id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-012408-wcgjyk5m	Gorkin, David U.	An atlas of dynamic chromatin landscapes in mouse fetal development	2020-07-29		.txt	text/plain	17205	985	54	At each stage, we dissected a diverse panel of tissues from multiple litters of embryos and performed two replicates of ATAC-seq and ChIP-seq for each of eight histone modifications chosen to distinguish between different types of functional elements (for example, promoters, enhancers and gene bodies), and activity levels (for example, active, poised and repressed) 13,14 (Fig. 1a , b, Extended Data Fig. 1a, b) . In summary, our results describe a multi-tiered compendium of functional annotations for the developmental mouse genome, including chromatin state maps for 72 distinct tissue-stages, an extensive catalogue of candidate regulatory sequences (many with dynamic temporal activity), enhancer target gene predictions, and a collection of transgenic reporter assays that demonstrates a strong relationship between H3K27ac signal and validation rate.	./cache/cord-012408-wcgjyk5m.txt	./txt/cord-012408-wcgjyk5m.txt