id	sid	tid	token	lemma	pos
cord-327272-fspxett8	1	1	key	key	JJ
cord-327272-fspxett8	1	2	:	:	:
cord-327272-fspxett8	1	3	cord-327272-fspxett8	cord-327272-fspxett8	NN
cord-327272-fspxett8	1	4	authors	author	NNS
cord-327272-fspxett8	1	5	:	:	:
cord-327272-fspxett8	1	6	Buonaguro	Buonaguro	NNP
cord-327272-fspxett8	1	7	,	,	,
cord-327272-fspxett8	1	8	Luigi	Luigi	NNP
cord-327272-fspxett8	1	9	;	;	:
cord-327272-fspxett8	1	10	Buonaguro	Buonaguro	NNP
cord-327272-fspxett8	1	11	,	,	,
cord-327272-fspxett8	1	12	Franco	Franco	NNP
cord-327272-fspxett8	1	13	M.	M.	NNP
cord-327272-fspxett8	2	1	title	title	NN
cord-327272-fspxett8	2	2	:	:	:
cord-327272-fspxett8	2	3	Knowledge	knowledge	NN
cord-327272-fspxett8	2	4	-	-	HYPH
cord-327272-fspxett8	2	5	based	base	VBN
cord-327272-fspxett8	2	6	repositioning	repositioning	NN
cord-327272-fspxett8	2	7	of	of	IN
cord-327272-fspxett8	2	8	the	the	DT
cord-327272-fspxett8	2	9	anti	anti	JJ
cord-327272-fspxett8	2	10	-	-	JJ
cord-327272-fspxett8	2	11	HCV	hcv	JJ
cord-327272-fspxett8	2	12	direct	direct	JJ
cord-327272-fspxett8	2	13	antiviral	antiviral	JJ
cord-327272-fspxett8	2	14	agent	agent	NN
cord-327272-fspxett8	2	15	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	2	16	as	as	IN
cord-327272-fspxett8	2	17	SARS	SARS	NNP
cord-327272-fspxett8	2	18	-	-	HYPH
cord-327272-fspxett8	2	19	CoV-2	CoV-2	NNP
cord-327272-fspxett8	2	20	treatment	treatment	NN
cord-327272-fspxett8	2	21	date	date	NN
cord-327272-fspxett8	2	22	:	:	:
cord-327272-fspxett8	2	23	2020	2020	CD
cord-327272-fspxett8	2	24	-	-	HYPH
cord-327272-fspxett8	2	25	05	05	CD
cord-327272-fspxett8	2	26	-	-	HYPH
cord-327272-fspxett8	2	27	12	12	CD
cord-327272-fspxett8	2	28	journal	journal	NN
cord-327272-fspxett8	2	29	:	:	:
cord-327272-fspxett8	3	1	Infect	infect	VB
cord-327272-fspxett8	3	2	Agent	Agent	NNP
cord-327272-fspxett8	3	3	Cancer	Cancer	NNP
cord-327272-fspxett8	3	4	DOI	DOI	NNP
cord-327272-fspxett8	3	5	:	:	:
cord-327272-fspxett8	4	1	10.1186	10.1186	CD
cord-327272-fspxett8	4	2	/	/	SYM
cord-327272-fspxett8	4	3	s13027	s13027	JJ
cord-327272-fspxett8	4	4	-	-	HYPH
cord-327272-fspxett8	4	5	020	020	CD
cord-327272-fspxett8	4	6	-	-	HYPH
cord-327272-fspxett8	4	7	00302-x	00302-x	ADD
cord-327272-fspxett8	5	1	sha	sha	NNP
cord-327272-fspxett8	5	2	:	:	:
cord-327272-fspxett8	5	3	d8353f529f7ddc3b27675b5ffc8d1fde4325a9cc	d8353f529f7ddc3b27675b5ffc8d1fde4325a9cc	CD
cord-327272-fspxett8	5	4	doc_id	doc_id	CD
cord-327272-fspxett8	5	5	:	:	:
cord-327272-fspxett8	5	6	327272	327272	CD
cord-327272-fspxett8	5	7	cord_uid	cord_uid	NNS
cord-327272-fspxett8	5	8	:	:	:
cord-327272-fspxett8	6	1	fspxett8	fspxett8	NNP
cord-327272-fspxett8	7	1	The	the	DT
cord-327272-fspxett8	7	2	new	new	JJ
cord-327272-fspxett8	7	3	human	human	JJ
cord-327272-fspxett8	7	4	coronavirus	coronavirus	NN
cord-327272-fspxett8	7	5	named	name	VBN
cord-327272-fspxett8	7	6	SARS	SARS	NNP
cord-327272-fspxett8	7	7	-	-	HYPH
cord-327272-fspxett8	7	8	CoV-2	CoV-2	NNP
cord-327272-fspxett8	7	9	is	be	VBZ
cord-327272-fspxett8	7	10	a	a	DT
cord-327272-fspxett8	7	11	positive	positive	JJ
cord-327272-fspxett8	7	12	-	-	HYPH
cord-327272-fspxett8	7	13	sense	sense	NN
cord-327272-fspxett8	7	14	RNA	RNA	NNP
cord-327272-fspxett8	7	15	virus	virus	NN
cord-327272-fspxett8	7	16	for	for	IN
cord-327272-fspxett8	7	17	which	which	WDT
cord-327272-fspxett8	7	18	no	no	DT
cord-327272-fspxett8	7	19	specific	specific	JJ
cord-327272-fspxett8	7	20	drugs	drug	NNS
cord-327272-fspxett8	7	21	are	be	VBP
cord-327272-fspxett8	7	22	currently	currently	RB
cord-327272-fspxett8	7	23	available	available	JJ
cord-327272-fspxett8	7	24	.	.	.
cord-327272-fspxett8	8	1	A	a	DT
cord-327272-fspxett8	8	2	knowledge	knowledge	NN
cord-327272-fspxett8	8	3	-	-	HYPH
cord-327272-fspxett8	8	4	based	base	VBN
cord-327272-fspxett8	8	5	analysis	analysis	NN
cord-327272-fspxett8	8	6	strongly	strongly	RB
cord-327272-fspxett8	8	7	suggests	suggest	VBZ
cord-327272-fspxett8	8	8	a	a	DT
cord-327272-fspxett8	8	9	possible	possible	JJ
cord-327272-fspxett8	8	10	repositioning	repositioning	NN
cord-327272-fspxett8	8	11	of	of	IN
cord-327272-fspxett8	8	12	the	the	DT
cord-327272-fspxett8	8	13	anti	anti	JJ
cord-327272-fspxett8	8	14	-	-	JJ
cord-327272-fspxett8	8	15	HCV	hcv	JJ
cord-327272-fspxett8	8	16	direct	direct	JJ
cord-327272-fspxett8	8	17	antiviral	antiviral	JJ
cord-327272-fspxett8	8	18	agent	agent	NN
cord-327272-fspxett8	8	19	(	(	-LRB-
cord-327272-fspxett8	8	20	DAA	DAA	NNP
cord-327272-fspxett8	8	21	)	)	-RRB-
cord-327272-fspxett8	8	22	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	8	23	as	as	IN
cord-327272-fspxett8	8	24	treatment	treatment	NN
cord-327272-fspxett8	8	25	for	for	IN
cord-327272-fspxett8	8	26	SARS	SARS	NNP
cord-327272-fspxett8	8	27	-	-	HYPH
cord-327272-fspxett8	8	28	CoV-2	CoV-2	NNP
cord-327272-fspxett8	8	29	.	.	.
cord-327272-fspxett8	9	1	Indeed	indeed	RB
cord-327272-fspxett8	9	2	,	,	,
cord-327272-fspxett8	9	3	the	the	DT
cord-327272-fspxett8	9	4	RNA	RNA	NNP
cord-327272-fspxett8	9	5	-	-	HYPH
cord-327272-fspxett8	9	6	dependent	dependent	JJ
cord-327272-fspxett8	9	7	RNA	RNA	NNP
cord-327272-fspxett8	9	8	-	-	,
cord-327272-fspxett8	9	9	polymerases	polymerase	NNS
cord-327272-fspxett8	9	10	(	(	-LRB-
cord-327272-fspxett8	9	11	RdRp	RdRp	NNP
cord-327272-fspxett8	9	12	)	)	-RRB-
cord-327272-fspxett8	9	13	of	of	IN
cord-327272-fspxett8	9	14	the	the	DT
cord-327272-fspxett8	9	15	two	two	CD
cord-327272-fspxett8	9	16	viruses	virus	NNS
cord-327272-fspxett8	9	17	show	show	VBP
cord-327272-fspxett8	9	18	high	high	JJ
cord-327272-fspxett8	9	19	sequence	sequence	NN
cord-327272-fspxett8	9	20	and	and	CC
cord-327272-fspxett8	9	21	structural	structural	JJ
cord-327272-fspxett8	9	22	homology	homology	NN
cord-327272-fspxett8	9	23	,	,	,
cord-327272-fspxett8	9	24	supporting	support	VBG
cord-327272-fspxett8	9	25	the	the	DT
cord-327272-fspxett8	9	26	likelihood	likelihood	NN
cord-327272-fspxett8	9	27	of	of	IN
cord-327272-fspxett8	9	28	binding	bind	VBG
cord-327272-fspxett8	9	29	the	the	DT
cord-327272-fspxett8	9	30	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	9	31	molecule	molecule	NN
cord-327272-fspxett8	9	32	with	with	IN
cord-327272-fspxett8	9	33	similar	similar	JJ
cord-327272-fspxett8	9	34	efficiency	efficiency	NN
cord-327272-fspxett8	9	35	.	.	.
cord-327272-fspxett8	10	1	Such	such	PDT
cord-327272-fspxett8	10	2	a	a	DT
cord-327272-fspxett8	10	3	repositioning	repositioning	NN
cord-327272-fspxett8	10	4	would	would	MD
cord-327272-fspxett8	10	5	allow	allow	VB
cord-327272-fspxett8	10	6	the	the	DT
cord-327272-fspxett8	10	7	containment	containment	NN
cord-327272-fspxett8	10	8	of	of	IN
cord-327272-fspxett8	10	9	the	the	DT
cord-327272-fspxett8	10	10	SARS	SARS	NNP
cord-327272-fspxett8	10	11	-	-	HYPH
cord-327272-fspxett8	10	12	CoV-2	CoV-2	NNP
cord-327272-fspxett8	10	13	pandemic	pandemic	NN
cord-327272-fspxett8	10	14	and	and	CC
cord-327272-fspxett8	10	15	limit	limit	VB
cord-327272-fspxett8	10	16	the	the	DT
cord-327272-fspxett8	10	17	progression	progression	NN
cord-327272-fspxett8	10	18	of	of	IN
cord-327272-fspxett8	10	19	disease	disease	NN
cord-327272-fspxett8	10	20	to	to	IN
cord-327272-fspxett8	10	21	potentially	potentially	RB
cord-327272-fspxett8	10	22	deadly	deadly	JJ
cord-327272-fspxett8	10	23	COVID19	covid19	NN
cord-327272-fspxett8	10	24	.	.	.
cord-327272-fspxett8	11	1	A	a	DT
cord-327272-fspxett8	11	2	new	new	JJ
cord-327272-fspxett8	11	3	human	human	JJ
cord-327272-fspxett8	11	4	coronavirus	coronavirus	NN
cord-327272-fspxett8	11	5	named	name	VBN
cord-327272-fspxett8	11	6	SARS	SARS	NNP
cord-327272-fspxett8	11	7	-	-	HYPH
cord-327272-fspxett8	11	8	CoV-2	CoV-2	NNP
cord-327272-fspxett8	11	9	was	be	VBD
cord-327272-fspxett8	11	10	identified	identify	VBN
cord-327272-fspxett8	11	11	in	in	IN
cord-327272-fspxett8	11	12	several	several	JJ
cord-327272-fspxett8	11	13	cases	case	NNS
cord-327272-fspxett8	11	14	of	of	IN
cord-327272-fspxett8	11	15	acute	acute	JJ
cord-327272-fspxett8	11	16	respiratory	respiratory	JJ
cord-327272-fspxett8	11	17	syndrome	syndrome	NN
cord-327272-fspxett8	11	18	in	in	IN
cord-327272-fspxett8	11	19	Wuhan	Wuhan	NNP
cord-327272-fspxett8	11	20	,	,	,
cord-327272-fspxett8	11	21	China	China	NNP
cord-327272-fspxett8	11	22	in	in	IN
cord-327272-fspxett8	11	23	December	December	NNP
cord-327272-fspxett8	11	24	2019	2019	CD
cord-327272-fspxett8	11	25	[	[	-LRB-
cord-327272-fspxett8	11	26	1	1	CD
cord-327272-fspxett8	11	27	,	,	,
cord-327272-fspxett8	11	28	2	2	CD
cord-327272-fspxett8	11	29	]	]	-RRB-
cord-327272-fspxett8	11	30	.	.	.
