-286950-j7m69833 180 35 ferrets ferret NNS cord-286950-j7m69833 180 36 Public public JJ cord-286950-j7m69833 180 37 health health NN cord-286950-j7m69833 180 38 and and CC cord-286950-j7m69833 180 39 biosecurity biosecurity NN cord-286950-j7m69833 180 40 . . . cord-286950-j7m69833 181 1 Adaptations adaptation NNS cord-286950-j7m69833 181 2 of of IN cord-286950-j7m69833 181 3 avian avian JJ cord-286950-j7m69833 181 4 flu flu NN cord-286950-j7m69833 181 5 virus virus NN cord-286950-j7m69833 181 6 are be VBP cord-286950-j7m69833 181 7 a a DT cord-286950-j7m69833 181 8 cause cause NN cord-286950-j7m69833 181 9 for for IN cord-286950-j7m69833 181 10 concern concern NN cord-286950-j7m69833 182 1 Circulating circulate VBG cord-286950-j7m69833 182 2 avian avian JJ cord-286950-j7m69833 182 3 influenza influenza NN cord-286950-j7m69833 182 4 viruses virus NNS cord-286950-j7m69833 182 5 closely closely RB cord-286950-j7m69833 182 6 related relate VBN cord-286950-j7m69833 182 7 to to IN cord-286950-j7m69833 182 8 the the DT cord-286950-j7m69833 182 9 1918 1918 CD cord-286950-j7m69833 182 10 virus virus NN cord-286950-j7m69833 182 11 have have VBP cord-286950-j7m69833 182 12 pandemic pandemic NN cord-286950-j7m69833 182 13 potential potential JJ cord-286950-j7m69833 182 14 A a DT cord-286950-j7m69833 182 15 new new JJ cord-286950-j7m69833 182 16 synthesis synthesis NN cord-286950-j7m69833 182 17 for for IN cord-286950-j7m69833 182 18 dual dual JJ cord-286950-j7m69833 182 19 use use NN cord-286950-j7m69833 182 20 research research NN cord-286950-j7m69833 182 21 of of IN cord-286950-j7m69833 182 22 concern concern NN cord-286950-j7m69833 182 23 Zika Zika NNP cord-286950-j7m69833 182 24 virus virus NN cord-286950-j7m69833 182 25 focuses focus VBZ cord-286950-j7m69833 182 26 the the DT cord-286950-j7m69833 182 27 gain gain NN cord-286950-j7m69833 182 28 - - HYPH cord-286950-j7m69833 182 29 of of IN cord-286950-j7m69833 182 30 - - HYPH cord-286950-j7m69833 182 31 function function NN cord-286950-j7m69833 182 32 debate debate NN cord-286950-j7m69833 183 1 An an DT cord-286950-j7m69833 183 2 epistemological epistemological JJ cord-286950-j7m69833 183 3 perspective perspective NN cord-286950-j7m69833 183 4 on on IN cord-286950-j7m69833 183 5 the the DT cord-286950-j7m69833 183 6 value value NN cord-286950-j7m69833 183 7 of of IN cord-286950-j7m69833 183 8 gain gain NN cord-286950-j7m69833 183 9 - - HYPH cord-286950-j7m69833 183 10 of of IN cord-286950-j7m69833 183 11 - - HYPH cord-286950-j7m69833 183 12 function function NN cord-286950-j7m69833 183 13 experiments experiment NNS cord-286950-j7m69833 183 14 involving involve VBG cord-286950-j7m69833 183 15 pathogens pathogen NNS cord-286950-j7m69833 183 16 with with IN cord-286950-j7m69833 183 17 pandemic pandemic NN cord-286950-j7m69833 183 18 potential potential JJ cord-286950-j7m69833 183 19 Risks risk NNS cord-286950-j7m69833 183 20 and and CC cord-286950-j7m69833 183 21 benefits benefit NNS cord-286950-j7m69833 183 22 of of IN cord-286950-j7m69833 183 23 gain gain NN cord-286950-j7m69833 183 24 - - HYPH cord-286950-j7m69833 183 25 of of IN cord-286950-j7m69833 183 26 - - HYPH cord-286950-j7m69833 183 27 function function NN