id author title date pages extension mime words sentences flesch summary cache txt cord-280003-ndpuezpo Lou, Bin Serology characteristics of SARS-CoV-2 infection since the exposure and post symptoms onset 2020-03-27 .txt text/plain 3024 190 57 Serial sera of COVID-19 patients were collected and total antibody (Ab), IgM and IgG antibody against SARS-CoV-2 were detected. The first detectible serology marker is total antibody and followed by IgM and IgG, with a median seroconversion time of 15, 18 and 20 day post exposure (d.p.e) or 9, 10 and 12 days post onset, separately. In order to answer some of the questions, we investigated the characteristics of antibody responses in 80 Covid-19 patients during their hospitalization periods, through detecting total antibody, IgM and IgG using immunoassays. A total of 80 Covid-19 patients and 100 to 300 healthy people were tested for antibodies against SARS-CoV-2 using different immunoassays. The present data showed that the sensitivity of total antibody detection was higher than that of IgM and IgG (p<0.001) while the specificities are overall comparable when the same testing technic (ELISA, CLMA or LFIA) is used. ./cache/cord-280003-ndpuezpo.txt ./txt/cord-280003-ndpuezpo.txt