key: cord-290170-s6wjitfo
authors: Kuhrt, Katy; McMicking, Jess; Nanda, Surabhi; Nelson-Piercy, Catherine; Shennan, Andrew
title: Placental abruption in a twin pregnancy at 32 weeks’ gestation complicated by COVID-19, without vertical transmission to the babies.
date: 2020-05-08
journal: Am J Obstet Gynecol MFM
DOI: 10.1016/j.ajogmf.2020.100135
sha: 
doc_id: 290170
cord_uid: s6wjitfo

nan

Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS), in the third 30 trimester, rather than linked to COVID-19. Other coronavirus spectrum infections have been 31 associated with miscarriage, preterm birth, preeclampsia, caesarean delivery, perinatal death, 32 fetal growth restriction, and placental abruption. 1 On admission she looked unwell, with a pulse rate of 128 bpm, and temperature of 37·1 o C. 99

Laboratory urinalysis was unremarkable. She gave a one-day history of cough, fever and 100 5 mild shortness of breath. Chest x-ray revealed a right sided pleural effusion, and an enlarged 101 globular heart. An echocardiogram performed the same day showed a mild pericardial 102 effusion, and NT-BNP was 28pg/ml (normal <100pg/ml) (done to rule out cardiac failure or 103 cardiomyopathy). Her lymphocytes and platelets had dropped (see table) . On this admission 104 her COVID-19 PCR was repeated (nasal swab) and was positive. She was nursed in isolation, 105 and did not require oxygen. 

Outcome 186 of Coronavirus spectrum infections (SARS, MERS, COVID 1 -19) during 187 pregnancy: a systematic review and meta-analysis

MERS-CoV Infection in a Pregnant Woman in Korea

Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in 198

Possible Vertical Transmission 202 of SARS-CoV-2 From an Infected Mother to Her Newborn

Evaluating the accuracy 206 of different respiratory symptoms in the laboratory diagnosis and monitoring the 207 viral shedding of 2019-nCoV infections

Placental 210 abruption in twin pregnancies, risk factors and perinatal outcomes