id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-286352-uftl1mx5	Baril, Martin	The Frameshift Stimulatory Signal of Human Immunodeficiency Virus Type 1 Group O is a Pseudoknot	2003-08-15		.txt	text/plain	5666	254	57	Since the region downstream of the stem-loop increases frameshifting in the presence of this stem-loop, as shown in Figure 3 , these results also support our suggestion that the frameshift stimulatory signal in MVP5180 is more complex than a simple stemloop and could correspond to a pseudoknot structure. The frameshift efficiencies of the constructs containing these mutations were assessed in vitro and in cultured cells and are presented in Figure 4 (b) (see also Table 1 To provide an independent support for the pseudoknot structure in subtype MVP5180 of HIV-1 group O frameshift stimulatory signal, we made a structural probing analysis of an RNA fragment encompassing the gag/pol frameshift region of this subtype. Our results show that the frameshift stimulatory signal of subtype MVP5180 of HIV-1 group O is a pseudoknot, where 8 nt of a 10-nt loop capping an 8-bp stem base-pair with a downstream complementary sequence.	./cache/cord-286352-uftl1mx5.txt	./txt/cord-286352-uftl1mx5.txt