id	sid	tid	token	lemma	pos
cord-334123-wb45ww7f	1	1	key	key	NN
cord-334123-wb45ww7f	1	2	:	:	:
cord-334123-wb45ww7f	1	3	cord-334123-wb45ww7f	cord-334123-wb45ww7f	NNP
cord-334123-wb45ww7f	1	4	authors	author	NNS
cord-334123-wb45ww7f	1	5	:	:	:
cord-334123-wb45ww7f	1	6	Schimmel	Schimmel	NNP
cord-334123-wb45ww7f	1	7	,	,	,
cord-334123-wb45ww7f	1	8	Paul	Paul	NNP
cord-334123-wb45ww7f	1	9	title	title	NN
cord-334123-wb45ww7f	1	10	:	:	:
cord-334123-wb45ww7f	1	11	RNA	RNA	NNP
cord-334123-wb45ww7f	1	12	pseudoknots	pseudoknot	NNS
cord-334123-wb45ww7f	1	13	that	that	WDT
cord-334123-wb45ww7f	1	14	interact	interact	VBP
cord-334123-wb45ww7f	1	15	with	with	IN
cord-334123-wb45ww7f	1	16	components	component	NNS
cord-334123-wb45ww7f	1	17	of	of	IN
cord-334123-wb45ww7f	1	18	the	the	DT
cord-334123-wb45ww7f	1	19	translation	translation	NN
cord-334123-wb45ww7f	1	20	apparatus	apparatus	NN
cord-334123-wb45ww7f	1	21	date	date	NN
cord-334123-wb45ww7f	1	22	:	:	:
cord-334123-wb45ww7f	2	1	1989	1989	CD
cord-334123-wb45ww7f	2	2	-	-	HYPH
cord-334123-wb45ww7f	2	3	07	07	CD
cord-334123-wb45ww7f	2	4	-	-	SYM
cord-334123-wb45ww7f	2	5	14	14	CD
cord-334123-wb45ww7f	2	6	journal	journal	NN
cord-334123-wb45ww7f	2	7	:	:	:
cord-334123-wb45ww7f	3	1	Cell	cell	NN
cord-334123-wb45ww7f	3	2	DOI	doi	NN
cord-334123-wb45ww7f	3	3	:	:	:
cord-334123-wb45ww7f	3	4	10.1016/0092	10.1016/0092	CD
cord-334123-wb45ww7f	3	5	-	-	HYPH
cord-334123-wb45ww7f	3	6	8674(89)90395	8674(89)90395	CD
cord-334123-wb45ww7f	3	7	-	-	HYPH
cord-334123-wb45ww7f	3	8	4	4	CD
cord-334123-wb45ww7f	3	9	sha	sha	NNP
cord-334123-wb45ww7f	3	10	:	:	:
cord-334123-wb45ww7f	3	11	4b6db8301abc74e155757a72ccd0fcc317131e2a	4b6db8301abc74e155757a72ccd0fcc317131e2a	CD
cord-334123-wb45ww7f	3	12	doc_id	doc_id	CD
cord-334123-wb45ww7f	3	13	:	:	:
cord-334123-wb45ww7f	3	14	334123	334123	CD
cord-334123-wb45ww7f	3	15	cord_uid	cord_uid	NNS
cord-334123-wb45ww7f	3	16	:	:	:
cord-334123-wb45ww7f	4	1	wb45ww7f	wb45ww7f	NNP
cord-334123-wb45ww7f	4	2	nan	nan	NNP
cord-334123-wb45ww7f	5	1	It	-PRON-	PRP
cord-334123-wb45ww7f	5	2	is	be	VBZ
cord-334123-wb45ww7f	5	3	not	not	RB
cord-334123-wb45ww7f	5	4	a	a	DT
cord-334123-wb45ww7f	5	5	long	long	JJ
cord-334123-wb45ww7f	5	6	extrapolation	extrapolation	NN
cord-334123-wb45ww7f	5	7	to	to	TO
cord-334123-wb45ww7f	5	8	recognize	recognize	VB
cord-334123-wb45ww7f	5	9	that	that	IN
cord-334123-wb45ww7f	5	10	the	the	DT
cord-334123-wb45ww7f	5	11	unanticipated	unanticipated	JJ
cord-334123-wb45ww7f	5	12	structural	structural	JJ
cord-334123-wb45ww7f	5	13	motifs	motif	NNS
cord-334123-wb45ww7f	5	14	that	that	WDT
cord-334123-wb45ww7f	5	15	were	be	VBD
cord-334123-wb45ww7f	5	16	found	find	VBN
cord-334123-wb45ww7f	5	17	in	in	IN
cord-334123-wb45ww7f	5	18	tRNA	tRNA	NNP
cord-334123-wb45ww7f	5	19	are	be	VBP
cord-334123-wb45ww7f	5	20	underpinnings	underpinning	NNS
cord-334123-wb45ww7f	5	21	of	of	IN
cord-334123-wb45ww7f	5	22	the	the	DT
cord-334123-wb45ww7f	5	23	RNA	RNA	NNP
cord-334123-wb45ww7f	5	24	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	5	25	.	.	.
cord-334123-wb45ww7f	6	1	The	the	DT
cord-334123-wb45ww7f	6	2	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	6	3	was	be	VBD
cord-334123-wb45ww7f	6	4	proposed	propose	VBN
cord-334123-wb45ww7f	6	5	as	as	IN
cord-334123-wb45ww7f	6	6	a	a	DT
cord-334123-wb45ww7f	6	7	potentially	potentially	RB
cord-334123-wb45ww7f	6	8	widespread	widespread	JJ
cord-334123-wb45ww7f	6	9	motif	motif	NN
cord-334123-wb45ww7f	6	10	by	by	IN
cord-334123-wb45ww7f	6	11	Pleij	Pleij	NNP
cord-334123-wb45ww7f	6	12	et	et	NNP
cord-334123-wb45ww7f	6	13	al	al	NNP
cord-334123-wb45ww7f	6	14	.	.	.
cord-334123-wb45ww7f	7	1	(	(	-LRB-
cord-334123-wb45ww7f	7	2	1985	1985	CD
cord-334123-wb45ww7f	7	3	)	)	-RRB-
cord-334123-wb45ww7f	7	4	and	and	CC
cord-334123-wb45ww7f	7	5	several	several	JJ
cord-334123-wb45ww7f	7	6	pieces	piece	NNS
cord-334123-wb45ww7f	7	7	of	of	IN
cord-334123-wb45ww7f	7	8	experimental	experimental	JJ
cord-334123-wb45ww7f	7	9	data	datum	NNS
cord-334123-wb45ww7f	7	10	are	be	VBP
cord-334123-wb45ww7f	7	11	consistent	consistent	JJ
cord-334123-wb45ww7f	7	12	with	with	IN
cord-334123-wb45ww7f	7	13	its	-PRON-	PRP$
cord-334123-wb45ww7f	7	14	presence	presence	NN
cord-334123-wb45ww7f	7	15	in	in	IN
cord-334123-wb45ww7f	7	16	some	some	DT
cord-334123-wb45ww7f	7	17	messenger	messenger	NN
cord-334123-wb45ww7f	7	18	,	,	,
cord-334123-wb45ww7f	7	19	ribosomal	ribosomal	NN
cord-334123-wb45ww7f	7	20	,	,	,
cord-334123-wb45ww7f	7	21	and	and	CC
cord-334123-wb45ww7f	7	22	viral	viral	JJ
cord-334123-wb45ww7f	7	23	RNAs	rna	NNS
cord-334123-wb45ww7f	7	24	(	(	-LRB-
cord-334123-wb45ww7f	7	25	see	see	VBP
cord-334123-wb45ww7f	7	26	also	also	RB
cord-334123-wb45ww7f	7	27	Rietveld	Rietveld	NNP
cord-334123-wb45ww7f	7	28	et	et	FW
cord-334123-wb45ww7f	7	29	al	al	NNP
cord-334123-wb45ww7f	7	30	.	.	NNP
cord-334123-wb45ww7f	7	31	,	,	,
cord-334123-wb45ww7f	7	32	1983	1983	CD
cord-334123-wb45ww7f	7	33	)	)	-RRB-
cord-334123-wb45ww7f	7	34	.	.	.
cord-334123-wb45ww7f	8	1	The	the	DT
cord-334123-wb45ww7f	8	2	present	present	JJ
cord-334123-wb45ww7f	8	3	programs	program	NNS
cord-334123-wb45ww7f	8	4	for	for	IN
cord-334123-wb45ww7f	8	5	energy	energy	NN
cord-334123-wb45ww7f	8	6	minimization	minimization	NN
cord-334123-wb45ww7f	8	7	of	of	IN
cord-334123-wb45ww7f	8	8	predicted	predict	VBN
cord-334123-wb45ww7f	8	9	secondary	secondary	JJ
cord-334123-wb45ww7f	8	10	structures	structure	NNS
cord-334123-wb45ww7f	8	11	exclude	exclude	VBP
cord-334123-wb45ww7f	8	12	the	the	DT
cord-334123-wb45ww7f	8	13	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	8	14	motif	motif	NN
cord-334123-wb45ww7f	8	15	(	(	-LRB-
cord-334123-wb45ww7f	8	16	Zucker	Zucker	NNP
cord-334123-wb45ww7f	8	17	,	,	,
cord-334123-wb45ww7f	8	18	1989	1989	CD
cord-334123-wb45ww7f	8	19	)	)	-RRB-
cord-334123-wb45ww7f	8	20	but	but	CC
cord-334123-wb45ww7f	8	21	once	once	IN
cord-334123-wb45ww7f	8	22	it	-PRON-	PRP
cord-334123-wb45ww7f	8	23	was	be	VBD
cord-334123-wb45ww7f	8	24	recognized	recognize	VBN
cord-334123-wb45ww7f	8	25	as	as	IN
cord-334123-wb45ww7f	8	26	at	at	IN
cord-334123-wb45ww7f	8	27	least	least	JJS
cord-334123-wb45ww7f	8	28	a	a	DT
cord-334123-wb45ww7f	8	29	formal	formal	JJ
cord-334123-wb45ww7f	8	30	possibility	possibility	NN
cord-334123-wb45ww7f	8	31	,	,	,
cord-334123-wb45ww7f	8	32	examples	example	NNS
cord-334123-wb45ww7f	8	33	began	begin	VBD
cord-334123-wb45ww7f	8	34	to	to	TO
cord-334123-wb45ww7f	8	35	appear	appear	VB
cord-334123-wb45ww7f	8	36	.	.	.
cord-334123-wb45ww7f	9	1	Most	most	RBS
cord-334123-wb45ww7f	9	2	recently	recently	RB
cord-334123-wb45ww7f	9	3	,	,	,
cord-334123-wb45ww7f	9	4	two	two	CD
cord-334123-wb45ww7f	9	5	papers	paper	NNS
cord-334123-wb45ww7f	9	6	describe	describe	VBP
cord-334123-wb45ww7f	9	7	experiments	experiment	NNS
cord-334123-wb45ww7f	9	8	that	that	IN
cord-334123-wb45ww7f	9	9	not	not	RB
cord-334123-wb45ww7f	9	10	only	only	RB
cord-334123-wb45ww7f	9	11	support	support	VBP
cord-334123-wb45ww7f	9	12	the	the	DT
cord-334123-wb45ww7f	9	13	presence	presence	NN
cord-334123-wb45ww7f	9	14	of	of	IN
cord-334123-wb45ww7f	9	15	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	9	16	structures	structure	NNS
cord-334123-wb45ww7f	9	17	in	in	IN
cord-334123-wb45ww7f	9	18	different	different	JJ
cord-334123-wb45ww7f	9	19	mRNAs	mrna	NNS
cord-334123-wb45ww7f	9	20	,	,	,
cord-334123-wb45ww7f	9	21	but	but	CC
cord-334123-wb45ww7f	9	22	also	also	RB
cord-334123-wb45ww7f	9	23	give	give	VBP
cord-334123-wb45ww7f	9	24	evidence	evidence	NN
cord-334123-wb45ww7f	9	25	that	that	IN
cord-334123-wb45ww7f	9	26	these	these	DT
cord-334123-wb45ww7f	9	27	structures	structure	NNS
cord-334123-wb45ww7f	9	28	are	be	VBP
cord-334123-wb45ww7f	9	29	specifically	specifically	RB
cord-334123-wb45ww7f	9	30	recognized	recognize	VBN
cord-334123-wb45ww7f	9	31	by	by	IN
cord-334123-wb45ww7f	9	32	components	component	NNS
cord-334123-wb45ww7f	9	33	of	of	IN
cord-334123-wb45ww7f	9	34	the	the	DT
cord-334123-wb45ww7f	9	35	translation	translation	NN
cord-334123-wb45ww7f	9	36	apparatus	apparatus	NN
cord-334123-wb45ww7f	9	37	(	(	-LRB-
cord-334123-wb45ww7f	9	38	Tang	Tang	NNP
cord-334123-wb45ww7f	9	39	and	and	CC
cord-334123-wb45ww7f	9	40	Draper	Draper	NNP
cord-334123-wb45ww7f	9	41	,	,	,
cord-334123-wb45ww7f	9	42	1989	1989	CD
cord-334123-wb45ww7f	9	43	;	;	:
cord-334123-wb45ww7f	9	44	Brierley	Brierley	NNP
cord-334123-wb45ww7f	9	45	et	et	NNP
cord-334123-wb45ww7f	9	46	al	al	NNP
cord-334123-wb45ww7f	9	47	.	.	NNP
cord-334123-wb45ww7f	9	48	,	,	,
cord-334123-wb45ww7f	9	49	1989	1989	CD
cord-334123-wb45ww7f	9	50	)	)	-RRB-
cord-334123-wb45ww7f	9	51	.	.	.
cord-334123-wb45ww7f	10	1	A	a	DT
cord-334123-wb45ww7f	10	2	third	third	JJ
cord-334123-wb45ww7f	10	3	and	and	CC
cord-334123-wb45ww7f	10	4	earlier	early	JJR
cord-334123-wb45ww7f	10	5	study	study	NN
cord-334123-wb45ww7f	10	6	proposed	propose	VBD
cord-334123-wb45ww7f	10	7	that	that	IN
cord-334123-wb45ww7f	10	8	an	an	DT
cord-334123-wb45ww7f	10	9	RNA	RNA	NNP
cord-334123-wb45ww7f	10	10	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	10	11	is	be	VBZ
cord-334123-wb45ww7f	10	12	recognized	recognize	VBN
cord-334123-wb45ww7f	10	13	by	by	IN
cord-334123-wb45ww7f	10	14	a	a	DT
cord-334123-wb45ww7f	10	15	DNA	dna	NN
cord-334123-wb45ww7f	10	16	binding	binding	NN
cord-334123-wb45ww7f	10	17	protein	protein	NN
cord-334123-wb45ww7f	10	18	that	that	WDT
cord-334123-wb45ww7f	10	19	autogenously	autogenously	NNP
cord-334123-wb45ww7f	10	20	regulates	regulate	VBZ
cord-334123-wb45ww7f	10	21	translation	translation	NN
cord-334123-wb45ww7f	10	22	of	of	IN
cord-334123-wb45ww7f	10	23	its	-PRON-	PRP$
cord-334123-wb45ww7f	10	24	mRNA	mRNA	NNP
cord-334123-wb45ww7f	10	25	(	(	-LRB-
cord-334123-wb45ww7f	10	26	McPheeters	McPheeters	NNP
cord-334123-wb45ww7f	10	27	et	et	NNP
cord-334123-wb45ww7f	10	28	al	al	NNP
cord-334123-wb45ww7f	10	29	.	.	NNP
cord-334123-wb45ww7f	10	30	,	,	,
cord-334123-wb45ww7f	10	31	1988	1988	CD
cord-334123-wb45ww7f	10	32	)	)	-RRB-
cord-334123-wb45ww7f	10	33	.	.	.
cord-334123-wb45ww7f	11	1	The	the	DT
cord-334123-wb45ww7f	11	2	elucidation	elucidation	NN
cord-334123-wb45ww7f	11	3	of	of	IN
cord-334123-wb45ww7f	11	4	the	the	DT
cord-334123-wb45ww7f	11	5	three	three	CD
cord-334123-wb45ww7f	11	6	-	-	HYPH
cord-334123-wb45ww7f	11	7	dimensional	dimensional	JJ
cord-334123-wb45ww7f	11	8	structure	structure	NN
cord-334123-wb45ww7f	11	9	of	of	IN
cord-334123-wb45ww7f	11	10	tRNA	trna	NN
cord-334123-wb45ww7f	11	11	was	be	VBD
cord-334123-wb45ww7f	11	12	a	a	DT
cord-334123-wb45ww7f	11	13	benchmark	benchmark	NN
cord-334123-wb45ww7f	11	14	because	because	IN
cord-334123-wb45ww7f	11	15	,	,	,
cord-334123-wb45ww7f	11	16	among	among	IN
cord-334123-wb45ww7f	11	17	other	other	JJ
cord-334123-wb45ww7f	11	18	contributions	contribution	NNS
cord-334123-wb45ww7f	11	19	,	,	,
cord-334123-wb45ww7f	11	20	it	-PRON-	PRP
cord-334123-wb45ww7f	11	21	demonstrated	demonstrate	VBD
cord-334123-wb45ww7f	11	22	the	the	DT
cord-334123-wb45ww7f	11	23	complexity	complexity	NN
cord-334123-wb45ww7f	11	24	of	of	IN
cord-334123-wb45ww7f	11	25	molecular	molecular	JJ
cord-334123-wb45ww7f	11	26	form	form	NN
cord-334123-wb45ww7f	11	27	and	and	CC
cord-334123-wb45ww7f	11	28	shape	shape	NN
cord-334123-wb45ww7f	11	29	possible	possible	JJ
cord-334123-wb45ww7f	11	30	with	with	IN
cord-334123-wb45ww7f	11	31	RNA	RNA	NNP
cord-334123-wb45ww7f	11	32	molecules	molecule	NNS
cord-334123-wb45ww7f	11	33	.	.	.
cord-334123-wb45ww7f	12	1	As	as	IN
cord-334123-wb45ww7f	12	2	anticipated	anticipate	VBN
cord-334123-wb45ww7f	12	3	,	,	,
cord-334123-wb45ww7f	12	4	it	-PRON-	PRP
cord-334123-wb45ww7f	12	5	confirmed	confirm	VBD
cord-334123-wb45ww7f	12	6	the	the	DT
cord-334123-wb45ww7f	12	7	pattern	pattern	NN
cord-334123-wb45ww7f	12	8	of	of	IN
cord-334123-wb45ww7f	12	9	hydrogen	hydrogen	NN
cord-334123-wb45ww7f	12	10	bonds	bond	NNS
cord-334123-wb45ww7f	12	11	in	in	IN
cord-334123-wb45ww7f	12	12	the	the	DT
cord-334123-wb45ww7f	12	13	cloverleaf	cloverleaf	JJ
cord-334123-wb45ww7f	12	14	secondary	secondary	JJ
cord-334123-wb45ww7f	12	15	structure	structure	NN
cord-334123-wb45ww7f	12	16	that	that	WDT
cord-334123-wb45ww7f	12	17	was	be	VBD
cord-334123-wb45ww7f	12	18	predicted	predict	VBN
cord-334123-wb45ww7f	12	19	from	from	IN
cord-334123-wb45ww7f	12	20	the	the	DT
cord-334123-wb45ww7f	12	21	sequence	sequence	NN
cord-334123-wb45ww7f	12	22	.	.	.
cord-334123-wb45ww7f	13	1	Unexpectedly	unexpectedly	RB
cord-334123-wb45ww7f	13	2	,	,	,
cord-334123-wb45ww7f	13	3	it	-PRON-	PRP
cord-334123-wb45ww7f	13	4	also	also	RB
cord-334123-wb45ww7f	13	5	revealed	reveal	VBD
cord-334123-wb45ww7f	13	6	that	that	IN
cord-334123-wb45ww7f	13	7	the	the	DT
cord-334123-wb45ww7f	13	8	singlestranded	singlestranded	JJ
cord-334123-wb45ww7f	13	9	loops	loop	NNS
cord-334123-wb45ww7f	13	10	in	in	IN
cord-334123-wb45ww7f	13	11	the	the	DT
cord-334123-wb45ww7f	13	12	proposed	propose	VBN
cord-334123-wb45ww7f	13	13	cloverleaf	cloverleaf	NN
cord-334123-wb45ww7f	13	14	secondary	secondary	JJ
cord-334123-wb45ww7f	13	15	structure	structure	NN
cord-334123-wb45ww7f	13	16	are	be	VBP
cord-334123-wb45ww7f	13	17	not	not	RB
cord-334123-wb45ww7f	13	18	passive	passive	JJ
cord-334123-wb45ww7f	13	19	elements	element	NNS
cord-334123-wb45ww7f	13	20	.	.	.
cord-334123-wb45ww7f	14	1	Instead	instead	RB
cord-334123-wb45ww7f	14	2	,	,	,
cord-334123-wb45ww7f	14	3	they	-PRON-	PRP
cord-334123-wb45ww7f	14	4	bear	bear	VBP
cord-334123-wb45ww7f	14	5	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	14	6	that	that	WDT
cord-334123-wb45ww7f	14	7	are	be	VBP
cord-334123-wb45ww7f	14	8	sites	site	NNS
cord-334123-wb45ww7f	14	9	for	for	IN
cord-334123-wb45ww7f	14	10	the	the	DT
cord-334123-wb45ww7f	14	11	sophisticated	sophisticated	JJ
cord-334123-wb45ww7f	14	12	interactions	interaction	NNS
cord-334123-wb45ww7f	14	13	that	that	WDT
cord-334123-wb45ww7f	14	14	stabilize	stabilize	VBP
cord-334123-wb45ww7f	14	15	the	the	DT
cord-334123-wb45ww7f	14	16	highly	highly	RB
cord-334123-wb45ww7f	14	17	differentiated	differentiated	JJ
cord-334123-wb45ww7f	14	18	tertiary	tertiary	JJ
cord-334123-wb45ww7f	14	19	structure	structure	NN
cord-334123-wb45ww7f	14	20	.	.	.
cord-334123-wb45ww7f	15	1	These	these	DT
cord-334123-wb45ww7f	15	2	interactions	interaction	NNS
cord-334123-wb45ww7f	15	3	include	include	VBP
cord-334123-wb45ww7f	15	4	hydrogen	hydrogen	NN
cord-334123-wb45ww7f	15	5	bonds	bond	NNS
cord-334123-wb45ww7f	15	6	that	that	WDT
cord-334123-wb45ww7f	15	7	connect	connect	VBP
cord-334123-wb45ww7f	15	8	the	the	DT
cord-334123-wb45ww7f	15	9	dihydrouridine	dihydrouridine	JJ
cord-334123-wb45ww7f	15	10	loop	loop	NN
cord-334123-wb45ww7f	15	11	to	to	IN
cord-334123-wb45ww7f	15	12	the	the	DT
cord-334123-wb45ww7f	15	13	T$	T$	NNP
cord-334123-wb45ww7f	15	14	and	and	CC
cord-334123-wb45ww7f	15	15	variable	variable	JJ
cord-334123-wb45ww7f	15	16	loops	loop	NNS
cord-334123-wb45ww7f	15	17	.	.	.
cord-334123-wb45ww7f	16	1	The	the	DT
cord-334123-wb45ww7f	16	2	structure	structure	NN
cord-334123-wb45ww7f	16	3	also	also	RB
cord-334123-wb45ww7f	16	4	revealed	reveal	VBD
cord-334123-wb45ww7f	16	5	that	that	IN
cord-334123-wb45ww7f	16	6	the	the	DT
cord-334123-wb45ww7f	16	7	four	four	CD
cord-334123-wb45ww7f	16	8	helical	helical	JJ
cord-334123-wb45ww7f	16	9	stems	stem	NNS
cord-334123-wb45ww7f	16	10	of	of	IN
cord-334123-wb45ww7f	16	11	the	the	DT
cord-334123-wb45ww7f	16	12	cloverleaf	cloverleaf	NN
cord-334123-wb45ww7f	16	13	are	be	VBP
cord-334123-wb45ww7f	16	14	stacked	stack	VBN
cord-334123-wb45ww7f	16	15	in	in	IN
cord-334123-wb45ww7f	16	16	pairs	pair	NNS
cord-334123-wb45ww7f	16	17	to	to	TO
cord-334123-wb45ww7f	16	18	form	form	VB
cord-334123-wb45ww7f	16	19	two	two	CD
cord-334123-wb45ww7f	16	20	longer	long	JJR
cord-334123-wb45ww7f	16	21	,	,	,
cord-334123-wb45ww7f	16	22	continuous	continuous	JJ
cord-334123-wb45ww7f	16	23	helices	helix	NNS
cord-334123-wb45ww7f	16	24	which	which	WDT
cord-334123-wb45ww7f	16	25	are	be	VBP
cord-334123-wb45ww7f	16	26	arranged	arrange	VBN
cord-334123-wb45ww7f	16	27	at	at	IN
cord-334123-wb45ww7f	16	28	approximately	approximately	RB
cord-334123-wb45ww7f	16	29	right	right	JJ
cord-334123-wb45ww7f	16	30	angles	angle	NNS
cord-334123-wb45ww7f	16	31	to	to	TO
cord-334123-wb45ww7f	16	32	form	form	VB
cord-334123-wb45ww7f	16	33	an	an	DT
cord-334123-wb45ww7f	16	34	L	l	NN
cord-334123-wb45ww7f	16	35	-	-	HYPH
cord-334123-wb45ww7f	16	36	shaped	shape	VBN
cord-334123-wb45ww7f	16	37	molecule	molecule	NN
cord-334123-wb45ww7f	16	38	.	.	.
cord-334123-wb45ww7f	17	1	Pseudoknots	pseudoknot	NNS
cord-334123-wb45ww7f	17	2	are	be	VBP
cord-334123-wb45ww7f	17	3	formed	form	VBN
cord-334123-wb45ww7f	17	4	from	from	IN
cord-334123-wb45ww7f	17	5	stem	stem	NN
cord-334123-wb45ww7f	17	6	-	-	HYPH
cord-334123-wb45ww7f	17	7	loop	loop	NN
cord-334123-wb45ww7f	17	8	structures	structure	NNS
cord-334123-wb45ww7f	17	9	in	in	IN
cord-334123-wb45ww7f	17	10	which	which	WDT
cord-334123-wb45ww7f	17	11	bases	basis	NNS
cord-334123-wb45ww7f	17	12	outside	outside	RB
cord-334123-wb45ww7f	17	13	of	of	IN
cord-334123-wb45ww7f	17	14	a	a	DT
cord-334123-wb45ww7f	17	15	stem	stem	NN
cord-334123-wb45ww7f	17	16	-	-	HYPH
cord-334123-wb45ww7f	17	17	loop	loop	NN
cord-334123-wb45ww7f	17	18	are	be	VBP
cord-334123-wb45ww7f	17	19	paired	pair	VBN
cord-334123-wb45ww7f	17	20	with	with	IN
cord-334123-wb45ww7f	17	21	those	those	DT
cord-334123-wb45ww7f	17	22	in	in	IN
cord-334123-wb45ww7f	17	23	the	the	DT
cord-334123-wb45ww7f	17	24	loop	loop	NN
cord-334123-wb45ww7f	17	25	so	so	IN
cord-334123-wb45ww7f	17	26	as	as	IN
cord-334123-wb45ww7f	17	27	to	to	TO
cord-334123-wb45ww7f	17	28	create	create	VB
cord-334123-wb45ww7f	17	29	a	a	DT
cord-334123-wb45ww7f	17	30	second	second	JJ
cord-334123-wb45ww7f	17	31	stem	stem	NN
cord-334123-wb45ww7f	17	32	(	(	-LRB-
cord-334123-wb45ww7f	17	33	Figure	figure	NN
cord-334123-wb45ww7f	17	34	1A	1a	NN
cord-334123-wb45ww7f	17	35	)	)	-RRB-
cord-334123-wb45ww7f	17	36	.	.	.
cord-334123-wb45ww7f	18	1	The	the	DT
cord-334123-wb45ww7f	18	2	second	second	JJ
cord-334123-wb45ww7f	18	3	stem	stem	NN
cord-334123-wb45ww7f	18	4	can	can	MD
cord-334123-wb45ww7f	18	5	be	be	VB
cord-334123-wb45ww7f	18	6	stacked	stack	VBN
cord-334123-wb45ww7f	18	7	upon	upon	IN
cord-334123-wb45ww7f	18	8	the	the	DT
cord-334123-wb45ww7f	18	9	first	first	JJ
cord-334123-wb45ww7f	18	10	to	to	TO
cord-334123-wb45ww7f	18	11	form	form	VB
cord-334123-wb45ww7f	18	12	a	a	DT
cord-334123-wb45ww7f	18	13	continuous	continuous	JJ
cord-334123-wb45ww7f	18	14	coaxial	coaxial	JJ
cord-334123-wb45ww7f	18	15	helix	helix	NN
cord-334123-wb45ww7f	18	16	.	.	.
cord-334123-wb45ww7f	19	1	Thus	thus	RB
cord-334123-wb45ww7f	19	2	,	,	,
cord-334123-wb45ww7f	19	3	the	the	DT
cord-334123-wb45ww7f	19	4	hydrogen	hydrogen	NN
cord-334123-wb45ww7f	19	5	-	-	HYPH
cord-334123-wb45ww7f	19	6	bonded	bond	VBN
cord-334123-wb45ww7f	19	7	articulation	articulation	NN
cord-334123-wb45ww7f	19	8	of	of	IN
cord-334123-wb45ww7f	19	9	bases	basis	NNS
cord-334123-wb45ww7f	19	10	in	in	IN
cord-334123-wb45ww7f	19	11	a	a	DT
cord-334123-wb45ww7f	19	12	loop	loop	NN
cord-334123-wb45ww7f	19	13	with	with	IN
cord-334123-wb45ww7f	19	14	bases	basis	NNS
cord-334123-wb45ww7f	19	15	in	in	IN
cord-334123-wb45ww7f	19	16	another	another	DT
cord-334123-wb45ww7f	19	17	part	part	NN
cord-334123-wb45ww7f	19	18	of	of	IN
cord-334123-wb45ww7f	19	19	the	the	DT
cord-334123-wb45ww7f	19	20	RNA	RNA	NNP
cord-334123-wb45ww7f	19	21	,	,	,
cord-334123-wb45ww7f	19	22	and	and	CC
cord-334123-wb45ww7f	19	23	the	the	DT
cord-334123-wb45ww7f	19	24	coaxial	coaxial	JJ
cord-334123-wb45ww7f	19	25	stacking	stacking	NN
cord-334123-wb45ww7f	19	26	of	of	IN
cord-334123-wb45ww7f	19	27	short	short	JJ
cord-334123-wb45ww7f	19	28	helical	helical	JJ
cord-334123-wb45ww7f	19	29	stems	stem	NNS
cord-334123-wb45ww7f	19	30	to	to	TO
cord-334123-wb45ww7f	19	31	form	form	VB
cord-334123-wb45ww7f	19	32	a	a	DT
cord-334123-wb45ww7f	19	33	single	single	JJ
cord-334123-wb45ww7f	19	34	longer	long	JJR
cord-334123-wb45ww7f	19	35	helix	helix	NN
cord-334123-wb45ww7f	19	36	,	,	,
cord-334123-wb45ww7f	19	37	are	be	VBP
cord-334123-wb45ww7f	19	38	general	general	JJ
cord-334123-wb45ww7f	19	39	themes	theme	NNS
cord-334123-wb45ww7f	19	40	in	in	IN
cord-334123-wb45ww7f	19	41	tRNAs	trna	NNS
cord-334123-wb45ww7f	19	42	that	that	WDT
cord-334123-wb45ww7f	19	43	are	be	VBP
cord-334123-wb45ww7f	19	44	reiterated	reiterate	VBN
cord-334123-wb45ww7f	19	45	in	in	IN
cord-334123-wb45ww7f	19	46	pseudoknots	pseudoknot	NNS
cord-334123-wb45ww7f	19	47	.	.	.
