id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-008588-4eu9v5d3	Chastain, Michael	Structural Elements in RNA	2008-02-29		.txt	text/plain	13667	617	54	The structures of the tRNA anticodon loop and the UUCG loop suggest that the specific loop sequences adopt conformations that are more stable because they contain more hydrogen bonding and stacking interactions-particularly interactions with the sugar-phosphate backbone. Determining the conformation of these loops in RNA is important for understanding how these nucleotides interact with other elements of secondary structure to form tertiary interactions and for understanding how proteins bind to bulge loops. In general, this could occur between any of the secondary structure regions containing unpaired nucleotides (single-stranded regions, hairpin loops, bulge loops, internal loops, and junction loops). There are several examples of RNA molecules containing tertiary contacts between nucleotides that are in loop regions of secondary structure. The high frequency with which known RNA structures contain tertiary pairing between nucleotides that are unpaired in the secondary structure stresses the importance of learning more about such interactions.	./cache/cord-008588-4eu9v5d3.txt	./txt/cord-008588-4eu9v5d3.txt