cord-327272-fspxett8	12	1	The	the	DT
cord-327272-fspxett8	12	2	transmission	transmission	NN
cord-327272-fspxett8	12	3	pathways	pathway	NNS
cord-327272-fspxett8	12	4	of	of	IN
cord-327272-fspxett8	12	5	the	the	DT
cord-327272-fspxett8	12	6	new	new	JJ
cord-327272-fspxett8	12	7	coronavirus	coronavirus	NN
cord-327272-fspxett8	12	8	include	include	VBP
cord-327272-fspxett8	12	9	direct	direct	JJ
cord-327272-fspxett8	12	10	transmission	transmission	NN
cord-327272-fspxett8	12	11	(	(	-LRB-
cord-327272-fspxett8	12	12	coughing	cough	VBG
cord-327272-fspxett8	12	13	,	,	,
cord-327272-fspxett8	12	14	sneezing	sneezing	NN
cord-327272-fspxett8	12	15	and	and	CC
cord-327272-fspxett8	12	16	inhalation	inhalation	NN
cord-327272-fspxett8	12	17	transmission	transmission	NN
cord-327272-fspxett8	12	18	of	of	IN
cord-327272-fspxett8	12	19	droplets	droplet	NNS
cord-327272-fspxett8	12	20	)	)	-RRB-
cord-327272-fspxett8	12	21	and	and	CC
cord-327272-fspxett8	12	22	transmission	transmission	NN
cord-327272-fspxett8	12	23	by	by	IN
cord-327272-fspxett8	12	24	contact	contact	NN
cord-327272-fspxett8	12	25	with	with	IN
cord-327272-fspxett8	12	26	mucosa	mucosa	JJ
cord-327272-fspxett8	12	27	[	[	-LRB-
cord-327272-fspxett8	12	28	3	3	CD
cord-327272-fspxett8	12	29	]	]	-RRB-
cord-327272-fspxett8	12	30	.	.	.
cord-327272-fspxett8	13	1	The	the	DT
cord-327272-fspxett8	13	2	viral	viral	JJ
cord-327272-fspxett8	13	3	load	load	NN
cord-327272-fspxett8	13	4	of	of	IN
cord-327272-fspxett8	13	5	SARS	SARS	NNP
cord-327272-fspxett8	13	6	-	-	HYPH
cord-327272-fspxett8	13	7	CoV-2	CoV-2	NNP
cord-327272-fspxett8	13	8	in	in	IN
cord-327272-fspxett8	13	9	saliva	saliva	NN
cord-327272-fspxett8	13	10	can	can	MD
cord-327272-fspxett8	13	11	exceed	exceed	VB
cord-327272-fspxett8	13	12	1	1	CD
cord-327272-fspxett8	13	13	×	×	NN
cord-327272-fspxett8	13	14	10	10	CD
cord-327272-fspxett8	13	15	8	8	CD
cord-327272-fspxett8	13	16	viral	viral	JJ
cord-327272-fspxett8	13	17	copies	copy	NNS
cord-327272-fspxett8	13	18	per	per	IN
cord-327272-fspxett8	13	19	milliliter	milliliter	NN
cord-327272-fspxett8	13	20	[	[	-LRB-
cord-327272-fspxett8	13	21	4	4	CD
cord-327272-fspxett8	13	22	]	]	-RRB-
cord-327272-fspxett8	13	23	both	both	CC
cord-327272-fspxett8	13	24	in	in	IN
cord-327272-fspxett8	13	25	symptomatic	symptomatic	JJ
cord-327272-fspxett8	13	26	and	and	CC
cord-327272-fspxett8	13	27	asymptomatic	asymptomatic	JJ
cord-327272-fspxett8	13	28	positive	positive	JJ
cord-327272-fspxett8	13	29	subjects	subject	NNS
cord-327272-fspxett8	13	30	[	[	-LRB-
cord-327272-fspxett8	13	31	5	5	CD
cord-327272-fspxett8	13	32	]	]	-RRB-
cord-327272-fspxett8	13	33	.	.	.
cord-327272-fspxett8	14	1	Consequently	consequently	RB
cord-327272-fspxett8	14	2	,	,	,
cord-327272-fspxett8	14	3	it	-PRON-	PRP
cord-327272-fspxett8	14	4	is	be	VBZ
cord-327272-fspxett8	14	5	necessary	necessary	JJ
cord-327272-fspxett8	14	6	to	to	TO
cord-327272-fspxett8	14	7	reduce	reduce	VB
cord-327272-fspxett8	14	8	or	or	CC
cord-327272-fspxett8	14	9	block	block	VB
cord-327272-fspxett8	14	10	viral	viral	JJ
cord-327272-fspxett8	14	11	replication	replication	NN
cord-327272-fspxett8	14	12	to	to	TO
cord-327272-fspxett8	14	13	avoid	avoid	VB
cord-327272-fspxett8	14	14	the	the	DT
cord-327272-fspxett8	14	15	progression	progression	NN
cord-327272-fspxett8	14	16	of	of	IN
cord-327272-fspxett8	14	17	the	the	DT
cord-327272-fspxett8	14	18	disease	disease	NN
cord-327272-fspxett8	14	19	towards	towards	IN
cord-327272-fspxett8	14	20	the	the	DT
cord-327272-fspxett8	14	21	full	full	RB
cord-327272-fspxett8	14	22	-	-	HYPH
cord-327272-fspxett8	14	23	blown	blown	JJ
cord-327272-fspxett8	14	24	and	and	CC
cord-327272-fspxett8	14	25	potentially	potentially	RB
cord-327272-fspxett8	14	26	lethal	lethal	JJ
cord-327272-fspxett8	14	27	form	form	NN
cord-327272-fspxett8	14	28	(	(	-LRB-
cord-327272-fspxett8	14	29	COVID19	covid19	NN
cord-327272-fspxett8	14	30	)	)	-RRB-
cord-327272-fspxett8	14	31	,	,	,
cord-327272-fspxett8	14	32	but	but	CC
cord-327272-fspxett8	14	33	also	also	RB
cord-327272-fspxett8	14	34	to	to	TO
cord-327272-fspxett8	14	35	reduce	reduce	VB
cord-327272-fspxett8	14	36	the	the	DT
cord-327272-fspxett8	14	37	viral	viral	JJ
cord-327272-fspxett8	14	38	titer	titer	NN
cord-327272-fspxett8	14	39	and	and	CC
cord-327272-fspxett8	14	40	viral	viral	JJ
cord-327272-fspxett8	14	41	shedding	shed	VBG
cord-327272-fspxett8	14	42	through	through	IN
cord-327272-fspxett8	14	43	saliva	saliva	NN
cord-327272-fspxett8	14	44	,	,	,
cord-327272-fspxett8	14	45	in	in	IN
cord-327272-fspxett8	14	46	symptomatic	symptomatic	JJ
cord-327272-fspxett8	14	47	and	and	CC
cord-327272-fspxett8	14	48	asymptomatic	asymptomatic	JJ
cord-327272-fspxett8	14	49	infected	infected	JJ
cord-327272-fspxett8	14	50	individuals	individual	NNS
cord-327272-fspxett8	14	51	.	.	.
cord-327272-fspxett8	15	1	Specific	specific	JJ
cord-327272-fspxett8	15	2	drugs	drug	NNS
cord-327272-fspxett8	15	3	for	for	IN
cord-327272-fspxett8	15	4	SARS	SARS	NNP
cord-327272-fspxett8	15	5	-	-	HYPH
cord-327272-fspxett8	15	6	CoV-2	CoV-2	NNP
cord-327272-fspxett8	15	7	are	be	VBP
cord-327272-fspxett8	15	8	obviously	obviously	RB
cord-327272-fspxett8	15	9	not	not	RB
cord-327272-fspxett8	15	10	available	available	JJ
cord-327272-fspxett8	15	11	.	.	.
cord-327272-fspxett8	16	1	Currently	currently	RB
cord-327272-fspxett8	16	2	,	,	,
cord-327272-fspxett8	16	3	drugs	drug	NNS
cord-327272-fspxett8	16	4	originally	originally	RB
cord-327272-fspxett8	16	5	developed	develop	VBN
cord-327272-fspxett8	16	6	for	for	IN
cord-327272-fspxett8	16	7	HIV	HIV	NNP
cord-327272-fspxett8	16	8	(	(	-LRB-
cord-327272-fspxett8	16	9	e.g.	e.g.	IN
cord-327272-fspxett8	16	10	lopinavir	lopinavir	NNP
cord-327272-fspxett8	16	11	,	,	,
cord-327272-fspxett8	16	12	ritonavir	ritonavir	NNP
cord-327272-fspxett8	16	13	)	)	-RRB-
cord-327272-fspxett8	16	14	are	be	VBP
cord-327272-fspxett8	16	15	under	under	IN
cord-327272-fspxett8	16	16	evaluation	evaluation	NN
cord-327272-fspxett8	16	17	on	on	IN
cord-327272-fspxett8	16	18	the	the	DT
cord-327272-fspxett8	16	19	basis	basis	NN
cord-327272-fspxett8	16	20	of	of	IN
cord-327272-fspxett8	16	21	weak	weak	JJ
cord-327272-fspxett8	16	22	evidences	evidence	NNS
cord-327272-fspxett8	16	23	from	from	IN
cord-327272-fspxett8	16	24	retrospective	retrospective	JJ
cord-327272-fspxett8	16	25	analyses	analysis	NNS
cord-327272-fspxett8	16	26	suggesting	suggest	VBG
cord-327272-fspxett8	16	27	clinical	clinical	JJ
cord-327272-fspxett8	16	28	benefit	benefit	NN
cord-327272-fspxett8	16	29	in	in	IN
cord-327272-fspxett8	16	30	the	the	DT
cord-327272-fspxett8	16	31	treatment	treatment	NN
cord-327272-fspxett8	16	32	of	of	IN
cord-327272-fspxett8	16	33	the	the	DT
cord-327272-fspxett8	16	34	two	two	CD
cord-327272-fspxett8	16	35	previous	previous	JJ
cord-327272-fspxett8	16	36	coronavirus	coronavirus	NN
cord-327272-fspxett8	16	37	epidemics	epidemic	NNS
cord-327272-fspxett8	16	38	[	[	-LRB-
cord-327272-fspxett8	16	39	6	6	CD
cord-327272-fspxett8	16	40	]	]	-RRB-
cord-327272-fspxett8	16	41	.	.	.
cord-327272-fspxett8	17	1	Similarly	similarly	RB
cord-327272-fspxett8	17	2	,	,	,
cord-327272-fspxett8	17	3	anti	anti	JJ
cord-327272-fspxett8	17	4	-	-	JJ
cord-327272-fspxett8	17	5	malaria	malaria	JJ
cord-327272-fspxett8	17	6	chloroquine	chloroquine	NN
cord-327272-fspxett8	17	7	or	or	CC
cord-327272-fspxett8	17	8	hydroxychloroquine	hydroxychloroquine	NN
cord-327272-fspxett8	17	9	are	be	VBP
cord-327272-fspxett8	17	10	tested	test	VBN
cord-327272-fspxett8	17	11	[	[	-LRB-
cord-327272-fspxett8	17	12	7	7	CD
cord-327272-fspxett8	17	13	]	]	-RRB-
cord-327272-fspxett8	17	14	.	.	.
cord-327272-fspxett8	18	1	The	the	DT
cord-327272-fspxett8	18	2	inhibitor	inhibitor	NN
cord-327272-fspxett8	18	3	of	of	IN
cord-327272-fspxett8	18	4	Influenza	Influenza	NNP
cord-327272-fspxett8	18	5	's	's	POS
cord-327272-fspxett8	18	6	polymerase	polymerase	NN
cord-327272-fspxett8	18	7	Favipiravir	Favipiravir	NNP
cord-327272-fspxett8	18	8	is	be	VBZ
cord-327272-fspxett8	18	9	currently	currently	RB
cord-327272-fspxett8	18	10	evaluated	evaluate	VBN
cord-327272-fspxett8	18	11	in	in	IN
cord-327272-fspxett8	18	12	a	a	DT
cord-327272-fspxett8	18	13	clinical	clinical	JJ
cord-327272-fspxett8	18	14	trial	trial	NN
cord-327272-fspxett8	18	15	in	in	IN
cord-327272-fspxett8	18	16	combination	combination	NN
cord-327272-fspxett8	18	17	with	with	IN
cord-327272-fspxett8	18	18	anti	anti	JJ
cord-327272-fspxett8	18	19	-	-	JJ
cord-327272-fspxett8	18	20	IL-6	il-6	JJ
cord-327272-fspxett8	18	21	receptor	receptor	NN
cord-327272-fspxett8	18	22	Tocilizumab	Tocilizumab	NNP
cord-327272-fspxett8	18	23	(	(	-LRB-
cord-327272-fspxett8	18	24	NCT04310228	NCT04310228	NNP
cord-327272-fspxett8	18	25	)	)	-RRB-
cord-327272-fspxett8	18	26	.	.	.
cord-327272-fspxett8	19	1	Finally	finally	RB
cord-327272-fspxett8	19	2	,	,	,
cord-327272-fspxett8	19	3	the	the	DT
cord-327272-fspxett8	19	4	inhibitor	inhibitor	NN
cord-327272-fspxett8	19	5	of	of	IN
cord-327272-fspxett8	19	6	Ebolavirus	Ebolavirus	NNP
cord-327272-fspxett8	19	7	'	'	POS
cord-327272-fspxett8	19	8	polymerase	polymerase	NN
cord-327272-fspxett8	19	9	Remdesivir	Remdesivir	NNP
cord-327272-fspxett8	19	10	is	be	VBZ
cord-327272-fspxett8	19	11	currently	currently	RB
cord-327272-fspxett8	19	12	evaluated	evaluate	VBN
cord-327272-fspxett8	19	13	in	in	IN
cord-327272-fspxett8	19	14	two	two	CD
cord-327272-fspxett8	19	15	major	major	JJ
cord-327272-fspxett8	19	16	SIMPLE	simple	JJ
cord-327272-fspxett8	19	17	clinical	clinical	JJ
cord-327272-fspxett8	19	18	trials	trial	NNS
cord-327272-fspxett8	19	19	(	(	-LRB-
cord-327272-fspxett8	19	20	NCT04292899	NCT04292899	NNP
cord-327272-fspxett8	19	21	;	;	:
cord-327272-fspxett8	19	22	NCT04257656	NCT04257656	NNP
cord-327272-fspxett8	19	23	)	)	-RRB-
cord-327272-fspxett8	19	24	[	[	-LRB-
cord-327272-fspxett8	19	25	8	8	CD
cord-327272-fspxett8	19	26	]	]	-RRB-
cord-327272-fspxett8	19	27	.	.	.