cord-334123-wb45ww7f	20	1	However	however	RB
cord-334123-wb45ww7f	20	2	,	,	,
cord-334123-wb45ww7f	20	3	the	the	DT
cord-334123-wb45ww7f	20	4	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	20	5	has	have	VBZ
cord-334123-wb45ww7f	20	6	an	an	DT
cord-334123-wb45ww7f	20	7	added	add	VBN
cord-334123-wb45ww7f	20	8	complexity	complexity	NN
cord-334123-wb45ww7f	20	9	that	that	WDT
cord-334123-wb45ww7f	20	10	is	be	VBZ
cord-334123-wb45ww7f	20	11	not	not	RB
cord-334123-wb45ww7f	20	12	observed	observe	VBN
cord-334123-wb45ww7f	20	13	in	in	IN
cord-334123-wb45ww7f	20	14	tRNAs	trna	NNS
cord-334123-wb45ww7f	21	1	:	:	:
cord-334123-wb45ww7f	21	2	the	the	DT
cord-334123-wb45ww7f	21	3	coaxial	coaxial	JJ
cord-334123-wb45ww7f	21	4	stacking	stacking	NN
cord-334123-wb45ww7f	21	5	of	of	IN
cord-334123-wb45ww7f	21	6	helices	helix	NNS
cord-334123-wb45ww7f	21	7	requires	require	VBZ
cord-334123-wb45ww7f	21	8	that	that	IN
cord-334123-wb45ww7f	21	9	singlestranded	singlestrande	VBN
cord-334123-wb45ww7f	21	10	connecting	connect	VBG
cord-334123-wb45ww7f	21	11	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	21	12	cross	cross	VBP
cord-334123-wb45ww7f	21	13	the	the	DT
cord-334123-wb45ww7f	21	14	grooves	groove	NNS
cord-334123-wb45ww7f	21	15	of	of	IN
cord-334123-wb45ww7f	21	16	the	the	DT
cord-334123-wb45ww7f	21	17	RNA	RNA	NNP
cord-334123-wb45ww7f	21	18	double	double	JJ
cord-334123-wb45ww7f	21	19	helix	helix	NN
cord-334123-wb45ww7f	21	20	(	(	-LRB-
cord-334123-wb45ww7f	21	21	Figure	figure	NN
cord-334123-wb45ww7f	21	22	1B	1b	CD
cord-334123-wb45ww7f	21	23	)	)	-RRB-
cord-334123-wb45ww7f	21	24	.	.	.
cord-334123-wb45ww7f	22	1	From	from	IN
cord-334123-wb45ww7f	22	2	a	a	DT
cord-334123-wb45ww7f	22	3	three	three	CD
cord-334123-wb45ww7f	22	4	-	-	HYPH
cord-334123-wb45ww7f	22	5	dimensional	dimensional	JJ
cord-334123-wb45ww7f	22	6	model	model	NN
cord-334123-wb45ww7f	22	7	it	-PRON-	PRP
cord-334123-wb45ww7f	22	8	is	be	VBZ
cord-334123-wb45ww7f	22	9	clear	clear	JJ
cord-334123-wb45ww7f	22	10	that	that	IN
cord-334123-wb45ww7f	22	11	one	one	CD
cord-334123-wb45ww7f	22	12	crossing	crossing	NN
cord-334123-wb45ww7f	22	13	,	,	,
cord-334123-wb45ww7f	22	14	over	over	IN
cord-334123-wb45ww7f	22	15	the	the	DT
cord-334123-wb45ww7f	22	16	deep	deep	JJ
cord-334123-wb45ww7f	22	17	groove	groove	NN
cord-334123-wb45ww7f	22	18	,	,	,
cord-334123-wb45ww7f	22	19	can	can	MD
cord-334123-wb45ww7f	22	20	be	be	VB
cord-334123-wb45ww7f	22	21	accomplished	accomplish	VBN
cord-334123-wb45ww7f	22	22	with	with	IN
cord-334123-wb45ww7f	22	23	two	two	CD
cord-334123-wb45ww7f	22	24	nucleotide	nucleotide	JJ
cord-334123-wb45ww7f	22	25	units	unit	NNS
cord-334123-wb45ww7f	22	26	.	.	.
cord-334123-wb45ww7f	23	1	The	the	DT
cord-334123-wb45ww7f	23	2	other	other	JJ
cord-334123-wb45ww7f	23	3	crossing	crossing	NN
cord-334123-wb45ww7f	23	4	,	,	,
cord-334123-wb45ww7f	23	5	over	over	IN
cord-334123-wb45ww7f	23	6	the	the	DT
cord-334123-wb45ww7f	23	7	shallow	shallow	JJ
cord-334123-wb45ww7f	23	8	groove	groove	NN
cord-334123-wb45ww7f	23	9	,	,	,
cord-334123-wb45ww7f	23	10	requires	require	VBZ
cord-334123-wb45ww7f	23	11	(	(	-LRB-
cord-334123-wb45ww7f	23	12	for	for	IN
cord-334123-wb45ww7f	23	13	a	a	DT
cord-334123-wb45ww7f	23	14	bridge	bridge	NN
cord-334123-wb45ww7f	23	15	of	of	IN
cord-334123-wb45ww7f	23	16	two	two	CD
cord-334123-wb45ww7f	23	17	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	23	18	)	)	-RRB-
cord-334123-wb45ww7f	23	19	a	a	DT
cord-334123-wb45ww7f	23	20	perturbation	perturbation	NN
cord-334123-wb45ww7f	23	21	of	of	IN
cord-334123-wb45ww7f	23	22	the	the	DT
cord-334123-wb45ww7f	23	23	normal	normal	JJ
cord-334123-wb45ww7f	23	24	helical	helical	NN
cord-334123-wb45ww7f	23	25	and	and	CC
cord-334123-wb45ww7f	23	26	,	,	,
cord-334123-wb45ww7f	23	27	additionally	additionally	RB
cord-334123-wb45ww7f	23	28	or	or	CC
cord-334123-wb45ww7f	23	29	alternatively	alternatively	RB
cord-334123-wb45ww7f	23	30	,	,	,
cord-334123-wb45ww7f	23	31	bridging	bridge	VBG
cord-334123-wb45ww7f	23	32	mononucleotide	mononucleotide	NN
cord-334123-wb45ww7f	23	33	conformational	conformational	JJ
cord-334123-wb45ww7f	23	34	parameters	parameter	NNS
cord-334123-wb45ww7f	23	35	.	.	.
cord-334123-wb45ww7f	24	1	Tinoco	Tinoco	NNP
cord-334123-wb45ww7f	24	2	's	's	POS
cord-334123-wb45ww7f	24	3	laboratory	laboratory	NN
cord-334123-wb45ww7f	24	4	has	have	VBZ
cord-334123-wb45ww7f	24	5	done	do	VBN
cord-334123-wb45ww7f	24	6	a	a	DT
cord-334123-wb45ww7f	24	7	careful	careful	JJ
cord-334123-wb45ww7f	24	8	analytical	analytical	JJ
cord-334123-wb45ww7f	24	9	study	study	NN
cord-334123-wb45ww7f	24	10	of	of	IN
cord-334123-wb45ww7f	24	11	the	the	DT
cord-334123-wb45ww7f	24	12	structure	structure	NN
cord-334123-wb45ww7f	24	13	and	and	CC
cord-334123-wb45ww7f	24	14	thermodynamic	thermodynamic	JJ
cord-334123-wb45ww7f	24	15	properties	property	NNS
cord-334123-wb45ww7f	24	16	in	in	IN
cord-334123-wb45ww7f	24	17	solution	solution	NN
cord-334123-wb45ww7f	24	18	of	of	IN
cord-334123-wb45ww7f	24	19	a	a	DT
cord-334123-wb45ww7f	24	20	nonadecanucleotide	nonadecanucleotide	NN
cord-334123-wb45ww7f	24	21	that	that	WDT
cord-334123-wb45ww7f	24	22	has	have	VBZ
cord-334123-wb45ww7f	24	23	the	the	DT
cord-334123-wb45ww7f	24	24	potential	potential	NN
cord-334123-wb45ww7f	24	25	to	to	TO
cord-334123-wb45ww7f	24	26	form	form	VB
cord-334123-wb45ww7f	24	27	a	a	DT
cord-334123-wb45ww7f	24	28	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	24	29	in	in	IN
cord-334123-wb45ww7f	24	30	which	which	WDT
cord-334123-wb45ww7f	24	31	stems	stem	VBZ
cord-334123-wb45ww7f	24	32	of	of	IN
cord-334123-wb45ww7f	24	33	3	3	CD
cord-334123-wb45ww7f	24	34	and	and	CC
cord-334123-wb45ww7f	24	35	4	4	CD
cord-334123-wb45ww7f	24	36	bp	bp	NNP
cord-334123-wb45ww7f	24	37	combine	combine	VBP
cord-334123-wb45ww7f	24	38	to	to	TO
cord-334123-wb45ww7f	24	39	make	make	VB
cord-334123-wb45ww7f	24	40	a	a	DT
cord-334123-wb45ww7f	24	41	7	7	CD
cord-334123-wb45ww7f	24	42	bp	bp	NNP
cord-334123-wb45ww7f	24	43	helix	helix	NN
cord-334123-wb45ww7f	25	1	(	(	-LRB-
cord-334123-wb45ww7f	25	2	Puglisi	Puglisi	NNP
cord-334123-wb45ww7f	25	3	et	et	NNP
cord-334123-wb45ww7f	25	4	al	al	NNP
cord-334123-wb45ww7f	25	5	.	.	NNP
cord-334123-wb45ww7f	25	6	,	,	,
cord-334123-wb45ww7f	25	7	1988	1988	CD
cord-334123-wb45ww7f	25	8	)	)	-RRB-
cord-334123-wb45ww7f	25	9	.	.	.
cord-334123-wb45ww7f	26	1	In	in	IN
cord-334123-wb45ww7f	26	2	the	the	DT
cord-334123-wb45ww7f	26	3	proposed	propose	VBN
cord-334123-wb45ww7f	26	4	structure	structure	NN
cord-334123-wb45ww7f	26	5	,	,	,
cord-334123-wb45ww7f	26	6	three	three	CD
cord-334123-wb45ww7f	26	7	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	26	8	bridge	bridge	VBP
cord-334123-wb45ww7f	26	9	across	across	IN
cord-334123-wb45ww7f	26	10	the	the	DT
cord-334123-wb45ww7f	26	11	major	major	JJ
cord-334123-wb45ww7f	26	12	groove	groove	NN
cord-334123-wb45ww7f	26	13	and	and	CC
cord-334123-wb45ww7f	26	14	two	two	CD
cord-334123-wb45ww7f	26	15	are	be	VBP
cord-334123-wb45ww7f	26	16	used	use	VBN
cord-334123-wb45ww7f	26	17	to	to	TO
cord-334123-wb45ww7f	26	18	cross	cross	VB
cord-334123-wb45ww7f	26	19	the	the	DT
cord-334123-wb45ww7f	26	20	minor	minor	JJ
cord-334123-wb45ww7f	26	21	groove	groove	NN
cord-334123-wb45ww7f	26	22	.	.	.
cord-334123-wb45ww7f	27	1	Strong	strong	JJ
cord-334123-wb45ww7f	27	2	evidence	evidence	NN
cord-334123-wb45ww7f	27	3	for	for	IN
cord-334123-wb45ww7f	27	4	the	the	DT
cord-334123-wb45ww7f	27	5	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	27	6	structure	structure	NN
cord-334123-wb45ww7f	27	7	was	be	VBD
cord-334123-wb45ww7f	27	8	obtained	obtain	VBN
cord-334123-wb45ww7f	27	9	.	.	.
cord-334123-wb45ww7f	28	1	The	the	DT
cord-334123-wb45ww7f	28	2	thermodynamic	thermodynamic	JJ
cord-334123-wb45ww7f	28	3	stabilities	stability	NNS
cord-334123-wb45ww7f	28	4	and	and	CC
cord-334123-wb45ww7f	28	5	hypochromicities	hypochromicitie	NNS
cord-334123-wb45ww7f	28	6	of	of	IN
cord-334123-wb45ww7f	28	7	the	the	DT
cord-334123-wb45ww7f	28	8	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	28	9	,	,	,
cord-334123-wb45ww7f	28	10	of	of	IN
cord-334123-wb45ww7f	28	11	a	a	DT
cord-334123-wb45ww7f	28	12	sequence	sequence	NN
cord-334123-wb45ww7f	28	13	variant	variant	NN
cord-334123-wb45ww7f	28	14	that	that	WDT
cord-334123-wb45ww7f	28	15	could	could	MD
cord-334123-wb45ww7f	28	16	not	not	RB
cord-334123-wb45ww7f	28	17	form	form	VB
cord-334123-wb45ww7f	28	18	one	one	CD
cord-334123-wb45ww7f	28	19	of	of	IN
cord-334123-wb45ww7f	28	20	the	the	DT
cord-334123-wb45ww7f	28	21	stems	stem	NNS
cord-334123-wb45ww7f	28	22	of	of	IN
cord-334123-wb45ww7f	28	23	the	the	DT
cord-334123-wb45ww7f	28	24	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	28	25	,	,	,
cord-334123-wb45ww7f	28	26	and	and	CC
cord-334123-wb45ww7f	28	27	of	of	IN
cord-334123-wb45ww7f	28	28	the	the	DT
cord-334123-wb45ww7f	28	29	individual	individual	NN
cord-334123-wb45ww7f	28	30	stems	stem	NNS
cord-334123-wb45ww7f	28	31	were	be	VBD
cord-334123-wb45ww7f	28	32	investigated	investigate	VBN
cord-334123-wb45ww7f	28	33	.	.	.
cord-334123-wb45ww7f	29	1	These	these	DT
cord-334123-wb45ww7f	29	2	data	datum	NNS
cord-334123-wb45ww7f	29	3	showed	show	VBD
cord-334123-wb45ww7f	29	4	that	that	IN
cord-334123-wb45ww7f	29	5	the	the	DT
cord-334123-wb45ww7f	29	6	stacking	stacking	NN
cord-334123-wb45ww7f	29	7	enthalpy	enthalpy	NN
cord-334123-wb45ww7f	29	8	was	be	VBD
cord-334123-wb45ww7f	29	9	higher	high	JJR
cord-334123-wb45ww7f	29	10	for	for	IN
cord-334123-wb45ww7f	29	11	the	the	DT
cord-334123-wb45ww7f	29	12	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	29	13	than	than	IN
cord-334123-wb45ww7f	29	14	for	for	IN
cord-334123-wb45ww7f	29	15	the	the	DT
cord-334123-wb45ww7f	29	16	molecules	molecule	NNS
cord-334123-wb45ww7f	29	17	that	that	WDT
cord-334123-wb45ww7f	29	18	contained	contain	VBD
cord-334123-wb45ww7f	29	19	the	the	DT
cord-334123-wb45ww7f	29	20	individual	individual	NN
cord-334123-wb45ww7f	29	21	stems	stem	VBZ
cord-334123-wb45ww7f	29	22	,	,	,
cord-334123-wb45ww7f	29	23	although	although	IN
cord-334123-wb45ww7f	29	24	not	not	RB
cord-334123-wb45ww7f	29	25	as	as	RB
cord-334123-wb45ww7f	29	26	high	high	JJ
cord-334123-wb45ww7f	29	27	as	as	IN
cord-334123-wb45ww7f	29	28	expected	expect	VBN
cord-334123-wb45ww7f	29	29	for	for	IN
cord-334123-wb45ww7f	29	30	a	a	DT
cord-334123-wb45ww7f	29	31	structure	structure	NN
cord-334123-wb45ww7f	29	32	with	with	IN
cord-334123-wb45ww7f	29	33	seven	seven	CD
cord-334123-wb45ww7f	29	34	contiguous	contiguous	JJ
cord-334123-wb45ww7f	29	35	base	base	NN
cord-334123-wb45ww7f	29	36	pairs	pair	NNS
cord-334123-wb45ww7f	29	37	.	.	.
cord-334123-wb45ww7f	30	1	This	this	DT
cord-334123-wb45ww7f	30	2	observation	observation	NN
cord-334123-wb45ww7f	30	3	and	and	CC
cord-334123-wb45ww7f	30	4	the	the	DT
cord-334123-wb45ww7f	30	5	reduced	reduce	VBN
cord-334123-wb45ww7f	30	6	hypochromicity	hypochromicity	NN
cord-334123-wb45ww7f	30	7	of	of	IN
cord-334123-wb45ww7f	30	8	the	the	DT
cord-334123-wb45ww7f	30	9	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	30	10	suggest	suggest	VBP
cord-334123-wb45ww7f	30	11	a	a	DT
cord-334123-wb45ww7f	30	12	distortion	distortion	NN
cord-334123-wb45ww7f	30	13	in	in	IN
cord-334123-wb45ww7f	30	14	stem	stem	NN
cord-334123-wb45ww7f	30	15	and	and	CC
cord-334123-wb45ww7f	30	16	loop	loop	NN
cord-334123-wb45ww7f	30	17	portions	portion	NNS
cord-334123-wb45ww7f	30	18	which	which	WDT
cord-334123-wb45ww7f	30	19	could	could	MD
cord-334123-wb45ww7f	30	20	be	be	VB
cord-334123-wb45ww7f	30	21	caused	cause	VBN
cord-334123-wb45ww7f	30	22	by	by	IN
cord-334123-wb45ww7f	30	23	the	the	DT
cord-334123-wb45ww7f	30	24	presumed	presume	VBN
cord-334123-wb45ww7f	30	25	two	two	CD
cord-334123-wb45ww7f	30	26	-	-	HYPH
cord-334123-wb45ww7f	30	27	base	base	NN
cord-334123-wb45ww7f	30	28	crossing	crossing	NN
cord-334123-wb45ww7f	30	29	of	of	IN
cord-334123-wb45ww7f	30	30	the	the	DT
cord-334123-wb45ww7f	30	31	minor	minor	JJ
cord-334123-wb45ww7f	30	32	groove	groove	NN
cord-334123-wb45ww7f	30	33	.	.	.
cord-334123-wb45ww7f	31	1	As	as	IN
cord-334123-wb45ww7f	31	2	presented	present	VBN
cord-334123-wb45ww7f	31	3	by	by	IN
cord-334123-wb45ww7f	31	4	Pleij	Pleij	NNP
cord-334123-wb45ww7f	31	5	et	et	NNP
cord-334123-wb45ww7f	31	6	al	al	NNP
cord-334123-wb45ww7f	31	7	.	.	.
cord-334123-wb45ww7f	32	1	(	(	-LRB-
cord-334123-wb45ww7f	32	2	1985	1985	CD
cord-334123-wb45ww7f	32	3	)	)	-RRB-
cord-334123-wb45ww7f	33	1	the	the	DT
cord-334123-wb45ww7f	33	2	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	33	3	proposal	proposal	NN
cord-334123-wb45ww7f	33	4	developed	develop	VBN
cord-334123-wb45ww7f	33	5	from	from	IN
cord-334123-wb45ww7f	33	6	structural	structural	JJ
cord-334123-wb45ww7f	33	7	mapping	mapping	NN
cord-334123-wb45ww7f	33	8	and	and	CC
cord-334123-wb45ww7f	33	9	modeling	modeling	NN
cord-334123-wb45ww7f	33	10	of	of	IN
cord-334123-wb45ww7f	33	11	the	the	DT
cord-334123-wb45ww7f	33	12	3	3	CD
cord-334123-wb45ww7f	33	13	'	'	NN
cord-334123-wb45ww7f	33	14	end	end	NN
cord-334123-wb45ww7f	33	15	of	of	IN
cord-334123-wb45ww7f	33	16	plant	plant	NN
cord-334123-wb45ww7f	33	17	viral	viral	JJ
cord-334123-wb45ww7f	33	18	RNAs	rna	NNS
cord-334123-wb45ww7f	33	19	that	that	WDT
cord-334123-wb45ww7f	33	20	have	have	VBP
cord-334123-wb45ww7f	33	21	tRNA	trna	NN
cord-334123-wb45ww7f	33	22	-	-	HYPH
cord-334123-wb45ww7f	33	23	like	like	JJ
cord-334123-wb45ww7f	33	24	properties	property	NNS
cord-334123-wb45ww7f	33	25	.	.	.
cord-334123-wb45ww7f	34	1	Thus	thus	RB
cord-334123-wb45ww7f	34	2	,	,	,
cord-334123-wb45ww7f	34	3	tobacco	tobacco	NN
cord-334123-wb45ww7f	34	4	mosaic	mosaic	NNP
cord-334123-wb45ww7f	34	5	virus	virus	NN
cord-334123-wb45ww7f	34	6	RNA	RNA	NNP
cord-334123-wb45ww7f	34	7	,	,	,
cord-334123-wb45ww7f	34	8	turnip	turnip	NN
cord-334123-wb45ww7f	34	9	yellow	yellow	JJ
cord-334123-wb45ww7f	34	10	mosaic	mosaic	NNP
cord-334123-wb45ww7f	34	11	virus	virus	NN
cord-334123-wb45ww7f	34	12	(	(	-LRB-
cord-334123-wb45ww7f	34	13	TYMV	TYMV	NNP
cord-334123-wb45ww7f	34	14	)	)	-RRB-
cord-334123-wb45ww7f	34	15	,	,	,
cord-334123-wb45ww7f	34	16	and	and	CC
cord-334123-wb45ww7f	34	17	brome	brome	NNP
cord-334123-wb45ww7f	34	18	mosaic	mosaic	NNP
cord-334123-wb45ww7f	34	19	virus	virus	NN
cord-334123-wb45ww7f	34	20	RNAs	rna	NNS
cord-334123-wb45ww7f	34	21	are	be	VBP
cord-334123-wb45ww7f	34	22	aminoacylated	aminoacylate	VBN
cord-334123-wb45ww7f	34	23	specifically	specifically	RB
cord-334123-wb45ww7f	34	24	with	with	IN
cord-334123-wb45ww7f	34	25	histidine	histidine	NN
cord-334123-wb45ww7f	34	26	,	,	,
cord-334123-wb45ww7f	34	27	valine	valine	NN
cord-334123-wb45ww7f	34	28	,	,	,
cord-334123-wb45ww7f	34	29	and	and	CC
cord-334123-wb45ww7f	34	30	tyrosine	tyrosine	NN
cord-334123-wb45ww7f	34	31	,	,	,
cord-334123-wb45ww7f	34	32	respectively	respectively	RB
cord-334123-wb45ww7f	34	33	,	,	,
cord-334123-wb45ww7f	34	34	and	and	CC
cord-334123-wb45ww7f	34	35	each	each	DT
cord-334123-wb45ww7f	34	36	is	be	VBZ
cord-334123-wb45ww7f	34	37	recognized	recognize	VBN
cord-334123-wb45ww7f	34	38	by	by	IN
cord-334123-wb45ww7f	34	39	the	the	DT
cord-334123-wb45ww7f	34	40	tRNA	tRNA	NNP
cord-334123-wb45ww7f	34	41	nucleotidyl	nucleotidyl	NNP
cord-334123-wb45ww7f	34	42	transferase	transferase	NNP
cord-334123-wb45ww7f	34	43	,	,	,
cord-334123-wb45ww7f	34	44	which	which	WDT
cord-334123-wb45ww7f	34	45	adds	add	VBZ
cord-334123-wb45ww7f	34	46	the	the	DT
cord-334123-wb45ww7f	34	47	CCA	CCA	NNP
cord-334123-wb45ww7f	34	48	sequence	sequence	NN
cord-334123-wb45ww7f	34	49	at	at	IN
cord-334123-wb45ww7f	34	50	the	the	DT
cord-334123-wb45ww7f	34	51	3'terminus	3'terminus	CD
cord-334123-wb45ww7f	34	52	of	of	IN
cord-334123-wb45ww7f	34	53	all	all	DT
cord-334123-wb45ww7f	34	54	tRNA	tRNA	NNP
cord-334123-wb45ww7f	34	55	molecules	molecule	NNS
cord-334123-wb45ww7f	34	56	(	(	-LRB-
cord-334123-wb45ww7f	34	57	reviewed	review	VBN
cord-334123-wb45ww7f	34	58	in	in	IN
cord-334123-wb45ww7f	34	59	Haenni	Haenni	NNP
cord-334123-wb45ww7f	34	60	et	et	NNP
cord-334123-wb45ww7f	34	61	al	al	NNP
cord-334123-wb45ww7f	34	62	.	.	NNP
cord-334123-wb45ww7f	34	63	,	,	,
cord-334123-wb45ww7f	34	64	1982	1982	CD
cord-334123-wb45ww7f	34	65	)	)	-RRB-
cord-334123-wb45ww7f	34	66	.	.	.
cord-334123-wb45ww7f	35	1	Figure	figure	NN
cord-334123-wb45ww7f	35	2	2A	2a	CD
cord-334123-wb45ww7f	35	3	shows	show	VBZ
cord-334123-wb45ww7f	35	4	how	how	WRB
cord-334123-wb45ww7f	35	5	the	the	DT
cord-334123-wb45ww7f	35	6	four	four	CD
cord-334123-wb45ww7f	35	7	stems	stem	NNS
cord-334123-wb45ww7f	35	8	of	of	IN
cord-334123-wb45ww7f	35	9	the	the	DT
cord-334123-wb45ww7f	35	10	tRNA	tRNA	NNP
cord-334123-wb45ww7f	35	11	cloverleaf	cloverleaf	NN
cord-334123-wb45ww7f	35	12	are	be	VBP
cord-334123-wb45ww7f	35	13	combined	combine	VBN
cord-334123-wb45ww7f	35	14	into	into	IN
cord-334123-wb45ww7f	35	15	two	two	CD
cord-334123-wb45ww7f	35	16	continuous	continuous	JJ
cord-334123-wb45ww7f	35	17	helices	helix	NNS
cord-334123-wb45ww7f	35	18	that	that	WDT
cord-334123-wb45ww7f	35	19	constitute	constitute	VBP
cord-334123-wb45ww7f	35	20	the	the	DT
cord-334123-wb45ww7f	35	21	two	two	CD
cord-334123-wb45ww7f	35	22	arms	arm	NNS
cord-334123-wb45ww7f	35	23	of	of	IN
cord-334123-wb45ww7f	35	24	the	the	DT
cord-334123-wb45ww7f	35	25	L	l	NN
cord-334123-wb45ww7f	35	26	-	-	HYPH
cord-334123-wb45ww7f	35	27	shaped	shape	VBN
cord-334123-wb45ww7f	35	28	three	three	CD
cord-334123-wb45ww7f	35	29	-	-	HYPH
cord-334123-wb45ww7f	35	30	dimensional	dimensional	JJ
cord-334123-wb45ww7f	35	31	structure	structure	NN
cord-334123-wb45ww7f	35	32	.	.	.
cord-334123-wb45ww7f	36	1	The	the	DT
cord-334123-wb45ww7f	36	2	acceptor	acceptor	NN
cord-334123-wb45ww7f	36	3	-	-	HYPH
cord-334123-wb45ww7f	36	4	T6	T6	NNP
cord-334123-wb45ww7f	36	5	stems	stem	VBZ
cord-334123-wb45ww7f	36	6	form	form	VBP
cord-334123-wb45ww7f	36	7	one	one	CD
cord-334123-wb45ww7f	36	8	continuous	continuous	JJ
cord-334123-wb45ww7f	36	9	minihelix	minihelix	NNS
cord-334123-wb45ww7f	36	10	of	of	IN
cord-334123-wb45ww7f	36	11	12	12	CD
cord-334123-wb45ww7f	36	12	bp	bp	NNP
cord-334123-wb45ww7f	36	13	.	.	.
cord-334123-wb45ww7f	37	1	Seven	seven	CD
cord-334123-wb45ww7f	37	2	of	of	IN
cord-334123-wb45ww7f	37	3	these	these	DT
cord-334123-wb45ww7f	37	4	pairs	pair	NNS
cord-334123-wb45ww7f	37	5	are	be	VBP
cord-334123-wb45ww7f	37	6	derived	derive	VBN
cord-334123-wb45ww7f	37	7	from	from	IN
cord-334123-wb45ww7f	37	8	the	the	DT
cord-334123-wb45ww7f	37	9	acceptor	acceptor	NN
cord-334123-wb45ww7f	37	10	and	and	CC
cord-334123-wb45ww7f	37	11	five	five	CD
cord-334123-wb45ww7f	37	12	from	from	IN
cord-334123-wb45ww7f	37	13	the	the	DT
cord-334123-wb45ww7f	37	14	TI$	TI$	NNP
cord-334123-wb45ww7f	37	15	helix	helix	NN
cord-334123-wb45ww7f	37	16	.	.	.
cord-334123-wb45ww7f	38	1	The	the	DT
cord-334123-wb45ww7f	38	2	problem	problem	NN
cord-334123-wb45ww7f	38	3	is	be	VBZ
cord-334123-wb45ww7f	38	4	how	how	WRB
cord-334123-wb45ww7f	38	5	to	to	TO
cord-334123-wb45ww7f	38	6	form	form	VB
cord-334123-wb45ww7f	38	7	an	an	DT
cord-334123-wb45ww7f	38	8	equivalent	equivalent	JJ
cord-334123-wb45ww7f	38	9	minihelix	minihelix	NN
cord-334123-wb45ww7f	38	10	from	from	IN
cord-334123-wb45ww7f	38	11	sequences	sequence	NNS
cord-334123-wb45ww7f	38	12	,	,	,
cord-334123-wb45ww7f	38	13	for	for	IN
cord-334123-wb45ww7f	38	14	example	example	NN
cord-334123-wb45ww7f	38	15	,	,	,
cord-334123-wb45ww7f	38	16	at	at	IN
cord-334123-wb45ww7f	38	17	the	the	DT
cord-334123-wb45ww7f	38	18	3'terminus	3'terminus	CD
cord-334123-wb45ww7f	38	19	of	of	IN
cord-334123-wb45ww7f	38	20	TYMV	TYMV	NNP
cord-334123-wb45ww7f	38	21	RNA	RNA	NNP
cord-334123-wb45ww7f	38	22	.	.	.
