id author title date pages extension mime words sentences flesch summary cache txt cord-350697-u032yk0z Roy, Anupam Can concomitant use of zinc and curcumin with other immunity‐boosting nutraceuticals be the arsenal against COVID‐19? 2020-06-02 .txt text/plain 1110 68 44 Lack of effective prophylaxis against COVID-19 has prompted regulatory authorities to propose boosting of immunity of individuals via nutritional supplements. While modern medicine directly confronts an antigen (via vaccination or antibiotic), in comparison nutraceuticals, food supplements, and traditional medicines activate the overall immunity of the human body. Both molecules have a proven history of antiviral activity in both in vitro and in vivo trials thus could be leadings in developing new prophylactic candidates against COVID-19. Thus, these supplements as a part of the food, nutraceutical, or traditional medicines may pave the way towards developing a therapeutic strategy against the COVID-19 pandemic. The success story of TCM is continuously inspiring us to test food supplements and raise individual immunity. Potential mechanisms by which Curcumin and Zinc can exert therapeutic effects against COVID-19. Curcumin inhibits SARS-CoV-2 entry by binding directly to the receptorbinding domain (RBD) of Spike (S) protein of the virus. ./cache/cord-350697-u032yk0z.txt ./txt/cord-350697-u032yk0z.txt