id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-350342-j4p8235a	Brocato, Rebecca L.	Disruption of Adaptive Immunity Enhances Disease in SARS-CoV-2-Infected Syrian Hamsters	2020-10-27		.txt	text/plain	5265	283	49	All of the SARS-CoV-2-challenged hamsters had detectable viral RNA in pharyngeal swabs at the first time point assayed, 3 dpi, and remained consistent (10 3 to 10 5 molecules of nucleocapsid using a second primer set [N2] per 100 ng RNA) throughout the duration of CyP treatment (Fig. 1C) . Viral RNA and infectious virus were detected in lung tissue from a subset of hamsters collected 13 dpi, on the day of euthanasia of moribund animals (14 to 34 dpi), or after euthanasia at 35 dpi (end of study) ( Fig. 1E and F). Electron microscopy studies were performed on lung sections of SARS-CoV-2infected, CyP-treated hamsters with various lung viral loads (Fig. 1) . Similarly, lung tissue collected at 13 dpi (end of study) indicate comparable levels of viral RNA detected (Fig. 6D ) but significantly reduced infectious virus in Centi-F1 MAb-treated animals (P ϭ 0.0002; unpaired t test) (Fig. 6E) .	./cache/cord-350342-j4p8235a.txt	./txt/cord-350342-j4p8235a.txt