cord-334123-wb45ww7f	39	1	A	a	DT
cord-334123-wb45ww7f	39	2	conventional	conventional	JJ
cord-334123-wb45ww7f	39	3	secondary	secondary	JJ
cord-334123-wb45ww7f	39	4	structure	structure	NN
cord-334123-wb45ww7f	39	5	analysis	analysis	NN
cord-334123-wb45ww7f	39	6	suggested	suggest	VBD
cord-334123-wb45ww7f	39	7	that	that	IN
cord-334123-wb45ww7f	39	8	this	this	DT
cord-334123-wb45ww7f	39	9	segment	segment	NN
cord-334123-wb45ww7f	39	10	encodes	encode	VBZ
cord-334123-wb45ww7f	39	11	two	two	CD
cord-334123-wb45ww7f	39	12	stem	stem	NN
cord-334123-wb45ww7f	39	13	-	-	HYPH
cord-334123-wb45ww7f	39	14	loop	loop	NN
cord-334123-wb45ww7f	39	15	segments	segment	NNS
cord-334123-wb45ww7f	39	16	with	with	IN
cord-334123-wb45ww7f	39	17	5	5	CD
cord-334123-wb45ww7f	39	18	and	and	CC
cord-334123-wb45ww7f	39	19	4	4	CD
cord-334123-wb45ww7f	39	20	bp	bp	NNP
cord-334123-wb45ww7f	39	21	,	,	,
cord-334123-wb45ww7f	39	22	respectively	respectively	RB
cord-334123-wb45ww7f	39	23	.	.	.
cord-334123-wb45ww7f	40	1	However	however	RB
cord-334123-wb45ww7f	40	2	,	,	,
cord-334123-wb45ww7f	40	3	by	by	IN
cord-334123-wb45ww7f	40	4	implementation	implementation	NN
cord-334123-wb45ww7f	40	5	of	of	IN
cord-334123-wb45ww7f	40	6	the	the	DT
cord-334123-wb45ww7f	40	7	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	40	8	format	format	NN
cord-334123-wb45ww7f	40	9	,	,	,
cord-334123-wb45ww7f	40	10	the	the	DT
cord-334123-wb45ww7f	40	11	desired	desire	VBN
cord-334123-wb45ww7f	40	12	12	12	CD
cord-334123-wb45ww7f	40	13	bp	bp	NNP
cord-334123-wb45ww7f	40	14	minihelix	minihelix	NNP
cord-334123-wb45ww7f	40	15	can	can	MD
cord-334123-wb45ww7f	40	16	be	be	VB
cord-334123-wb45ww7f	40	17	constructed	construct	VBN
cord-334123-wb45ww7f	40	18	(	(	-LRB-
cord-334123-wb45ww7f	40	19	Figure	Figure	NNP
cord-334123-wb45ww7f	40	20	28	28	CD
cord-334123-wb45ww7f	40	21	)	)	-RRB-
cord-334123-wb45ww7f	40	22	and	and	CC
cord-334123-wb45ww7f	40	23	combined	combine	VBN
cord-334123-wb45ww7f	40	24	with	with	IN
cord-334123-wb45ww7f	40	25	adjoining	adjoin	VBG
cord-334123-wb45ww7f	40	26	sequences	sequence	NNS
cord-334123-wb45ww7f	40	27	to	to	TO
cord-334123-wb45ww7f	40	28	form	form	VB
cord-334123-wb45ww7f	40	29	a	a	DT
cord-334123-wb45ww7f	40	30	tRNA	trna	NN
cord-334123-wb45ww7f	40	31	-	-	HYPH
cord-334123-wb45ww7f	40	32	like	like	JJ
cord-334123-wb45ww7f	40	33	structure	structure	NN
cord-334123-wb45ww7f	40	34	(	(	-LRB-
cord-334123-wb45ww7f	40	35	not	not	RB
cord-334123-wb45ww7f	40	36	shown	show	VBN
cord-334123-wb45ww7f	40	37	)	)	-RRB-
cord-334123-wb45ww7f	40	38	.	.	.
cord-334123-wb45ww7f	41	1	Whether	whether	IN
cord-334123-wb45ww7f	41	2	the	the	DT
cord-334123-wb45ww7f	41	3	minihelix	minihelix	NNP
cord-334123-wb45ww7f	41	4	format	format	NN
cord-334123-wb45ww7f	41	5	is	be	VBZ
cord-334123-wb45ww7f	41	6	sufficient	sufficient	JJ
cord-334123-wb45ww7f	41	7	for	for	IN
cord-334123-wb45ww7f	41	8	aminoacylation	aminoacylation	NN
cord-334123-wb45ww7f	41	9	of	of	IN
cord-334123-wb45ww7f	41	10	TYMV	TYMV	NNP
cord-334123-wb45ww7f	41	11	or	or	CC
cord-334123-wb45ww7f	41	12	other	other	JJ
cord-334123-wb45ww7f	41	13	viral	viral	JJ
cord-334123-wb45ww7f	41	14	RNAs	rna	NNS
cord-334123-wb45ww7f	41	15	is	be	VBZ
cord-334123-wb45ww7f	41	16	not	not	RB
cord-334123-wb45ww7f	41	17	known	know	VBN
cord-334123-wb45ww7f	41	18	.	.	.
cord-334123-wb45ww7f	42	1	It	-PRON-	PRP
cord-334123-wb45ww7f	42	2	is	be	VBZ
cord-334123-wb45ww7f	42	3	worth	worth	JJ
cord-334123-wb45ww7f	42	4	noting	note	VBG
cord-334123-wb45ww7f	42	5	that	that	IN
cord-334123-wb45ww7f	42	6	,	,	,
cord-334123-wb45ww7f	42	7	at	at	IN
cord-334123-wb45ww7f	42	8	least	least	JJS
cord-334123-wb45ww7f	42	9	for	for	IN
cord-334123-wb45ww7f	42	10	alanine	alanine	NN
cord-334123-wb45ww7f	42	11	,	,	,
cord-334123-wb45ww7f	42	12	the	the	DT
cord-334123-wb45ww7f	42	13	acceptor	acceptor	NN
cord-334123-wb45ww7f	42	14	-	-	HYPH
cord-334123-wb45ww7f	42	15	T$	T$	NNP
cord-334123-wb45ww7f	42	16	minihelix	minihelix	NNP
cord-334123-wb45ww7f	42	17	and	and	CC
cord-334123-wb45ww7f	42	18	the	the	DT
cord-334123-wb45ww7f	42	19	7	7	CD
cord-334123-wb45ww7f	42	20	bp	bp	NNP
cord-334123-wb45ww7f	42	21	acceptor	acceptor	NN
cord-334123-wb45ww7f	42	22	stem	stem	NN
cord-334123-wb45ww7f	42	23	can	can	MD
cord-334123-wb45ww7f	42	24	be	be	VB
cord-334123-wb45ww7f	42	25	charged	charge	VBN
cord-334123-wb45ww7f	42	26	by	by	IN
cord-334123-wb45ww7f	42	27	the	the	DT
cord-334123-wb45ww7f	42	28	cognate	cognate	JJ
cord-334123-wb45ww7f	42	29	aminoacyl	aminoacyl	NNP
cord-334123-wb45ww7f	42	30	tRNA	tRNA	NNP
cord-334123-wb45ww7f	42	31	synthetase	synthetase	NNP
cord-334123-wb45ww7f	42	32	.	.	.
cord-334123-wb45ww7f	43	1	This	this	DT
cord-334123-wb45ww7f	43	2	is	be	VBZ
cord-334123-wb45ww7f	43	3	because	because	IN
cord-334123-wb45ww7f	43	4	the	the	DT
cord-334123-wb45ww7f	43	5	major	major	JJ
cord-334123-wb45ww7f	43	6	determinant	determinant	NN
cord-334123-wb45ww7f	43	7	for	for	IN
cord-334123-wb45ww7f	43	8	the	the	DT
cord-334123-wb45ww7f	43	9	identity	identity	NN
cord-334123-wb45ww7f	43	10	of	of	IN
cord-334123-wb45ww7f	43	11	an	an	DT
cord-334123-wb45ww7f	43	12	alanine	alanine	NN
cord-334123-wb45ww7f	43	13	tRNA	trna	NN
cord-334123-wb45ww7f	43	14	is	be	VBZ
cord-334123-wb45ww7f	43	15	a	a	DT
cord-334123-wb45ww7f	43	16	single	single	JJ
cord-334123-wb45ww7f	43	17	base	base	NN
cord-334123-wb45ww7f	43	18	pair	pair	NN
cord-334123-wb45ww7f	43	19	that	that	WDT
cord-334123-wb45ww7f	43	20	is	be	VBZ
cord-334123-wb45ww7f	43	21	located	locate	VBN
cord-334123-wb45ww7f	43	22	in	in	IN
cord-334123-wb45ww7f	43	23	the	the	DT
cord-334123-wb45ww7f	43	24	acceptor	acceptor	NN
cord-334123-wb45ww7f	43	25	helix	helix	NN
cord-334123-wb45ww7f	43	26	,	,	,
cord-334123-wb45ww7f	43	27	so	so	IN
cord-334123-wb45ww7f	43	28	that	that	IN
cord-334123-wb45ww7f	43	29	the	the	DT
cord-334123-wb45ww7f	43	30	rest	rest	NN
cord-334123-wb45ww7f	43	31	of	of	IN
cord-334123-wb45ww7f	43	32	the	the	DT
cord-334123-wb45ww7f	43	33	tRNA	tRNA	NNP
cord-334123-wb45ww7f	43	34	structure	structure	NN
cord-334123-wb45ww7f	43	35	is	be	VBZ
cord-334123-wb45ww7f	43	36	dispensable	dispensable	JJ
cord-334123-wb45ww7f	43	37	for	for	IN
cord-334123-wb45ww7f	43	38	aminoacylation	aminoacylation	NN
cord-334123-wb45ww7f	43	39	(	(	-LRB-
cord-334123-wb45ww7f	43	40	Hou	Hou	NNP
cord-334123-wb45ww7f	43	41	and	and	CC
cord-334123-wb45ww7f	43	42	Schimmel	Schimmel	NNP
cord-334123-wb45ww7f	43	43	,	,	,
cord-334123-wb45ww7f	43	44	1988	1988	CD
cord-334123-wb45ww7f	43	45	;	;	:
cord-334123-wb45ww7f	43	46	Francklyn	Francklyn	NNP
cord-334123-wb45ww7f	43	47	and	and	CC
cord-334123-wb45ww7f	43	48	Schimmel	Schimmel	NNP
cord-334123-wb45ww7f	43	49	,	,	,
cord-334123-wb45ww7f	43	50	1989	1989	CD
cord-334123-wb45ww7f	43	51	)	)	-RRB-
cord-334123-wb45ww7f	43	52	.	.	.
cord-334123-wb45ww7f	44	1	The	the	DT
cord-334123-wb45ww7f	44	2	results	result	NNS
cord-334123-wb45ww7f	44	3	with	with	IN
cord-334123-wb45ww7f	44	4	alanine	alanine	NNP
cord-334123-wb45ww7f	44	5	tRNA	tRNA	NNP
cord-334123-wb45ww7f	44	6	raise	raise	VBP
cord-334123-wb45ww7f	44	7	the	the	DT
cord-334123-wb45ww7f	44	8	possibility	possibility	NN
cord-334123-wb45ww7f	44	9	that	that	IN
cord-334123-wb45ww7f	44	10	,	,	,
cord-334123-wb45ww7f	44	11	for	for	IN
cord-334123-wb45ww7f	44	12	at	at	IN
cord-334123-wb45ww7f	44	13	least	least	JJS
cord-334123-wb45ww7f	44	14	some	some	DT
cord-334123-wb45ww7f	44	15	viral	viral	JJ
cord-334123-wb45ww7f	44	16	RNAs	rna	NNS
cord-334123-wb45ww7f	44	17	,	,	,
cord-334123-wb45ww7f	44	18	synthetase	synthetase	NN
cord-334123-wb45ww7f	44	19	recognition	recognition	NN
cord-334123-wb45ww7f	44	20	requires	require	VBZ
cord-334123-wb45ww7f	44	21	only	only	RB
cord-334123-wb45ww7f	44	22	a	a	DT
cord-334123-wb45ww7f	44	23	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	44	24	structure	structure	NN
cord-334123-wb45ww7f	44	25	that	that	WDT
cord-334123-wb45ww7f	44	26	bears	bear	VBZ
cord-334123-wb45ww7f	44	27	resemblance	resemblance	NN
cord-334123-wb45ww7f	44	28	to	to	IN
cord-334123-wb45ww7f	44	29	the	the	DT
cord-334123-wb45ww7f	44	30	3	3	CD
cord-334123-wb45ww7f	44	31	'	'	``
cord-334123-wb45ww7f	44	32	helical	helical	JJ
cord-334123-wb45ww7f	44	33	half	half	NN
cord-334123-wb45ww7f	44	34	(	(	-LRB-
cord-334123-wb45ww7f	44	35	or	or	CC
cord-334123-wb45ww7f	44	36	less	less	JJR
cord-334123-wb45ww7f	44	37	)	)	-RRB-
cord-334123-wb45ww7f	44	38	and	and	CC
cord-334123-wb45ww7f	44	39	not	not	RB
cord-334123-wb45ww7f	44	40	to	to	IN
cord-334123-wb45ww7f	44	41	the	the	DT
cord-334123-wb45ww7f	44	42	entire	entire	JJ
cord-334123-wb45ww7f	44	43	tRNA	trna	NN
cord-334123-wb45ww7f	44	44	.	.	.
cord-334123-wb45ww7f	45	1	The	the	DT
cord-334123-wb45ww7f	45	2	tRNA	trna	NN
cord-334123-wb45ww7f	45	3	-	-	HYPH
cord-334123-wb45ww7f	45	4	like	like	JJ
cord-334123-wb45ww7f	45	5	structures	structure	NNS
cord-334123-wb45ww7f	45	6	at	at	IN
cord-334123-wb45ww7f	45	7	the	the	DT
cord-334123-wb45ww7f	45	8	3	3	CD
cord-334123-wb45ww7f	45	9	'	'	''
cord-334123-wb45ww7f	45	10	ends	end	NNS
cord-334123-wb45ww7f	45	11	of	of	IN
cord-334123-wb45ww7f	45	12	plant	plant	NN
cord-334123-wb45ww7f	45	13	viral	viral	JJ
cord-334123-wb45ww7f	45	14	RNAs	rna	NNS
cord-334123-wb45ww7f	45	15	provide	provide	VBP
cord-334123-wb45ww7f	45	16	one	one	CD
cord-334123-wb45ww7f	45	17	example	example	NN
cord-334123-wb45ww7f	45	18	where	where	WRB
cord-334123-wb45ww7f	45	19	the	the	DT
cord-334123-wb45ww7f	45	20	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	45	21	format	format	NN
cord-334123-wb45ww7f	45	22	may	may	MD
cord-334123-wb45ww7f	45	23	be	be	VB
cord-334123-wb45ww7f	45	24	necessary	necessary	JJ
cord-334123-wb45ww7f	45	25	to	to	TO
cord-334123-wb45ww7f	45	26	form	form	VB
cord-334123-wb45ww7f	45	27	a	a	DT
cord-334123-wb45ww7f	45	28	substrate	substrate	NN
cord-334123-wb45ww7f	45	29	that	that	WDT
cord-334123-wb45ww7f	45	30	is	be	VBZ
cord-334123-wb45ww7f	45	31	specifically	specifically	RB
cord-334123-wb45ww7f	45	32	recognized	recognize	VBN
cord-334123-wb45ww7f	45	33	by	by	IN
cord-334123-wb45ww7f	45	34	an	an	DT
cord-334123-wb45ww7f	45	35	enzyme	enzyme	NN
cord-334123-wb45ww7f	45	36	.	.	.
cord-334123-wb45ww7f	46	1	Dreher	Dreher	NNP
cord-334123-wb45ww7f	46	2	and	and	CC
cord-334123-wb45ww7f	46	3	Hall	Hall	NNP
cord-334123-wb45ww7f	46	4	(	(	-LRB-
cord-334123-wb45ww7f	46	5	1988	1988	CD
cord-334123-wb45ww7f	46	6	)	)	-RRB-
cord-334123-wb45ww7f	46	7	have	have	VBP
cord-334123-wb45ww7f	46	8	shown	show	VBN
cord-334123-wb45ww7f	46	9	that	that	IN
cord-334123-wb45ww7f	46	10	a	a	DT
cord-334123-wb45ww7f	46	11	three	three	CD
cord-334123-wb45ww7f	46	12	base	base	NN
cord-334123-wb45ww7f	46	13	substitution	substitution	NN
cord-334123-wb45ww7f	46	14	that	that	WDT
cord-334123-wb45ww7f	46	15	disrupts	disrupt	VBZ
cord-334123-wb45ww7f	46	16	part	part	NN
cord-334123-wb45ww7f	46	17	of	of	IN
cord-334123-wb45ww7f	46	18	the	the	DT
cord-334123-wb45ww7f	46	19	proposed	propose	VBN
cord-334123-wb45ww7f	46	20	acceptor	acceptor	NN
cord-334123-wb45ww7f	46	21	stem	stem	NN
cord-334123-wb45ww7f	46	22	of	of	IN
cord-334123-wb45ww7f	46	23	brome	brome	NNP
cord-334123-wb45ww7f	46	24	mosaic	mosaic	NNP
cord-334123-wb45ww7f	46	25	virus	virus	NN
cord-334123-wb45ww7f	46	26	RNA	RNA	NNP
cord-334123-wb45ww7f	46	27	simultaneously	simultaneously	RB
cord-334123-wb45ww7f	46	28	impairs	impair	VBZ
cord-334123-wb45ww7f	46	29	aminoacylation	aminoacylation	NN
cord-334123-wb45ww7f	46	30	and	and	CC
cord-334123-wb45ww7f	46	31	nucleotidyl	nucleotidyl	NNP
cord-334123-wb45ww7f	46	32	transferase	transferase	NNP
cord-334123-wb45ww7f	46	33	activities	activity	NNS
cord-334123-wb45ww7f	46	34	.	.	.
cord-334123-wb45ww7f	47	1	To	to	TO
cord-334123-wb45ww7f	47	2	prove	prove	VB
cord-334123-wb45ww7f	47	3	the	the	DT
cord-334123-wb45ww7f	47	4	dependence	dependence	NN
cord-334123-wb45ww7f	47	5	of	of	IN
cord-334123-wb45ww7f	47	6	synthetase	synthetase	NN
cord-334123-wb45ww7f	47	7	recognition	recognition	NN
cord-334123-wb45ww7f	47	8	on	on	IN
cord-334123-wb45ww7f	47	9	the	the	DT
cord-334123-wb45ww7f	47	10	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	47	11	structure	structure	NN
cord-334123-wb45ww7f	47	12	would	would	MD
cord-334123-wb45ww7f	47	13	require	require	VB
cord-334123-wb45ww7f	47	14	evaluation	evaluation	NN
cord-334123-wb45ww7f	47	15	of	of	IN
cord-334123-wb45ww7f	47	16	an	an	DT
cord-334123-wb45ww7f	47	17	ensemble	ensemble	NN
cord-334123-wb45ww7f	47	18	of	of	IN
cord-334123-wb45ww7f	47	19	mutant	mutant	JJ
cord-334123-wb45ww7f	47	20	RNAs	rna	NNS
cord-334123-wb45ww7f	47	21	(	(	-LRB-
cord-334123-wb45ww7f	47	22	cf	cf	XX
cord-334123-wb45ww7f	47	23	.	.	.
cord-334123-wb45ww7f	47	24	Hou	Hou	NNP
cord-334123-wb45ww7f	47	25	and	and	CC
cord-334123-wb45ww7f	47	26	Schimmel	Schimmel	NNP
cord-334123-wb45ww7f	47	27	,	,	,
cord-334123-wb45ww7f	47	28	1988	1988	CD
cord-334123-wb45ww7f	47	29	)	)	-RRB-
cord-334123-wb45ww7f	47	30	.	.	.
cord-334123-wb45ww7f	48	1	These	these	DT
cord-334123-wb45ww7f	48	2	mutants	mutant	NNS
cord-334123-wb45ww7f	48	3	should	should	MD
cord-334123-wb45ww7f	48	4	be	be	VB
cord-334123-wb45ww7f	48	5	designed	design	VBN
cord-334123-wb45ww7f	48	6	to	to	TO
cord-334123-wb45ww7f	48	7	determine	determine	VB
cord-334123-wb45ww7f	48	8	whether	whether	IN
cord-334123-wb45ww7f	48	9	only	only	RB
cord-334123-wb45ww7f	48	10	those	those	DT
cord-334123-wb45ww7f	48	11	which	which	WDT
cord-334123-wb45ww7f	48	12	have	have	VBP
cord-334123-wb45ww7f	48	13	compensa-	compensa-	VBN
cord-334123-wb45ww7f	48	14	(	(	-LRB-
cord-334123-wb45ww7f	48	15	A	a	NN
cord-334123-wb45ww7f	48	16	)	)	-RRB-
cord-334123-wb45ww7f	48	17	Illustration	illustration	NN
cord-334123-wb45ww7f	48	18	of	of	IN
cord-334123-wb45ww7f	48	19	the	the	DT
cord-334123-wb45ww7f	48	20	way	way	NN
cord-334123-wb45ww7f	48	21	in	in	IN
cord-334123-wb45ww7f	48	22	which	which	WDT
cord-334123-wb45ww7f	48	23	the	the	DT
cord-334123-wb45ww7f	48	24	four	four	CD
cord-334123-wb45ww7f	48	25	stems	stem	NNS
cord-334123-wb45ww7f	48	26	of	of	IN
cord-334123-wb45ww7f	48	27	the	the	DT
cord-334123-wb45ww7f	48	28	cloverleaf	cloverleaf	JJ
cord-334123-wb45ww7f	48	29	secondary	secondary	JJ
cord-334123-wb45ww7f	48	30	structure	structure	NN
cord-334123-wb45ww7f	48	31	of	of	IN
cord-334123-wb45ww7f	48	32	a	a	DT
cord-334123-wb45ww7f	48	33	tRNA	trna	NN
cord-334123-wb45ww7f	48	34	are	be	VBP
cord-334123-wb45ww7f	48	35	combined	combine	VBN
cord-334123-wb45ww7f	48	36	into	into	IN
cord-334123-wb45ww7f	48	37	two	two	CD
cord-334123-wb45ww7f	48	38	minihelices	minihelice	NNS
cord-334123-wb45ww7f	48	39	.	.	.
cord-334123-wb45ww7f	49	1	In	in	IN
cord-334123-wb45ww7f	49	2	the	the	DT
cord-334123-wb45ww7f	49	3	case	case	NN
cord-334123-wb45ww7f	49	4	of	of	IN
cord-334123-wb45ww7f	49	5	E.	E.	NNP
cord-334123-wb45ww7f	49	6	coli	coli	NNP
cord-334123-wb45ww7f	49	7	alanine	alanine	NNP
cord-334123-wb45ww7f	49	8	tRNA	tRNA	NNP
cord-334123-wb45ww7f	49	9	,	,	,
cord-334123-wb45ww7f	49	10	the	the	DT
cord-334123-wb45ww7f	49	11	12	12	CD
cord-334123-wb45ww7f	49	12	bp	bp	NNP
cord-334123-wb45ww7f	49	13	acceptor	acceptor	NN
cord-334123-wb45ww7f	49	14	-	-	HYPH
cord-334123-wb45ww7f	49	15	T@	t@	JJ
cord-334123-wb45ww7f	49	16	minihelix	minihelix	NN
cord-334123-wb45ww7f	49	17	can	can	MD
cord-334123-wb45ww7f	49	18	be	be	VB
cord-334123-wb45ww7f	49	19	efficiently	efficiently	RB
cord-334123-wb45ww7f	49	20	aminoacylated	aminoacylate	VBN
cord-334123-wb45ww7f	49	21	,	,	,
cord-334123-wb45ww7f	49	22	provided	provide	VBD
cord-334123-wb45ww7f	49	23	the	the	DT
cord-334123-wb45ww7f	49	24	minihelix	minihelix	NNP
cord-334123-wb45ww7f	49	25	encodes	encode	VBZ
cord-334123-wb45ww7f	49	26	a	a	DT
cord-334123-wb45ww7f	49	27	critical	critical	JJ
cord-334123-wb45ww7f	49	28	G3	G3	NNP
cord-334123-wb45ww7f	49	29	:	:	:
cord-334123-wb45ww7f	49	30	U70	U70	NNP
cord-334123-wb45ww7f	49	31	base	base	NN
cord-334123-wb45ww7f	49	32	pair	pair	NN
cord-334123-wb45ww7f	49	33	(	(	-LRB-
cord-334123-wb45ww7f	49	34	Francklyn	Francklyn	NNP
cord-334123-wb45ww7f	49	35	and	and	CC
cord-334123-wb45ww7f	49	36	Schimmel	Schimmel	NNP
cord-334123-wb45ww7f	49	37	,	,	,
cord-334123-wb45ww7f	49	38	1999	1999	CD
cord-334123-wb45ww7f	49	39	)	)	-RRB-
cord-334123-wb45ww7f	49	40	.	.	.
cord-334123-wb45ww7f	50	1	(	(	-LRB-
cord-334123-wb45ww7f	50	2	B	b	NN
cord-334123-wb45ww7f	50	3	)	)	-RRB-
cord-334123-wb45ww7f	50	4	Generation	generation	NN
cord-334123-wb45ww7f	50	5	of	of	IN
cord-334123-wb45ww7f	50	6	a	a	DT
cord-334123-wb45ww7f	50	7	12	12	CD
cord-334123-wb45ww7f	50	8	bp	bp	NNP
cord-334123-wb45ww7f	50	9	minihelix	minihelix	NNP
cord-334123-wb45ww7f	50	10	by	by	IN
cord-334123-wb45ww7f	50	11	formation	formation	NN
cord-334123-wb45ww7f	50	12	of	of	IN
cord-334123-wb45ww7f	50	13	a	a	DT
cord-334123-wb45ww7f	50	14	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	50	15	.	.	.
cord-334123-wb45ww7f	51	1	This	this	DT
cord-334123-wb45ww7f	51	2	structure	structure	NN
cord-334123-wb45ww7f	51	3	at	at	IN
cord-334123-wb45ww7f	51	4	the	the	DT
cord-334123-wb45ww7f	51	5	3	3	CD
cord-334123-wb45ww7f	51	6	'	'	NN
cord-334123-wb45ww7f	51	7	end	end	NN
cord-334123-wb45ww7f	51	8	of	of	IN
cord-334123-wb45ww7f	51	9	TYMV	TYMV	NNP
cord-334123-wb45ww7f	51	10	RNA	RNA	NNP
cord-334123-wb45ww7f	51	11	can	can	MD
cord-334123-wb45ww7f	51	12	be	be	VB
cord-334123-wb45ww7f	51	13	combined	combine	VBN
cord-334123-wb45ww7f	51	14	with	with	IN
cord-334123-wb45ww7f	51	15	adjacent	adjacent	JJ
cord-334123-wb45ww7f	51	16	sequences	sequence	NNS
cord-334123-wb45ww7f	51	17	to	to	TO
cord-334123-wb45ww7f	51	18	form	form	VB
cord-334123-wb45ww7f	51	19	a	a	DT
cord-334123-wb45ww7f	51	20	complete	complete	JJ
cord-334123-wb45ww7f	51	21	tRNA	trna	NN
cord-334123-wb45ww7f	51	22	-	-	HYPH
cord-334123-wb45ww7f	51	23	like	like	JJ
cord-334123-wb45ww7f	51	24	molecule	molecule	NN
cord-334123-wb45ww7f	51	25	(	(	-LRB-
cord-334123-wb45ww7f	51	26	see	see	VB
cord-334123-wb45ww7f	51	27	Pleij	Pleij	NNP
cord-334123-wb45ww7f	51	28	et	et	NNP
cord-334123-wb45ww7f	51	29	al	al	NNP
cord-334123-wb45ww7f	51	30	.	.	NNP
cord-334123-wb45ww7f	51	31	,	,	,
cord-334123-wb45ww7f	51	32	1995	1995	CD
cord-334123-wb45ww7f	51	33	)	)	-RRB-
cord-334123-wb45ww7f	51	34	.	.	.
cord-334123-wb45ww7f	52	1	tory	tory	NNP
cord-334123-wb45ww7f	52	2	base	base	NNP
cord-334123-wb45ww7f	52	3	changes	change	NNS
cord-334123-wb45ww7f	52	4	that	that	WDT
cord-334123-wb45ww7f	52	5	preserve	preserve	VBP
cord-334123-wb45ww7f	52	6	the	the	DT
cord-334123-wb45ww7f	52	7	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	52	8	can	can	MD
cord-334123-wb45ww7f	52	9	be	be	VB
cord-334123-wb45ww7f	52	10	aminoacylated	aminoacylate	VBN
cord-334123-wb45ww7f	52	11	(	(	-LRB-
cord-334123-wb45ww7f	52	12	cf	cf	NN
cord-334123-wb45ww7f	52	13	.	.	.
cord-334123-wb45ww7f	52	14	Dreher	Dreher	NNP
cord-334123-wb45ww7f	52	15	and	and	CC
cord-334123-wb45ww7f	52	16	Hall	Hall	NNP
cord-334123-wb45ww7f	52	17	,	,	,
cord-334123-wb45ww7f	52	18	1988	1988	CD
cord-334123-wb45ww7f	52	19	)	)	-RRB-
cord-334123-wb45ww7f	52	20	.	.	.
