id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-290744-m0vpizuh	Kindler, E.	Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response	2016-09-09		.txt	text/plain	7229	399	52	Here, we will summarize the insights gathered so far on an important aspect of virulence and host adaptation, the interactions of SARS-CoV and MERS-CoV with antiviral interferon (IFN) responses of human cells. The broad antiviral activity of IFNs occurs on several levels, namely virus entry, viral polymerase function, host cell translation, RNA availability, RNA stability, particle budding, apoptosis, or general boosting of innate and adaptive immune responses. Crystal structure of the middle east respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells Middle East respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response	./cache/cord-290744-m0vpizuh.txt	./txt/cord-290744-m0vpizuh.txt