id author title date pages extension mime words sentences flesch summary cache txt cord-006951-tj22dh5o Li, Siyu The effect of RNA stiffness on the self-assembly of virus particles 2018-01-31 .txt text/plain 4913 218 59 While viral RNAs are found to be compact and highly branched because of long distance base-pairing between nucleotides, recent experiments reveal that in a head-to-head competition between an ssRNA with no secondary or higher order structure and a viral RNA, the capsid proteins preferentially encapsulate the linear polymer! While branching makes the genome more compact, RNA base-pairing increases the effective Kuhn length of the RNA molecule, which could result in an increase of the free energy of RNA confinement, that is, the work required to encapsidate RNA, and thus less efficient packaging. In this paper, we vary the degree of branching as well as the effective Kuhn length and linear charge density of a model RNA, and study their impact on the optimal length of encapsulated genome by capsid proteins. ./cache/cord-006951-tj22dh5o.txt ./txt/cord-006951-tj22dh5o.txt