id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-104186-fyw1xfgi	Cui, Y	Mof4-1 is an allele of the UPF1/IFS2 gene which affects both mRNA turnover and -1 ribosomal frameshifting efficiency.	1996-10-15		.txt	text/plain	7815	361	58	Cells harboring the above hybrid UPFJ gene had the same three phenotypes as the mof4-1 strain, including: (i) elevated abundance of CYH2 precursor and frameshift reporter LacZ mRNA (Figures 2B and IC); (ii) inability to propagate the M1 killer virus (Table IV, Table IV , #5). A upflA strain (YGC106) containing the lacZ frameshift reporter construct in the zero or -1 frame relative to the translation start site (p315-JD86-ter or p315-JD85-ter) was transformed with a single copy plasmid harboring either the wild-type UPFJ gene, the mof4-1 allele or the vector alone. Thus, the higher expression level of the lacZ gene product in the -1 reading frame in mof4-1 cells as compared Hybrid genes between the wild-type UPFI and the mof4-1 alleles schematically represented in (A) were constructed, transformed into a upflA strain (Y52-) and CYH2 precursor abundance was determined by RNA blotting analysis as described in Figure 1 .	./cache/cord-104186-fyw1xfgi.txt	./txt/cord-104186-fyw1xfgi.txt