cord-334123-wb45ww7f	53	1	This	this	DT
cord-334123-wb45ww7f	53	2	is	be	VBZ
cord-334123-wb45ww7f	53	3	analogous	analogous	JJ
cord-334123-wb45ww7f	53	4	to	to	IN
cord-334123-wb45ww7f	53	5	the	the	DT
cord-334123-wb45ww7f	53	6	phylogenetic	phylogenetic	JJ
cord-334123-wb45ww7f	53	7	approach	approach	NN
cord-334123-wb45ww7f	53	8	,	,	,
cord-334123-wb45ww7f	53	9	which	which	WDT
cord-334123-wb45ww7f	53	10	has	have	VBZ
cord-334123-wb45ww7f	53	11	been	be	VBN
cord-334123-wb45ww7f	53	12	successfully	successfully	RB
cord-334123-wb45ww7f	53	13	used	use	VBN
cord-334123-wb45ww7f	53	14	to	to	TO
cord-334123-wb45ww7f	53	15	test	test	VB
cord-334123-wb45ww7f	53	16	predictions	prediction	NNS
cord-334123-wb45ww7f	53	17	of	of	IN
cord-334123-wb45ww7f	53	18	secondary	secondary	JJ
cord-334123-wb45ww7f	53	19	structure	structure	NN
cord-334123-wb45ww7f	53	20	in	in	IN
cord-334123-wb45ww7f	53	21	large	large	JJ
cord-334123-wb45ww7f	53	22	RNA	RNA	NNP
cord-334123-wb45ww7f	53	23	molecules	molecule	NNS
cord-334123-wb45ww7f	53	24	(	(	-LRB-
cord-334123-wb45ww7f	53	25	Noller	Noller	NNP
cord-334123-wb45ww7f	53	26	,	,	,
cord-334123-wb45ww7f	53	27	1984	1984	CD
cord-334123-wb45ww7f	53	28	;	;	:
cord-334123-wb45ww7f	53	29	James	James	NNP
cord-334123-wb45ww7f	53	30	et	et	NNP
cord-334123-wb45ww7f	53	31	al	al	NNP
cord-334123-wb45ww7f	53	32	.	.	NNP
cord-334123-wb45ww7f	53	33	,	,	,
cord-334123-wb45ww7f	53	34	1988	1988	CD
cord-334123-wb45ww7f	53	35	)	)	-RRB-
cord-334123-wb45ww7f	53	36	.	.	.
cord-334123-wb45ww7f	54	1	In	in	IN
cord-334123-wb45ww7f	54	2	the	the	DT
cord-334123-wb45ww7f	54	3	case	case	NN
cord-334123-wb45ww7f	54	4	of	of	IN
cord-334123-wb45ww7f	54	5	aminoacylation	aminoacylation	NN
cord-334123-wb45ww7f	54	6	of	of	IN
cord-334123-wb45ww7f	54	7	viral	viral	JJ
cord-334123-wb45ww7f	54	8	RNAs	rna	NNS
cord-334123-wb45ww7f	54	9	,	,	,
cord-334123-wb45ww7f	54	10	however	however	RB
cord-334123-wb45ww7f	54	11	,	,	,
cord-334123-wb45ww7f	54	12	it	-PRON-	PRP
cord-334123-wb45ww7f	54	13	is	be	VBZ
cord-334123-wb45ww7f	54	14	not	not	RB
cord-334123-wb45ww7f	54	15	just	just	RB
cord-334123-wb45ww7f	54	16	a	a	DT
cord-334123-wb45ww7f	54	17	question	question	NN
cord-334123-wb45ww7f	54	18	of	of	IN
cord-334123-wb45ww7f	54	19	formation	formation	NN
cord-334123-wb45ww7f	54	20	of	of	IN
cord-334123-wb45ww7f	54	21	the	the	DT
cord-334123-wb45ww7f	54	22	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	54	23	structure	structure	NN
cord-334123-wb45ww7f	54	24	,	,	,
cord-334123-wb45ww7f	54	25	but	but	CC
cord-334123-wb45ww7f	54	26	of	of	IN
cord-334123-wb45ww7f	54	27	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	54	28	-	-	HYPH
cord-334123-wb45ww7f	54	29	dependent	dependent	JJ
cord-334123-wb45ww7f	54	30	presentation	presentation	NN
cord-334123-wb45ww7f	54	31	of	of	IN
cord-334123-wb45ww7f	54	32	nucleotide	nucleotide	JJ
cord-334123-wb45ww7f	54	33	determinants	determinant	NNS
cord-334123-wb45ww7f	54	34	for	for	IN
cord-334123-wb45ww7f	54	35	protein	protein	NN
cord-334123-wb45ww7f	54	36	recognition	recognition	NN
cord-334123-wb45ww7f	54	37	.	.	.
cord-334123-wb45ww7f	55	1	Consequently	consequently	RB
cord-334123-wb45ww7f	55	2	,	,	,
cord-334123-wb45ww7f	55	3	both	both	DT
cord-334123-wb45ww7f	55	4	mutations	mutation	NNS
cord-334123-wb45ww7f	55	5	that	that	WDT
cord-334123-wb45ww7f	55	6	disrupt	disrupt	VBP
cord-334123-wb45ww7f	55	7	and	and	CC
cord-334123-wb45ww7f	55	8	others	other	NNS
cord-334123-wb45ww7f	55	9	that	that	WDT
cord-334123-wb45ww7f	55	10	preserve	preserve	VBP
cord-334123-wb45ww7f	55	11	the	the	DT
cord-334123-wb45ww7f	55	12	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	55	13	may	may	MD
cord-334123-wb45ww7f	55	14	inactivate	inactivate	VB
cord-334123-wb45ww7f	55	15	aminoacylation	aminoacylation	NN
cord-334123-wb45ww7f	55	16	and	and	CC
cord-334123-wb45ww7f	55	17	,	,	,
cord-334123-wb45ww7f	55	18	therefore	therefore	RB
cord-334123-wb45ww7f	55	19	,	,	,
cord-334123-wb45ww7f	55	20	must	must	MD
cord-334123-wb45ww7f	55	21	be	be	VB
cord-334123-wb45ww7f	55	22	classified	classify	VBN
cord-334123-wb45ww7f	55	23	and	and	CC
cord-334123-wb45ww7f	55	24	studied	study	VBN
cord-334123-wb45ww7f	55	25	separately	separately	RB
cord-334123-wb45ww7f	55	26	.	.	.
cord-334123-wb45ww7f	56	1	Obviously	obviously	RB
cord-334123-wb45ww7f	56	2	,	,	,
cord-334123-wb45ww7f	56	3	this	this	DT
cord-334123-wb45ww7f	56	4	analysis	analysis	NN
cord-334123-wb45ww7f	56	5	would	would	MD
cord-334123-wb45ww7f	56	6	be	be	VB
cord-334123-wb45ww7f	56	7	more	more	RBR
cord-334123-wb45ww7f	56	8	effective	effective	JJ
cord-334123-wb45ww7f	56	9	if	if	IN
cord-334123-wb45ww7f	56	10	the	the	DT
cord-334123-wb45ww7f	56	11	sites	site	NNS
cord-334123-wb45ww7f	56	12	for	for	IN
cord-334123-wb45ww7f	56	13	synthetase	synthetase	NN
cord-334123-wb45ww7f	56	14	recognition	recognition	NN
cord-334123-wb45ww7f	56	15	in	in	IN
cord-334123-wb45ww7f	56	16	the	the	DT
cord-334123-wb45ww7f	56	17	associated	associate	VBN
cord-334123-wb45ww7f	56	18	tRNA	tRNA	NNP
cord-334123-wb45ww7f	56	19	were	be	VBD
cord-334123-wb45ww7f	56	20	already	already	RB
cord-334123-wb45ww7f	56	21	known	know	VBN
cord-334123-wb45ww7f	56	22	,	,	,
cord-334123-wb45ww7f	56	23	but	but	CC
cord-334123-wb45ww7f	56	24	to	to	IN
cord-334123-wb45ww7f	56	25	date	date	NN
cord-334123-wb45ww7f	56	26	,	,	,
cord-334123-wb45ww7f	56	27	examples	example	NNS
cord-334123-wb45ww7f	56	28	for	for	IN
cord-334123-wb45ww7f	56	29	which	which	WDT
cord-334123-wb45ww7f	56	30	the	the	DT
cord-334123-wb45ww7f	56	31	sites	site	NNS
cord-334123-wb45ww7f	56	32	for	for	IN
cord-334123-wb45ww7f	56	33	tRNA	trna	NN
cord-334123-wb45ww7f	56	34	identity	identity	NN
cord-334123-wb45ww7f	56	35	are	be	VBP
cord-334123-wb45ww7f	56	36	well	well	RB
cord-334123-wb45ww7f	56	37	defined	define	VBN
cord-334123-wb45ww7f	56	38	have	have	VBP
cord-334123-wb45ww7f	56	39	no	no	DT
cord-334123-wb45ww7f	56	40	viral	viral	JJ
cord-334123-wb45ww7f	56	41	RNA	RNA	NNP
cord-334123-wb45ww7f	56	42	counterpart	counterpart	NN
cord-334123-wb45ww7f	56	43	.	.	.
cord-334123-wb45ww7f	57	1	The	the	DT
cord-334123-wb45ww7f	57	2	first	first	JJ
cord-334123-wb45ww7f	57	3	evidence	evidence	NN
cord-334123-wb45ww7f	57	4	for	for	IN
cord-334123-wb45ww7f	57	5	a	a	DT
cord-334123-wb45ww7f	57	6	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	57	7	motif	motif	NN
cord-334123-wb45ww7f	57	8	in	in	IN
cord-334123-wb45ww7f	57	9	protein	protein	NN
cord-334123-wb45ww7f	57	10	binding	bind	VBG
cord-334123-wb45ww7f	57	11	to	to	IN
cord-334123-wb45ww7f	57	12	an	an	DT
cord-334123-wb45ww7f	57	13	mRNA	mrna	NN
cord-334123-wb45ww7f	57	14	came	come	VBD
cord-334123-wb45ww7f	57	15	from	from	IN
cord-334123-wb45ww7f	57	16	experiments	experiment	NNS
cord-334123-wb45ww7f	57	17	by	by	IN
cord-334123-wb45ww7f	57	18	McPheeters	McPheeters	NNP
cord-334123-wb45ww7f	57	19	et	et	NNP
cord-334123-wb45ww7f	57	20	al	al	NNP
cord-334123-wb45ww7f	57	21	.	.	.
cord-334123-wb45ww7f	58	1	(	(	-LRB-
cord-334123-wb45ww7f	58	2	1988	1988	CD
cord-334123-wb45ww7f	58	3	)	)	-RRB-
cord-334123-wb45ww7f	58	4	,	,	,
cord-334123-wb45ww7f	58	5	who	who	WP
cord-334123-wb45ww7f	58	6	dissected	dissect	VBD
cord-334123-wb45ww7f	58	7	the	the	DT
cord-334123-wb45ww7f	58	8	translational	translational	JJ
cord-334123-wb45ww7f	58	9	regulatory	regulatory	JJ
cord-334123-wb45ww7f	58	10	site	site	NN
cord-334123-wb45ww7f	58	11	on	on	IN
cord-334123-wb45ww7f	58	12	bacteriophage	bacteriophage	NN
cord-334123-wb45ww7f	58	13	T4	T4	NNP
cord-334123-wb45ww7f	58	14	gene	gene	NN
cord-334123-wb45ww7f	58	15	32	32	CD
cord-334123-wb45ww7f	58	16	mRNA	mrna	NN
cord-334123-wb45ww7f	58	17	.	.	.
cord-334123-wb45ww7f	59	1	Gene	gene	NN
cord-334123-wb45ww7f	59	2	32	32	CD
cord-334123-wb45ww7f	59	3	protein	protein	NN
cord-334123-wb45ww7f	59	4	binds	bind	VBZ
cord-334123-wb45ww7f	59	5	to	to	IN
cord-334123-wb45ww7f	59	6	single	single	RB
cord-334123-wb45ww7f	59	7	-	-	HYPH
cord-334123-wb45ww7f	59	8	stranded	strand	VBN
cord-334123-wb45ww7f	59	9	DNA	dna	NN
cord-334123-wb45ww7f	59	10	and	and	CC
cord-334123-wb45ww7f	59	11	has	have	VBZ
cord-334123-wb45ww7f	59	12	a	a	DT
cord-334123-wb45ww7f	59	13	functional	functional	JJ
cord-334123-wb45ww7f	59	14	role	role	NN
cord-334123-wb45ww7f	59	15	in	in	IN
cord-334123-wb45ww7f	59	16	T4	T4	NNP
cord-334123-wb45ww7f	59	17	DNA	DNA	NNP
cord-334123-wb45ww7f	59	18	transactions	transaction	NNS
cord-334123-wb45ww7f	59	19	;	;	:
cord-334123-wb45ww7f	59	20	excess	excess	JJ
cord-334123-wb45ww7f	59	21	amounts	amount	NNS
cord-334123-wb45ww7f	59	22	of	of	IN
cord-334123-wb45ww7f	59	23	the	the	DT
cord-334123-wb45ww7f	59	24	protein	protein	NN
cord-334123-wb45ww7f	59	25	are	be	VBP
cord-334123-wb45ww7f	59	26	free	free	JJ
cord-334123-wb45ww7f	59	27	to	to	TO
cord-334123-wb45ww7f	59	28	bind	bind	VB
cord-334123-wb45ww7f	59	29	to	to	IN
cord-334123-wb45ww7f	59	30	the	the	DT
cord-334123-wb45ww7f	59	31	operator	operator	NN
cord-334123-wb45ww7f	59	32	region	region	NN
cord-334123-wb45ww7f	59	33	of	of	IN
cord-334123-wb45ww7f	59	34	its	-PRON-	PRP$
cord-334123-wb45ww7f	59	35	mRNA	mrna	NN
cord-334123-wb45ww7f	59	36	and	and	CC
cord-334123-wb45ww7f	59	37	thereby	thereby	RB
cord-334123-wb45ww7f	59	38	block	block	VB
cord-334123-wb45ww7f	59	39	initiation	initiation	NN
cord-334123-wb45ww7f	59	40	of	of	IN
cord-334123-wb45ww7f	59	41	translation	translation	NN
cord-334123-wb45ww7f	59	42	(	(	-LRB-
cord-334123-wb45ww7f	59	43	Gold	gold	NN
cord-334123-wb45ww7f	59	44	,	,	,
cord-334123-wb45ww7f	59	45	1988	1988	CD
cord-334123-wb45ww7f	59	46	)	)	-RRB-
cord-334123-wb45ww7f	59	47	.	.	.
cord-334123-wb45ww7f	60	1	By	by	IN
cord-334123-wb45ww7f	60	2	a	a	DT
cord-334123-wb45ww7f	60	3	combination	combination	NN
cord-334123-wb45ww7f	60	4	of	of	IN
cord-334123-wb45ww7f	60	5	methods	method	NNS
cord-334123-wb45ww7f	60	6	which	which	WDT
cord-334123-wb45ww7f	60	7	were	be	VBD
cord-334123-wb45ww7f	60	8	applied	apply	VBN
cord-334123-wb45ww7f	60	9	to	to	IN
cord-334123-wb45ww7f	60	10	free	free	JJ
cord-334123-wb45ww7f	60	11	and	and	CC
cord-334123-wb45ww7f	60	12	complexed	complexed	JJ
cord-334123-wb45ww7f	60	13	RNA	RNA	NNP
cord-334123-wb45ww7f	60	14	,	,	,
cord-334123-wb45ww7f	60	15	nucleation	nucleation	NN
cord-334123-wb45ww7f	60	16	of	of	IN
cord-334123-wb45ww7f	60	17	binding	binding	NN
cord-334123-wb45ww7f	60	18	was	be	VBD
cord-334123-wb45ww7f	60	19	suggested	suggest	VBN
cord-334123-wb45ww7f	60	20	to	to	TO
cord-334123-wb45ww7f	60	21	be	be	VB
cord-334123-wb45ww7f	60	22	promoted	promote	VBN
cord-334123-wb45ww7f	60	23	by	by	IN
cord-334123-wb45ww7f	60	24	a	a	DT
cord-334123-wb45ww7f	60	25	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	60	26	that	that	WDT
cord-334123-wb45ww7f	60	27	is	be	VBZ
cord-334123-wb45ww7f	60	28	approximately	approximately	RB
cord-334123-wb45ww7f	60	29	40	40	CD
cord-334123-wb45ww7f	60	30	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	60	31	upstream	upstream	RB
cord-334123-wb45ww7f	60	32	of	of	IN
cord-334123-wb45ww7f	60	33	the	the	DT
cord-334123-wb45ww7f	60	34	initiation	initiation	NN
cord-334123-wb45ww7f	60	35	codon	codon	NN
cord-334123-wb45ww7f	60	36	.	.	.
cord-334123-wb45ww7f	61	1	A	a	DT
cord-334123-wb45ww7f	61	2	comparison	comparison	NN
cord-334123-wb45ww7f	61	3	with	with	IN
cord-334123-wb45ww7f	61	4	the	the	DT
cord-334123-wb45ww7f	61	5	mRNA	mRNA	NNP
cord-334123-wb45ww7f	61	6	sequences	sequence	NNS
cord-334123-wb45ww7f	61	7	of	of	IN
cord-334123-wb45ww7f	61	8	the	the	DT
cord-334123-wb45ww7f	61	9	related	related	JJ
cord-334123-wb45ww7f	61	10	T2	T2	NNP
cord-334123-wb45ww7f	61	11	and	and	CC
cord-334123-wb45ww7f	61	12	T8	T8	NNP
cord-334123-wb45ww7f	61	13	phages	phage	NNS
cord-334123-wb45ww7f	61	14	provided	provide	VBD
cord-334123-wb45ww7f	61	15	phylogenetic	phylogenetic	JJ
cord-334123-wb45ww7f	61	16	evidence	evidence	NN
cord-334123-wb45ww7f	61	17	for	for	IN
cord-334123-wb45ww7f	61	18	conservation	conservation	NN
cord-334123-wb45ww7f	61	19	of	of	IN
cord-334123-wb45ww7f	61	20	the	the	DT
cord-334123-wb45ww7f	61	21	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	61	22	structure	structure	NN
cord-334123-wb45ww7f	62	1	(	(	-LRB-
cord-334123-wb45ww7f	62	2	McPheeters	McPheeters	NNP
cord-334123-wb45ww7f	62	3	et	et	NNP
cord-334123-wb45ww7f	62	4	al	al	NNP
cord-334123-wb45ww7f	62	5	.	.	NNP
cord-334123-wb45ww7f	62	6	,	,	,
cord-334123-wb45ww7f	62	7	1988	1988	CD
cord-334123-wb45ww7f	62	8	)	)	-RRB-
cord-334123-wb45ww7f	62	9	.	.	.
cord-334123-wb45ww7f	63	1	To	to	TO
cord-334123-wb45ww7f	63	2	understand	understand	VB
cord-334123-wb45ww7f	63	3	the	the	DT
cord-334123-wb45ww7f	63	4	exact	exact	JJ
cord-334123-wb45ww7f	63	5	structure	structure	NN
cord-334123-wb45ww7f	63	6	required	require	VBN
cord-334123-wb45ww7f	63	7	for	for	IN
cord-334123-wb45ww7f	63	8	presentation	presentation	NN
cord-334123-wb45ww7f	63	9	of	of	IN
cord-334123-wb45ww7f	63	10	the	the	DT
cord-334123-wb45ww7f	63	11	gene	gene	NN
cord-334123-wb45ww7f	63	12	32	32	CD
cord-334123-wb45ww7f	63	13	protein	protein	NN
cord-334123-wb45ww7f	63	14	binding	binding	NN
cord-334123-wb45ww7f	63	15	site	site	NN
cord-334123-wb45ww7f	63	16	,	,	,
cord-334123-wb45ww7f	63	17	direct	direct	JJ
cord-334123-wb45ww7f	63	18	and	and	CC
cord-334123-wb45ww7f	63	19	quantitative	quantitative	JJ
cord-334123-wb45ww7f	63	20	measurements	measurement	NNS
cord-334123-wb45ww7f	63	21	of	of	IN
cord-334123-wb45ww7f	63	22	protein	protein	NN
cord-334123-wb45ww7f	63	23	binding	bind	VBG
cord-334123-wb45ww7f	63	24	to	to	IN
cord-334123-wb45ww7f	63	25	an	an	DT
cord-334123-wb45ww7f	63	26	RNA	RNA	NNP
cord-334123-wb45ww7f	63	27	with	with	IN
cord-334123-wb45ww7f	63	28	the	the	DT
cord-334123-wb45ww7f	63	29	presumed	presume	VBN
cord-334123-wb45ww7f	63	30	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	63	31	,	,	,
cord-334123-wb45ww7f	63	32	and	and	CC
cord-334123-wb45ww7f	63	33	to	to	IN
cord-334123-wb45ww7f	63	34	mutants	mutant	NNS
cord-334123-wb45ww7f	63	35	that	that	WDT
cord-334123-wb45ww7f	63	36	alter	alter	VBP
cord-334123-wb45ww7f	63	37	its	-PRON-	PRP$
cord-334123-wb45ww7f	63	38	structure	structure	NN
cord-334123-wb45ww7f	63	39	,	,	,
cord-334123-wb45ww7f	63	40	will	will	MD
cord-334123-wb45ww7f	63	41	have	have	VB
cord-334123-wb45ww7f	63	42	to	to	TO
cord-334123-wb45ww7f	63	43	be	be	VB
cord-334123-wb45ww7f	63	44	carried	carry	VBN
cord-334123-wb45ww7f	63	45	out	out	RP
cord-334123-wb45ww7f	63	46	.	.	.
cord-334123-wb45ww7f	64	1	Two	two	CD
cord-334123-wb45ww7f	64	2	,	,	,
cord-334123-wb45ww7f	64	3	recent	recent	JJ
cord-334123-wb45ww7f	64	4	studies	study	NNS
cord-334123-wb45ww7f	64	5	have	have	VBP
cord-334123-wb45ww7f	64	6	used	use	VBN
cord-334123-wb45ww7f	64	7	mutational	mutational	JJ
cord-334123-wb45ww7f	64	8	analysis	analysis	NN
cord-334123-wb45ww7f	64	9	to	to	TO
cord-334123-wb45ww7f	64	10	demonstrate	demonstrate	VB
cord-334123-wb45ww7f	64	11	the	the	DT
cord-334123-wb45ww7f	64	12	role	role	NN
cord-334123-wb45ww7f	64	13	of	of	IN
cord-334123-wb45ww7f	64	14	pseudoknots	pseudoknot	NNS
cord-334123-wb45ww7f	64	15	in	in	IN
cord-334123-wb45ww7f	64	16	entirely	entirely	RB
cord-334123-wb45ww7f	64	17	different	different	JJ
cord-334123-wb45ww7f	64	18	systems	system	NNS
cord-334123-wb45ww7f	64	19	.	.	.
cord-334123-wb45ww7f	65	1	One	one	CD
cord-334123-wb45ww7f	65	2	is	be	VBZ
cord-334123-wb45ww7f	65	3	an	an	DT
cord-334123-wb45ww7f	65	4	investigation	investigation	NN
cord-334123-wb45ww7f	65	5	of	of	IN
cord-334123-wb45ww7f	65	6	protein	protein	NN
cord-334123-wb45ww7f	65	7	recognition	recognition	NN
cord-334123-wb45ww7f	65	8	of	of	IN
cord-334123-wb45ww7f	65	9	a	a	DT
cord-334123-wb45ww7f	65	10	proposed	propose	VBN
cord-334123-wb45ww7f	65	11	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	65	12	motif	motif	NN
cord-334123-wb45ww7f	65	13	in	in	IN
cord-334123-wb45ww7f	65	14	the	the	DT
cord-334123-wb45ww7f	65	15	5	5	CD
cord-334123-wb45ww7f	65	16	'	'	''
cord-334123-wb45ww7f	65	17	region	region	NN
cord-334123-wb45ww7f	65	18	of	of	IN
cord-334123-wb45ww7f	65	19	the	the	DT
cord-334123-wb45ww7f	65	20	E.	E.	NNP
cord-334123-wb45ww7f	65	21	coli	coli	VBZ
cord-334123-wb45ww7f	65	22	a	a	DT
cord-334123-wb45ww7f	65	23	operon	operon	NN
cord-334123-wb45ww7f	65	24	mRNA	mrna	NN
cord-334123-wb45ww7f	66	1	(	(	-LRB-
cord-334123-wb45ww7f	66	2	Tang	Tang	NNP
cord-334123-wb45ww7f	66	3	and	and	CC
cord-334123-wb45ww7f	66	4	Draper	Draper	NNP
cord-334123-wb45ww7f	66	5	,	,	,
cord-334123-wb45ww7f	66	6	1989	1989	CD
cord-334123-wb45ww7f	66	7	)	)	-RRB-
cord-334123-wb45ww7f	66	8	.	.	.
cord-334123-wb45ww7f	67	1	This	this	DT
cord-334123-wb45ww7f	67	2	polycistronic	polycistronic	NNP
cord-334123-wb45ww7f	67	3	mRNA	mrna	NN
cord-334123-wb45ww7f	67	4	encodes	encode	VBZ
cord-334123-wb45ww7f	67	5	four	four	CD
cord-334123-wb45ww7f	67	6	ribosomal	ribosomal	JJ
cord-334123-wb45ww7f	67	7	proteins	protein	NNS
cord-334123-wb45ww7f	67	8	and	and	CC
cord-334123-wb45ww7f	67	9	the	the	DT
cord-334123-wb45ww7f	67	10	a	a	DT
cord-334123-wb45ww7f	67	11	subunit	subunit	NN
cord-334123-wb45ww7f	67	12	of	of	IN
cord-334123-wb45ww7f	67	13	RNA	RNA	NNP
cord-334123-wb45ww7f	67	14	polymerase	polymerase	NN
cord-334123-wb45ww7f	67	15	.	.	.
cord-334123-wb45ww7f	68	1	Ribosomal	ribosomal	JJ
cord-334123-wb45ww7f	68	2	protein	protein	NN
cord-334123-wb45ww7f	68	3	S4	s4	NN
cord-334123-wb45ww7f	68	4	is	be	VBZ
cord-334123-wb45ww7f	68	5	one	one	CD
cord-334123-wb45ww7f	68	6	of	of	IN
cord-334123-wb45ww7f	68	7	the	the	DT
cord-334123-wb45ww7f	68	8	encoded	encode	VBN
cord-334123-wb45ww7f	68	9	proteins	protein	NNS
cord-334123-wb45ww7f	68	10	.	.	.
cord-334123-wb45ww7f	69	1	The	the	DT
cord-334123-wb45ww7f	69	2	translation	translation	NN
cord-334123-wb45ww7f	69	3	of	of	IN
cord-334123-wb45ww7f	69	4	this	this	DT
cord-334123-wb45ww7f	69	5	mRNA	mrna	NN
cord-334123-wb45ww7f	69	6	is	be	VBZ
cord-334123-wb45ww7f	69	7	regulated	regulate	VBN
cord-334123-wb45ww7f	69	8	by	by	IN
cord-334123-wb45ww7f	69	9	S4	S4	NNP
cord-334123-wb45ww7f	69	10	.	.	.
cord-334123-wb45ww7f	70	1	This	this	DT
cord-334123-wb45ww7f	70	2	and	and	CC
cord-334123-wb45ww7f	70	3	other	other	JJ
cord-334123-wb45ww7f	70	4	ribosomal	ribosomal	JJ
cord-334123-wb45ww7f	70	5	proteins	protein	NNS
cord-334123-wb45ww7f	70	6	that	that	WDT
cord-334123-wb45ww7f	70	7	are	be	VBP
cord-334123-wb45ww7f	70	8	known	know	VBN
cord-334123-wb45ww7f	70	9	to	to	TO
cord-334123-wb45ww7f	70	10	be	be	VB
cord-334123-wb45ww7f	70	11	translational	translational	JJ
cord-334123-wb45ww7f	70	12	repressors	repressor	NNS
cord-334123-wb45ww7f	70	13	bind	bind	VBP
cord-334123-wb45ww7f	70	14	to	to	IN
cord-334123-wb45ww7f	70	15	a	a	DT
cord-334123-wb45ww7f	70	16	specific	specific	JJ
cord-334123-wb45ww7f	70	17	mRNA	mrna	NN
cord-334123-wb45ww7f	70	18	structure	structure	NN
cord-334123-wb45ww7f	70	19	and	and	CC
cord-334123-wb45ww7f	70	20	also	also	RB
cord-334123-wb45ww7f	70	21	have	have	VB
cord-334123-wb45ww7f	70	22	a	a	DT
cord-334123-wb45ww7f	70	23	binding	binding	JJ
cord-334123-wb45ww7f	70	24	site	site	NN
cord-334123-wb45ww7f	70	25	on	on	IN
cord-334123-wb45ww7f	70	26	16s	16	NNS
cord-334123-wb45ww7f	70	27	or	or	CC
cord-334123-wb45ww7f	70	28	23s	23s	NNPS
cord-334123-wb45ww7f	70	29	ribosomal	ribosomal	NNP
cord-334123-wb45ww7f	70	30	RNA	RNA	NNP
cord-334123-wb45ww7f	70	31	(	(	-LRB-
cord-334123-wb45ww7f	70	32	Lindahl	Lindahl	NNP
cord-334123-wb45ww7f	70	33	and	and	CC
cord-334123-wb45ww7f	70	34	Zengel	Zengel	NNP
cord-334123-wb45ww7f	70	35	,	,	,
cord-334123-wb45ww7f	70	36	1986	1986	CD
cord-334123-wb45ww7f	70	37	;	;	:
cord-334123-wb45ww7f	70	38	Thomas	Thomas	NNP
cord-334123-wb45ww7f	70	39	et	et	NNP
cord-334123-wb45ww7f	70	40	al	al	NNP
cord-334123-wb45ww7f	70	41	.	.	NNP
cord-334123-wb45ww7f	70	42	,	,	,
cord-334123-wb45ww7f	70	43	1987	1987	CD
cord-334123-wb45ww7f	70	44	)	)	-RRB-
cord-334123-wb45ww7f	70	45	.	.	.
cord-334123-wb45ww7f	71	1	Previous	previous	JJ
cord-334123-wb45ww7f	71	2	structural	structural	JJ
cord-334123-wb45ww7f	71	3	mapping	mapping	NN
cord-334123-wb45ww7f	71	4	experiments	experiment	NNS
cord-334123-wb45ww7f	71	5	by	by	IN
cord-334123-wb45ww7f	71	6	Draper	Draper	NNP
cord-334123-wb45ww7f	71	7	and	and	CC
cord-334123-wb45ww7f	71	8	co	co	NNS
cord-334123-wb45ww7f	71	9	-	-	NNS
cord-334123-wb45ww7f	71	10	workers	worker	NNS
cord-334123-wb45ww7f	71	11	suggested	suggest	VBD
cord-334123-wb45ww7f	71	12	a	a	DT
cord-334123-wb45ww7f	71	13	model	model	NN
cord-334123-wb45ww7f	71	14	for	for	IN
cord-334123-wb45ww7f	71	15	the	the	DT
cord-334123-wb45ww7f	71	16	5	5	CD
cord-334123-wb45ww7f	71	17	'	'	POS
cord-334123-wb45ww7f	71	18	region	region	NN
cord-334123-wb45ww7f	71	19	of	of	IN
cord-334123-wb45ww7f	71	20	the	the	DT
cord-334123-wb45ww7f	71	21	mRNA	mrna	NN
cord-334123-wb45ww7f	71	22	which	which	WDT
cord-334123-wb45ww7f	71	23	constitutes	constitute	VBZ
cord-334123-wb45ww7f	71	24	the	the	DT
cord-334123-wb45ww7f	71	25	S4	S4	NNP
cord-334123-wb45ww7f	71	26	binding	binding	NN
cord-334123-wb45ww7f	71	27	site	site	NN
cord-334123-wb45ww7f	71	28	;	;	:
cord-334123-wb45ww7f	71	29	it	-PRON-	PRP
cord-334123-wb45ww7f	71	30	envisions	envision	VBZ
cord-334123-wb45ww7f	71	31	a	a	DT
cord-334123-wb45ww7f	71	32	hairpin	hairpin	JJ
cord-334123-wb45ww7f	71	33	helix	helix	NN
cord-334123-wb45ww7f	71	34	and	and	CC
cord-334123-wb45ww7f	71	35	loop	loop	NN
cord-334123-wb45ww7f	71	36	that	that	WDT
cord-334123-wb45ww7f	71	37	encompasses	encompass	VBZ
cord-334123-wb45ww7f	71	38	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	71	39	19	19	CD
cord-334123-wb45ww7f	71	40	to	to	IN
cord-334123-wb45ww7f	71	41	72	72	CD
cord-334123-wb45ww7f	71	42	.	.	.
