id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-274307-kl0uvrbw	Bordet, Régis	Is the drug a scientific, social or political object?	2020-05-23		.txt	text/plain	1392	60	44	Pragmatic trials, adaptive trials using the Bayesian approach, studies with external comparators, trials on small samples, taking into account secondary assessment criteria and the use of biomarkers are all methodological innovations that aim to make the framework of controlled trials more flexible in order to speed up or improve the evaluation of drugs, without abandoning the major and basic principle of comparison [1, 2] . The media outburst against methodology rightly clashes with the convictions of the vast majority of health professionals, who have perhaps not sufficiently integrated the fact that drugs, which they consider above all as a scientific object that is their prerogative, have also become an issue that the social body has taken up. While society may request answers from public authorities and healthcare professionals regarding the risks/benefits balance of drugs, social facts may also influence the medical use or diversion of medicines, or even investment in their development.	./cache/cord-274307-kl0uvrbw.txt	./txt/cord-274307-kl0uvrbw.txt