id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-306754-qohrnpgq	Lee, Justin S.	Targeted Enrichment for Pathogen Detection and Characterization in Three Felid Species	2017-05-23		.txt	text/plain	7158	335	48	Our report provides advances in investigating several important aspects of TGC assay design, including (i) the range of fold enrichment possible for targeted nucleic acids, (ii) comparison of TGC pathogen detection with traditional methods currently used by diagnostic laboratories, (iii) documentation that a single assay design can be applied to more than one host species, (iv) the applicability of TGC to characterize pathogens in the context of veterinary medicine, and (v) the ability of TGC-NGS to characterize intrahost genetic diversity of viral pathogens (4) (5) (6) . Mean enrichment values of 250,000-fold and 9,100,000-fold with the DNA and RNA probes, respectively, and 147,000-fold for FIV contained in tissues clearly demonstrate the ability of the targeted capture probes to dramatically alter the relative abundance of specific nucleic acids across a range of sample types and diverse pathogen taxa.	./cache/cord-306754-qohrnpgq.txt	./txt/cord-306754-qohrnpgq.txt