id author title date pages extension mime words sentences flesch summary cache txt cord-284905-h8xovybl MUSK, A.W. (Bill) Respiratory infections and lung function in an Australian Aboriginal community 2008-02-05 .txt text/plain 3449 178 43 Background and objective: To investigate the association between serological evidence of past infections with common respiratory pathogens and lung function in members of an isolated community of Aborigines from tropical coastal north‐western Australia. 3 Studies of members of an isolated coastal Australian Aboriginal community in the tropical Kimberley region of Western Australia have shown that levels of lung function measured by FEV1 and FVC were lower than those of Australians of European descent. In this tropical Aboriginal community, serological evidence of the burden of previous infections with known viral and other respiratory pathogens was associated with significant decreases in the levels of airway function, consistent with airflow obstruction. The relationship of FEV1 and FEV1/FVC ratio with the total number of positive titres in this study suggests that repeated infections with common respiratory pathogens may have a cumulative detrimental effect on airway function or increase susceptibility to other agents such as tobacco smoke. ./cache/cord-284905-h8xovybl.txt ./txt/cord-284905-h8xovybl.txt