cord-334123-wb45ww7f	72	1	The	the	DT
cord-334123-wb45ww7f	72	2	loop	loop	NN
cord-334123-wb45ww7f	72	3	sequence	sequence	NN
cord-334123-wb45ww7f	72	4	GGGC	GGGC	NNP
cord-334123-wb45ww7f	72	5	at	at	IN
cord-334123-wb45ww7f	72	6	position	position	NN
cord-334123-wb45ww7f	72	7	49	49	CD
cord-334123-wb45ww7f	72	8	-	-	SYM
cord-334123-wb45ww7f	72	9	52	52	CD
cord-334123-wb45ww7f	72	10	is	be	VBZ
cord-334123-wb45ww7f	72	11	proposed	propose	VBN
cord-334123-wb45ww7f	72	12	to	to	TO
cord-334123-wb45ww7f	72	13	pair	pair	VB
cord-334123-wb45ww7f	72	14	with	with	IN
cord-334123-wb45ww7f	72	15	the	the	DT
cord-334123-wb45ww7f	72	16	downstream	downstream	JJ
cord-334123-wb45ww7f	72	17	sequence	sequence	NN
cord-334123-wb45ww7f	72	18	GCCC	GCCC	NNP
cord-334123-wb45ww7f	72	19	at	at	IN
cord-334123-wb45ww7f	72	20	position	position	NN
cord-334123-wb45ww7f	72	21	98	98	CD
cord-334123-wb45ww7f	72	22	-	-	SYM
cord-334123-wb45ww7f	72	23	101	101	CD
cord-334123-wb45ww7f	72	24	so	so	IN
cord-334123-wb45ww7f	72	25	as	as	IN
cord-334123-wb45ww7f	72	26	to	to	TO
cord-334123-wb45ww7f	72	27	create	create	VB
cord-334123-wb45ww7f	72	28	a	a	DT
cord-334123-wb45ww7f	72	29	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	72	30	.	.	.
cord-334123-wb45ww7f	73	1	The	the	DT
cord-334123-wb45ww7f	73	2	structural	structural	JJ
cord-334123-wb45ww7f	73	3	model	model	NN
cord-334123-wb45ww7f	73	4	and	and	CC
cord-334123-wb45ww7f	73	5	its	-PRON-	PRP$
cord-334123-wb45ww7f	73	6	relevance	relevance	NN
cord-334123-wb45ww7f	73	7	to	to	IN
cord-334123-wb45ww7f	73	8	S4	s4	NN
cord-334123-wb45ww7f	73	9	binding	binding	NN
cord-334123-wb45ww7f	73	10	was	be	VBD
cord-334123-wb45ww7f	73	11	tested	test	VBN
cord-334123-wb45ww7f	73	12	by	by	IN
cord-334123-wb45ww7f	73	13	construction	construction	NN
cord-334123-wb45ww7f	73	14	of	of	IN
cord-334123-wb45ww7f	73	15	mutants	mutant	NNS
cord-334123-wb45ww7f	73	16	that	that	WDT
cord-334123-wb45ww7f	73	17	alternately	alternately	RB
cord-334123-wb45ww7f	73	18	disrupt	disrupt	VBP
cord-334123-wb45ww7f	73	19	and	and	CC
cord-334123-wb45ww7f	73	20	restore	restore	VB
cord-334123-wb45ww7f	73	21	(	(	-LRB-
cord-334123-wb45ww7f	73	22	by	by	IN
cord-334123-wb45ww7f	73	23	compensatory	compensatory	JJ
cord-334123-wb45ww7f	73	24	changes	change	NNS
cord-334123-wb45ww7f	73	25	)	)	-RRB-
cord-334123-wb45ww7f	73	26	the	the	DT
cord-334123-wb45ww7f	73	27	presumed	presume	VBN
cord-334123-wb45ww7f	73	28	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	73	29	.	.	.
cord-334123-wb45ww7f	74	1	The	the	DT
cord-334123-wb45ww7f	74	2	mutant	mutant	JJ
cord-334123-wb45ww7f	74	3	RNAs	rna	NNS
cord-334123-wb45ww7f	74	4	were	be	VBD
cord-334123-wb45ww7f	74	5	synthesized	synthesize	VBN
cord-334123-wb45ww7f	74	6	by	by	IN
cord-334123-wb45ww7f	74	7	enzymatic	enzymatic	JJ
cord-334123-wb45ww7f	74	8	methods	method	NNS
cord-334123-wb45ww7f	74	9	and	and	CC
cord-334123-wb45ww7f	74	10	assayed	assay	VBN
cord-334123-wb45ww7f	74	11	directly	directly	RB
cord-334123-wb45ww7f	74	12	for	for	IN
cord-334123-wb45ww7f	74	13	S4	s4	NN
cord-334123-wb45ww7f	74	14	binding	binding	NN
cord-334123-wb45ww7f	74	15	in	in	IN
cord-334123-wb45ww7f	74	16	vitro	vitro	FW
cord-334123-wb45ww7f	74	17	(	(	-LRB-
cord-334123-wb45ww7f	75	1	Tang	Tang	NNP
cord-334123-wb45ww7f	75	2	and	and	CC
cord-334123-wb45ww7f	75	3	Draper	Draper	NNP
cord-334123-wb45ww7f	75	4	,	,	,
cord-334123-wb45ww7f	75	5	1989	1989	CD
cord-334123-wb45ww7f	75	6	)	)	-RRB-
cord-334123-wb45ww7f	75	7	.	.	.
cord-334123-wb45ww7f	76	1	Nucleotide	nucleotide	JJ
cord-334123-wb45ww7f	76	2	substitutions	substitution	NNS
cord-334123-wb45ww7f	76	3	that	that	WDT
cord-334123-wb45ww7f	76	4	disrupt	disrupt	VBP
cord-334123-wb45ww7f	76	5	the	the	DT
cord-334123-wb45ww7f	76	6	proposed	propose	VBN
cord-334123-wb45ww7f	76	7	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	76	8	also	also	RB
cord-334123-wb45ww7f	76	9	weaken	weaken	VB
cord-334123-wb45ww7f	76	10	S4	S4	NNP
cord-334123-wb45ww7f	76	11	binding	binding	NN
cord-334123-wb45ww7f	76	12	.	.	.
cord-334123-wb45ww7f	77	1	Several	several	JJ
cord-334123-wb45ww7f	77	2	compensatory	compensatory	JJ
cord-334123-wb45ww7f	77	3	mutations	mutation	NNS
cord-334123-wb45ww7f	77	4	which	which	WDT
cord-334123-wb45ww7f	77	5	restore	restore	VBP
cord-334123-wb45ww7f	77	6	base	base	NN
cord-334123-wb45ww7f	77	7	pairing	pairing	NN
cord-334123-wb45ww7f	77	8	also	also	RB
cord-334123-wb45ww7f	77	9	restore	restore	VB
cord-334123-wb45ww7f	77	10	binding	bind	VBG
cord-334123-wb45ww7f	77	11	affinity	affinity	NN
cord-334123-wb45ww7f	77	12	.	.	.
cord-334123-wb45ww7f	78	1	For	for	IN
cord-334123-wb45ww7f	78	2	example	example	NN
cord-334123-wb45ww7f	78	3	,	,	,
cord-334123-wb45ww7f	78	4	the	the	DT
cord-334123-wb45ww7f	78	5	G49G5,-,+CC	g49g5,-,+cc	CD
cord-334123-wb45ww7f	78	6	and	and	CC
cord-334123-wb45ww7f	78	7	ClooClol	ClooClol	NNP
cord-334123-wb45ww7f	78	8	~	~	NFP
cord-334123-wb45ww7f	78	9	G	g	NN
cord-334123-wb45ww7f	78	10	mutants	mutant	NNS
cord-334123-wb45ww7f	78	11	are	be	VBP
cord-334123-wb45ww7f	78	12	each	each	DT
cord-334123-wb45ww7f	78	13	recognized	recognize	VBN
cord-334123-wb45ww7f	78	14	by	by	IN
cord-334123-wb45ww7f	78	15	S4	S4	NNP
cord-334123-wb45ww7f	78	16	with	with	IN
cord-334123-wb45ww7f	78	17	an	an	DT
cord-334123-wb45ww7f	78	18	6-to	6-to	CD
cord-334123-wb45ww7f	78	19	lo	lo	NN
cord-334123-wb45ww7f	78	20	-	-	:
cord-334123-wb45ww7f	78	21	fold	fold	VB
cord-334123-wb45ww7f	78	22	lower	low	JJR
cord-334123-wb45ww7f	78	23	affinity	affinity	NN
cord-334123-wb45ww7f	78	24	.	.	.
cord-334123-wb45ww7f	79	1	However	however	RB
cord-334123-wb45ww7f	79	2	,	,	,
cord-334123-wb45ww7f	79	3	the	the	DT
cord-334123-wb45ww7f	79	4	double	double	JJ
cord-334123-wb45ww7f	79	5	mutant	mutant	NN
cord-334123-wb45ww7f	79	6	which	which	WDT
cord-334123-wb45ww7f	79	7	combines	combine	VBZ
cord-334123-wb45ww7f	79	8	both	both	DT
cord-334123-wb45ww7f	79	9	changes	change	NNS
cord-334123-wb45ww7f	79	10	restores	restore	VBZ
cord-334123-wb45ww7f	79	11	the	the	DT
cord-334123-wb45ww7f	79	12	putative	putative	JJ
cord-334123-wb45ww7f	79	13	pairing	pairing	NN
cord-334123-wb45ww7f	79	14	and	and	CC
cord-334123-wb45ww7f	79	15	the	the	DT
cord-334123-wb45ww7f	79	16	binding	bind	VBG
cord-334123-wb45ww7f	79	17	affinity	affinity	NN
cord-334123-wb45ww7f	79	18	.	.	.
cord-334123-wb45ww7f	80	1	These	these	DT
cord-334123-wb45ww7f	80	2	and	and	CC
cord-334123-wb45ww7f	80	3	similar	similar	JJ
cord-334123-wb45ww7f	80	4	data	datum	NNS
cord-334123-wb45ww7f	80	5	with	with	IN
cord-334123-wb45ww7f	80	6	over	over	IN
cord-334123-wb45ww7f	80	7	30	30	CD
cord-334123-wb45ww7f	80	8	mutant	mutant	JJ
cord-334123-wb45ww7f	80	9	RNAs	rna	NNS
cord-334123-wb45ww7f	80	10	led	lead	VBD
cord-334123-wb45ww7f	80	11	to	to	IN
cord-334123-wb45ww7f	80	12	a	a	DT
cord-334123-wb45ww7f	80	13	revised	revise	VBN
cord-334123-wb45ww7f	80	14	and	and	CC
cord-334123-wb45ww7f	80	15	more	more	RBR
cord-334123-wb45ww7f	80	16	complex	complex	JJ
cord-334123-wb45ww7f	80	17	structure	structure	NN
cord-334123-wb45ww7f	80	18	which	which	WDT
cord-334123-wb45ww7f	80	19	is	be	VBZ
cord-334123-wb45ww7f	80	20	visualized	visualize	VBN
cord-334123-wb45ww7f	80	21	as	as	IN
cord-334123-wb45ww7f	80	22	a	a	DT
cord-334123-wb45ww7f	80	23	double	double	JJ
cord-334123-wb45ww7f	80	24	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	80	25	.	.	.
cord-334123-wb45ww7f	81	1	To	to	IN
cord-334123-wb45ww7f	81	2	my	-PRON-	PRP$
cord-334123-wb45ww7f	81	3	knowledge	knowledge	NN
cord-334123-wb45ww7f	81	4	this	this	DT
cord-334123-wb45ww7f	81	5	is	be	VBZ
cord-334123-wb45ww7f	81	6	the	the	DT
cord-334123-wb45ww7f	81	7	first	first	JJ
cord-334123-wb45ww7f	81	8	example	example	NN
cord-334123-wb45ww7f	81	9	of	of	IN
cord-334123-wb45ww7f	81	10	the	the	DT
cord-334123-wb45ww7f	81	11	use	use	NN
cord-334123-wb45ww7f	81	12	of	of	IN
cord-334123-wb45ww7f	81	13	direct	direct	JJ
cord-334123-wb45ww7f	81	14	protein	protein	NN
cord-334123-wb45ww7f	81	15	-	-	HYPH
cord-334123-wb45ww7f	81	16	RNA	rna	NN
cord-334123-wb45ww7f	81	17	binding	binding	NN
cord-334123-wb45ww7f	81	18	measurements	measurement	NNS
cord-334123-wb45ww7f	81	19	to	to	TO
cord-334123-wb45ww7f	81	20	define	define	VB
cord-334123-wb45ww7f	81	21	an	an	DT
cord-334123-wb45ww7f	81	22	RNA	RNA	NNP
cord-334123-wb45ww7f	81	23	structure	structure	NN
cord-334123-wb45ww7f	81	24	.	.	.
cord-334123-wb45ww7f	82	1	The	the	DT
cord-334123-wb45ww7f	82	2	changes	change	NNS
cord-334123-wb45ww7f	82	3	in	in	IN
cord-334123-wb45ww7f	82	4	affinity	affinity	NN
cord-334123-wb45ww7f	82	5	that	that	WDT
cord-334123-wb45ww7f	82	6	accompany	accompany	VBP
cord-334123-wb45ww7f	82	7	disruption	disruption	NN
cord-334123-wb45ww7f	82	8	of	of	IN
cord-334123-wb45ww7f	82	9	the	the	DT
cord-334123-wb45ww7f	82	10	proposed	propose	VBN
cord-334123-wb45ww7f	82	11	structure	structure	NN
cord-334123-wb45ww7f	82	12	are	be	VBP
cord-334123-wb45ww7f	82	13	in	in	IN
cord-334123-wb45ww7f	82	14	all	all	DT
cord-334123-wb45ww7f	82	15	cases	case	NNS
cord-334123-wb45ww7f	82	16	relatively	relatively	RB
cord-334123-wb45ww7f	82	17	small	small	JJ
cord-334123-wb45ww7f	82	18	in	in	IN
cord-334123-wb45ww7f	82	19	terms	term	NNS
cord-334123-wb45ww7f	82	20	of	of	IN
cord-334123-wb45ww7f	82	21	binding	bind	VBG
cord-334123-wb45ww7f	82	22	energy	energy	NN
cord-334123-wb45ww7f	82	23	.	.	.
cord-334123-wb45ww7f	83	1	For	for	IN
cord-334123-wb45ww7f	83	2	example	example	NN
cord-334123-wb45ww7f	83	3	,	,	,
cord-334123-wb45ww7f	83	4	many	many	JJ
cord-334123-wb45ww7f	83	5	of	of	IN
cord-334123-wb45ww7f	83	6	the	the	DT
cord-334123-wb45ww7f	83	7	changes	change	NNS
cord-334123-wb45ww7f	83	8	in	in	IN
cord-334123-wb45ww7f	83	9	the	the	DT
cord-334123-wb45ww7f	83	10	S4	S4	NNP
cord-334123-wb45ww7f	83	11	association	association	NN
cord-334123-wb45ww7f	83	12	constant	constant	NN
cord-334123-wb45ww7f	83	13	are	be	VBP
cord-334123-wb45ww7f	83	14	less	less	JJR
cord-334123-wb45ww7f	83	15	than	than	IN
cord-334123-wb45ww7f	83	16	lo	lo	NNP
cord-334123-wb45ww7f	83	17	-	-	HYPH
cord-334123-wb45ww7f	83	18	fold	fold	VB
cord-334123-wb45ww7f	83	19	-	-	HYPH
cord-334123-wb45ww7f	83	20	a	a	DT
cord-334123-wb45ww7f	83	21	change	change	NN
cord-334123-wb45ww7f	83	22	which	which	WDT
cord-334123-wb45ww7f	83	23	itself	-PRON-	PRP
cord-334123-wb45ww7f	83	24	corresponds	correspond	VBZ
cord-334123-wb45ww7f	83	25	to	to	IN
cord-334123-wb45ww7f	83	26	only	only	RB
cord-334123-wb45ww7f	83	27	1.4	1.4	CD
cord-334123-wb45ww7f	83	28	kcal	kcal	NNS
cord-334123-wb45ww7f	83	29	per	per	IN
cord-334123-wb45ww7f	83	30	mole	mole	NN
cord-334123-wb45ww7f	83	31	.	.	.
cord-334123-wb45ww7f	84	1	A	a	DT
cord-334123-wb45ww7f	84	2	change	change	NN
cord-334123-wb45ww7f	84	3	of	of	IN
cord-334123-wb45ww7f	84	4	this	this	DT
cord-334123-wb45ww7f	84	5	magnitude	magnitude	NN
cord-334123-wb45ww7f	84	6	could	could	MD
cord-334123-wb45ww7f	84	7	be	be	VB
cord-334123-wb45ww7f	84	8	due	due	JJ
cord-334123-wb45ww7f	84	9	to	to	IN
cord-334123-wb45ww7f	84	10	perturbation	perturbation	NN
cord-334123-wb45ww7f	84	11	of	of	IN
cord-334123-wb45ww7f	84	12	a	a	DT
cord-334123-wb45ww7f	84	13	van	van	NNP
cord-334123-wb45ww7f	84	14	der	der	NNP
cord-334123-wb45ww7f	84	15	Waals	Waals	NNP
cord-334123-wb45ww7f	84	16	interaction	interaction	NN
cord-334123-wb45ww7f	84	17	.	.	.
cord-334123-wb45ww7f	85	1	There	there	EX
cord-334123-wb45ww7f	85	2	are	be	VBP
cord-334123-wb45ww7f	85	3	no	no	DT
cord-334123-wb45ww7f	85	4	mutations	mutation	NNS
cord-334123-wb45ww7f	85	5	in	in	IN
cord-334123-wb45ww7f	85	6	the	the	DT
cord-334123-wb45ww7f	85	7	proposed	propose	VBN
cord-334123-wb45ww7f	85	8	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	85	9	that	that	WDT
cord-334123-wb45ww7f	85	10	totally	totally	RB
cord-334123-wb45ww7f	85	11	eliminate	eliminate	VBP
cord-334123-wb45ww7f	85	12	binding	binding	NN
cord-334123-wb45ww7f	85	13	and	and	CC
cord-334123-wb45ww7f	85	14	would	would	MD
cord-334123-wb45ww7f	85	15	,	,	,
cord-334123-wb45ww7f	85	16	therefore	therefore	RB
cord-334123-wb45ww7f	85	17	,	,	,
cord-334123-wb45ww7f	85	18	be	be	VB
cord-334123-wb45ww7f	85	19	analogous	analogous	JJ
cord-334123-wb45ww7f	85	20	to	to	TO
cord-334123-wb45ww7f	85	21	point	point	VB
cord-334123-wb45ww7f	85	22	mutations	mutation	NNS
cord-334123-wb45ww7f	85	23	in	in	IN
cord-334123-wb45ww7f	85	24	a	a	DT
cord-334123-wb45ww7f	85	25	tRNA	trna	NN
cord-334123-wb45ww7f	85	26	that	that	WDT
cord-334123-wb45ww7f	85	27	eliminate	eliminate	VBP
cord-334123-wb45ww7f	85	28	aminoacylation	aminoacylation	NN
cord-334123-wb45ww7f	85	29	in	in	IN
cord-334123-wb45ww7f	85	30	vitro	vitro	FW
cord-334123-wb45ww7f	85	31	(	(	-LRB-
cord-334123-wb45ww7f	86	1	Hou	Hou	NNP
cord-334123-wb45ww7f	86	2	and	and	CC
cord-334123-wb45ww7f	86	3	Schimmel	Schimmel	NNP
cord-334123-wb45ww7f	86	4	,	,	,
cord-334123-wb45ww7f	86	5	1988	1988	CD
cord-334123-wb45ww7f	86	6	;	;	:
cord-334123-wb45ww7f	86	7	Schulman	Schulman	NNP
cord-334123-wb45ww7f	86	8	and	and	CC
cord-334123-wb45ww7f	86	9	Pelka	Pelka	NNP
cord-334123-wb45ww7f	86	10	,	,	,
cord-334123-wb45ww7f	86	11	1988	1988	CD
cord-334123-wb45ww7f	86	12	)	)	-RRB-
cord-334123-wb45ww7f	86	13	.	.	.
cord-334123-wb45ww7f	87	1	Possibly	possibly	RB
cord-334123-wb45ww7f	87	2	the	the	DT
cord-334123-wb45ww7f	87	3	most	most	RBS
cord-334123-wb45ww7f	87	4	critical	critical	JJ
cord-334123-wb45ww7f	87	5	nucleotide	nucleotide	JJ
cord-334123-wb45ww7f	87	6	determinants	determinant	NNS
cord-334123-wb45ww7f	87	7	for	for	IN
cord-334123-wb45ww7f	87	8	S4	S4	NNP
cord-334123-wb45ww7f	87	9	recognition	recognition	NN
cord-334123-wb45ww7f	87	10	within	within	IN
cord-334123-wb45ww7f	87	11	the	the	DT
cord-334123-wb45ww7f	87	12	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	87	13	have	have	VBP
cord-334123-wb45ww7f	87	14	not	not	RB
cord-334123-wb45ww7f	87	15	been	be	VBN
cord-334123-wb45ww7f	87	16	identified	identify	VBN
cord-334123-wb45ww7f	87	17	in	in	IN
cord-334123-wb45ww7f	87	18	the	the	DT
cord-334123-wb45ww7f	87	19	mutational	mutational	JJ
cord-334123-wb45ww7f	87	20	analysis	analysis	NN
cord-334123-wb45ww7f	87	21	,	,	,
cord-334123-wb45ww7f	87	22	as	as	IN
cord-334123-wb45ww7f	87	23	they	-PRON-	PRP
cord-334123-wb45ww7f	87	24	have	have	VBP
cord-334123-wb45ww7f	87	25	in	in	IN
cord-334123-wb45ww7f	87	26	the	the	DT
cord-334123-wb45ww7f	87	27	synthetase	synthetase	NN
cord-334123-wb45ww7f	87	28	-	-	HYPH
cord-334123-wb45ww7f	87	29	tRNA	trna	NN
cord-334123-wb45ww7f	87	30	system	system	NN
cord-334123-wb45ww7f	87	31	.	.	.
cord-334123-wb45ww7f	88	1	Alternatively	alternatively	RB
cord-334123-wb45ww7f	88	2	,	,	,
cord-334123-wb45ww7f	88	3	the	the	DT
cord-334123-wb45ww7f	88	4	interactions	interaction	NNS
cord-334123-wb45ww7f	88	5	of	of	IN
cord-334123-wb45ww7f	88	6	a	a	DT
cord-334123-wb45ww7f	88	7	operon	operon	NN
cord-334123-wb45ww7f	88	8	mRNA	mrna	NN
cord-334123-wb45ww7f	88	9	with	with	IN
cord-334123-wb45ww7f	88	10	S4	S4	NNP
cord-334123-wb45ww7f	88	11	may	may	MD
cord-334123-wb45ww7f	88	12	be	be	VB
cord-334123-wb45ww7f	88	13	distributed	distribute	VBN
cord-334123-wb45ww7f	88	14	over	over	IN
cord-334123-wb45ww7f	88	15	many	many	JJ
cord-334123-wb45ww7f	88	16	sites	site	NNS
cord-334123-wb45ww7f	88	17	in	in	IN
cord-334123-wb45ww7f	88	18	the	the	DT
cord-334123-wb45ww7f	88	19	structure	structure	NN
cord-334123-wb45ww7f	88	20	,	,	,
cord-334123-wb45ww7f	88	21	so	so	IN
cord-334123-wb45ww7f	88	22	that	that	IN
cord-334123-wb45ww7f	88	23	any	any	DT
cord-334123-wb45ww7f	88	24	given	give	VBN
cord-334123-wb45ww7f	88	25	alteration	alteration	NN
cord-334123-wb45ww7f	88	26	produces	produce	VBZ
cord-334123-wb45ww7f	88	27	only	only	RB
cord-334123-wb45ww7f	88	28	a	a	DT
cord-334123-wb45ww7f	88	29	small	small	JJ
cord-334123-wb45ww7f	88	30	change	change	NN
cord-334123-wb45ww7f	88	31	in	in	IN
cord-334123-wb45ww7f	88	32	affinity	affinity	NN
cord-334123-wb45ww7f	88	33	.	.	.
cord-334123-wb45ww7f	89	1	It	-PRON-	PRP
cord-334123-wb45ww7f	89	2	is	be	VBZ
cord-334123-wb45ww7f	89	3	noteworthy	noteworthy	JJ
cord-334123-wb45ww7f	89	4	that	that	IN
cord-334123-wb45ww7f	89	5	one	one	CD
cord-334123-wb45ww7f	89	6	of	of	IN
cord-334123-wb45ww7f	89	7	the	the	DT
cord-334123-wb45ww7f	89	8	mutations	mutation	NNS
cord-334123-wb45ww7f	89	9	that	that	WDT
cord-334123-wb45ww7f	89	10	disrupts	disrupt	VBZ
cord-334123-wb45ww7f	89	11	a	a	DT
cord-334123-wb45ww7f	89	12	base	base	NN
cord-334123-wb45ww7f	89	13	pair	pair	NN
cord-334123-wb45ww7f	89	14	in	in	IN
cord-334123-wb45ww7f	89	15	the	the	DT
cord-334123-wb45ww7f	89	16	proposed	propose	VBN
cord-334123-wb45ww7f	89	17	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	89	18	structure	structure	NN
cord-334123-wb45ww7f	89	19	can	can	MD
cord-334123-wb45ww7f	89	20	not	not	RB
cord-334123-wb45ww7f	89	21	be	be	VB
cord-334123-wb45ww7f	89	22	rescued	rescue	VBN
cord-334123-wb45ww7f	89	23	by	by	IN
cord-334123-wb45ww7f	89	24	a	a	DT
cord-334123-wb45ww7f	89	25	second	second	JJ
cord-334123-wb45ww7f	89	26	site	site	NN
cord-334123-wb45ww7f	89	27	mutation	mutation	NN
cord-334123-wb45ww7f	89	28	which	which	WDT
cord-334123-wb45ww7f	89	29	restores	restore	VBZ
cord-334123-wb45ww7f	89	30	pairing	pair	VBG
cord-334123-wb45ww7f	89	31	.	.	.
cord-334123-wb45ww7f	90	1	This	this	DT
cord-334123-wb45ww7f	90	2	could	could	MD
cord-334123-wb45ww7f	90	3	be	be	VB
cord-334123-wb45ww7f	90	4	a	a	DT
cord-334123-wb45ww7f	90	5	site	site	NN
cord-334123-wb45ww7f	90	6	where	where	WRB
cord-334123-wb45ww7f	90	7	S4	S4	NNP
cord-334123-wb45ww7f	90	8	interacts	interact	VBZ
cord-334123-wb45ww7f	90	9	directly	directly	RB
cord-334123-wb45ww7f	90	10	with	with	IN
cord-334123-wb45ww7f	90	11	a	a	DT
cord-334123-wb45ww7f	90	12	specific	specific	JJ
cord-334123-wb45ww7f	90	13	base	base	NN
cord-334123-wb45ww7f	90	14	pair	pair	NN
cord-334123-wb45ww7f	90	15	,	,	,
cord-334123-wb45ww7f	90	16	and	and	CC
cord-334123-wb45ww7f	90	17	contributes	contribute	VBZ
cord-334123-wb45ww7f	90	18	a	a	DT
cord-334123-wb45ww7f	90	19	small	small	JJ
cord-334123-wb45ww7f	90	20	incremental	incremental	JJ
cord-334123-wb45ww7f	90	21	stability	stability	NN
cord-334123-wb45ww7f	90	22	to	to	IN
cord-334123-wb45ww7f	90	23	the	the	DT
cord-334123-wb45ww7f	90	24	complex	complex	NN
cord-334123-wb45ww7f	90	25	.	.	.
cord-334123-wb45ww7f	91	1	Ongoing	ongoing	JJ
cord-334123-wb45ww7f	91	2	experiments	experiment	NNS
cord-334123-wb45ww7f	91	3	will	will	MD
cord-334123-wb45ww7f	91	4	assess	assess	VB
cord-334123-wb45ww7f	91	5	the	the	DT
cord-334123-wb45ww7f	91	6	relationship	relationship	NN
cord-334123-wb45ww7f	91	7	between	between	IN
cord-334123-wb45ww7f	91	8	alterations	alteration	NNS
cord-334123-wb45ww7f	91	9	that	that	WDT
cord-334123-wb45ww7f	91	10	disrupt	disrupt	VBP
cord-334123-wb45ww7f	91	11	the	the	DT
cord-334123-wb45ww7f	91	12	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	91	13	-	-	HYPH
cord-334123-wb45ww7f	91	14	dependent	dependent	JJ
cord-334123-wb45ww7f	91	15	protein	protein	NN
cord-334123-wb45ww7f	91	16	-	-	HYPH
cord-334123-wb45ww7f	91	17	RNA	rna	NN
cord-334123-wb45ww7f	91	18	interaction	interaction	NN
cord-334123-wb45ww7f	91	19	in	in	IN
cord-334123-wb45ww7f	91	20	vitro	vitro	FW
cord-334123-wb45ww7f	91	21	and	and	CC
cord-334123-wb45ww7f	91	22	the	the	DT
cord-334123-wb45ww7f	91	23	extent	extent	NN
cord-334123-wb45ww7f	91	24	of	of	IN
cord-334123-wb45ww7f	91	25	translational	translational	JJ
cord-334123-wb45ww7f	91	26	repression	repression	NN
cord-334123-wb45ww7f	91	27	in	in	IN
cord-334123-wb45ww7f	91	28	vivo	vivo	NN
cord-334123-wb45ww7f	91	29	.	.	.
