id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324640-2zhaknbi	Munday, Diane C.	Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus	2010-07-20		.txt	text/plain	12318	588	39	Although RNA synthesis and virus assembly occur in the cytoplasm, HRSV is known to induce nuclear responses in the host cell as replication alters global gene expression. More recently, 2DE was used to compare the potential effect of several different negative strand RNA viruses, including HRSV, parainfluenza virus, human metap-neumovirus, measles virus, and influenza virus, on the host cell proteome with common changes in proteins involved with apoptosis and endoplasmic reticulum stress being highlighted (27) . Together, the indirect immunofluorescence confocal microscopy images supported the observations from the quantitative proteomic analysis that the abundance of mitochondrial proteins (particularly pore proteins) was altered in HRSV-infected cells. Potential Disruption of Proteins Involved in Nucleocytoplasmic Trafficking-Network pathway analysis indicated that the abundance of nuclear pore complex components and proteins involved in the nucleocytoplasmic trafficking of proteins and RNA differed between HRSV-infected and mock-infected cells (Fig. 4) .	./cache/cord-324640-2zhaknbi.txt	./txt/cord-324640-2zhaknbi.txt