cord-286950-j7m69833 183 28 experiments experiment NNS cord-286950-j7m69833 183 29 with with IN cord-286950-j7m69833 183 30 pathogens pathogen NNS cord-286950-j7m69833 183 31 of of IN cord-286950-j7m69833 183 32 pandemic pandemic NN cord-286950-j7m69833 183 33 potential potential NN cord-286950-j7m69833 183 34 , , , cord-286950-j7m69833 183 35 such such JJ cord-286950-j7m69833 183 36 as as IN cord-286950-j7m69833 183 37 influenza influenza NN cord-286950-j7m69833 183 38 virus virus NN cord-286950-j7m69833 183 39 : : : cord-286950-j7m69833 183 40 a a DT cord-286950-j7m69833 183 41 call call NN cord-286950-j7m69833 183 42 for for IN cord-286950-j7m69833 183 43 a a DT cord-286950-j7m69833 183 44 science science NN cord-286950-j7m69833 183 45 - - HYPH cord-286950-j7m69833 183 46 based base VBN cord-286950-j7m69833 183 47 discussion discussion NN cord-286950-j7m69833 183 48 Airborne airborne JJ cord-286950-j7m69833 183 49 transmission transmission NN cord-286950-j7m69833 183 50 of of IN cord-286950-j7m69833 183 51 highly highly RB cord-286950-j7m69833 183 52 pathogenic pathogenic JJ cord-286950-j7m69833 183 53 H7N1 H7N1 NNP cord-286950-j7m69833 183 54 influenza influenza NN cord-286950-j7m69833 183 55 virus virus NN cord-286950-j7m69833 183 56 in in IN cord-286950-j7m69833 183 57 ferrets ferret NNS cord-286950-j7m69833 184 1 The the DT cord-286950-j7m69833 184 2 pH ph NN cord-286950-j7m69833 184 3 of of IN cord-286950-j7m69833 184 4 activation activation NN cord-286950-j7m69833 184 5 of of IN cord-286950-j7m69833 184 6 the the DT cord-286950-j7m69833 184 7 hemagglutinin hemagglutinin NN cord-286950-j7m69833 184 8 protein protein NN cord-286950-j7m69833 184 9 regulates regulate VBZ cord-286950-j7m69833 184 10 H5N1 H5N1 NNP cord-286950-j7m69833 184 11 influenza influenza NN cord-286950-j7m69833 184 12 virus virus NN cord-286950-j7m69833 184 13 replication replication NN cord-286950-j7m69833 184 14 and and CC cord-286950-j7m69833 184 15 pathogenesis pathogenesis NN cord-286950-j7m69833 184 16 in in IN cord-286950-j7m69833 184 17 mice mice NN cord-286950-j7m69833 184 18 Development Development NNP cord-286950-j7m69833 184 19 of of IN cord-286950-j7m69833 184 20 high high JJ cord-286950-j7m69833 184 21 - - HYPH cord-286950-j7m69833 184 22 yield yield NN cord-286950-j7m69833 184 23 influenza influenza NN cord-286950-j7m69833 184 24 A a DT cord-286950-j7m69833 184 25 virus virus NN cord-286950-j7m69833 184 26 vaccine vaccine NN cord-286950-j7m69833 184 27 viruses virus NNS cord-286950-j7m69833 184 28 Use use VBP cord-286950-j7m69833 184 29 of of IN cord-286950-j7m69833 184 30 highly highly RB cord-286950-j7m69833 184 31 pathogenic pathogenic JJ cord-286950-j7m69833 184 32 avian avian JJ cord-286950-j7m69833 184 33 influenza influenza NN cord-286950-j7m69833 184 34 A(H5N1 A(H5N1 NNP cord-286950-j7m69833 184 35 ) ) -RRB- cord-286950-j7m69833 184 36 gain gain NN cord-286950-j7m69833 184 37 - - HYPH cord-286950-j7m69833 184 38 of of IN cord-286950-j7m69833 184 39 - - HYPH cord-286950-j7m69833 184 40 function function NN cord-286950-j7m69833 184 41 studies study NNS cord-286950-j7m69833 184 42 for for IN cord-286950-j7m69833 184 43 molecular molecular NN cord-286950-j7m69833 