id author title date pages extension mime words sentences flesch summary cache txt cord-103080-tzu61nbg Crowe, C. L. Associations of Loneliness and Social Isolation with Healthspan and Lifespan in the US Health and Retirement Study 2020-07-11 .txt text/plain 9816 650 49 We followed N=11,305 US Health and Retirement Study (HRS) participants aged 50-95 from 2006-2014 to measure persistence of exposure to loneliness and social isolation. Studies with measures of loneliness and social isolation at multiple time points can compare healthy aging outcomes among those whose symptoms persist as to those with intermittent exposure. . https://doi.org/10.1101/2020.07.10.20147488 doi: medRxiv preprint chronic disease morbidity and disability collected through 2016, and a measurement of biological aging implemented in data from the 2016 Venous Blood Study. We tested how older adults' experiences of loneliness and social isolation were related to deficits in healthy aging using longitudinal, repeated measures data from the HRS. Panel B shows effect-sizes for analysis of disability and chronic disease (incidence rate ratios (IRR)) from negative binomial regression models including covariate adjustment for age, age-squared, sex, age-sex interactions, race/ethnicity, and a dummy variable coding whether participants were assigned to the subsample of the HRS which first measured loneliness and social isolation in 2006 or 2008. ./cache/cord-103080-tzu61nbg.txt ./txt/cord-103080-tzu61nbg.txt