id author title date pages extension mime words sentences flesch summary cache txt cord-018103-czjjnlkf Moon, Sanghoon Prediction of Ribosomal -1 Frameshifts in the Escherichia coli K12 Genome 2006 .txt text/plain 2346 180 67 We have developed a web-based application program called FSFinder2 for predicting frameshift sites of general type. In previous work we developed a program called FSFinder (Frameshift Signal Finder) for predicting -1 and +1 frameshift sites [5] . In previous experimental results of testing FSFinder2 on ~190 genomic and partial DNA sequences showed that it predicted frameshift sites efficiently and with greater sensitivity and specificity than other programs, because it focused on the overlapping regions of ORFs and prioritized candidate signals (For -1 frameshifts, sensitivity was 0.88 and specificity 0.97; for +1 frameshifts, sensitivity was 0.91 and specificity 0.94) [5] [6] [7] . coli K12 genome sequence, we found 18,401 frameshift sites after the X XXY YYZ motif. Among these sequences, 11,530 frameshift sites included secondary structure such as pseudoknots or stem-loops. Among these sites, 11 sites including 3 known frameshift sites were considered significant based on the gene length, shape and the length of overlapping region. ./cache/cord-018103-czjjnlkf.txt ./txt/cord-018103-czjjnlkf.txt