id author title date pages extension mime words sentences flesch summary cache txt cord-254549-ev0oesu0 Kutikhin, Anton G C-type lectin receptors and RIG-I-like receptors: new points on the oncogenomics map 2012-02-24 .txt text/plain 4446 180 36 The fundamental basis for the association of the inherited coding variation in genes encoding C-type lectin receptors and RIG-I-like receptors with cancer is represented by the defects in the immune response (that are caused by various single nucleotide polymorphisms) against specific carcinogenic infectious agents. The issue of an association of single nucleotide polymorphisms of genes encoding C-type lectin receptors, RIG-I-like receptors, and proteins of pattern recognition receptor pathways with various features of cancer progression is open, and only further population studies would be likely to give a definite answer. Another interesting issue is that associations between single nucleotide polymorphisms of genes encoding C-type lectin receptors and RIG-I-like receptors and cancer risk can be skewed by differences between cohorts in various immune responses and infections that may not influence cancer development. ./cache/cord-254549-ev0oesu0.txt ./txt/cord-254549-ev0oesu0.txt