id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-103807-x4hrwhkz	Prokop, J. W.	Viral Induced Genetics Revealed by Multi-Dimensional Precision Medicine Transcriptional Workflow	2020-04-06		.txt	text/plain	6843	375	50	Patients often present to the intensive care unit with broad phenotypes, including multiple organ dysfunction syndrome (MODS) resulting from infection, trauma, or other disease processes. Using multi-time point whole blood (cellular/acellular) total transcriptomics in 27 patients, we highlight the promise of simultaneously mapping viral/bacterial load, cell composition, tissue damage biomarkers, balance between syndromic biology vs. The power of RNA generated data likely is in its potential to effect therapeutic changes in individual patients with diverse clinical presentations, such as Multiple Organ Dysfunction Syndrome (MODS). Additional insights from the top mapped bacteria include normal flora elevation of Polynucleobacter necessarius and Bordetella parapertussis in patient 24 suggested to have issues in antigen processing and presentation (case study presented below for RNASEH2B), multiple Streptococcus strains (including pyogenes) identified in patients 11 and 5 that were culture positive, Pandoraea faecigallinarum in patient 10, and Cryobacterium arcticum in patient 10 day 0.	./cache/cord-103807-x4hrwhkz.txt	./txt/cord-103807-x4hrwhkz.txt