cord-327272-fspxett8	20	1	On	on	IN
cord-327272-fspxett8	20	2	Apr.	April	NNP
cord-327272-fspxett8	20	3	29	29	CD
cord-327272-fspxett8	20	4	,	,	,
cord-327272-fspxett8	20	5	2020	2020	CD
cord-327272-fspxett8	20	6	it	-PRON-	PRP
cord-327272-fspxett8	20	7	was	be	VBD
cord-327272-fspxett8	20	8	announced	announce	VBN
cord-327272-fspxett8	20	9	that	that	IN
cord-327272-fspxett8	20	10	results	result	NNS
cord-327272-fspxett8	20	11	from	from	IN
cord-327272-fspxett8	20	12	the	the	DT
cord-327272-fspxett8	20	13	trial	trial	NN
cord-327272-fspxett8	20	14	NCT04292899	NCT04292899	NNP
cord-327272-fspxett8	20	15	showed	show	VBD
cord-327272-fspxett8	20	16	clinical	clinical	JJ
cord-327272-fspxett8	20	17	improvement	improvement	NN
cord-327272-fspxett8	20	18	for	for	IN
cord-327272-fspxett8	20	19	50	50	CD
cord-327272-fspxett8	20	20	percent	percent	NN
cord-327272-fspxett8	20	21	of	of	IN
cord-327272-fspxett8	20	22	patients	patient	NNS
cord-327272-fspxett8	20	23	in	in	IN
cord-327272-fspxett8	20	24	10	10	CD
cord-327272-fspxett8	20	25	days	day	NNS
cord-327272-fspxett8	20	26	in	in	IN
cord-327272-fspxett8	20	27	the	the	DT
cord-327272-fspxett8	20	28	5-day	5-day	JJ
cord-327272-fspxett8	20	29	treatment	treatment	NN
cord-327272-fspxett8	20	30	group	group	NN
cord-327272-fspxett8	20	31	and	and	CC
cord-327272-fspxett8	20	32	11	11	CD
cord-327272-fspxett8	20	33	days	day	NNS
cord-327272-fspxett8	20	34	in	in	IN
cord-327272-fspxett8	20	35	the	the	DT
cord-327272-fspxett8	20	36	10-day	10-day	CD
cord-327272-fspxett8	20	37	treatment	treatment	NN
cord-327272-fspxett8	20	38	group	group	NN
cord-327272-fspxett8	20	39	(	(	-LRB-
cord-327272-fspxett8	20	40	https://www	https://www	.
cord-327272-fspxett8	20	41	.	.	.
cord-327272-fspxett8	21	1	gilead.com/news-and-press/press-room/press-releases/202	gilead.com/news-and-press/press-room/press-releases/202	NNP
cord-327272-fspxett8	21	2	0/4	0/4	CD
cord-327272-fspxett8	22	1	/gilead	/gilead	,
cord-327272-fspxett8	22	2	-	-	:
cord-327272-fspxett8	22	3	announces	announce	VBZ
cord-327272-fspxett8	22	4	-	-	HYPH
cord-327272-fspxett8	22	5	results	result	NNS
cord-327272-fspxett8	22	6	-	-	HYPH
cord-327272-fspxett8	22	7	from	from	IN
cord-327272-fspxett8	22	8	-	-	HYPH
cord-327272-fspxett8	22	9	phase-3-trial	phase-3-trial	NN
cord-327272-fspxett8	22	10	-	-	HYPH
cord-327272-fspxett8	22	11	of	of	IN
cord-327272-fspxett8	22	12	-	-	HYPH
cord-327272-fspxett8	22	13	investigational	investigational	JJ
cord-327272-fspxett8	22	14	-	-	HYPH
cord-327272-fspxett8	22	15	antiviral	antiviral	JJ
cord-327272-fspxett8	22	16	-	-	HYPH
cord-327272-fspxett8	22	17	remdesivir	remdesivir	NN
cord-327272-fspxett8	22	18	-	-	HYPH
cord-327272-fspxett8	22	19	in	in	IN
cord-327272-fspxett8	22	20	-	-	HYPH
cord-327272-fspxett8	22	21	patients	patient	NNS
cord-327272-fspxett8	22	22	-	-	HYPH
cord-327272-fspxett8	22	23	with	with	IN
cord-327272-fspxett8	22	24	-	-	HYPH
cord-327272-fspxett8	22	25	severecovid-19	severecovid-19	NN
cord-327272-fspxett8	22	26	)	)	-RRB-
cord-327272-fspxett8	22	27	.	.	.
cord-327272-fspxett8	23	1	However	however	RB
cord-327272-fspxett8	23	2	,	,	,
cord-327272-fspxett8	23	3	a	a	DT
cord-327272-fspxett8	23	4	trial	trial	NN
cord-327272-fspxett8	23	5	conducted	conduct	VBN
cord-327272-fspxett8	23	6	in	in	IN
cord-327272-fspxett8	23	7	China	China	NNP
cord-327272-fspxett8	23	8	showed	show	VBD
cord-327272-fspxett8	23	9	Remdesivir	Remdesivir	NNP
cord-327272-fspxett8	23	10	did	do	VBD
cord-327272-fspxett8	23	11	not	not	RB
cord-327272-fspxett8	23	12	improve	improve	VB
cord-327272-fspxett8	23	13	patients	patient	NNS
cord-327272-fspxett8	23	14	'	'	POS
cord-327272-fspxett8	23	15	condition	condition	NN
cord-327272-fspxett8	23	16	nor	nor	CC
cord-327272-fspxett8	23	17	reduced	reduce	VBD
cord-327272-fspxett8	23	18	the	the	DT
cord-327272-fspxett8	23	19	positivity	positivity	NN
cord-327272-fspxett8	23	20	to	to	IN
cord-327272-fspxett8	23	21	virus	virus	NN
cord-327272-fspxett8	23	22	.	.	.
cord-327272-fspxett8	24	1	Moreover	moreover	RB
cord-327272-fspxett8	24	2	,	,	,
cord-327272-fspxett8	24	3	the	the	DT
cord-327272-fspxett8	24	4	drug	drug	NN
cord-327272-fspxett8	24	5	showed	show	VBD
cord-327272-fspxett8	24	6	also	also	RB
cord-327272-fspxett8	24	7	significant	significant	JJ
cord-327272-fspxett8	24	8	side	side	NN
cord-327272-fspxett8	24	9	effects	effect	NNS
cord-327272-fspxett8	24	10	(	(	-LRB-
cord-327272-fspxett8	24	11	https://www.ft.com/content/	https://www.ft.com/content/	NNP
cord-327272-fspxett8	24	12	0a4872d1	0a4872d1	CD
cord-327272-fspxett8	24	13	-	-	HYPH
cord-327272-fspxett8	24	14	4cac-4040	4cac-4040	CD
cord-327272-fspxett8	24	15	-	-	HYPH
cord-327272-fspxett8	24	16	846f	846f	NNP
cord-327272-fspxett8	24	17	-	-	HYPH
cord-327272-fspxett8	24	18	ce32daa09d99	ce32daa09d99	NNP
cord-327272-fspxett8	24	19	)	)	-RRB-
cord-327272-fspxett8	24	20	.	.	.
cord-327272-fspxett8	25	1	In	in	IN
cord-327272-fspxett8	25	2	the	the	DT
cord-327272-fspxett8	25	3	search	search	NN
cord-327272-fspxett8	25	4	of	of	IN
cord-327272-fspxett8	25	5	the	the	DT
cord-327272-fspxett8	25	6	potential	potential	JJ
cord-327272-fspxett8	25	7	best	good	JJS
cord-327272-fspxett8	25	8	candidate	candidate	NN
cord-327272-fspxett8	25	9	drugs	drug	NNS
cord-327272-fspxett8	25	10	to	to	TO
cord-327272-fspxett8	25	11	be	be	VB
cord-327272-fspxett8	25	12	repositioned	reposition	VBN
cord-327272-fspxett8	25	13	,	,	,
cord-327272-fspxett8	25	14	structural	structural	JJ
cord-327272-fspxett8	25	15	analyses	analysis	NNS
cord-327272-fspxett8	25	16	comparing	compare	VBG
cord-327272-fspxett8	25	17	target	target	NN
cord-327272-fspxett8	25	18	molecules	molecule	NNS
cord-327272-fspxett8	25	19	in	in	IN
cord-327272-fspxett8	25	20	the	the	DT
cord-327272-fspxett8	25	21	different	different	JJ
cord-327272-fspxett8	25	22	pathogens	pathogen	NNS
cord-327272-fspxett8	25	23	should	should	MD
cord-327272-fspxett8	25	24	be	be	VB
cord-327272-fspxett8	25	25	applied	apply	VBN
cord-327272-fspxett8	25	26	in	in	IN
cord-327272-fspxett8	25	27	order	order	NN
cord-327272-fspxett8	25	28	to	to	TO
cord-327272-fspxett8	25	29	guide	guide	VB
cord-327272-fspxett8	25	30	a	a	DT
cord-327272-fspxett8	25	31	knowledge	knowledge	NN
cord-327272-fspxett8	25	32	-	-	HYPH
cord-327272-fspxett8	25	33	based	base	VBN
cord-327272-fspxett8	25	34	decision	decision	NN
cord-327272-fspxett8	25	35	process	process	NN
cord-327272-fspxett8	25	36	[	[	-LRB-
cord-327272-fspxett8	25	37	9	9	CD
cord-327272-fspxett8	25	38	]	]	-RRB-
cord-327272-fspxett8	25	39	.	.	.
cord-327272-fspxett8	26	1	In	in	IN
cord-327272-fspxett8	26	2	the	the	DT
cord-327272-fspxett8	26	3	specific	specific	JJ
cord-327272-fspxett8	26	4	case	case	NN
cord-327272-fspxett8	26	5	of	of	IN
cord-327272-fspxett8	26	6	SARS	SARS	NNP
cord-327272-fspxett8	26	7	-	-	HYPH
cord-327272-fspxett8	26	8	CoV-2	CoV-2	NNP
cord-327272-fspxett8	26	9	,	,	,
cord-327272-fspxett8	26	10	and	and	CC
cord-327272-fspxett8	26	11	in	in	IN
cord-327272-fspxett8	26	12	general	general	JJ
cord-327272-fspxett8	26	13	in	in	IN
cord-327272-fspxett8	26	14	the	the	DT
cord-327272-fspxett8	26	15	case	case	NN
cord-327272-fspxett8	26	16	of	of	IN
cord-327272-fspxett8	26	17	RNA	RNA	NNP
cord-327272-fspxett8	26	18	viruses	virus	NNS
cord-327272-fspxett8	26	19	,	,	,
cord-327272-fspxett8	26	20	the	the	DT
cord-327272-fspxett8	26	21	most	most	RBS
cord-327272-fspxett8	26	22	specific	specific	JJ
cord-327272-fspxett8	26	23	target	target	NN
cord-327272-fspxett8	26	24	is	be	VBZ
cord-327272-fspxett8	26	25	represented	represent	VBN
cord-327272-fspxett8	26	26	by	by	IN
cord-327272-fspxett8	26	27	the	the	DT
cord-327272-fspxett8	26	28	RNA	RNA	NNP
cord-327272-fspxett8	26	29	-	-	HYPH
cord-327272-fspxett8	26	30	dependent	dependent	JJ
cord-327272-fspxett8	26	31	RNA	rna	NN
cord-327272-fspxett8	26	32	-	-	HYPH
cord-327272-fspxett8	26	33	polymerase	polymerase	NN
cord-327272-fspxett8	26	34	(	(	-LRB-
cord-327272-fspxett8	26	35	RdRp	RdRp	NNP
cord-327272-fspxett8	26	36	)	)	-RRB-
cord-327272-fspxett8	26	37	which	which	WDT
cord-327272-fspxett8	26	38	is	be	VBZ
cord-327272-fspxett8	26	39	specific	specific	JJ
cord-327272-fspxett8	26	40	to	to	IN
cord-327272-fspxett8	26	41	each	each	DT
cord-327272-fspxett8	26	42	RNA	RNA	NNP
cord-327272-fspxett8	26	43	virus	virus	NN
cord-327272-fspxett8	26	44	,	,	,
cord-327272-fspxett8	26	45	regardless	regardless	RB
cord-327272-fspxett8	26	46	the	the	DT
cord-327272-fspxett8	26	47	polarity	polarity	NN
cord-327272-fspxett8	26	48	of	of	IN
cord-327272-fspxett8	26	49	the	the	DT
cord-327272-fspxett8	26	50	viral	viral	JJ
cord-327272-fspxett8	26	51	RNA	RNA	NNP
cord-327272-fspxett8	26	52	genome	genome	NN
cord-327272-fspxett8	26	53	[	[	-LRB-
cord-327272-fspxett8	26	54	10	10	CD
cord-327272-fspxett8	26	55	,	,	,
cord-327272-fspxett8	26	56	11	11	CD
cord-327272-fspxett8	26	57	]	]	-RRB-
cord-327272-fspxett8	26	58	.	.	.
