id author title date pages extension mime words sentences flesch summary cache txt cord-291217-fpte1q9m Adams, Madeleine Management of bronchiolitis 2009-05-13 .txt text/plain 3536 153 32 The most recent Cochrane review of 22 trials involving 1428 infants with bronchiolitis who received inhaled bronchodilators (including β 2 agonists, ipratropium and adrenergic agents) reported a significant improvement in overall average clinical score, but had no effect on either pulse oximetry measurements or on risk of hospitalization. However, a recent placebo-controlled study of montelukast in 53 infants with a first episode of bronchiolitis demonstrated absence of benefit, with no significant differences in length of hospitalization, clinical severity score, or inflammatory mediators between the two groups. Fluids (either enteral or parenteral) and oxygen are the mainstays, although cpap or mechanical ventilation are effective for respiratory failure • there is no role for bronchodilators, corticosteroids, antiviral agents, physiotherapy, nebulized dnase or antibiotics, but nebulized 3% hypertonic saline administered with a bronchodilator may decrease length of stay in hospital ./cache/cord-291217-fpte1q9m.txt ./txt/cord-291217-fpte1q9m.txt