id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-316244-s5ua0re3	Park, Mi Hee	Roles of peroxiredoxins in cancer, neurodegenerative diseases and inflammatory diseases	2016-04-26		.txt	text/plain	19183	1015	41	PRDX6 is an oxidative stress inducible protein regulated by Nrf2 and activation of the gene expression was observed in mouse lungs by hyperoxia and in cultured lung epithelial cells following treatment with H 2 O 2 or paraquat . One previous study reported that hypoxia increases AR activity in prostate cancer cells, and that PRDX1, which is upregulated by hypoxia, interacts with AR to enhance the expression of androgen-regulated genes (Chhipa, Lee, Onate, Wu, & Ip, 2009; Park et al., 2006) . PRDX2 is overexpressed in colorectal carcinoma tissues compared with the matched non-cancer colorectal mucosa tissues and that expression is positively associated with tumor metastasis and the TNM stage by regulation of oxidation induced apoptosis (Lu et al., 2014a) . Other researchers also demonstrated that PRDX2 knockdown using a lentiviral vector-mediated specific shRNA inhibited cell growth, stimulated apoptosis, and augmented the production of endogenous ROS that led to an altered expression of proteins associated with the Wnt signaling pathway (Lu et al., 2014b) .	./cache/cord-316244-s5ua0re3.txt	./txt/cord-316244-s5ua0re3.txt