id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-266921-x9q7dwc4	Worrall, Jonathan AR	Information available at cut rates: structure and mechanism of ribonucleases	2006-12-26		.txt	text/plain	4616	222	49	The exoribonuclease RNase II is representative of an extensive enzyme family found in all three domains of life, whose members play roles in the maturation, turn-Structure and mechanism of ribonucleases Worrall and Luisi 131 Whereas DEAD-box helicases use the free energy of ATP binding and hydrolysis to disrupt secondary structure, RNase R transduces the favourable free energy of RNA backbone hydrolysis into mechanical work that translates the single-stranded substrate further into the catalytic pocket, much like a ratchet. Crystal structures of the core of the exosomes from the archaea Sulfolobus solfataricus and Archaeoglobus fulgidus have recently become available, revealing a hexameric ring comprising two types of RNase-PH-like subunits, known as Rrp41 and Rrp42 (rRNA-processing proteins 41 and 42; see Figure 4a ) [36 ,37 ,38 ] . Structure of Escherichia coli RNase E catalytic domain and its implications for RNA turnover and processing	./cache/cord-266921-x9q7dwc4.txt	./txt/cord-266921-x9q7dwc4.txt