184 44 - - HYPH cord-286950-j7m69833 184 45 based base VBN cord-286950-j7m69833 184 46 surveillance surveillance NN cord-286950-j7m69833 184 47 and and CC cord-286950-j7m69833 184 48 pandemic pandemic NN cord-286950-j7m69833 184 49 preparedness preparedness NN cord-286950-j7m69833 184 50 Influenza Influenza NNP cord-286950-j7m69833 184 51 gain gain NN cord-286950-j7m69833 184 52 - - HYPH cord-286950-j7m69833 184 53 of of IN cord-286950-j7m69833 184 54 - - HYPH cord-286950-j7m69833 184 55 function function NN cord-286950-j7m69833 184 56 experiments experiment NNS cord-286950-j7m69833 184 57 : : : cord-286950-j7m69833 184 58 their -PRON- PRP$ cord-286950-j7m69833 184 59 role role NN cord-286950-j7m69833 184 60 in in IN cord-286950-j7m69833 184 61 vaccine vaccine NN cord-286950-j7m69833 184 62 virus virus NN cord-286950-j7m69833 184 63 recommendation recommendation NN cord-286950-j7m69833 184 64 and and CC cord-286950-j7m69833 184 65 pandemic pandemic NN cord-286950-j7m69833 184 66 preparedness preparedness NN cord-286950-j7m69833 184 67 Ethical ethical JJ cord-286950-j7m69833 184 68 alternatives alternative NNS cord-286950-j7m69833 184 69 to to IN cord-286950-j7m69833 184 70 experiments experiment NNS cord-286950-j7m69833 184 71 with with IN cord-286950-j7m69833 184 72 novel novel JJ cord-286950-j7m69833 184 73 potential potential JJ cord-286950-j7m69833 184 74 pandemic pandemic NN cord-286950-j7m69833 184 75 pathogens pathogen NNS cord-286950-j7m69833 184 76 Gain gain VB cord-286950-j7m69833 184 77 - - HYPH cord-286950-j7m69833 184 78 of of IN cord-286950-j7m69833 184 79 - - HYPH cord-286950-j7m69833 184 80 function function NN cord-286950-j7m69833 184 81 research research NN cord-286950-j7m69833 184 82 : : : cord-286950-j7m69833 184 83 unproven unproven JJ cord-286950-j7m69833 184 84 technique technique NN cord-286950-j7m69833 184 85 Structural structural JJ cord-286950-j7m69833 184 86 determinants determinant NNS cord-286950-j7m69833 184 87 for for IN cord-286950-j7m69833 184 88 naturally naturally RB cord-286950-j7m69833 184 89 evolving evolve VBG cord-286950-j7m69833 184 90 H5N1 H5N1 NNP cord-286950-j7m69833 184 91 hemagglutinin hemagglutinin NN cord-286950-j7m69833 184 92 to to TO cord-286950-j7m69833 184 93 switch switch VB cord-286950-j7m69833 184 94 its -PRON- PRP$ cord-286950-j7m69833 184 95 receptor receptor NN cord-286950-j7m69833 184 96 specificity specificity NN cord-286950-j7m69833 184 97 Identification identification NN cord-286950-j7m69833 184 98 , , , cord-286950-j7m69833 184 99 characterization characterization NN cord-286950-j7m69833 184 100 , , , cord-286950-j7m69833 184 101 and and CC cord-286950-j7m69833 184 102 natural natural JJ cord-286950-j7m69833 184 103 selection selection NN cord-286950-j7m69833 184 104 of of IN cord-286950-j7m69833 184 105 mutations mutation NNS cord-286950-j7m69833 184 106 driving drive VBG cord-286950-j7m69833 184 107 airborne airborne JJ cord-286950-j7m69833 184 108 transmission transmission NN cord-286950-j7m69833 184 109 of of IN cord-286950-j7m69833 184 110 A A NNP cord-286950-j7m69833 184 111 / / SYM cord-286950-j7m69833 184 112 H5N1 H5N1 NNP cord-286950-j7m69833 184 113 virus virus NN cord-286950-j7m69833 