id author title date pages extension mime words sentences flesch summary cache txt cord-335864-392xmrq0 Sun, Yu-Meng Principles and innovative technologies for decrypting noncoding RNAs: from discovery and functional prediction to clinical application 2020-08-10 .txt text/plain 13942 786 45 With recent developments in sequencing methods and information analysis, an increasing number of novel ncRNAs have been identified, including long noncoding RNAs (lncRNAs) [5, 6] , circular RNAs (circRNAs) [7, 8] , and novel small ncRNAs [9] [10] [11] . Most circRNAs derived from mRNA back-splicing lose translational capacity because of the lack of effective ORFs or ribosome entry approaches, while a few circRNAs from coding or Sno-lncRNAs maintain their stability by their classical stem-loop structures of snoRNAs. c Alternative splicing within circRNAs. d A number of novel small ncRNAs derived from rRNAs (rRFs), tRNAs (tsRNAs), and snoRNAs (sdRNAs) have also been found to be enriched in RNA-induced silencing complexes (RISCs) and function in a miRNA-like pathway This approach can provide in-depth analysis of transcripts from target regions of genome. ./cache/cord-335864-392xmrq0.txt ./txt/cord-335864-392xmrq0.txt