id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-029779-9b6zs1sb	Casey, Sophie	Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury	2020-07-27		.txt	text/plain	11367	662	52	miR-181a inhibition increased neurite length in vitro in two different types of cell culture-the SH-SY5Y cell line and primary cultures of E14 rat midbrain-and increased expression of BMPR2 in differentiating SH-SY5Ys. Therefore, this miRNA may be a potential therapeutic target with neuroprotective effects. Analyses of previously performed microarray data showed altered expression levels in 70 miRNAs in umbilical cord whole blood in infants with moderate and severe HIE compared with controls and this data have been previously reported by our group [5] . The predicted downstream targets of the six miRNAs were predicted to exert neuroprotective effects, and functional examination of one of the associated pathways-the BMP signalling pathway (a member of the TGFβ superfamily [31] )-in differentiating SH-SY5Y cells revealed inhibition of miR-181a increases expression of the type II receptor BMPR2.	./cache/cord-029779-9b6zs1sb.txt	./txt/cord-029779-9b6zs1sb.txt