184 114 Generation generation NN cord-286950-j7m69833 184 115 of of IN cord-286950-j7m69833 184 116 a a DT cord-286950-j7m69833 184 117 transgenic transgenic JJ cord-286950-j7m69833 184 118 mouse mouse NN cord-286950-j7m69833 184 119 model model NN cord-286950-j7m69833 184 120 of of IN cord-286950-j7m69833 184 121 Middle Middle NNP cord-286950-j7m69833 184 122 East East NNP cord-286950-j7m69833 184 123 respiratory respiratory JJ cord-286950-j7m69833 184 124 syndrome syndrome NN cord-286950-j7m69833 184 125 coronavirus coronavirus NN cord-286950-j7m69833 184 126 infection infection NN cord-286950-j7m69833 184 127 and and CC cord-286950-j7m69833 184 128 disease disease NN cord-286950-j7m69833 185 1 Middle Middle NNP cord-286950-j7m69833 185 2 east east NNP cord-286950-j7m69833 185 3 respiratory respiratory JJ cord-286950-j7m69833 185 4 syndrome syndrome NN cord-286950-j7m69833 185 5 coronavirus coronavirus NN cord-286950-j7m69833 185 6 causes cause VBZ cord-286950-j7m69833 185 7 multiple multiple JJ cord-286950-j7m69833 185 8 organ organ NN cord-286950-j7m69833 185 9 damage damage NN cord-286950-j7m69833 185 10 and and CC cord-286950-j7m69833 185 11 lethal lethal JJ cord-286950-j7m69833 185 12 disease disease NN cord-286950-j7m69833 185 13 in in IN cord-286950-j7m69833 185 14 mice mouse NNS cord-286950-j7m69833 185 15 transgenic transgenic JJ cord-286950-j7m69833 185 16 for for IN cord-286950-j7m69833 185 17 human human JJ cord-286950-j7m69833 185 18 dipeptidyl dipeptidyl JJ cord-286950-j7m69833 185 19 peptidase peptidase NN cord-286950-j7m69833 185 20 4 4 CD cord-286950-j7m69833 185 21 Mouse Mouse NNP cord-286950-j7m69833 185 22 - - HYPH cord-286950-j7m69833 185 23 adapted adapt VBN cord-286950-j7m69833 185 24 MERS MERS NNP cord-286950-j7m69833 185 25 coronavirus coronavirus NN cord-286950-j7m69833 185 26 causes cause VBZ cord-286950-j7m69833 185 27 lethal lethal JJ cord-286950-j7m69833 185 28 lung lung NN cord-286950-j7m69833 185 29 disease disease NN cord-286950-j7m69833 185 30 in in IN cord-286950-j7m69833 185 31 human human JJ cord-286950-j7m69833 185 32 DPP4 DPP4 NNP cord-286950-j7m69833 185 33 knockin knockin NN cord-286950-j7m69833 185 34 mice mouse NNS cord-286950-j7m69833 185 35 Multi multi JJ cord-286950-j7m69833 185 36 - - JJ cord-286950-j7m69833 185 37 organ organ NN cord-286950-j7m69833 185 38 damage damage NN cord-286950-j7m69833 185 39 in in IN cord-286950-j7m69833 185 40 human human JJ cord-286950-j7m69833 185 41 dipeptidyl dipeptidyl JJ cord-286950-j7m69833 185 42 peptidase peptidase NN cord-286950-j7m69833 185 43 4 4 CD cord-286950-j7m69833 185 44 transgenic transgenic JJ cord-286950-j7m69833 185 45 mice mouse NNS cord-286950-j7m69833 185 46 infected infect VBN cord-286950-j7m69833 185 47 with with IN cord-286950-j7m69833 185 48 middle middle NNP cord-286950-j7m69833 185 49 east east NNP cord-286950-j7m69833 185 50 respiratory respiratory JJ cord-286950-j7m69833 185 51 syndrome syndrome NN cord-286950-j7m69833 185 52 - - HYPH cord-286950-j7m69833 185 53 coronavirus coronavirus NN cord-286950-j7m69833 185 54 A a DT cord-286950-j7m69833 185 55 mouse mouse NN cord-286950-j7m69833 185 56 model model NN cord-286950-j7m69833 185 57 for