cord-327272-fspxett8	27	1	Nevertheless	nevertheless	RB
cord-327272-fspxett8	27	2	,	,	,
cord-327272-fspxett8	27	3	significant	significant	JJ
cord-327272-fspxett8	27	4	differences	difference	NNS
cord-327272-fspxett8	27	5	are	be	VBP
cord-327272-fspxett8	27	6	identified	identify	VBN
cord-327272-fspxett8	27	7	between	between	IN
cord-327272-fspxett8	27	8	RdRp	RdRp	NNP
cord-327272-fspxett8	27	9	from	from	IN
cord-327272-fspxett8	27	10	positive	positive	JJ
cord-327272-fspxett8	27	11	-	-	HYPH
cord-327272-fspxett8	27	12	sense	sense	NN
cord-327272-fspxett8	27	13	and	and	CC
cord-327272-fspxett8	27	14	negative	negative	JJ
cord-327272-fspxett8	27	15	-	-	HYPH
cord-327272-fspxett8	27	16	sense	sense	NN
cord-327272-fspxett8	27	17	RNA	RNA	NNP
cord-327272-fspxett8	27	18	viruses	virus	NNS
cord-327272-fspxett8	27	19	[	[	-LRB-
cord-327272-fspxett8	27	20	12	12	CD
cord-327272-fspxett8	27	21	]	]	-RRB-
cord-327272-fspxett8	27	22	.	.	.
cord-327272-fspxett8	28	1	The	the	DT
cord-327272-fspxett8	28	2	latter	latter	JJ
cord-327272-fspxett8	28	3	observation	observation	NN
cord-327272-fspxett8	28	4	strongly	strongly	RB
cord-327272-fspxett8	28	5	suggests	suggest	VBZ
cord-327272-fspxett8	28	6	that	that	IN
cord-327272-fspxett8	28	7	repositioning	repositioning	NN
cord-327272-fspxett8	28	8	of	of	IN
cord-327272-fspxett8	28	9	antiviral	antiviral	JJ
cord-327272-fspxett8	28	10	drugs	drug	NNS
cord-327272-fspxett8	28	11	should	should	MD
cord-327272-fspxett8	28	12	take	take	VB
cord-327272-fspxett8	28	13	into	into	IN
cord-327272-fspxett8	28	14	consideration	consideration	NN
cord-327272-fspxett8	28	15	the	the	DT
cord-327272-fspxett8	28	16	molecular	molecular	JJ
cord-327272-fspxett8	28	17	basis	basis	NN
cord-327272-fspxett8	28	18	of	of	IN
cord-327272-fspxett8	28	19	the	the	DT
cord-327272-fspxett8	28	20	genomic	genomic	JJ
cord-327272-fspxett8	28	21	viral	viral	JJ
cord-327272-fspxett8	28	22	RNA	RNA	NNP
cord-327272-fspxett8	28	23	.	.	.
cord-327272-fspxett8	29	1	SARS	SARS	NNP
cord-327272-fspxett8	29	2	-	-	HYPH
cord-327272-fspxett8	29	3	CoV-2	CoV-2	NNP
cord-327272-fspxett8	29	4	is	be	VBZ
cord-327272-fspxett8	29	5	a	a	DT
cord-327272-fspxett8	29	6	positive	positive	JJ
cord-327272-fspxett8	29	7	-	-	HYPH
cord-327272-fspxett8	29	8	sense	sense	NN
cord-327272-fspxett8	29	9	RNA	RNA	NNP
cord-327272-fspxett8	29	10	virus	virus	NN
cord-327272-fspxett8	29	11	.	.	.
cord-327272-fspxett8	30	1	The	the	DT
cord-327272-fspxett8	30	2	only	only	JJ
cord-327272-fspxett8	30	3	positive	positive	JJ
cord-327272-fspxett8	30	4	-	-	HYPH
cord-327272-fspxett8	30	5	sense	sense	NN
cord-327272-fspxett8	30	6	RNA	RNA	NNP
cord-327272-fspxett8	30	7	virus	virus	NN
cord-327272-fspxett8	30	8	,	,	,
cord-327272-fspxett8	30	9	for	for	IN
cord-327272-fspxett8	30	10	which	which	WDT
cord-327272-fspxett8	30	11	a	a	DT
cord-327272-fspxett8	30	12	very	very	RB
cord-327272-fspxett8	30	13	effective	effective	JJ
cord-327272-fspxett8	30	14	drug	drug	NN
cord-327272-fspxett8	30	15	targeting	target	VBG
cord-327272-fspxett8	30	16	specifically	specifically	RB
cord-327272-fspxett8	30	17	the	the	DT
cord-327272-fspxett8	30	18	RdRp	RdRp	NNP
cord-327272-fspxett8	30	19	is	be	VBZ
cord-327272-fspxett8	30	20	available	available	JJ
cord-327272-fspxett8	30	21	and	and	CC
cord-327272-fspxett8	30	22	approved	approve	VBN
cord-327272-fspxett8	30	23	world	world	NN
cord-327272-fspxett8	30	24	-	-	HYPH
cord-327272-fspxett8	30	25	wide	wide	RB
cord-327272-fspxett8	30	26	for	for	IN
cord-327272-fspxett8	30	27	clinical	clinical	JJ
cord-327272-fspxett8	30	28	use	use	NN
cord-327272-fspxett8	30	29	,	,	,
cord-327272-fspxett8	30	30	is	be	VBZ
cord-327272-fspxett8	30	31	hepatitis	hepatitis	NN
cord-327272-fspxett8	30	32	C	C	NNP
cord-327272-fspxett8	30	33	virus	virus	NN
cord-327272-fspxett8	30	34	(	(	-LRB-
cord-327272-fspxett8	30	35	HCV	HCV	NNP
cord-327272-fspxett8	30	36	)	)	-RRB-
cord-327272-fspxett8	30	37	.	.	.
cord-327272-fspxett8	31	1	In	in	IN
cord-327272-fspxett8	31	2	the	the	DT
cord-327272-fspxett8	31	3	specific	specific	JJ
cord-327272-fspxett8	31	4	,	,	,
cord-327272-fspxett8	31	5	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	31	6	(	(	-LRB-
cord-327272-fspxett8	31	7	Sovaldi	Sovaldi	NNP
cord-327272-fspxett8	31	8	®	®	''
cord-327272-fspxett8	31	9	;	;	:
cord-327272-fspxett8	31	10	Epclusa	Epclusa	NNP
cord-327272-fspxett8	31	11	®	®	NNP
cord-327272-fspxett8	31	12	by	by	IN
cord-327272-fspxett8	31	13	Gilead	Gilead	NNP
cord-327272-fspxett8	31	14	)	)	-RRB-
cord-327272-fspxett8	31	15	is	be	VBZ
cord-327272-fspxett8	31	16	a	a	DT
cord-327272-fspxett8	31	17	direct	direct	JJ
cord-327272-fspxett8	31	18	antiviral	antiviral	JJ
cord-327272-fspxett8	31	19	agent	agent	NN
cord-327272-fspxett8	31	20	(	(	-LRB-
cord-327272-fspxett8	31	21	DAA	DAA	NNP
cord-327272-fspxett8	31	22	)	)	-RRB-
cord-327272-fspxett8	31	23	that	that	WDT
cord-327272-fspxett8	31	24	inhibits	inhibit	VBZ
cord-327272-fspxett8	31	25	the	the	DT
cord-327272-fspxett8	31	26	hepatitis	hepatitis	NN
cord-327272-fspxett8	31	27	C	C	NNP
cord-327272-fspxett8	31	28	NS5B	NS5B	NNP
cord-327272-fspxett8	31	29	RdRp	RdRp	NNP
cord-327272-fspxett8	31	30	protein	protein	NN
cord-327272-fspxett8	31	31	[	[	-LRB-
cord-327272-fspxett8	31	32	13	13	CD
cord-327272-fspxett8	31	33	]	]	-RRB-
cord-327272-fspxett8	31	34	.	.	.
cord-327272-fspxett8	32	1	Interestingly	interestingly	RB
cord-327272-fspxett8	32	2	,	,	,
cord-327272-fspxett8	32	3	it	-PRON-	PRP
cord-327272-fspxett8	32	4	has	have	VBZ
cord-327272-fspxett8	32	5	been	be	VBN
cord-327272-fspxett8	32	6	already	already	RB
cord-327272-fspxett8	32	7	shown	show	VBN
cord-327272-fspxett8	32	8	to	to	TO
cord-327272-fspxett8	32	9	be	be	VB
cord-327272-fspxett8	32	10	effective	effective	JJ
cord-327272-fspxett8	32	11	in	in	IN
cord-327272-fspxett8	32	12	vitro	vitro	FW
cord-327272-fspxett8	32	13	and	and	CC
cord-327272-fspxett8	32	14	in	in	IN
cord-327272-fspxett8	32	15	humans	human	NNS
cord-327272-fspxett8	32	16	for	for	IN
cord-327272-fspxett8	32	17	other	other	JJ
cord-327272-fspxett8	32	18	two	two	CD
cord-327272-fspxett8	32	19	different	different	JJ
cord-327272-fspxett8	32	20	positive	positive	JJ
cord-327272-fspxett8	32	21	-	-	HYPH
cord-327272-fspxett8	32	22	sense	sense	NN
cord-327272-fspxett8	32	23	RNA	RNA	NNP
cord-327272-fspxett8	32	24	viruses	virus	NNS
cord-327272-fspxett8	32	25	,	,	,
cord-327272-fspxett8	32	26	namely	namely	RB
cord-327272-fspxett8	32	27	Yellow	Yellow	NNP
cord-327272-fspxett8	32	28	Fever	Fever	NNP
cord-327272-fspxett8	32	29	and	and	CC
cord-327272-fspxett8	32	30	Hepatitis	Hepatitis	NNP
cord-327272-fspxett8	32	31	A	A	NNP
cord-327272-fspxett8	32	32	virus	virus	NN
cord-327272-fspxett8	32	33	[	[	-LRB-
cord-327272-fspxett8	32	34	14	14	CD
cord-327272-fspxett8	32	35	,	,	,
cord-327272-fspxett8	32	36	15	15	CD
cord-327272-fspxett8	32	37	]	]	-RRB-
cord-327272-fspxett8	32	38	.	.	.
cord-327272-fspxett8	33	1	The	the	DT
cord-327272-fspxett8	33	2	alignment	alignment	NN
cord-327272-fspxett8	33	3	of	of	IN
cord-327272-fspxett8	33	4	RdRp	RdRp	NNP
cord-327272-fspxett8	33	5	sequences	sequence	NNS
cord-327272-fspxett8	33	6	from	from	IN
cord-327272-fspxett8	33	7	HCV	HCV	NNP
cord-327272-fspxett8	33	8	and	and	CC
cord-327272-fspxett8	33	9	the	the	DT
cord-327272-fspxett8	33	10	three	three	CD
cord-327272-fspxett8	33	11	epidemic	epidemic	NN
cord-327272-fspxett8	33	12	/	/	SYM
cord-327272-fspxett8	33	13	pandemic	pandemic	NN
cord-327272-fspxett8	33	14	coronaviruses	coronaviruse	NNS
cord-327272-fspxett8	33	15	,	,	,
cord-327272-fspxett8	33	16	confirms	confirm	VBZ
cord-327272-fspxett8	33	17	the	the	DT
cord-327272-fspxett8	33	18	high	high	JJ
cord-327272-fspxett8	33	19	homology	homology	NN
cord-327272-fspxett8	33	20	and	and	CC
cord-327272-fspxett8	33	21	conservation	conservation	NN
cord-327272-fspxett8	33	22	in	in	IN
cord-327272-fspxett8	33	23	several	several	JJ
cord-327272-fspxett8	33	24	residues	residue	NNS
cord-327272-fspxett8	33	25	along	along	IN
cord-327272-fspxett8	33	26	the	the	DT
cord-327272-fspxett8	33	27	sequence	sequence	NN
cord-327272-fspxett8	33	28	and	and	CC
cord-327272-fspxett8	33	29	in	in	IN
cord-327272-fspxett8	33	30	particular	particular	JJ
cord-327272-fspxett8	33	31	in	in	IN
cord-327272-fspxett8	33	32	the	the	DT
cord-327272-fspxett8	33	33	Motif	motif	NN
cord-327272-fspxett8	33	34	B	B	NNP
cord-327272-fspxett8	33	35	and	and	CC
cord-327272-fspxett8	33	36	C.	c.	NN
cord-327272-fspxett8	34	1	On	on	IN
cord-327272-fspxett8	34	2	the	the	DT
cord-327272-fspxett8	34	3	contrary	contrary	NN
cord-327272-fspxett8	34	4	,	,	,
cord-327272-fspxett8	34	5	such	such	JJ
cord-327272-fspxett8	34	6	homology	homology	NN
cord-327272-fspxett8	34	7	is	be	VBZ
cord-327272-fspxett8	34	8	almost	almost	RB
cord-327272-fspxett8	34	9	lost	lose	VBN
cord-327272-fspxett8	34	10	when	when	WRB
cord-327272-fspxett8	34	11	RdRp	RdRp	NNP
cord-327272-fspxett8	34	12	sequences	sequence	NNS
cord-327272-fspxett8	34	13	from	from	IN
cord-327272-fspxett8	34	14	the	the	DT
cord-327272-fspxett8	34	15	three	three	CD
cord-327272-fspxett8	34	16	epidemic	epidemic	NN
cord-327272-fspxett8	34	17	/	/	SYM
cord-327272-fspxett8	34	18	pandemic	pandemic	NN
cord-327272-fspxett8	34	19	coronaviruses	coronaviruse	NNS
cord-327272-fspxett8	34	20	are	be	VBP
cord-327272-fspxett8	34	21	aligned	align	VBN
cord-327272-fspxett8	34	22	with	with	IN
cord-327272-fspxett8	34	23	those	those	DT
cord-327272-fspxett8	34	24	from	from	IN
cord-327272-fspxett8	34	25	negativesense	negativesense	NNP
cord-327272-fspxett8	34	26	RNA	RNA	NNP
cord-327272-fspxett8	34	27	viruses	virus	NNS
cord-327272-fspxett8	34	28	,	,	,
cord-327272-fspxett8	34	29	namely	namely	RB
cord-327272-fspxett8	34	30	Ebola	Ebola	NNP
cord-327272-fspxett8	34	31	,	,	,
cord-327272-fspxett8	34	32	Influenza	Influenza	NNP
cord-327272-fspxett8	34	33	,	,	,
cord-327272-fspxett8	34	34	Rabies	Rabies	NNP
cord-327272-fspxett8	34	35	and	and	CC
cord-327272-fspxett8	34	36	Vesicular	Vesicular	NNP
cord-327272-fspxett8	34	37	Stomatitis	Stomatitis	NNP
cord-327272-fspxett8	34	38	viruses	virus	NNS
cord-327272-fspxett8	34	39	[	[	-LRB-
cord-327272-fspxett8	34	40	16	16	CD
cord-327272-fspxett8	34	41	]	]	-RRB-
cord-327272-fspxett8	34	42	.	.	.