cord-334123-wb45ww7f	92	1	Regardless	regardless	RB
cord-334123-wb45ww7f	92	2	of	of	IN
cord-334123-wb45ww7f	92	3	the	the	DT
cord-334123-wb45ww7f	92	4	detailed	detailed	JJ
cord-334123-wb45ww7f	92	5	interpretation	interpretation	NN
cord-334123-wb45ww7f	92	6	of	of	IN
cord-334123-wb45ww7f	92	7	the	the	DT
cord-334123-wb45ww7f	92	8	experiments	experiment	NNS
cord-334123-wb45ww7f	92	9	,	,	,
cord-334123-wb45ww7f	92	10	the	the	DT
cord-334123-wb45ww7f	92	11	analysis	analysis	NN
cord-334123-wb45ww7f	92	12	of	of	IN
cord-334123-wb45ww7f	92	13	RNA	RNA	NNP
cord-334123-wb45ww7f	92	14	structure	structure	NN
cord-334123-wb45ww7f	92	15	by	by	IN
cord-334123-wb45ww7f	92	16	these	these	DT
cord-334123-wb45ww7f	92	17	methods	method	NNS
cord-334123-wb45ww7f	92	18	is	be	VBZ
cord-334123-wb45ww7f	92	19	instructive	instructive	JJ
cord-334123-wb45ww7f	92	20	and	and	CC
cord-334123-wb45ww7f	92	21	has	have	VBZ
cord-334123-wb45ww7f	92	22	provided	provide	VBN
cord-334123-wb45ww7f	92	23	one	one	CD
cord-334123-wb45ww7f	92	24	of	of	IN
cord-334123-wb45ww7f	92	25	the	the	DT
cord-334123-wb45ww7f	92	26	first	first	JJ
cord-334123-wb45ww7f	92	27	examples	example	NNS
cord-334123-wb45ww7f	92	28	of	of	IN
cord-334123-wb45ww7f	92	29	a	a	DT
cord-334123-wb45ww7f	92	30	functional	functional	JJ
cord-334123-wb45ww7f	92	31	probe	probe	NN
cord-334123-wb45ww7f	92	32	for	for	IN
cord-334123-wb45ww7f	92	33	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	92	34	formation	formation	NN
cord-334123-wb45ww7f	92	35	.	.	.
cord-334123-wb45ww7f	93	1	The	the	DT
cord-334123-wb45ww7f	93	2	second	second	JJ
cord-334123-wb45ww7f	93	3	study	study	NN
cord-334123-wb45ww7f	93	4	provides	provide	VBZ
cord-334123-wb45ww7f	93	5	evidence	evidence	NN
cord-334123-wb45ww7f	93	6	that	that	IN
cord-334123-wb45ww7f	93	7	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	93	8	formation	formation	NN
cord-334123-wb45ww7f	93	9	in	in	IN
cord-334123-wb45ww7f	93	10	a	a	DT
cord-334123-wb45ww7f	93	11	viral	viral	JJ
cord-334123-wb45ww7f	93	12	mRNA	mrna	NN
cord-334123-wb45ww7f	93	13	is	be	VBZ
cord-334123-wb45ww7f	93	14	required	require	VBN
cord-334123-wb45ww7f	93	15	for	for	IN
cord-334123-wb45ww7f	93	16	frameshift	frameshift	NN
cord-334123-wb45ww7f	93	17	suppression	suppression	NN
cord-334123-wb45ww7f	93	18	of	of	IN
cord-334123-wb45ww7f	93	19	a	a	DT
cord-334123-wb45ww7f	93	20	termination	termination	NN
cord-334123-wb45ww7f	93	21	codon	codon	NN
cord-334123-wb45ww7f	93	22	that	that	IN
cord-334123-wb45ww7f	93	23	,	,	,
cord-334123-wb45ww7f	93	24	in	in	IN
cord-334123-wb45ww7f	93	25	turn	turn	NN
cord-334123-wb45ww7f	93	26	,	,	,
cord-334123-wb45ww7f	93	27	allows	allow	VBZ
cord-334123-wb45ww7f	93	28	a	a	DT
cord-334123-wb45ww7f	93	29	fusion	fusion	NN
cord-334123-wb45ww7f	93	30	protein	protein	NN
cord-334123-wb45ww7f	93	31	to	to	TO
cord-334123-wb45ww7f	93	32	be	be	VB
cord-334123-wb45ww7f	93	33	synthesized	synthesize	VBN
cord-334123-wb45ww7f	93	34	from	from	IN
cord-334123-wb45ww7f	93	35	two	two	CD
cord-334123-wb45ww7f	93	36	overlapping	overlap	VBG
cord-334123-wb45ww7f	93	37	reading	reading	NN
cord-334123-wb45ww7f	93	38	frames	frame	NNS
cord-334123-wb45ww7f	93	39	.	.	.
cord-334123-wb45ww7f	94	1	Earlier	early	JJR
cord-334123-wb45ww7f	94	2	work	work	NN
cord-334123-wb45ww7f	94	3	had	have	VBD
cord-334123-wb45ww7f	94	4	demonstrated	demonstrate	VBN
cord-334123-wb45ww7f	94	5	a	a	DT
cord-334123-wb45ww7f	94	6	role	role	NN
cord-334123-wb45ww7f	94	7	for	for	IN
cord-334123-wb45ww7f	94	8	frameshifting	frameshifte	VBG
cord-334123-wb45ww7f	94	9	in	in	IN
cord-334123-wb45ww7f	94	10	the	the	DT
cord-334123-wb45ww7f	94	11	production	production	NN
cord-334123-wb45ww7f	94	12	of	of	IN
cord-334123-wb45ww7f	94	13	some	some	DT
cord-334123-wb45ww7f	94	14	retroviral	retroviral	JJ
cord-334123-wb45ww7f	94	15	gag	gag	NN
cord-334123-wb45ww7f	94	16	-	-	HYPH
cord-334123-wb45ww7f	94	17	pol	pol	NN
cord-334123-wb45ww7f	94	18	or	or	CC
cord-334123-wb45ww7f	94	19	gag	gag	NN
cord-334123-wb45ww7f	94	20	-	-	HYPH
cord-334123-wb45ww7f	94	21	pro	pro	JJ
cord-334123-wb45ww7f	94	22	-	-	JJ
cord-334123-wb45ww7f	94	23	pol	pol	JJ
cord-334123-wb45ww7f	94	24	fusion	fusion	NN
cord-334123-wb45ww7f	94	25	proteins	protein	NNS
cord-334123-wb45ww7f	94	26	(	(	-LRB-
cord-334123-wb45ww7f	94	27	Jacks	Jacks	NNPS
cord-334123-wb45ww7f	94	28	et	et	NNP
cord-334123-wb45ww7f	94	29	al	al	NNP
cord-334123-wb45ww7f	94	30	.	.	NNP
cord-334123-wb45ww7f	94	31	,	,	,
cord-334123-wb45ww7f	94	32	1988	1988	CD
cord-334123-wb45ww7f	94	33	;	;	:
cord-334123-wb45ww7f	94	34	Wilson	Wilson	NNP
cord-334123-wb45ww7f	94	35	et	et	NNP
cord-334123-wb45ww7f	94	36	al	al	NNP
cord-334123-wb45ww7f	94	37	.	.	NNP
cord-334123-wb45ww7f	94	38	,	,	,
cord-334123-wb45ww7f	94	39	1988	1988	CD
cord-334123-wb45ww7f	94	40	,	,	,
cord-334123-wb45ww7f	94	41	and	and	CC
cord-334123-wb45ww7f	94	42	references	reference	NNS
cord-334123-wb45ww7f	94	43	therein	therein	RB
cord-334123-wb45ww7f	94	44	)	)	-RRB-
cord-334123-wb45ww7f	94	45	.	.	.
cord-334123-wb45ww7f	95	1	Most	most	RBS
cord-334123-wb45ww7f	95	2	commonly	commonly	RB
cord-334123-wb45ww7f	95	3	,	,	,
cord-334123-wb45ww7f	95	4	termination	termination	NN
cord-334123-wb45ww7f	95	5	occurs	occur	VBZ
cord-334123-wb45ww7f	95	6	at	at	IN
cord-334123-wb45ww7f	95	7	the	the	DT
cord-334123-wb45ww7f	95	8	gag	gag	NN
cord-334123-wb45ww7f	95	9	stop	stop	NN
cord-334123-wb45ww7f	95	10	codon	codon	NN
cord-334123-wb45ww7f	95	11	to	to	TO
cord-334123-wb45ww7f	95	12	yield	yield	VB
cord-334123-wb45ww7f	95	13	virus	virus	NN
cord-334123-wb45ww7f	95	14	core	core	NN
cord-334123-wb45ww7f	95	15	protein	protein	NN
cord-334123-wb45ww7f	95	16	.	.	.
cord-334123-wb45ww7f	96	1	Occasional	occasional	JJ
cord-334123-wb45ww7f	96	2	"	"	``
cord-334123-wb45ww7f	96	3	-1	-1	JJ
cord-334123-wb45ww7f	96	4	"	"	''
cord-334123-wb45ww7f	96	5	frameshifting	frameshifting	JJ
cord-334123-wb45ww7f	96	6	and	and	CC
cord-334123-wb45ww7f	96	7	subsequent	subsequent	JJ
cord-334123-wb45ww7f	96	8	cleavage	cleavage	NN
cord-334123-wb45ww7f	96	9	of	of	IN
cord-334123-wb45ww7f	96	10	the	the	DT
cord-334123-wb45ww7f	96	11	resulting	result	VBG
cord-334123-wb45ww7f	96	12	fusion	fusion	NN
cord-334123-wb45ww7f	96	13	protein	protein	NN
cord-334123-wb45ww7f	96	14	is	be	VBZ
cord-334123-wb45ww7f	96	15	the	the	DT
cord-334123-wb45ww7f	96	16	mechanism	mechanism	NN
cord-334123-wb45ww7f	96	17	for	for	IN
cord-334123-wb45ww7f	96	18	production	production	NN
cord-334123-wb45ww7f	96	19	of	of	IN
cord-334123-wb45ww7f	96	20	the	the	DT
cord-334123-wb45ww7f	96	21	viral	viral	JJ
cord-334123-wb45ww7f	96	22	reverse	reverse	NN
cord-334123-wb45ww7f	96	23	transcriptase	transcriptase	NN
cord-334123-wb45ww7f	96	24	(	(	-LRB-
cord-334123-wb45ww7f	96	25	a	a	DT
cord-334123-wb45ww7f	96	26	pol	pol	NN
cord-334123-wb45ww7f	96	27	gene	gene	NN
cord-334123-wb45ww7f	96	28	product	product	NN
cord-334123-wb45ww7f	96	29	)	)	-RRB-
cord-334123-wb45ww7f	96	30	.	.	.
cord-334123-wb45ww7f	97	1	Frameshift	frameshift	NN
cord-334123-wb45ww7f	97	2	mechanisms	mechanism	NNS
cord-334123-wb45ww7f	97	3	may	may	MD
cord-334123-wb45ww7f	97	4	also	also	RB
cord-334123-wb45ww7f	97	5	be	be	VB
cord-334123-wb45ww7f	97	6	operative	operative	JJ
cord-334123-wb45ww7f	97	7	in	in	IN
cord-334123-wb45ww7f	97	8	the	the	DT
cord-334123-wb45ww7f	97	9	production	production	NN
cord-334123-wb45ww7f	97	10	of	of	IN
cord-334123-wb45ww7f	97	11	reverse	reverse	JJ
cord-334123-wb45ww7f	97	12	transcriptases	transcriptase	NNS
cord-334123-wb45ww7f	97	13	encoded	encode	VBN
cord-334123-wb45ww7f	97	14	by	by	IN
cord-334123-wb45ww7f	97	15	retrotransposons	retrotransposon	NNS
cord-334123-wb45ww7f	97	16	in	in	IN
cord-334123-wb45ww7f	97	17	yeast	yeast	NN
cord-334123-wb45ww7f	97	18	(	(	-LRB-
cord-334123-wb45ww7f	97	19	e.g.	e.g.	RB
cord-334123-wb45ww7f	97	20	,	,	,
cord-334123-wb45ww7f	97	21	Clare	Clare	NNP
cord-334123-wb45ww7f	97	22	et	et	NNP
cord-334123-wb45ww7f	97	23	al	al	NNP
cord-334123-wb45ww7f	97	24	.	.	NNP
cord-334123-wb45ww7f	97	25	,	,	,
cord-334123-wb45ww7f	97	26	1988	1988	CD
cord-334123-wb45ww7f	97	27	)	)	-RRB-
cord-334123-wb45ww7f	97	28	and	and	CC
cord-334123-wb45ww7f	97	29	Drosophila	Drosophila	NNP
cord-334123-wb45ww7f	97	30	(	(	-LRB-
cord-334123-wb45ww7f	97	31	e.g.	e.g.	RB
cord-334123-wb45ww7f	97	32	,	,	,
cord-334123-wb45ww7f	97	33	Marlor	Marlor	NNP
cord-334123-wb45ww7f	97	34	et	et	NNP
cord-334123-wb45ww7f	97	35	al	al	NNP
cord-334123-wb45ww7f	97	36	.	.	NNP
cord-334123-wb45ww7f	97	37	,	,	,
cord-334123-wb45ww7f	97	38	1986	1986	CD
cord-334123-wb45ww7f	97	39	)	)	-RRB-
cord-334123-wb45ww7f	97	40	.	.	.
cord-334123-wb45ww7f	98	1	Varmus	Varmus	NNP
cord-334123-wb45ww7f	98	2	and	and	CC
cord-334123-wb45ww7f	98	3	co	co	NNS
cord-334123-wb45ww7f	98	4	-	-	NNS
cord-334123-wb45ww7f	98	5	workers	worker	NNS
cord-334123-wb45ww7f	98	6	established	establish	VBN
cord-334123-wb45ww7f	98	7	that	that	IN
cord-334123-wb45ww7f	98	8	,	,	,
cord-334123-wb45ww7f	98	9	in	in	IN
cord-334123-wb45ww7f	98	10	Rous	rous	JJ
cord-334123-wb45ww7f	98	11	sarcoma	sarcoma	NN
cord-334123-wb45ww7f	98	12	virus	virus	NN
cord-334123-wb45ww7f	98	13	mRNA	mrna	NN
cord-334123-wb45ww7f	98	14	,	,	,
cord-334123-wb45ww7f	98	15	only	only	RB
cord-334123-wb45ww7f	98	16	147	147	CD
cord-334123-wb45ww7f	98	17	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	98	18	that	that	WDT
cord-334123-wb45ww7f	98	19	encode	encode	VBP
cord-334123-wb45ww7f	98	20	the	the	DT
cord-334123-wb45ww7f	98	21	site	site	NN
cord-334123-wb45ww7f	98	22	for	for	IN
cord-334123-wb45ww7f	98	23	frameshifting	frameshifte	VBG
cord-334123-wb45ww7f	98	24	are	be	VBP
cord-334123-wb45ww7f	98	25	necessary	necessary	JJ
cord-334123-wb45ww7f	99	1	(	(	-LRB-
cord-334123-wb45ww7f	99	2	Jacks	Jacks	NNP
cord-334123-wb45ww7f	99	3	et	et	NNP
cord-334123-wb45ww7f	99	4	al	al	NNP
cord-334123-wb45ww7f	99	5	.	.	NNP
cord-334123-wb45ww7f	99	6	,	,	,
cord-334123-wb45ww7f	99	7	1988	1988	CD
cord-334123-wb45ww7f	99	8	)	)	-RRB-
cord-334123-wb45ww7f	99	9	.	.	.
cord-334123-wb45ww7f	100	1	The	the	DT
cord-334123-wb45ww7f	100	2	sequence	sequence	NN
cord-334123-wb45ww7f	100	3	at	at	IN
cord-334123-wb45ww7f	100	4	the	the	DT
cord-334123-wb45ww7f	100	5	frameshift	frameshift	NN
cord-334123-wb45ww7f	100	6	site	site	NN
cord-334123-wb45ww7f	100	7	is	be	VBZ
cord-334123-wb45ww7f	100	8	A	a	DT
cord-334123-wb45ww7f	100	9	AAU	AAU	NNP
cord-334123-wb45ww7f	100	10	UUA	UUA	NNP
cord-334123-wb45ww7f	100	11	,	,	,
cord-334123-wb45ww7f	100	12	where	where	WRB
cord-334123-wb45ww7f	100	13	the	the	DT
cord-334123-wb45ww7f	100	14	"	"	``
cord-334123-wb45ww7f	100	15	0	0	NFP
cord-334123-wb45ww7f	100	16	"	"	''
cord-334123-wb45ww7f	100	17	reading	reading	NN
cord-334123-wb45ww7f	100	18	frame	frame	NN
cord-334123-wb45ww7f	100	19	is	be	VBZ
cord-334123-wb45ww7f	100	20	indicated	indicate	VBN
cord-334123-wb45ww7f	100	21	.	.	.
cord-334123-wb45ww7f	101	1	Operationally	operationally	RB
cord-334123-wb45ww7f	101	2	there	there	EX
cord-334123-wb45ww7f	101	3	is	be	VBZ
cord-334123-wb45ww7f	101	4	simultaneous	simultaneous	JJ
cord-334123-wb45ww7f	101	5	-1	-1	NN
cord-334123-wb45ww7f	101	6	slippage	slippage	NN
cord-334123-wb45ww7f	101	7	of	of	IN
cord-334123-wb45ww7f	101	8	a	a	DT
cord-334123-wb45ww7f	101	9	UUA	UUA	NNP
cord-334123-wb45ww7f	101	10	-	-	HYPH
cord-334123-wb45ww7f	101	11	reading	reading	NN
cord-334123-wb45ww7f	101	12	tRNALeU	tRNALeU	NNS
cord-334123-wb45ww7f	101	13	(	(	-LRB-
cord-334123-wb45ww7f	101	14	bound	bind	VBN
cord-334123-wb45ww7f	101	15	to	to	IN
cord-334123-wb45ww7f	101	16	the	the	DT
cord-334123-wb45ww7f	101	17	ribosomal	ribosomal	JJ
cord-334123-wb45ww7f	101	18	A	a	NN
cord-334123-wb45ww7f	101	19	-	-	HYPH
cord-334123-wb45ww7f	101	20	site	site	NN
cord-334123-wb45ww7f	101	21	)	)	-RRB-
cord-334123-wb45ww7f	101	22	and	and	CC
cord-334123-wb45ww7f	101	23	an	an	DT
cord-334123-wb45ww7f	101	24	AA&reading	aa&reade	VBG
cord-334123-wb45ww7f	101	25	tRNAAsn	tRNAAsn	NNP
cord-334123-wb45ww7f	101	26	(	(	-LRB-
cord-334123-wb45ww7f	101	27	bound	bind	VBN
cord-334123-wb45ww7f	101	28	to	to	IN
cord-334123-wb45ww7f	101	29	the	the	DT
cord-334123-wb45ww7f	101	30	P	p	NN
cord-334123-wb45ww7f	101	31	-	-	HYPH
cord-334123-wb45ww7f	101	32	site	site	NN
cord-334123-wb45ww7f	101	33	)	)	-RRB-
cord-334123-wb45ww7f	101	34	,	,	,
cord-334123-wb45ww7f	101	35	which	which	WDT
cord-334123-wb45ww7f	101	36	results	result	VBZ
cord-334123-wb45ww7f	101	37	in	in	IN
cord-334123-wb45ww7f	101	38	a	a	DT
cord-334123-wb45ww7f	101	39	double	double	JJ
cord-334123-wb45ww7f	101	40	frameshift	frameshift	NN
cord-334123-wb45ww7f	101	41	.	.	.
cord-334123-wb45ww7f	102	1	In	in	IN
cord-334123-wb45ww7f	102	2	the	the	DT
cord-334123-wb45ww7f	102	3	-1	-1	NN
cord-334123-wb45ww7f	102	4	position	position	NN
cord-334123-wb45ww7f	102	5	these	these	DT
cord-334123-wb45ww7f	102	6	tRNAs	trna	NNS
cord-334123-wb45ww7f	102	7	are	be	VBP
cord-334123-wb45ww7f	102	8	proposed	propose	VBN
cord-334123-wb45ww7f	102	9	to	to	TO
cord-334123-wb45ww7f	102	10	read	read	VB
cord-334123-wb45ww7f	102	11	their	-PRON-	PRP$
cord-334123-wb45ww7f	102	12	respective	respective	JJ
cord-334123-wb45ww7f	102	13	codons	codon	NNS
cord-334123-wb45ww7f	102	14	by	by	IN
cord-334123-wb45ww7f	102	15	two	two	CD
cord-334123-wb45ww7f	102	16	instead	instead	RB
cord-334123-wb45ww7f	102	17	of	of	IN
cord-334123-wb45ww7f	102	18	three	three	CD
cord-334123-wb45ww7f	102	19	bases	basis	NNS
cord-334123-wb45ww7f	102	20	.	.	.
cord-334123-wb45ww7f	103	1	Slippage	slippage	NN
cord-334123-wb45ww7f	103	2	of	of	IN
cord-334123-wb45ww7f	103	3	these	these	DT
cord-334123-wb45ww7f	103	4	tRNAs	trna	NNS
cord-334123-wb45ww7f	103	5	is	be	VBZ
cord-334123-wb45ww7f	103	6	dependent	dependent	JJ
cord-334123-wb45ww7f	103	7	on	on	IN
cord-334123-wb45ww7f	103	8	the	the	DT
cord-334123-wb45ww7f	103	9	formation	formation	NN
cord-334123-wb45ww7f	103	10	of	of	IN
cord-334123-wb45ww7f	103	11	a	a	DT
cord-334123-wb45ww7f	103	12	hairpin	hairpin	JJ
cord-334123-wb45ww7f	103	13	stem	stem	NN
cord-334123-wb45ww7f	103	14	-	-	HYPH
cord-334123-wb45ww7f	103	15	loop	loop	NN
cord-334123-wb45ww7f	103	16	structure	structure	NN
cord-334123-wb45ww7f	103	17	that	that	WDT
cord-334123-wb45ww7f	103	18	is	be	VBZ
cord-334123-wb45ww7f	103	19	immediately	immediately	RB
cord-334123-wb45ww7f	103	20	downstream	downstream	JJ
cord-334123-wb45ww7f	103	21	.	.	.
cord-334123-wb45ww7f	104	1	Thus	thus	RB
cord-334123-wb45ww7f	104	2	,	,	,
cord-334123-wb45ww7f	104	3	in	in	IN
cord-334123-wb45ww7f	104	4	addition	addition	NN
cord-334123-wb45ww7f	104	5	to	to	IN
cord-334123-wb45ww7f	104	6	other	other	JJ
cord-334123-wb45ww7f	104	7	possible	possible	JJ
cord-334123-wb45ww7f	104	8	mechanisms	mechanism	NNS
cord-334123-wb45ww7f	104	9	(	(	-LRB-
cord-334123-wb45ww7f	104	10	see	see	VB
cord-334123-wb45ww7f	104	11	Wilson	Wilson	NNP
cord-334123-wb45ww7f	104	12	et	et	NNP
cord-334123-wb45ww7f	104	13	al	al	NNP
cord-334123-wb45ww7f	104	14	.	.	NNP
cord-334123-wb45ww7f	104	15	,	,	,
cord-334123-wb45ww7f	104	16	1988	1988	CD
cord-334123-wb45ww7f	104	17	)	)	-RRB-
cord-334123-wb45ww7f	105	1	this	this	DT
cord-334123-wb45ww7f	105	2	work	work	NN
cord-334123-wb45ww7f	105	3	established	establish	VBD
cord-334123-wb45ww7f	105	4	that	that	IN
cord-334123-wb45ww7f	105	5	-1	-1	NN
cord-334123-wb45ww7f	105	6	frameshifting	frameshifting	NN
cord-334123-wb45ww7f	105	7	can	can	MD
cord-334123-wb45ww7f	105	8	be	be	VB
cord-334123-wb45ww7f	105	9	promoted	promote	VBN
cord-334123-wb45ww7f	105	10	by	by	IN
cord-334123-wb45ww7f	105	11	mRNA	mRNA	NNP
cord-334123-wb45ww7f	105	12	secondary	secondary	JJ
cord-334123-wb45ww7f	105	13	structure	structure	NN
cord-334123-wb45ww7f	105	14	.	.	.
cord-334123-wb45ww7f	106	1	The	the	DT
cord-334123-wb45ww7f	106	2	work	work	NN
cord-334123-wb45ww7f	106	3	of	of	IN
cord-334123-wb45ww7f	106	4	Brierley	Brierley	NNP
cord-334123-wb45ww7f	106	5	et	et	NNP
cord-334123-wb45ww7f	106	6	al	al	NNP
cord-334123-wb45ww7f	106	7	.	.	.
cord-334123-wb45ww7f	107	1	(	(	-LRB-
cord-334123-wb45ww7f	107	2	1969	1969	CD
cord-334123-wb45ww7f	107	3	)	)	-RRB-
cord-334123-wb45ww7f	107	4	is	be	VBZ
cord-334123-wb45ww7f	107	5	based	base	VBN
cord-334123-wb45ww7f	107	6	on	on	IN
cord-334123-wb45ww7f	107	7	studies	study	NNS
cord-334123-wb45ww7f	107	8	of	of	IN
cord-334123-wb45ww7f	107	9	a	a	DT
cord-334123-wb45ww7f	107	10	nonretroviral	nonretroviral	JJ
cord-334123-wb45ww7f	107	11	system	system	NN
cord-334123-wb45ww7f	107	12	,	,	,
cord-334123-wb45ww7f	107	13	avian	avian	JJ
cord-334123-wb45ww7f	107	14	coronavirus	coronavirus	NN
cord-334123-wb45ww7f	107	15	infectious	infectious	JJ
cord-334123-wb45ww7f	107	16	bronchitis	bronchitis	NN
cord-334123-wb45ww7f	107	17	virus	virus	NN
cord-334123-wb45ww7f	107	18	(	(	-LRB-
cord-334123-wb45ww7f	107	19	IBV	IBV	NNP
cord-334123-wb45ww7f	107	20	)	)	-RRB-
cord-334123-wb45ww7f	107	21	.	.	.
cord-334123-wb45ww7f	108	1	Two	two	CD
cord-334123-wb45ww7f	108	2	long	long	RB
cord-334123-wb45ww7f	108	3	open	open	JJ
cord-334123-wb45ww7f	108	4	reading	reading	NN
cord-334123-wb45ww7f	108	5	frames	frame	NNS
cord-334123-wb45ww7f	108	6	overlap	overlap	VBP
cord-334123-wb45ww7f	108	7	by	by	IN
cord-334123-wb45ww7f	108	8	42	42	CD
cord-334123-wb45ww7f	108	9	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	108	10	,	,	,
cord-334123-wb45ww7f	108	11	with	with	IN
cord-334123-wb45ww7f	108	12	the	the	DT
cord-334123-wb45ww7f	108	13	second	second	JJ
cord-334123-wb45ww7f	108	14	frame	frame	NN
cord-334123-wb45ww7f	108	15	shifted	shift	VBN
cord-334123-wb45ww7f	108	16	by	by	IN
cord-334123-wb45ww7f	108	17	-1	-1	NN
cord-334123-wb45ww7f	108	18	relative	relative	NN
cord-334123-wb45ww7f	108	19	to	to	IN
cord-334123-wb45ww7f	108	20	the	the	DT
cord-334123-wb45ww7f	108	21	first	first	JJ
cord-334123-wb45ww7f	108	22	.	.	.
cord-334123-wb45ww7f	109	1	A	a	DT
cord-334123-wb45ww7f	109	2	-1	-1	NN
cord-334123-wb45ww7f	110	1	frameshift	frameshift	NN
cord-334123-wb45ww7f	110	2	results	result	NNS
cord-334123-wb45ww7f	110	3	in	in	IN
cord-334123-wb45ww7f	110	4	the	the	DT
cord-334123-wb45ww7f	110	5	production	production	NN
cord-334123-wb45ww7f	110	6	of	of	IN
cord-334123-wb45ww7f	110	7	a	a	DT
cord-334123-wb45ww7f	110	8	fusion	fusion	NN
cord-334123-wb45ww7f	110	9	protein	protein	NN
cord-334123-wb45ww7f	110	10	.	.	.
cord-334123-wb45ww7f	111	1	An	an	DT
cord-334123-wb45ww7f	111	2	86	86	CD
cord-334123-wb45ww7f	111	3	nucleotide	nucleotide	JJ
cord-334123-wb45ww7f	111	4	element	element	NN
cord-334123-wb45ww7f	111	5	that	that	WDT
cord-334123-wb45ww7f	111	6	spans	span	VBZ
cord-334123-wb45ww7f	111	7	the	the	DT
cord-334123-wb45ww7f	111	8	overlap	overlap	NN
cord-334123-wb45ww7f	111	9	region	region	NN
cord-334123-wb45ww7f	111	10	is	be	VBZ
cord-334123-wb45ww7f	111	11	sufficient	sufficient	JJ
cord-334123-wb45ww7f	111	12	to	to	TO
cord-334123-wb45ww7f	111	13	promote	promote	VB
cord-334123-wb45ww7f	111	14	frameshifting	frameshifting	NN
cord-334123-wb45ww7f	111	15	,	,	,
cord-334123-wb45ww7f	111	16	even	even	RB
cord-334123-wb45ww7f	111	17	in	in	IN
cord-334123-wb45ww7f	111	18	a	a	DT
cord-334123-wb45ww7f	111	19	heterologous	heterologous	JJ
cord-334123-wb45ww7f	111	20	context	context	NN
cord-334123-wb45ww7f	111	21	.	.	.
cord-334123-wb45ww7f	112	1	This	this	DT
cord-334123-wb45ww7f	112	2	element	element	NN
cord-334123-wb45ww7f	112	3	encodes	encode	VBZ
cord-334123-wb45ww7f	112	4	a	a	DT
cord-334123-wb45ww7f	112	5	stem	stem	NN
cord-334123-wb45ww7f	112	6	-	-	HYPH
cord-334123-wb45ww7f	112	7	loop	loop	NN
cord-334123-wb45ww7f	112	8	structure	structure	NN
cord-334123-wb45ww7f	112	9	that	that	WDT
cord-334123-wb45ww7f	112	10	starts	start	VBZ
cord-334123-wb45ww7f	112	11	six	six	CD
cord-334123-wb45ww7f	112	12	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	112	13	downstream	downstream	JJ
cord-334123-wb45ww7f	112	14	from	from	IN
cord-334123-wb45ww7f	112	15	the	the	DT
cord-334123-wb45ww7f	112	16	proposed	propose	VBN
cord-334123-wb45ww7f	112	17	site	site	NN
cord-334123-wb45ww7f	112	18	of	of	IN
cord-334123-wb45ww7f	112	19	frameshifting	frameshifting	NN
cord-334123-wb45ww7f	112	20	,	,	,
cord-334123-wb45ww7f	112	21	near	near	IN
cord-334123-wb45ww7f	112	22	the	the	DT
cord-334123-wb45ww7f	112	23	end	end	NN
cord-334123-wb45ww7f	112	24	of	of	IN
cord-334123-wb45ww7f	112	25	the	the	DT
cord-334123-wb45ww7f	112	26	first	first	JJ
cord-334123-wb45ww7f	112	27	reading	reading	NN
cord-334123-wb45ww7f	112	28	frame	frame	NN
cord-334123-wb45ww7f	112	29	.	.	.