for IN cord-286950-j7m69833 186 1 MERS MERS NNP cord-286950-j7m69833 186 2 coronavirus coronavirus NN cord-286950-j7m69833 186 3 - - HYPH cord-286950-j7m69833 186 4 induced induce VBN cord-286950-j7m69833 186 5 acute acute JJ cord-286950-j7m69833 186 6 respiratory respiratory JJ cord-286950-j7m69833 186 7 distress distress NN cord-286950-j7m69833 186 8 syndrome syndrome NN cord-286950-j7m69833 186 9 Broad Broad NNP cord-286950-j7m69833 186 10 - - HYPH cord-286950-j7m69833 186 11 spectrum spectrum NN cord-286950-j7m69833 186 12 antiviral antiviral JJ cord-286950-j7m69833 186 13 GS-5734 GS-5734 NNS cord-286950-j7m69833 186 14 inhibits inhibit VBZ cord-286950-j7m69833 186 15 both both DT cord-286950-j7m69833 186 16 epidemic epidemic NN cord-286950-j7m69833 186 17 and and CC cord-286950-j7m69833 186 18 zoonotic zoonotic JJ cord-286950-j7m69833 186 19 coronaviruses coronaviruse NNS cord-286950-j7m69833 186 20 Biosecurity Biosecurity NNP cord-286950-j7m69833 186 21 . . . cord-286950-j7m69833 187 1 U.S. U.S. NNP cord-286950-j7m69833 187 2 halts halt VBZ cord-286950-j7m69833 187 3 two two CD cord-286950-j7m69833 187 4 dozen dozen NN cord-286950-j7m69833 187 5 risky risky JJ cord-286950-j7m69833 187 6 virus virus NN cord-286950-j7m69833 187 7 studies study NNS cord-286950-j7m69833 188 1 The the DT cord-286950-j7m69833 188 2 Reemergent Reemergent NNP cord-286950-j7m69833 188 3 1977 1977 CD cord-286950-j7m69833 188 4 H1N1 H1N1 NNP cord-286950-j7m69833 188 5 strain strain NN cord-286950-j7m69833 188 6 and and CC cord-286950-j7m69833 188 7 the the DT cord-286950-j7m69833 188 8 gain gain NN cord-286950-j7m69833 188 9 - - HYPH cord-286950-j7m69833 188 10 of of IN cord-286950-j7m69833 188 11 - - HYPH cord-286950-j7m69833 188 12 function function NN cord-286950-j7m69833 188 13 debate debate NN cord-286950-j7m69833 188 14 Reply Reply NNP cord-286950-j7m69833 188 15 to to IN cord-286950-j7m69833 188 16 " " '' cord-286950-j7m69833 188 17 the the DT cord-286950-j7m69833 188 18 1977 1977 CD cord-286950-j7m69833 188 19 H1N1 H1N1 NNP cord-286950-j7m69833 188 20 influenza influenza NN cord-286950-j7m69833 188 21 virus virus NN cord-286950-j7m69833 188 22 reemergence reemergence NN cord-286950-j7m69833 188 23 demonstrated demonstrate VBD cord-286950-j7m69833 188 24 gain gain NN cord-286950-j7m69833 188 25 - - HYPH cord-286950-j7m69833 188 26 of of IN cord-286950-j7m69833 188 27 - - HYPH cord-286950-j7m69833 188 28 function function NN cord-286950-j7m69833 188 29 hazards hazard NNS cord-286950-j7m69833 189 1 The the DT cord-286950-j7m69833 189 2 1977 1977 CD cord-286950-j7m69833 189 3 H1N1 H1N1 NNP cord-286950-j7m69833 189 4 influenza influenza NN cord-286950-j7m69833 189 5 virus virus NN cord-286950-j7m69833 189 6 reemergence reemergence NN cord-286950-j7m69833 189 7 demonstrated demonstrate VBD cord-286950-j7m69833 189 8 gain gain NN cord-286950-j7m69833 189 9 - - HYPH cord-286950-j7m69833 189 10 offunction offunction NN cord-286950-j7m69833 189 11 hazards hazard NNS cord-286950-j7m69833 190 1 Three three CD cord-286950-j7m69833 190 2 mutations mutation NNS cord-286950-j7m69833 190 3 switch switch VBP cord-286950-j7m69833 190 4 H7N9 H7N9 NNP cord-286950-j7m69833 190 5 influenza