id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-048197-9785vg6d	Domachowske, Joseph B	Gene expression in epithelial cells in response to pneumovirus infection	2001-05-11		.txt	text/plain	4688	193	34	The respiratory epithelial target cells respond to viral infection with specific alterations in gene expression, including production of chemoattractant cytokines, adhesion molecules, elements that are related to the apoptosis response, and others that remain incompletely understood. The transcription factor NF-IL-6 is also produced in response to RSV infection [13] , and participates in a co-operative manner with NF-κB in the regulation of IL-8 gene expression [11] , although later studies suggest that activator protein-1 may function preferentially in this role [14] . Again, as part of our systematic study of gene expression in response to pneumovirus infection, we found that human respiratory epithelial cells respond to RSV infection with increased expression of the cytoskeletal protein cytokeratin-17 [36] . Inhibiton of viral replication reverses respiratory syncytial virus-induced NF-κ κB activation and interleukin-8 gene expression in A549 cells Respiratory syncytial virus infection induces expression of the anti-apoptosis gene IEX-1L in human respiratory epithelial cells	./cache/cord-048197-9785vg6d.txt	./txt/cord-048197-9785vg6d.txt