id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-300653-7ph0r10x	Yin, Xiaowen	An Acute Manic Episode During 2019-nCoV Quarantine	2020-07-20		.txt	text/plain	1986	92	43	CASE PRESENTATION: A 32-year-old woman with direct contact history with her infected colleagues showed elevated mood and increased activity when she was identified negative of nuclear acid amplification test, after experiencing extreme stress in quarantine. CONCLUSION: Quarantine is a major stressful event disrupting social zeitgebers for people who have had contact with infected individuals, especially for vulnerable individuals with a hypersensitive reward system. This model hypothesizes that vulnerability to affective disorders is the result of a hypersensitive reward system that reacts more strongly to external or internal goal-and reward-related life events, and an excessive reward state could be activated by positive goal-striving emotions such as hope and happiness, which in turn lead to a cluster of (hypo) manic psychomotor activation symptoms (Alloy et al., 2015) .This patient's achievement of the goal of being COVID-negative, as an event involving goal attainment, may have triggered excessive responses and the onset of a mania episode. Quarantine is a major stressful event disrupting social zeitgebers for people who have had contact with infected individuals, especially for vulnerable individuals with a hypersensitive reward system.	./cache/cord-300653-7ph0r10x.txt	./txt/cord-300653-7ph0r10x.txt