influenza NN cord-286950-j7m69833 190 6 to to IN cord-286950-j7m69833 190 7 human human JJ cord-286950-j7m69833 190 8 - - HYPH cord-286950-j7m69833 190 9 type type NN cord-286950-j7m69833 190 10 receptor receptor NN cord-286950-j7m69833 190 11 specificity specificity NN cord-286950-j7m69833 190 12 Ethical ethical JJ cord-286950-j7m69833 190 13 issues issue NNS cord-286950-j7m69833 190 14 in in IN cord-286950-j7m69833 190 15 genome genome NN cord-286950-j7m69833 190 16 editing editing NN cord-286950-j7m69833 190 17 using use VBG cord-286950-j7m69833 190 18 CRISPR CRISPR NNP cord-286950-j7m69833 190 19 / / SYM cord-286950-j7m69833 190 20 Cas9 Cas9 NNP cord-286950-j7m69833 190 21 system system NN cord-286950-j7m69833 190 22 Dual Dual NNP cord-286950-j7m69833 190 23 - - : cord-286950-j7m69833 190 24 Use Use NNP cord-286950-j7m69833 190 25 Research Research NNP cord-286950-j7m69833 190 26 of of IN cord-286950-j7m69833 190 27 Concern Concern NNP cord-286950-j7m69833 190 28 ( ( -LRB- cord-286950-j7m69833 190 29 DURC DURC NNP cord-286950-j7m69833 190 30 ) ) -RRB- cord-286950-j7m69833 190 31 Review Review NNP cord-286950-j7m69833 190 32 at at IN cord-286950-j7m69833 190 33 American American NNP cord-286950-j7m69833 190 34 Society Society NNP cord-286950-j7m69833 190 35 for for IN cord-286950-j7m69833 190 36 microbiology microbiology NN cord-286950-j7m69833 190 37 journals journal NNS cord-286950-j7m69833 190 38 Biosecurity Biosecurity NNP cord-286950-j7m69833 190 39 and and CC cord-286950-j7m69833 190 40 the the DT cord-286950-j7m69833 190 41 review review NN cord-286950-j7m69833 190 42 and and CC cord-286950-j7m69833 190 43 publication publication NN cord-286950-j7m69833 190 44 of of IN cord-286950-j7m69833 190 45 dual dual JJ cord-286950-j7m69833 190 46 - - HYPH cord-286950-j7m69833 190 47 use use NN cord-286950-j7m69833 190 48 research research NN cord-286950-j7m69833 190 49 of of IN cord-286950-j7m69833 190 50 concern concern NN cord-286950-j7m69833 191 1 The the DT cord-286950-j7m69833 191 2 ethics ethic NNS cord-286950-j7m69833 191 3 of of IN cord-286950-j7m69833 191 4 biosafety biosafety NN cord-286950-j7m69833 191 5 considerations consideration NNS cord-286950-j7m69833 191 6 in in IN cord-286950-j7m69833 191 7 gainof gainof NN cord-286950-j7m69833 191 8 - - HYPH cord-286950-j7m69833 191 9 function function NN cord-286950-j7m69833 191 10 research research NN cord-286950-j7m69833 191 11 resulting result VBG cord-286950-j7m69833 191 12 in in IN cord-286950-j7m69833 191 13 the the DT cord-286950-j7m69833 191 14 creation creation NN cord-286950-j7m69833 191 15 of of IN cord-286950-j7m69833 191 16 potential potential JJ cord-286950-j7m69833 191 17 pandemic pandemic NN cord-286950-j7m69833 191 18 pathogens pathogen NNS cord-286950-j7m69833 191 19 Moratorium Moratorium NNP cord-286950-j7m69833 191 20 on on IN cord-286950-j7m69833 191 21 research research NN cord-286950-j7m69833 191 22 intended intend VBN cord-286950-j7m69833 191 23 to to TO cord-286950-j7m69833 191 24 create create VB cord-286950-j7m69833 191 25 novel novel JJ cord-286950-j7m69833 191 26 potential potential JJ cord-286950-j7m69833 191 27 pandemic pandemic NN cord-286950-j7m69833 191 28 pathogens pathogen