cord-327272-fspxett8	35	1	The	the	DT
cord-327272-fspxett8	35	2	structure	structure	NN
cord-327272-fspxett8	35	3	modeling	modeling	NN
cord-327272-fspxett8	35	4	shows	show	VBZ
cord-327272-fspxett8	35	5	that	that	IN
cord-327272-fspxett8	35	6	RdRp	RdRp	NNP
cord-327272-fspxett8	35	7	of	of	IN
cord-327272-fspxett8	35	8	positivesense	positivesense	NNP
cord-327272-fspxett8	35	9	(	(	-LRB-
cord-327272-fspxett8	35	10	HCV	HCV	NNP
cord-327272-fspxett8	35	11	and	and	CC
cord-327272-fspxett8	35	12	SARS	SARS	NNP
cord-327272-fspxett8	35	13	-	-	HYPH
cord-327272-fspxett8	35	14	CoV-2	CoV-2	NNP
cord-327272-fspxett8	35	15	)	)	-RRB-
cord-327272-fspxett8	35	16	and	and	CC
cord-327272-fspxett8	35	17	negative	negative	JJ
cord-327272-fspxett8	35	18	-	-	HYPH
cord-327272-fspxett8	35	19	sense	sense	NN
cord-327272-fspxett8	36	1	(	(	-LRB-
cord-327272-fspxett8	36	2	i.e.	i.e.	FW
cord-327272-fspxett8	36	3	Influenza	Influenza	NNP
cord-327272-fspxett8	36	4	)	)	-RRB-
cord-327272-fspxett8	36	5	RNA	RNA	NNP
cord-327272-fspxett8	36	6	viruses	virus	NNS
cord-327272-fspxett8	36	7	are	be	VBP
cord-327272-fspxett8	36	8	significantly	significantly	RB
cord-327272-fspxett8	36	9	different	different	JJ
cord-327272-fspxett8	36	10	,	,	,
cord-327272-fspxett8	36	11	but	but	CC
cord-327272-fspxett8	36	12	they	-PRON-	PRP
cord-327272-fspxett8	36	13	all	all	DT
cord-327272-fspxett8	36	14	show	show	VBP
cord-327272-fspxett8	36	15	the	the	DT
cord-327272-fspxett8	36	16	formation	formation	NN
cord-327272-fspxett8	36	17	of	of	IN
cord-327272-fspxett8	36	18	the	the	DT
cord-327272-fspxett8	36	19	Motif	motif	NN
cord-327272-fspxett8	36	20	C	C	NNP
cord-327272-fspxett8	36	21	β	β	NN
cord-327272-fspxett8	36	22	-	-	HYPH
cord-327272-fspxett8	36	23	strandloop	strandloop	NNP
cord-327272-fspxett8	36	24	-	-	HYPH
cord-327272-fspxett8	36	25	β	β	NN
cord-327272-fspxett8	36	26	-	-	HYPH
cord-327272-fspxett8	36	27	strand	strand	NN
cord-327272-fspxett8	36	28	structure	structure	NN
cord-327272-fspxett8	36	29	.	.	.
cord-327272-fspxett8	37	1	However	however	RB
cord-327272-fspxett8	37	2	,	,	,
cord-327272-fspxett8	37	3	only	only	RB
cord-327272-fspxett8	37	4	the	the	DT
cord-327272-fspxett8	37	5	alignment	alignment	NN
cord-327272-fspxett8	37	6	of	of	IN
cord-327272-fspxett8	37	7	RdRp	RdRp	NNP
cord-327272-fspxett8	37	8	structures	structure	NNS
cord-327272-fspxett8	37	9	from	from	IN
cord-327272-fspxett8	37	10	the	the	DT
cord-327272-fspxett8	37	11	two	two	CD
cord-327272-fspxett8	37	12	positive	positive	JJ
cord-327272-fspxett8	37	13	-	-	HYPH
cord-327272-fspxett8	37	14	sense	sense	NN
cord-327272-fspxett8	37	15	RNA	RNA	NNP
cord-327272-fspxett8	37	16	viruses	virus	NNS
cord-327272-fspxett8	37	17	shows	show	VBZ
cord-327272-fspxett8	37	18	a	a	DT
cord-327272-fspxett8	37	19	superimposition	superimposition	NN
cord-327272-fspxett8	37	20	of	of	IN
cord-327272-fspxett8	37	21	the	the	DT
cord-327272-fspxett8	37	22	two	two	CD
cord-327272-fspxett8	37	23	Motifs	motif	NNS
cord-327272-fspxett8	37	24	C	C	NNP
cord-327272-fspxett8	37	25	[	[	-LRB-
cord-327272-fspxett8	37	26	16	16	CD
cord-327272-fspxett8	37	27	]	]	-RRB-
cord-327272-fspxett8	37	28	.	.	.
cord-327272-fspxett8	38	1	All	all	PDT
cord-327272-fspxett8	38	2	these	these	DT
cord-327272-fspxett8	38	3	sequence	sequence	NN
cord-327272-fspxett8	38	4	and	and	CC
cord-327272-fspxett8	38	5	structural	structural	JJ
cord-327272-fspxett8	38	6	modelling	modelling	NN
cord-327272-fspxett8	38	7	evidences	evidence	NNS
cord-327272-fspxett8	38	8	strongly	strongly	RB
cord-327272-fspxett8	38	9	support	support	VBP
cord-327272-fspxett8	38	10	the	the	DT
cord-327272-fspxett8	38	11	concept	concept	NN
cord-327272-fspxett8	38	12	that	that	IN
cord-327272-fspxett8	38	13	the	the	DT
cord-327272-fspxett8	38	14	SARS	SARS	NNP
cord-327272-fspxett8	38	15	-	-	HYPH
cord-327272-fspxett8	38	16	CoV-2	CoV-2	NNP
cord-327272-fspxett8	38	17	RdRp	RdRp	NNP
cord-327272-fspxett8	38	18	is	be	VBZ
cord-327272-fspxett8	38	19	much	much	RB
cord-327272-fspxett8	38	20	more	more	RBR
cord-327272-fspxett8	38	21	similar	similar	JJ
cord-327272-fspxett8	38	22	to	to	IN
cord-327272-fspxett8	38	23	the	the	DT
cord-327272-fspxett8	38	24	one	one	NN
cord-327272-fspxett8	38	25	from	from	IN
cord-327272-fspxett8	38	26	HCV	HCV	NNP
cord-327272-fspxett8	38	27	than	than	IN
cord-327272-fspxett8	38	28	the	the	DT
cord-327272-fspxett8	38	29	one	one	CD
cord-327272-fspxett8	38	30	from	from	IN
cord-327272-fspxett8	38	31	negative	negative	JJ
cord-327272-fspxett8	38	32	-	-	HYPH
cord-327272-fspxett8	38	33	sense	sense	NN
cord-327272-fspxett8	38	34	Influenza	Influenza	NNP
cord-327272-fspxett8	38	35	and	and	CC
cord-327272-fspxett8	38	36	Ebola	Ebola	NNP
cord-327272-fspxett8	38	37	RNA	RNA	NNP
cord-327272-fspxett8	38	38	viruses	virus	NNS
cord-327272-fspxett8	38	39	.	.	.
cord-327272-fspxett8	39	1	Therefore	therefore	RB
cord-327272-fspxett8	39	2	,	,	,
cord-327272-fspxett8	39	3	repositioning	reposition	VBG
cord-327272-fspxett8	39	4	of	of	IN
cord-327272-fspxett8	39	5	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	39	6	(	(	-LRB-
cord-327272-fspxett8	39	7	Sovaldi	Sovaldi	NNP
cord-327272-fspxett8	39	8	®	®	''
cord-327272-fspxett8	39	9	;	;	:
cord-327272-fspxett8	39	10	Epclusa	Epclusa	NNP
cord-327272-fspxett8	39	11	®	®	NNP
cord-327272-fspxett8	39	12	by	by	IN
cord-327272-fspxett8	39	13	Gilead	Gilead	NNP
cord-327272-fspxett8	39	14	)	)	-RRB-
cord-327272-fspxett8	39	15	,	,	,
cord-327272-fspxett8	39	16	the	the	DT
cord-327272-fspxett8	39	17	inhibitor	inhibitor	NN
cord-327272-fspxett8	39	18	of	of	IN
cord-327272-fspxett8	39	19	the	the	DT
cord-327272-fspxett8	39	20	HCV	HCV	NNP
cord-327272-fspxett8	39	21	NS5B	NS5B	NNP
cord-327272-fspxett8	39	22	RdRp	RdRp	NNP
cord-327272-fspxett8	39	23	protein	protein	NN
cord-327272-fspxett8	39	24	,	,	,
cord-327272-fspxett8	39	25	as	as	RB
cord-327272-fspxett8	39	26	antiviral	antiviral	JJ
cord-327272-fspxett8	39	27	in	in	IN
cord-327272-fspxett8	39	28	the	the	DT
cord-327272-fspxett8	39	29	treatment	treatment	NN
cord-327272-fspxett8	39	30	of	of	IN
cord-327272-fspxett8	39	31	the	the	DT
cord-327272-fspxett8	39	32	SARS	SARS	NNP
cord-327272-fspxett8	39	33	-	-	HYPH
cord-327272-fspxett8	39	34	CoV-2	CoV-2	NNP
cord-327272-fspxett8	39	35	infection	infection	NN
cord-327272-fspxett8	39	36	has	have	VBZ
cord-327272-fspxett8	39	37	an	an	DT
cord-327272-fspxett8	39	38	extremely	extremely	RB
cord-327272-fspxett8	39	39	high	high	JJ
cord-327272-fspxett8	39	40	potentiality	potentiality	NN
cord-327272-fspxett8	39	41	of	of	IN
cord-327272-fspxett8	39	42	success	success	NN
cord-327272-fspxett8	39	43	,	,	,
cord-327272-fspxett8	39	44	as	as	IN
cord-327272-fspxett8	39	45	recently	recently	RB
cord-327272-fspxett8	39	46	postulated	postulate	VBN
cord-327272-fspxett8	39	47	by	by	IN
cord-327272-fspxett8	39	48	others	other	NNS
cord-327272-fspxett8	39	49	[	[	-LRB-
cord-327272-fspxett8	39	50	17	17	CD
cord-327272-fspxett8	39	51	]	]	-RRB-
cord-327272-fspxett8	39	52	,	,	,
cord-327272-fspxett8	39	53	and	and	CC
cord-327272-fspxett8	39	54	is	be	VBZ
cord-327272-fspxett8	39	55	suggested	suggest	VBN
cord-327272-fspxett8	39	56	as	as	IN
cord-327272-fspxett8	39	57	a	a	DT
cord-327272-fspxett8	39	58	potential	potential	JJ
cord-327272-fspxett8	39	59	drug	drug	NN
cord-327272-fspxett8	39	60	for	for	IN
cord-327272-fspxett8	39	61	the	the	DT
cord-327272-fspxett8	39	62	treatment	treatment	NN
cord-327272-fspxett8	39	63	of	of	IN
cord-327272-fspxett8	39	64	COVID-19	COVID-19	NNP
cord-327272-fspxett8	39	65	in	in	IN
cord-327272-fspxett8	39	66	the	the	DT
cord-327272-fspxett8	39	67	very	very	RB
cord-327272-fspxett8	39	68	recent	recent	JJ
cord-327272-fspxett8	39	69	EASL	EASL	NNP
cord-327272-fspxett8	39	70	-	-	HYPH
cord-327272-fspxett8	39	71	ESCMID	ESCMID	NNP
cord-327272-fspxett8	39	72	position	position	NN
cord-327272-fspxett8	39	73	paper	paper	NN
cord-327272-fspxett8	39	74	[	[	-LRB-
cord-327272-fspxett8	39	75	18	18	CD
cord-327272-fspxett8	39	76	]	]	-RRB-
cord-327272-fspxett8	39	77	.	.	.
