id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-140624-lphr5prl	Grundel, Sara	How much testing and social distancing is required to control COVID-19? Some insight based on an age-differentiated compartmental model	2020-11-02		.txt	text/plain	8721	532	60	To this end, we develop a compartmental model that accounts for key aspects of the disease: 1) incubation time, 2) age-dependent symptom severity, and 3) testing and hospitalization delays; the model's parameters are chosen based on medical evidence, and, for concreteness, adapted to the German situation. Then, optimal mass-testing and age-dependent social-distancing policies are determined by solving optimal control problems both in open loop and within a model predictive control framework. We address the above questions by proposing a novel compartmental model and using optimal control as well as MPC to compute open and closed-loop social distancing and testing strategies. The model contains three age groups, and it accounts for several of the key challenging characteristics of COVID-19, i.e. 1) the incubation time, 2) different levels of symptom severity depending on age, 3) delay of testing results (and the following self-isolation), and 4) delay of hospitalization.	./cache/cord-140624-lphr5prl.txt	./txt/cord-140624-lphr5prl.txt