NNS cord-286950-j7m69833 191 29 Erratum Erratum NNP cord-286950-j7m69833 191 30 for for IN cord-286950-j7m69833 191 31 Lipsitch Lipsitch NNP cord-286950-j7m69833 191 32 and and CC cord-286950-j7m69833 191 33 Inglesby Inglesby NNP cord-286950-j7m69833 191 34 , , , cord-286950-j7m69833 191 35 moratorium moratorium NN cord-286950-j7m69833 191 36 on on IN cord-286950-j7m69833 191 37 research research NN cord-286950-j7m69833 191 38 intended intend VBN cord-286950-j7m69833 191 39 to to TO cord-286950-j7m69833 191 40 create create VB cord-286950-j7m69833 191 41 novel novel JJ cord-286950-j7m69833 191 42 potential potential JJ cord-286950-j7m69833 191 43 pandemic pandemic NN cord-286950-j7m69833 191 44 pathogens pathogen NNS cord-286950-j7m69833 191 45 Studies Studies NNPS cord-286950-j7m69833 191 46 on on IN cord-286950-j7m69833 191 47 influenza influenza NN cord-286950-j7m69833 191 48 virus virus NN cord-286950-j7m69833 191 49 transmission transmission NN cord-286950-j7m69833 191 50 between between IN cord-286950-j7m69833 191 51 ferrets ferret NNS cord-286950-j7m69833 191 52 : : : cord-286950-j7m69833 191 53 the the DT cord-286950-j7m69833 191 54 public public JJ cord-286950-j7m69833 191 55 health health NN cord-286950-j7m69833 191 56 risks risk NNS cord-286950-j7m69833 191 57 revisited revisit VBD cord-286950-j7m69833 191 58 7 7 CD cord-286950-j7m69833 191 59 ) ) -RRB- cord-286950-j7m69833 192 1 Pandemic pandemic NN cord-286950-j7m69833 192 2 influenza influenza NN cord-286950-j7m69833 192 3 A A NNP cord-286950-j7m69833 192 4 / / SYM cord-286950-j7m69833 192 5 H1N1pdm H1N1pdm NNP cord-286950-j7m69833 192 6 in in IN cord-286950-j7m69833 192 7 Italy Italy NNP cord-286950-j7m69833 192 8 : : : cord-286950-j7m69833 192 9 age age NN cord-286950-j7m69833 192 10 , , , cord-286950-j7m69833 192 11 risk risk NN cord-286950-j7m69833 192 12 and and CC cord-286950-j7m69833 192 13 population population NN cord-286950-j7m69833 192 14 susceptibility susceptibility NN cord-286950-j7m69833 192 15 Technology technology NN cord-286950-j7m69833 192 16 and and CC cord-286950-j7m69833 192 17 the the DT cord-286950-j7m69833 192 18 virtues virtue NNS cord-286950-j7m69833 192 19 : : : cord-286950-j7m69833 192 20 a a DT cord-286950-j7m69833 192 21 philosophical philosophical JJ cord-286950-j7m69833 192 22 guide guide NN cord-286950-j7m69833 192 23 to to IN cord-286950-j7m69833 192 24 a a DT cord-286950-j7m69833 192 25 future future JJ cord-286950-j7m69833 192 26 worth worth JJ cord-286950-j7m69833 192 27 wanting want VBG cord-286950-j7m69833 192 28 The the DT cord-286950-j7m69833 192 29 apocalypse apocalypse NN cord-286950-j7m69833 192 30 as as IN cord-286950-j7m69833 192 31 a a DT cord-286950-j7m69833 192 32 rhetorical rhetorical JJ cord-286950-j7m69833 192 33 device device NN cord-286950-j7m69833 192 34 in in IN cord-286950-j7m69833 192 35 the the DT cord-286950-j7m69833 192 36 influenza influenza NN cord-286950-j7m69833 192 37 virus virus NN cord-286950-j7m69833 192 38 gain gain NN cord-286950-j7m69833 192 39 - - HYPH cord-286950-j7m69833 192 40 of of IN cord-286950-j7m69833 192 41 - - HYPH cord-286950-j7m69833 192 42 function function NN cord-286950-j7m69833 192 43 debate debate NN