cord-327272-fspxett8	40	1	This	this	DT
cord-327272-fspxett8	40	2	is	be	VBZ
cord-327272-fspxett8	40	3	further	further	RB
cord-327272-fspxett8	40	4	supported	support	VBN
cord-327272-fspxett8	40	5	by	by	IN
cord-327272-fspxett8	40	6	the	the	DT
cord-327272-fspxett8	40	7	great	great	JJ
cord-327272-fspxett8	40	8	diversity	diversity	NN
cord-327272-fspxett8	40	9	between	between	IN
cord-327272-fspxett8	40	10	the	the	DT
cord-327272-fspxett8	40	11	molecular	molecular	JJ
cord-327272-fspxett8	40	12	structure	structure	NN
cord-327272-fspxett8	40	13	of	of	IN
cord-327272-fspxett8	40	14	the	the	DT
cord-327272-fspxett8	40	15	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	40	16	and	and	CC
cord-327272-fspxett8	40	17	the	the	DT
cord-327272-fspxett8	40	18	inhibitors	inhibitor	NNS
cord-327272-fspxett8	40	19	of	of	IN
cord-327272-fspxett8	40	20	Influenza	Influenza	NNP
cord-327272-fspxett8	40	21	and	and	CC
cord-327272-fspxett8	40	22	Ebola	Ebola	NNP
cord-327272-fspxett8	40	23	viruses	virus	NNS
cord-327272-fspxett8	40	24	currently	currently	RB
cord-327272-fspxett8	40	25	evaluated	evaluate	VBN
cord-327272-fspxett8	40	26	in	in	IN
cord-327272-fspxett8	40	27	clinical	clinical	JJ
cord-327272-fspxett8	40	28	trials	trial	NNS
cord-327272-fspxett8	41	1	(	(	-LRB-
cord-327272-fspxett8	41	2	Fig	Fig	NNP
cord-327272-fspxett8	41	3	.	.	NNP
cord-327272-fspxett8	41	4	1	1	CD
cord-327272-fspxett8	41	5	)	)	-RRB-
cord-327272-fspxett8	41	6	.	.	.
cord-327272-fspxett8	42	1	Moreover	moreover	RB
cord-327272-fspxett8	42	2	,	,	,
cord-327272-fspxett8	42	3	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	42	4	is	be	VBZ
cord-327272-fspxett8	42	5	a	a	DT
cord-327272-fspxett8	42	6	prodrug	prodrug	NN
cord-327272-fspxett8	42	7	of	of	IN
cord-327272-fspxett8	42	8	the	the	DT
cord-327272-fspxett8	42	9	protide	protide	JJ
cord-327272-fspxett8	42	10	type	type	NN
cord-327272-fspxett8	42	11	and	and	CC
cord-327272-fspxett8	42	12	is	be	VBZ
cord-327272-fspxett8	42	13	metabolized	metabolize	VBN
cord-327272-fspxett8	42	14	to	to	IN
cord-327272-fspxett8	42	15	the	the	DT
cord-327272-fspxett8	42	16	active	active	JJ
cord-327272-fspxett8	42	17	antiviral	antiviral	JJ
cord-327272-fspxett8	42	18	agent	agent	NN
cord-327272-fspxett8	42	19	GS-461203	GS-461203	NNP
cord-327272-fspxett8	42	20	(	(	-LRB-
cord-327272-fspxett8	42	21	2′-deoxy-2′-α	2′-deoxy-2′-α	CD
cord-327272-fspxett8	42	22	-	-	HYPH
cord-327272-fspxett8	42	23	fluoro	fluoro	NN
cord-327272-fspxett8	42	24	-	-	HYPH
cord-327272-fspxett8	42	25	β	β	NN
cord-327272-fspxett8	42	26	-	-	HYPH
cord-327272-fspxett8	42	27	C	C	NNP
cord-327272-fspxett8	42	28	-	-	HYPH
cord-327272-fspxett8	42	29	methyluridine-5′-triphosphate	methyluridine-5′-triphosphate	NNP
cord-327272-fspxett8	42	30	)	)	-RRB-
cord-327272-fspxett8	42	31	in	in	IN
cord-327272-fspxett8	42	32	the	the	DT
cord-327272-fspxett8	42	33	liver	liver	NN
cord-327272-fspxett8	42	34	.	.	.
cord-327272-fspxett8	43	1	The	the	DT
cord-327272-fspxett8	43	2	enzymes	enzyme	NNS
cord-327272-fspxett8	43	3	involved	involve	VBN
cord-327272-fspxett8	43	4	in	in	IN
cord-327272-fspxett8	43	5	such	such	JJ
cord-327272-fspxett8	43	6	activation	activation	NN
cord-327272-fspxett8	43	7	are	be	VBP
cord-327272-fspxett8	43	8	cathepsin	cathepsin	NN
cord-327272-fspxett8	43	9	A	a	NN
cord-327272-fspxett8	43	10	and	and	CC
cord-327272-fspxett8	43	11	the	the	DT
cord-327272-fspxett8	43	12	histidine	histidine	NN
cord-327272-fspxett8	43	13	triad	triad	NN
cord-327272-fspxett8	43	14	nucleotide	nucleotide	NN
cord-327272-fspxett8	43	15	-	-	HYPH
cord-327272-fspxett8	43	16	binding	bind	VBG
cord-327272-fspxett8	43	17	protein	protein	NN
cord-327272-fspxett8	43	18	1	1	CD
cord-327272-fspxett8	43	19	(	(	-LRB-
cord-327272-fspxett8	43	20	HINT1	HINT1	NNP
cord-327272-fspxett8	43	21	)	)	-RRB-
cord-327272-fspxett8	43	22	,	,	,
cord-327272-fspxett8	43	23	and	and	CC
cord-327272-fspxett8	43	24	subsequent	subsequent	JJ
cord-327272-fspxett8	43	25	repeated	repeat	VBN
cord-327272-fspxett8	43	26	phosphorylation	phosphorylation	NN
cord-327272-fspxett8	43	27	.	.	.
cord-327272-fspxett8	44	1	All	all	PDT
cord-327272-fspxett8	44	2	these	these	DT
cord-327272-fspxett8	44	3	enzymes	enzyme	NNS
cord-327272-fspxett8	44	4	have	have	VBP
cord-327272-fspxett8	44	5	RNA	RNA	NNP
cord-327272-fspxett8	44	6	and	and	CC
cord-327272-fspxett8	44	7	protein	protein	NN
cord-327272-fspxett8	44	8	expression	expression	NN
cord-327272-fspxett8	44	9	in	in	IN
cord-327272-fspxett8	44	10	the	the	DT
cord-327272-fspxett8	44	11	lung	lung	NN
cord-327272-fspxett8	44	12	cells	cell	NNS
cord-327272-fspxett8	44	13	comparable	comparable	JJ
cord-327272-fspxett8	44	14	to	to	IN
cord-327272-fspxett8	44	15	liver	liver	NN
cord-327272-fspxett8	44	16	cells	cell	NNS
cord-327272-fspxett8	44	17	,	,	,
cord-327272-fspxett8	44	18	ensuring	ensure	VBG
cord-327272-fspxett8	44	19	the	the	DT
cord-327272-fspxett8	44	20	appropriate	appropriate	JJ
cord-327272-fspxett8	44	21	activation	activation	NN
cord-327272-fspxett8	44	22	of	of	IN
cord-327272-fspxett8	44	23	the	the	DT
cord-327272-fspxett8	44	24	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	44	25	to	to	TO
cord-327272-fspxett8	44	26	become	become	VB
cord-327272-fspxett8	44	27	an	an	DT
cord-327272-fspxett8	44	28	effective	effective	JJ
cord-327272-fspxett8	44	29	substrate	substrate	NN
cord-327272-fspxett8	44	30	of	of	IN
cord-327272-fspxett8	44	31	the	the	DT
cord-327272-fspxett8	44	32	SARS	SARS	NNP
cord-327272-fspxett8	44	33	-	-	HYPH
cord-327272-fspxett8	44	34	CoV-2	CoV-2	NNP
cord-327272-fspxett8	44	35	RdRp	RdRp	NNP
cord-327272-fspxett8	44	36	in	in	IN
cord-327272-fspxett8	44	37	the	the	DT
cord-327272-fspxett8	44	38	target	target	NN
cord-327272-fspxett8	44	39	cells	cell	NNS
cord-327272-fspxett8	44	40	of	of	IN
cord-327272-fspxett8	44	41	the	the	DT
cord-327272-fspxett8	44	42	respiratory	respiratory	JJ
cord-327272-fspxett8	44	43	tract	tract	NN
cord-327272-fspxett8	44	44	.	.	.
cord-327272-fspxett8	45	1	In	in	IN
cord-327272-fspxett8	45	2	conclusion	conclusion	NN
cord-327272-fspxett8	45	3	,	,	,
cord-327272-fspxett8	45	4	the	the	DT
cord-327272-fspxett8	45	5	data	datum	NNS
cord-327272-fspxett8	45	6	here	here	RB
cord-327272-fspxett8	45	7	reported	report	VBN
cord-327272-fspxett8	45	8	indicate	indicate	VBP
cord-327272-fspxett8	45	9	the	the	DT
cord-327272-fspxett8	45	10	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	45	11	as	as	IN
cord-327272-fspxett8	45	12	the	the	DT
cord-327272-fspxett8	45	13	lead	lead	NN
cord-327272-fspxett8	45	14	compound	compound	NN
cord-327272-fspxett8	45	15	with	with	IN
cord-327272-fspxett8	45	16	the	the	DT
cord-327272-fspxett8	45	17	highest	high	JJS
cord-327272-fspxett8	45	18	potential	potential	NN
cord-327272-fspxett8	45	19	of	of	IN
cord-327272-fspxett8	45	20	antiviral	antiviral	JJ
cord-327272-fspxett8	45	21	efficacy	efficacy	NN
cord-327272-fspxett8	45	22	in	in	IN
cord-327272-fspxett8	45	23	SARS	SARS	NNP
cord-327272-fspxett8	45	24	-	-	HYPH
cord-327272-fspxett8	45	25	CoV-2	CoV-2	NNP
cord-327272-fspxett8	45	26	infection	infection	NN
cord-327272-fspxett8	45	27	.	.	.
cord-327272-fspxett8	46	1	In	in	IN
cord-327272-fspxett8	46	2	addition	addition	NN
cord-327272-fspxett8	46	3	,	,	,
cord-327272-fspxett8	46	4	the	the	DT
cord-327272-fspxett8	46	5	long	long	RB
cord-327272-fspxett8	46	6	-	-	HYPH
cord-327272-fspxett8	46	7	lasting	last	VBG
cord-327272-fspxett8	46	8	use	use	NN
cord-327272-fspxett8	46	9	in	in	IN
cord-327272-fspxett8	46	10	patients	patient	NNS
cord-327272-fspxett8	46	11	for	for	IN
cord-327272-fspxett8	46	12	treating	treat	VBG
cord-327272-fspxett8	46	13	and	and	CC
cord-327272-fspxett8	46	14	eradicating	eradicate	VBG
cord-327272-fspxett8	46	15	HCV	HCV	NNP
cord-327272-fspxett8	46	16	chronic	chronic	JJ
cord-327272-fspxett8	46	17	infection	infection	NN
cord-327272-fspxett8	46	18	provides	provide	VBZ
cord-327272-fspxett8	46	19	also	also	RB
cord-327272-fspxett8	46	20	the	the	DT
cord-327272-fspxett8	46	21	full	full	JJ
cord-327272-fspxett8	46	22	knowledge	knowledge	NN
cord-327272-fspxett8	46	23	of	of	IN
cord-327272-fspxett8	46	24	its	-PRON-	PRP$
cord-327272-fspxett8	46	25	safety	safety	NN
cord-327272-fspxett8	46	26	profile	profile	NN
cord-327272-fspxett8	46	27	[	[	-LRB-
cord-327272-fspxett8	46	28	13	13	CD
cord-327272-fspxett8	46	29	]	]	-RRB-
cord-327272-fspxett8	46	30	.	.	.
cord-327272-fspxett8	47	1	If	if	IN
cord-327272-fspxett8	47	2	the	the	DT
cord-327272-fspxett8	47	3	evaluation	evaluation	NN
cord-327272-fspxett8	47	4	in	in	IN
cord-327272-fspxett8	47	5	humans	human	NNS
cord-327272-fspxett8	47	6	will	will	MD
cord-327272-fspxett8	47	7	hold	hold	VB
cord-327272-fspxett8	47	8	the	the	DT
cord-327272-fspxett8	47	9	premises	premise	NNS
cord-327272-fspxett8	47	10	of	of	IN
cord-327272-fspxett8	47	11	the	the	DT
cord-327272-fspxett8	47	12	in	in	IN
cord-327272-fspxett8	47	13	silico	silico	NN
cord-327272-fspxett8	47	14	analyses	analysis	NNS
cord-327272-fspxett8	47	15	,	,	,
cord-327272-fspxett8	47	16	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	47	17	will	will	MD
cord-327272-fspxett8	47	18	become	become	VB
cord-327272-fspxett8	47	19	an	an	DT
cord-327272-fspxett8	47	20	extraordinary	extraordinary	JJ
cord-327272-fspxett8	47	21	therapeutic	therapeutic	JJ
cord-327272-fspxett8	47	22	tool	tool	NN
cord-327272-fspxett8	47	23	to	to	TO
cord-327272-fspxett8	47	24	inhibit	inhibit	VB
cord-327272-fspxett8	47	25	the	the	DT
cord-327272-fspxett8	47	26	SARS	SARS	NNP
cord-327272-fspxett8	47	27	-	-	HYPH
cord-327272-fspxett8	47	28	CoV-2	CoV-2	NNP
cord-327272-fspxett8	47	29	replication	replication	NN
cord-327272-fspxett8	47	30	and	and	CC
cord-327272-fspxett8	47	31	,	,	,
cord-327272-fspxett8	47	32	ultimately	ultimately	RB
cord-327272-fspxett8	47	33	,	,	,
cord-327272-fspxett8	47	34	to	to	TO
cord-327272-fspxett8	47	35	make	make	VB
cord-327272-fspxett8	47	36	the	the	DT
cord-327272-fspxett8	47	37	current	current	JJ
cord-327272-fspxett8	47	38	pandemic	pandemic	NN
cord-327272-fspxett8	47	39	a	a	DT
cord-327272-fspxett8	47	40	manageable	manageable	JJ
cord-327272-fspxett8	47	41	disease	disease	NN
cord-327272-fspxett8	47	42	.	.	.