cord-334123-wb45ww7f	113	1	Located	locate	VBN
cord-334123-wb45ww7f	113	2	30	30	CD
cord-334123-wb45ww7f	113	3	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	113	4	further	further	RB
cord-334123-wb45ww7f	113	5	downstream	downstream	RB
cord-334123-wb45ww7f	113	6	from	from	IN
cord-334123-wb45ww7f	113	7	the	the	DT
cord-334123-wb45ww7f	113	8	3	3	CD
cord-334123-wb45ww7f	113	9	'	'	NN
cord-334123-wb45ww7f	113	10	end	end	NN
cord-334123-wb45ww7f	113	11	of	of	IN
cord-334123-wb45ww7f	113	12	the	the	DT
cord-334123-wb45ww7f	113	13	putative	putative	JJ
cord-334123-wb45ww7f	113	14	stem	stem	NN
cord-334123-wb45ww7f	113	15	is	be	VBZ
cord-334123-wb45ww7f	113	16	a	a	DT
cord-334123-wb45ww7f	113	17	sequence	sequence	NN
cord-334123-wb45ww7f	113	18	of	of	IN
cord-334123-wb45ww7f	113	19	seven	seven	CD
cord-334123-wb45ww7f	113	20	bases	basis	NNS
cord-334123-wb45ww7f	113	21	that	that	WDT
cord-334123-wb45ww7f	113	22	are	be	VBP
cord-334123-wb45ww7f	113	23	complementary	complementary	JJ
cord-334123-wb45ww7f	113	24	to	to	IN
cord-334123-wb45ww7f	113	25	the	the	DT
cord-334123-wb45ww7f	113	26	hairpin	hairpin	JJ
cord-334123-wb45ww7f	113	27	loop	loop	NN
cord-334123-wb45ww7f	113	28	.	.	.
cord-334123-wb45ww7f	114	1	Thus	thus	RB
cord-334123-wb45ww7f	114	2	,	,	,
cord-334123-wb45ww7f	114	3	the	the	DT
cord-334123-wb45ww7f	114	4	overlap	overlap	NN
cord-334123-wb45ww7f	114	5	region	region	NN
cord-334123-wb45ww7f	114	6	encodes	encode	VBZ
cord-334123-wb45ww7f	114	7	a	a	DT
cord-334123-wb45ww7f	114	8	sequence	sequence	NN
cord-334123-wb45ww7f	114	9	that	that	WDT
cord-334123-wb45ww7f	114	10	could	could	MD
cord-334123-wb45ww7f	114	11	fold	fold	VB
cord-334123-wb45ww7f	114	12	into	into	IN
cord-334123-wb45ww7f	114	13	a	a	DT
cord-334123-wb45ww7f	114	14	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	114	15	.	.	.
cord-334123-wb45ww7f	115	1	Support	support	NN
cord-334123-wb45ww7f	115	2	for	for	IN
cord-334123-wb45ww7f	115	3	the	the	DT
cord-334123-wb45ww7f	115	4	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	115	5	structure	structure	NN
cord-334123-wb45ww7f	115	6	was	be	VBD
cord-334123-wb45ww7f	115	7	sought	seek	VBN
cord-334123-wb45ww7f	115	8	by	by	IN
cord-334123-wb45ww7f	115	9	analysis	analysis	NN
cord-334123-wb45ww7f	115	10	of	of	IN
cord-334123-wb45ww7f	115	11	mutants	mutant	NNS
cord-334123-wb45ww7f	115	12	that	that	WDT
cord-334123-wb45ww7f	115	13	alternately	alternately	RB
cord-334123-wb45ww7f	115	14	disrupt	disrupt	VBP
cord-334123-wb45ww7f	115	15	and	and	CC
cord-334123-wb45ww7f	115	16	restore	restore	VB
cord-334123-wb45ww7f	115	17	the	the	DT
cord-334123-wb45ww7f	115	18	proposed	propose	VBN
cord-334123-wb45ww7f	115	19	structure	structure	NN
cord-334123-wb45ww7f	115	20	.	.	.
cord-334123-wb45ww7f	116	1	Mutations	mutation	NNS
cord-334123-wb45ww7f	116	2	that	that	WDT
cord-334123-wb45ww7f	116	3	disrupt	disrupt	VBP
cord-334123-wb45ww7f	116	4	either	either	DT
cord-334123-wb45ww7f	116	5	stem	stem	NN
cord-334123-wb45ww7f	116	6	of	of	IN
cord-334123-wb45ww7f	116	7	the	the	DT
cord-334123-wb45ww7f	116	8	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	116	9	severely	severely	RB
cord-334123-wb45ww7f	116	10	reduce	reduce	VB
cord-334123-wb45ww7f	116	11	frameshifting	frameshifting	NN
cord-334123-wb45ww7f	116	12	,	,	,
cord-334123-wb45ww7f	116	13	while	while	IN
cord-334123-wb45ww7f	116	14	compensatory	compensatory	JJ
cord-334123-wb45ww7f	116	15	mutations	mutation	NNS
cord-334123-wb45ww7f	116	16	that	that	WDT
cord-334123-wb45ww7f	116	17	restore	restore	VBP
cord-334123-wb45ww7f	116	18	the	the	DT
cord-334123-wb45ww7f	116	19	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	116	20	also	also	RB
cord-334123-wb45ww7f	116	21	restore	restore	VB
cord-334123-wb45ww7f	116	22	frameshifting	frameshifting	NN
cord-334123-wb45ww7f	116	23	.	.	.
cord-334123-wb45ww7f	117	1	The	the	DT
cord-334123-wb45ww7f	117	2	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	117	3	inferred	infer	VBN
cord-334123-wb45ww7f	117	4	by	by	IN
cord-334123-wb45ww7f	117	5	this	this	DT
cord-334123-wb45ww7f	117	6	analysis	analysis	NN
cord-334123-wb45ww7f	117	7	is	be	VBZ
cord-334123-wb45ww7f	117	8	a	a	DT
cord-334123-wb45ww7f	117	9	quasicontinuous	quasicontinuous	JJ
cord-334123-wb45ww7f	117	10	helix	helix	NN
cord-334123-wb45ww7f	117	11	of	of	IN
cord-334123-wb45ww7f	117	12	16	16	CD
cord-334123-wb45ww7f	117	13	bp	bp	NNP
cord-334123-wb45ww7f	117	14	,	,	,
cord-334123-wb45ww7f	117	15	and	and	CC
cord-334123-wb45ww7f	117	16	the	the	DT
cord-334123-wb45ww7f	117	17	necessary	necessary	JJ
cord-334123-wb45ww7f	117	18	bridging	bridging	NN
cord-334123-wb45ww7f	117	19	by	by	IN
cord-334123-wb45ww7f	117	20	unpaired	unpaired	JJ
cord-334123-wb45ww7f	117	21	bases	basis	NNS
cord-334123-wb45ww7f	117	22	across	across	IN
cord-334123-wb45ww7f	117	23	the	the	DT
cord-334123-wb45ww7f	117	24	deep	deep	JJ
cord-334123-wb45ww7f	117	25	and	and	CC
cord-334123-wb45ww7f	117	26	shallow	shallow	JJ
cord-334123-wb45ww7f	117	27	grooves	groove	NNS
cord-334123-wb45ww7f	117	28	is	be	VBZ
cord-334123-wb45ww7f	117	29	sterically	sterically	RB
cord-334123-wb45ww7f	117	30	feasible	feasible	JJ
cord-334123-wb45ww7f	117	31	.	.	.
cord-334123-wb45ww7f	118	1	Of	of	IN
cord-334123-wb45ww7f	118	2	the	the	DT
cord-334123-wb45ww7f	118	3	retrovirus	retrovirus	NN
cord-334123-wb45ww7f	118	4	and	and	CC
cord-334123-wb45ww7f	118	5	related	related	JJ
cord-334123-wb45ww7f	118	6	systems	system	NNS
cord-334123-wb45ww7f	118	7	suspected	suspect	VBN
cord-334123-wb45ww7f	118	8	to	to	TO
cord-334123-wb45ww7f	118	9	use	use	VB
cord-334123-wb45ww7f	118	10	-1	-1	NNP
cord-334123-wb45ww7f	118	11	frameshifting	frameshifting	NN
cord-334123-wb45ww7f	118	12	,	,	,
cord-334123-wb45ww7f	118	13	Brierley	Brierley	NNP
cord-334123-wb45ww7f	118	14	et	et	NNP
cord-334123-wb45ww7f	118	15	al	al	NNP
cord-334123-wb45ww7f	118	16	.	.	.
cord-334123-wb45ww7f	119	1	(	(	-LRB-
cord-334123-wb45ww7f	119	2	1989	1989	CD
cord-334123-wb45ww7f	119	3	)	)	-RRB-
cord-334123-wb45ww7f	119	4	found	find	VBD
cord-334123-wb45ww7f	119	5	that	that	IN
cord-334123-wb45ww7f	119	6	over	over	IN
cord-334123-wb45ww7f	119	7	half	half	NN
cord-334123-wb45ww7f	119	8	have	have	VBP
cord-334123-wb45ww7f	119	9	the	the	DT
cord-334123-wb45ww7f	119	10	potential	potential	NN
cord-334123-wb45ww7f	119	11	for	for	IN
cord-334123-wb45ww7f	119	12	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	119	13	formation	formation	NN
cord-334123-wb45ww7f	119	14	immediately	immediately	RB
cord-334123-wb45ww7f	119	15	downstream	downstream	RB
cord-334123-wb45ww7f	119	16	of	of	IN
cord-334123-wb45ww7f	119	17	the	the	DT
cord-334123-wb45ww7f	119	18	lo	lo	NNP
cord-334123-wb45ww7f	119	19	-	-	HYPH
cord-334123-wb45ww7f	119	20	cation	cation	NNP
cord-334123-wb45ww7f	119	21	of	of	IN
cord-334123-wb45ww7f	119	22	the	the	DT
cord-334123-wb45ww7f	119	23	frameshift	frameshift	NN
cord-334123-wb45ww7f	119	24	.	.	.
cord-334123-wb45ww7f	120	1	This	this	DT
cord-334123-wb45ww7f	120	2	includes	include	VBZ
cord-334123-wb45ww7f	120	3	three	three	CD
cord-334123-wb45ww7f	120	4	of	of	IN
cord-334123-wb45ww7f	120	5	the	the	DT
cord-334123-wb45ww7f	120	6	four	four	CD
cord-334123-wb45ww7f	120	7	systems	system	NNS
cord-334123-wb45ww7f	120	8	where	where	WRB
cord-334123-wb45ww7f	120	9	frameshifting	frameshifting	NNP
cord-334123-wb45ww7f	120	10	has	have	VBZ
cord-334123-wb45ww7f	120	11	actually	actually	RB
cord-334123-wb45ww7f	120	12	been	be	VBN
cord-334123-wb45ww7f	120	13	confirmed	confirm	VBN
cord-334123-wb45ww7f	120	14	.	.	.
cord-334123-wb45ww7f	121	1	It	-PRON-	PRP
cord-334123-wb45ww7f	121	2	is	be	VBZ
cord-334123-wb45ww7f	121	3	perhaps	perhaps	RB
cord-334123-wb45ww7f	121	4	significant	significant	JJ
cord-334123-wb45ww7f	121	5	that	that	IN
cord-334123-wb45ww7f	121	6	Jacks	Jacks	NNP
cord-334123-wb45ww7f	121	7	et	et	NNP
cord-334123-wb45ww7f	121	8	al	al	NNP
cord-334123-wb45ww7f	121	9	.	.	.
cord-334123-wb45ww7f	122	1	(	(	-LRB-
cord-334123-wb45ww7f	122	2	1988	1988	CD
cord-334123-wb45ww7f	122	3	)	)	-RRB-
cord-334123-wb45ww7f	122	4	had	have	VBD
cord-334123-wb45ww7f	122	5	shown	show	VBN
cord-334123-wb45ww7f	122	6	that	that	IN
cord-334123-wb45ww7f	122	7	frameshifting	frameshifting	NN
cord-334123-wb45ww7f	122	8	is	be	VBZ
cord-334123-wb45ww7f	122	9	attenuated	attenuate	VBN
cord-334123-wb45ww7f	122	10	upon	upon	IN
cord-334123-wb45ww7f	122	11	deletion	deletion	NN
cord-334123-wb45ww7f	122	12	of	of	IN
cord-334123-wb45ww7f	122	13	a	a	DT
cord-334123-wb45ww7f	122	14	region	region	NN
cord-334123-wb45ww7f	122	15	downstream	downstream	RB
cord-334123-wb45ww7f	122	16	of	of	IN
cord-334123-wb45ww7f	122	17	the	the	DT
cord-334123-wb45ww7f	122	18	critical	critical	JJ
cord-334123-wb45ww7f	122	19	stem	stem	NN
cord-334123-wb45ww7f	122	20	in	in	IN
cord-334123-wb45ww7f	122	21	Rous	rous	JJ
cord-334123-wb45ww7f	122	22	sarcoma	sarcoma	NN
cord-334123-wb45ww7f	122	23	virus	virus	NN
cord-334123-wb45ww7f	122	24	mRNA	mrna	NN
cord-334123-wb45ww7f	122	25	.	.	.
cord-334123-wb45ww7f	123	1	The	the	DT
cord-334123-wb45ww7f	123	2	mechanism	mechanism	NN
cord-334123-wb45ww7f	123	3	for	for	IN
cord-334123-wb45ww7f	123	4	the	the	DT
cord-334123-wb45ww7f	123	5	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	123	6	-	-	HYPH
cord-334123-wb45ww7f	123	7	induced	induce	VBN
cord-334123-wb45ww7f	123	8	frameshift	frameshift	NN
cord-334123-wb45ww7f	123	9	is	be	VBZ
cord-334123-wb45ww7f	123	10	unknown	unknown	JJ
cord-334123-wb45ww7f	123	11	but	but	CC
cord-334123-wb45ww7f	123	12	there	there	EX
cord-334123-wb45ww7f	123	13	are	be	VBP
cord-334123-wb45ww7f	123	14	several	several	JJ
cord-334123-wb45ww7f	123	15	points	point	NNS
cord-334123-wb45ww7f	123	16	worth	worth	JJ
cord-334123-wb45ww7f	123	17	noting	note	VBG
cord-334123-wb45ww7f	123	18	.	.	.
cord-334123-wb45ww7f	124	1	Mechanisms	mechanism	NNS
cord-334123-wb45ww7f	124	2	for	for	IN
cord-334123-wb45ww7f	124	3	frameshifting	frameshifte	VBG
cord-334123-wb45ww7f	124	4	with	with	IN
cord-334123-wb45ww7f	124	5	natural	natural	JJ
cord-334123-wb45ww7f	124	6	as	as	IN
cord-334123-wb45ww7f	124	7	opposed	oppose	VBN
cord-334123-wb45ww7f	124	8	to	to	IN
cord-334123-wb45ww7f	124	9	mutant	mutant	JJ
cord-334123-wb45ww7f	124	10	tRNAs	trna	NNS
cord-334123-wb45ww7f	124	11	have	have	VBP
cord-334123-wb45ww7f	124	12	been	be	VBN
cord-334123-wb45ww7f	124	13	studied	study	VBN
cord-334123-wb45ww7f	124	14	in	in	IN
cord-334123-wb45ww7f	124	15	bacteria	bacteria	NNS
cord-334123-wb45ww7f	124	16	and	and	CC
cord-334123-wb45ww7f	124	17	eukaryotes	eukaryote	NNS
cord-334123-wb45ww7f	124	18	(	(	-LRB-
cord-334123-wb45ww7f	124	19	reviewed	review	VBN
cord-334123-wb45ww7f	124	20	in	in	IN
cord-334123-wb45ww7f	124	21	Roth	Roth	NNP
cord-334123-wb45ww7f	124	22	,	,	,
cord-334123-wb45ww7f	124	23	1981	1981	CD
cord-334123-wb45ww7f	124	24	;	;	:
cord-334123-wb45ww7f	124	25	Craigen	Craigen	NNP
cord-334123-wb45ww7f	124	26	and	and	CC
cord-334123-wb45ww7f	124	27	Caskey	Caskey	NNP
cord-334123-wb45ww7f	124	28	,	,	,
cord-334123-wb45ww7f	124	29	1987	1987	CD
cord-334123-wb45ww7f	124	30	)	)	-RRB-
cord-334123-wb45ww7f	124	31	.	.	.
cord-334123-wb45ww7f	125	1	In	in	IN
cord-334123-wb45ww7f	125	2	bacteria	bacteria	NNS
cord-334123-wb45ww7f	125	3	,	,	,
cord-334123-wb45ww7f	125	4	frameshift	frameshift	NN
cord-334123-wb45ww7f	125	5	suppression	suppression	NN
cord-334123-wb45ww7f	125	6	can	can	MD
cord-334123-wb45ww7f	125	7	occur	occur	VB
cord-334123-wb45ww7f	125	8	as	as	IN
cord-334123-wb45ww7f	125	9	a	a	DT
cord-334123-wb45ww7f	125	10	result	result	NN
cord-334123-wb45ww7f	125	11	of	of	IN
cord-334123-wb45ww7f	125	12	translational	translational	JJ
cord-334123-wb45ww7f	125	13	pausing	pausing	NN
cord-334123-wb45ww7f	125	14	,	,	,
cord-334123-wb45ww7f	125	15	which	which	WDT
cord-334123-wb45ww7f	125	16	is	be	VBZ
cord-334123-wb45ww7f	125	17	caused	cause	VBN
cord-334123-wb45ww7f	125	18	,	,	,
cord-334123-wb45ww7f	125	19	for	for	IN
cord-334123-wb45ww7f	125	20	example	example	NN
cord-334123-wb45ww7f	125	21	,	,	,
cord-334123-wb45ww7f	125	22	by	by	IN
cord-334123-wb45ww7f	125	23	starvation	starvation	NN
cord-334123-wb45ww7f	125	24	for	for	IN
cord-334123-wb45ww7f	125	25	an	an	DT
cord-334123-wb45ww7f	125	26	amino	amino	NN
cord-334123-wb45ww7f	125	27	acid	acid	NN
cord-334123-wb45ww7f	125	28	.	.	.
cord-334123-wb45ww7f	126	1	In	in	IN
cord-334123-wb45ww7f	126	2	this	this	DT
cord-334123-wb45ww7f	126	3	case	case	NN
cord-334123-wb45ww7f	126	4	,	,	,
cord-334123-wb45ww7f	126	5	frameshifting	frameshifte	VBG
cord-334123-wb45ww7f	126	6	results	result	NNS
cord-334123-wb45ww7f	126	7	from	from	IN
cord-334123-wb45ww7f	126	8	the	the	DT
cord-334123-wb45ww7f	126	9	use	use	NN
cord-334123-wb45ww7f	126	10	of	of	IN
cord-334123-wb45ww7f	126	11	a	a	DT
cord-334123-wb45ww7f	126	12	surrogate	surrogate	NN
cord-334123-wb45ww7f	126	13	charged	charge	VBN
cord-334123-wb45ww7f	126	14	tRNA	trna	NN
cord-334123-wb45ww7f	126	15	in	in	IN
cord-334123-wb45ww7f	126	16	place	place	NN
cord-334123-wb45ww7f	126	17	of	of	IN
cord-334123-wb45ww7f	126	18	the	the	DT
cord-334123-wb45ww7f	126	19	correct	correct	JJ
cord-334123-wb45ww7f	126	20	charged	charge	VBN
cord-334123-wb45ww7f	126	21	species	specie	NNS
cord-334123-wb45ww7f	126	22	(	(	-LRB-
cord-334123-wb45ww7f	126	23	which	which	WDT
cord-334123-wb45ww7f	126	24	is	be	VBZ
cord-334123-wb45ww7f	126	25	in	in	IN
cord-334123-wb45ww7f	126	26	limiting	limit	VBG
cord-334123-wb45ww7f	126	27	amounts	amount	NNS
cord-334123-wb45ww7f	126	28	)	)	-RRB-
cord-334123-wb45ww7f	126	29	.	.	.
cord-334123-wb45ww7f	127	1	Thus	thus	RB
cord-334123-wb45ww7f	127	2	,	,	,
cord-334123-wb45ww7f	127	3	a	a	DT
cord-334123-wb45ww7f	127	4	transiently	transiently	RB
cord-334123-wb45ww7f	127	5	unoccupied	unoccupied	JJ
cord-334123-wb45ww7f	127	6	A	a	NN
cord-334123-wb45ww7f	127	7	-	-	HYPH
cord-334123-wb45ww7f	127	8	site	site	NN
cord-334123-wb45ww7f	127	9	on	on	IN
cord-334123-wb45ww7f	127	10	the	the	DT
cord-334123-wb45ww7f	127	11	ribosome	ribosome	NN
cord-334123-wb45ww7f	127	12	may	may	MD
cord-334123-wb45ww7f	127	13	be	be	VB
cord-334123-wb45ww7f	127	14	"	"	``
cord-334123-wb45ww7f	127	15	read	read	VBN
cord-334123-wb45ww7f	127	16	"	"	''
cord-334123-wb45ww7f	127	17	by	by	IN
cord-334123-wb45ww7f	127	18	a	a	DT
cord-334123-wb45ww7f	127	19	noncognate	noncognate	NNP
cord-334123-wb45ww7f	127	20	tRNA	tRNA	NNP
cord-334123-wb45ww7f	127	21	and	and	CC
cord-334123-wb45ww7f	127	22	that	that	DT
cord-334123-wb45ww7f	127	23	event	event	NN
cord-334123-wb45ww7f	127	24	can	can	MD
cord-334123-wb45ww7f	127	25	be	be	VB
cord-334123-wb45ww7f	127	26	accompanied	accompany	VBN
cord-334123-wb45ww7f	127	27	by	by	IN
cord-334123-wb45ww7f	127	28	a	a	DT
cord-334123-wb45ww7f	127	29	frameshift	frameshift	NN
cord-334123-wb45ww7f	127	30	and	and	CC
cord-334123-wb45ww7f	127	31	a	a	DT
cord-334123-wb45ww7f	127	32	missense	missense	JJ
cord-334123-wb45ww7f	127	33	substitution	substitution	NN
cord-334123-wb45ww7f	127	34	.	.	.
cord-334123-wb45ww7f	128	1	The	the	DT
cord-334123-wb45ww7f	128	2	frameshifts	frameshift	NNS
cord-334123-wb45ww7f	128	3	that	that	WDT
cord-334123-wb45ww7f	128	4	lead	lead	VBP
cord-334123-wb45ww7f	128	5	to	to	IN
cord-334123-wb45ww7f	128	6	fusion	fusion	NN
cord-334123-wb45ww7f	128	7	proteins	protein	NNS
cord-334123-wb45ww7f	128	8	in	in	IN
cord-334123-wb45ww7f	128	9	the	the	DT
cord-334123-wb45ww7f	128	10	retroviral	retroviral	NN
cord-334123-wb45ww7f	128	11	and	and	CC
cord-334123-wb45ww7f	128	12	IBV	IBV	NNP
cord-334123-wb45ww7f	128	13	examples	example	NNS
cord-334123-wb45ww7f	128	14	are	be	VBP
cord-334123-wb45ww7f	128	15	different	different	JJ
cord-334123-wb45ww7f	128	16	in	in	IN
cord-334123-wb45ww7f	128	17	that	that	IN
cord-334123-wb45ww7f	128	18	the	the	DT
cord-334123-wb45ww7f	128	19	double	double	JJ
cord-334123-wb45ww7f	128	20	frameshift	frameshift	NN
cord-334123-wb45ww7f	128	21	event	event	NN
cord-334123-wb45ww7f	128	22	is	be	VBZ
cord-334123-wb45ww7f	128	23	not	not	RB
cord-334123-wb45ww7f	128	24	accompanied	accompany	VBN
cord-334123-wb45ww7f	128	25	by	by	IN
cord-334123-wb45ww7f	128	26	missense	missense	NN
cord-334123-wb45ww7f	128	27	substitutions	substitution	NNS
cord-334123-wb45ww7f	128	28	.	.	.
cord-334123-wb45ww7f	129	1	This	this	DT
cord-334123-wb45ww7f	129	2	suggests	suggest	VBZ
cord-334123-wb45ww7f	129	3	that	that	IN
cord-334123-wb45ww7f	129	4	a	a	DT
cord-334123-wb45ww7f	129	5	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	129	6	does	do	VBZ
cord-334123-wb45ww7f	129	7	not	not	RB
cord-334123-wb45ww7f	129	8	simply	simply	RB
cord-334123-wb45ww7f	129	9	produce	produce	VB
cord-334123-wb45ww7f	129	10	an	an	DT
cord-334123-wb45ww7f	129	11	unoccupied	unoccupied	JJ
cord-334123-wb45ww7f	129	12	A	a	NN
cord-334123-wb45ww7f	129	13	-	-	HYPH
cord-334123-wb45ww7f	129	14	site	site	NN
cord-334123-wb45ww7f	129	15	.	.	.
cord-334123-wb45ww7f	130	1	It	-PRON-	PRP
cord-334123-wb45ww7f	130	2	is	be	VBZ
cord-334123-wb45ww7f	130	3	not	not	RB
cord-334123-wb45ww7f	130	4	known	know	VBN
cord-334123-wb45ww7f	130	5	whether	whether	IN
cord-334123-wb45ww7f	130	6	a	a	DT
cord-334123-wb45ww7f	130	7	single	single	JJ
cord-334123-wb45ww7f	130	8	hairpin	hairpin	NN
cord-334123-wb45ww7f	130	9	stem	stem	NN
cord-334123-wb45ww7f	130	10	equal	equal	JJ
cord-334123-wb45ww7f	130	11	in	in	IN
cord-334123-wb45ww7f	130	12	length	length	NN
cord-334123-wb45ww7f	130	13	to	to	IN
cord-334123-wb45ww7f	130	14	the	the	DT
cord-334123-wb45ww7f	130	15	elongated	elongated	JJ
cord-334123-wb45ww7f	130	16	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	130	17	structure	structure	NN
cord-334123-wb45ww7f	130	18	would	would	MD
cord-334123-wb45ww7f	130	19	be	be	VB
cord-334123-wb45ww7f	130	20	as	as	RB
cord-334123-wb45ww7f	130	21	effective	effective	JJ
cord-334123-wb45ww7f	130	22	in	in	IN
cord-334123-wb45ww7f	130	23	inducing	induce	VBG
cord-334123-wb45ww7f	130	24	a	a	DT
cord-334123-wb45ww7f	130	25	frameshift	frameshift	NN
cord-334123-wb45ww7f	130	26	in	in	IN
cord-334123-wb45ww7f	130	27	the	the	DT
cord-334123-wb45ww7f	130	28	system	system	NN
cord-334123-wb45ww7f	130	29	studied	study	VBN
cord-334123-wb45ww7f	130	30	by	by	IN
cord-334123-wb45ww7f	130	31	Brierley	Brierley	NNP
cord-334123-wb45ww7f	130	32	et	et	NNP
cord-334123-wb45ww7f	130	33	al	al	NNP
cord-334123-wb45ww7f	130	34	.	.	.
cord-334123-wb45ww7f	131	1	(	(	-LRB-
cord-334123-wb45ww7f	131	2	1989	1989	CD
cord-334123-wb45ww7f	131	3	)	)	-RRB-
cord-334123-wb45ww7f	131	4	.	.	.
cord-334123-wb45ww7f	132	1	The	the	DT
cord-334123-wb45ww7f	132	2	authors	author	NNS
cord-334123-wb45ww7f	132	3	show	show	VBP
cord-334123-wb45ww7f	132	4	that	that	IN
cord-334123-wb45ww7f	132	5	the	the	DT
cord-334123-wb45ww7f	132	6	upstream	upstream	JJ
cord-334123-wb45ww7f	132	7	stem	stem	NN
cord-334123-wb45ww7f	132	8	alone	alone	RB
cord-334123-wb45ww7f	132	9	induces	induce	VBZ
cord-334123-wb45ww7f	132	10	frameshifting	frameshifte	VBG
cord-334123-wb45ww7f	132	11	,	,	,
cord-334123-wb45ww7f	132	12	but	but	CC
cord-334123-wb45ww7f	132	13	at	at	IN
cord-334123-wb45ww7f	132	14	a	a	DT
cord-334123-wb45ww7f	132	15	much	much	RB
cord-334123-wb45ww7f	132	16	lower	low	JJR
cord-334123-wb45ww7f	132	17	efficiency	efficiency	NN
cord-334123-wb45ww7f	132	18	than	than	IN
cord-334123-wb45ww7f	132	19	when	when	WRB
cord-334123-wb45ww7f	132	20	the	the	DT
cord-334123-wb45ww7f	132	21	downstream	downstream	JJ
cord-334123-wb45ww7f	132	22	sequences	sequence	NNS
cord-334123-wb45ww7f	132	23	are	be	VBP
cord-334123-wb45ww7f	132	24	allowed	allow	VBN
cord-334123-wb45ww7f	132	25	to	to	TO
cord-334123-wb45ww7f	132	26	form	form	VB
cord-334123-wb45ww7f	132	27	the	the	DT
cord-334123-wb45ww7f	132	28	second	second	JJ
cord-334123-wb45ww7f	132	29	stem	stem	NN
cord-334123-wb45ww7f	132	30	that	that	WDT
cord-334123-wb45ww7f	132	31	results	result	VBZ
cord-334123-wb45ww7f	132	32	in	in	IN
cord-334123-wb45ww7f	132	33	a	a	DT
cord-334123-wb45ww7f	132	34	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	132	35	minihelix	minihelix	NNP
cord-334123-wb45ww7f	132	36	.	.	.
cord-334123-wb45ww7f	133	1	Thus	thus	RB
cord-334123-wb45ww7f	133	2	,	,	,
cord-334123-wb45ww7f	133	3	the	the	DT
cord-334123-wb45ww7f	133	4	frequency	frequency	NN
cord-334123-wb45ww7f	133	5	of	of	IN
cord-334123-wb45ww7f	133	6	frameshifting	frameshifte	VBG
cord-334123-wb45ww7f	133	7	may	may	NN
cord-334123-wb45ww7f	133	8	in	in	IN
cord-334123-wb45ww7f	133	9	principal	principal	NN
cord-334123-wb45ww7f	133	10	be	be	VB
cord-334123-wb45ww7f	133	11	fine	fine	RB
cord-334123-wb45ww7f	133	12	-	-	HYPH
cord-334123-wb45ww7f	133	13	tuned	tune	VBN
cord-334123-wb45ww7f	133	14	by	by	IN
cord-334123-wb45ww7f	133	15	the	the	DT
cord-334123-wb45ww7f	133	16	size	size	NN
cord-334123-wb45ww7f	133	17	and	and	CC
cord-334123-wb45ww7f	133	18	detailed	detailed	JJ
cord-334123-wb45ww7f	133	19	structure	structure	NN
cord-334123-wb45ww7f	133	20	of	of	IN
cord-334123-wb45ww7f	133	21	the	the	DT
cord-334123-wb45ww7f	133	22	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	133	23	.	.	.
