id author title date pages extension mime words sentences flesch summary cache txt cord-103823-3rchp9yy Taufer, Michela RNAVLab: A virtual laboratory for studying RNA secondary structures based on grid computing technology 2008-11-30 .txt text/plain 10168 462 50 Despite the computing power of supercomputers, computationally predicting secondary structures with thermodynamic methods is still not feasible when the RNA molecules have long nucleotide sequences and include complex motifs such as pseudoknots. Of course, the scientist who uses such an approach of sampling and rebuilding from segments to predict longer secondary structures has to benefit from the computing capabilities of such a framework without being required to cut and paste results from one code output to another, redirecting or reformatting output files (e.g., from FASTA to EMBL format) before forwarding them to the next step in the analysis, or dealing with distributed computer systems. RNAVLab addresses the challenges above by combining sampling of nucleotide sequences, predictions based on different codes and supported by grid computing technology, and analysis of large sets of secondary structures with different scientific scopes. ./cache/cord-103823-3rchp9yy.txt ./txt/cord-103823-3rchp9yy.txt