cord-327272-fspxett8	48	1	The	the	DT
cord-327272-fspxett8	48	2	continuing	continue	VBG
cord-327272-fspxett8	48	3	2019-nCoV	2019-ncov	CD
cord-327272-fspxett8	48	4	epidemic	epidemic	NN
cord-327272-fspxett8	48	5	threat	threat	NN
cord-327272-fspxett8	48	6	of	of	IN
cord-327272-fspxett8	48	7	novel	novel	JJ
cord-327272-fspxett8	48	8	coronaviruses	coronaviruse	NNS
cord-327272-fspxett8	48	9	to	to	IN
cord-327272-fspxett8	48	10	global	global	JJ
cord-327272-fspxett8	48	11	health	health	NN
cord-327272-fspxett8	48	12	-the	-the	DT
cord-327272-fspxett8	48	13	latest	late	JJS
cord-327272-fspxett8	48	14	2019	2019	CD
cord-327272-fspxett8	48	15	novel	novel	JJ
cord-327272-fspxett8	48	16	coronavirus	coronavirus	NN
cord-327272-fspxett8	48	17	outbreak	outbreak	NN
cord-327272-fspxett8	48	18	in	in	IN
cord-327272-fspxett8	48	19	Wuhan	Wuhan	NNP
cord-327272-fspxett8	48	20	,	,	,
cord-327272-fspxett8	48	21	China	China	NNP
cord-327272-fspxett8	48	22	Potential	Potential	NNP
cord-327272-fspxett8	48	23	for	for	IN
cord-327272-fspxett8	48	24	global	global	JJ
cord-327272-fspxett8	48	25	spread	spread	NN
cord-327272-fspxett8	48	26	of	of	IN
cord-327272-fspxett8	48	27	a	a	DT
cord-327272-fspxett8	48	28	novel	novel	JJ
cord-327272-fspxett8	48	29	coronavirus	coronavirus	NN
cord-327272-fspxett8	48	30	from	from	IN
cord-327272-fspxett8	48	31	China	China	NNP
cord-327272-fspxett8	48	32	2019-nCoV	2019-ncov	CD
cord-327272-fspxett8	48	33	transmission	transmission	NN
cord-327272-fspxett8	48	34	through	through	IN
cord-327272-fspxett8	48	35	the	the	DT
cord-327272-fspxett8	48	36	ocular	ocular	JJ
cord-327272-fspxett8	48	37	surface	surface	NN
cord-327272-fspxett8	48	38	must	must	MD
cord-327272-fspxett8	48	39	not	not	RB
cord-327272-fspxett8	48	40	be	be	VB
cord-327272-fspxett8	48	41	ignored	ignore	VBN
cord-327272-fspxett8	48	42	Consistent	consistent	JJ
cord-327272-fspxett8	48	43	detection	detection	NN
cord-327272-fspxett8	48	44	of	of	IN
cord-327272-fspxett8	48	45	2019	2019	CD
cord-327272-fspxett8	48	46	novel	novel	JJ
cord-327272-fspxett8	48	47	coronavirus	coronavirus	NN
cord-327272-fspxett8	48	48	in	in	IN
cord-327272-fspxett8	48	49	saliva	saliva	NN
cord-327272-fspxett8	48	50	Transmission	transmission	NN
cord-327272-fspxett8	48	51	of	of	IN
cord-327272-fspxett8	48	52	2019-nCoV	2019-ncov	CD
cord-327272-fspxett8	48	53	infection	infection	NN
cord-327272-fspxett8	48	54	from	from	IN
cord-327272-fspxett8	48	55	an	an	DT
cord-327272-fspxett8	48	56	asymptomatic	asymptomatic	JJ
cord-327272-fspxett8	48	57	contact	contact	NN
cord-327272-fspxett8	48	58	in	in	IN
cord-327272-fspxett8	48	59	Germany	Germany	NNP
cord-327272-fspxett8	48	60	Role	Role	NNP
cord-327272-fspxett8	48	61	of	of	IN
cord-327272-fspxett8	48	62	lopinavir	lopinavir	NNP
cord-327272-fspxett8	48	63	/	/	SYM
cord-327272-fspxett8	48	64	ritonavir	ritonavir	NNS
cord-327272-fspxett8	48	65	in	in	IN
cord-327272-fspxett8	48	66	the	the	DT
cord-327272-fspxett8	48	67	treatment	treatment	NN
cord-327272-fspxett8	48	68	of	of	IN
cord-327272-fspxett8	48	69	SARS	SARS	NNP
cord-327272-fspxett8	48	70	:	:	:
cord-327272-fspxett8	48	71	initial	initial	JJ
cord-327272-fspxett8	48	72	virological	virological	JJ
cord-327272-fspxett8	48	73	and	and	CC
cord-327272-fspxett8	48	74	clinical	clinical	JJ
cord-327272-fspxett8	48	75	findings	finding	NNS
cord-327272-fspxett8	49	1	A	a	DT
cord-327272-fspxett8	49	2	systematic	systematic	JJ
cord-327272-fspxett8	49	3	review	review	NN
cord-327272-fspxett8	49	4	on	on	IN
cord-327272-fspxett8	49	5	the	the	DT
cord-327272-fspxett8	49	6	efficacy	efficacy	NN
cord-327272-fspxett8	49	7	and	and	CC
cord-327272-fspxett8	49	8	safety	safety	NN
cord-327272-fspxett8	49	9	of	of	IN
cord-327272-fspxett8	49	10	chloroquine	chloroquine	NN
cord-327272-fspxett8	49	11	for	for	IN
cord-327272-fspxett8	49	12	the	the	DT
cord-327272-fspxett8	49	13	treatment	treatment	NN
cord-327272-fspxett8	49	14	of	of	IN
cord-327272-fspxett8	49	15	COVID-19	COVID-19	NNP
cord-327272-fspxett8	49	16	Coronavirus	Coronavirus	NNP
cord-327272-fspxett8	49	17	Susceptibility	Susceptibility	NNP
cord-327272-fspxett8	49	18	to	to	IN
cord-327272-fspxett8	49	19	the	the	DT
cord-327272-fspxett8	49	20	Antiviral	Antiviral	NNP
cord-327272-fspxett8	49	21	Remdesivir	Remdesivir	NNP
cord-327272-fspxett8	49	22	(	(	-LRB-
cord-327272-fspxett8	49	23	GS-5734	GS-5734	NNP
cord-327272-fspxett8	49	24	)	)	-RRB-
cord-327272-fspxett8	49	25	Is	be	VBZ
cord-327272-fspxett8	49	26	Mediated	mediate	VBN
cord-327272-fspxett8	49	27	by	by	IN
cord-327272-fspxett8	49	28	the	the	DT
cord-327272-fspxett8	49	29	Viral	Viral	NNP
cord-327272-fspxett8	49	30	Polymerase	Polymerase	NNP
cord-327272-fspxett8	49	31	and	and	CC
cord-327272-fspxett8	49	32	the	the	DT
cord-327272-fspxett8	49	33	Proofreading	proofread	VBG
cord-327272-fspxett8	49	34	Exoribonuclease	Exoribonuclease	NNP
cord-327272-fspxett8	49	35	Challenges	challenge	NNS
cord-327272-fspxett8	49	36	and	and	CC
cord-327272-fspxett8	49	37	opportunities	opportunity	NNS
cord-327272-fspxett8	49	38	with	with	IN
cord-327272-fspxett8	49	39	drug	drug	NN
cord-327272-fspxett8	49	40	repurposing	repurposing	NN
cord-327272-fspxett8	49	41	:	:	:
cord-327272-fspxett8	49	42	finding	find	VBG
cord-327272-fspxett8	49	43	strategies	strategy	NNS
cord-327272-fspxett8	49	44	to	to	TO
cord-327272-fspxett8	49	45	find	find	VB
cord-327272-fspxett8	49	46	alternative	alternative	JJ
cord-327272-fspxett8	49	47	uses	use	NNS
cord-327272-fspxett8	49	48	of	of	IN
cord-327272-fspxett8	49	49	therapeutics	therapeutic	NNS
cord-327272-fspxett8	49	50	A	a	DT
cord-327272-fspxett8	49	51	structure	structure	NN
cord-327272-fspxett8	49	52	-	-	HYPH
cord-327272-fspxett8	49	53	function	function	NN
cord-327272-fspxett8	49	54	diversity	diversity	NN
cord-327272-fspxett8	49	55	survey	survey	NN
cord-327272-fspxett8	49	56	of	of	IN
cord-327272-fspxett8	49	57	the	the	DT
cord-327272-fspxett8	49	58	RNA	RNA	NNP
cord-327272-fspxett8	49	59	-	-	HYPH
cord-327272-fspxett8	49	60	dependent	dependent	JJ
cord-327272-fspxett8	49	61	RNA	RNA	NNP
cord-327272-fspxett8	49	62	polymerases	polymerase	NNS
cord-327272-fspxett8	49	63	from	from	IN
cord-327272-fspxett8	49	64	the	the	DT
cord-327272-fspxett8	49	65	positive	positive	JJ
cord-327272-fspxett8	49	66	-	-	HYPH
cord-327272-fspxett8	49	67	Strand	strand	NN
cord-327272-fspxett8	49	68	RNA	RNA	NNP
cord-327272-fspxett8	49	69	viruses	virus	NNS
cord-327272-fspxett8	49	70	Structural	Structural	NNP
cord-327272-fspxett8	49	71	Analysis	Analysis	NNP
cord-327272-fspxett8	49	72	of	of	IN
cord-327272-fspxett8	49	73	Monomeric	Monomeric	NNP
cord-327272-fspxett8	49	74	RNA	RNA	NNP
cord-327272-fspxett8	49	75	-	-	HYPH
cord-327272-fspxett8	49	76	Dependent	Dependent	NNP
cord-327272-fspxett8	49	77	Polymerases	Polymerases	NNPS
cord-327272-fspxett8	49	78	:	:	:
cord-327272-fspxett8	50	1	Evolutionary	evolutionary	JJ
cord-327272-fspxett8	50	2	and	and	CC
cord-327272-fspxett8	50	3	Therapeutic	Therapeutic	NNP
cord-327272-fspxett8	50	4	Implications	Implications	NNPS
cord-327272-fspxett8	50	5	Identification	Identification	NNP
cord-327272-fspxett8	50	6	of	of	IN
cord-327272-fspxett8	50	7	four	four	CD
cord-327272-fspxett8	50	8	conserved	conserved	JJ
cord-327272-fspxett8	50	9	motifs	motif	NNS
cord-327272-fspxett8	50	10	among	among	IN
cord-327272-fspxett8	50	11	the	the	DT
cord-327272-fspxett8	50	12	RNA	rna	NN
cord-327272-fspxett8	50	13	-	-	HYPH
cord-327272-fspxett8	50	14	dependent	dependent	JJ
cord-327272-fspxett8	50	15	polymerase	polymerase	NN
cord-327272-fspxett8	50	16	encoding	encoding	NN
cord-327272-fspxett8	50	17	elements	element	NNS
cord-327272-fspxett8	50	18	Hepatitis	Hepatitis	NNP
cord-327272-fspxett8	50	19	C	C	NNP
cord-327272-fspxett8	50	20	virus	virus	NN
cord-327272-fspxett8	50	21	therapy	therapy	NN
cord-327272-fspxett8	50	22	:	:	:
cord-327272-fspxett8	50	23	no	no	DT
cord-327272-fspxett8	50	24	one	one	NN
cord-327272-fspxett8	50	25	will	will	MD
cord-327272-fspxett8	50	26	be	be	VB
cord-327272-fspxett8	50	27	left	leave	VBN
cord-327272-fspxett8	50	28	behind	behind	IN
cord-327272-fspxett8	50	29	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	50	30	inhibits	inhibit	VBZ
cord-327272-fspxett8	50	31	yellow	yellow	JJ
cord-327272-fspxett8	50	32	fever	fever	NN
cord-327272-fspxett8	50	33	virus	virus	NN
cord-327272-fspxett8	50	34	in	in	IN
cord-327272-fspxett8	50	35	vitro	vitro	FW
cord-327272-fspxett8	50	36	and	and	CC
cord-327272-fspxett8	50	37	in	in	IN
cord-327272-fspxett8	50	38	patients	patient	NNS
cord-327272-fspxett8	50	39	with	with	IN
cord-327272-fspxett8	50	40	acute	acute	JJ
cord-327272-fspxett8	50	41	liver	liver	NN
cord-327272-fspxett8	50	42	failure	failure	NN
cord-327272-fspxett8	51	1	Sofosbuvir	Sofosbuvir	NNP
cord-327272-fspxett8	51	2	inhibits	inhibit	VBZ