cord-334123-wb45ww7f	134	1	I	-PRON-	PRP
cord-334123-wb45ww7f	134	2	can	can	MD
cord-334123-wb45ww7f	134	3	suggest	suggest	VB
cord-334123-wb45ww7f	134	4	one	one	CD
cord-334123-wb45ww7f	134	5	possible	possible	JJ
cord-334123-wb45ww7f	134	6	advantage	advantage	NN
cord-334123-wb45ww7f	134	7	to	to	IN
cord-334123-wb45ww7f	134	8	the	the	DT
cord-334123-wb45ww7f	134	9	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	134	10	format	format	NN
cord-334123-wb45ww7f	134	11	over	over	IN
cord-334123-wb45ww7f	134	12	a	a	DT
cord-334123-wb45ww7f	134	13	standard	standard	JJ
cord-334123-wb45ww7f	134	14	hairpin	hairpin	NN
cord-334123-wb45ww7f	134	15	helix	helix	NN
cord-334123-wb45ww7f	134	16	of	of	IN
cord-334123-wb45ww7f	134	17	equivalent	equivalent	JJ
cord-334123-wb45ww7f	134	18	size	size	NN
cord-334123-wb45ww7f	134	19	.	.	.
cord-334123-wb45ww7f	135	1	In	in	IN
cord-334123-wb45ww7f	135	2	the	the	DT
cord-334123-wb45ww7f	135	3	work	work	NN
cord-334123-wb45ww7f	135	4	of	of	IN
cord-334123-wb45ww7f	135	5	Puglisi	Puglisi	NNP
cord-334123-wb45ww7f	135	6	et	et	NNP
cord-334123-wb45ww7f	135	7	al	al	NNP
cord-334123-wb45ww7f	135	8	.	.	.
cord-334123-wb45ww7f	136	1	(	(	-LRB-
cord-334123-wb45ww7f	136	2	1988	1988	CD
cord-334123-wb45ww7f	136	3	)	)	-RRB-
cord-334123-wb45ww7f	136	4	the	the	DT
cord-334123-wb45ww7f	136	5	thermal	thermal	JJ
cord-334123-wb45ww7f	136	6	stability	stability	NN
cord-334123-wb45ww7f	136	7	of	of	IN
cord-334123-wb45ww7f	136	8	the	the	DT
cord-334123-wb45ww7f	136	9	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	136	10	helix	helix	NNP
cord-334123-wb45ww7f	136	11	was	be	VBD
cord-334123-wb45ww7f	136	12	not	not	RB
cord-334123-wb45ww7f	136	13	greater	great	JJR
cord-334123-wb45ww7f	136	14	than	than	IN
cord-334123-wb45ww7f	136	15	that	that	DT
cord-334123-wb45ww7f	136	16	of	of	IN
cord-334123-wb45ww7f	136	17	the	the	DT
cord-334123-wb45ww7f	136	18	moststable	moststable	NN
cord-334123-wb45ww7f	136	19	of	of	IN
cord-334123-wb45ww7f	136	20	the	the	DT
cord-334123-wb45ww7f	136	21	two	two	CD
cord-334123-wb45ww7f	136	22	stems	stem	NNS
cord-334123-wb45ww7f	136	23	from	from	IN
cord-334123-wb45ww7f	136	24	which	which	WDT
cord-334123-wb45ww7f	136	25	it	-PRON-	PRP
cord-334123-wb45ww7f	136	26	was	be	VBD
cord-334123-wb45ww7f	136	27	assembled	assemble	VBN
cord-334123-wb45ww7f	136	28	.	.	.
cord-334123-wb45ww7f	137	1	If	if	IN
cord-334123-wb45ww7f	137	2	this	this	DT
cord-334123-wb45ww7f	137	3	is	be	VBZ
cord-334123-wb45ww7f	137	4	a	a	DT
cord-334123-wb45ww7f	137	5	general	general	JJ
cord-334123-wb45ww7f	137	6	principle	principle	NN
cord-334123-wb45ww7f	137	7	,	,	,
cord-334123-wb45ww7f	137	8	then	then	RB
cord-334123-wb45ww7f	137	9	pseudoknots	pseudoknot	NNS
cord-334123-wb45ww7f	137	10	provide	provide	VBP
cord-334123-wb45ww7f	137	11	a	a	DT
cord-334123-wb45ww7f	137	12	way	way	NN
cord-334123-wb45ww7f	137	13	to	to	TO
cord-334123-wb45ww7f	137	14	generate	generate	VB
cord-334123-wb45ww7f	137	15	minihelices	minihelice	NNS
cord-334123-wb45ww7f	137	16	that	that	WDT
cord-334123-wb45ww7f	137	17	have	have	VBP
cord-334123-wb45ww7f	137	18	lower	low	JJR
cord-334123-wb45ww7f	137	19	stabilities	stability	NNS
cord-334123-wb45ww7f	137	20	than	than	IN
cord-334123-wb45ww7f	137	21	their	-PRON-	PRP$
cord-334123-wb45ww7f	137	22	counterparts	counterpart	NNS
cord-334123-wb45ww7f	137	23	,	,	,
cord-334123-wb45ww7f	137	24	which	which	WDT
cord-334123-wb45ww7f	137	25	are	be	VBP
cord-334123-wb45ww7f	137	26	assembled	assemble	VBN
cord-334123-wb45ww7f	137	27	as	as	IN
cord-334123-wb45ww7f	137	28	unknotted	unknotted	JJ
cord-334123-wb45ww7f	137	29	continuous	continuous	JJ
cord-334123-wb45ww7f	137	30	hairpins	hairpin	NNS
cord-334123-wb45ww7f	137	31	with	with	IN
cord-334123-wb45ww7f	137	32	the	the	DT
cord-334123-wb45ww7f	137	33	same	same	JJ
cord-334123-wb45ww7f	137	34	number	number	NN
cord-334123-wb45ww7f	137	35	of	of	IN
cord-334123-wb45ww7f	137	36	base	base	NN
cord-334123-wb45ww7f	137	37	pairs	pair	NNS
cord-334123-wb45ww7f	137	38	.	.	.
cord-334123-wb45ww7f	138	1	The	the	DT
cord-334123-wb45ww7f	138	2	reduction	reduction	NN
cord-334123-wb45ww7f	138	3	in	in	IN
cord-334123-wb45ww7f	138	4	stability	stability	NN
cord-334123-wb45ww7f	138	5	may	may	MD
cord-334123-wb45ww7f	138	6	be	be	VB
cord-334123-wb45ww7f	138	7	critical	critical	JJ
cord-334123-wb45ww7f	138	8	for	for	IN
cord-334123-wb45ww7f	138	9	efficient	efficient	JJ
cord-334123-wb45ww7f	138	10	movement	movement	NN
cord-334123-wb45ww7f	138	11	of	of	IN
cord-334123-wb45ww7f	138	12	ribosomes	ribosome	NNS
cord-334123-wb45ww7f	138	13	through	through	IN
cord-334123-wb45ww7f	138	14	an	an	DT
cord-334123-wb45ww7f	138	15	element	element	NN
cord-334123-wb45ww7f	138	16	of	of	IN
cord-334123-wb45ww7f	138	17	secondary	secondary	JJ
cord-334123-wb45ww7f	138	18	structure	structure	NN
cord-334123-wb45ww7f	138	19	in	in	IN
cord-334123-wb45ww7f	138	20	an	an	DT
cord-334123-wb45ww7f	138	21	mRNA	mrna	NN
cord-334123-wb45ww7f	138	22	.	.	.
cord-334123-wb45ww7f	139	1	Even	even	RB
cord-334123-wb45ww7f	139	2	the	the	DT
cord-334123-wb45ww7f	139	3	spatial	spatial	JJ
cord-334123-wb45ww7f	139	4	location	location	NN
cord-334123-wb45ww7f	139	5	of	of	IN
cord-334123-wb45ww7f	139	6	the	the	DT
cord-334123-wb45ww7f	139	7	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	139	8	relative	relative	JJ
cord-334123-wb45ww7f	139	9	to	to	IN
cord-334123-wb45ww7f	139	10	the	the	DT
cord-334123-wb45ww7f	139	11	frameshift	frameshift	NN
cord-334123-wb45ww7f	139	12	site	site	NN
cord-334123-wb45ww7f	139	13	in	in	IN
cord-334123-wb45ww7f	139	14	IBV	IBV	NNP
cord-334123-wb45ww7f	139	15	RNA	RNA	NNP
cord-334123-wb45ww7f	139	16	is	be	VBZ
cord-334123-wb45ww7f	139	17	sharply	sharply	RB
cord-334123-wb45ww7f	139	18	constrained	constrain	VBN
cord-334123-wb45ww7f	139	19	-	-	:
cord-334123-wb45ww7f	139	20	to	to	TO
cord-334123-wb45ww7f	139	21	less	less	JJR
cord-334123-wb45ww7f	139	22	than	than	IN
cord-334123-wb45ww7f	139	23	three	three	CD
cord-334123-wb45ww7f	139	24	nucleotides	nucleotide	NNS
cord-334123-wb45ww7f	139	25	(	(	-LRB-
cord-334123-wb45ww7f	139	26	Brierley	Brierley	NNP
cord-334123-wb45ww7f	139	27	et	et	NNP
cord-334123-wb45ww7f	139	28	al	al	NNP
cord-334123-wb45ww7f	139	29	.	.	NNP
cord-334123-wb45ww7f	139	30	,	,	,
cord-334123-wb45ww7f	139	31	1989	1989	CD
cord-334123-wb45ww7f	139	32	)	)	-RRB-
cord-334123-wb45ww7f	139	33	.	.	.
cord-334123-wb45ww7f	140	1	This	this	DT
cord-334123-wb45ww7f	140	2	emphasizes	emphasize	VBZ
cord-334123-wb45ww7f	140	3	the	the	DT
cord-334123-wb45ww7f	140	4	importance	importance	NN
cord-334123-wb45ww7f	140	5	of	of	IN
cord-334123-wb45ww7f	140	6	structural	structural	JJ
cord-334123-wb45ww7f	140	7	detail	detail	NN
cord-334123-wb45ww7f	140	8	and	and	CC
cord-334123-wb45ww7f	140	9	context	context	NN
cord-334123-wb45ww7f	140	10	for	for	IN
cord-334123-wb45ww7f	140	11	the	the	DT
cord-334123-wb45ww7f	140	12	biological	biological	JJ
cord-334123-wb45ww7f	140	13	function	function	NN
cord-334123-wb45ww7f	140	14	of	of	IN
cord-334123-wb45ww7f	140	15	the	the	DT
cord-334123-wb45ww7f	140	16	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	140	17	in	in	IN
cord-334123-wb45ww7f	140	18	translation	translation	NN
cord-334123-wb45ww7f	140	19	.	.	.
cord-334123-wb45ww7f	141	1	In	in	IN
cord-334123-wb45ww7f	141	2	this	this	DT
cord-334123-wb45ww7f	141	3	and	and	CC
cord-334123-wb45ww7f	141	4	other	other	JJ
cord-334123-wb45ww7f	141	5	respects	respect	NNS
cord-334123-wb45ww7f	141	6	,	,	,
cord-334123-wb45ww7f	141	7	it	-PRON-	PRP
cord-334123-wb45ww7f	141	8	has	have	VBZ
cord-334123-wb45ww7f	141	9	the	the	DT
cord-334123-wb45ww7f	141	10	properties	property	NNS
cord-334123-wb45ww7f	141	11	of	of	IN
cord-334123-wb45ww7f	141	12	a	a	DT
cord-334123-wb45ww7f	141	13	substrate	substrate	NN
cord-334123-wb45ww7f	141	14	that	that	WDT
cord-334123-wb45ww7f	141	15	is	be	VBZ
cord-334123-wb45ww7f	141	16	specifically	specifically	RB
cord-334123-wb45ww7f	141	17	recognized	recognize	VBN
cord-334123-wb45ww7f	141	18	and	and	CC
cord-334123-wb45ww7f	141	19	acted	act	VBN
cord-334123-wb45ww7f	141	20	upon	upon	IN
cord-334123-wb45ww7f	141	21	by	by	IN
cord-334123-wb45ww7f	141	22	an	an	DT
cord-334123-wb45ww7f	141	23	enzyme	enzyme	NN
cord-334123-wb45ww7f	141	24	sensitive	sensitive	JJ
cord-334123-wb45ww7f	141	25	to	to	IN
cord-334123-wb45ww7f	141	26	details	detail	NNS
cord-334123-wb45ww7f	141	27	of	of	IN
cord-334123-wb45ww7f	141	28	molecular	molecular	JJ
cord-334123-wb45ww7f	141	29	shape	shape	NN
cord-334123-wb45ww7f	141	30	and	and	CC
cord-334123-wb45ww7f	141	31	the	the	DT
cord-334123-wb45ww7f	141	32	spacing	spacing	NN
cord-334123-wb45ww7f	141	33	of	of	IN
cord-334123-wb45ww7f	141	34	functional	functional	JJ
cord-334123-wb45ww7f	141	35	groups	group	NNS
cord-334123-wb45ww7f	141	36	.	.	.
cord-334123-wb45ww7f	142	1	There	there	EX
cord-334123-wb45ww7f	142	2	is	be	VBZ
cord-334123-wb45ww7f	142	3	no	no	DT
cord-334123-wb45ww7f	142	4	evidence	evidence	NN
cord-334123-wb45ww7f	142	5	that	that	IN
cord-334123-wb45ww7f	142	6	a	a	DT
cord-334123-wb45ww7f	142	7	component	component	NN
cord-334123-wb45ww7f	142	8	of	of	IN
cord-334123-wb45ww7f	142	9	the	the	DT
cord-334123-wb45ww7f	142	10	translation	translation	NN
cord-334123-wb45ww7f	142	11	apparatus	apparatus	NN
cord-334123-wb45ww7f	142	12	(	(	-LRB-
cord-334123-wb45ww7f	142	13	e.g.	e.g.	RB
cord-334123-wb45ww7f	142	14	,	,	,
cord-334123-wb45ww7f	142	15	ribosomes	ribosome	NNS
cord-334123-wb45ww7f	142	16	)	)	-RRB-
cord-334123-wb45ww7f	142	17	performs	perform	VBZ
cord-334123-wb45ww7f	142	18	such	such	PDT
cord-334123-wb45ww7f	142	19	a	a	DT
cord-334123-wb45ww7f	142	20	recognition	recognition	NN
cord-334123-wb45ww7f	142	21	function	function	NN
cord-334123-wb45ww7f	142	22	before	before	IN
cord-334123-wb45ww7f	142	23	triggering	trigger	VBG
cord-334123-wb45ww7f	142	24	the	the	DT
cord-334123-wb45ww7f	142	25	double	double	JJ
cord-334123-wb45ww7f	142	26	frameshift	frameshift	NN
cord-334123-wb45ww7f	142	27	,	,	,
cord-334123-wb45ww7f	142	28	but	but	CC
cord-334123-wb45ww7f	142	29	operationally	operationally	RB
cord-334123-wb45ww7f	142	30	the	the	DT
cord-334123-wb45ww7f	142	31	result	result	NN
cord-334123-wb45ww7f	142	32	is	be	VBZ
cord-334123-wb45ww7f	142	33	the	the	DT
cord-334123-wb45ww7f	142	34	same	same	JJ
cord-334123-wb45ww7f	142	35	and	and	CC
cord-334123-wb45ww7f	142	36	the	the	DT
cord-334123-wb45ww7f	142	37	possibility	possibility	NN
cord-334123-wb45ww7f	142	38	has	have	VBZ
cord-334123-wb45ww7f	142	39	to	to	TO
cord-334123-wb45ww7f	142	40	be	be	VB
cord-334123-wb45ww7f	142	41	at	at	IN
cord-334123-wb45ww7f	142	42	least	least	JJS
cord-334123-wb45ww7f	142	43	formally	formally	RB
cord-334123-wb45ww7f	142	44	considered	consider	VBN
cord-334123-wb45ww7f	142	45	.	.	.
cord-334123-wb45ww7f	143	1	Before	before	IN
cord-334123-wb45ww7f	143	2	the	the	DT
cord-334123-wb45ww7f	143	3	structure	structure	NN
cord-334123-wb45ww7f	143	4	was	be	VBD
cord-334123-wb45ww7f	143	5	solved	solve	VBN
cord-334123-wb45ww7f	143	6	,	,	,
cord-334123-wb45ww7f	143	7	many	many	JJ
cord-334123-wb45ww7f	143	8	predictions	prediction	NNS
cord-334123-wb45ww7f	143	9	were	be	VBD
cord-334123-wb45ww7f	143	10	made	make	VBN
cord-334123-wb45ww7f	143	11	of	of	IN
cord-334123-wb45ww7f	143	12	the	the	DT
cord-334123-wb45ww7f	143	13	folding	folding	NN
cord-334123-wb45ww7f	143	14	of	of	IN
cord-334123-wb45ww7f	143	15	tRNA	tRNA	NNP
cord-334123-wb45ww7f	143	16	.	.	.
cord-334123-wb45ww7f	144	1	None	none	NN
cord-334123-wb45ww7f	144	2	of	of	IN
cord-334123-wb45ww7f	144	3	them	-PRON-	PRP
cord-334123-wb45ww7f	144	4	correctly	correctly	RB
cord-334123-wb45ww7f	144	5	predicted	predict	VBD
cord-334123-wb45ww7f	144	6	the	the	DT
cord-334123-wb45ww7f	144	7	tertiary	tertiary	JJ
cord-334123-wb45ww7f	144	8	structure	structure	NN
cord-334123-wb45ww7f	144	9	that	that	WDT
cord-334123-wb45ww7f	144	10	was	be	VBD
cord-334123-wb45ww7f	144	11	elucidated	elucidate	VBN
cord-334123-wb45ww7f	144	12	by	by	IN
cord-334123-wb45ww7f	144	13	x	x	NN
cord-334123-wb45ww7f	144	14	-	-	NN
cord-334123-wb45ww7f	144	15	ray	ray	NN
cord-334123-wb45ww7f	144	16	diffraction	diffraction	NN
cord-334123-wb45ww7f	144	17	analysis	analysis	NN
cord-334123-wb45ww7f	144	18	.	.	.
cord-334123-wb45ww7f	145	1	This	this	DT
cord-334123-wb45ww7f	145	2	structure	structure	NN
cord-334123-wb45ww7f	145	3	is	be	VBZ
cord-334123-wb45ww7f	145	4	now	now	RB
cord-334123-wb45ww7f	145	5	the	the	DT
cord-334123-wb45ww7f	145	6	basis	basis	NN
cord-334123-wb45ww7f	145	7	for	for	IN
cord-334123-wb45ww7f	145	8	designing	design	VBG
cord-334123-wb45ww7f	145	9	experiments	experiment	NNS
cord-334123-wb45ww7f	145	10	to	to	TO
cord-334123-wb45ww7f	145	11	understand	understand	VB
cord-334123-wb45ww7f	145	12	the	the	DT
cord-334123-wb45ww7f	145	13	interactions	interaction	NNS
cord-334123-wb45ww7f	145	14	of	of	IN
cord-334123-wb45ww7f	145	15	tRNAs	trna	NNS
cord-334123-wb45ww7f	145	16	with	with	IN
cord-334123-wb45ww7f	145	17	proteins	protein	NNS
cord-334123-wb45ww7f	145	18	)	)	-RRB-
cord-334123-wb45ww7f	145	19	.	.	.
cord-334123-wb45ww7f	146	1	In	in	IN
cord-334123-wb45ww7f	146	2	the	the	DT
cord-334123-wb45ww7f	146	3	systems	system	NNS
cord-334123-wb45ww7f	146	4	described	describe	VBN
cord-334123-wb45ww7f	146	5	above	above	RB
cord-334123-wb45ww7f	146	6	,	,	,
cord-334123-wb45ww7f	146	7	the	the	DT
cord-334123-wb45ww7f	146	8	proposed	propose	VBN
cord-334123-wb45ww7f	146	9	pseudoknot	pseudoknot	NNP
cord-334123-wb45ww7f	146	10	secondary	secondary	JJ
cord-334123-wb45ww7f	146	11	structures	structure	NNS
cord-334123-wb45ww7f	146	12	are	be	VBP
cord-334123-wb45ww7f	146	13	highly	highly	RB
cord-334123-wb45ww7f	146	14	schematic	schematic	JJ
cord-334123-wb45ww7f	146	15	.	.	.
cord-334123-wb45ww7f	147	1	NMR	NMR	NNP
cord-334123-wb45ww7f	147	2	analyses	analysis	NNS
cord-334123-wb45ww7f	147	3	of	of	IN
cord-334123-wb45ww7f	147	4	"	"	``
cord-334123-wb45ww7f	147	5	simple	simple	JJ
cord-334123-wb45ww7f	147	6	"	"	''
cord-334123-wb45ww7f	147	7	pseudoknots	pseudoknot	NNS
cord-334123-wb45ww7f	147	8	are	be	VBP
cord-334123-wb45ww7f	147	9	providing	provide	VBG
cord-334123-wb45ww7f	147	10	some	some	DT
cord-334123-wb45ww7f	147	11	of	of	IN
cord-334123-wb45ww7f	147	12	the	the	DT
cord-334123-wb45ww7f	147	13	structural	structural	JJ
cord-334123-wb45ww7f	147	14	parameters	parameter	NNS
cord-334123-wb45ww7f	147	15	that	that	WDT
cord-334123-wb45ww7f	147	16	will	will	MD
cord-334123-wb45ww7f	147	17	guide	guide	VB
cord-334123-wb45ww7f	147	18	model	model	NN
cord-334123-wb45ww7f	147	19	building	building	NN
cord-334123-wb45ww7f	147	20	and	and	CC
cord-334123-wb45ww7f	147	21	design	design	NN
cord-334123-wb45ww7f	147	22	(	(	-LRB-
cord-334123-wb45ww7f	147	23	cf	cf	NN
cord-334123-wb45ww7f	147	24	.	.	.
cord-334123-wb45ww7f	148	1	Wyatt	Wyatt	NNP
cord-334123-wb45ww7f	148	2	et	et	NNP
cord-334123-wb45ww7f	148	3	al	al	NNP
cord-334123-wb45ww7f	148	4	.	.	NNP
cord-334123-wb45ww7f	148	5	,	,	,
cord-334123-wb45ww7f	148	6	1989	1989	CD
cord-334123-wb45ww7f	148	7	)	)	-RRB-
cord-334123-wb45ww7f	148	8	.	.	.
cord-334123-wb45ww7f	149	1	Further	further	JJ
cord-334123-wb45ww7f	149	2	thermodynamic	thermodynamic	JJ
cord-334123-wb45ww7f	149	3	studies	study	NNS
cord-334123-wb45ww7f	149	4	may	may	MD
cord-334123-wb45ww7f	149	5	allow	allow	VB
cord-334123-wb45ww7f	149	6	more	more	RBR
cord-334123-wb45ww7f	149	7	accurate	accurate	JJ
cord-334123-wb45ww7f	149	8	energy	energy	NN
cord-334123-wb45ww7f	149	9	estimates	estimate	NNS
cord-334123-wb45ww7f	149	10	that	that	WDT
cord-334123-wb45ww7f	149	11	can	can	MD
cord-334123-wb45ww7f	149	12	be	be	VB
cord-334123-wb45ww7f	149	13	the	the	DT
cord-334123-wb45ww7f	149	14	basis	basis	NN
cord-334123-wb45ww7f	149	15	for	for	IN
cord-334123-wb45ww7f	149	16	including	include	VBG
cord-334123-wb45ww7f	149	17	pseudoknots	pseudoknot	NNS
cord-334123-wb45ww7f	149	18	in	in	IN
cord-334123-wb45ww7f	149	19	programs	program	NNS
cord-334123-wb45ww7f	149	20	that	that	WDT
cord-334123-wb45ww7f	149	21	compute	compute	VBP
cord-334123-wb45ww7f	149	22	energyminimized	energyminimized	JJ
cord-334123-wb45ww7f	149	23	secondary	secondary	JJ
cord-334123-wb45ww7f	149	24	structures	structure	NNS
cord-334123-wb45ww7f	149	25	(	(	-LRB-
cord-334123-wb45ww7f	149	26	cf	cf	XX
cord-334123-wb45ww7f	149	27	.	.	.
cord-334123-wb45ww7f	150	1	Zucker	Zucker	NNP
cord-334123-wb45ww7f	150	2	,	,	,
cord-334123-wb45ww7f	150	3	1989	1989	CD
cord-334123-wb45ww7f	150	4	)	)	-RRB-
cord-334123-wb45ww7f	150	5	.	.	.
cord-334123-wb45ww7f	151	1	However	however	RB
cord-334123-wb45ww7f	151	2	,	,	,
cord-334123-wb45ww7f	151	3	the	the	DT
cord-334123-wb45ww7f	151	4	data	datum	NNS
cord-334123-wb45ww7f	151	5	of	of	IN
cord-334123-wb45ww7f	151	6	Tang	Tang	NNP
cord-334123-wb45ww7f	151	7	and	and	CC
cord-334123-wb45ww7f	151	8	Draper	Draper	NNP
cord-334123-wb45ww7f	151	9	(	(	-LRB-
cord-334123-wb45ww7f	151	10	1989	1989	CD
cord-334123-wb45ww7f	151	11	)	)	-RRB-
cord-334123-wb45ww7f	151	12	suggest	suggest	VBP
cord-334123-wb45ww7f	151	13	a	a	DT
cord-334123-wb45ww7f	151	14	more	more	RBR
cord-334123-wb45ww7f	151	15	complex	complex	JJ
cord-334123-wb45ww7f	151	16	arrangement	arrangement	NN
cord-334123-wb45ww7f	151	17	for	for	IN
cord-334123-wb45ww7f	151	18	the	the	DT
cord-334123-wb45ww7f	151	19	a	a	DT
cord-334123-wb45ww7f	151	20	operon	operon	NN
cord-334123-wb45ww7f	151	21	mRNA	mRNA	NNP
cord-334123-wb45ww7f	151	22	pseudoknot	pseudoknot	NN
cord-334123-wb45ww7f	151	23	than	than	IN
cord-334123-wb45ww7f	151	24	the	the	DT
cord-334123-wb45ww7f	151	25	basic	basic	JJ
cord-334123-wb45ww7f	151	26	motif	motif	NN
cord-334123-wb45ww7f	151	27	proposed	propose	VBN
cord-334123-wb45ww7f	151	28	by	by	IN
cord-334123-wb45ww7f	151	29	Pleij	Pleij	NNP
cord-334123-wb45ww7f	151	30	et	et	NNP
cord-334123-wb45ww7f	151	31	al	al	NNP
cord-334123-wb45ww7f	151	32	.	.	.
cord-334123-wb45ww7f	152	1	(	(	-LRB-
cord-334123-wb45ww7f	152	2	1985	1985	CD
cord-334123-wb45ww7f	152	3	)	)	-RRB-
cord-334123-wb45ww7f	152	4	.	.	.
cord-334123-wb45ww7f	153	1	In	in	IN
cord-334123-wb45ww7f	153	2	general	general	JJ
cord-334123-wb45ww7f	153	3	,	,	,
cord-334123-wb45ww7f	153	4	it	-PRON-	PRP
cord-334123-wb45ww7f	153	5	is	be	VBZ
cord-334123-wb45ww7f	153	6	likely	likely	JJ
cord-334123-wb45ww7f	153	7	that	that	IN
cord-334123-wb45ww7f	153	8	tertiary	tertiary	JJ
cord-334123-wb45ww7f	153	9	structural	structural	JJ
cord-334123-wb45ww7f	153	10	features	feature	NNS
cord-334123-wb45ww7f	153	11	have	have	VBP
cord-334123-wb45ww7f	153	12	an	an	DT
cord-334123-wb45ww7f	153	13	important	important	JJ
cord-334123-wb45ww7f	153	14	role	role	NN
cord-334123-wb45ww7f	153	15	in	in	IN
cord-334123-wb45ww7f	153	16	the	the	DT
cord-334123-wb45ww7f	153	17	protein	protein	NN
cord-334123-wb45ww7f	153	18	recognition	recognition	NN
cord-334123-wb45ww7f	153	19	and	and	CC
cord-334123-wb45ww7f	153	20	translational	translational	JJ
cord-334123-wb45ww7f	153	21	frameshifting	frameshifting	NN
cord-334123-wb45ww7f	153	22	that	that	WDT
cord-334123-wb45ww7f	153	23	is	be	VBZ
cord-334123-wb45ww7f	153	24	now	now	RB
cord-334123-wb45ww7f	153	25	associated	associate	VBN
cord-334123-wb45ww7f	153	26	with	with	IN
cord-334123-wb45ww7f	153	27	RNA	RNA	NNP
cord-334123-wb45ww7f	153	28	pseudoknots	pseudoknot	NNS
cord-334123-wb45ww7f	153	29	.	.	.
cord-334123-wb45ww7f	154	1	Although	although	IN
cord-334123-wb45ww7f	154	2	in	in	IN
cord-334123-wb45ww7f	154	3	principle	principle	NN
cord-334123-wb45ww7f	154	4	the	the	DT
cord-334123-wb45ww7f	154	5	analytical	analytical	JJ
cord-334123-wb45ww7f	154	6	tools	tool	NNS
cord-334123-wb45ww7f	154	7	are	be	VBP
cord-334123-wb45ww7f	154	8	available	available	JJ
cord-334123-wb45ww7f	154	9	,	,	,
cord-334123-wb45ww7f	154	10	it	-PRON-	PRP
cord-334123-wb45ww7f	154	11	is	be	VBZ
cord-334123-wb45ww7f	154	12	these	these	DT
cord-334123-wb45ww7f	154	13	tertiary	tertiary	JJ
cord-334123-wb45ww7f	154	14	features	feature	NNS
cord-334123-wb45ww7f	154	15	that	that	WDT
cord-334123-wb45ww7f	154	16	will	will	MD
cord-334123-wb45ww7f	154	17	be	be	VB
cord-334123-wb45ww7f	154	18	most	most	RBS
cord-334123-wb45ww7f	154	19	difficult	difficult	JJ
cord-334123-wb45ww7f	154	20	to	to	TO
cord-334123-wb45ww7f	154	21	work	work	VB
cord-334123-wb45ww7f	154	22	out	out	RP
cord-334123-wb45ww7f	154	23	.	.	.
cord-334123-wb45ww7f	155	1	Molecular	molecular	JJ
cord-334123-wb45ww7f	155	2	Biology	Biology	NNP
cord-334123-wb45ww7f	155	3	of	of	IN
cord-334123-wb45ww7f	155	4	RNA	RNA	NNP