id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-263699-gosqpg3k	Martínez, José L.	Role of the Guanine Nucleotide Exchange Factor GBF1 in the Replication of RNA Viruses	2020-06-24		.txt	text/plain	12329	463	42	GBF1 has been shown not only to facilitate the intracellular traffic of different viral and cellular elements during infection, but also to modulate the replication of viral RNA, the formation and maturation of viral replication complexes, and the processing of viral proteins through mechanisms that do not depend on its canonical role in intracellular transport. In addition to the role of GBF1 in the transport of cellular and viral proteins relevant for RNA replication and viral assembly, it has also been observed that this factor can regulate the lipid composition of the membranous web induced by HCV. The role of GBF1 has been found, principally, to depend on its ability to activate distinct Arf proteins, to regulate different transport pathways that permit the communication between the viral replication organelles and cellular organelles (ER and LDs) involved in virus infection.	./cache/cord-263699-gosqpg3k.txt	./txt/cord-263699-gosqpg3k.txt