cord-327272-fspxett8	51	3	hepatitis	hepatitis	NNP
cord-327272-fspxett8	51	4	a	a	DT
cord-327272-fspxett8	51	5	virus	virus	NN
cord-327272-fspxett8	51	6	replication	replication	NN
cord-327272-fspxett8	51	7	in	in	IN
cord-327272-fspxett8	51	8	vitro	vitro	FW
cord-327272-fspxett8	51	9	assessed	assess	VBN
cord-327272-fspxett8	51	10	by	by	IN
cord-327272-fspxett8	51	11	a	a	DT
cord-327272-fspxett8	51	12	cell	cell	NN
cord-327272-fspxett8	51	13	-	-	HYPH
cord-327272-fspxett8	51	14	based	base	VBN
cord-327272-fspxett8	51	15	fluorescent	fluorescent	JJ
cord-327272-fspxett8	51	16	reporter	reporter	NN
cord-327272-fspxett8	51	17	system	system	NN
cord-327272-fspxett8	51	18	SARS	SARS	NNP
cord-327272-fspxett8	51	19	-	-	HYPH
cord-327272-fspxett8	51	20	CoV-2	CoV-2	NNP
cord-327272-fspxett8	51	21	RNA	RNA	NNP
cord-327272-fspxett8	51	22	polymerase	polymerase	NN
cord-327272-fspxett8	51	23	as	as	IN
cord-327272-fspxett8	51	24	target	target	NN
cord-327272-fspxett8	51	25	for	for	IN
cord-327272-fspxett8	51	26	antiviral	antiviral	JJ
cord-327272-fspxett8	51	27	therapy	therapy	NN
cord-327272-fspxett8	51	28	Anti	Anti	NNP
cord-327272-fspxett8	51	29	-	-	NNP
cord-327272-fspxett8	51	30	HCV	HCV	NNP
cord-327272-fspxett8	51	31	,	,	,
cord-327272-fspxett8	51	32	nucleotide	nucleotide	JJ
cord-327272-fspxett8	51	33	inhibitors	inhibitor	NNS
cord-327272-fspxett8	51	34	,	,	,
cord-327272-fspxett8	51	35	repurposing	repurpose	VBG
cord-327272-fspxett8	51	36	against	against	IN
cord-327272-fspxett8	51	37	COVID-19	COVID-19	NNP
cord-327272-fspxett8	51	38	Care	Care	NNP
cord-327272-fspxett8	51	39	of	of	IN
cord-327272-fspxett8	51	40	patients	patient	NNS
cord-327272-fspxett8	51	41	with	with	IN
cord-327272-fspxett8	51	42	liver	liver	NN
cord-327272-fspxett8	51	43	disease	disease	NN
cord-327272-fspxett8	51	44	during	during	IN
cord-327272-fspxett8	51	45	the	the	DT
cord-327272-fspxett8	51	46	COVID-19	COVID-19	NNP
cord-327272-fspxett8	51	47	pandemic	pandemic	NN
cord-327272-fspxett8	51	48	:	:	:
cord-327272-fspxett8	51	49	EASL	EASL	NNP
cord-327272-fspxett8	51	50	-	-	HYPH
cord-327272-fspxett8	51	51	ESCMID	ESCMID	NNP
cord-327272-fspxett8	51	52	position	position	NN
cord-327272-fspxett8	51	53	paper	paper	NN
cord-327272-fspxett8	52	1	Publisher	publisher	NN
cord-327272-fspxett8	52	2	's	's	POS
cord-327272-fspxett8	52	3	Note	Note	NNP
cord-327272-fspxett8	52	4	Springer	Springer	NNP
cord-327272-fspxett8	52	5	Nature	Nature	NNP
cord-327272-fspxett8	52	6	remains	remain	VBZ
cord-327272-fspxett8	52	7	neutral	neutral	JJ
cord-327272-fspxett8	52	8	with	with	IN
cord-327272-fspxett8	52	9	regard	regard	NN
cord-327272-fspxett8	52	10	to	to	IN
cord-327272-fspxett8	52	11	jurisdictional	jurisdictional	JJ
cord-327272-fspxett8	52	12	claims	claim	NNS
cord-327272-fspxett8	52	13	in	in	IN
cord-327272-fspxett8	52	14	published	publish	VBN
cord-327272-fspxett8	52	15	maps	map	NNS
cord-327272-fspxett8	52	16	and	and	CC
cord-327272-fspxett8	52	17	institutional	institutional	JJ
cord-327272-fspxett8	52	18	affiliations	affiliation	NNS
cord-327272-fspxett8	53	1	Acknowledgements	acknowledgement	NNS
cord-327272-fspxett8	53	2	N/	N/	NNP
cord-327272-fspxett8	54	1	A	a	DT
cord-327272-fspxett8	54	2	1	1	CD
cord-327272-fspxett8	54	3	Laboratory	Laboratory	NNP
cord-327272-fspxett8	54	4	of	of	IN
cord-327272-fspxett8	54	5	Innovative	Innovative	NNP
cord-327272-fspxett8	54	6	Immunological	Immunological	NNP
cord-327272-fspxett8	54	7	Models	Models	NNPS
cord-327272-fspxett8	54	8	,	,	,
cord-327272-fspxett8	54	9	Istituto	Istituto	NNP
cord-327272-fspxett8	54	10	Nazionale	Nazionale	NNP
cord-327272-fspxett8	54	11	per	per	IN
cord-327272-fspxett8	54	12	lo	lo	NNP
cord-327272-fspxett8	54	13	Studio	Studio	NNP
cord-327272-fspxett8	54	14	e	e	NN
cord-327272-fspxett8	54	15	la	la	NNP
cord-327272-fspxett8	54	16	Cura	Cura	NNP
cord-327272-fspxett8	54	17	dei	dei	NNP
cord-327272-fspxett8	54	18	Tumori	Tumori	NNP
cord-327272-fspxett8	54	19	,	,	,
cord-327272-fspxett8	55	1	"	"	``
cord-327272-fspxett8	55	2	Fondazione	Fondazione	NNP
cord-327272-fspxett8	55	3	Pascale	Pascale	NNP
cord-327272-fspxett8	55	4	"	"	''
cord-327272-fspxett8	56	1	-IRCCS	-irccs	UH
cord-327272-fspxett8	56	2	,	,	,
cord-327272-fspxett8	57	1	Via	via	IN
cord-327272-fspxett8	57	2	Mariano	Mariano	NNP
cord-327272-fspxett8	57	3	Semmola	Semmola	NNP
cord-327272-fspxett8	57	4	,	,	,
cord-327272-fspxett8	57	5	1	1	CD
cord-327272-fspxett8	57	6	,	,	,
cord-327272-fspxett8	57	7	80131	80131	CD
cord-327272-fspxett8	57	8	Naples	Naples	NNP
cord-327272-fspxett8	57	9	,	,	,
cord-327272-fspxett8	57	10	Italy	Italy	NNP
cord-327272-fspxett8	57	11	.	.	.
cord-327272-fspxett8	58	1	2	2	LS
cord-327272-fspxett8	58	2	Laboratory	Laboratory	NNP
cord-327272-fspxett8	58	3	of	of	IN
cord-327272-fspxett8	58	4	Molecular	Molecular	NNP
cord-327272-fspxett8	58	5	Biology	Biology	NNP
cord-327272-fspxett8	58	6	and	and	CC
cord-327272-fspxett8	58	7	Viral	Viral	NNP
cord-327272-fspxett8	58	8	Oncology	Oncology	NNP
cord-327272-fspxett8	58	9	,	,	,
cord-327272-fspxett8	58	10	Istituto	Istituto	NNP
cord-327272-fspxett8	58	11	Nazionale	Nazionale	NNP
cord-327272-fspxett8	58	12	per	per	IN
cord-327272-fspxett8	58	13	lo	lo	NNP
cord-327272-fspxett8	58	14	Studio	Studio	NNP
cord-327272-fspxett8	58	15	e	e	NN
cord-327272-fspxett8	58	16	la	la	NNP
cord-327272-fspxett8	58	17	Cura	Cura	NNP
cord-327272-fspxett8	58	18	dei	dei	NNP
cord-327272-fspxett8	58	19	Tumori	Tumori	NNP
cord-327272-fspxett8	58	20	,	,	,
cord-327272-fspxett8	58	21	"	"	``
cord-327272-fspxett8	58	22	Fondazione	Fondazione	NNP
cord-327272-fspxett8	58	23	Pascale	Pascale	NNP
cord-327272-fspxett8	58	24	"	"	''
cord-327272-fspxett8	58	25	-IRCCS	-IRCCS	NNP
cord-327272-fspxett8	58	26	,	,	,
cord-327272-fspxett8	59	1	Via	via	IN
cord-327272-fspxett8	59	2	Mariano	Mariano	NNP
cord-327272-fspxett8	59	3	Semmola	Semmola	NNP
cord-327272-fspxett8	59	4	52	52	CD
cord-327272-fspxett8	59	5	,	,	,
cord-327272-fspxett8	59	6	80131	80131	CD
cord-327272-fspxett8	59	7	Naples	Naples	NNP
cord-327272-fspxett8	59	8	,	,	,
cord-327272-fspxett8	59	9	Italy	Italy	NNP
cord-327272-fspxett8	59	10	.	.	.
cord-327272-fspxett8	60	1	Received	receive	VBN
cord-327272-fspxett8	60	2	:	:	:
cord-327272-fspxett8	61	1	1	1	CD
cord-327272-fspxett8	61	2	May	May	NNP
cord-327272-fspxett8	61	3	2020	2020	CD
cord-327272-fspxett8	61	4	Accepted	accept	VBN
cord-327272-fspxett8	61	5	:	:	:
cord-327272-fspxett8	61	6	5	5	CD
cord-327272-fspxett8	62	1	May	May	NNP
cord-327272-fspxett8	62	2	2020	2020	CD
cord-327272-fspxett8	63	1	Authors	author	NNS
cord-327272-fspxett8	63	2	'	'	POS
cord-327272-fspxett8	63	3	contributions	contribution	NNS
cord-327272-fspxett8	63	4	LB	LB	NNP
cord-327272-fspxett8	63	5	conceived	conceive	VBD
cord-327272-fspxett8	63	6	the	the	DT
cord-327272-fspxett8	63	7	concept	concept	NN
cord-327272-fspxett8	63	8	;	;	:
cord-327272-fspxett8	63	9	FMB	FMB	NNP
cord-327272-fspxett8	63	10	contributed	contribute	VBD
cord-327272-fspxett8	63	11	to	to	IN
cord-327272-fspxett8	63	12	the	the	DT
cord-327272-fspxett8	63	13	concept	concept	NN
cord-327272-fspxett8	63	14	;	;	:
cord-327272-fspxett8	63	15	LB	LB	NNP
cord-327272-fspxett8	63	16	drafted	draft	VBD
cord-327272-fspxett8	63	17	the	the	DT
cord-327272-fspxett8	63	18	manuscript	manuscript	NN
cord-327272-fspxett8	63	19	;	;	:
cord-327272-fspxett8	63	20	LB	LB	NNP
cord-327272-fspxett8	63	21	and	and	CC
cord-327272-fspxett8	63	22	FMB	FMB	NNP
cord-327272-fspxett8	63	23	revised	revise	VBD
cord-327272-fspxett8	63	24	the	the	DT
cord-327272-fspxett8	63	25	manuscript	manuscript	NN
cord-327272-fspxett8	63	26	.	.	.
cord-327272-fspxett8	64	1	The	the	DT
cord-327272-fspxett8	64	2	author(s	author(s	NNP
cord-327272-fspxett8	64	3	)	)	-RRB-
cord-327272-fspxett8	64	4	read	read	VBD
cord-327272-fspxett8	64	5	and	and	CC
cord-327272-fspxett8	64	6	approved	approve	VBD
cord-327272-fspxett8	64	7	the	the	DT
cord-327272-fspxett8	64	8	final	final	JJ
cord-327272-fspxett8	64	9	manuscript	manuscript	NN
cord-327272-fspxett8	64	10	.	.	.
cord-327272-fspxett8	64	11	 	 	_SP
cord-327272-fspxett8	65	1	Ethics	ethic	NNS
cord-327272-fspxett8	65	2	approval	approval	NN
cord-327272-fspxett8	65	3	and	and	CC
cord-327272-fspxett8	65	4	consent	consent	NN
cord-327272-fspxett8	65	5	to	to	TO
cord-327272-fspxett8	65	6	participate	participate	VB
cord-327272-fspxett8	65	7	N/	N/	NNP
cord-327272-fspxett8	66	1	A	a	DT
cord-327272-fspxett8	66	2	Authors	author	NNS
cord-327272-fspxett8	66	3	declare	declare	VBP
cord-327272-fspxett8	66	4	the	the	DT
cord-327272-fspxett8	66	5	absence	absence	NN
cord-327272-fspxett8	66	6	of	of	IN
cord-327272-fspxett8	66	7	any	any	DT
cord-327272-fspxett8	66	8	competing	compete	VBG
cord-327272-fspxett8	66	9	interest	interest	NN
cord-327272-fspxett8	66	10	.	.	.