key: cord-282738-aqc9gxlw
authors: Liu, Anding; Li, Ying; Wan, Zhengce; Wang, Wenjie; Lei, Xiaomei; Lv, Yongman
title: Seropositive Prevalence of Antibodies Against SARS-CoV-2 in Wuhan, China
date: 2020-10-23
journal: JAMA Netw Open
DOI: 10.1001/jamanetworkopen.2020.25717
sha: 
doc_id: 282738
cord_uid: aqc9gxlw

This cross-sectional study examines the seropositive prevalence of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, by sex and age group.

Nasal swab specimens were obtained to test for SARS-CoV-2 by real-time RT-PCR.

Total RNAs from nasal swab specimens was extracted by a viral nucleic acid kit 

All statistical analyses were performed using SPSS 20.0. The 95% CI of the seroprevalence was calculated from binomial probabilities using Wilson's methods.

Chisquare test was used for comparison of seroprevalence between groups, and logistic

Association of Public Health Interventions With the Epidemiology of the COVID-19 Outbreak in Wuhan, China

Antibody responses to SARS-CoV-2 in patients with COVID-19

Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients